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ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A

Academic Article
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  • Research
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Overview

authors

  • Tillotson, J.
  • Kedzior, M.
  • Guimaraes, L.
  • Ross, A. B.
  • Peters, T. L.
  • Ambrose, A. J.
  • Schmidlin, C. J.
  • Zhang, D. D.
  • Costa-Lotufo, L. V.
  • Rodriguez, A. D.
  • Schatz, J. H.
  • Chapman, Eli

publication date

  • 2017

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Adenosine Triphosphate
  • Biological Products
  • Cell Line, Tumor
  • Cell Survival
  • Dose-Response Relationship, Drug
  • Enzyme Inhibitors
  • Eukaryotic Initiation Factor-4A
  • Humans
  • Molecular Structure
  • Structure-Activity Relationship
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Research

keywords

  • Cancer
  • DEAD box helicase
  • Inhibitor
  • Natural products
  • Translation
  • eIF4A
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Identity

PubMed Central ID

  • PMC5593424

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2017.07.045

PubMed ID

  • 28757063
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Additional Document Info

start page

  • 4082

end page

  • 4085

volume

  • 27

issue

  • 17

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