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Genome editing in hPSCs reveals GATA6 haploinsufficiency and a genetic interaction with GATA4 in human pancreatic development

Academic Article
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Overview

authors

  • Shi, Z.
  • Lee, K.
  • Yang, D.
  • Amin, S.
  • Verma, N.
  • Li, Q. V.
  • Zhu, Z.
  • Soh, C. L.
  • Kumar, R.
  • Evans, T.
  • Chen, Shuibing
  • Huangfu, D. W.

publication date

  • May 2017

journal

  • Cell Stem Cell  Journal

subject areas

  • Animals
  • Cell Differentiation
  • Cell Line
  • Fluorescent Antibody Technique
  • GATA4 Transcription Factor
  • GATA6 Transcription Factor
  • Gene Editing
  • Haploinsufficiency
  • Humans
  • Male
  • Pancreas
  • Pluripotent Stem Cells
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Identity

PubMed Central ID

  • PMC5419850

International Standard Serial Number (ISSN)

  • 1934-5909

Digital Object Identifier (DOI)

  • 10.1016/j.stem.2017.01.001

PubMed ID

  • 28196600
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Additional Document Info

start page

  • 675

end page

  • 688

volume

  • 20

issue

  • 5

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