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Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Academic Article
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Overview

authors

  • Zhang, X.
  • Crowley, V. M.
  • Wucherpfennig, T. G.
  • Dix, Melissa
  • Cravatt, Benjamin

publication date

  • July 2019

journal

  • Nature Chemical Biology  Journal

subject areas

  • Dose-Response Relationship, Drug
  • HEK293 Cells
  • Humans
  • Ligands
  • Molecular Structure
  • Nuclear Proteins
  • Protein Kinase Inhibitors
  • Proteolysis
  • Structure-Activity Relationship
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Identity

PubMed Central ID

  • PMC6592777

International Standard Serial Number (ISSN)

  • 1552-4450

Digital Object Identifier (DOI)

  • 10.1038/s41589-019-0279-5

PubMed ID

  • 31209349
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Additional Document Info

start page

  • 737

end page

  • 746

volume

  • 15

issue

  • 7

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