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Application of parallel multiparametric cell-based FLIPR detection assays for the identification of modulators of the muscarinic acetylcholine receptor 4 (M-4)

Academic Article
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Overview

authors

  • Smith, E.
  • Chase, P.
  • Niswender, C. M.
  • Utley, T. J.
  • Sheffler, D. J.
  • Noetzel, M. J.
  • Lamsal, A.
  • Wood, M. R.
  • Conn, P. J.
  • Lindsley, C. W.
  • Madoux, F.
  • Acosta, M.
  • Scampavia, Louis
  • Spicer, Timothy
  • Hodder, Peter

publication date

  • August 2015

journal

  • Journal of Biomolecular Screening  Journal

subject areas

  • Allosteric Regulation
  • Animals
  • Cell Line
  • Drug Discovery
  • Gene Expression
  • High-Throughput Screening Assays
  • Humans
  • Muscarinic Agonists
  • Muscarinic Antagonists
  • Receptor, Muscarinic M4
  • Small Molecule Libraries
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Research

keywords

  • GPCR
  • muscarinic
  • parallel screening
  • positive allosteric modulators
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Identity

PubMed Central ID

  • PMC4659430

International Standard Serial Number (ISSN)

  • 1087-0571

Digital Object Identifier (DOI)

  • 10.1177/1087057115581770

PubMed ID

  • 25877150
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Additional Document Info

start page

  • 858

end page

  • 868

volume

  • 20

issue

  • 7

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