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CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells

Academic Article
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Overview

authors

  • Wang, C. K.
  • Yang, S. C.
  • Hsu, S. C.
  • Chang, F. P.
  • Lin, Y. T.
  • Chen, Shang-Fu
  • Cheng, C. L.
  • Hsiao, M.
  • Lu, F. L.
  • Lu, J.

publication date

  • December 2017

journal

  • Free Radical Biology and Medicine  Journal

subject areas

  • Animals
  • Biological Assay
  • Cell Line
  • Cell Proliferation
  • Feeder Cells
  • Fibroblasts
  • Gene Expression Regulation
  • Glutamate-Cysteine Ligase
  • Glutathione
  • Human Embryonic Stem Cells
  • Humans
  • Mice
  • Mice, Inbred C57BL
  • NF-E2-Related Factor 2
  • RNA, Small Interfering
  • Signal Transduction
  • Teratoma
  • gamma-Glutamylcyclotransferase
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Research

keywords

  • CHAC2
  • Glutathione
  • Human embryonic stem cell
  • Reactive oxygen species
  • Self-renewal
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Identity

International Standard Serial Number (ISSN)

  • 0891-5849

Digital Object Identifier (DOI)

  • 10.1016/j.freeradbiomed.2017.10.345

PubMed ID

  • 29054545
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Additional Document Info

start page

  • 439

end page

  • 451

volume

  • 113

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