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Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition

Academic Article
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Overview

authors

  • Nazir, S.
  • Gadi, I.
  • Al-Dabet, M. M.
  • Elwakiel, A.
  • Kohli, S.
  • Ghosh, S.
  • Manoharan, J.
  • Ranjan, S.
  • Bock, F.
  • Braun-Dullaeus, R. C.
  • Esmon, C. T.
  • Huber, T. B.
  • Camerer, E.
  • Dockendorff, C.
  • Griffin, John
  • Isermann, B.
  • Shahzad, K.

publication date

  • December 2017

journal

  • Blood  Journal

subject areas

  • Animals
  • Animals, Newborn
  • Anticoagulants
  • Apoptosis
  • Cells, Cultured
  • Cytoprotection
  • Immunoblotting
  • Inflammasomes
  • Kidney
  • Mechanistic Target of Rapamycin Complex 1
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Myocardial Reperfusion Injury
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • Protective Agents
  • Protein C
  • Receptor, PAR-1
  • Reperfusion Injury
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Identity

International Standard Serial Number (ISSN)

  • 0006-4971

Digital Object Identifier (DOI)

  • 10.1182/blood-2017-05-782102

PubMed ID

  • 28882883
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Additional Document Info

start page

  • 2664

end page

  • 2677

volume

  • 130

issue

  • 24

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