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Methodology for protein-ligand binding studies: application to a model for drug resistance, the HIV/FIV protease system

Academic Article
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Overview

related to degree

  • Dominy, Brian, Ph.D. in Biology, Scripps Research 1995 - 2001

authors

  • Dominy, Brian
  • Brooks III, C. L.

publication date

  • August 1999

journal

  • Proteins-Structure Function and Genetics  Journal

subject areas

  • Animals
  • Aspartic Acid Endopeptidases
  • Catalytic Domain
  • Cats
  • Drug Resistance, Microbial
  • HIV Protease
  • HIV Protease Inhibitors
  • Humans
  • Immunodeficiency Virus, Feline
  • Ligands
  • Models, Biological
  • Protein Binding
  • Static Electricity
  • Thermodynamics
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Research

keywords

  • FIV
  • HIV
  • binding free energy
  • drug resistance
  • protease
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Identity

International Standard Serial Number (ISSN)

  • 0887-3585

Digital Object Identifier (DOI)

  • 10.1002/(SICI)1097-0134(19990815)36:3<318::AID-PROT6>3.0.CO;2-K

PubMed ID

  • 10409825
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Additional Document Info

start page

  • 318

end page

  • 331

volume

  • 36

issue

  • 3

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