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Chemoproteomics-enabled discovery of a potent and selective inhibitor of the DNA repair protein MGMT

Academic Article
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Overview

authors

  • Wang, C.
  • Abegg, D.
  • Hoch, D. G.
  • Adibekian, Alexander

publication date

  • February 2016

journal

  • Angewandte Chemie-International Edition  Journal

subject areas

  • DNA Repair
  • Drug Discovery
  • Enzyme Inhibitors
  • O(6)-Methylguanine-DNA Methyltransferase
  • Proteomics
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Research

keywords

  • MGMT
  • activity-based protein profiling
  • drug discovery
  • mass spectrometry
  • proteomics
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Identity

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.201511301

PubMed ID

  • 26798972
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Additional Document Info

start page

  • 2911

end page

  • 2915

volume

  • 55

issue

  • 8

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