recent publications

• academic article

  • Teixeira, L. K., Wang, X., Li, Y., Ekholm-Reed, S., Wu, X., Wang, P., Reed, S. I. Cyclin E deregulation promotes loss of specific genomic regions Current Biology  2015 25:1327-1333  DOI:10.1016/j.cub.2015.03.022  PMID:25959964  PMCID:PMC4439338
  • Phad, G. E., Vázquez Bernat, N., Feng, Y., Ingale, J., Martinez Murillo, P. A., O'Dell, S., Li, Y., Mascola, J. R., Sundling, C., Wyatt, R. T., Karlsson Hedestam, G. B. Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization Journal of Immunology  2015 194:5903-5914  DOI:10.4049/jimmunol.1500122  PMID:25964491  PMCID:PMC4458414
  • Xu, K., Ma, L., Li, Y., Wang, F., Zheng, G. Y., Sun, Z., Jiang, F., Chen, Y., Liu, H., Dang, A., Chen, X., Chun, J., et al. Genetic and functional evidence supports LPAR1 as a susceptibility gene for hypertension Hypertension  2015 66:641-646  DOI:10.1161/hypertensionaha.115.05515  PMID:26123684
  • Garitaonandia, I., Amir, H., Boscolo, F. S., Wambua, G. K., Schultheisz, H. L., Sabatini, K., Morey, R., Waltz, S., Wang, Y. C., Tran, H., Leonardo, T. R., Nazor, K., et al. Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions PLoS One  2015 10:e0118307  DOI:10.1371/journal.pone.0118307  PMID:25714340  PMCID:PMC4340884
  • Barbian, H. J., Decker, J. M., Bibollet-Ruche, F., Galimidi, R. P., West Jr., A. P., Learn, G. H., Parrish, N. F., Iyer, S. S., Li, Y., Pace, C. S., Song, R., Huang, Y., et al. Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas MBio  2015 6:e00296  DOI:10.1128/mBio.00296-15  PMID:25900654  PMCID:PMC4453581
  • Majzoub, R. N., Ewert, K. K., Jacovetty, E. L., Carragher, B., Potter, C. S., Li, Y., Safinya, C. R. Patterned threadlike micelles and DNA-tethered nanoparticles: A structural study of PEGylated cationic liposome-DNA assemblies Langmuir  2015 31:7073-7083  DOI:10.1021/acs.langmuir.5b00993  PMID:26048043  PMCID:PMC4554524
  • McDonald, W., Funatogawa, C., Li, Y., Chen, Y., Szundi, I., Fee, J. A., Stout, C. D., Einarsdottir, O. Conserved glycine 232 in the ligand channel of ba(3) cytochrome oxidase from Thermus thermophilus Biochemistry  2014 53:4467-4475  DOI:10.1021/bi500289h  PMID:24937405  PMCID:PMC4216187
  • Wang, H., Li, Y., Truong, L. N., Shi, L. Z., Hwang, P. Y. H., He, J., Do, J., Cho, M. J., Li, H., Negrete, A., Shiloach, J., Berns, M. W., et al. CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity Molecular Cell  2014 54:1012-1021  DOI:10.1016/j.molcel.2014.04.012  PMID:24837675  PMCID:PMC4105207
  • Truong, L. N., Li, Y., Sun, E., Ang, K., Hwang, P. Y. H., Wu, X. Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication Journal of Biological Chemistry  2014 289:28910-28923  DOI:10.1074/jbc.M114.576488  PMID:25160628  PMCID:PMC4200250
  • Bizon, C., Spiegel, M., Chasse, S. A., Gizer, I. R., Li, Y., Malc, E. P., Mieczkowski, P. A., Sailsbery, J. K., Wang, X., Ehlers, C. L., Wilhelmsen, K. C. Variant calling in low-coverage whole genome sequencing of a Native American population sample BMC Genomics  2014 15:85  DOI:10.1186/1471-2164-15-85  PMID:24479562  PMCID:PMC3914019
  • Liao, G. Y., Li, Y., Xu, B. Ablation of TrkB expression in RGS9-2 cells leads to hyperphagic obesity Molecular Metabolism  2013 2:491-497  DOI:10.1016/j.molmet.2013.08.002  PMID:24327964  PMCID:PMC3854990
  • Park, G. Y., Lee, Y. G., Berdyshev, E., Nyenhuis, S., Du, J., Fu, P., Gorshkova, I. A., Li, Y., Chung, S., Karpurapu, M., Deng, J., Ranjan, R., et al. Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation American Journal of Respiratory and Critical Care Medicine  2013 188:928-940  DOI:10.1164/rccm.201306-1014OC  PMID:24050723  PMCID:PMC3826286
  • Li, Y., Moretto-Zita, M., Soncin, F., Wakeland, A., Wolfe, L., Leon-Garcia, S., Pandian, R., Pizzo, D., Cui, L., Nazor, K., Loring, J. F., Crum, C. P., et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state Development  2013 140:3965-3976  DOI:10.1242/dev.092155  PMID:24004950  PMCID:PMC3775414
  • Franceschini, N., Fox, E., Zhang, Z., Edwards, T. L., Nalls, M. A., Sung, Y. J., Tayo, B. O., Sun, Y. V., Gottesman, O., Adeyemo, A., Johnson, A. D., Young, J. H., et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations American Journal of Human Genetics  2013 93:545-554  DOI:10.1016/j.ajhg.2013.07.010  PMID:23972371  PMCID:PMC3769920
  • Truong, L. N., Li, Y., Shi, L. Z., Hwang, P. Y., He, J., Wang, H., Razavian, N., Berns, M. W., Wu, X. Microhomology-mediated end joining and homologous recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells Proceedings of the National Academy of Sciences of the United States of America  2013 110:7720-7725  DOI:10.1073/pnas.1213431110  PMID:23610439  PMCID:PMC3651503
  • Tong, S., Zhu, X., Li, Y., Shi, M., Zhang, J., Bourgeois, M., Yang, H., Chen, X., Recuenco, S., Gomez, J., Chen, L. M., Johnson, A., et al. New world bats harbor diverse influenza A viruses PLoS Pathogens  2013 9:e1003657  DOI:10.1371/journal.ppat.1003657  PMID:24130481  PMCID:PMC3794996
  • Koziol, J. A., Griffin, N. M., Long, F., Li, Y., Latterich, M., Schnitzer, J. E. On protein abundance distributions in complex mixtures Proteome Science  2013 11:5  DOI:10.1186/1477-5956-11-5  PMID:23360617  PMCID:PMC3599228
  • Li, Y., Karagoz, G. E., Seo, Y. H., Zhang, T., Jiang, Y., Yu, Y., Duarte, A. M. S., Schwartz, S. J., Boelens, R., Carroll, K., Rudiger, S. G. D., Sun, D. Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90 Journal of Nutritional Biochemistry  2012 23:1617-1626  DOI:10.1016/j.jnutbio.2011.11.004  PMID:22444872  PMCID:PMC3386376
  • Lu, C. S., Truong, L. N., Aslanian, A., Shi, L. Z., Li, Y., Hwang, P. Y. H., Koh, K. H., Hunter, T., Yates, J. R., Berns, M. W., Wu, X. The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination Journal of Biological Chemistry  2012 287:43984-43994  DOI:10.1074/jbc.M112.421545  PMID:23115235  PMCID:PMC3527981
  • Prasad, A., Jia, Y., Chakraborty, A., Li, Y., Jain, S. K., Zhong, J., Roy, S. G., Loison, F., Mondal, S., Sakai, J., Blanchard, C., Snyder, S. H., et al. Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling Nature Immunology  2011 12:752-760  DOI:10.1038/ni.2052  PMID:21685907  PMCID:PMC3140608