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Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis

Academic Article
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  • Research
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Overview

authors

  • Knight, J. S.
  • Luo, W.
  • O'Dell, A. A.
  • Yalavarthi, S.
  • Zhao, W.
  • Subramanian, V.
  • Guo, C.
  • Grenn, R. C.
  • Thompson, Paul
  • Eitzman, D. T.
  • Kaplan, M. J.

publication date

  • March 2014

journal

  • Circulation Research  Journal

subject areas

  • Animals
  • Aortic Diseases
  • Apolipoproteins E
  • Atherosclerosis
  • Autoantibodies
  • Citrulline
  • Dendritic Cells
  • Drug Evaluation, Preclinical
  • Enzyme Inhibitors
  • Extracellular Space
  • Histones
  • Hydrolases
  • Immunity, Innate
  • Interferon-alpha
  • L-Selectin
  • Lipids
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Neutropenia
  • Neutrophils
  • Ornithine
  • Photochemical Processes
  • Protein Processing, Post-Translational
  • Receptor, Interferon alpha-beta
  • Sinus of Valsalva
  • Tunica Intima
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Research

keywords

  • atherosclerosis
  • immunology
  • interferon-
  • neutrophils
  • protein-arginine deiminase
  • thrombosis
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Identity

International Standard Serial Number (ISSN)

  • 0009-7330

Digital Object Identifier (DOI)

  • 10.1161/circresaha.114.303312

PubMed ID

  • 24425713
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Additional Document Info

start page

  • 947

end page

  • 956

volume

  • 114

issue

  • 6

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