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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

Academic Article
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Overview

authors

  • Regalado, E. L.
  • Kozlowski, M. C.
  • Curto, J. M.
  • Ritter, T.
  • Mazzotti, A. R.
  • Hamper, B. C.
  • Spilling, C. D.
  • Mannino, M. P.
  • Wan, L.
  • Yu, Jin-Quan
  • Liu, J.
  • Welch, C. J.
  • Campbell, M. G.

publication date

  • 2014

journal

  • Organic & Biomolecular Chemistry  Journal

abstract

  • The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.

subject areas

  • Chemical Fractionation
  • Chemistry Techniques, Synthetic
  • Chromatography, High Pressure Liquid
  • Chromatography, Supercritical Fluid
  • Drug Industry
  • Laboratories
  • Organic Chemicals
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Identity

International Standard Serial Number (ISSN)

  • 1477-0520

Digital Object Identifier (DOI)

  • 10.1039/c3ob42195c

PubMed ID

  • 24589831
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Additional Document Info

start page

  • 2161

end page

  • 2166

volume

  • 12

issue

  • 14

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