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In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects

Academic Article
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Overview

authors

  • Ignatowska-Jankowska, B. M.
  • Ghosh, S.
  • Crowe, M. S.
  • Kinsey, S. G.
  • Niphakis, M. J.
  • Abdullah, R. A.
  • Tao, Q.
  • O'Neal, S. T.
  • Walentiny, D. M.
  • Wiley, J. L.
  • Cravatt, Benjamin
  • Lichtman, A. H.

publication date

  • March 2014

journal

  • British Journal of Pharmacology  Journal

subject areas

  • Analgesics
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal
  • Benzodioxoles
  • Brain
  • Cannabinoids
  • Chromatography, Liquid
  • Enzyme Inhibitors
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Molecular Mimicry
  • Monoacylglycerol Lipases
  • Piperidines
  • Tandem Mass Spectrometry
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Research

keywords

  • 2-arachidonoylglycerol
  • CB1
  • CB2
  • allodynia
  • cannabinoid
  • gastric haemorrhage
  • inflammatory pain
  • monoacylglycerol lipase
  • mouse
  • neuropathic pain
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Identity

PubMed Central ID

  • PMC3954480

International Standard Serial Number (ISSN)

  • 0007-1188

Digital Object Identifier (DOI)

  • 10.1111/bph.12298

PubMed ID

  • 23848221
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Additional Document Info

start page

  • 1392

end page

  • 1407

volume

  • 171

issue

  • 6

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