recent publications
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academic article
- Tan, Y. X., Peters, D. S., Walsh, S. I., Holcomb, M., Santos-Martins, D., Forli, S., Romesberg, F. E. Initial Analysis of the Arylomycin D Antibiotics Journal of Natural Products 2020 83:2112-2121 DOI:10.1021/acs.jnatprod.9b01174 PMID:32614583
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Walsh, S. I., Peters, D. S., Smith, P. A., Craney, A., Dix, M. M., Cravatt, B. F., Romesberg, F. E.
Inhibition of protein secretion in Escherichia coli and sub-MIC effects of arylomycin antibiotics
Antimicrobial Agents and Chemotherapy
2019
63:e01253-18
DOI:10.1128/aac.01253-18
PMID:30420476
PMCID:PMC6355593
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Yeh, C. H., Walsh, S. I., Craney, A., Tabor, M. G., Voica, A. F., Adhikary, R., Morris, S. E., Romesberg, F. E.
Optimization of a β-lactam scaffold for antibacterial activity via the inhibition of bacterial type I signal peptidase
ACS Medicinal Chemistry Letters
2018
9:376-380
DOI:10.1021/acsmedchemlett.8b00064
PMID:29670704
PMCID:PMC5900324
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Walsh, S. I., Craney, A., Romesberg, F. E.
Not just an antibiotic target: Exploring the role of type I signal peptidase in bacterial virulence
Bioorganic & Medicinal Chemistry
2016
24:6370-6378
DOI:10.1016/j.bmc.2016.09.048
PMID:27769673
PMCID:PMC5279723