academic article

• Unwin, N., Fujiyoshi, Y. Gating movement of acetylcholine receptor caught by plunge-freezing Journal of Molecular Biology  2012 422:617-634  DOI:10.1016/j.jmb.2012.07.010  PMID:22841691  PMCID:PMC3443390
• Fisher, L. S., Ward, A., Milligan, R. A., Unwin, N., Potter, C. S., Carragher, B. A helical processing pipeline for EM structure determination of membrane proteins Methods  2011 55:350-362  DOI:10.1016/j.ymeth.2011.09.013  PMID:21964395  PMCID:PMC3262078
• Fujiyoshi, Y., Unwin, N. Electron crystallography of proteins in membranes Current Opinion in Structural Biology  2008 18:587-592  DOI:10.1016/j.sbi.2008.07.005  PMID:18755273  PMCID:PMC2651081
• O'Brien, J., Unwin, N. Organization of spines on the dendrites of purkinje cells Proceedings of the National Academy of Sciences of the United States of America  2006 103:1575-1580  DOI:10.1073/pnas.0507884103  PMID:16423897  PMCID:PMC1360541
• Unwin, N. Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution Journal of Molecular Biology  2005 346:967-989  DOI:10.1016/j.jmb.2004.12.031  PMID:15701510
• Unwin, N. Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy FEBS Letters  2003 555:91-95  DOI:10.1016/s0014-5793(03)01084-6  PMID:14630325
• Miyazawa, A., Fujiyoshi, Y., Unwin, N. Structure and gating mechanism of the acetylcholine receptor pore Nature  2003 423:949-955  DOI:10.1038/nature01748  PMID:12827192
• Unwin, N., Miyazawa, A., Li, J., Fujiyoshi, Y. Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the a subunits Journal of Molecular Biology  2002 319:1165-1176  DOI:10.1016/s0022-2836(02)00381-9  PMID:12079355
• Unwin, N. The croonian lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission Philosophical Transactions of the Royal Society of London Series B-Biological Sciences  2000 355:1813-1829  DOI:10.1098/rstb.2000.0737  PMID:11205343  PMCID:PMC1692909
• Tierney, M. L., Unwin, N. Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor Journal of Molecular Biology  2000 303:185-196  DOI:10.1006/jmbi.2000.4137  PMID:11023785
• Miyazawa, A., Fujiyoshi, Y., Stowell, M., Unwin, N. Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall Journal of Molecular Biology  1999 288:765-786  DOI:10.1006/jmbi.1999.2721  PMID:10329178
• Stowell, M. H. B., Miyazawa, A., Unwin, N. Macromolecular structure determination by electron microscopy: New advances and recent results Current Opinion in Structural Biology  1998 8:595-600  DOI:10.1016/s0959-440x(98)80150-4  PMID:9818263
• Unwin, N. The nicotinic acetylcholine receptor of the torpedo electric ray Journal of Structural Biology  1998 121:181-190  DOI:10.1006/jsbi.1997.3949  PMID:9615437
• Beroukhim, R., Unwin, N. Distortion correction of tubular crystals: Improvements in the acetylcholine receptor structure Ultramicroscopy  1997 70:57-81  DOI:10.1016/s0304-3991(97)00070-3  PMID:9440347
• Unwin, N. Projection structure of the nicotinic acetylcholine receptor: Distinct conformations of the alpha subunits Journal of Molecular Biology  1996 257:586-596  DOI:10.1006/jmbi.1996.0187  PMID:8648626
• Beroukhim, R., Unwin, N. Three-dimensional location of the main immunogenic region of the acetylcholine receptor Neuron  1995 15:323-331  DOI:10.1016/0896-6273(95)90037-3  PMID:7544140
• Unwin, N. Acetylcholine receptor channel imaged in the open state Nature  1995 373:37-43  DOI:10.1038/373037a0  PMID:7800037
• Berriman, J., Unwin, N. Analysis of transient structures by cryomicroscopy combined with rapid mixing of spray droplets Ultramicroscopy  1994 56:241-252  DOI:10.1016/0304-3991(94)90012-4  PMID:7831735
• Li, M., Unwin, N., Stauffer, K. A., Jan, Y. N., Jan, L. Y. Images of purified shaker potassium channels Current Biology  1994 4:110-115  DOI:10.1016/s0960-9822(94)00026-6  PMID:7953509
• Unwin, N. Nicotinic acetylcholine-receptor at 9 Å resolution Journal of Molecular Biology  1993 229:1101-1124  DOI:10.1006/jmbi.1993.1107  PMID:8445638
• Unwin, N. Neurotransmitter action - opening of ligand-gated ion channels Cell  1993 72:31-41  DOI:10.1016/s0092-8674(05)80026-1  PMID:7679054
• Hyman, A. A., Salser, S., Drechsel, D. N., Unwin, N., Mitchison, T. J. Role of gtp hydrolysis in microtubule dynamics - information from a slowly hydrolyzable analog, gmpcpp Molecular Biology of the Cell  1992 3:1155-1167  PMID:1421572  PMCID:PMC275679
• Stauffer, K. A., Kumar, N. M., Gilula, N. B., Unwin, N. Isolation and purification of gap junction channels Journal of Cell Biology  1991 115:141-150  DOI:10.1083/jcb.115.1.141  PMID:1655801
• Toyoshima, C., Unwin, N. Three-dimensional structure of the acetylcholine receptor by cryoelectron microscopy and helical image reconstruction Journal of Cell Biology  1990 111:2623-2635  DOI:10.1083/jcb.111.6.2623  PMID:2277076  PMCID:PMC2116367
• Unwin, N. The structure of ion channels in membranes of excitable cells Neuron  1989 3:665-676  DOI:10.1016/0896-6273(89)90235-3  PMID:2484344
• Toyoshima, C., Unwin, N. Ion channel of acetylcholine-receptor reconstructed from images of postsynaptic membranes Nature  1988 336:247-250  DOI:10.1038/336247a0  PMID:2461515
• Milks, L. C., Kumar, N. M., Houghten, R., Unwin, N., Gilula, N. B. Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations EMBO Journal  1988 7:2967-2975  PMID:2460334  PMCID:PMC454678
• Unwin, N., Toyoshima, C., Kubalek, E. Arrangement of the acetylcholine-receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized torpedo postsynaptic membranes Journal of Cell Biology  1988 107:1123-1138  DOI:10.1083/jcb.107.3.1123  PMID:3417777
• Gogol, E., Unwin, N. Organization of connexons in isolated rat-liver gap-junctions Biophysical Journal  1988 54:105-112  DOI:10.1016/S0006-3495(88)82935-7  PMID:3416022  PMCID:PMC1330320
• Sikerwar, S. S., Unwin, N. Three-dimensional structure of gap junctions in fragmented plasma membranes from rat liver Biophysical Journal  1988 54:113-119  DOI:10.1016/S0006-3495(88)82936-9  PMID:3416023  PMCID:PMC1330321
• Lyon, M. K., Unwin, P. N. T. Two-dimensional structure of the light-harvesting chlorophyll a/b complex by cryoelectron microscopy Journal of Cell Biology  1988 106:1515-1523  DOI:10.1083/jcb.106.5.1515  PMID:2453515  PMCID:PMC2115055
• Toyoshima, C., Unwin, N. Contrast transfer for frozen-hydrated specimens - determination from pairs of defocused images Ultramicroscopy  1988 25:279-291  DOI:10.1016/0304-3991(88)90003-4  PMID:3188279
• Unwin, N. Design and action of cell communication channels Chemica Scripta  1987 27B:47-51
• Kubalek, E., Ralston, S., Lindstrom, J., Unwin, N. Location of subunits within the acetylcholine-receptor by electron image-analysis of tubular crystals from torpedo-marmorata Journal of Cell Biology  1987 105:9-18  DOI:10.1083/jcb.105.1.9  PMID:3611197
• Unwin, P. N. T. Gap junction structure and the control of cell-to-cell communication Ciba Foundation Symposia  1987 125:78-91  PMID:2435472
• Unwin, N. The use of cryoelectron microscopy in elucidating molecular design and mechanisms Annals of the New York Academy of Sciences  1986 483:1-4  DOI:10.1111/j.1749-6632.1986.tb34485.x  PMID:3471117
• Milligan, R. A., Unwin, P. N. T. Location of exit channel for nascent protein in 80S ribosome Nature  1986 319:693-695  DOI:10.1038/319693a0  PMID:3951541
• Brisson, A., Unwin, P. N. T. Quaternary structure of the acetylcholine-receptor Nature  1985 315:474-477  DOI:10.1038/315474a0  PMID:4000275
• Taylor, K. A., Milligan, R. A., Raeburn, C., Unwin, P. N. T. A cold stage for the philips em300 electron-microscope Ultramicroscopy  1984 13:185-189  DOI:10.1016/0304-3991(84)90197-9  PMID:6485128
• Milligan, R. A., Brisson, A., Unwin, P. N. T. Molecular-structure determination of crystalline specimens in frozen aqueous-solutions Ultramicroscopy  1984 13:1-9  DOI:10.1016/0304-3991(84)90051-2  PMID:6474593
• Unwin, N., Henderson, R. The structure of proteins in biological membranes Scientific American  1984 250:78-94  PMID:6318309
• Brisson, A., Unwin, P. N. T. Tubular crystals of acetylcholine-receptor Journal of Cell Biology  1984 99:1202-1211  DOI:10.1083/jcb.99.4.1202  PMID:6480689
• Unwin, P. N. T., Ennis, P. D. Two configurations of a channel-forming membrane protein Nature  1984 307:609-613  DOI:10.1038/307609a0  PMID:6320017
• Unwin, P. N. T., Ennis, P. D. Calcium-mediated changes in gap junction structure - evidence from the low-angle x-ray pattern Journal of Cell Biology  1983 97:1459-1466  DOI:10.1083/jcb.97.5.1459  PMID:6630291
• Amos, L. A., Henderson, R., Unwin, P. N. T. Three-dimensional structure determination by electron microscopy of two-dimensional crystals Progress in Biophysics & Molecular Biology  1983 39:183-231  DOI:10.1016/0079-6107(83)90017-2  PMID:6289376
• Unwin, P. N. T., Milligan, R. A. A large particle associated with the perimeter of the nuclear-pore complex Journal of Cell Biology  1982 93:63-75  DOI:10.1083/jcb.93.1.63  PMID:7068761
• Kuhlbrandt, W., Unwin, P. N. T. Distribution of rna and protein in crystalline eukaryotic ribosomes Journal of Molecular Biology  1982 156:431-448  DOI:10.1016/0022-2836(82)90259-5  PMID:6811751
• Milligan, R. A., Unwin, P. N. T. In vitro crystallization of ribosomes from chick embryos Journal of Cell Biology  1982 95:648-653  DOI:10.1083/jcb.95.2.648  PMID:7142299  PMCID:PMC2112976
• Unwin, P. N. T., Zampighi, G. Structure of the junction between communicating cells Nature  1980 283:545-549  DOI:10.1038/283545a0  PMID:7354837
• Unwin, P. N. T. Attachment of ribosome crystals to intracellular membranes Journal of Molecular Biology  1979 132:69-84  DOI:10.1016/0022-2836(79)90496-0  PMID:117113
• Zampighi, G., Unwin, P. N. T. Two forms of isolated gap junctions Journal of Molecular Biology  1979 135:451-464  DOI:10.1016/0022-2836(79)90446-7  PMID:537084
• Unwin, P. N. T., Taddei, C. Packing of ribosomes in crystals from lizard lacerta-sicula Journal of Molecular Biology  1977 114:491-506  DOI:10.1016/0022-2836(77)90174-7  PMID:562417
• Henderson, R., Unwin, P. N. T. Structure of purple membrane from halobacterium-halobium Biophysics of Structure and Mechanism  1977 3:121-121  DOI:10.1007/bf00535804  PMID:890047
• Unwin, P. N. T. Three-dimensional model of membrane-bound ribosomes obtained by electron microscopy Nature  1977 269:118-122  DOI:10.1038/269118a0  PMID:909577
• Mandelkow, E. M., Mandelkow, E., Unwin, N., Cohen, C. Tubulin hoops Nature  1977 265:655-657  DOI:10.1038/265655a0  PMID:859570
• Unwin, P. N. T. Beef liver catalase structure - interpretation of electron micrographs Journal of Molecular Biology  1975 98:235-242  DOI:10.1016/s0022-2836(75)80111-2  PMID:1195381
• Unwin, P. N. T., Henderson, R. Molecular structure determination by electron microscopy of unstained crystalline specimens Journal of Molecular Biology  1975 94:425-440  DOI:10.1016/0022-2836(75)90212-0  PMID:1236957
• Henderson, R., Unwin, P. N. T. Three-dimensional model of purple membrane obtained by electron microscopy Nature  1975 257:28-32  DOI:10.1038/257028a0  PMID:1161000
• Unwin, P. N. T. Electron microscopy of the stacked disk aggregate of tobacco mosaic virus protein. Ii. The influence of electron irradiation of the stain distribution Journal of Molecular Biology  1974 87:657-670  DOI:10.1016/0022-2836(74)90076-x  PMID:4139268
• Unwin, P. N. T., Klug, A. Electron microscopy of the stacked disk aggregate of tobacco mosaic-virus protein: 1. Three-dimensional image reconstruction Journal of Molecular Biology  1974 87:641-650  DOI:10.1016/0022-2836(74)90075-8  PMID:4427373
• Unwin, P. N. T. New electron-microscope imaging method for enhancing detail in thin biological specimens Zeitschrift für Naturforschung Section A-A Journal of Physical Sciences  1974 A 29:158-163
• Unwin, P. N. T. Phase-contrast electron-microscopy of biological-materials Journal of Microscopy  1973 98:299-312  PMID:4126993
• Unwin, P. N. T. Electron microscopy of biological specimens by means of an electrostatic phase plate Proceedings of the Royal Society of London Series a-Mathematical and Physical Sciences  1972 329:327-359  DOI:10.1098/rspa.1972.0116
• Unwin, P. N. T., Muguruma, J. Electron-microscope observations on defect structure of ice Physica Status Solidi a-Applied Research  1972 14:207-216  DOI:10.1002/pssa.2210140125
• Unwin, P. N. T. Phase contrast and interference microscopy with the electron microscope Philosophical Transactions of the Royal Society of London Series B-Biological Sciences  1971 261:95-104  DOI:10.1098/rstb.1971.0039  PMID:4399209
• Unwin, P. N. T., Muguruma, J. Transmission electron microscopy of ice Journal of Applied Physics  1971 42:3640-3641  DOI:10.1063/1.1660782
• Unwin, P. N. T. An electrostatic phase plate for the electron microscope Berichte Der Bunsen-Gesellschaft Fur Physikalische Chemie  1970 74:1137-1141  DOI:10.1002/bbpc.19700741110
• Unwin, P. N. T., Wilkins, M. A. A technique for the preparation of thin foils from regions near cracks in massive bodies Journal of Physics E-Scientific Instruments  1969 2:736  DOI:10.1088/0022-3735/2/8/435
• Unwin, P. N. T., Smith, G. C. Microstructure and mechanical properties of al-6% zn-3% mg Journal of the Institute of Metals  1969 97:299-310
• Unwin, P. N. T., Nicholson, R. B. The nucleation and initial stages of growth of grain boundary precipitates in al-zn-mg and al-mg alloys Acta Metallurgica  1969 17:1379-1393  DOI:10.1016/0001-6160(69)90155-2
• Unwin, P. N. T., Lorimer, G. W., Nicholson, R. B. The origin of the grain boundary precipitate free zone Acta Metallurgica  1969 17:1363-1377  DOI:10.1016/0001-6160(69)90154-0
• Cundy, S. L., Metherell, A. J. F., Nicholson, R. B., Unwin, P. N. T., Whelan, M. J. Studies of segregation and the initial stages of precipitation at grain boundaries in an aluminium 7 wt. Percent magnesium alloy with an energy analysing electron microscope Proceedings of the Royal Society of London Series a-Mathematical and Physical Sciences  1968 307:267-281  DOI:10.1098/rspa.1968.0189