recent publications
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academic article
- Burton, D. R., Topol, E. J. Toward superhuman SARS-CoV-2 immunity? Nature Medicine 2021 27:5-6 DOI:10.1038/s41591-020-01180-x PMID:33257892
- Quer, G., Radin, J. M., Gadaleta, M., Baca-Motes, K., Ariniello, L., Ramos, E., Kheterpal, V., Topol, E. J., Steinhubl, S. R. Wearable sensor data and self-reported symptoms for COVID-19 detection Nature Medicine 2021 27:73-77 DOI:10.1038/s41591-020-1123-x PMID:33122860
- Topol, E. Which Country Has the World's Best Health Care? Nature 2020 582:331-333
- Milstein, A., Topol, E. J. Computer vision's potential to improve health care Lancet 2020 395:1537-1537 DOI:10.1016/s0140-6736(20)31090-4 PMID:32416778
- Keane, P. A., Topol, E. J. Digital medicine Medicine and meteorology: Cloud, connectivity, and care Lancet 2020 395:1334-1334 PMID:32334694
- Nagendran, M., Chen, Y., Lovejoy, C. A., Gordon, A. C., Komorowski, M., Harvey, H., Topol, E. J., Ioannidis, J. P. A., Collins, G. S., Maruthappu, M. Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies BMJ-British Medical Journal 2020 368 DOI:10.1136/bmj.m689 PMID:32213531 PMCID:PMC7190037
- Dorsey, E. R., Topol, E. J. Telemedicine 2020 and the next decade Lancet 2020 395:859-859 PMID:32171399
- Berzin, T. M., Topol, E. J. Adding artificial intelligence to gastrointestinal endoscopy Lancet 2020 395:485-485 PMID:32061286
- Quer, G., Gouda, P., Galarnyk, M., Topol, E. J., Steinhubl, S. R. Inter- and intraindividual variability in daily resting heart rate and its associations with age, sex, sleep, BMI, and time of year: Retrospective, longitudinal cohort study of 92,457 adults PLoS One 2020 15 DOI:10.1371/journal.pone.0227709 PMID:32023264 PMCID:PMC7001906
- Muse, E. D., Topol, E. J. A brighter future for kidney disease? Lancet 2020 395:179-179 PMID:31954451
- Jaiswal, S. J., Quer, G., Galarnyk, M., Steinhubl, S. R., Topol, E. J., Owens, R. L. Association of Sleep Duration and Variability With Body Mass Index Sleep Measurements in a Large US Population of Wearable Sensor Users JAMA Internal Medicine 2020 DOI:10.1001/jamainternmed.2020.2834 PMID:32926073 PMCID:PMC7490746
- Topol, E. J. COVID-19 can affect the heart Science 2020 370:408-409 DOI:10.1126/science.abe2813 PMID:32967937
- Verghese, A., Topol, E. Courage in a climate of fear Science Translational Medicine 2020 12 DOI:10.1126/scitranslmed.abf2461 PMID:33077677
- Muse, E. D., Topol, E. J. Digital medicine Guiding ultrasound image capture with artificial intelligence Lancet 2020 396:749-749 PMID:32919501
- Kanchan, K., Iyer, K., Yanek, L. R., Carcamo-Orive, I., Taub, M. A., Malley, C., Baldwin, K., Becker, L. C., Broeckel, U., Cheng, L. Z., Cowan, C., D'Antonio, M., et al. Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program Stem Cell Research 2020 46 DOI:10.1016/j.scr.2020.101803 PMID:32442913
- Norgeot, B., Quer, G., Beaulieu-Jones, B. K., Torkamani, A., Dias, R., Gianfrancesco, M., Arnaout, R., Kohane, I. S., Saria, S., Topol, E., Obermeyer, Z., Yu, B., et al. Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist Nature Medicine 2020 26:1320-1324 DOI:10.1038/s41591-020-1041-y PMID:32908275 PMCID:PMC7538196
- Harvey, H., Topol, E. J. More than meets the AI: refining image acquisition and resolution Lancet 2020 396:1479-1479 PMID:33160557
- Oran, D. P., Topol, E. J. Prevalence of Asymptomatic SARS-CoV-2 Infection A Narrative Review Annals of Internal Medicine 2020 173:362-367 DOI:10.7326/m20-3012 PMID:32491919 PMCID:PMC7281624
- Angrist, M., Barrangou, R., Baylis, F., Brokowski, C., Burgio, G., Caplan, A., Chapman, C. R., Church, G. M., Cook-Deegan, R., Cwik, B., Doudna, J. A., Evans, J. H., et al. Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing Crispr Journal 2020 3:332-349 DOI:10.1089/crispr.2020.29106.man PMID:33095048
- Topol, E. J. Welcoming new guidelines for AI clinical research Nature Medicine 2020 26:1318-1320 DOI:10.1038/s41591-020-1042-x PMID:32908274
- Salfati, E. L., Spencer, E. G., Topol, S. E., Muse, E. D., Rueda, M., Lucas, J. R., Wagner, G. N., Campman, S., Topol, E. J., Torkamani, A. Re-analysis of whole-exome sequencing data uncovers novel diagnostic variants and improves molecular diagnostic yields for sudden death and idiopathic diseases Genome Medicine 2019 11 DOI:10.1186/s13073-019-0702-2 PMID:31847883 PMCID:PMC6916453
- Keane, P., Topol, E. Digital medicine Reinventing the eye exam Lancet 2019 394:2141-2141
- Regev, A., Zhang, F., Jaffee, E., Farrar, J., Nkengasong, J., Topol, E., Partridge, L., Mundel, T., Tabernero, J., Sabeti, P., Toreele, E. Looking forward 25 years: the future of medicine Nature Medicine 2019 25:1804-1807 DOI:10.1038/s41591-019-0693-y PMID:31806889
- Esteva, A., Topol, E. Can skin cancer diagnosis be transformed by AI? Lancet 2019 394:1795-1795
- Chan, J., Raju, S. C., Topol, E. Towards a tricorder for diagnosing paediatric conditions Lancet 2019 394:907-907 DOI:10.1016/s0140-6736(19)32087-2
- Muse, E. D., Topol, E. J. Digital orthodoxy of human data collection Lancet 2019 394:556-556 PMID:31423988
- Topol, E. J. Everybody wants to go to heaven but nobody wants to die: bioethics and the transformation of health care in america Nature 2019 572:308-309 DOI:10.1038/d41586-019-02412-y
- Pandey, A. C., Topol, E. J. Dispense with supplements for improving heart outcomes Annals of Internal Medicine 2019 171:216-217 DOI:10.7326/m19-1498 PMID:31284306
- Topol, E. J. Deep learning detects impending organ injury Nature 2019 572:36-37 DOI:10.1038/d41586-019-02308-x PMID:31367025
- Topol, E., Lee, K. F. It takes a planet Nature Biotechnology 2019 37:858-861 DOI:10.1038/s41587-019-0214-z PMID:31375799
- Oran, D. P., Topol, E. J. Digital medicine The rise of the virtualist Lancet 2019 394:17-17 DOI:10.1377/hblog20180319.150005
- Topol, E. Man and machine medicine Scientist 2019 33:61-61
- Topol, E. J. A decade of digital medicine innovation Science Translational Medicine 2019 11 DOI:10.1126/scitranslmed.aaw7610 PMID:31243153
- Torkamani, A., Topol, E. Polygenic risk scores expand to obesity Cell 2019 177:518-520 DOI:10.1016/j.cell.2019.03.051 PMID:31002792
- Waalen, J., Peters, M., Ranamukhaarachchi, D., Li, J., Ebner, G., Senkowsky, J., Topol, E. J., Steinhubl, S. R. Real world usage characteristics of a novel mobile health self-monitoring device: Results from the Scanadu Consumer Health Outcomes (SCOUT) Study PLoS One 2019 14 DOI:10.1371/journal.pone.0215468 PMID:30990860 PMCID:PMC6467418
- Evangelista, L., Steinhubl, S. R., Topol, E. J. Digital health care for older adults Lancet 2019 393:1493-1493 DOI:10.1016/s0140-6736(19)30800-1 PMID:30983579
- Jaiswal, S. J., Topol, E. J., Steinhubl, S. R. Digitising the way to better sleep health Lancet 2019 393:639-639 DOI:10.1001/jamapsychiatry.2018.2745 PMID:30782334
- Ensign, S. F., Baca-Motes, K., Steinhubl, S. R., Topol, E. J. Characteristics of the modern-day physician house call Medicine 2019 98 DOI:10.1097/md.0000000000014671 PMID:30813215 PMCID:PMC6408061
- Kumar, A., Thomas, S. K., Wong, K. C., Lo Sardo, V., Cheah, D. S., Hou, Y. H., Placone, J. K., Tenerelli, K. P., Ferguson, W. C., Torkamani, A., Topol, E. J., Baldwin, K. K., et al. Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes Nature Biomedical Engineering 2019 3:137-146 DOI:10.1038/s41551-018-0344-5
- Hamideh, D., Arellano, B., Topol, E. J., Steinhubl, S. R. Your digital nutritionist Lancet 2019 393:19-19 DOI:10.1016/s0140-6736(18)33170-2 PMID:30614448
- Spencer, E. G., Topol, E. J. Direct to consumer fitness DNA testing Clinical Chemistry 2019 65:45-47 DOI:10.1373/clinchem.2018.287326 PMID:30274978
- Topol, E. J. High-performance medicine: the convergence of human and artificial intelligence Nature Medicine 2019 25:44-56 DOI:10.1038/s41591-018-0300-7 PMID:30617339
- Wineinger, N. E., Barrett, P. M., Zhang, Y., Irfanullah, I., Muse, E. D., Steinhubl, S. R., Topol, E. J. Identification of paroxysmal atrial fibrillation subtypes in over 13,000 individuals Heart Rhythm 2019 16:26-30 DOI:10.1016/j.hrthm.2018.08.012 PMID:30118885
- Lo Sardo, V., Chubukov, P., Ferguson, W., Kumar, A., Teng, E. L., Duran, M., Zhang, L., Cost, G., Engler, A. J., Urnov, F., Topol, E. J., Torkamani, A., et al. Unveiling the role of the most impactful cardiovascular risk locus through haplotype editing Cell 2018 175:1796-1810 DOI:10.1016/j.cell.2018.11.014 PMID:30528432
- Tarassenko, L., Topol, E. J. Monitoring jet engines and the health of people JAMA-Journal of the American Medical Association 2018 320:2309-2310 DOI:10.1001/jama.2018.16558 PMID:30453330
- Wang, F., Wang, I. Z., Ellis, S., Archacki, S., Barnard, J., Hubbard, C., Topol, E. J., Chen, Q., Wang, Q. K. Analysis of causal effect of APOA5 variants on premature coronary artery disease Annals of Human Genetics 2018 82:437-447 DOI:10.1111/ahg.12273 PMID:30024021 PMCID:PMC6188800
- Torkamani, A., Topol, E. Your genome, on demand MIT Technology Review 2018 121:20-21
- Radin, J. M., Topol, E. J., Steinhubl, S. R. A digital toolkit for improved maternal health Lancet 2018 392:1107-1107 DOI:10.1016/s0140-6736(18)32294-3
- Steinhubl, S. R., Topol, E. J. A skin patch for sensing blood pressures Nature Biomedical Engineering 2018 2:633-634 DOI:10.1038/s41551-018-0296-9
- Quer, G., Nikzad, N., Chieh, A., Normand, A., Vegreville, M., Topol, E. J., Steinhubl, S. R. Home monitoring of blood pressure: short-term changes during serial measurements for 56398 subjects Ieee Journal of Biomedical and Health Informatics 2018 22:1691-1698 DOI:10.1109/jbhi.2017.2776946 PMID:29989995 PMCID:PMC6053341
- Torkamani, A., Wineinger, N. E., Topol, E. J. The personal and clinical utility of polygenic risk scores Nature Reviews Genetics 2018 19:581-590 DOI:10.1038/s41576-018-0018-x PMID:29789686
- Steinhubl, S. R., Topol, E. J. Now we're talking: bringing a voice to digital medicine Lancet 2018 392:627-627
- Modena, B. D., Bellahsen, O., Nikzad, N., Chieh, A., Parikh, N., Dufek, D. M., Ebner, G., Topol, E. J., Steinhubl, S. Advanced and accurate mobile health tracking devices record new cardiac vital signs Hypertension 2018 72:503-510 DOI:10.1161/hypertensionaha.118.11177 PMID:29967036 PMCID:PMC6044460
- Song, M. Y., Steinhubl, S. R., Topol, E. J. Digital medicine: The beginning of the end of fingersticks? Lancet 2018 392:203-203 DOI:10.1016/s0140-6736(18)31576-9
- Steinhubl, S. R., Waalen, J., Edwards, A. M., Ariniello, L. M., Mehta, R. R., Ebner, G. S., Carter, C., Baca-Motes, K., Felicione, E., Sarich, T., Topol, E. J. Effect of a home-based wearable continuous ECG monitoring patch on detection of undiagnosed atrial fibrillation the mSToPS randomized clinical trial JAMA-Journal of the American Medical Association 2018 320:146-155 DOI:10.1001/jama.2018.8102 PMID:29998336
- Muse, E. D., Torkamani, A., Topol, E. J. When genomics goes digital Lancet 2018 391:2405-2405 DOI:10.1038/s41576-018-0018-x PMID:29916375
- Topol, E. Bad blood secrets and lies in a Silicon Valley startup Nature 2018 557:306-307
- Kim, K. I., Nikzad, N., Quer, G., Wineinger, N. E., Vegreville, M., Normand, A., Schmidt, N., Topol, E. J., Steinhubl, S. Real world home blood pressure variability in over 56,000 individuals with nearly 17 million measurements American Journal of Hypertension 2018 31:566-573 DOI:10.1093/ajh/hpx221 PMID:29365036 PMCID:PMC5905665
- Telenti, A., Steinhubl, S. R., Topol, E. J. Rethinking the medical record Lancet 2018 391:1013-1013 PMID:29565009
- Mikk, K. A., Sleeper, H. A., Topol, E. Patient data ownership reply JAMA-Journal of the American Medical Association 2018 319:935-936 DOI:10.1001/jama.2017.21688 PMID:29509862
- Jha, S., Topol, E. J. Information and artificial intelligence Journal of the American College of Radiology 2018 15:509-511 DOI:10.1016/j.jacr.2017.12.025
- Steinhubl, S. R., Kim, K. I., Ajayi, T., Topol, E. J. Virtual care for improved global health Lancet 2018 391:419-419 PMID:29407024
- Dharajiya, N. G., Grosu, D. S., Farkas, D. H., McCullough, R. M., Almasri, E., Sun, Y., Kim, S. K., Jensen, T. J., Saldivar, J. S., Topol, E. J., van den Boom, D., Ehrich, M. Incidental detection of maternal neoplasia in noninvasive prenatal testing Clinical Chemistry 2018 64:329-335 DOI:10.1373/clinchem.2017.277517 PMID:28982650
- Muse, E. D., Wineinger, N. E., Spencer, E. G., Peters, M., Henderson, R., Zhang, Y., Barrett, P. M., Rivera, S. P., Wohlgemuth, J. G., Devlin, J. J., Shiffman, D., Topol, E. J. Validation of a genetic risk score for atrial fibrillation: A prospective multicenter cohort study PLoS Medicine 2018 15 DOI:10.1371/journal.pmed.1002525 PMID:29534064 PMCID:PMC5849279
- Bansal, V., Gassenhuber, J., Phillips, T., Oliveira, G., Harbaugh, R., Villarasa, N., Topol, E. J., Seufferlein, T., Boehm, B. O. Spectrum of mutations in monogenic diabetes genes identified from high-throughput DNA sequencing of 6888 individuals BMC Medicine 2017 15 DOI:10.1186/s12916-017-0977-3 PMID:29207974 PMCID:PMC5717832
- Steinhubl, S. R., McGovern, P., Dylan, J., Topol, E. J. The digitised clinical trial Lancet 2017 390:2135-2135 PMID:29143747
- Mikk, K. A., Sleeper, H. A., Topol, E. J. The pathway to patient data ownership and better health JAMA-Journal of the American Medical Association 2017 318:1433-1434 DOI:10.1001/jama.2017.12145 PMID:28973063
- Muse, E. D., Kramer, E. R., Wang, H. Y., Barrett, P., Parviz, F., Novotny, M. A., Lasken, R. S., Jatkoe, T. A., Oliveira, G., Peng, H. F., Lu, J., Connelly, M. C., et al. A whole blood molecular signature for acute myocardial infarction Scientific Reports 2017 7 DOI:10.1038/s41598-017-12166-0 PMID:28947747 PMCID:PMC5612952
- Torkamani, A., Andersen, K. G., Steinhubl, S. R., Topol, E. J. High-Definition Medicine Cell 2017 170:828-843 DOI:10.1016/j.cell.2017.08.007 PMID:28841416
- Quer, G., Muse, E. D., Nikzad, N., Topol, E. J., Steinhubl, S. R. Digital medicine: Augmenting diagnostic vision with AI Lancet 2017 390:221-221
- Barrett, P. M., Steinhubl, S. R., Muse, E. D., Topol, E. J. Digitising the mind Lancet 2017 389:1877-1877 PMID:28513442
- Muse, E. D., Barrett, P. M., Steinhubl, S. R., Topol, E. J. Towards a smart medical home Lancet 2017 389:358-358 PMID:28137686
- Topol, E. J. Is there an ICD-10 code for hyperbole? JAMA-Journal of the American Medical Association 2017 317:10-11 PMID:28030677
- Guo, Y., Wang, F., Li, L., Gao, H., Arckacki, S., Wang, I. Z., Barnard, J., Ellis, S., Hubbard, C., Topol, E. J., Chen, Q., Wang, Q. K. Genome-wide linkage analysis of large multiple multigenerational families identifies novel genetic loci for coronary rrtery disease Scientific Reports 2017 7 DOI:10.1038/s41598-017-05381-2 PMID:28710368 PMCID:PMC5511258
- Lo Sardo, V., Ferguson, W., Erikson, G. A., Topol, E. J., Baldwin, K. K., Torkamani, A. Influence of donor age on induced pluripotent stem cells Nature Biotechnology 2017 35:69-74 DOI:10.1038/nbt.3749 PMID:27941802
- Jha, S., Topol, E. J. Adapting to artificial intelligence radiologists and pathologists as information specialists JAMA-Journal of the American Medical Association 2016 316:2353-2354 DOI:10.1001/jama.2016.17438 PMID:27898975
- Kim, J. Y., Wineinger, N. E., Taitel, M., Radin, J. M., Akinbosoye, O., Jiang, J., Nikzad, N., Orr, G., Topol, E., Steinhubl, S. Self-monitoring utilization patterns among individuals in an incentivized program for healthy behaviors Journal of Medical Internet Research 2016 18:83-97 DOI:10.2196/jmir.6371 PMID:27856407
- Radin, J. M., Topol, E. J., Andersen, K. G., Steinhubl, S. R. A laboratory in your pocket Lancet 2016 388:1875-1875 PMID:27751390
- Torkamani, A., Muse, E. D., Spencer, E. G., Rueda, M., Wagner, G. N., Lucas, J. R., Topol, E. J. Molecular autopsy for sudden unexpected death JAMA-Journal of the American Medical Association 2016 316:1492-1494 PMID:27727376
- Dorsey, E. R., Topol, E. J. State of Telehealth REPLY New England Journal of Medicine 2016 375:1400-1400
- Topol, E. The evangelist of individualized medicine Technology Review 2016 119:91-92
- Topol, E. Digital medicine: empowering both patients and clinicians Lancet 2016 388:740-741 PMID:27560260
- Steinhubl, S. R., Muse, E. D., Barrett, P. M., Topol, E. J. Off the cuff : rebooting blood pressure treatment Lancet 2016 388:749-749 PMID:27560266
- Gollamudi, S. S., Topol, E. J., Wineinger, N. E. A framework for smartphone-enabled, patient-generated health data analysis PeerJ 2016 4 DOI:10.7717/peerj.2284 PMID:27547580 PMCID:PMC4975026
- Topol, E. J. Money back guarantees for non-reproducible results? BMJ-British Medical Journal 2016 353 DOI:10.1136/bmj.i2770 PMID:27221803
- Erikson, G. A., Bodian, D. L., Rueda, M., Molparia, B., Scott, E. R., Scott-Van Zeeland, A. A., Topol, S. E., Wineinger, N. E., Niederhuber, J. E., Topol, E. J., Torkamani, A. Whole-genome sequencing of a healthy aging cohort Cell 2016 165:1002-1011 DOI:10.1016/j.cell.2016.03.022 PMID:27114037 PMCID:PMC4860090
- Steinhubl, S. R., Mehta, R. R., Ebner, G. S., Ballesteros, M. M., Waalen, J., Steinberg, G., Van Crocker Jr., P., Felicione, E., Carter, C. T., Edmonds, S., Honcz, J. P., Miralles, G. D., et al. Rationale and design of a home-based trial using wearable sensors to detect asymptomatic atrial fibrillation in a targeted population: The mHealth Screening To Prevent Strokes (mSToPS) trial American Heart Journal 2016 175:77-85 DOI:10.1016/j.ahj.2016.02.011 PMID:27179726
- Barrett, P. M., Topol, E. J. Smartphone Medicine It Professional 2016 18:52-54
- Barrett, P. M., Topol, E. J. To truly look inside Lancet 2016 387:1268-1269 PMID:27035018
- Bloss, C. S., Wineinger, N. E., Peters, M., Boeldt, D. L., Ariniello, L., Kim, J. Y., Sheard, J., Komatireddy, R., Barrett, P., Topol, E. J. A prospective randomized trial examining health care utilization in individuals using multiple smartphone-enabled biosensors PeerJ 2016 4 DOI:10.7717/peerj.1554 PMID:26788432 PMCID:PMC4715435
- Dorsey, E. R., Topol, E. J. State of telehealth New England Journal of Medicine 2016 375:154-161 DOI:10.1056/NEJMra1601705 PMID:27410924
- Wilbanks, J. T., Topol, E. J. Stop the privatization of health data Nature 2016 535:345-348 PMID:27443724
- Filkins, B. L., Kim, J. Y., Roberts, B., Armstrong, W., Miller, M. A., Hultner, M. L., Castillo, A. P., Ducom, J. C., Topol, E. J., Steinhubl, S. R. Privacy and security in the era of digital health: what should translational researchers know and do about it? American Journal of Translational Research 2016 8:1560-1580 PMID:27186282 PMCID:PMC4859641
- Lauer, M. S., Krumholz, H. M., Topol, E. J. Time for a prepublication culture in clinical research? Lancet 2015 386:2447-2449 DOI:10.1016/S0140-6736(15)01177-0 PMID:26738703 PMCID:PMC5082701
- Bloss, C. S., Zeeland, A. A. S. V., Topol, S. E., Darst, B. F., Boeldt, D. L., Erikson, G. A., Bethel, K. J., Bjork, R. L., Friedman, J. R., Hwynn, N., Patay, B. A., Pockros, P. J., et al. A genome sequencing program for novel undiagnosed diseases Genetics in Medicine 2015 17:995-1001 DOI:10.1038/gim.2015.21 PMID:25790160 PMCID:PMC4575596
- Harper, A. R., Nayee, S., Topol, E. J. Protective alleles and modifier variants in human health and disease Nature Reviews Genetics 2015 16:689-701 DOI:10.1038/nrg4017 PMID:26503796
- Braenne, I., Civelek, M., Vilne, B., Di Narzo, A., Johnson, A. D., Zhao, Y., Reiz, B., Codoni, V., Webb, T. R., Asl, H. F., Hamby, S. E., Zeng, L., et al. Prediction of causal candidate genes in coronary artery disease loci Arteriosclerosis Thrombosis and Vascular Biology 2015 35:2207-2217 DOI:10.1161/atvbaha.115.306108 PMID:26293461 PMCID:PMC4583353
- Steinhubl, S. R., Topol, E. J. Moving from digitalization to digitization in cardiovascular care why is it important, and what could it mean for patients and providers? Journal of the American College of Cardiology 2015 66:1489-1496 DOI:10.1016/j.jacc.2015.08.006 PMID:26403346 PMCID:PMC4583658
- Rifai, N., Topol, E., Chan, E., Lo, Y. M. D., Wittwer, C. T. Disruptive innovation in laboratory medicine Clinical Chemistry 2015 61:1129-1132 DOI:10.1373/clinchem.2015.243667 PMID:26152753
- Teirstein, P., Topol, E. J. Maintenance of certification and the interstate medical licensure compact reply JAMA-Journal of the American Medical Association 2015 314:952-952 PMID:26325571
- Kish, L. J., Topol, E. J. Unpatients-why patients should own their medical data Nature Biotechnology 2015 33:921-924 PMID:26348958
- Guillot, J., Topol, E., Brynjolfsson, E. Fighting for Zach Technology Review 2015 118:10-11
- Topol, E. Watch This Technology Review 2015 118:11-11
- Teirstein, P. S., Topol, E. J. The role of maintenance of certification programs in governance and professionalism JAMA-Journal of the American Medical Association 2015 313:1809-1810 DOI:10.1001/jama.2015.3576 PMID:25965219 PMCID:PMC4751049
- Topol, E. J. The big medical data miss: challenges in establishing an open medical resource Nature Reviews Genetics 2015 16:253-254 DOI:10.1038/nrg3943 PMID:25882108
- Steinhubl, S. R., Muse, E. D., Topol, E. J. The emerging field of mobile health Science Translational Medicine 2015 7 DOI:10.1126/scitranslmed.aaa3487 PMID:25877894 PMCID:PMC4748838
- Steinhubl, S. R., Wineingeri, N. E., Patel, S., Boeldt, D. L., Mackellar, G., Porter, V., Redmond, J. T., Muse, E. D., Nicholson, L., Chopra, D., Topol, E. J. Cardiovascular and nervous system changes during meditation Frontiers in Human Neuroscience 2015 9 DOI:10.3389/fnhum.2015.00145 PMID:25852526 PMCID:PMC4364161
- Boeldt, D. L., Schork, N. J., Topol, E. J., Bloss, C. S. Influence of individual differences in disease perception on consumer response to direct-to-consumer genomic testing Clinical Genetics 2015 87:225-232 DOI:10.1111/cge.12419 PMID:24798746 PMCID:PMC4758676
- Topol, E. J., Steinhubl, S. R., Torkamani, A. Digital medical tools and sensors JAMA-Journal of the American Medical Association 2015 313:353-354 DOI:10.1001/jama.2014.17125 PMID:25626031 PMCID:PMC4751024
- Boeldt, D. L., Wineinger, N. E., Waalen, J., Gollamudi, S., Grossberg, A., Steinhubl, S. R., McCollister-Slipp, A., Rogers, M. A., Silvers, C., Topol, E. J. How consumers and physicians view new medical technology: comparative survey Journal of Medical Internet Research 2015 17:e215 DOI:10.2196/jmir.4456 PMID:26369254 PMCID:PMC4642377
- Steinhubl, S. R., Topol, E. J. RESPONSE: Time for the pager to enter retirement Journal of the American College of Cardiology 2014 64:2705-2705
- Gao, H., Li, L., Rao, S., Shen, G., Xi, Q., Chen, S., Zhang, Z., Wang, K., Ellis, S. G., Chen, Q., Topol, E. J., Wang, Q. K. Genome-wide linkage scan identifies two novel genetic loci for coronary artery disease: in GeneQuest families PLoS One 2014 9:e113935 DOI:10.1371/journal.pone.0113935 PMID:25485937 PMCID:PMC4259362
- Tang, W. H. W., Topol, E. J., Fan, Y., Wu, Y., Cho, L., Stevenson, C., Ellis, S. G., Hazen, S. L. Prognostic value of estimated functional capacity incremental to cardiac biomarkers in stable cardiac patients Journal of the American Heart Association 2014 3:e000960 DOI:10.1161/jaha.114.000960
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- Lincoff, A. M., Tcheng, J. E., Califf, R. M., Bass, T., Popma, J. J., Teirstein, P. S., Kleiman, N. S., Hattel, L. J., Anderson, H. V., Ferguson, J. J., Cabot, C. F., Anderson, K. M., et al. Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein iib/iiia receptor antibody fragment abciximab (c7e3 fab) during percutaneous coronary revascularization American Journal of Cardiology 1997 79:286-291 PMID:9036746
- Holmes, D. R., Califf, R. M., VandeWerf, F., Berger, P. B., Bates, E. R., Simoons, M. L., White, H. D., Thompson, T. D., Topol, E. J. Difference in countries' use of resources and clinical outcome for patients with cardiogenic shock after myocardial infarction: Results from the gusto trial Lancet 1997 349:75-78 DOI:10.1016/s0140-6736(96)03031-0 PMID:8996417
- Betriu, A., Phillips, H., Ellis, S., Topol, E., Califf, R., VanderWerf, F., Ardissino, D., Armstrong, P. W., Aylward, P., Bates, E., Beatt, K., Cheseboro, J., et al. A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction New England Journal of Medicine 1997 336:1621-1628 PMID:9173270
- Brener, S. J., Ellis, S. G., AppersonHansen, C., Leon, M. B., Topol, E. J. Comparison of stenting and balloon angioplasty for narrowings in aortocoronary saphenous vein conduits in place for more than five years American Journal of Cardiology 1997 79:13-18 PMID:9024728
- Krucoff, M. W., Green, C. L., Langer, A., Klootwijk, P., Trollinger, K. M., Pope, J. E., Armstrong, P. W., Simoons, M. L., Topol, E. J., Califf, R. M. Continuous 12-lead st-segment recovery predicts outcome in acute myocardial infarction better than "snapshot" angiograms of timi flow Journal of Electrocardiology 1997 30:167-167
- Mahaffey, K. W., Granger, C. B., Toth, C. A., White, H. D., Stebbins, A. L., Barbash, G. I., Vahanian, A., Topol, E. J., Califf, R. M. Diabetic retinopathy should not be a contraindication to thrombolytic therapy for acute myocardial infarction: Review of ocular hemorrhage incidence and location in the gusto-i trial Journal of the American College of Cardiology 1997 30:1606-1610 DOI:10.1016/s0735-1097(97)00394-x PMID:9385883
- Woodfield, S. L., Lundergan, C. F., Reiner, J. S., Thompson, M. A., Rohrbeck, S. C., Deychak, Y., Smith, J. O., Burton, J. R., McCarthy, W. F., Califf, R. M., White, H. D., Weaver, W. D., et al. Gender and acute myocardial infarction: Is there a different response to thrombolysis? Journal of the American College of Cardiology 1997 29:35-42 PMID:8996292
- Topol, E. J. Reperfusion for acute myocardial infarction: 1997 and beyond Cleveland Clinic Journal of Medicine 1997 64:9-12 PMID:9014377
- Labinaz, M., Sketch, M. H., Stebbins, A. L., DeFranco, A. C., Holmes, D. R., Kleiman, N. S., Betriu, A., Rutsch, W. R., Vahanian, A., Topol, E. J., Califf, R. M. Thrombolytic therapy for patients with prior percutaneous transluminal coronary angioplasty and subsequent acute myocardial infarction American Journal of Cardiology 1996 78:1338-1344 DOI:10.1016/s0002-9149(96)00654-6 PMID:8970403
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- Rashid, J., Eisenberg, M. J., Topol, E. J. Cocaine-induced aortic dissection American Heart Journal 1996 132:1301-1304 DOI:10.1016/s0002-8703(96)90486-x PMID:8969594
- Aylward, P. E., Wilcox, R. G., Horgan, J. H., White, H. D., Granger, C. B., Califf, R. M., Topol, E. J. Relation of increased arterial blood pressure to mortality and stroke in the context of contemporary thrombolytic therapy for acute myocardial infarction - a randomized trial Annals of Internal Medicine 1996 125:891-900 PMID:8967669
- LeBreton, H., Plow, E. F., Topol, E. J. Role of platelets in restenosis after percutaneous coronary revascularization Journal of the American College of Cardiology 1996 28:1643-1651 PMID:8962547
- Lefkovits, J., Malycky, J. L., Rao, J. S., Hart, C. E., Plow, E. F., Topol, E. J., Nicolini, F. A. Selective inhibition of factor xa is more efficient than factor viia-tissue factor complex blockade at facilitating coronary thrombolysis in the canine model Journal of the American College of Cardiology 1996 28:1858-1865 PMID:8962577
- Gent, M., Beaumont, D., Blanchard, J., Bousser, M. G., Coffman, J., Easton, J. D., Hampton, J. R., Harker, L. A., Janzon, L., Kusmierek, J. J. E., Panak, E., Roberts, R. S., et al. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (caprie) Lancet 1996 348:1329-1339 PMID:8918275
- Rao, A. K., Sun, L., Chesebro, J. H., Fuster, V., Harrington, R. A., Schwartz, D., Gallo, P., Matos, D., Topol, E. J. Distinct effects of recombinant desulfatohirudin (revasc) and heparin on plasma levels of fibrinopeptide a and prothrombin fragment f1.2 in unstable angina - a multicenter trial Circulation 1996 94:2389-2395 PMID:8921778
- Brener, S. J., Leya, F. S., AppersonHansen, C., Cowley, M. J., Califf, R. M., Topol, E. J. A comparison of debulking versus dilatation of bifurcation coronary arterial narrowings (from the caveat i trial) American Journal of Cardiology 1996 78:1039-1041 DOI:10.1016/s0002-9149(96)00531-0 PMID:8916485
- Schulman, S. P., GoldschmidtClermont, P. J., Topol, E. J., Califf, R. M., Navetta, F. I., Willerson, J. T., Chandra, N. C., Guerci, A. D., Ferguson, J. J., Harrington, R. A., Lincoff, A. M., Yakubov, S. J., et al. Effects of integrelin, a platelet glycoprotein iib/iiia receptor antagonist, in unstable angina - a randomized multicenter trial Circulation 1996 94:2083-2089 PMID:8901655
- Obrien, J. E., Peterson, E. D., Keeler, G. P., Berdan, L. G., Ohman, E. M., Faxon, D. P., Jacobs, A. K., Topol, E. J., Califf, R. M. Relation between estrogen replacement therapy and restenosis after percutaneous coronary interventions Journal of the American College of Cardiology 1996 28:1111-1118 DOI:10.1016/s0735-1097(96)00306-3 PMID:8890803
- Ohman, E. M., Armstrong, P. W., Christenson, R. H., Granger, C. B., Katus, H. A., Hamm, C. W., Ohanesian, M. A., Wagner, G. S., Kleiman, N. S., Harrell, F. E., Califf, R. M., Topol, E. J. Cardiac troponin t levels for risk stratification in acute myocardial ischemia New England Journal of Medicine 1996 335:1333-1341 DOI:10.1056/nejm199610313351801 PMID:8857016
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- White, H. D., Barbash, G. I., Califf, R. M., Simes, R. J., Granger, C. B., Weaver, W. D., Kleiman, N. S., Aylward, P. E., Gore, J. M., Vahanian, A., Lee, K. L., Ross, A. M., et al. Age and outcome with contemporary thrombolytic therapy - results from the gusto-i trial Circulation 1996 94:1826-1833 PMID:8873656
- Horrigan, M. C. G., MacIsaac, A. I., Nicolini, F. A., Vince, D. G., Lee, P., Ellis, S. G., Topol, E. J. Reduction in myocardial infarct size by basic fibroblast growth factor after temporary coronary occlusion in a canine model Circulation 1996 94:1927-1933 PMID:8873670
- Lefkovits, J., Blankenship, J. C., Anderson, K. M., Stoner, G. L., Talley, J. D., Worley, S. J., Weisman, H. F., Califf, R. M., Topol, E. J. Increased risk of non-q wave myocardial infarction after directional atherectomy is platelet dependent: Evidence from the epic trial Journal of the American College of Cardiology 1996 28:849-855 DOI:10.1016/s0735-1097(96)00239-2 PMID:8837559
- vanderGiessen, W. J., Lincoff, A. M., Schwartz, R. S., vanBeusekom, H. M. M., Serruys, P. W., Holmes, D. R., Ellis, S. G., Topol, E. J. Marked inflammatory sequelae to implantation of biodegradable and nonbiodegradable polymers in porcine coronary arteries Circulation 1996 94:1690-1697 PMID:8840862
- Abdelmeguid, A. E., Topol, E. J., Whitlow, P. L., Sapp, S. K., Ellis, S. G. Significance of mild transient release of creatine kinase-mb fraction after percutaneous coronary interventions Circulation 1996 94:1528-1536 PMID:8840840
- Mak, K. H., Eisenberg, M. J., Plante, S., Strauss, B. H., Arheart, K. L., Topol, E. J. Absence of increased in-hospital complications with reused balloon catheters American Journal of Cardiology 1996 78:717-719 DOI:10.1016/s0002-9149(96)00443-2 PMID:8831419
- Guzman, L. A., Labhasetwar, V., Song, C. X., Jang, Y. S., Lincoff, A. M., Levy, R., Topol, E. J. Local intraluminal infusion of biodegradable polymeric nanoparticles - a novel approach for prolonged drug delivery after balloon angioplasty Circulation 1996 94:1441-1448 PMID:8823004
- Califf, R. M., White, H. D., VandeWerf, E. V., Sadowski, Z., Armstrong, P. W., Vahanian, A., Simoons, M. L., Simes, R. J., Lee, K. L., Topol, E. J. One-year results from the global utilization of streptokinase and tpa for occluded coronary arteries (gusto-i) trial Circulation 1996 94:1233-1238 PMID:8822974
- Topol, E. J., Califf, R., Granger, C., VandeWerf, F., Aylward, P., Simes, J., Col, J., Armstrong, P., Vahanian, A., Neuhaus, K., Rutsch, W., Ardissino, D., et al. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes New England Journal of Medicine 1996 335:775-782 DOI:10.1056/NEJM199609123351103 PMID:8778585
- Pepine, C. J., Holmes, D. R., Block, P. C., Brinker, J. A., Mark, D. B., Mullins, C. E., Nissen, S. E., Topol, E. J., Williams, D. O., Goldberg, S., Hirshfeld, J. W., Serruys, P. W. Coronary artery stents Journal of the American College of Cardiology 1996 28:782-794 PMID:8772772
- Topol, E. J. Early myocardial reperfusion: An assessment of current strategies in acute myocardial infarction European Heart Journal 1996 17:42-48 PMID:11824003
- Holmes, D. R., Garratt, K. N., Isner, J. M., Kearney, M., Berdan, L. G., Schwartz, R. S., Califf, R. M., Topol, E. J. Effect of subintimal resection on initial outcome and restenosis for native coronary lesions and saphenous vein graft disease treated by directional coronary atherectomy - a report from the caveat i and ii investigators Journal of the American College of Cardiology 1996 28:645-651 DOI:10.1016/0735-1097(96)00185-4 PMID:8772751
- Mark, D. B., Talley, J. D., Topol, E. J., Bowman, L., Lam, L. C., Anderson, K. M., Jollis, J. G., Cleman, M. W., Lee, K. L., Aversano, T., Untereker, W. J., DavidsonRay, L., et al. Economic assessment of platelet glycoprotein iib/iiia inhibition for prevention of ischemic complications of high-risk coronary angioplasty Circulation 1996 94:629-635 PMID:8772681
- Peterson, E. D., Hathaway, W. R., Zabel, K. M., Pieper, K. S., Granger, C. B., Wagner, G. S., Topol, E. J., Bates, E. R., Simoons, M. L., Califf, R. M. Prognostic significance of precordial st segment depression during inferior myocardial infarction in the thrombolytic era: Results in 16,521 patients Journal of the American College of Cardiology 1996 28:305-312 DOI:10.1016/0735-1097(96)00133-7 PMID:8800102
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- Newby, L. K., Rutsch, W. R., Califf, R. M., Simoons, M. L., Aylward, P. E., Armstrong, P. W., Woodlief, L. H., Lee, K. L., Topol, E. J., VandeWerf, F. Time from symptom onset to treatment and outcomes after thrombolytic therapy Journal of the American College of Cardiology 1996 27:1646-1655 PMID:8636549
- Lefkovits, J., Ivanhoe, R. J., Califf, R. M., Bergelson, B. A., Anderson, K. M., Stoner, G. L., Weisman, H. F., Topol, E. J. Effects of platelet glycoprotein iib/iiia receptor blockade by a chimeric monoclonal antibody (abciximab) on acute and six-month outcomes after percutaneous transluminal coronary angioplasty for acute myocardial infarction American Journal of Cardiology 1996 77:1045-1051 DOI:10.1016/s0002-9149(96)00128-2 PMID:8644655
- Almony, G. T., Lefkovits, J., Topol, E. J. Antiplatelet and anticoagulant use after myocardial infarction Clinical Cardiology 1996 19:357-365 PMID:8723593
- Langer, A., Goodman, S. G., Topol, E. J., Charlesworth, A., Skene, A. M., Wilcox, R. G., Armstrong, P. W. Late assessment of thrombolytic efficacy (late) study: Prognosis in patients with non-q wave myocardial infarction Journal of the American College of Cardiology 1996 27:1327-1332 DOI:10.1016/0735-1097(96)00012-5 PMID:8626939
- GottsaunerWolf, M., Moliterno, D. J., Lincoff, A. M., Topol, E. J. Restenosis - an open file Clinical Cardiology 1996 19:347-356 PMID:8723592
- Lefkovits, J., Topol, E. J. The clinical role of platelet glycoprotein IIb/IIIa receptor inhibitors in ischemic heart disease Cleveland Clinic Journal of Medicine 1996 63:181-189 PMID:8665658
- Redlitz, A., Nicolini, F. A., Malycky, J. L., Topol, E. J., Plow, E. F. Inducible carboxypeptidase activity - a role in clot lysis in vivo Circulation 1996 93:1328-1330 PMID:8641019
- Barsness, G. W., Ohman, E. M., Califf, R. M., Kereiakes, D. J., George, B. S., Topol, E. J. The thrombolysis and angioplasty in myocardial infarction (tami) trials: A decade of reperfusion strategies Journal of Interventional Cardiology 1996 9:89-115 DOI:10.1111/j.1540-8183.1996.tb00604.x
- Weaver, W. D., White, H. D., Wilcox, R. G., Aylward, P. E., Morris, D., Guerci, A., Ohman, M., Barbash, G. I., Betriu, A., Sadowski, Z., Topol, E. J., Califf, R. M. Comparisons of characteristics and outcomes among women and men with acute myocardial infarction treated with thrombolytic therapy JAMA-Journal of the American Medical Association 1996 275:777-782 DOI:10.1001/jama.275.10.777 PMID:8598594
- Granger, C. B., Hirsh, J., Califf, R. M., Col, J., White, H. D., Betriu, A., Woodlief, L. H., Lee, K. L., Bovill, E. G., Simes, J., Topol, E. J. Activated partial thromboplastin time and outcome after thrombolytic therapy for acute myocardial infarction: Results for the gusto-i trial Circulation 1996 93:870-878 PMID:8598077
- Newby, L. K., Califf, R. M., Guerci, A., Weaver, W. D., Col, J., Horgan, J. H., Mark, D. B., Stebbins, A., VandeWerf, F., Gore, J. M., Topol, E. J. Early discharge in the thrombolytic era: An analysis of criteria for uncomplicated infarction from the global utilization of streptokinase and t-pa for occluded coronary arteries (gusto) trial Journal of the American College of Cardiology 1996 27:625-632 PMID:8606274
- Ellis, S. G., Omoigui, N., Bittl, J. A., Lincoff, M., Wolfe, M. W., Howell, G., Topol, E. J. Analysis and comparison of operator-specific outcomes in interventional cardiology - from a multicenter database of 4860 quality-controlled procedures Circulation 1996 93:431-439 PMID:8565159
- LeBreton, H., Topol, E., Plow, E. F. Evidence for a pivotal role of platelets in vascular reocclusion and restenosis Cardiovascular Research 1996 31:235-236 DOI:10.1016/0008-6363(96)00005-3 PMID:8730399
- Aguirre, F. V., Topol, E. J., Anderson, K. M., Kleiman, N. S., Weisman, H. E., FitzPatrick, S. E., Califf, R. M. Clinical benefit within patient subgroups receiving c7e3 fab (abciximab) during percutaneous coronary revascularization: Subgroup analysis from the epic trial Journal of Invasive Cardiology 1996 8:B21-B29
- Mak, K. H., Eisenberg, M. J., Eccleston, D. S., Brown, K. J., Ellis, S. G., Topol, E. J. Cost-efficacy modeling of catheter reuse for percutaneous transluminal coronary angioplasty Journal of the American College of Cardiology 1996 28:106-111 DOI:10.1016/0735-1097(96)00097-6 PMID:8752801
- Sgarbossa, E. B., Pinski, S. L., Barbagelata, A., Underwood, D. A., Gates, K. B., Topol, E. J., Califf, R. M., Wagner, G. S. Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block New England Journal of Medicine 1996 334:481-487 DOI:10.1056/nejm199602223340801 PMID:8559200
- Metz, B. K., Topol, E. J. Heparin as an adjuvant to thrombolytic therapy in acute myocardial infarction Biomedicine & Pharmacotherapy 1996 50:243-253 DOI:10.1016/0753-3322(96)84821-9 PMID:8952863
- Omoigui, N. A., Miller, D. P., Brown, K. J., Annan, K., Cosgrove, D., Lytle, B., Loop, F., Topol, E. J. Outmigration for coronary bypass surgery in an era of public dissemination of clinical outcomes Circulation 1996 93:27-33 PMID:8616936
- Lefkovits, J., Topol, E. J. Platelet glycoprotein IIb/IIIa receptor antagonists in coronary artery disease European Heart Journal 1996 17:9-18 PMID:8682137
- Nicolini, F. A., Lee, P., Malycky, J. L., Lefkovits, J., KottkeMarchant, K., Plow, E. F., Topol, E. J. Selective inhibition of factor xa during thrombolytic therapy markedly improves coronary artery patency in a canine model of coronary thrombosis Blood Coagulation & Fibrinolysis 1996 7:39-48 DOI:10.1097/00001721-199601000-00005 PMID:8845461
- Muller, D. W. M., Gordon, D., Topol, E. J., Levy, R. J., Golomb, G. Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting American Heart Journal 1996 131:211-218 DOI:10.1016/s0002-8703(96)90343-9 PMID:8579010
- Harrington, R. A., Kleiman, N. S., Kottkemarchant, K., Lincoff, A. M., Tcheng, J. E., Sigmon, K. N., Joseph, D., Rios, G., Trainor, K., Rose, D., Greenberg, C. S., Kitt, M. M., et al. Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein iib/iiia inhibitor during percutaneous coronary intervention American Journal of Cardiology 1995 76:1222-1227 DOI:10.1016/s0002-9149(99)80345-2 PMID:7503000
- Eccleston, D., Topol, E. J. Inhibitors of platelet glycoprotein IIb/IIIa as augmenters of thrombolysis Coronary Artery Disease 1995 6:947-955 PMID:8723017
- Karnash, S. L., Granger, C. B., White, H. D., Woodlief, L. H., Topol, E. J., Califf, R. M. Treating menstruating women with thrombolytic therapy - insights from the global utilization of streptokinase and tissue-plasminogen activator for occluded coronary-arteries (gusto-i) trial Journal of the American College of Cardiology 1995 26:1651-1656 DOI:10.1016/0735-1097(95)00386-x PMID:7594099
- Holmes, D. R., Simpson, J. B., Berdan, L. G., Gottlieb, R. S., Leya, F., Keeler, G. P., Califf, R. M., Topol, E. J. Abrupt closure - the caveat-i experience Journal of the American College of Cardiology 1995 26:1494-1500 DOI:10.1016/0735-1097(95)00339-8 PMID:7594076
- Barbagelata, A., Granger, C. B., Topol, E. J., Worley, S. J., Kereiakes, D. J., George, B. S., Ohman, E. M., Leimberger, J. D., Mark, D. B., Califf, R. M. Frequency, significance, and cost of recurrent ischemia after thrombolytic therapy for acute myocardial-infarction American Journal of Cardiology 1995 76:1007-1013 DOI:10.1016/s0002-9149(99)80285-9 PMID:7484852
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- Gore, J. M., Granger, C. B., Simoons, M. L., Sloan, M. A., Weaver, D., White, H. D., Barbash, G. I., Vandewerf, F., Aylward, P. E., Topol, E. J., Califf, R. M. Stroke after thrombolysis - mortality and functional outcomes in the gusto-i trial Circulation 1995 92:2811-2818 PMID:7586246
- Califf, R. M., Lincoff, A. M., Tcheng, J. E., Topol, E. J. An overview of the results of the EPIC trial European Heart Journal 1995 16:43-49 PMID:8869018
- Barbash, G. I., Reiner, J., White, H. D., Wilcox, R. G., Armstrong, P. W., Sadowski, Z., Morris, D., Aylward, P., Woodlief, L. H., Topol, E. J., Califf, R. M., Ross, A. M. Evaluation of paradoxic beneficial-effects of smoking in patients receiving thrombolytic therapy for acute myocardial-infarction - mechanism of the smokers paradox from the gusto-i trial, with angiographic insights Journal of the American College of Cardiology 1995 26:1222-1229 DOI:10.1016/0735-1097(95)00299-5 PMID:7594035
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- Abdelmeguid, A. E., Whitlow, P. L., Simpfendorfer, C., Sapp, S. K., Franco, I., Ellis, S. G., Topol, E. J. Percutaneous revascularization of ostial saphenous-vein graft stenoses Journal of the American College of Cardiology 1995 26:955-960 DOI:10.1016/0735-1097(95)00266-x PMID:7560623
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- Holmes, D. R., Bates, E. R., Kleiman, N. S., Sadowski, Z., Horgan, J. H. S., Morris, D. C., Califf, R. M., Berger, P. B., Topol, E. J. Contemporary reperfusion therapy for cardiogenic-shock - the gusto-i trial experience Journal of the American College of Cardiology 1995 26:668-674 DOI:10.1016/0735-1097(95)00215-p PMID:7642857
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- Lefkovits, J., Holmes, D. R., Califf, R. M., Safian, R. D., Pieper, K., Keeler, G., Topol, E. J. Predictors and sequelae of distal embolization during saphenous-vein graft intervention from the caveat-ii trial Circulation 1995 92:734-740 PMID:7641351
- Silver, M. J., Sutton, J. M., Hook, S., Lee, P., Malycky, J. L., Phillips, M. L., Ellis, S. G., Topol, E. J., Nicolini, F. A. Adjunctive selectin blockade successfully reduces infarct size beyond thrombolysis in the electrolytic canine coronary-artery model Circulation 1995 92:492-499 PMID:7543381
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- Aguirre, F. V., Topol, E. J., Ferguson, J. J., Anderson, K., Blankenship, J. C., Heuser, R. R., Sigmon, K., Taylor, M., Gottlieb, R., Hanovich, G., Rosenberg, M., Donohue, T. J., et al. Bleeding complications with the chimeric antibody to platelet glycoprotein iib/iiia integrin in patients undergoing percutaneous coronary intervention Circulation 1995 91:2882-2890 PMID:7796496
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- Harrington, R. A., Lincoff, A. M., Califf, R. M., Holmes, D. R., Berdan, L. G., Ohanesian, M. A., Keeler, G. P., Garratt, K. N., Ohman, E. M., Mark, D. B., Jacobs, A. K., Topol, E. J. Characteristics and consequences of myocardial-infarction after percutaneous coronary intervention - insights from the coronary angioplasty versus excisional atherectomy trial (caveat) Journal of the American College of Cardiology 1995 25:1693-1699 DOI:10.1016/0735-1097(95)00091-h PMID:7759725
- Christenson, R. H., Ohman, E. M., Topol, E. J., Ohanesian, M. A., Sigmon, K. N., Duh, S. H., Kereiakes, D., Worley, S. J., George, B. S., Pizzo, C. K., Wall, T. C., Califf, R. M. Creatine-kinase mm and mb isoforms in patients receiving thrombolytic therapy and acute angiography Clinical Chemistry 1995 41:844-852 PMID:7768002
- Holmes, D. R., Califf, R. M., Topol, E. J. Lessons we have learned from the gusto trial Journal of the American College of Cardiology 1995 25:S10-S17 DOI:10.1016/0735-1097(95)90011-x
- Abdelmeguid, A. E., Whitlow, P. L., Sapp, S. K., Ellis, S. G., Topol, E. J. Long-term outcome of transient, uncomplicated in-laboratory coronary artery closure Circulation 1995 91:2733-2741 PMID:7758178
- Smalling, R. W., Bode, C., Kalbfleisch, J., Sen, S., Limbourg, P., Forycki, F., Habib, G., Feldman, R., Hohnloser, S., Seals, A., Califf, R., Guerci, A., et al. More rapid, complete, and stable coronary thrombolysis with bolus administration of reteplase compared with alteplase infusion in acute myocardial infarction Circulation 1995 91:2725-2732 PMID:7758177
- Omoigui, N. A., Topol, E. J. Observational versus randomized medical device testing before and after market approval - the atherectomy-versus-angioplasty controversy Controlled Clinical Trials 1995 16:143-149 DOI:10.1016/0197-2456(95)00035-f PMID:7796597
- Vandewerf, F., Topol, E. J., Lee, K. L., Woodlief, L. H., Granger, C. B., Armstrong, P. W., Barbash, G. I., Hampton, J. R., Guerci, A., Simes, R. J., Ross, A. M., Califf, R. M. Variations in patient-management and outcomes for acute myocardial-infarction in the united-states and other countries - results from the gusto trial JAMA-Journal of the American Medical Association 1995 273:1586-1591 DOI:10.1001/jama.273.20.1586 PMID:7745771
- Boehrer, J. D., Ellis, S. G., Pieper, K., Holmes, D. R., Keeler, G. P., Debowey, D., Chapekis, A. T., Leya, F., Mooney, M. R., Gottlieb, R. S., Serruys, P. W., Califf, R. M., et al. Directional atherectomy versus balloon angioplasty for coronary ostial and nonostial left anterior descending coronary-artery lesions - results from a randomized multicenter trial Journal of the American College of Cardiology 1995 25:1380-1386 DOI:10.1016/0735-1097(95)00008-r PMID:7722137
- Lincoff, A. M., Topol, E. J., Califf, R. M., Sigmon, K. N., Lee, K. L., Ohman, E. M., Rosenschein, U., Ellis, S. G. Significance of a coronary-artery with thrombolysis in myocardial-infarction grade-2 flow patency (outcome in the thrombolysis and angioplasty in myocardial-infarction trials) American Journal of Cardiology 1995 75:871-876 DOI:10.1016/s0002-9149(99)80678-x PMID:7732992
- Tcheng, J. E., Harrington, R. A., Kottkemarchant, K., Kleiman, N. S., Ellis, S. G., Kereiakes, D. J., Mick, M. J., Navetta, F. I., Smith, J. E., Worley, S. J., Miller, J. A., Joseph, D. M., et al. Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein iib/iiia blocker integrelin in elective coronary intervention Circulation 1995 91:2151-2157 PMID:7697843
- Elliott, J. M., Berdan, L. G., Holmes, D. R., Isner, J. M., King, S. B., Keeler, G. P., Kearney, M., Califf, R. M., Topol, E. J. One-year follow-up in the coronary angioplasty versus excisional atherectomy trial (caveat-i) Circulation 1995 91:2158-2166 PMID:7697844
- Pichard, A., Ivanhoe, R., Satler, L., Masden, R., Chapekis, A., Lee, K. L., Reen, B., Levine, G., Abbottsmith, C., Gottlieb, R. S., Stillabower, M., Chambers, J., et al. A multicenter, randomized trial of coronary angioplasty versus directional atherectomy for patients with saphenous vein bypass graft lesions Circulation 1995 91:1966-1974 PMID:7895354
- Becker, R. C., Charlesworth, A., Wilcox, R. G., Hampton, J., Skene, A., Gore, J. M., Topol, E. J. Cardiac rupture associated with thrombolytic therapy - impact of time to treatment in the late assessment of thrombolytic efficacy (late) study Journal of the American College of Cardiology 1995 25:1063-1068 DOI:10.1016/0735-1097(94)00524-t PMID:7897117
- Villa, A. E., Guzman, L. A., Poptic, E. J., Labhasetwar, V., Dsouza, S., Farrell, C. L., Plow, E. F., Levy, R. J., Dicorleto, P. E., Topol, E. J. Effects of antisense c-myb oligonucleotides on vascular smooth-muscle cell-proliferation and response to vessel wall injury Circulation Research 1995 76:505-513 PMID:7895327
- Simes, R. J., Topol, E. J., Holmes, D. R., White, H. D., Rutsch, W. R., Vahanian, A., Simoons, M. L., Morris, D., Betriu, A., Califf, R. M., Ross, A. M. Link between the angiographic substudy and mortality outcomes in a large randomized trial of myocardial reperfusion - importance of early and complete infarct artery reperfusion Circulation 1995 91:1923-1928 PMID:7895348
- Ellis, S. G., Cowley, M. J., Whitlow, P. L., Vandormael, M., Lincoff, A. M., Disciascio, G., Dean, L. S., Topol, E. J. Prospective case-control comparison of percutaneous transluminal coronary revascularization in patients with multivessel disease treated in 1986-1987 versus 1991 - improved in-hospital and 12-month results Journal of the American College of Cardiology 1995 25:1137-1142 DOI:10.1016/0735-1097(94)00541-w PMID:7897127
- Williams, D. O., Baim, D. S., Bates, E., Bonan, R., Bost, J. E., Cowley, M., Faxon, D. P., Feit, F., Jones, R., Kellett, M. A., Kelsey, S. F., Sopko, G., et al. Coronary anatomic and procedural characteristics of patients randomized to coronary angioplasty in the bypass angioplasty revascularization investigation (bari) American Journal of Cardiology 1995 75:C27-C33 DOI:10.1016/s0002-9149(99)80392-0
- Moliterno, D. J., Califf, R. M., Aguirre, F. V., Anderson, K., Sigmon, K. N., Weisman, H. F., Topol, E. J. Effect of platelet glycoprotein iib/iiia integrin blockade on activated clotting time during percutaneous transluminal coronary angioplasty or directional atherectomy (the epic trial) American Journal of Cardiology 1995 75:559-562 DOI:10.1016/s0002-9149(99)80616-x PMID:7887377
- Lee, K. L., Woodlief, L. H., Topol, E. J., Weaver, W. D., Betriu, A., Col, J., Simoons, M., Aylward, P., Vandewerf, F., Califf, R. M. Predictors of 30-day mortality in the era of reperfusion for acute myocardial-infarction - results from an international trial of 41 021 patients Circulation 1995 91:1659-1668 PMID:7882472
- Moliterno, D. J., Elliott, J. M., Topol, E. J. Randomized trials of myocardial revascularization Current Problems in Cardiology 1995 20:128-190 DOI:10.1016/s0146-2806(06)80025-3
- Topol, E. J. Novel antithrombotic approaches to coronary-artery disease American Journal of Cardiology 1995 75:B27-B33 DOI:10.1016/0002-9149(95)80007-f
- Grines, C. L., Topol, E. J., Oneill, W. W., George, B. S., Kereiakes, D., Phillips, H. R., Leimberger, J. D., Woodlief, L. H., Califf, R. M. Effect of cigarette-smoking on outcome after thrombolytic therapy for myocardial-infarction Circulation 1995 91:298-303 PMID:7805231
- Gersh, B. J., Topol, E. J. Angioplasty or thrombolysis in acute myocardial-infarction - dilate or dissolve Cleveland Clinic Journal of Medicine 1995 62:15-19 PMID:7859398
- Mark, D. B., Hlatky, M. A., Califf, R. M., Naylor, C. D., Lee, K. L., Armstrong, P. W., Barbash, G., White, H., Simoons, M. L., Nelson, C. L., Clappchanning, N., Knight, J. D., et al. Cost-effectiveness of thrombolytic therapy with tissue-plasminogen activator as compared with streptokinase for acute myocardial-infarction New England Journal of Medicine 1995 332:1418-1424 DOI:10.1056/nejm199505253322106 PMID:7723799
- Jang, Y. S., Lincoff, A. M., Plow, E. F., Topol, E. J. Cell-adhesion molecules in coronary-artery disease Journal of the American College of Cardiology 1994 24:1591-1601 PMID:7963103
- Boehrer, J. D., Kereiakes, D. J., Navetta, F. I., Califf, R. M., Topol, E. J. Effects of profound platelet inhibition with c7e3 before coronary angioplasty on complications of coronary-bypass survey American Journal of Cardiology 1994 74:1166-1170 DOI:10.1016/0002-9149(94)90474-x PMID:7977081
- Kleiman, N. S., White, H. D., Ohman, E. M., Ross, A. M., Woodlief, L. H., Califf, R. M., Holmes, D. R., Bates, E., Pfisterer, M., Vahanian, A., Topol, E. J. Mortality within 24 hours of thrombolysis for myocardial-infarction - the importance of early reperfusion Circulation 1994 90:2658-2665 PMID:7994805
- Reiner, J. S., Lundergan, C. F., Vandenbrand, M., Boland, J., Thompson, M. A., Machecourt, J., Py, A., Pilcher, G. S., Fink, C. A., Burton, J. R., Simoons, M. L., Califf, R. M., et al. Early angiography cannot predict postthrombolytic coronary reocclusion - observations from the gusto angiographic study Journal of the American College of Cardiology 1994 24:1439-1444 PMID:7930273
- Maclsaac, A. I., Ellis, S. G., Muller, D. W., Topol, E. J., Whitlow, P. L. Comparison of 3 coronary stents - clinical and angiographic outcome after elective placement in 134 consecutive patients Catheterization and Cardiovascular Diagnosis 1994 33:199-204 DOI:10.1002/ccd.1810330302 PMID:7874711
- Savage, M. P., Fischman, D. L., Schatz, R. A., Teirstein, P. S., Leon, M. B., Baim, D., Ellis, S. G., Topol, E. J., Hirshfeld, J. W., Cleman, M. W., Buchbinder, M., Bailey, S., et al. Long-term angiographic and clinical outcome after implantation of a balloon-expandable stent in the native coronary circulation Journal of the American College of Cardiology 1994 24:1207-1212 PMID:7930240
- Ellis, S. G., Dasilva, E. R., Heyndrickx, G., Talley, J. D., Cernigliaro, C., Steg, G., Spaulding, C., Nobuyoshi, M., Erbel, R., Vassanelli, C., Topol, E. J. Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial-infarction Circulation 1994 90:2280-2284 PMID:7955184
- Mark, D. B., Naylor, C. D., Hlatky, M. A., Califf, R. M., Topol, E. J., Granger, C. B., Knight, J. D., Nelson, C. L., Lee, K. L., Clappchanning, N. E., Sutherland, W., Pilote, L., et al. Use of medical resources and quality-of-life after acute myocardial-infarction in canada and the united-states New England Journal of Medicine 1994 331:1130-1135 DOI:10.1056/nejm199410273311706 PMID:7935638
- Lincoff, A. M., Topol, E. J., Ellis, S. G. Local-drug delivery for the prevention of restenosis - fact, fancy, and future Circulation 1994 90:2070-2084 PMID:7923695
- Tcheng, J. E., Ellis, S. G., George, B. S., Kereiakes, D. J., Kleiman, N. S., Talley, J. D., Wang, A. L., Weisman, H. F., Califf, R. M., Topol, E. J. Pharmacodynamics of chimeric glycoprotein iib/iiia integrin antiplatelet antibody fab 7e3 in high-risk coronary angioplasty Circulation 1994 90:1757-1764 PMID:7923659
- Topol, E., Califf, R., Vandewerf, F., Ardissino, D., Armstrong, P., Aylward, P., Barbash, G., Bates, E., Beatt, K., Betriu, A., Chesebro, J., Col, J., et al. Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes Circulation 1994 90:1631-1637 PMID:7923645
- Nissen, S. E., Pepine, C. J., Bashore, T. M., Block, P. C., Bonchek, L. I., Brinker, J. A., Carabello, B., Douglas, J. S., Elion, J. L., Hirshfeld, J. W., Holmes, D. R., Johnson, W. L., et al. Cardiac angiography without cine film - erecting a tower-of-babel in the cardiac-catheterization laboratory Journal of the American College of Cardiology 1994 24:834-837 PMID:8077561
- Lefkovits, J., Topol, E. J. Direct thrombin inhibitors in cardiovascular medicine Circulation 1994 90:1522-1536 PMID:8087958
- Steinberg, J. S., Hochman, J. S., Morgan, C. D., Dorian, P., Naylor, C. D., Theroux, P., Topol, E. J., Armstrong, P. W. Effects of thrombolytic therapy administered 6 to 24 hours after myocardial-infarction on the signal-averaged ecg - results of a multicenter randomized trial Circulation 1994 90:746-752 PMID:8044943
- Faxon, D. P., Spiro, T. E., Minor, S., Cote, G., Douglas, J., Gottlieb, R., Califf, R., Dorosti, K., Topol, E., Gordon, J. B., Ohmen, M., Raizner, A., et al. Low-molecular-weight heparin in prevention of restenosis after angioplasty - results of enoxaparin restenosis (era) trial Circulation 1994 90:908-914 PMID:8044962
- Holmes, D. R., Topol, E. J., Adelman, A. G., Cohen, E. A., Califf, R. M. Randomized trials of directional coronary atherectomy - implications for clinical-practice and future investigation Journal of the American College of Cardiology 1994 24:431-439 PMID:8034880
- Braunwald, E., Jones, R. H., Mark, D. B., Brown, J., Brown, L., Cheitlin, M. D., Concannon, C. A., Cowan, M., Edwards, C., Fuster, V., Goldman, L., Green, L. A., et al. Diagnosing and managing unstable angina Circulation 1994 90:613-622 PMID:8026048
- Wall, T. C., Califf, R. M., Blankenship, J., Talley, J. D., Tannenbaum, M., Schwaiger, M., Gacioch, G., Cohen, M. D., Sanz, M., Leimberger, J. D., Topol, E. J. Intravenous fluosol in the treatment of acute myocardial-infarction - results of the thrombolysis and angioplasty in myocardial-infarction-9 trial Circulation 1994 90:114-120 PMID:8025985
- Brown, D. L., Macisaac, A. I., Topol, E. J. Pulmonary hemorrhage after intracoronary stent placement Journal of the American College of Cardiology 1994 24:91-94 PMID:8006287
- Ellis, S. G., Lincoff, A. M., George, B. S., Kereiakes, D. J., Ohman, E. M., Krucoff, M. W., Califf, R. M., Topol, E. J. Randomized evaluation of coronary angioplasty for early timi-2 flow after thrombolytic therapy for the treatment of acute myocardial-infarction - a new look at an old study Coronary Artery Disease 1994 5:611-615 DOI:10.1097/00019501-199407000-00009 PMID:7952423
- Defranco, A. C., Topol, E. J. Invasive strategies for acute myocardial-infarction in the elderly Cardiology in the Elderly 1994 2:274-289
- Lee, K. L., Califf, R. M., Simes, J., Vandewerf, F., Topol, E. J. Holding gusto up to the light Annals of Internal Medicine 1994 120:876-881 PMID:8154647
- Paranandi, S. N., Topol, E. J. Contemporary clinical-trials of restenosis Journal of Invasive Cardiology 1994 6:109-124 PMID:10147167
- Flaherty, J. T., Pitt, B., Gruber, J. W., Heuser, R. R., Rothbaum, D. A., Burwell, L. R., George, B. S., Kereiakes, D. J., Deitchman, D., Gustafson, N., Brinker, J. A., Becker, L. C., et al. Recombinant human superoxide-dismutase (h-sod) fails to improve recovery of ventricular-function in patients undergoing coronary angioplasty far acute myocardial-infarction Circulation 1994 89:1982-1991 PMID:8181121
- Topol, E. J., Califf, R. M., Weisman, H. F., Ellis, S. G., Tcheng, J. E., Worley, S., Ivanhoe, R., George, B. S., Fintel, D., Weston, M., Sigmon, K., Anderson, K. M., et al. Randomized trial of coronary intervention with antibody against platelet iib/iiia integrin for reduction of clinical restenosis - results at 6 months Lancet 1994 343:881-886 DOI:10.1016/s0140-6736(94)90007-8 PMID:7908357
- Califf, R. M., Shadoff, N., Valett, N., Bates, E., Galeana, A., Knopf, W., Shaftel, J., Bender, M. J., Aversano, T., Raqueno, J., Gurbel, P., Cowfer, J., et al. Use of a monoclonal-antibody directed against the platelet glycoprotein iib/iiia receptor in high-risk coronary angioplasty New England Journal of Medicine 1994 330:956-961 PMID:8121459
- Nicolini, F. A., Lee, P., Rios, G., Kottkemarchant, K., Topol, E. J. Combination of platelet fibrinogen receptor antagonist and direct thrombin inhibitor at low-doses markedly improves thrombolysis Circulation 1994 89:1802-1809 PMID:8149546
- Lefkovits, J., Topol, E. J. Future-directions in thrombolysis for myocardial-infarction - what are the unanswered questions Coronary Artery Disease 1994 5:306-316 DOI:10.1097/00019501-199404000-00006 PMID:8044342
- Topol, E. J., Fuster, V., Harrington, R. A., Califf, R. M., Kleiman, N. S., Kereiakes, D. J., Cohen, M., Chapekis, A., Gold, H. K., Tannenbaum, M. A., Rao, A. K., Debowey, D., et al. Recombinant hirudin for unstable angina-pectoris - a multicenter, randomized angiographic trial Circulation 1994 89:1557-1566 PMID:8149521
- Sgarbossa, E. B., Topol, E. J. Semantic ambiguity, the non-nosology and myocardial-infarction Journal of Clinical Epidemiology 1994 47:441-446 DOI:10.1016/0895-4356(94)90165-1 PMID:7730869
- Harrington, R. A., Sane, D. C., Califf, R. M., Sigmon, K. N., Abbottsmith, C. W., Candela, R. J., Lee, K. L., Topol, E. J. Clinical importance of thrombocytopenia occurring in the hospital phase after administration of thrombolytic therapy for acute myocardial-infarction Journal of the American College of Cardiology 1994 23:891-898 PMID:8106694
- Rosenschein, U., Ellis, S. G., Haudenschild, C. C., Yakubov, S. J., Muller, D. W. M., Dick, R. J., Topol, E. J. Comparison of histopathologic coronary lesions obtained from directional atherectomy in stable angina versus acute coronary syndromes American Journal of Cardiology 1994 73:508-510 DOI:10.1016/0002-9149(94)90683-1 PMID:8141093
- Holmes, D. R., Topol, E. J. Dilate or debulk Cleveland Clinic Journal of Medicine 1994 61:124-126 PMID:8194176
- Villa, A. E., Guzman, L. A., Chen, W. L., Golomb, G., Levy, R. J., Topol, E. J. Local-delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty Journal of Clinical Investigation 1994 93:1243-1249 DOI:10.1172/jci117078 PMID:8132764
- Sutton, J. M., Ellis, S. G., Roubin, G. S., Pinkerton, C. A., King, S. B., Raizner, A. E., Holmes, D. R., Kereiakes, D. J., Topol, E. J. Major clinical events after coronary stenting - the multicenter registry of acute and elective gianturco-roubin stent placement Circulation 1994 89:1126-1137 PMID:8124799
- Hicks, R. J., Melon, P., Kalff, V., Wolfe, E., Dick, R. J., Popma, J. J., Topol, E., Schwaiger, M. Metabolic imaging by positron emission tomography early after myocardial-infarction as a predictor of recovery of myocardial-function after reperfusion Journal of Nuclear Cardiology 1994 1:124-137 DOI:10.1007/bf02984084 PMID:9420679
- Kawai, C., Simoons, M. L., Baigent, C., Lenert, L. A., Collins, R., Lopezsendon, J., Parish, S., Knatterud, G., Visani, L., Halls, H., Nicklas, J., Mead, G., et al. Indications for fibrinolytic therapy in suspected acute myocardial infarction - collaborative overview of early mortality and major morbidity results from all randomized trials of more than 1000 patients Lancet 1994 343:311-322 PMID:7905143
- Vandewerf, F., Santopinto, J., Cordero, F. A., Fainstein, D., Corinaldesi, A., Zavatti, D., Luppi, O., Iparraguirre, H. P., Hirschson, A., Piombo, A., Lapuente, A., Kritzer, J., et al. Randomized trial of ridogrel, a combined thromboxane a(2) synthase inhibitor and thromboxane a(2)/prostaglandin endoperoxide receptor antagonist, versus aspirin as adjunct to thrombolysis in patients with acute myocardial-infarction - the ridogrel versus aspirin patency trial (rapt) Circulation 1994 89:588-595 PMID:8313547
- Ellis, S. G., Popma, J. J., Buchbinder, M., Franco, I., Leon, M. B., Kent, K. M., Pichard, A. D., Satler, L. F., Topol, E. J., Whitlow, P. L. Relation of clinical presentation, stenosis morphology, and operator technique to the procedural results of rotational atherectomy and rotational atherectomy-facilitated angioplasty Circulation 1994 89:882-892 PMID:8313578
- Topol, E. J., Califf, R. M. Scorecard cardiovascular medicine - its impact and future-directions Annals of Internal Medicine 1994 120:65-70 PMID:8250458
- Topol, E. J. Validation of the early open infarct vessel hypothesis American Journal of Cardiology 1993 72:G40-G45 DOI:10.1016/0002-9149(93)90106-m
- Lincoff, A. M., Califf, R. M., Ellis, S. G., Sigmon, K. N., Lee, K. L., Leimberger, J. D., Topol, E. J. Thrombolytic therapy for women with myocardial-infarction - is there a gender-gap Journal of the American College of Cardiology 1993 22:1780-1787 PMID:8245328
- Ross, A. M., Simoons, M. L., Lundergan, C., Thompson, M., Reiner, J., Deychak, Y., Rohrbeck, S., Coyne, K., Walker, P., Cho, S., Greenhouse, S., Lee, K., et al. The effects of tissue-plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular-function, and survival after acute myocardial-infarction New England Journal of Medicine 1993 329:1615-1622 PMID:8232430
- Bernardi, M. M., Califf, R. M., Kleiman, N., Ellis, S. G., Topol, E. J. Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7e3 glycoprotein iib/iiia platelet antibody American Journal of Cardiology 1993 72:1121-1125 DOI:10.1016/0002-9149(93)90979-m PMID:8237799
- Brown, D. L., Topol, E. J. Stroke complicating percutaneous coronary revascularization American Journal of Cardiology 1993 72:1207-1209 DOI:10.1016/0002-9149(93)90998-r PMID:8237818
- Ohman, E. M., Topol, E. J., Califf, R. M., Bates, E. R., Ellis, S. G., Kereiakes, D. J., George, B. S., Samaha, J. K., Kline, E., Sigmon, K. N., Stack, R. S. An analysis of the cause of early mortality after administration of thrombolytic therapy Coronary Artery Disease 1993 4:957-964 DOI:10.1097/00019501-199311000-00002 PMID:8173712
- Topol, E. J. Breaking the thrombolytic gridlock - insights from the gusto trial Cleveland Clinic Journal of Medicine 1993 60:445-447 PMID:8287504
- Nath, F. C., Muller, D. W. M., Rosenschein, U., Ellis, S. G., Topol, E. J. Heparin monitoring during coronary intervention - activated clotting time versus activated partial thromboplastin time Canadian Journal of Cardiology 1993 9:797-801 PMID:8281479
- Cowley, M. J., Vandermael, M., Topol, E. J., Whitlow, P. L., Dean, L. S., Bulle, T. M., Ellis, S. G. Is traditionally defined complete revascularization needed for patients with multivessel disease treated by elective coronary angioplasty Journal of the American College of Cardiology 1993 22:1289-1297 PMID:8227782
- Baim, D. S., Hinohara, T., Holmes, D., Topol, E., Pinkerton, C., King, S. B., Whitlow, P., Kereiakes, D., Farley, B., Simpson, J. B. Results of directional coronary atherectomy during multicenter preapproval testing American Journal of Cardiology 1993 72:6E-11E DOI:10.1016/0002-9149(93)91032-d PMID:8213572
- Ohman, E. M., Christenson, R. H., Califf, R. M., George, B. S., Samaha, J. K., Kereiakes, D. J., Worley, S. J., Wall, T. C., Berrios, E., Sigmon, K. N., Lee, K., Topol, E. J. Noninvasive detection of reperfusion after thrombolysis based on serum creatine-kinase mb changes and clinical-variables American Heart Journal 1993 126:819-826 DOI:10.1016/0002-8703(93)90694-5 PMID:8213437
- Macisaac, A. I., Thomas, J. D., Topol, E. J. Toward the quiescent coronary plaque Journal of the American College of Cardiology 1993 22:1228-1241 PMID:8104965
- Hampton, J., Wilcox, R., Armstrong, P., Aylward, P., Bett, N., Charbonnier, B., Gulba, D., Heikkila, J., Jensen, G., Lopezbescos, L., Moulopoulos, S., Seabragomes, R., et al. Late assessment of thrombolytic efficacy (late) study with alteplase 6-24 hours after onset of acute myocardial-infarction Lancet 1993 342:759-766 PMID:8103874
- Topol, E., Califf, R., Vandewerf, F., Armstrong, P. W., Aylward, P., Barbash, G., Bates, E., Betriu, A., Boissel, J. P., Chesebro, J., Col, J., Debono, D., et al. An international randomized trial comparing 4 thrombolytic strategies for acute myocardial-infarction New England Journal of Medicine 1993 329:673-682 PMID:8204123
- Krucoff, M. W., Croll, M. A., Pope, J. E., Granger, C. B., Oconnor, C. M., Sigmon, K. N., Wagner, B. L., Ryan, J. A., Lee, K. L., Kereiakes, D. J., Samaha, J. K., Worley, S. J., et al. Continuous 12-lead st-segment recovery analysis in the tami 7 study - performance of a noninvasive method for real-time detection of failed myocardial reperfusion Circulation 1993 88:437-446 PMID:8339407
- Topol, E. J., Leya, F., Pinkerton, C. A., Whitlow, P. L., Hofling, B., Simonton, C. A., Masden, R. R., Serruys, P. W., Leon, M. B., Williams, D. O., King, S. B., Mark, D. B., et al. A comparison of directional atherectomy with coronary angioplasty in patients with coronary-artery disease New England Journal of Medicine 1993 329:221-227 DOI:10.1056/nejm199307223290401 PMID:8316266
- Topol, E. J., Plow, E. F. Clinical-trials of platelet receptor inhibitors Thrombosis and Haemostasis 1993 70:94-98 PMID:8236122
- George, B. S., Voorhees, W. D., Roubin, G. S., Fearnot, N. E., Pinkerton, C. A., Raizner, A. E., King, S. B., Holmes, D. R., Topol, E. J., Kereiakes, D. J., Hartzler, G. O. Multicenter investigation of coronary stenting to treat acute or threatened closure after percutaneous transluminal coronary angioplasty - clinical and angiographic outcomes Journal of the American College of Cardiology 1993 22:135-143 PMID:8509533
- Defeyter, Pimj, Vansuylen, R. J., Dejaegere, P. P. T., Topol, E. J., Serruys, P. W. Balloon angioplasty for the treatment of lesions in saphenous-vein bypass grafts Journal of the American College of Cardiology 1993 21:1539-1549 PMID:8496517
- Casale, P. N., Whitlow, P. L., Franco, I., Grigera, F., Pashkow, F. J., Topol, E. J. Comparison of major complication rates with new atherectomy devices for percutaneous coronary intervention in women versus men American Journal of Cardiology 1993 71:1221-1223 DOI:10.1016/0002-9149(93)90650-2 PMID:8480650
- Topol, E. J., Ellis, S. G., Cosgrove, D. M., Bates, E. R., Muller, D. W. M., Schork, N. J., Schork, M. A., Loop, F. D. Analysis of coronary angioplasty practice in the united-states with an insurance-claims data-base Circulation 1993 87:1489-1497 PMID:8141866
- Lee, K. S., Topol, E. J., Stewart, W. J. Atypical presentation of papillary fibroelastoma mimicking multiple vegetations in suspected subacute bacterial-endocarditis American Heart Journal 1993 125:1443-1445 DOI:10.1016/0002-8703(93)91025-a PMID:8480605
- Harrison, J. K., Califf, R. M., Woodlief, L. H., Kereiakes, D., George, B. S., Stack, R. S., Ellis, S. G., Lee, K. L., Oneill, W., Topol, E. J. Systolic left-ventricular function after reperfusion therapy for acute myocardial-infarction - an analysis of determinants of improvement Circulation 1993 87:1531-1541 PMID:8491008
- Topol, E. J., Bonan, R., Jewitt, D., Sigwart, U., Kakkar, V. V., Rothman, M., Debono, D., Ferguson, J., Willerson, J. T., Strony, J., Ganz, P., Cohen, M. D., et al. Use of a direct antithrombin, hirulog, in place of heparin during coronary angioplasty Circulation 1993 87:1622-1629 PMID:8491018
- Chapman, G. D., Ohman, M., Topol, E. J., Candela, R. J., Kereiakes, D. J., Samaha, J., Berrios, E., Pieper, K. S., Young, S. Y., Califf, R. M. Minimizing the risk of inappropriately administering thrombolytic therapy (thrombolysis and angioplasty in myocardial-infarction tami study-group) American Journal of Cardiology 1993 71:783-787 DOI:10.1016/0002-9149(93)90824-v PMID:8456754
- Lincoff, A. M., Topol, E. J., Chapekis, A. T., George, B. S., Candela, R. J., Muller, D. W. M., Zimmerman, C. A., Ellis, S. G. Intracoronary stenting compared with conventional therapy for abrupt vessel closure complicating coronary angioplasty - a matched case-control study Journal of the American College of Cardiology 1993 21:866-875 PMID:8450155
- Granger, C. B., Califf, R. M., Young, S., Candela, R., Samaha, J., Worley, S., Kereiakes, D. J., Topol, E. J. Outcome of patients with diabetes-mellitus and acute myocardial-infarction treated with thrombolytic agents Journal of the American College of Cardiology 1993 21:920-925 PMID:8450161
- Sane, D. C., Califf, R. M., Sigmon, K. N., Topol, E. J., Stump, D. C. Effect of heparin administration on fibrinogenolysis during thrombolytic therapy with tissue plasminogen activator for acute myocardial infarction Fibrinolysis 1993 7:103-107 DOI:10.1016/0268-9499(93)90030-y
- Wall, T. C., Califf, R. M., Ellis, S. G., Sigmon, K., Kereiakes, D., George, B. S., Samaha, J., Sane, D., Stump, D. C., Stack, R. S., Topol, E. J. Lack of impact of early catheterization and fibrin specificity on bleeding complications after thrombolytic therapy Journal of the American College of Cardiology 1993 21:597-603 PMID:8436740
- Popma, J. J., Decesare, N. B., Pinkerton, C. A., Kereiakes, D. J., Whitlow, P., King, S. B., Topol, E. J., Holmes, D. R., Leon, M. B., Ellis, S. G. Quantitative-analysis of factors influencing late lumen loss and restenosis after directional coronary atherectomy American Journal of Cardiology 1993 71:552-557 DOI:10.1016/0002-9149(93)90510-j PMID:8438740
- Nath, F. C., Muller, D. W. M., Ellis, S. G., Rosenschein, U., Chapekis, A., Quain, L., Zimmerman, C., Topol, E. J. Thrombosis of a flexible coil coronary stent - frequency, predictors and clinical outcome Journal of the American College of Cardiology 1993 21:622-627 PMID:8436743
- Kalff, V., Hicks, R. J., Hutchins, G., Topol, E., Schwaiger, M. Use of c-11 acetate and dynamic positron emission tomography to assess regional myocardial oxygen-consumption in patients with acute myocardial-infarction receiving thrombolysis or coronary angioplasty American Journal of Cardiology 1993 71:529-535 DOI:10.1016/0002-9149(93)90507-9 PMID:8438738
- Ellis, S. G., Tcheng, J. E., Navetta, F. I., Muller, D. W. M., Weisman, H. F., Smith, C., Anderson, K. M., Califf, R. M., Topol, E. J. Safety and antiplatelet effect of murine monoclonal-antibody 7e3 fab directed against platelet glycoprotein-iib/iiia in patients undergoing elective coronary angioplasty Coronary Artery Disease 1993 4:167-175 DOI:10.1097/00019501-199302000-00007 PMID:8269208
- Lincoff, A. M., Topol, E. J. Illusion of reperfusion. Does anyone achieve optimal reperfusion during acute myocardial infarction? Circulation 1993 87:1792-1805 PMID:8353902
- Doorey, A. J., Michelson, E. L., Topol, E. J. Thrombolytic therapy of acute myocardial-infarction - keeping the unfulfilled promises JAMA-Journal of the American Medical Association 1992 268:3108-3114 DOI:10.1001/jama.268.21.3108 PMID:1433742
- Sutton, J. M., Topol, E. J. Left ventricular function assessment and acute myocardial infarction Current Opinion in Cardiology 1992 7:1035-1045 DOI:10.1097/00001573-199212000-00016
- Ellis, S. G., Savage, M., Fischman, D., Baim, D. S., Leon, M., Goldberg, S., Hirshfeld, J. W., Cleman, M. W., Teirstein, P. S., Walker, C., Bailey, S., Buchbinder, M., et al. Restenosis after placement of palmaz-schatz stents in native coronary-arteries - initial results of a multicenter experience Circulation 1992 86:1836-1844 PMID:1451256
- Popma, J. J., Califf, R. M., Ellis, S. G., George, B. S., Kereiakes, D. J., Samaha, J. K., Worley, S. J., Anderson, J. L., Stump, D., Woodlief, L., Sigmon, K., Wall, T. C., et al. Mechanism of benefit of combination thrombolytic therapy for acute myocardial-infarction - a quantitative angiographic and hematologic study Journal of the American College of Cardiology 1992 20:1305-1312 PMID:1430679
- Rosenschein, U., Yakubov, S. J., Guberinich, D., Bach, D. S., Sonda, P. L., Abrams, G. D., Topol, E. J. Shock-wave thrombus ablation, a new method for noninvasive mechanical thrombolysis American Journal of Cardiology 1992 70:1358-1361 DOI:10.1016/0002-9149(92)90775-t PMID:1442591
- Ellis, S. G., Mooney, M. R., George, B. S., Dasilva, E. E. R., Talley, J. D., Flanagan, W. H., Topol, E. J., Griffin, B., Samaha, J., Sawicki, E., Mooney, J., Chapekis, A. T., et al. Randomized trial of late elective angioplasty versus conservative management for patients with residual stenoses after thrombolytic treatment of myocardial-infarction Circulation 1992 86:1400-1406 PMID:1423952
- Williamson, B. D., Muller, D. W. M., Topol, E. J. Should older patients with acute myocardial-infarction receive thrombolytic therapy Drugs & Aging 1992 2:461-468 PMID:1493350
- Schwartz, R. S., Holmes, D. R., Topol, E. J. The restenosis paradigm revisited - an alternative proposal for cellular mechanisms Journal of the American College of Cardiology 1992 20:1284-1293 PMID:1401633
- Rosenschein, U., Ellis, S. G., Yakubov, S. J., Haudenschild, C. C., Dick, R. J., Topol, E. J. Histopathologic correlates of coronary lesion angiographic morphology - lessons from a directional atherectomy experience Coronary Artery Disease 1992 3:953-961
- Grambow, D. W., Topol, E. J. Effect of maximal medical therapy on refractoriness of unstable angina-pectoris American Journal of Cardiology 1992 70:577-581 DOI:10.1016/0002-9149(92)90194-4 PMID:1354937
- Granger, C. B., Califf, R. M., Topol, E. J. Thrombolytic therapy for acute myocardial-infarction - a review Drugs 1992 44:293-325 DOI:10.2165/00003495-199244030-00002 PMID:1382931
- Arnold, A. Z., Topol, E. J. Assessment of reperfusion after thrombolytic therapy for myocardial-infarction American Heart Journal 1992 124:441-447 DOI:10.1016/0002-8703(92)90611-x PMID:1636587
- Muller, D. W. M., Topol, E. J., Abrams, G. D., Gallagher, K. P., Ellis, S. G. Intramural methotrexate therapy for the prevention of neointimal thickening after balloon angioplasty Journal of the American College of Cardiology 1992 20:460-466 PMID:1386089
- Topol, E. J., Califf, R. M., Vandormael, M., Grines, C. L., George, B. S., Sanz, M. L., Wall, T., Obrien, M., Schwaiger, M., Aguirre, F. V., Young, S., Popma, J. J., et al. A randomized trial of late reperfusion therapy for acute myocardial infarction Circulation 1992 85:2090-2099 PMID:1591828
- Popma, J. J., Topol, E. J., Hinohara, T., Pinkerton, C. A., Baim, D. S., King, S. B., Holmes, D. R., Whitlow, P. L., Kereiakes, D. J., Hartzler, G. O., Kent, K. M., Ellis, S. G., et al. Abrupt vessel closure after directional coronary atherectomy Journal of the American College of Cardiology 1992 19:1372-1379 PMID:1593028
- Topol, E. J., Armstrong, P., Vandewerf, F., Kleiman, N., Lee, K., Morris, D., Simoons, M., Barbash, G., White, H., Califf, R. M. Confronting the issues of patient safety and investigator conflict-of-interest in an international clinical-trial of myocardial reperfusion Journal of the American College of Cardiology 1992 19:1123-1128 PMID:1564212
- Lincofe, A. M., Popma, J. J., Ellis, S. G., Hacker, J. A., Topol, E. J. Abrupt vessel closure complicating coronary angioplasty - clinical, angiographic and therapeutic profile Journal of the American College of Cardiology 1992 19:926-935 PMID:1552113
- Wall, T. C., Califf, R. M., George, B. S., Ellis, S. G., Samaha, J. K., Kereiakes, D. J., Worley, S. J., Sigmon, K., Topol, E. J. Accelerated plasminogen-activator dose regimens for coronary thrombolysis Journal of the American College of Cardiology 1992 19:482-489 PMID:1537998
- Gacioch, G. M., Ellis, S. G., Lee, L., Bates, E. R., Kirsh, M., Walton, J. A., Topol, E. J. Cardiogenic-shock complicating acute myocardial-infarction - the use of coronary angioplasty and the integration of the new support devices into patient-management Journal of the American College of Cardiology 1992 19:647-653 PMID:1538023
- Decesare, N. B., Popma, J. J., Holmes, D. R., Dick, R. J., Whitlow, P. L., King, S. B., Pinkerton, C. A., Kereiakes, D. J., Topol, E. J., Haudenschild, C. C., Ellis, S. G. Clinical angiographic and histologic correlates of ectasia after directional coronary atherectomy American Journal of Cardiology 1992 69:314-319 DOI:10.1016/0002-9149(92)90226-o PMID:1734641
- Muller, D. W. M., Ellis, S. G., Topol, E. J. Experimental-models of coronary-artery restenosis Journal of the American College of Cardiology 1992 19:418-432 PMID:1732371
- Muller, D. W. M., Topol, E. J. Thrombolytic therapy - adjuvant mechanical intervention for acute myocardial-infarction American Journal of Cardiology 1992 69:A60-A70 DOI:10.1016/0002-9149(92)91172-z
- Muller, D. W. M., Shamir, K. J., Ellis, S. G., Topol, E. J. Peripheral vascular complications after conventional and complex percutaneous coronary interventional procedures American Journal of Cardiology 1992 69:63-68 DOI:10.1016/0002-9149(92)90677-q PMID:1729869
- Kirshenbaum, J. M., Bahr, R. D., Flaherty, J. T., Gurewich, V., Levine, H. J., Loscalzo, J., Schumacher, R. R., Topol, E. J., Wahr, D. W., Braunwald, E. Clot-selective coronary thrombolysis with low-dose synergistic combinations of single-chain urokinase-type plasminogen-activator and recombinant tissue-type plasminogen-activator American Journal of Cardiology 1991 68:1564-1569 DOI:10.1016/0002-9149(91)90310-h PMID:1746455
- Ellis, S. G., Myler, R. K., King, S. B., Douglas, J. S., Topol, E. J., Shaw, R. E., Stertzer, S. H., Roubin, G. S., Murphy, M. C. Causes and correlates of death after unsupported coronary angioplasty - implications for use of angioplasty and advanced support techniques in high-risk settings American Journal of Cardiology 1991 68:1447-1451 DOI:10.1016/0002-9149(91)90277-r PMID:1746425
- Muller, D. W. M., Topol, E. J., Ellis, S. G., Woodlief, L. H., Sigmon, K. N., Kereiakes, D. J., George, B. S., Worley, S. J., Samaha, J. K., Phillips, H., Califf, R. M. Determinants of the need for early acute intervention in patients treated conservatively after thrombolytic therapy for acute myocardial-infarction Journal of the American College of Cardiology 1991 18:1594-1601 PMID:1960302
- Popma, J. J., Decesare, N. B., Ellis, S. G., Holmes, D. R., Pinkerton, C. A., Whitlow, P., King, S. B., Ghazzal, Z. M. B., Topol, E. J., Garratt, K. N., Kereiakes, D. J. Clinical, angiographic and procedural correlates of quantitative coronary dimensions after directional coronary atherectomy Journal of the American College of Cardiology 1991 18:1183-1189 PMID:1918694
- Topol, E. J. Which thrombolytic agent should one choose Progress in Cardiovascular Diseases 1991 34:165-178 DOI:10.1016/0033-0620(91)90011-a PMID:1947122
- Tenaglia, A. N., Califf, R. M., Candela, R. J., Kereiakes, D. J., Berrios, E., Young, S. Y., Stack, R. S., Topol, E. J. Thrombolytic therapy in patients requiring cardiopulmonary-resuscitation American Journal of Cardiology 1991 68:1015-1019 DOI:10.1016/0002-9149(91)90488-7 PMID:1927913
- Lee, P. N. V., Muller, D. W. M., Popma, J. J., Ellis, S. G., Topol, E. J. A comparison of clinical and quantitative angiographic outcomes of coronary stenting in elective and emergency settings: a single center experience Coronary Artery Disease 1991 2:945-951
- Dellborg, M., Topol, E. J., Swedberg, K. Dynamic qrs complex and st segment vectorcardiographic monitoring can identify vessel patency in patients with acute myocardial-infarction treated with reperfusion therapy American Heart Journal 1991 122:943-948 DOI:10.1016/0002-8703(91)90455-q PMID:1927880
- Dick, R. J., Popma, J. J., Muller, D. W. M., Burek, K. A., Topol, E. J. In-hospital costs associated with new percutaneous coronary devices American Journal of Cardiology 1991 68:879-885 DOI:10.1016/0002-9149(91)90403-8 PMID:1927947
- Bates, E. R., Topol, E. J. Limitations of thrombolytic therapy for acute myocardial-infarction complicated by congestive-heart-failure and cardiogenic-shock Journal of the American College of Cardiology 1991 18:1077-1084 PMID:1894853
- Topol, E. J. Integration of anticoagulation, thrombolysis and coronary angioplasty for unstable angina-pectoris American Journal of Cardiology 1991 68:B136-B141 DOI:10.1016/0002-9149(91)90396-3
- Muller, D. W. M., Topol, E. J. Implantable devices in the coronary-artery - from metal to genes Trends in Cardiovascular Medicine 1991 1:225-232 DOI:10.1016/1050-1738(91)90026-b PMID:21239300
- Morris, J. A., Muller, D. W. M., Topol, E. J. Combination thrombolytic therapy - a comparison of simultaneous and sequential regimens of tissue plasminogen-activator and urokinase American Heart Journal 1991 122:375-380 DOI:10.1016/0002-8703(91)90988-t PMID:1907086
- Kereiakes, D. J., Califf, R. M., George, B. S., Ellis, S., Samaha, J., Stack, R., Martin, L. H., Young, S., Topol, E. J. Coronary-bypass surgery improves global and regional left-ventricular function following thrombolytic therapy for acute myocardial-infarction American Heart Journal 1991 122:390-399 DOI:10.1016/0002-8703(91)90991-p PMID:1907087
- Ellis, S. G., Decesare, N. B., Pinkerton, C. A., Whitlow, P., King, S. B., Ghazzal, Z. M. B., Kereiakes, D. J., Popma, J. J., Menke, K. K., Topol, E. J., Holmes, D. R. Relation of stenosis morphology and clinical presentation to the procedural results of directional coronary atherectomy Circulation 1991 84:644-653 PMID:1860208
- Popma, J. J., Topol, E. J. Adjuncts to thrombolysis for myocardial reperfusion Annals of Internal Medicine 1991 115:34-44 PMID:1675557
- Ellis, S. G., Cowley, M. J., Disciascio, G., Deligonul, U., Topol, E. J., Bulle, T. M., Vandormael, M. G. Determinants of 2-year outcome after coronary angioplasty in patients with multivessel disease on the basis of comprehensive preprocedural evaluation - implications for patient selection Circulation 1991 83:1905-1914 PMID:2040043
- Topol, E. J., Holmes, D. R., Rogers, W. J. Coronary angiography after thrombolytic therapy for acute myocardial-infarction Annals of Internal Medicine 1991 114:877-885 PMID:2014950
- Schatz, R. A., Goldberg, S., Leon, M., Baim, D., Hirshfeld, J., Cleman, M., Ellis, S., Topol, E. Clinical-experience with the palmaz-schatz coronary stent Journal of the American College of Cardiology 1991 17:B155-B159
- Muller, D. W. M., Ellis, S. G., Topol, E. J. Colchicine and antineoplastic therapy for the prevention of restenosis after percutaneous coronary interventions Journal of the American College of Cardiology 1991 17:B126-B131
- Califf, R. M., Topol, E. J., Stack, R. S., Ellis, S. G., George, B. S., Kereiakes, D. J., Samaha, J. K., Worley, S. J., Anderson, J. L., Harrelson-Woodlief, S. L., Wall, T. C., Phillips, H. R., et al. Evaluation of combination thrombolytic therapy and timing of cardiac-catheterization in acute myocardial-infarction - results of thrombolysis and angioplasty in myocardial-infarction phase-5 randomized trial Circulation 1991 83:1543-1556 PMID:1902405
- Ellis, S. G., Bates, E. R., Schaible, T., Weisman, H. F., Pitt, B., Topol, E. J. Prospects for the use of antagonists to the platelet glycoprotein-IIb glycoprotein-IIIa receptor to prevent postangioplasty restenosis and thrombosis Journal of the American College of Cardiology 1991 17:B89-B95
- Dick, R. J. L., Haudenschild, C. C., Popma, J. J., Ellis, S. G., Muller, D. W., Topol, E. J. Directional atherectomy for total coronary occlusions Coronary Artery Disease 1991 2:189-199 DOI:10.1097/00019501-199104000-00010
- Mark, D. B., Sigmon, K., Topol, E. J., Kereiakes, D. J., Pryor, D. B., Candela, R. J., Califf, R. M. Identification of acute myocardial-infarction patients suitable for early hospital discharge after aggressive interventional therapy - results from the thrombolysis and angioplasty in acute myocardial-infarction registry Circulation 1991 83:1186-1193 PMID:2013140
- Muller, D. W. M., Topol, E. J., Ellis, S. G., Sigmon, K. N., Lee, K., Califf, R. M. Multivessel coronary-artery disease - a key predictor of short-term prognosis after reperfusion therapy for acute myocardial-infarction American Heart Journal 1991 121:1042-1049 DOI:10.1016/0002-8703(91)90661-z PMID:1901190
- Sutton, J. M., Topol, E. J. Significance of a negative exercise thallium test in the presence of a critical residual stenosis after thrombolysis for acute myocardial-infarction Circulation 1991 83:1278-1286 PMID:1901529
- Topol, E. J., Agnelli, G. Strategies for administration of tissue plasminogen-activator Molecular Biology & Medicine 1991 8:219-234 PMID:1806764
- Stewart, R. E., Kander, N., Juni, J. E., Ellis, S. G., Oneill, W. W., Schork, A., Topol, E. J., Schwaiger, M. Submaximal exercise tl-201 spect for assessment of interventional therapy in patients with acute myocardial-infarction American Heart Journal 1991 121:1033-1041 DOI:10.1016/0002-8703(91)90660-a PMID:1901189
- Sane, D. C., Stump, D. C., Topol, E. J., Sigmon, K. N., Kereiakes, D. J., George, B. S., Mantell, S. J., Macy, E., Collen, D., Califf, R. M. Correlation between base-line plasminogen-activator inhibitor levels and clinical outcome during therapy with tissue plasminogen-activator for acute myocardial-infarction Thrombosis and Haemostasis 1991 65:275-279 PMID:1904653
- Lincoff, A. M., Popma, J. J., Ellis, S. G., Vogel, R. A., Topol, E. J. Percutaneous support devices for high-risk or complicated coronary angioplasty Journal of the American College of Cardiology 1991 17:770-780 PMID:1993799
- Ohman, E. M., Califf, R. M., George, B. S., Quigley, P. J., Kereiakes, D. J., Harrelson-Woodlief, S. L., Candela, R. J., Flanagan, C., Stack, R. S., Topol, E. J. The use of intraaortic balloon pumping as an adjunct to reperfusion therapy in acute myocardial-infarction American Heart Journal 1991 121:895-901 DOI:10.1016/0002-8703(91)90205-v PMID:1900381
- Ellis, S. G., Debowey, D., Bates, E. R., Topol, E. J. Treatment of recurrent ischemia after thrombolysis and successful reperfusion for acute myocardial-infarction - effect on in-hospital mortality and left-ventricular function Journal of the American College of Cardiology 1991 17:752-757 PMID:1993797
- Popma, J. J., Dick, R. J. L., Haudenschild, C. C., Topol, E. J., Ellis, S. G. Atherectomy of right coronary ostial stenoses - initial and long-term results, technical features and histologic-findings American Journal of Cardiology 1991 67:431-434 DOI:10.1016/0002-9149(91)90057-r PMID:1994670
- Nabel, E. G., Topol, E. J., Galeana, A., Ellis, S. G., Bates, E. R., Werns, S. W., Walton, J. A., Muller, D. W., Schwaiger, M., Pitt, B. A randomized placebo-controlled trial of combined early intravenous captopril and recombinant tissue-type plasminogen-activator therapy in acute myocardial-infarction Journal of the American College of Cardiology 1991 17:467-473 PMID:1825097
- Clemmensen, P., Bates, E. R., Califf, R. M., Hlatky, M. A., Aronson, L., George, B. S., Lee, K. L., Kereiakes, D. J., Gacioch, G., Berrios, E., Topol, E. J. Complete atrioventricular-block complicating inferior wall acute myocardial-infarction treated with reperfusion therapy American Journal of Cardiology 1991 67:225-230 DOI:10.1016/0002-9149(91)90550-5 PMID:1899319
- Kereiakes, D. J., Topol, E. J., George, B. S., Stack, R. S., Abbottsmith, C. W., Ellis, S., Candela, R. J., Harrelson, L., Martin, L. H., Califf, R. M. Myocardial-infarction with minimal coronary atherosclerosis in the era of thrombolytic reperfusion Journal of the American College of Cardiology 1991 17:304-312 PMID:1899433
- Schatz, R. A., Baim, D. S., Leon, M., Ellis, S. G., Goldberg, S., Hirshfeld, J. W., Cleman, M. W., Cabin, H. S., Walker, C., Stagg, J., Buchbinder, M., Teirstein, P. S., et al. Clinical-experience with the palmaz-schatz coronary stent - initial results of a multicenter study Circulation 1991 83:148-161 PMID:1984878
- Sane, D. C., Stump, D. C., Topol, E. J., Sigmon, K. N., Clair, W. K., Kereiakes, D. J., George, B. S., Stoddard, M. F., Bates, E. R., Stack, R. S., Califf, R. M. Racial-differences in responses to thrombolytic therapy with recombinant tissue-type plasminogen-activator - increased fibrin(ogen)olysis in blacks Circulation 1991 83:170-175 PMID:1898641
- Muller, D. W. M., Topol, E. J. Selection of patients with acute myocardial-infarction for thrombolytic therapy Annals of Internal Medicine 1990 113:949-960 PMID:2240919
- Wall, T. C., Califf, R. M., Harrelson-Woodlief, S. L. ,, Mark, D. B., Honan, M., Abbotsmith, C. W., Candela, R., Berrios, E., Phillips, H. R., Topol, E. J. Usefulness of a pericardial friction rub after thrombolytic therapy during acute myocardial-infarction in predicting amount of myocardial damage American Journal of Cardiology 1990 66:1418-1421 DOI:10.1016/0002-9149(90)90526-7 PMID:2123603
- Bates, E. R., Clemmensen, P. M., Califf, R. M., Gorman, L. E., Aronson, L. G., George, B. S., Kereiakes, D. J., Topol, E. J. Precordial st segment depression predicts a worse prognosis in inferior infarction despite reperfusion therapy Journal of the American College of Cardiology 1990 16:1538-1544 PMID:2123903
- Topol, E. J. Can thrombolysis be improved? Hospital Formulary 1990 25:19-22
- Topol, E. J., Wilson, V. E. Pivotal role of early and sustained infarct vessel patency in patients with acute myocardial-infarction Heart & Lung 1990 19:583-595 PMID:2228647
- Muller, D. W. M., Ellis, S. G., Debowey, D. L., Topol, E. J. Quantitative angiographic comparison of the immediate success of coronary angioplasty, coronary atherectomy and endoluminal stenting American Journal of Cardiology 1990 66:938-942 DOI:10.1016/0002-9149(90)90929-u PMID:2220616
- Ellis, S. G., Topol, E. J. Results of percutaneous transluminal coronary angioplasty of high-risk angulated stenoses American Journal of Cardiology 1990 66:932-937 DOI:10.1016/0002-9149(90)90928-t PMID:2220615
- Muller, D. W. M., Topol, E. J., George, B. S., Kereiakes, D. J., Aronson, L. G., Lee, K. L., Abbottsmith, C. W., Ellis, S. G., Califf, R. M. 2-year outcome after angiographically documented myocardial reperfusion for acute coronary-occlusion American Journal of Cardiology 1990 66:796-801 DOI:10.1016/0002-9149(90)90354-4 PMID:2220575
- Ellis, S. G., Vandormael, M. G., Cowley, M. J., Disciascio, G., Deligonul, U., Topol, E. J., Bulle, T. M. Coronary morphological and clinical determinants of procedural outcome with angioplasty for multivessel coronary-disease - implications for patient selection Circulation 1990 82:1193-1202 PMID:2401060
- Abbottsmith, C. W., Topol, E. J., George, B. S., Stack, R. S., Kereiakes, D. J., Candela, R. J., Anderson, L. C., Harrelson-Woodlief, S. L. ,, Califf, R. M. Fate of patients with acute myocardial-infarction with patency of the infarct-related vessel achieved with successful thrombolysis versus rescue angioplasty Journal of the American College of Cardiology 1990 16:770-778 PMID:1698843
- Ohman, E. M., Califf, R. M., Topol, E. J., Candela, R., Abbottsmith, C., Ellis, S., Sigmon, K. N., Kereiakes, D., George, B., Stack, R. Consequences of reocclusion after successful reperfusion therapy in acute myocardial-infarction Circulation 1990 82:781-791 PMID:2394002
- Oconnor, C. M., Califf, R. M., Massey, E. W., Mark, D. B., Kereiakes, D. J., Candela, R. J., Abbottsmith, C., George, B., Stack, R. S., Aronson, L., Mantell, S., Topol, E. J. Stroke and acute myocardial-infarction in the thrombolytic era - clinical correlates and long-term prognosis Journal of the American College of Cardiology 1990 16:533-540 PMID:2117618
- Popma, J. J., Topol, E. J. Accelerated, combined, and adjunctive thrombolytic strategies for acute myocardial-infarction Current Opinion in Cardiology 1990 5:482-489 DOI:10.1097/00001573-199008000-00017
- George, B. S., Candela, R. J., Topol, E. J., Stack, R. S., Kereiakes, D. J., Abbottsmith, C. W., Masek, R., Pickel, A., Dillon, J., Harrelson, L., Califf, R. M. Brachial approach to emergency cardiac-catheterization during thrombolytic therapy for acute myocardial-infarction Catheterization and Cardiovascular Diagnosis 1990 20:221-226 DOI:10.1002/ccd.1810200402 PMID:2119888
- Williams, D. O., Topol, E. J., Califf, R. M., Roberts, R., Mancini, G. B. J., Joelson, J. M., Ellis, S. G., Kleiman, N. S. Intravenous recombinant tissue-type plasminogen-activator in patients with unstable angina-pectoris - results of a placebo-controlled, randomized trial Circulation 1990 82:376-383 PMID:2115407
- Samson, M., Sutton, J. M., Topol, E. J., Serruys, P. W. Coronary angioplasty in myocardial-infarction - where are we Annales de Cardiologie et d'AngeĢiologie 1990 39:371-377 PMID:2205155
- Topol, E. J. Coronary angioplasty in myocardial infarction Hospital Practice 1990 25:73-76, 79 PMID:2109756
- Kavanaugh, K. M., Topol, E. J. Acute intervention during myocardial-infarction in patients with prior coronary-bypass surgery American Journal of Cardiology 1990 65:924-926 DOI:10.1016/0002-9149(90)91440-h PMID:2321545
- Califf, R. M., Topol, E. J., George, B. S., Kereiakes, D. J., Aronson, L. G., Lee, K. L., Martin, L., Candela, R., Abbottsmith, C., Oneill, W. W., Pryor, D. B., Stack, R. S. One-year outcome after therapy with tissue plasminogen-activator - report from the thrombolysis and angioplasty in myocardial-infarction trial American Heart Journal 1990 119:777-785 DOI:10.1016/s0002-8703(05)80311-4 PMID:2108575
- Sutton, J. M., Topol, E. J. Usefulness of coronary-artery angioplasty strategies in acute myocardial-infarction Canadian Journal of Cardiology 1990 6:111-122 PMID:2187576
- Muller, D. W. M., Topol, E. J., Califf, R. M., Sigmon, K. N., Gorman, L., George, B. S., Kereiakes, D. J., Lee, K. L., Ellis, S. G. Relationship between antecedent angina-pectoris and short-term prognosis after thrombolytic therapy for acute myocardial-infarction American Heart Journal 1990 119:224-231 DOI:10.1016/s0002-8703(05)80008-0 PMID:2405608
- Kander, N. H., Holland, K. J., Pitt, B., Topol, E. J. A randomized pilot trial of brief versus prolonged heparin after successful reperfusion in acute myocardial-infarction American Journal of Cardiology 1990 65:139-142 DOI:10.1016/0002-9149(90)90074-b PMID:2404389
- Popma, J. J., Topol, E. J. Factors influencing restenosis after coronary angioplasty American Journal of Medicine 1990 88:N16-N24
- Vogel, R. A., Shawl, F., Tommaso, C., Oneill, W., Overlie, P., Otoole, J., Vandormael, M., Topol, E., Tabari, K. K., Vogel, J., Smith, S., Freedmann, R., et al. Initial report of the national-registry-of-elective-cardiopulmonary bypass supported coronary angioplasty Journal of the American College of Cardiology 1990 15:23-29 PMID:2404047
- Ellis, S. G., Muller, D. W., Topol, E. J. Possible survival benefit from concomitant beta-antagonist but not calcium-antagonist therapy during reperfusion for acute myocardial-infarction American Journal of Cardiology 1990 66:125-128 DOI:10.1016/0002-9149(90)90574-k PMID:1973588
- Muller, D. W. M., Topol, E. J. Unresolved issues: late reperfusion, lytic failure, and reocclusion Coronary Artery Disease 1990 1:39-49 DOI:10.1097/00019501-199001000-00007
- Sane, D. C., Califf, R. M., Topol, E. J., Stump, D. C., Mark, D. B., Greenberg, C. S. Bleeding during thrombolytic therapy for acute myocardial-infarction - mechanisms and management Annals of Internal Medicine 1989 111:1010-1022 PMID:2688504
- Holmes, D. R., Topol, E. J. Reperfusion momentum - lessons from the randomized trials of immediate coronary angioplasty for myocardial-infarction Journal of the American College of Cardiology 1989 14:1572-1578 DOI:10.1016/0735-1097(89)90401-4 PMID:2809019
- Burek, K. A., Kirscht, J., Topol, E. J. Exercise capacity in patients 3 days after acute, uncomplicated myocardial-infarction Heart & Lung 1989 18:575-582 PMID:2684916
- Califf, R. M., Topol, E. J., Gersh, B. J. From myocardial salvage to patient salvage in acute myocardial-infarction - the role of reperfusion therapy Journal of the American College of Cardiology 1989 14:1382-1388 DOI:10.1016/0735-1097(89)90445-2 PMID:2681322
- Stump, D. C., Califf, R. M., Topol, E. J., Sigmon, K., Thornton, D., Masek, R., Anderson, L., Collen, D. Pharmacodynamics of thrombolysis with recombinant tissue-type plasminogen-activator - correlation with characteristics of and clinical outcomes in patients with acute myocardial-infarction Circulation 1989 80:1222-1230 PMID:2509104
- Ellis, S. G., Topol, E. J., George, B. S., Kereiakes, D. J., Debowey, D., Sigmon, K. N., Pickel, A., Lee, K. L., Califf, R. M. Recurrent ischemia without warning - analysis of risk-factors for in-hospital ischemic events following successful thrombolysis with intravenous tissue plasminogen-activator Circulation 1989 80:1159-1165 PMID:2509102
- Gacioch, G. M., Topol, E. J. Sudden paradoxic clinical deterioration during angioplasty of the occluded right coronary-artery in acute myocardial-infarction Journal of the American College of Cardiology 1989 14:1202-1209 DOI:10.1016/0735-1097(89)90418-x PMID:2808974
- Chapekis, A. T., Burek, K., Topol, E. J. The cost-benefit ratio of acute intervention for myocardial-infarction - results of a prospective, matched pair analysis American Heart Journal 1989 118:878-882 DOI:10.1016/0002-8703(89)90217-2 PMID:2510487
- Topol, E. J., Ellis, S. G., Califf, R. M., George, B. S., Stump, D. C., Bates, E. R., Nabel, E. G., Walton, J. A., Candela, R. J., Lee, K. L., Kline, E. M., Pitt, B. Combined tissue-type plasminogen-activator and prostacyclin therapy for acute myocardial-infarction Journal of the American College of Cardiology 1989 14:877-884 PMID:2477426
- Ellis, S. G., Shaw, R. E., King, S. B., Myler, R. K., Topol, E. J. Restenosis after excellent angiographic angioplasty result for chronic total coronary-artery occlusion - implications for newer percutaneous revascularization devices American Journal of Cardiology 1989 64:667-668 DOI:10.1016/0002-9149(89)90500-6 PMID:2528903
- Muller, D. W. M., Topol, E. J. Acute myocardial infarction: early and late percutaneous trans-luminal coronary angioplasty Current Opinion in Cardiology 1989 4:524-530 DOI:10.1097/00001573-198908000-00012
- Kereiakes, D. J., Topol, E. J., George, B. S., Abbottsmith, C. W., Stack, R. S., Candela, R. J., Oneill, W. W., Anderson, L. C., Califf, R. M. Favorable early and long-term prognosis following coronary-bypass surgery therapy for myocardial-infarction - results of a multicenter trial American Heart Journal 1989 118:199-207 DOI:10.1016/0002-8703(89)90177-4 PMID:2526573
- Kander, N. H., Oneill, W., Topol, E. J., Gallison, L., Mileski, R., Ellis, S. G. Long-term follow-up of patients treated with coronary angioplasty for acute myocardial-infarction American Heart Journal 1989 118:228-233 DOI:10.1016/0002-8703(89)90180-4 PMID:2526574
- Grines, C. L., Topol, E. J., Califf, R. M., Stack, R. S., George, B. S., Kereiakes, D., Boswick, J. M., Kline, E., Oneill, W. W. Prognostic implications and predictors of enhanced regional wall motion of the noninfarct zone after thrombolysis and angioplasty therapy of acute myocardial-infarction Circulation 1989 80:245-253 PMID:2526697
- Muller, D. W. M., Ellis, S. G., Topol, E. J. Atherectomy of the left main coronary-artery with percutaneous cardiopulmonary bypass support American Journal of Cardiology 1989 64:114-116 DOI:10.1016/0002-9149(89)90668-1 PMID:2787097
- Bates, E. R., Topol, E. J. Early hospital discharge in the myocardial reperfusion era Clinical Cardiology 1989 12:65-70 PMID:2691143
- Topol, E. J. Recombinant tissue plasminogen-activator - implications in therapy Seminars in Hematology 1989 26:25-31
- Ellis, S. G., Oneill, W. W., Bates, E. R., Walton, J. A., Nabel, E. G., Werns, S. W., Topol, E. J. Implications for patient triage from survival and left-ventricular functional recovery analyses in 500 patients treated with coronary angioplasty for acute myocardial-infarction Journal of the American College of Cardiology 1989 13:1251-1259 PMID:2522954
- Ellis, S. G., Topol, E. J. Intracoronary stents - will they fulfill their promise as an adjunct to angioplasty Journal of the American College of Cardiology 1989 13:1425-1430 PMID:2522960
- Ellis, S. G., Shaw, R. E., Gershony, G., Thomas, R., Roubin, G. S., Douglas, J. S., Topol, E. J., Startzer, S. H., Myler, R. K., King, S. B. Risk-factors, time course and treatment effect for restenosis after successful percutaneous trans-luminal coronary angioplasty of chronic total occlusion American Journal of Cardiology 1989 63:897-901 DOI:10.1016/0002-9149(89)90135-5 PMID:2522727
- Loscalzo, J., Wharton, T. P., Kirshenbaum, J. M., Levine, H. J., Flaherty, J. T., Topol, E. J., Ramaswamy, K., Kosowsky, B. D., Salem, D. N., Ganz, P., Brinker, J. A., Gurewich, V., et al. Clot-selective coronary thrombolysis with pro-urokinase Circulation 1989 79:776-782 PMID:2494004
- Ellis, S. G., Oneill, W. W., Bates, E. R., Walton, J. A., Nabel, E. G., Topol, E. J. Coronary angioplasty as primary therapy for acute myocardial-infarction 6 to 48 hours after symptom onset - report of an initial experience Journal of the American College of Cardiology 1989 13:1122-1126 PMID:2522467
- Holland, K. J., Oneill, W. W., Bates, E. R., Pitt, B., Topol, E. J. Emergency percutaneous trans-luminal coronary angioplasty during acute myocardial-infarction for patients more than 70 years of age American Journal of Cardiology 1989 63:399-403 DOI:10.1016/0002-9149(89)90307-x PMID:2521765
- Topol, E. J., George, B. S., Kereiakes, D. J., Stump, D. C., Candela, R. J., Abbottsmith, C. W., Aronson, L., Pickel, A., Boswick, J. M., Lee, K. L., Ellis, S. G., Califf, R. M. A randomized controlled trial of intravenous tissue plasminogen-activator and early intravenous heparin in acute myocardial-infarction Circulation 1989 79:281-286 PMID:2492454
- Ellis, S. G., Gallison, L., Grines, C. L., Langburd, A. B., Bates, E. R., Walton, J. A., Oneill, W. W., Topol, E. J. Incidence and predictors of early recurrent ischemia after successful percutaneous trans-luminal coronary angioplasty for acute myocardial-infarction American Journal of Cardiology 1989 63:263-268 DOI:10.1016/0002-9149(89)90327-5 PMID:2521536
- Nicklas, J. M., Topol, E. J., Kander, N., Oneill, W. W., Walton, J. A., Ellis, S. G., Gorman, L., Pitt, B. Randomized, double-blind, placebo-controlled trial of tissue plasminogen-activator in unstable angina Journal of the American College of Cardiology 1989 13:434-441 PMID:2492325
- Bates, E. R., Califf, R. M., Stack, R. S., Aronson, L., George, B. S., Candela, R. J., Kereiakes, D. J., Abbottsmith, C. W., Anderson, L., Pitt, B., Oneill, W. W., Topol, E. J. Thrombolysis and angioplasty in myocardial-infarction (tami-1) trial - influence of infarct location on arterial patency, left-ventricular function and mortality Journal of the American College of Cardiology 1989 13:12-18 PMID:2521226
- Topol, E. J. Coronary angioplasty for acute myocardial-infarction Annals of Internal Medicine 1988 109:970-978 PMID:2973762
- Steinberg, E. P., Topol, E. J., Sakin, J. W., Kahane, S. N., Appel, L. J., Powe, N. R., Anderson, G. F., Erickson, J. E., Guerci, A. D. Cost and procedure implications of thrombolytic therapy for acute myocardial-infarction Journal of the American College of Cardiology 1988 12:A58-A68
- Topol, E. J., Califf, R. M., George, B. S., Kereiakes, D. J., Lee, K. L. Insights derived from the thrombolysis and angioplasty in myocardial-infarction (tami) trials Journal of the American College of Cardiology 1988 12:A24-A31
- Ellis, S. G., Topol, E. J., Gallison, L., Grines, C. L., Langburd, A. B., Bates, E. R., Walton, J. A., Oneill, W. W. Predictors of success for coronary angioplasty performed for acute myocardial-infarction Journal of the American College of Cardiology 1988 12:1407-1415 PMID:2973481
- Carlson, S. E., Aldrich, M. S., Greenberg, H. S., Topol, E. J. Intracerebral hemorrhage complicating intravenous tissue plasminogen-activator treatment Archives of Neurology 1988 45:1070-1073 PMID:3140769
- Grines, C. L., Oneill, W. W., Anselmo, E. G., Juni, J. E., Topol, E. J. Comparison of left-ventricular function and contractile reserve after successful recanalization by thrombolysis versus rescue percutaneous trans-luminal coronary angioplasty for acute myocardial-infarction American Journal of Cardiology 1988 62:352-357 DOI:10.1016/0002-9149(88)90957-5 PMID:2970774
- Topol, E. J., Nicklas, J. M., Kander, N. H., Walton, J. A., Ellis, S. G., Gorman, L., Pitt, B. Coronary revascularization after intravenous tissue plasminogen-activator for unstable angina-pectoris - results of a randomized, double-blind, placebo-controlled trial American Journal of Cardiology 1988 62:368-371 DOI:10.1016/0002-9149(88)90960-5 PMID:2970776
- Califf, R. M., Topol, E. J., George, B. S., Boswick, J. M., Abbottsmith, C., Sigmon, K. N., Candela, R., Masek, R., Kereiakes, D., Oneill, W. W., Stack, R. S., Stump, D. Hemorrhagic complications associated with the use of intravenous tissue plasminogen-activator in treatment of acute myocardial-infarction American Journal of Medicine 1988 85:353-359 DOI:10.1016/0002-9343(88)90586-4 PMID:3137818
- Topol, E. J. An overview of the thrombolysis and angioplasty in acute myocardial infarction (TAMI) trials Archives Des Maladies Du Coeur Et Des Vaisseaux 1988 81:45-49 PMID:2973302
- Califf, R. M., Topol, E. J., George, B. S., Boswick, J. M., Lee, K. L., Stump, D., Dillon, J., Abbottsmith, C., Candela, R. J., Kereiakes, D. J., Oneill, W. W., Stack, R. S. Characteristics and outcome of patients in whom reperfusion with intravenous tissue-type plasminogen-activator fails - results of the thrombolysis and angioplasty in myocardial-infarction (tami) i-trial Circulation 1988 77:1090-1099 PMID:2966016
- Topol, E. J., Califf, R. M., George, B. S., Kereiakes, D. J., Rothbaum, D., Candela, R. J., Abbotsmith, C. W., Pinkerton, C. A., Stump, D. C., Collen, D., Lee, K. L., Pitt, B., et al. Coronary arterial thrombolysis with combined infusion of recombinant tissue-type plasminogen-activator and urokinase in patients with acute myocardial-infarction Circulation 1988 77:1100-1107 PMID:2966017
- Kereiakes, D. J., Topol, E. J., George, B. S., Abbottsmith, C. W., Stack, R. S., Candela, R. J., Oneill, W. W., Martin, L. H., Califf, R. M. Emergency coronary-artery bypass-surgery preserves global and regional left-ventricular function after intravenous tissue plasminogen-activator therapy for acute myocardial-infarction Journal of the American College of Cardiology 1988 11:899-907 PMID:2965716
- Califf, R. M., Oneil, W., Stack, R. S., Aronson, L., Mark, D. B., Mantell, S., George, B. S., Candela, R. J., Kereiakes, D. J., Abbottsmith, C., Topol, E. J. Failure of simple clinical measurements to predict perfusion status after intravenous thrombolysis Annals of Internal Medicine 1988 108:658-662 PMID:3128953
- Topol, E. J., Burek, K., Oneill, W. W., Kewman, D. G., Kander, N. H., Shea, M. J., Schork, M. A., Kirscht, J., Juni, J. E., Pitt, B. A randomized controlled trial of hospital discharge 3 days after myocardial-infarction in the era of reperfusion New England Journal of Medicine 1988 318:1083-1088 DOI:10.1056/nejm198804283181702 PMID:3281014
- Stump, D. C., Topol, E. J., Chen, A. B., Hopkins, A., Collen, D. Monitoring of hemostasis parameters during coronary thrombolysis with recombinant tissue-type plasminogen-activator Thrombosis and Haemostasis 1988 59:133-137 PMID:2455358
- Topol, E. J., George, B. S., Kereiakes, D. J., Candela, R. J., Abbottsmith, C. W., Stump, D. C., Boswick, J. M., Stack, R. S., Califf, R. M. Comparison of 2 dose regimens of intravenous tissue plasminogen-activator for acute myocardial-infarction American Journal of Cardiology 1988 61:723-728 DOI:10.1016/0002-9149(88)91055-7 PMID:2965504
- Humphrey, L. S., Topol, E. J., Rosenfeld, G. I., Borkon, A. M., Baumgartner, W. A., Gardner, T. J., Maruschak, G., Weiss, J. L. Immediate enhancement of left-ventricular relaxation by coronary-artery bypass-grafting - intraoperative assessment Circulation 1988 77:886-896 PMID:3258195
- Grines, C. L., Topol, E. J., Bates, E. R., Juni, J. E., Walton, J. A., Oneill, W. W. Infarct vessel status after intravenous tissue plasminogen-activator and acute coronary angioplasty - prediction of clinical outcome American Heart Journal 1988 115:1-7 DOI:10.1016/0002-8703(88)90510-8 PMID:2962478
- Oneill, W. W., Topol, E. J., Pitt, B. Reperfusion therapy of acute myocardial-infarction Progress in Cardiovascular Diseases 1988 30:235-266 DOI:10.1016/0033-0620(88)90018-7 PMID:3275989
- Guerci, A. D., Gerstenblith, G., Brinker, J. A., Chandra, N. C., Gottlieb, S. O., Bahr, R. D., Weiss, J. L., Shapiro, E. P., Flaherty, J. T., Bush, D. E., Chew, P. H., Gottlieb, S. H., et al. A randomized trial of intravenous tissue plasminogen-activator for acute myocardial-infarction with subsequent randomization to elective coronary angioplasty New England Journal of Medicine 1987 317:1613-1618 DOI:10.1056/nejm198712243172601 PMID:2960897
- Topol, E. J., Bates, E. R., Walton, J. A., Baumann, G., Wolfe, S., Maino, J., Bayer, L., Gorman, L., Kline, E. M., Oneill, W. W., Pitt, B. Community-hospital administration of intravenous tissue plasminogen-activator in acute myocardial-infarction - improved timing, thrombolytic efficacy and ventricular-function Journal of the American College of Cardiology 1987 10:1173-1177 PMID:3119685
- Topol, E. J. Acute intervention for myocardial-infarction Chest 1987 92:929-932 DOI:10.1378/chest.92.5.929 PMID:2959455
- Topol, E. J. Clinical use of streptokinase and urokinase therapy for acute myocardial-infarction Heart & Lung 1987 16:760-774 PMID:3316129
- Topol, E. J., Juni, J. E., Oneill, W. W., Nicklas, J. M., Shea, M. J., Burek, K., Pitt, B. Exercise testing 3 days after onset of acute myocardial-infarction American Journal of Cardiology 1987 60:958-962 DOI:10.1016/0002-9149(87)90332-8 PMID:2960230
- Topol, E. J., Califf, R. M., Kereiakes, D. J., George, B. S. Thrombolysis and angioplasty in myocardial-infarction (tami) trial Journal of the American College of Cardiology 1987 10:B65-B74
- Topol, E. J. Advances in thrombolytic therapy for acute myocardial-infarction Journal of Clinical Pharmacology 1987 27:735-745 PMID:3123526
- Topol, E. J., Califf, R. M., George, B. S., Kereiakes, D. J., Abbottsmith, C. W., Candela, R. J., Lee, K. L., Pitt, B., Stack, R. S., Oneill, W. W. A randomized trial of immediate versus delayed elective angioplasty after intravenous tissue plasminogen-activator in acute myocardial-infarction New England Journal of Medicine 1987 317:581-588 DOI:10.1056/nejm198709033171001 PMID:2956516
- Papadopoulos, S. M., Chandler, W. F., Salamat, M. S., Topol, E. J., Sackellares, J. C. Recombinant human tissue-type plasminogen-activator therapy in acute thromboembolic stroke Journal of Neurosurgery 1987 67:394-398 DOI:10.3171/jns.1987.67.3.0394 PMID:3112328
- Oneill, W. W., Topol, E. J., Fung, A., Bourdillon, P. D. V., Nicklas, J. M., Walton, J., Bates, E. R., Pitt, B. Coronary angioplasty as therapy for acute myocardial infarction: University of Michigan experience Circulation 1987 76:79-87 PMID:2955959
- Bates, E. R., Topol, E. J., Kline, E. M., Langburd, A. B., Fung, A. Y., Walton, J. A., Bourdillon, P. D. V., Vogel, R. A., Pitt, B., Oneill, W. W. Early reperfusion therapy improves left-ventricular function after acute inferior myocardial-infarction associated with right coronary-artery disease American Heart Journal 1987 114:261-267 DOI:10.1016/0002-8703(87)90488-1 PMID:2955688
- Sanz, M. L., Mancini, J., Lefree, M. T., Mickelson, J. K., Starling, M. R., Vogel, R. A., Topol, E. J. Variability of quantitative digital subtraction coronary angiography before and after percutaneous trans-luminal coronary angioplasty American Journal of Cardiology 1987 60:55-60 DOI:10.1016/0002-9149(87)90984-2 PMID:2955693
- Topol, E. J., Morris, D. C., Smalling, R. W., Schumacher, R. R., Taylor, C. R., Nishikawa, A., Liberman, H. A., Collen, D., Tufte, M. E., Grossbard, E. B., Oneill, W. W. A multicenter, randomized, placebo-controlled trial of a new form of intravenous recombinant tissue-type plasminogen-activator (activase) in acute myocardial-infarction Journal of the American College of Cardiology 1987 9:1205-1213 PMID:2953770
- Wind, B. E., Snider, A. R., Buda, A. J., Oneill, W. W., Topol, E. J., Dilworth, L. R. Pulsed doppler assessment of left-ventricular diastolic filling in coronary-artery disease before and immediately after coronary angioplasty American Journal of Cardiology 1987 59:1041-1046 DOI:10.1016/0002-9149(87)90845-9 PMID:2953227
- Kircher, B. J., Topol, E. J., Oneill, W. W., Pitt, B. Prediction of infarct coronary-artery recanalization after intravenous thrombolytic therapy American Journal of Cardiology 1987 59:513-515 DOI:10.1016/0002-9149(87)91158-1 PMID:3825886
- Walsh, D. G., Kaplan, L. R., Burney, R. E., Topol, E. J., Oneill, W. W. Use of tissue plasminogen-activator in the emergency department for acute myocardial-infarction Annals of Emergency Medicine 1987 16:243-247 DOI:10.1016/s0196-0644(87)80166-x PMID:2949679
- Topol, E. J., Oneill, W. W., Langburd, A. B., Walton, J. A., Bourdillon, P. D. V., Bates, E. R., Grines, C. L., Schork, A. M., Kline, E., Pitt, B. A randomized, placebo-controlled trial of intravenous recombinant tissue-type plasminogen-activator and emergency coronary angioplasty in patients with acute myocardial-infarction Circulation 1987 75:420-428 PMID:2948735
- Topol, E. J., Ellis, S. G., Fishman, J., Leimgruber, P., Myler, R. K., Stertzer, S. H., Oneill, W. W., Douglas, J. S., Roubin, G. S., King, S. B. Multicenter study of percutaneous trans-luminal angioplasty for right coronary-artery ostial stenosis Journal of the American College of Cardiology 1987 9:1214-1218 PMID:2953771
- Myler, R. K., Topol, E. J., Shaw, R. E., Stertzer, S. H., Clark, D. A., Fishman, J., Murphy, M. C. Multiple vessel coronary angioplasty - classification, results, and patterns of restenosis in 494 consecutive patients Catheterization and Cardiovascular Diagnosis 1987 13:1-15 DOI:10.1002/ccd.1810130102 PMID:2949849
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