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Rodriguez, Rodrigo
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Rodriguez, Rodrigo

Graduate Student
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Publications

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  • academic article

    • degree-related publication Ma, Z., Wang, X., Wang, X., Rodriguez, R. A., Moore, C. E., Gao, S., Tan, X., Ma, Y., Rheingold, A. L., Baran, P. S., Chen, C. Response to Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence" Science  2015 349:149  DOI:10.1126/science.aaa9626  PMID:26160939  PMCID:PMC4536548
    • degree-related publication Wang, X., Gao, Y., Ma, Z., Rodriguez, R. A., Yu, Z. X., Chen, C. Syntheses of sceptrins and nakamuric acid and insights into the biosyntheses of pyrrole-imidazole dimers Organic Chemistry Frontiers  2015 2:978-984  DOI:10.1039/c5qo00165j  PMID:26328059  PMCID:PMC4551504
    • degree-related publication Rodriguez, R. A., Steed, D. B., Kawamata, Y., Su, S., Smith, P. A., Steed, T. C., Romesberg, F. E., Baran, P. S. Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology Journal of the American Chemical Society  2014 136:15403-15413  DOI:10.1021/ja508632y  PMID:25328977  PMCID:PMC4227811
    • degree-related publication Ma, Z., Wang, X., Wang, X., Rodriguez, R. A., Moore, C. E., Gao, S., Tan, X., Ma, Y., Rheingold, A. L., Baran, P. S., Chen, C. Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence Science  2014 346:219-224  DOI:10.1126/science.1255677  PMID:25301624  PMCID:PMC4205478
    • degree-related publication Rodriguez, R. A., Pan, C. M., Yabe, Y., Kawamata, Y., Eastgate, M. D., Baran, P. S. Palau'chlor: a practical and reactive chlorinating reagent Journal of the American Chemical Society  2014 136:6908-6911  DOI:10.1021/ja5031744  PMID:24758725  PMCID:PMC4333596
    • degree-related publication Fujiwara, Y., Dixon, J. A., O'Hara, F., Funder, E. D., Dixon, D. D., Rodriguez, R. A., Baxter, R. D., Herle, B., Sach, N., Collins, M. R., Ishihara, Y., Baran, P. S. Practical and innate carbon-hydrogen functionalization of heterocycles Nature  2012 492:95-99  DOI:10.1038/nature11680  PMID:23201691  PMCID:PMC3518649
    • degree-related publication Fujiwara, Y., Dixon, J. A., Rodriguez, R. A., Baxter, R. D., Dixon, D. D., Collins, M. R., Blackmond, D. G., Baran, P. S. A new reagent for direct difluoromethylation Journal of the American Chemical Society  2012 134:1494-1497  DOI:10.1021/ja211422g  PMID:22229949  PMCID:PMC3269891
    • degree-related publication Seiple, I. B., Su, S., Young, I. S., Nakamura, A., Yamaguchi, J., Jorgensen, L., Rodriguez, R. A., O'Malley, D. P., Gaich, T., Kock, M., Baran, P. S. Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines Journal of the American Chemical Society  2011 133:14710-14726  DOI:10.1021/ja2047232  PMID:21861522  PMCID:PMC3173569
    • degree-related publication Su, S., Rodriguez, R. A., Baran, P. S. Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B Journal of the American Chemical Society  2011 133:13922-13925  DOI:10.1021/ja206191g  PMID:21846138  PMCID:PMC3164937
    • degree-related publication Seiple, I. B., Su, S., Rodriguez, R. A., Gianatassio, R., Fujiwara, Y., Sobel, A. L., Baran, P. S. Direct C-H arylation of electron-deficient heterocycles with arylboronic acids Journal of the American Chemical Society  2010 132:13194-13196  DOI:10.1021/ja1066459  PMID:20812741  PMCID:PMC2946225
    • Vasko, R. C., Rodriguez, R. A., Cunningham, C. N., Ardi, V. C., Agard, D. A., McAlpine, S. R. Mechanistic studies of Sansalvamide A-amide: an allosteric modulator of Hsp90 ACS Medicinal Chemistry Letters  2010 1:4-8  DOI:10.1021/ml900003f  PMID:20730035  PMCID:PMC2922868
    • Rodriguez, R. A., Pan, P. S., Vasko, R. C., Pan, C. M., Disman, W. S., McAlpine, S. R. Structure-activity of Sansalvamide A derivatives and their apoptotic activity in the pancreatic cancer cell line PL-45 Journal of the Mexican Chemical Society  2008 52:201-211
    • Davis, M. R., Styers, T. J., Rodriguez, R. A., Pan, P. S., Vasko, R. C., McAlpine, S. R. Synthesis and cytotoxicity of a new class of potent decapeptide macrocycles Organic Letters  2008 10:177-180  DOI:10.1021/ol702403r  PMID:18095697
    • Rodriguez, R. A., Pan, P. S., Pan, C. M., Ravula, S., Lapera, S., Singh, E. K., Styers, T. J., Brown, J. D., Cajica, J., Parry, E., Otrubova, K., McAlpine, S. R. Synthesis of second-generation Sansalvamide A derivatives: novel templates as potential antitumor agents Journal of Organic Chemistry  2007 72:1980-2002  DOI:10.1021/jo061830j  PMID:17315929
    • Styers, T. J., Kekec, A., Rodriguez, R., Brown, J. D., Cajica, J., Pan, P. S., Parry, E., Carroll, C. L., Medina, I., Corral, R., Lapera, S., Otrubova, K., et al. Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29 Bioorganic & Medicinal Chemistry  2006 14:5625-5631  DOI:10.1016/j.bmc.2006.04.031  PMID:16697205
    • Styers, T. J., Rodriguez, R., Pan, P. S., McAlpine, S. R. High-yielding macrocyclization conditions used in the synthesis of novel Sansalvamide A derivatives Tetrahedron Letters  2006 47:515-517  DOI:10.1016/j.tetlet.2005.11.056
    • Otrubova, K., Styers, T. J., Pan, P. S., Rodriguez, R., McGuire, K. L., McAlpine, S. R. Synthesis and novel structure-activity relationships of potent sansalvamide A derivatives Chemical Communications  2006 1033-1034  DOI:10.1039/b517434a  PMID:16491200
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Background

education and training

  • Ph.D. in Chemistry, Scripps Research 2008 - 2014
  • B.S. in Chemistry, San Diego State University 2008

advisee of

  • graduate advising relationship

    • Boger, Dale, Ph.D.  candidacy, 2009 - 2014
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Contact

full name

  • Rodrigo A Rodriguez

geographic location

  • Scripps California 

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