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Purse, Byron

Graduate Student

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Positions

• 2013 - Faculty Member, San Diego State University

Websites

• Doctoral Dissertation

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Publications

recent publications

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• academic article

  • Islas, I. J., Stengel, D., Garcia, C. A., Addison, J. B., Samaan, G. N., Holland, G. P., Purse, B. W. 2H NMR reveals liquid state-like dynamics of arene guests inside hexameric pyrogallol[4]arene capsules in the solid state Organic Chemistry Frontiers  2019 6:1361-1366  DOI:10.1039/c9qo00232d  PMID:31178993  PMCID:PMC6550475
  • Bernatchez, J. A., Coste, M., Beck, S., Wells, G. A., Luna, L. A., Clark, A. E., Zhu, Z., Hecht, D., Rich, J. N., Sohl, C. D., Byron, B. W., Siqueira-Neto, J. L. Activity of selected nucleoside analogue protides against zika virus in human neural stem cells Viruses  2019 11  DOI:10.3390/v11040365  PMID:31010044  PMCID:PMC6521205
  • Teppang, K. L., Lee, R. W., Burns, D. D., Turner, M. B., Lokensgard, M. E., Cooksy, A. L., Purse, B. W. Electronic modifications of fluorescent cytidine analogues control photophysics and fluorescent responses to base stacking and pairing Chemistry-a European Journal  2019 25:1249-1259  DOI:10.1002/chem.201803653  PMID:30338571
  • Bernatchez, J. A., Yang, Z., Coste, M., Li, J., Beck, S., Liu, Y., Clark, A. E., Zhu, Z., Luna, L. A., Sohl, C. D., Purse, B. W., Li, R., et al. Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting Zika virus Antimicrobial Agents and Chemotherapy  2018 62:e00725-18  DOI:10.1128/aac.00725-18  PMID:30061280  PMCID:PMC6153842
  • Burns, D. D., Teppang, K. L., Lee, R. W., Lokensgard, M. E., Purse, B. W. Fluorescence turn-on sensing of DNA duplex formation by a tricyclic cytidine analogue Journal of the American Chemical Society  2017 139:1372-1375  DOI:10.1021/jacs.6b10410  PMID:28080035  PMCID:PMC5352299
  • Journey, S. N., Teppang, K. L., Garcia, C. A., Brim, S. A., Onofrei, D., Addison, J. B., Holland, G. P., Purse, B. W. Mechanically induced pyrogallol 4 arene hexamer assembly in the solid state extends the scope of molecular encapsulation Chemical Science  2017 8:7737-7745  DOI:10.1039/c7sc03821f
  • Rodgers, B. J., Elsharif, N. A., Vashisht, N., Mingus, M. M., Mulvahill, M. A., Stengel, G., Kuchta, R. D., Purse, B. W. Functionalized tricyclic cytosine analogues provide nucleoside fluorophores with improved photophysical properties and a range of solvent sensitivities Chemistry-a European Journal  2014 20:2010-2015  DOI:10.1002/chem.201303410  PMID:24311229  PMCID:PMC4020711
  • Chapin, J. C., Purse, B. W. Guest loading, chromatographic purification and controlled release from kinetically trapped, hydrogen-bonded pyrogallol 4 arene capsules Supramolecular Chemistry  2014 26:517-520  DOI:10.1080/10610278.2013.863314
  • Mehdizadeh, E., Chapin, J. C., Gonzales, J. M., Rahafrooz, A., Abdolvand, R., Purse, B. W., Pourkamali, S. Microelectromechanical disk resonators for direct detection of liquid-phase analytes Sensors and Actuators A-Physical  2014 216:136-141  DOI:10.1016/j.sna.2014.05.022
  • Chapin, J. C., Kvasnica, M., Purse, B. W. Molecular encapsulation in pyrogallolarene hexamers under nonequilibrium conditions Journal of the American Chemical Society  2012 134:15000-15009  DOI:10.1021/ja305252t  PMID:22938672
  • Stengel, G., Purse, B. W., Kuchta, R. D. Effect of transition metal ions on the fluorescence and Taq-catalyzed polymerase chain reaction of tricyclic cytidine analogs Analytical Biochemistry  2011 416:53-60  DOI:10.1016/j.ab.2011.04.033  PMID:21600183  PMCID:PMC3151157
  • Kvasnica, M., Chapin, J. C., Purse, B. W. Efficient loading and kinetic trapping of hexameric pyrogallolarene capsules in solution Angewandte Chemie - International Edition  2011 50:2244-2248  DOI:10.1002/anie.201007800  PMID:21351328
  • Stengel, G., Urban, M., Purse, B. W., Kuchta, R. D. Incorporation of the fluorescent ribonucleotide analogue tCTP by T7 RNA polymerase Analytical Chemistry  2010 82:1082-1089  DOI:10.1021/ac902456n  PMID:20067253  PMCID:PMC2819109
  • Urban, M., Joubert, N., Purse, B. W., Hocek, M., Kuchta, R. D. Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate Biochemistry  2010 49:727-735  DOI:10.1021/bi9019516  PMID:20030400  PMCID:PMC2847881
  • Kvasnica, M., Purse, B. W. Specific tetramethylammonium recognition drives general anion positioning in tandem sites of a deep cavitand New Journal of Chemistry  2010 34:1097-1099  DOI:10.1039/c0nj00224k
  • Stengel, G., Purse, B. W., Wilhelmsson, L. M., Urban, M., Kuchta, R. D. Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment Biochemistry  2009 48:7547-7555  DOI:10.1021/bi9006995  PMID:19580325  PMCID:PMC2748917
  • Stengel, G., Urban, M., Purse, B. W., Kuchta, R. D. High density labeling of polymerase chain reaction products with the fluorescent base analogue tCo Analytical Chemistry  2009 81:9079-9085  DOI:10.1021/ac9017555  PMID:19810708  PMCID:PMC2784673
  • Johansson, M., Purse, B. W., Terasaki, O., Backvall, J. E. Aerobic oxidations catalyzed by zeolite-encapsulated cobalt salophen Advanced Synthesis & Catalysis  2008 350:1807-1815  DOI:10.1002/adsc.200800294
  • Purse, B. W., Tran, L. H., Piera, J., Akermark, B., Backvall, J. E. Synthesis of new hybrid hydroquinone/cobalt Schiff base catalysts: Efficient electron-transfer mediators in aerobic oxidation Chemistry-A European Journal  2008 14:7500-7503  DOI:10.1002/chem.200800657  PMID:18604855
  • Purse, B. W., Butterfield, S. M., Ballester, P., Shivanyuk, A., Rebek, J. Interaction energies and dynamics of acid-base pairs isolated in cavitands Journal of Organic Chemistry  2008 73:6480-6488  DOI:10.1021/jo8008534  PMID:18672933  PMCID:PMC2717715
  • Purse, B. W., Rebek, J. Self-fulfilling cavitands: Packing alkyl chains into small spaces Proceedings of the National Academy of Sciences of the United States of America  2006 103:2530-2534  DOI:10.1073/pnas.0511149103  PMID:16477037  PMCID:PMC1413836
  • Purse, B. W., Gissot, A., Rebek, J. A deep cavitand provides a structured environment for the menschutkin reaction Journal of the American Chemical Society  2005 127:11222-11223  DOI:10.1021/ja052877+  PMID:16089433
  • Purse, B. W., Rebek, J. Encapsulation of oligoethylene glycols and perfluoro-n-alkanes in a cylindrical host molecule Chemical Communications  2005 722-724  DOI:10.1039/b408878f  PMID:15685316
  • Purse, B. W., Rebek, J. Functional cavitands: Chemical reactivity in structured environments Proceedings of the National Academy of Sciences of the United States of America  2005 102:10777-10782  DOI:10.1073/pnas.0501731102  PMID:16043720  PMCID:PMC1182416
  • Purse, B. W., Ballester, P., Rebek, J. Reactivity and molecular recognition: Amine methylation by an introverted ester Journal of the American Chemical Society  2003 125:14682-14683  DOI:10.1021/ja036595q  PMID:14640624
  • Purse, B. W., Shivanyuk, A., Rebek, J. Resorcin[6]arene as a building block for tubular crystalline state architectures Chemical Communications  2002 2612-2613  DOI:10.1039/b208189j  PMID:12510262
  • Nitz, M., Purse, B. W., Bundle, D. R. Synthesis of a beta1,2-mannopyranosyl tetrasaccharide found in the phosphomannan antigen of Candida albicans Organic Letters  2000 2:2939-2942  DOI:10.1021/ol0061743  PMID:10986077

Background

education and training

• Ph.D. in Chemistry, Scripps Research 2000 - 2005
• B.Sc. in Chemistry and Biochemistry, University of Regina , with Honours 1996 - 2000

advisee of

• graduate advising relationship

  • Rebek Jr., Julius, Ph.D.  candidacy, 2001 - 2005

Contact

full name

• Byron Willis Purse

geographic location

• Scripps California