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Ichu, Taka-Aki
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Ichu, Taka-Aki

Graduate Student
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Publications

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  • academic article

    • degree-related publication Bi, J., Ichu, T. A., Zanca, C., Yang, H., Zhang, W., Gu, Y., Chowdhry, S., Reed, A., Ikegami, S., Turner, K. M., Zhang, W., Villa, G. R., et al. Oncogene amplification in growth factor signaling pathways renders cancers dependent on membrane lipid remodeling Cell Metabolism  2019 30:525-538  DOI:10.1016/j.cmet.2019.06.014  PMID:31303424  PMCID:PMC6742496
    • degree-related publication Ogasawara, D., Ichu, T. A., Jing, H., Hulce, J. J., Reed, A., Ulanovskaya, O. A., Cravatt, B. F. Discovery and optimization of selective and in vivo active inhibitors of the lysophosphatidylserine lipase α/β-hydrolase domain-containing 12 (ABHD12) Journal of Medicinal Chemistry  2019 62:1643-1656  DOI:10.1021/acs.jmedchem.8b01958  PMID:30720278
    • degree-related publication Ogasawara, D., Ichu, T. A., Vartabedian, V. F., Benthuysen, J., Jing, H., Reed, A., Ulanovskaya, O. A., Hulce, J. J., Roberts, A., Brown, S., Rosen, H., Teijaro, J. R., et al. Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo Nature Chemical Biology  2018 14:1099-1108  DOI:10.1038/s41589-018-0155-8  PMID:30420694  PMCID:PMC6263940
    • degree-related publication Bar-Peled, L.*, Kemper, E. K.*, Suciu, R. M., Vinogradova, E. V., Backus, K. M., Horning, B. D., Paul, T. A., Ichu, T. A., Svensson, R. U., Olucha, J., Chang, M. W., Kok, B. P., et al. Chemical proteomics identifies druggable vulnerabilities in a genetically defined cancer Cell  2017 171:696-709  DOI:10.1016/j.cell.2017.08.051  PMID:28965760 (* = equal contribution)
    • Maher, S. K., Wojnarowicz, P., Ichu, T. A., Veldhoen, N., Lu, L., Lesperance, M., Propper, C. R., Helbing, C. C. Rethinking the biological relationships of the thyroid hormones, L-thyroxine and 3,5,3 '-triiodothyronine Comparative Biochemistry and Physiology D-Genomics & Proteomics  2016 18:44-53  DOI:10.1016/j.cbd.2016.04.002  PMID:27085304
    • degree-related publication Niphakis, M. J., Lum, K. M., Cognetta III, A. B., Correia, B. E., Ichu, T. A., Olucha, J., Brown, S. J., Kundu, S., Piscitelli, F., Rosen, H., Cravatt, B. F. A global map of lipid-binding proteins and their ligandability in cells Cell  2015 161:1668-1680  DOI:10.1016/j.cell.2015.05.045  PMID:26091042  PMCID:PMC4615699
    • Ichu, T. A., Han, J., Borchers, C. H., Lesperance, M., Helbing, C. C. Metabolomic insights into system-wide coordination of vertebrate metamorphosis BMC Developmental Biology  2014 14  DOI:10.1186/1471-213x-14-5  PMID:24495308  PMCID:PMC3928663
    • Cheng, S. W. G., Kuzyk, M. A., Moradian, A., Ichu, T. A., Chang, V. C. D., Tien, J. F., Vollett, S. E., Griffith, M., Marra, M. A., Morin, G. B. Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II Molecular and Cellular Biology  2012 32:4691-4704  DOI:10.1128/mcb.06267-11  PMID:22988298  PMCID:PMC3486194
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Background

education and training

  • Ph.D. in Biology, Scripps Research 2014 -
  • B.S. in Statistics, University of Victoria 2012

advisee of

  • graduate advising relationship

    • Cravatt, Benjamin, Ph.D.  candidacy, 2015 -
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Contact

full name

  • Taka-Aki Ichu

geographic location

  • Scripps California 

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