Glinkerman, Christopher

Graduate Student

Positions

2018 - Postdoctoral Research Associate, Whitehead Institute for Biomedical Research , Massachusetts Institute of Technology

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Doctoral Dissertation

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academic article
- Angelbello, A. J., Defeo, M. E., Glinkerman, C. M., Boger, D. L., Disney, M. D. Precise Targeted Cleavage of a r(CUG) Repeat Expansion in Cells by Using a Small-Molecule-Deglycobleomycin Conjugate ACS Chemical Biology 2020 15:849-855 DOI:10.1021/acschembio.0c00036 PMCID:32186845
- Zhu, Z., Glinkerman, C. M., Boger, D. L. Selective N1/N4 1,4-Cycloaddition of 1,2,4,5-Tetrazines Enabled by Solvent Hydrogen Bonding Journal of the American Chemical Society 2020 142:20778-20787 DOI:10.1021/jacs.0c09775 PMID:33252223 PMCID:PMC7725851
- Ozog, S., Timberlake, N. D., Hermann, K., Garijo, O., Haworth, K. G., Shi, G., Glinkerman, C. M., Schefter, L. E., D'Souza, S., Simpson, E., Sghia-Hughes, G., Carillo, R. R., et al. Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes Blood 2019 134:1298-1311 DOI:10.1182/blood.2019000040 PMID:31416800
- Glinkerman, C. M., Boger, D. L. Synthesis, characterization, and rapid cycloadditions of 5-nitro-1,2,3-triazine Organic Letters 2018 20:2628-2631 DOI:10.1021/acs.orglett.8b00825 PMID:29659291 PMCID:PMC5935562
- Quinones, R. E., Glinkerman, C. M., Zhu, K., Boger, D. L. Direct synthesis of β-aminoenals through reaction of 1,2,3-triazine with secondary amines Organic Letters 2017 19:3568-3571 DOI:10.1021/acs.orglett.7b01543 PMID:28657329
- Glinkerman, C. M., Boger, D. L. Catalysis of heterocyclic azadiene cycloaddition reactions by solvent hydrogen bonding: concise total synthesis of methoxatin Journal of the American Chemical Society 2016 138:12408-12413 DOI:10.1021/jacs.6b05438 PMID:27571404 PMCID:PMC5042865
- Feldman, K. S., Gonzalez, I. Y., Glinkerman, C. M. Indolidenes and indolidenium intermediates in the synthesis of cyclopent[b]indoles: mechanistic studies on intramolecular cyclizations Journal of Organic Chemistry 2015 80:11849-11862 DOI:10.1021/acs.joc.5b01777 PMID:26348264
- Lee, K., Poudel, Y. B., Glinkerman, C. M., Boger, D. L. Total synthesis of dihydrolysergic acid and dihydrolysergol: development of a divergent synthetic strategy applicable to rapid assembly of D-ring analogs Tetrahedron 2015 71:5897-5905 DOI:10.1016/j.tet.2015.05.093 PMID:26273113 PMCID:PMC4528678
- Glinkerman, C. M., Boger, D. L. Cycloadditions of 1,2,3-triazines bearing C5-electron donating substituents: robust pyrimidine synthesis Organic Letters 2015 17:4002-4005 DOI:10.1021/acs.orglett.5b01870 PMID:26172042 PMCID:PMC4546508
- Feldman, K. S., Gonzalez, I. Y., Glinkerman, C. M. Intramolecular [3 + 2] cyclocondensations of alkenes with indolidenes and indolidenium cations Journal of the American Chemical Society 2014 136:15138-15141 DOI:10.1021/ja508421e PMID:25322063
- Anderson, E. D., Duerfeldt, A. S., Zhu, K., Glinkerman, C. M., Boger, D. L. Cycloadditions of noncomplementary substituted 1,2,3-triazines Organic Letters 2014 16:5084-5087 DOI:10.1021/ol502436n PMID:25222918 PMCID:PMC4184932