recent publications
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academic article
- Zhong, Y. L., Gauthier, D. R., Shi, Y. J., McLaughlin, M., Chung, J. Y. L., Dagneau, P., Marcune, B., Krska, S. W., Ball, R. G., Reamer, R. A., Yasuda, N. Synthesis of Antifungal Glucan Synthase Inhibitors from Enfumafungin Journal of Organic Chemistry 2012 77:3297-3310 DOI:10.1021/jo300046v
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Nicolaou, K. C.*, Ortiz, A.*, Zhang, H. J., Dagneau, P., Lanver, A., Jennings, M. P., Arseniyadis, S., Faraoni, R., Lizos, D. E. Total synthesis and structural revision of vannusals A and B: synthesis of the originally assigned structure of vannusal B Journal of the American Chemical Society 2010 132:7138-7152 DOI:10.1021/ja100740t PMID:20443561 PMCID:PMC2881636 (* = equal contribution)
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Nicolaou, K. C., Zhang, H., Ortiz, A., Dagneau, P. Total synthesis of the originally assigned structure of vannusal B Angewandte Chemie-International Edition 2008 47:8605-8610 DOI:10.1002/anie.200804228 PMID:18850598 PMCID:PMC2790063
- O'Shea, P. D., Chen, C. Y., Chen, W., Dagneau, P., Frey, L. F., Grabowski, E. J. J., Marcantonio, K. M., Reamer, R. A., Tan, L., Tillyer, R. D., Roy, A., Wang, X., et al. Practical asymmetric synthesis of a potent PDE4 inhibitor via stereoselective enolate alkylation of a chiral aryl-heteroaryl secondary tosylate Journal of Organic Chemistry 2005 70:3021-3030 DOI:10.1021/jo048156v PMID:15822960
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Nicolaou, K. C., Tang, W. J., Dagneau, P., Faraoni, R. A catalytic asymmetric three-component 1,4-addition/aldol reaction: Enantioselective synthesis of the spirocyclic system of vannusal a Angewandte Chemie-International Edition 2005 44:3874-3879 DOI:10.1002/anie.200500789 PMID:15900527
- Chen, C. Y., Dagneau, P., Grabowski, E. J. J., Oballa, R., O'Shea, P., Prasit, P., Robichaud, J., Tillyer, R., Wang, X. Practical asymmetric synthesis of a potent cathepsin K inhibitor. Efficient palladium removal following Suzuki coupling Journal of Organic Chemistry 2003 68:2633-2638 DOI:10.1021/jo0205614 PMID:12662032
- Tan, L., Chen, C. Y., Chen, W., Frey, L., King, A. O., Tillyer, R. D., Xu, F., Zhao, D., Grabowski, E. J. J., Reider, P. J., O'Shea, P., Dagneau, P., et al. Practical enantioselective synthesis of a COX-2 specific inhibitor Tetrahedron 2002 58:7403-7410 DOI:10.1016/s0040-4020(02)00826-8
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Nicolaou, K. C., Jennings, M. P., Dagneau, P. An expedient entry into the fused polycyclic skeleton of vannusal a Chemical Communications 2002 2480-2481 DOI:10.1039/b208234a
- Stahl, S., Tillyer, R., King, A., Dagneau, P., Wang, X., O'Shea, P., Greasham, R., Chartrain, M. Asymmetric bioreduction of an allylic ketosulfone to its corresponding (R)-alcohol Biocatalysis and Biotransformation 2000 18:471-477 DOI:10.3109/10242420009015264
- Dagneau, P., Canonne, P. An efficient synthesis of the natural (+)-fulvanin 1 Tetrahedron-Asymmetry 1996 7:2817-2820 DOI:10.1016/0957-4166(96)00370-9