recent publications
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academic article
- Chong, Y. E., Guo, M., Yang, X. L., Kuhle, B., Naganuma, M., Sekine, S., Yokoyama, S., Schimmel, P. Distinct ways of G:U recognition by conserved tRNA binding motifs Proceedings of the National Academy of Sciences of the United States of America 2018 115:7527-7532 DOI:10.1073/pnas.1807109115 PMID:29967150 PMCID:PMC6055181
- Xu, Z., Lo, W. S., Beck, D. B., Schuch, L. A., Olahova, M., Kopajtich, R., Chong, Y. E., Alston, C. L., Seidl, E., Zhai, L., Lau, C. F., Timchak, D., et al. Bi-allelic mutations in phe-tRNA synthetase associated with a multi-system pulmonary disease Support non-translational function American Journal of Human Genetics 2018 103:100-114 DOI:10.1016/j.ajhg.2018.06.006 PMID:29979980 PMCID:PMC6035289
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Naganuma, M., Sekine, S., Chong, Y. E., Guo, M., Yang, X. L., Gamper, H., Hou, Y. M., Schimmel, P., Yokoyama, S.
The selective tRNA aminoacylation mechanism based on a single G.U pair
Nature
2014
510:507-511
DOI:10.1038/nature13440
PMID:24919148
PMCID:PMC4323281
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He, W., Zhang, H. M., Chong, Y. E., Guo, M., Marshall, A. G., Yang, X. L.
Dispersed disease-causing neomorphic mutations on a single protein promote the same localized conformational opening
Proceedings of the National Academy of Sciences of the United States of America
2011
108:12307-12312
DOI:10.1073/pnas.1104293108
PMID:21737751
PMCID:PMC3145702
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Han, G. W., Yang, X. L., McMullan, D., Chong, Y. E., Krishna, S. S., Rife, C. L., Weekes, D., Brittain, S. M., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., et al.
Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster
Acta Crystallographica Section F-Structural Biology and Crystallization Communications
2010
66:1326-1334
DOI:10.1107/s1744309110037619
PMID:20944229
PMCID:PMC2954223
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Guo, M., Chong, Y. E., Shapiro, R., Beebe, K., Yang, X. L., Schimmel, P.
Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma
Nature
2009
462:808-812
DOI:10.1038/nature08612
PMID:20010690
PMCID:PMC2799227
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Guo, R. T., Chong, Y. E., Guo, M., Yang, X. L.
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis
Journal of Biological Chemistry
2009
284:28968-28976
DOI:10.1074/jbc.M109.030692
PMID:19710017
PMCID:PMC2781443
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Guo, M., Chong, Y. E., Beebe, K., Shapiro, R., Yang, X. L., Schimmel, P.
The C-Ala domain brings together editing and aminoacylation functions on one tRNA
Science
2009
325:744-747
DOI:10.1126/science.1174343
PMID:19661429
PMCID:PMC4559334
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Chong, Y. E., Yang, X. L., Schimmel, P.
Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation
Journal of Biological Chemistry
2008
283:30073-30078
DOI:10.1074/jbc.M805943200
PMID:18723508
PMCID:PMC2573062