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Calarese, Daniel A
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Calarese, Daniel A

Graduate Student
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Positions

  • 2019 - Associate Director, Protein Engineering, Sutro Biopharma
  • 2016 - 2019 Senior Scientist, Protein Engineering, Sutro Biopharma
  • 2014 - 2016 Scientist, Protein Engineering, Sutro Biopharma
  • 2012 - 2014 Associate Faculty Member, Department of Biochemistry, Albert Einstein College of Medicine
  • 2006 - 2011 Postdoctoral Fellow, The Rockefeller University

Websites

  • Doctoral Dissertation
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Publications

recent publications
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  • academic article

    • Boskovic, Z. V., Kemp, M. M., Freedy, A. M., Viswanathan, V. S., Pop, M. S., Fuller, J. H., Martinez, N. M., Lazu, S. O. F., Hong, J. A., Lewis, T. A., Calarese, D., Love, J. D., et al. Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile ACS Chemical Biology  2016 11:1844-1851  DOI:10.1021/acschembio.6b00012  PMID:27064299
    • Nguyen, K. Q. N., Tsou, W. I., Calarese, D. A., Kimani, S. G., Singh, S., Hsieh, S., Liu, Y., Lu, B., Wu, Y., Garforth, S. J., Almo, S. C., Kotenko, S. V., et al. Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity Journal of Biological Chemistry  2014 289:25737-25749  DOI:10.1074/jbc.M114.570838  PMID:25074939  PMCID:PMC4162176
    • Tsou, W. I., Nguyen, K. Q. N., Calarese, D. A., Garforth, S. J., Antes, A. L., Smirnov, S. V., Almo, S. C., Birge, R. B., Kotenko, S. V. Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation Journal of Biological Chemistry  2014 289:25750-25763  DOI:10.1074/jbcM114.569020  PMID:25074926  PMCID:PMC4162177
    • degree-related publication Menendez, A., Calarese, D. A., Stanfield, R. L., Chow, K. C., Scanlan, C. N., Kunert, R., Katinger, H., Burton, D. R., Wilson, I. A., Scott, J. K. A peptide inhibitor of hiv-1 neutralizing antibody 2g12 is not a structural mimic of the natural carbohydrate epitope on gp120 FASEB Journal  2008 22:1380-1392  DOI:10.1096/fj.07-8983com  PMID:18198210  PMCID:PMC2430149
    • degree-related publication Calarese, D. A., Lee, H. K., Huang, C. Y., Best, M. D., Astronomo, R. D., Stanfield, R. L., Katinger, H., Burton, D. R., Wong, C. H., Wilson, I. A. Dissection of the carbohydrate specificity of the broadly neutralizing-anti-hiv-1 antibody 2g12 Proceedings of the National Academy of Sciences of the United States of America  2005 102:13372-13377  DOI:10.1073/pnas.0505763102  PMID:16174734  PMCID:PMC1224641
    • degree-related publication Scanlan, C., Lee, H. K., Blixt, O., Wong, C. H., Wilson, I., Burton, D., Dwek, R., Rudd, P. Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design Advances in Experimental Medicine and Biology  2005 564:7-8  DOI:10.1007/0-387-25515-X_4  PMID:16400800
    • degree-related publication Blixt, O., Head, S., Mondala, T., Scanlan, C., Huflejt, M. E., Alvarez, R., Bryan, M. C., Fazio, F., Calarese, D., Stevens, J., Razi, N., Stevens, D. J., et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins Proceedings of the National Academy of Sciences of the United States of America  2004 101:17033-17038  DOI:10.1073/pnas.0407902101  PMID:15563589  PMCID:PMC534418
    • degree-related publication Bryan, M. C., Fazio, F., Lee, H. K., Huang, C. Y., Chang, A., Best, M. D., Calarese, D. A., Blixt, C., Paulson, J. C., Burton, D., Wilson, I. A., Wong, C. H. Covalent display of oligosaccharide arrays in microtiter plates Journal of the American Chemical Society  2004 126:8640-8641  DOI:10.1021/ja048433f  PMID:15250702
    • degree-related publication Lee, H. K., Scanlan, C. N., Huang, C. Y., Chang, A. Y., Calarese, D. A., Dwek, R. A., Rudd, P. M., Burton, D. R., Wilson, I. A., Wong, C. H. Reactivity-based one-pot synthesis of oligomannoses: Defining antigens recognized by 2g12, a broadly neutralizing anti-hiv-1 antibody Angewandte Chemie-International Edition  2004 43:1000-1003  DOI:10.1002/anie.200353105  PMID:14966891
    • degree-related publication Calarese, D. A., Scanlan, C. N., Zwick, M. B., Deechongkit, S., Mimura, Y., Kunert, R., Zhu, P., Wormald, M. R., Stanfield, R. L., Roux, K. H., Kelly, J. W., Rudd, P. M. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition Science  2003 300:2065-2071  DOI:10.1126/science.1083182  PMID:12829775
    • degree-related publication Scanlan, C. N., Pantophlet, R., Wormald, M. R., Saphire, E. O., Calarese, D., Stanfield, R., Wilson, I. A., Katinger, H., Dwek, R. A., Burton, D. R., Rudd, P. M. The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12 Advances in Experimental Medicine and Biology  2003 535:205-218  DOI:10.1007/978-1-4615-0065-0_13  PMID:14714897
  • chapter

    • degree-related publication Calarese, D., Scanlan, C., Lee, H. K., Rudd, P., Dwek, R. Toward a carbohydrate-based HIV-1 vaccine ACS Symposium Series. 161-185. 2006  DOI:10.1021/bk-2006-0932.ch007
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Background

education and training

  • Ph.D. in Macromolecular and Cellular Structure and Chemistry, Scripps Research 2001 - 2006
  • B.A. in Molecular and Cell Biology, Cornell University 1997 - 2001

advisee of

  • graduate advising relationship

    • Wilson, Ian, Ph.D.  candidacy, 2002 - 2006
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Contact

full name

  • Daniel A Calarese

geographic location

  • Scripps California 

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