recent publications
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academic article
- Kingston, C., Palkowitz, M. D., Takahira, Y., Vantourout, J. C., Peters, B. K., Kawamata, Y., Baran, P. S. A survival guide for the "Electro-curious" Accounts of Chemical Research 2020 53:72-83 DOI:10.1021/acs.accounts.9b00539 PMID:31823612 PMCID:PMC6996934
- Flood, D. T., Kingston, C., Vantourout, J. C., Dawson, P. E., Baran, P. S. DNA encoded libraries: a visitor's guide Israel Journal of Chemistry 2020 DOI:10.1002/ijch.201900133
- Minteer, S. D., Baran, P. Electrifying Synthesis: Recent Advances in the Methods, Materials, and Techniques for Organic Electrosynthesis Accounts of Chemical Research 2020 53:545-546 DOI:10.1021/acs.accounts.0c00049 PMID:32178522
- Kawamata, Y., Baran, P. S. Electrosynthesis: Sustainability Is Not Enough Joule 2020 4:701-704 DOI:10.1016/j.joule.2020.02.002
- Xu, D., Rivas-Bascon, N., Padial, N. M., Knouse, K. W., Zheng, B., Vantourout, J. C., Schmidt, M. A., Eastgate, M. D., Baran, P. S. Enantiodivergent Formation of C-P Bonds: Synthesis of P-Chiral Phosphines and Methylphosphonate Oligonucleotides Journal of the American Chemical Society 2020 142:5785-5792 DOI:10.1021/jacs.9b13898 PMID:32109356
- Flood, D. T., Zhang, X. J., Fu, X., Zhao, Z. X., Asai, S., Sanchez, B. B., Sturgell, E. J., Vantourout, J. C., Richardson, P., Flanagan, M. E., Piotrowski, D. W., K?lmel, D. K., et al. RASS-Enabled S/P-C and S-N Bond Formation for DEL Synthesis Angewandte Chemie-International Edition 2020 59:7377-7383 DOI:10.1002/anie.201915493 PMID:32050046
- McClymont, K. S., Wang, F. Y., Minakar, A., Baran, P. S. Total Synthesis of (-)-Maximiscin Journal of the American Chemical Society 2020 142:8608-8613 DOI:10.1021/jacs.0c03202 PMID:32338003
- Reisberg, S. H., Gao, Y., Walker, A. S., Helfrich, E. J. N., Clardy, J., Baran, P. S. Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A Science 2020 367:458-463 DOI:10.1126/science.aay9981 PMID:31896661 PMCID:PMC6996792
- Nakamura, H., Yasui, K., Kanda, Y., Baran, P. S. 11-step total synthesis of teleocidins B-1-6-4 Journal of the American Chemical Society 2019 141:1494-1497 DOI:10.1021/jacs.8b13697 PMID:30636411 PMCID:PMC6353666
- Ni, S., Munoz Padial, N., Kingston, C., Vantourout, J. C., Schmitt, D. C., Edwards, J. T., Kruszyk, M., Merchant, R. R., Mykhailiuk, P. K., Sanchez, B., Yang, S., Perry, M., et al. A radical approach to anionic chemistry: synthesis of ketones, alcohols, and amines Journal of the American Chemical Society 2019 141:6726-6739 DOI:10.1021/jacs.9b02238 PMID:30943023
- Smith, J. M., Dixon, J. A., deGruyter, J. N., Baran, P. S. Alkyl sulfinates: radical precursors enabling drug discovery Journal of Medicinal Chemistry 2019 62:2256-2264 DOI:10.1021/acs.jmedchem.8b01303 PMID:30272973
- Kawamata, Y., Baran, P. S. Cluster preface: electrochemical synthesis and catalysis Synlett 2019 30:1147-1148 DOI:10.1055/s-0039-1689970
- He, C., Stratton, T. P., Baran, P. S. Concise total synthesis of herqulines B and C Journal of the American Chemical Society 2019 141:29-32 DOI:10.1021/jacs.8b13029 PMID:30575396
- Mediouni, S., Chinthalapudi, K., Ekka, M. K., Usui, I., Jablonski, J. A., Clementz, M. A., Mousseau, G., Nowak, J., Macherla, V. R., Beverage, J. N., Esquenazi, E., Baran, P., et al. Didehydro-cortistatin A inhibits HIV-1 by specifically binding to the unstructured basic region of Tat MBio 2019 10:e02662-18 DOI:10.1128/mBio.02662-18 PMID:30723126 PMCID:PMC6368365
- Kingston, C., Wallace, M. A., Allentoff, A. J., deGruyter, J. N., Chen, J. S., Gong, S. X., Bonacorsi, S., Baran, P. S. Direct carbon isotope exchange through decarboxylative carboxylation Journal of the American Chemical Society 2019 141:774-779 DOI:10.1021/jacs.8b12035 PMID:30605319
- Takahira, Y., Chen, M., Kawamata, Y., Mykhailiuk, P., Nakamura, H., Peters, B. K., Reisberg, S. H., Li, C., Chen, L., Hoshikawa, T., Shibuguchi, T., Baran, P. S. Electrochemical C(sp(3))-H fluorination Synlett 2019 30:1178-1182 DOI:10.1055/s-0037-1611737
- Kawamata, Y., Vantourout, J. C., Hickey, D. P., Bai, P., Chen, L., Hou, Q., Qiao, W., Barman, K., Edwards, M. A., Garrido-Castro, A. F., DeGruyter, J. N., Nakamura, H., et al. Electrochemically driven, Ni-catalyzed aryl amination: scope, mechanism, and applications Journal of the American Chemical Society 2019 141:6392-6402 DOI:10.1021/jacs.9b01886 PMID:30905151
- Flood, D. T., Asai, S., Zhang, X., Wang, J., Yoon, L., Adams, Z. C., Dillingham, B. C., Sanchez, B. B., Vantourout, J. C., Flanagan, M. E., Piotrowsld, D. W., Richardson, P., et al. Expanding reactivity in DNA-encoded library synthesis via reversible binding of DNA to an inert quaternary ammonium support Journal of the American Chemical Society 2019 141:9998-10006 DOI:10.1021/jacs.9b03774 PMID:31136164
- Xiang, J., Shang, M., Kawamata, Y., Lundberg, H., Reisberg, S. H., Chen, M., Mykhailiuk, P., Beutner, G., Collins, M. R., Davies, A., Del Bel, M., Gallego, G. M., et al. Hindered dialkyl ether synthesis with electrogenerated carbocations Nature 2019 573:398-402 DOI:10.1038/s41586-019-1539-y PMID:31501569
- Barton, L. M., Edwards, J. T., Johnson, E. C., Bukowski, E. J., Sausa, R. C., Byrd, E. F. C., Orlicki, J. A., Sabatini, J. J., Baran, P. S. Impact of stereo- and regiochemistry on energetic materials Journal of the American Chemical Society 2019 141:12531-12535 DOI:10.1021/jacs.9b06961 PMID:31361955
- Shang, M., Feu, K. S., Vantourout, J. C., Barton, L. M., Osswald, H. L., Kato, N., Gagaring, K., McNamara, C. W., Chen, G., Hu, L., Ni, S., Fernandez-Canelas, P., et al. Modular, stereocontrolled Cβ-H/Cα-C activation of alkyl carboxylic acids Proceedings of the National Academy of Sciences of the United States of America 2019 116:8721-8727 DOI:10.1073/pnas.1903048116 PMID:30996125 PMCID:PMC6500144
- Chen, T. G., Zhang, H., Mykhailiuk, P. K., Merchant, R. R., Smith, C. A., Qin, T., Baran, P. S. Quaternary centers by nickel-catalyzed cross-coupling of tertiary carboxylic acids and (hetero)aryl zinc reagents Angewandte Chemie-International Edition 2019 58:2454-2458 DOI:10.1002/anie.201814524 PMID:30623547 PMCID:PMC6391118
- Peters, B. K., Rodriguez, K. X., Reisberg, S. H., Beil, S. B., Hickey, D. P., Kawamata, Y., Collins, M., Starr, J., Chen, L., Udyavara, S., Klunder, K., Gorey, T. J., et al. Scalable and safe synthetic organic electroreduction inspired by Li-ion battery chemistry Science 2019 363:838-845 DOI:10.1126/science.aav5606 PMID:30792297
- Ni, S. Y., Garrido-Castro, A. F., Merchant, R. R., de Gruyter, J. N., Schmitt, D. C., Mousseau, J. J., Gallego, G. M., Yang, S., Collins, M. R., Qiao, J. X., Yeung, K. S., Langley, D. R., et al. A general amino acid synthesis enabled by innate radical cross-coupling Angewandte Chemie-International Edition 2018 57:14560-14565 DOI:10.1002/anie.201809310 PMID:30212610
- Chen, T. G., Barton, L. M., Lin, Y., Tsien, J., Kossler, D., Bastida, I., Asai, S., Bi, C., Chen, J. S., Shan, M., Fang, H., Fang, F. G., et al. Building C(sp3)-rich complexity by combining cycloaddition and C-C cross-coupling reactions Nature 2018 560:350-354 DOI:10.1038/s41586-018-0391-9 PMID:30061620
- Wang, J., Shang, M., Lundberg, H., Feu, K. S., Hecker, S. J., Qin, T., Blackmond, D. G., Baran, P. S. Cu-catalyzed decarboxylative borylation ACS Catalysis 2018 8:9537-9542 DOI:10.1021/acscatal.8b02928
- Merchant, R. R., Oberg, K. M., Lin, Y., Novak, A. J. E., Felding, J., Baran, P. S. Divergent synthesis of pyrone diterpenes via radical cross coupling Journal of the American Chemical Society 2018 140:7462-7465 DOI:10.1021/jacs.8b04891 PMID:29921130 PMCID:PMC6016063
- Chu, H., Dunstl, G., Felding, J., Baran, P. S. Divergent synthesis of thapsigargin analogs Bioorganic & Medicinal Chemistry Letters 2018 28:2705-2707 DOI:10.1016/j.bmcl.2018.03.065 PMID:29636219 PMCID:PMC6119632
- Wang, J., Lundberg, H., Asai, S., Martin-Acosta, P., Chen, J. S., Brown, S., Farrell, W., Dushin, R. G., O'Donnell, C. J., Ratnayake, A. S., Richardson, P., Liu, Z., et al. Kinetically guided radical-based synthesis of C(sp(3))-C(sp(3)) linkages on DNA Proceedings of the National Academy of Sciences of the United States of America 2018 115:E6404-E6410 DOI:10.1073/pnas.1806900115 PMID:29946037 PMCID:PMC6048552
- Merchant, R. R.*, Edwards, J. T.*, Qin, T., Kruszyk, M. M., Bi, C., Che, G., Bao, D. H., Qiao, W., Sun, L., Collins, M. R., Fadeyi, O. O., Gallego, G. M., et al. Modular radical cross-coupling with sulfones enables access to sp(3)-rich (fluoro)alkylated scaffolds Science 2018 360:75-80 DOI:10.1126/science.aar7335 PMID:29456201 (* = equal contribution)
- Baran, P. S. Natural product total synthesis: as exciting as ever and here to stay Journal of the American Chemical Society 2018 140:4751-4755 DOI:10.1021/jacs.8b02266 PMID:29635919
- Smith, J. M., Harwood, S. J., Baran, P. S. Radical retrosynthesis Accounts of Chemical Research 2018 51:1807-1817 DOI:10.1021/acs.accounts.8b00209 PMID:30070821
- Peters, D. S., Romesberg, F. E., Baran, P. S. Scalable access to arylomycins via C-H functionalization logic Journal of the American Chemical Society 2018 140:2072-2075 DOI:10.1021/jacs.8b00087 PMID:29381350 PMCID:PMC5817625
- Yan, M., Kawamata, Y., Baran, P. S. Synthetic organic electrochemistry: calling all engineers Angewandte Chemie-International Edition 2018 57:4149-4155 DOI:10.1002/anie.201707584 PMID:28834012 PMCID:PMC5823775
- Knouse, K. W.*, deGruyter, J. N.*, Schmidt, M. A., Zheng, B., Vantourout, J. C., Kingston, C., Mercer, S. E., McDonald, I. M., Olson, R. E., Zhu, Y., Hang, C., Zhu, J., et al. Unlocking P(V): Reagents for chiral phosphorothioate synthesis Science 2018 361:1234-1238 DOI:10.1126/science.aau3369 PMID:30072577 (* = equal contribution)
- Sandfort, F., O'Neill, M. J., Cornella, J., Wimmer, L., Baran, P. S. Alkyl-(hetero)aryl bond formation via decarboxylative cross-coupling: A systematic analysis Angewandte Chemie-International Edition 2017 56:3319-3323 DOI:10.1002/anie.201612314 PMID:28185368
- Yan, M., Baran, P. S. BMS-663068: Another quiet victory for chemistry Organic Process Research & Development 2017 21:1091-1094 DOI:10.1021/acs.oprd.7b00208
- Degruyter, J. N., Malins, L. R., Wimmer, L., Clay, K. J., Lopez-Ogalla, J., Qin, T., Cornella, J., Liu, Z., Che, G., Bao, D., Stevens, J. M., Ojao, J. X., et al. CITU: a peptide and decarboxylative coupling reagent Organic Letters 2017 19:6196-6199 DOI:10.1021/acs.orglett.7b03121 PMID:29115835 PMCID:PMC5792187
- Parker, C. G., Kuttruff, C. A., Galmozzi, A., Jørgensen, L., Yeh, C.-H., Hermanson, D. J., Wang, Y., Artola, M., McKerrall, S. J., Josyln, C. M., Nørremark, B., Dünstl, G., et al. Chemical proteomics identifies SLC25A20 as a functional target of the ingenol class of actinic keratosis drugs ACS Central Science 2017 3:1276-1285 DOI:10.1021/acscentsci.7b00420 PMID:29296668 PMCID:PMC5746860
- Edwards, J. T., Merchant, R. R., McClymont, K. S., Knouse, K. W., Qin, T., Malins, L. R., Vokits, B., Shaw, S. A., Bao, D. H., Wei, F. L., Zhou, T., Eastgate, M. D., et al. Decarboxylative alkenylation Nature 2017 545:213-218 DOI:10.1038/nature22307 PMID:28424520
- Smith, J. M., Qin, T., Merchant, R. R., Edwards, J. T., Malins, L. R., Liu, Z., Che, G., Shen, Z., Shaw, S. A., Eastgate, M. D., Baran, P. S. Decarboxylative alkynylation Angewandte Chemie-International Edition 2017 56:11906-11910 DOI:10.1002/anie.201705107 PMID:28636185 PMCID:PMC5792189
- Li, C., Wang, J., Barton, L. M., Yu, S., Tian, M., Peters, D. S., Kumar, M., Yu, A. W., Johnson, K. A., Chatterjee, A. K., Yan, M., Baran, P. S. Decarboxylative borylation Science 2017 356 DOI:10.1126/science.aam7355 PMID:28408721
- Trammell, R., See, Y. Y., Herrmann, A. T., Xie, N., Diaz, D. E., Siegler, M. A., Baran, P. S., Garcia-Bosch, I. Decoding the Mechanism of Intramolecular Cu-Directed Hydroxylation of sp3 C-H Bonds Journal of Organic Chemistry 2017 82:7887-7904 DOI:10.1021/acs.joc.7b01069 PMID:28654755
- Mathur, A., Wang, B., Smith, D., Li, J., Pawluczyk, J., Sun, J. H., Wong, M. K., Krishnananthan, S., Wu, D. R., Sun, D., Li, P., Yip, S., et al. Development of the large-scale synthesis of tetrahydropyran glycine, a precursor to the HCV NS5A inhibitor BMS-986097 Journal of Organic Chemistry 2017 82:10376-10387 DOI:10.1021/acs.joc.7b01852 PMID:28877441
- Li, C., Kawamata, Y., Nakamura, H., Vantourout, J. C., Liu, Z., Hou, Q., Bao, D., Starr, J. T., Chen, J., Yan, M., Baran, P. S. Electrochemically enabled, nickel-catalyzed amination Angewandte Chemie-International Edition 2017 56:13088-13093 DOI:10.1002/anie.201707906 PMID:28834098
- Lo, J. C., Kim, D., Pan, C. M., Edwards, J. T., Yabe, Y., Gui, J. H., Qin, T., Gutierrez, S., Giacoboni, J., Smith, M. W., Holland, P. L., Baran, P. S. Fe-catalyzed C-C bond construction from olefins via radicals Journal of the American Chemical Society 2017 139:2484-2503 DOI:10.1021/jacs.6b13155 PMID:28094980 PMCID:PMC5314431
- Qin, T., Malins, L. R., Edwards, J. T., Merchant, R. R., Novak, A. J. E., Zhong, J. Z., Mills, R. B., Yan, M., Yuan, C., Eastgate, M. D., Baran, P. S. Nickel-catalyzed barton decarboxylation and giese reactions: a practical take on classic transforms Angewandte Chemie-International Edition 2017 56:260-265 DOI:10.1002/anie.201609662 PMID:27981703 PMCID:PMC5295468
- Malins, L. R., deGruyter, J. N., Robbins, K. J., Scola, P. M., Eastgate, M. D., Ghadiri, M. R., Baran, P. S. Peptide macrocyclization inspired by non-ribosomal imine natural products Journal of the American Chemical Society 2017 139:5233-5241 DOI:10.1021/jacs.7b01624 PMID:28326777 PMCID:PMC5391502
- deGruyter, J. N., Malins, L. R., Baran, P. S. Residue-Specific Peptide Modification: A Chemist's Guide Biochemistry 2017 56:3863-3873 DOI:10.1021/acs.biochem.7b00536 PMID:28653834
- Chu, H., Smith, J. M., Felding, J., Baran, P. S. Scalable synthesis of (-)-thapsigargin ACS Central Science 2017 3:47-51 DOI:10.1021/acscentsci.6b00313 PMID:28149952 PMCID:PMC5269647
- Kawamata, Y., Yan, M., Liu, Z., Bao, D. H., Chen, J., Starr, J. T., Baran, P. S. Scalable, electrochemical oxidation of unactivated C-H bonds Journal of the American Chemical Society 2017 139:7448-7451 DOI:10.1021/jacs.7b03539 PMID:28510449 PMCID:PMC5465511
- Lopchuk, J. M., Fjelbye, K., Kawamata, Y., Malins, L. R., Pan, C. M., Gianatassio, R., Wang, J., Prieto, L., Bradow, J., Brandt, T. A., Collins, M. R., Elleraas, J., et al. Strain-release heteroatom functionalization: Development, scope, and stereospecificity Journal of the American Chemical Society 2017 139:3209-3226 DOI:10.1021/jacs.6b13229 PMID:28140573 PMCID:PMC5334783
- Yan, M., Kawamata, Y., Baran, P. S. Synthetic organic electrochemical methods since 2000: on the verge of a renaissance Chemical Reviews 2017 117:13230-13319 DOI:10.1021/acs.chemrev.7b00397 PMID:28991454
- Cernijenko, A., Risgaard, R., Baran, P. S. 11-step total synthesis of (-)-maoecrystal V Journal of the American Chemical Society 2016 138:9425-9428 DOI:10.1021/jacs.6b06623 PMID:27457680 PMCID:PMC4974602
- Tian, M., Yan, M., Baran, P. S. 11-step total synthesis of araiosamines Journal of the American Chemical Society 2016 138:14234-14237 DOI:10.1021/jacs.6b09701 PMID:27748593 PMCID:PMC5095662
- Martinez, L. P., Umemiya, S., Wengryniuk, S. E., Baran, P. S. 11-step total synthesis of pallambins C and D Journal of the American Chemical Society 2016 138:7536-7539 DOI:10.1021/jacs.6b04816 PMID:27284962 PMCID:PMC4919752
- Qin, T., Cornella, J., Li, C., Malins, L. R., Edwards, J. T., Kawamura, S., Maxwell, B. D., Eastgate, M. D., Baran, P. S. A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents Science 2016 352:801-805 DOI:10.1126/science.aaf6123 PMID:27103669 PMCID:PMC4867118
- Quesnelle, C. A., Gill, P., Kim, S. H., Chen, L., Zhao, Y., Fink, B. E., Saulnier, M., Frennesson, D., DeMartino, M. P., Baran, P. S., Gavai, A. V. A practical approach for enantio- and diastereocontrol in the synthesis of 2,3-disubstituted succinic acid esters: synthesis of the pan-Notch inhibitor BMS-906024 Synlett 2016 27:2254-2258 DOI:10.1055/s-0035-1561636
- Villaume, M. T., Sella, E., Saul, G., Borzilleri, R. M., Fargnoli, J., Johnston, K. A., Zhang, H., Fereshteh, M. P., Dhar, T. G. M., Baran, P. S. Antroquinonol A: scalable synthesis and preclinical biology of a phase 2 drug candidate ACS Central Science 2016 2:27-31 DOI:10.1021/acscentsci.5b00345 PMID:27163023 PMCID:PMC4827469
- Yan, M., Baran, P. S. Drug discovery: Fighting evolution with chemical synthesis Nature 2016 533:326-327 PMID:27193674
- Wang, J., Qin, T., Chen, T. G., Wimmer, L., Edwards, J. T., Cornella, J., Vokits, B., Shaw, S. A., Baran, P. S. Nickel-catalyzed cross-coupling of redox-active esters with boronic acids Angewandte Chemie-International Edition 2016 55:9675-9678 DOI:10.1002/anie.201605463 PMID:27380912 PMCID:PMC5232357
- Kawamura, S., Chu, H., Felding, J., Baran, P. S. Nineteen-step total synthesis of (+)-phorbol Nature 2016 532:90-93 DOI:10.1038/nature17153 PMID:27007853 PMCID:PMC4833603
- Cornella, J., Edwards, J. T., Qin, T., Kawamura, S., Wang, J., Pan, C. M., Gianatassio, R., Schmidt, M., Eastgate, M. D., Baran, P. S. Practical Ni-catalyzed aryl-alkyl cross-coupling of secondary redox-active esters Journal of the American Chemical Society 2016 138:2174-2177 DOI:10.1021/jacs.6b00250 PMID:26835704 PMCID:PMC4768290
- Yan, M., Lo, J. C., Edwards, J. T., Baran, P. S. Radicals: reactive intermediates with translational potential Journal of the American Chemical Society 2016 138:12692-12714 DOI:10.1021/jacs.6b08856 PMID:27631602 PMCID:PMC5054485
- Toriyama, F., Cornella, J., Wimmer, L., Chen, T. G., Dixon, D. D., Creech, G., Baran, P. S. Redox-active esters in Fe-catalyzed C-C coupling Journal of the American Chemical Society 2016 138:11132-11135 DOI:10.1021/jacs.6b07172 PMID:27548696 PMCID:PMC5016806
- Horn, E. J., Rosen, B. R., Chen, Y., Tang, J., Chen, K., Eastgate, M. D., Baran, P. S. Scalable and sustainable electrochemical allylic C-H oxidation Nature 2016 533:77-81 DOI:10.1038/nature17431 PMID:27096371 PMCID:PMC4860034
- Yuan, C., Jin, Y., Wilde, N. C., Baran, P. S. Short, enantioselective total synthesis of highly oxidized taxanes Angewandte Chemie-International Edition 2016 55:8280-8284 DOI:10.1002/anie.201602235 PMID:27240325 PMCID:PMC4972021
- Gianatassio, R., Lopchuk, J. M., Wang, J., Pan, C. M., Malins, L. R., Prieto, L., Brandt, T. A., Collins, M. R., Gallego, G. M., Sach, N. W., Spangler, J. E., Zhu, H., et al. Strain-release amination Science 2016 351:241 DOI:10.1126/science.aad6252 PMID:26816372 PMCID:PMC4730898
- Horn, E. J., Rosen, B. R., Baran, P. S. Synthetic organic electrochemistry: an enabling and innately sustainable method ACS Central Science 2016 2:302-308 DOI:10.1021/acscentsci.6b00091 PMID:27280164 PMCID:PMC4882743
- Gnaim, S., Scomparin, A., Li, X., Baran, P. S., Rader, C., Satchi-Fainaro, R., Shabat, D. Tagging the untaggable: a difluoroalkyl-sulfinate ketone-based reagent for direct C-H functionalization of bioactive heteroarenes Bioconjugate Chemistry 2016 27:1965-1971 DOI:10.1021/acs.bioconjchem.6b00382 PMID:27494153
- Jin, Y., Yeh, C. H., Kuttruff, C. A., Jorgensen, L., Dünstl, G., Felding, J., Natarajan, S. R., Baran, P. S. C-H oxidation of ingenanes enables potent and selective protein kinase C isoform activation Angewandte Chemie-International Edition 2015 54:14044-14048 DOI:10.1002/anie.201507977 PMID:26418078 PMCID:PMC4832842
- Michaudel, Q., Ishihara, Y., Baran, P. S. Academia-industry symbiosis in organic chemistry Accounts of Chemical Research 2015 48:712-721 DOI:10.1021/ar500424a PMID:25702529 PMCID:PMC4365666
- Smith, M. W., Baran, P. S. As simple as 2+2 Science 2015 349:925-926 DOI:10.1126/science.aac9883
- Renata, H., Zhou, Q., Dunstl, G., Felding, J., Merchant, R. R., Yeh, C. H., Baran, P. S. Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues Journal of the American Chemical Society 2015 137:1330-1340 DOI:10.1021/ja512022r PMID:25594682 PMCID:PMC4353025
- Gavai, A. V., Quesnelle, C., Norris, D., Han, W. C., Gill, P., Shan, W., Balog, A., Chen, K., Tebben, A., Rampulla, R., Wu, D. R., Zhang, Y., et al. Discovery of clinical candidate BMS-906024: A potent pan-notch inhibitor for the treatment of leukemia and solid tumors ACS Medicinal Chemistry Letters 2015 6:523-527 DOI:10.1021/acsmedchemlett.5b00001 PMID:26005526 PMCID:PMC4434460
- Dao, H. T., Li, C., Michaudel, Q., Maxwell, B. D., Baran, P. S. Hydromethylation of unactivated olefins Journal of the American Chemical Society 2015 137:8046-8049 DOI:10.1021/jacs.5b05144 PMID:26088401 PMCID:PMC4490774
- Farmer, M. E., Baran, P. S. Organic chemistry: A cure for catalyst poisoning Nature 2015 524:164-165 PMID:26268186
- Gui, J., Pan, C. M., Jin, Y., Qin, T., Lo, J. C., Lee, B. J., Spergel, S. H., Mertzman, M. E., Pitts, W. J., La Cruz, T. E., Schmidt, M. A., Darvatkar, N., et al. Practical olefin hydroamination with nitroarenes Science 2015 348:886-891 DOI:10.1126/science.aab0245 PMID:25999503
- Ma, Z., Wang, X., Wang, X., Rodriguez, R. A., Moore, C. E., Gao, S., Tan, X., Ma, Y., Rheingold, A. L., Baran, P. S., Chen, C. Response to Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence" Science 2015 349:149 DOI:10.1126/science.aaa9626 PMID:26160939 PMCID:PMC4536548
- See, Y. Y., Herrmann, A. T., Aihara, Y., Baran, P. S. Scalable C-H oxidation with copper: synthesis of polyoxypregnanes Journal of the American Chemical Society 2015 137:13776-13779 DOI:10.1021/jacs.5b09463 PMID:26466196
- Maimone, T. J., Ishihara, Y., Baran, P. S. Scalable total syntheses of (-)-hapalindole U and (+)-ambiguine H Tetrahedron 2015 71:3652-3665 DOI:10.1016/j.tet.2014.11.010 PMID:25983347 PMCID:PMC4430130
- Shaw, S. A., Balasubramanian, B., Bonacorsi, S., Cortes, J. C., Cao, K., Chen, B. C., Dai, J., Decicco, C., Goswami, A., Guo, Z., Hanson, R., Humphreys, W. G., et al. Synthesis of biologically active piperidine metabolites of clopidogrel: determination of structure and analyte development Journal of Organic Chemistry 2015 80:7019-7032 DOI:10.1021/acs.joc.5b00632 PMID:26151079
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- Lo, J. C., Yabe, Y., Baran, P. S. A practical and catalytic reductive olefin coupling Journal of the American Chemical Society 2014 136:1304-1307 DOI:10.1021/ja4117632 PMID:24428607 PMCID:PMC3971728
- O'Hara, F., Burns, A. C., Collins, M. R., Dalvie, D., Ornelas, M. A., Vaz, A. D. N., Fujiwara, Y., Baran, P. S. A simple litmus test for aldehyde oxidase metabolism of heteroarenes Journal of Medicinal Chemistry 2014 57:1616-1620 DOI:10.1021/jm4017976 PMID:24472070 PMCID:PMC3983350
- Cherney, E. C., Lopchuk, J. M., Green, J. C., Baran, P. S. A unified approach to ent-atisane diterpenes and related alkaloids: synthesis of (-)-methyl atisenoate, (-)-isoatisine, and the hetidine skeleton Journal of the American Chemical Society 2014 136:12592-12595 DOI:10.1021/ja507321J PMID:25159015 PMCID:PMC4160278
- Gutekunst, W. R., Baran, P. S. Applications of C-H functionalization logic to cyclobutane synthesis Journal of Organic Chemistry 2014 79:2430-2452 DOI:10.1021/jo4027148 PMID:24548142 PMCID:PMC3985916
- Ma, Z., Wang, X., Wang, X., Rodriguez, R. A., Moore, C. E., Gao, S., Tan, X., Ma, Y., Rheingold, A. L., Baran, P. S., Chen, C. Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence Science 2014 346:219-224 DOI:10.1126/science.1255677 PMID:25301624 PMCID:PMC4205478
- Rodriguez, R. A., Steed, D. B., Kawamata, Y., Su, S., Smith, P. A., Steed, T. C., Romesberg, F. E., Baran, P. S. Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology Journal of the American Chemical Society 2014 136:15403-15413 DOI:10.1021/ja508632y PMID:25328977 PMCID:PMC4227811
- Gui, J., Zhou, Q., Pan, C. M., Yabe, Y., Burns, A. C., Collins, M. R., Ornelas, M. A., Ishihara, Y., Baran, P. S. C-H methylation of heteroarenes inspired by radical SAM methyl transferase Journal of the American Chemical Society 2014 136:4853-4856 DOI:10.1021/ja5007838 PMID:24611732 PMCID:PMC3988686
- Baran, P. S. Carlos F. Barbas III (1964-2014) Angewandte Chemie-International Edition 2014 53:9704-9705 DOI:10.1002/anie.201407049 PMID:25082355
- McKerrall, S. J., Jorgensen, L., Kuttruff, C. A., Ungeheuer, F., Baran, P. S. Development of a concise synthesis of (+)-ingenol Journal of the American Chemical Society 2014 136:5799-5810 DOI:10.1021/ja501881p PMID:24712341
- Lo, J. C., Gui, J., Yabe, Y., Pan, C. M., Baran, P. S. Functionalized olefin cross-coupling to construct carbon-carbon bonds Nature 2014 516:343-348 DOI:10.1038/nature14006 PMID:25519131 PMCID:PMC4271735
- Michaudel, Q., Journot, G., Regueiro-Ren, A., Goswami, A., Guo, Z., Tully, T. P., Zou, L., Ramabhadran, R. O., Houk, K. N., Baran, P. S. Improving physical properties via C-H oxidation: chemical and enzymatic approaches Angewandte Chemie-International Edition 2014 53:12091-12096 DOI:10.1002/anie.201407016 PMID:25244630 PMCID:PMC4226272
- Hong, X., Holte, D., Gotz, D. C. G., Baran, P. S., Houk, K. N. Mechanism, reactivity, and selectivity of nickel-catalyzed [4 + 4 + 2] cycloadditions of dienes and alkynes Journal of Organic Chemistry 2014 79:12177-12184 DOI:10.1021/jo502219d PMID:25325891 PMCID:PMC4275152
- Kuttruff, C. A., Eastgate, M. D., Baran, P. S. Natural product synthesis in the age of scalability Natural Product Reports 2014 31:419-432 DOI:10.1039/c3np70090a PMID:24337165
- Teufel, R., Kaysser, L., Villaume, M. T., Diethelm, S., Carbullido, M. K., Baran, P. S., Moore, B. S. One-pot enzymatic synthesis of merochlorin A and B Angewandte Chemie-International Edition 2014 53:11019-11022 DOI:10.1002/anie.201405694 PMID:25115835 PMCID:PMC4229033
- Rodriguez, R. A., Pan, C. M., Yabe, Y., Kawamata, Y., Eastgate, M. D., Baran, P. S. Palau'chlor: a practical and reactive chlorinating reagent Journal of the American Chemical Society 2014 136:6908-6911 DOI:10.1021/ja5031744 PMID:24758725 PMCID:PMC4333596
- Dao, H. T., Baran, P. S. Quinone diazides for olefin functionalization Angewandte Chemie-International Edition 2014 53:14382-14386 DOI:10.1002/anie.201408022 PMID:25367639
- O'Brien, A. G., Maruyama, A., Inokuma, Y., Fujita, M., Baran, P. S., Blackmond, D. G. Radical C-H functionalization of heteroarenes under electrochemical control Angewandte Chemie-International Edition 2014 53:11868-11871 DOI:10.1002/anie.201407948 PMID:25209429 PMCID:PMC4214156
- Villaume, M. T., Baran, P. S. Reactivity tamed one bond at a time Nature 2014 513:324-325 DOI:10.1038/513324a PMID:25230652
- Gianatassio, R., Kawamura, S., Eprile, C. L., Foo, K., Ge, J., Burns, A. C., Collins, M. R., Baran, P. S. Simple sulfinate synthesis enables C-H trifluoromethylcyclopropanation Angewandte Chemie-International Edition 2014 53:9851-9855 DOI:10.1002/anie.201406622 PMID:25088979 PMCID:PMC4186797
- Rosen, B. R., Werner, E. W., O'Brien, A. G., Baran, P. S. Total synthesis of dixiamycin B by electrochemical oxidation Journal of the American Chemical Society 2014 136:5571-5574 DOI:10.1021/ja5013323 PMID:24697810 PMCID:PMC4004216
- Wilde, N. C., Isomura, M., Mendoza, A., Baran, P. S. Two-phase synthesis of (-)-taxuyunnanine D Journal of the American Chemical Society 2014 136:4909-4912 DOI:10.1021/ja501782r PMID:24625050 PMCID:PMC3985808
- Teufel, R., Miyanaga, A., Michaudel, Q., Stull, F., Louie, G., Noel, J. P., Baran, P. S., Palfey, B., Moore, B. S. Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement Nature 2013 503:552-556 DOI:10.1038/nature12643 PMID:24162851 PMCID:PMC3844076
- Jorgensen, L., McKerrall, S. J., Kuttruff, C. A., Ungeheuer, F., Felding, J., Baran, P. S. 14-step synthesis of (+)-ingenol from (+)-3-carene Science 2013 341:878-882 DOI:10.1126/science.1241606 PMID:23907534
- Zhou, Q., Gui, J., Pan, C. M., Albone, E., Cheng, X., Suh, E. M., Grasso, L., Ishihara, Y., Baran, P. S. Bioconjugation by native chemical tagging of C-H bonds Journal of the American Chemical Society 2013 135:12994-12997 DOI:10.1021/ja407739y PMID:23957305 PMCID:PMC3812917
- Rosen, B. R., Simke, L. R., Thuy-Boun, P. S., Dixon, D. D., Yu, J. Q., Baran, P. S. C-H functionalization logic enables synthesis of (+)-hongoquercin A and related compounds Angewandte Chemie-International Edition 2013 52:7317-7320 DOI:10.1002/anie.201303838 PMID:23740529
- Usui, I., Lin, D. W., Masuda, T., Baran, P. S. Convergent synthesis and structural confirmation of phellodonin and sarcodonin epsilon Organic Letters 2013 15:2080-2083 DOI:10.1021/ol400709f PMID:23577748 PMCID:PMC3653569
- Zhou, Q. H., Ruffoni, A., Gianatassio, R., Fujiwara, Y., Sella, E., Shabat, D., Baran, P. S. Direct synthesis of fluorinated heteroarylether bioisosteres Angewandte Chemie-International Edition 2013 52:3949-3952 DOI:10.1002/anie.201300763 PMID:23460402 PMCID:PMC3643141
- Zou, L., Paton, R. S., Eschenmoser, A., Newhouse, T. R., Baran, P. S., Houk, K. N. Enhanced reactivity in dioxirane C-H oxidations via strain release: a computational and experimental study Journal of Organic Chemistry 2013 78:4037-4048 DOI:10.1021/jo400350v PMID:23461537 PMCID:PMC3631471
- O'Hara, F., Baxter, R. D., O'Brien, A. G., Collins, M. R., Dixon, J. A., Fujiwara, Y., Ishihara, Y., Baran, P. S. Preparation and purification of zinc sulfinate reagents for drug discovery Nature Protocols 2013 8:1042-1047 DOI:10.1038/nprot.2013.059 PMID:23640168 PMCID:PMC4114315
- O'Hara, F., Blackmond, D. G., Baran, P. S. Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability Journal of the American Chemical Society 2013 135:12122-12134 DOI:10.1021/ja406223k PMID:23859263 PMCID:PMC3776592
- Wengryniuk, S. E., Weickgenannt, A., Reiher, C., Strotman, N. A., Chen, K., Eastgate, M. D., Baran, P. S. Regioselective bromination of fused heterocyclic N-oxides Organic Letters 2013 15:792-795 DOI:10.1021/ol3034675 PMID:23350852
- Renata, H., Zhou, Q. H., Baran, P. S. Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide Science 2013 339:59-63 DOI:10.1126/science.1230631 PMID:23288535 PMCID:PMC4365795
- Cherney, E. C., Green, J. C., Baran, P. S. Synthesis of ent-kaurane and beyerane diterpenoids by controlled fragmentations of overbred intermediates Angewandte Chemie-International Edition 2013 52:9019-9022 DOI:10.1002/anie.201304609 PMID:23861294 PMCID:PMC3814173
- Ishihara, Y., Mendoza, A., Baran, P. S. Total synthesis of taxane terpenes: cyclase phase Tetrahedron 2013 69:5685-5701 DOI:10.1016/j.tet.2013.04.028 PMID:23794756 PMCID:PMC3685884
- Karton-Lifshin, N., Albertazzi, L., Bendikov, M., Baran, P. S., Shabat, D. "Donor-two-acceptor" dye design: a distinct gateway to NIR fluorescence Journal of the American Chemical Society 2012 134:20412-20420 DOI:10.1021/ja308124q PMID:23194283
- Fujiwara, Y., Dixon, J. A., O'Hara, F., Funder, E. D., Dixon, D. D., Rodriguez, R. A., Baxter, R. D., Herle, B., Sach, N., Collins, M. R., Ishihara, Y., Baran, P. S. Practical and innate carbon-hydrogen functionalization of heterocycles Nature 2012 492:95-99 DOI:10.1038/nature11680 PMID:23201691 PMCID:PMC3518649
- Mendoza, A., Baran, P. S. Synthesis: A constructive debate Nature 2012 492 DOI:10.1038/492188a PMID:23235869
- Fujiwara, Y., Dixon, J. A., Rodriguez, R. A., Baxter, R. D., Dixon, D. D., Collins, M. R., Blackmond, D. G., Baran, P. S. A new reagent for direct difluoromethylation Journal of the American Chemical Society 2012 134:1494-1497 DOI:10.1021/ja211422g PMID:22229949 PMCID:PMC3269891
- Mousseau, G., Clementz, M. A., Bakeman, W. N., Nagarsheth, N., Cameron, M., Shi, J., Baran, P., Fromentin, R., Chomont, N., Valente, S. T. An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription Cell Host & Microbe 2012 12:97-108 DOI:10.1016/j.chom.2012.05.016 PMID:22817991 PMCID:PMC3403716
- Holte, D., Gotz, D. C. G., Baran, P. S. An approach to mimicking the sesquiterpene cyclase phase by nickel-promoted diene/alkyne cooligomerization Journal of Organic Chemistry 2012 77:825-842 DOI:10.1021/jo202314a PMID:22229741 PMCID:PMC3264824
- Kock, M., Schmidt, G., Seiple, I. B., Baran, P. S. Configurational analysis of tetracyclic dimeric pyrrole-imidazole alkaloids using a floating chirality approach Journal of Natural Products 2012 75:127-130 DOI:10.1021/np200514g PMID:22332969 PMCID:PMC3315375
- Porter, D. C., Farmaki, E., Altilia, S., Schools, G. P., West, D. K., Chen, M. Q., Chang, B. D., Puzyrev, A. T., Lim, C. U., Rokow-Kittell, R., Friedhoff, L. T., Papavassiliou, A. G., et al. Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities Proceedings of the National Academy of Sciences of the United States of America 2012 109:13799-13804 DOI:10.1073/pnas.1206906109 PMID:22869755 PMCID:PMC3427077
- Voica, A. F., Mendoza, A., Gutekunst, W. R., Fraga, J. O., Baran, P. S. Guided desaturation of unactivated aliphatics Nature Chemistry 2012 4:629-635 DOI:10.1038/nchem.1385 PMID:22824894 PMCID:PMC3405363
- Bruckl, T., Baxter, R. D., Ishihara, Y., Baran, P. S. Innate and guided C-H functionalization logic Accounts of Chemical Research 2012 45:826-839 DOI:10.1021/ar200194b PMID:22017496 PMCID:PMC3288638
- Michaudel, Q., Thevenet, D., Baran, P. S. Intermolecular Ritter-type C-H amination of unactivated sp3 carbons Journal of the American Chemical Society 2012 134:2547-2550 DOI:10.1021/ja212020b PMID:22276612 PMCID:PMC3277284
- Lansdell, T. A., Hewlett, N. M., Skoumbourdis, A. P., Fodor, M. D., Seiple, I. B., Su, S., Baran, P. S., Feldman, K. S., Tepe, J. J. Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20s proteasome Journal of Natural Products 2012 75:980-985 DOI:10.1021/np300231f PMID:22591513 PMCID:PMC3367325
- Mendoza, A., Ishihara, Y., Baran, P. S. Scalable enantioselective total synthesis of taxanes Nature Chemistry 2012 4:21-25 DOI:10.1038/nchem.1196 PMID:22169867 PMCID:PMC3243931
- Dixon, D. D., Lockner, J. W., Zhou, Q. H., Baran, P. S. Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide" Journal of the American Chemical Society 2012 134:8432-8435 DOI:10.1021/ja303937y PMID:22583115
- Foo, K., Usui, I., Gotz, D. C. G., Werner, E. W., Holte, D., Baran, P. S. Scalable, enantioselective synthesis of germacrenes and related sesquiterpenes inspired by terpene cyclase phase logic Angewandte Chemie-International Edition 2012 51:11491-11495 DOI:10.1002/anie.201206904 PMID:23065776 PMCID:PMC3628789
- Gutekunst, W. R., Gianatassio, R., Baran, P. S. Sequential C(sp3)-H arylation and olefination: total synthesis of the proposed structure of pipercyclobutanamide A Angewandte Chemie-International Edition 2012 51:7507-7510 DOI:10.1002/anie.201203897 PMID:22715157 PMCID:PMC3495593
- Gulder, T., Baran, P. S. Strained cyclophane natural products: Macrocyclization at its limits Natural Product Reports 2012 29:899-934 DOI:10.1039/c2np20034a PMID:22729238
- Krenske, E. H., Perry, E. W., Jerome, S. V., Maimone, T. J., Baran, P. S., Houk, K. N. Why a proximity-induced Diels-Alder reaction is so fast Organic Letters 2012 14:3016-3019 DOI:10.1021/ol301083q PMID:22630569 PMCID:PMC3426630
- Gutekunst, W. R., Baran, P. S. C-H functionalization logic in total synthesis Chemical Society Reviews 2011 40:1976-1991 DOI:10.1039/c0cs00182a PMID:21298176
- Seiple, I. B., Su, S., Young, I. S., Nakamura, A., Yamaguchi, J., Jorgensen, L., Rodriguez, R. A., O'Malley, D. P., Gaich, T., Kock, M., Baran, P. S. Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines Journal of the American Chemical Society 2011 133:14710-14726 DOI:10.1021/ja2047232 PMID:21861522 PMCID:PMC3173569
- Newhouse, T., Baran, P. S. If C-H bonds could talk: Selective C-H bond oxidation Angewandte Chemie-International Edition 2011 50:3362-3374 DOI:10.1002/anie.201006368 PMID:21413105 PMCID:PMC3980681
- Ji, Y. N., Brueckl, T., Baxter, R. D., Fujiwara, Y., Seiple, I. B., Su, S., Blackmond, D. G., Baran, P. S. Innate C-H trifluoromethylation of heterocycles Proceedings of the National Academy of Sciences of the United States of America 2011 108:14411-14415 DOI:10.1073/pnas.1109059108 PMID:21844378 PMCID:PMC3167544
- Jessing, M., Baran, P. S. Oxidative coupling of indoles with 3-oxindoles Heterocycles 2011 82:1739-1745 DOI:10.3987/com-10-s(e)127
- Fujiwara, Y., Domingo, V., Seiple, I. B., Gianatassio, R., Del Bel, M., Baran, P. S. Practical C-H functionalization of quinones with boronic acids Journal of the American Chemical Society 2011 133:3292-3295 DOI:10.1021/ja111152z PMID:21341741 PMCID:PMC3964812
- Lockner, J. W., Dixon, D. D., Risgaard, R., Baran, P. S. Practical radical cyclizations with arylboronic acids and trifluoroborates Organic Letters 2011 13:5628-5631 DOI:10.1021/ol2023505 PMID:21923108 PMCID:PMC3193542
- Shi, J., Manolikakes, G., Yeh, C. H., Guerrero, C. A., Shenvi, R. A., Shigehisa, H., Baran, P. S. Scalable synthesis of cortistatin A and related structures Journal of the American Chemical Society 2011 133:8014-8027 DOI:10.1021/ja202103e PMID:21539314 PMCID:PMC3119343
- Su, S., Rodriguez, R. A., Baran, P. S. Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B Journal of the American Chemical Society 2011 133:13922-13925 DOI:10.1021/ja206191g PMID:21846138 PMCID:PMC3164937
- Lin, D. W., Masuda, T., Biskup, M. B., Nelson, J. D., Baran, P. S. Synthesis-guided structure revision of the sarcodonin, sarcoviolin, and hydnellin natural product family Journal of Organic Chemistry 2011 76:1013-1030 DOI:10.1021/jo102228j PMID:21250718 PMCID:PMC3089814
- Cherney, E. C., Baran, P. S. Terpenoid-alkaloids: Their biosynthetic twist of fate and total synthesis Israel Journal of Chemistry 2011 51:391-405 DOI:10.1002/ijch.201100005 PMID:26207071 PMCID:PMC4508874
- Gutekunst, W. R., Baran, P. S. Total synthesis and structural revision of the piperarborenines via sequential cyclobutane C-H arylation Journal of the American Chemical Society 2011 133:19076-19079 DOI:10.1021/ja209205x PMID:22066860 PMCID:PMC3223735
- Foo, K., Newhouse, T., Mori, I., Takayama, H., Baran, P. S. Total synthesis guided structure elucidation of (+)-psychotetramine Angewandte Chemie-International Edition 2011 50:2716-2719 DOI:10.1002/anie.201008048 PMID:21387473 PMCID:PMC3365487
- Gaich, T., Baran, P. S. Aiming for the ideal synthesis Journal of Organic Chemistry 2010 75:4657-4673 DOI:10.1021/jo1006812 PMID:20540516
- Seiple, I. B., Su, S., Rodriguez, R. A., Gianatassio, R., Fujiwara, Y., Sobel, A. L., Baran, P. S. Direct C-H arylation of electron-deficient heterocycles with arylboronic acids Journal of the American Chemical Society 2010 132:13194-13196 DOI:10.1021/ja1066459 PMID:20812741 PMCID:PMC2946225
- Schultz, A. W., Lewis, C. A., Luzung, M. R., Baran, P. S., Moore, B. S. Functional characterization of the cyclomarin/cyclomarazine prenyltransferase cymd directs the biosynthesis of unnatural cyclic peptides Journal of Natural Products 2010 73:373-377 DOI:10.1021/np9006876 PMID:20055491 PMCID:PMC2846197
- Newhouse, T., Lewis, C. A., Eastman, K. J., Baran, P. S. Scalable total syntheses of N-linked tryptamine dimers by direct indole-aniline coupling: Psychotrimine and kapakahines B and F Journal of the American Chemical Society 2010 132:7119-7137 DOI:10.1021/ja1009458 PMID:20426477 PMCID:PMC2874090
- Cipres, A., O'Malley, D. P., Li, K., Finlay, D., Baran, P. S., Vuori, K. Sceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines ACS Chemical Biology 2010 5:195-202 DOI:10.1021/cb900240k PMID:20030414 PMCID:PMC2825093
- Sella, E., Weinstain, R., Erez, R., Burns, N. Z., Baran, P. S., Shabat, D. Sulfhydryl-based dendritic chain reaction Chemical Communications 2010 46:6575-6577 DOI:10.1039/c0cc02195d PMID:20714571
- Schallenberger, M. A., Newhouse, T., Baran, P. S., Romesberg, F. E. The psychotrimine natural products have antibacterial activity against gram-positive bacteria and act via membrane disruption Journal of Antibiotics 2010 63:685-687 DOI:10.1038/ja.2010.107 PMID:20924383 PMCID:PMC3979425
- Chen, K., Ishihara, Y., Galan, M. M., Baran, P. S. Total synthesis of eudesmane terpenes: cyclase phase Tetrahedron 2010 66:4738-4744 DOI:10.1016/j.tet.2010.02.088
- Seiple, I. B., Su, S., Young, I. S., Lewis, C. A., Yamaguchi, J., Baran, P. S. Total synthesis of palau'amine Angewandte Chemie-International Edition 2010 49:1095-1098 DOI:10.1002/anie.200907112 PMID:20041464 PMCID:PMC3367661
- Ishihara, Y., Baran, P. S. Two-phase terpene total synthesis: historical perspective and application to the Taxol problem Synlett 2010 1733-1745 DOI:10.1055/s-0030-1258123
- Eastman, K., Baran, P. S. A simple method for the direct arylation of indoles Tetrahedron 2009 65:3149-3154 DOI:10.1016/j.tet.2008.09.028
- Krawczuk, P. J., Schone, N., Baran, P. S. A synthesis of the carbon skeleton of maoecrystal v Organic Letters 2009 11:4774-4776 DOI:10.1021/ol901963v PMID:19795876 PMCID:PMC2783297
- Weinstain, R., Baran, P. S., Shabat, D. Activity-linked labeling of enzymes by self-immolative polymers Bioconjugate Chemistry 2009 20:1783-1791 DOI:10.1021/bc9002037 PMID:19689155
- Hafensteiner, B. D., Escribano, M., Petricci, E., Baran, P. S. An improved synthesis of alpha,beta-unsaturated nitrones relevant to the stephacidins and analogs thereof Bioorganic & Medicinal Chemistry Letters 2009 19:3808-3810 DOI:10.1016/j.bmcl.2009.04.045 PMID:19423345 PMCID:PMC2709696
- Shenvi, R. A., O'Malley, D. P., Baran, P. S. Chemoselectivity: The mother of invention in total synthesis Accounts of Chemical Research 2009 42:530-541 DOI:10.1021/ar800182r PMID:19182997 PMCID:PMC2765532
- Luzung, M. R., Lewis, C. A., Baran, P. S. Direct, chemoselective N-tert-prenylation of indoles by C-H functionalization Angewandte Chemie-International Edition 2009 48:7025-7029 DOI:10.1002/anie.200902761 PMID:19701955 PMCID:PMC2886517
- Newhouse, T., Lewis, C. A., Baran, P. S. Enantiospecific total syntheses of kapakahines B and F Journal of the American Chemical Society 2009 131:6360-6361 DOI:10.1021/ja901573x PMID:19374357
- Young, I. S., Baran, P. S. Protecting-group-free synthesis as an opportunity for invention Nature Chemistry 2009 1:193-205 DOI:10.1038/nchem.216 PMID:21378848
- Burns, N. Z., Baran, P. S., Hoffmann, R. W. Redox economy in organic synthesis Angewandte Chemie-International Edition 2009 48:2854-2867 DOI:10.1002/anie.200806086 PMID:19294720
- Burns, N. Z., Krylova, I. N., Hannoush, R. N., Baran, P. S. Scalable total synthesis and biological evaluation of haouamine a and its atropisomer Journal of the American Chemical Society 2009 131:9172-9173 DOI:10.1021/ja903745s PMID:19530671 PMCID:PMC2740483
- Shi, J., Shigehisa, H., Guerrero, C. A., Shenvi, R. A., Li, C. C., Baran, P. S. Stereodivergent synthesis of 17-alpha and 17-beta-alpharyl steroids: Application and biological evaluation of D-ring cortistatin analogues Angewandte Chemie-International Edition 2009 48:4328-4331 DOI:10.1002/anie.200901116 PMID:19434636 PMCID:PMC3495592
- Chen, K., Eschenmoser, A., Baran, P. S. Strain release in C-H bond activation? Angewandte Chemie-International Edition 2009 48:9705-9708 DOI:10.1002/anie.200904474 PMID:19937877 PMCID:PMC2879134
- Newhouse, T., Baran, P. S., Hoffmann, R. W. The economies of synthesis Chemical Society Reviews 2009 38:3010-3021 DOI:10.1039/b821200g PMID:19847337 PMCID:PMC2880393
- Perry-Feigenbaum, R., Baran, P. S., Shabat, D. The pyridinone-methide elimination Organic & Biomolecular Chemistry 2009 7:4825-4828 DOI:10.1039/b915265b PMID:19907770
- Chen, K., Baran, P. S. Total synthesis of eudesmane terpenes by site-selective C-H oxidations Nature 2009 459:824-828 DOI:10.1038/nature08043 PMID:19440196
- Burns, N. Z., Jessing, M., Baran, P. S. Total synthesis of haouamine A: The indeno-tetrahydropyridine core Tetrahedron 2009 65:6600-6610 DOI:10.1016/j.tet.2009.05.075 PMID:20161191 PMCID:PMC2728496
- Maimone, T. J., Shi, J., Ashida, S., Baran, P. S. Total synthesis of vinigrol Journal of the American Chemical Society 2009 131:17066-17067 DOI:10.1021/ja908194b PMID:19877628 PMCID:PMC2787793
- Chen, K., Richter, J. M., Baran, P. S. 1,3-diol synthesis via controlled, radical-mediated C-H functionalization Journal of the American Chemical Society 2008 130:7247-7249 DOI:10.1021/ja802491q PMID:18481847
- Maimone, T. J., Voica, A. F., Baran, P. S. A concise approach to vinigrol Angewandte Chemie-International Edition 2008 47:3054-3056 DOI:10.1002/anie.200800167 PMID:18338349
- Richter, J. M., Ishihara, Y., Masuda, T., Whitefield, B. W., Llamas, T., Pohjakallio, A., Baran, P. S. Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach Journal of the American Chemical Society 2008 130:17938-17954 DOI:10.1021/ja806981k PMID:19035635 PMCID:PMC2634302
- DeMartino, M. P., Chen, K., Baran, P. S. Intermolecular enolate heterocoupling: Scope, mechanism, and application Journal of the American Chemical Society 2008 130:11546-11560 DOI:10.1021/ja804159y PMID:18680297
- Burns, N. Z., Baran, P. S. On the origin of the haouamine alkaloids Angewandte Chemie-International Edition 2008 47:205-208 DOI:10.1002/anie.200704576 PMID:18038444
- Shenvi, R. A., Guerrero, C. A., Shi, J., Li, C. C., Baran, P. S. Synthesis of (+)-cortistatin A Journal of the American Chemical Society 2008 130:7241-7243 DOI:10.1021/ja8023466 PMID:18479104 PMCID:PMC2652360
- Yamaguchi, J., Seiple, I. B., Young, I. S., O'Malley, D. P., Maue, M., Baran, P. S. Synthesis of 1,9-dideoxy-pre-axinellamine Angewandte Chemie-International Edition 2008 47:3578-3580 DOI:10.1002/anie.200705913 PMID:18357598
- Su, S., Seiple, I. B., Young, I. S., Baran, P. S. Total syntheses of (+/-)-massadine and massadine chloride Journal of the American Chemical Society 2008 130:16490-16491 DOI:10.1021/ja8074852 PMID:19049446 PMCID:PMC2913575
- O'Malley, D. P., Yamaguchi, J., Young, I. S., Seiple, I. B., Baran, P. S. Total synthesis of (+/-)-axinellamines A and B Angewandte Chemie-International Edition 2008 47:3581-3583 DOI:10.1002/anie.200801138 PMID:18357612
- Newhouse, T., Baran, P. S. Total synthesis of (+/-)-psychotrimine Journal of the American Chemical Society 2008 130:10886-10887 DOI:10.1021/ja8042307 PMID:18656919
- Baran, P. S.*, Maimone, T. J.* Organic chemistry: A tuxedo for iodine atoms Nature 2007 445:826-827 DOI:10.1038/445826a PMID:17314962 (* = equal contribution)
- Grube, A., Immel, S., Baran, P. S., Kock, M. Massadine chloride: A biosynthetic precursor of massadine and stylissadine Angewandte Chemie-International Edition 2007 46:6721-6724 DOI:10.1002/anie.200701935 PMID:17685369
- Maimone, T. J., Baran, P. S. Modern synthetic efforts toward biologically active terpenes Nature Chemical Biology 2007 3:396-407 DOI:10.1038/nchembio.2007.1 PMID:17576427
- Richter, J. M., Whitefield, B. W., Maimone, T. J., Lin, D. W., Castroviejo, M. P., Baran, P. S. Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: Total synthesis of acremoauxin A and oxazinin 3 Journal of the American Chemical Society 2007 129:12857-12869 DOI:10.1021/ja074392m PMID:17900115 PMCID:PMC2631414
- Kock, M., Grube, A., Seiple, I. B., Baran, P. S. The pursuit of palau'amine Angewandte Chemie-International Edition 2007 46:6586-6594 DOI:10.1002/anie.200701798 PMID:17724780
- O'Malley, D. P., Li, K., Maue, M., Zografos, A. L., Baran, P. S. Total synthesis of dimeric pyrrole-imidazole alkaloids: Sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton Journal of the American Chemical Society 2007 129:4762-4775 DOI:10.1021/ja069035a PMID:17375928
- Baran, P. S.*, Maimone, T. J.*, Richter, J. M. Total synthesis of marine natural products without using protecting groups Nature 2007 446:404-408 DOI:10.1038/nature05569 PMID:17377577 (* = equal contribution)
- Baran, P. S.*, Hafensteiner, B. D.*, Ambhaikar, N. B., Guerrero, C. A., Gallagher, J. D. Enantioselective total synthesis of avrainvillamide and the stephacidins Journal of the American Chemical Society 2006 128:8678-8693 DOI:10.1021/ja061660s PMID:16802835 (* = equal contribution)
- Baran, P. S.*, DeMartino, M. P.* Intermolecular oxidative enolate heterocoupling Angewandte Chemie-International Edition 2006 45:7083-7086 DOI:10.1002/anie.200603024 PMID:17009377 (* = equal contribution)
- Northrop, B. H., O'Malley, D. P., Zografos, A. L., Baran, P. S., Houk, K. N. Mechanism of the vinylcyclobutane rearrangement of sceptrin to ageliferin and nagelamide E Angewandte Chemie-International Edition 2006 45:4126-4130 DOI:10.1002/anie.200600514 PMID:16703636
- Baran, P. S., Shenvi, R. A., Nguyen, S. A. One-step synthesis of 4,5-disubstituted pyrimidines using commercially available and inexpensive reagents Heterocycles 2006 70:581-586 DOI:10.3987/COM-06-S(W)27
- Baran, P. S., Ambhaikar, N. B., Guerrero, C. A., Hafensteiner, B. D., Lin, D. W., Richter, J. M. Oxidative C-C bond formation in heterocyclic chemistry Arkivoc 2006 310-325
- Baran, P. S., Li, K., O'Malley, D. R., Mitsos, C. Short, enantioselective total synthesis of sceptrin and ageliferin by programmed oxaquadricyclane fragmentation Angewandte Chemie-International Edition 2006 45:249-252 DOI:10.1002/anie.200503374 PMID:16317782
- Baran, P. S., Shenvi, R. A. Total synthesis of (+/-)-chartelline C Journal of the American Chemical Society 2006 128:14028-14029 DOI:10.1021/ja0659673 PMID:17061876
- Baran, P. S.*, Burns, N. Z.* Total synthesis of (+/-)-haouamine A Journal of the American Chemical Society 2006 128:3908-3909 DOI:10.1021/ja0602997 PMID:16551088 (* = equal contribution)
- Baran, P. S., Shenvi, R. A., Mitsos, C. A. A remarkable ring contraction en route to the chartelline alkaloids Angewandte Chemie-International Edition 2005 44:3714-3717 DOI:10.1002/anie.200500522 PMID:15900528
- Baran, P. S.*, Richter, J. M.*, Lin, D. W. Direct coupling of pyrroles with carbonyl compounds: Short enantioselective synthesis of (S)-ketorolac Angewandte Chemie-International Edition 2005 44:609-612 DOI:10.1002/anie.200462048 PMID:15584071 (* = equal contribution)
- Baran, P. S.*, Richter, J. M.* Enantioselective total syntheses of welwitindolinone A and fischerindoles I and G Journal of the American Chemical Society 2005 127:15394-15396 DOI:10.1021/ja056171r PMID:16262402 (* = equal contribution)
- Baran, P. S.*, Guerrero, C. A.*, Ambhaikar, N. B., Hafensteiner, B. D. Short, enantioselective total synthesis of stephacidin A Angewandte Chemie-International Edition 2005 44:606-609 DOI:10.1002/anie.200461864 PMID:15586393 (* = equal contribution)
- Baran, P. S.*, Guerrero, C. A.*, Hafensteiner, B. D., Ambhaikar, N. B. Total synthesis of avrainvillamide (CJ-17,665) and stephacidin B Angewandte Chemie-International Edition 2005 44:3892-3895 DOI:10.1002/anie.200500655 PMID:15900526 (* = equal contribution)
- Baran, P. S.*, Richter, J. M.* Direct coupling of indoles with carbonyl compounds: Short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families Journal of the American Chemical Society 2004 126:7450-7451 DOI:10.1021/ja047874w PMID:15198586 (* = equal contribution)
- Baran, P. S.*, O'Malley, D. P.*, Zografos, A. L. Sceptrin as a potential biosynthetic precursor to complex pyrrole-imidazole alkaloids: The total synthesis of ageliferin Angewandte Chemie-International Edition 2004 43:2674-2677 DOI:10.1002/anie.200453937 PMID:18629987 (* = equal contribution)
- Baran, P. S., Zografos, A. L., O'Malley, D. P. Short total synthesis of (+/-)-sceptrin Journal of the American Chemical Society 2004 126:3726-3727 DOI:10.1021/ja049648s PMID:15038721
- Baran, P. S., Guerrero, C. A., Corey, E. J. Short, enantioselective total synthesis of okaramine n Journal of the American Chemical Society 2003 125:5628-5629 DOI:10.1021/ja034491+ PMID:12733890
- Baran, P. S., Guerrero, C. A., Corey, E. J. The first method for protection-deprotection of the indole 2,3-pi bond Organic Letters 2003 5:1999-2001 DOI:10.1021/ol034634x PMID:12762706
- Baran, P. S., Corey, E. J. A short synthetic route to (+)-austamide, (+)-deoxyisoaustamide, and (+)-hydratoaustamide from a common precursor by a novel palladium-mediated indole -> dihydroindoloazocine cyclization Journal of the American Chemical Society 2002 124:7904-7905 DOI:10.1021/ja026663t PMID:12095326
-
Nicolaou, K. C., Montagnon, T., Baran, P. S.
HIO3 and I2O5: mild and selective alternative reagents to IBX for the dehydrogenation of aldehydes and ketones
Angewandte Chemie-International Edition
2002
41:1386-1389
DOI:10.1002/1521-3773(20020415)41:8<1386::aid-anie1386>3.0.co;2-v
PMID:19750773
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Sugita, K.
Iodine(V) reagents in organic synthesis. Part 1. Synthesis of polycyclic heterocycles via Dess-Martin periodinane-mediated cascade cyclization: Generality, scope, and mechanism of the reaction
Journal of the American Chemical Society
2002
124:2212-2220
DOI:10.1021/ja012124x
PMID:11878975
(* = equal contribution)
-
Nicolaou, K. C., Sugita, K., Baran, P. S., Zhong, Y. L.
Iodine(V) reagents in organic synthesis. Part 2. Access to complex molecular architectures via Dess-Martin periodinane-generated o-imidoquinones
Journal of the American Chemical Society
2002
124:2221-2232
DOI:10.1021/ja012125p
PMID:11878976
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Barluenga, S., Hunt, K. W., Kranich, R., Vega, J. A.
Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: Generality, scope, and mechanism
Journal of the American Chemical Society
2002
124:2233-2244
DOI:10.1021/ja012126h
PMID:11878977
(* = equal contribution)
-
Nicolaou, K. C., Montagnon, T., Baran, P. S., Zhong, Y. L.
Iodine(V) reagents in organic synthesis. Part 4. O-iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes
Journal of the American Chemical Society
2002
124:2245-2258
DOI:10.1021/ja012127+
PMID:11878978
-
Nicolaou, K. C., Montagnon, T., Baran, P. S.
Modulation of the reactivity profile of IBX by ligand complexation: Ambient temperature dehydrogenation of aldehydes and ketones to alpha,beta-unsaturated carbonyl compounds
Angewandte Chemie-International Edition
2002
41:993-996
DOI:10.1002/1521-3773(20020315)41:6<993::aid-anie993>3.0.co;2-u
PMID:12491291
-
Nicolaou, K. C., Montagnon, T., Ulven, T., Baran, P. S., Zhong, Y. L., Sarabia, F.
Novel chemistry of alpha-tosyloxy ketones: Applications to the solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries
Journal of the American Chemical Society
2002
124:5718-5728
DOI:10.1021/ja012146j
PMID:12010045
-
Nicolaou, K. C.*, Baran, P. S.*
The CP molecule labyrinth: a paradigm of how endeavors in total synthesis lead to discoveries and inventions in organic synthesis
Angewandte Chemie-International Edition
2002
41:2678-2720
DOI:10.1002/1521-3773(20020802)41:15<2678::aid-anie2678>3.0.co;2-v
PMID:12203464
(* = equal contribution)
-
Nicolaou, K. C., Jung, J., Yoon, W. H., Fong, K. C., Choi, H. S., He, Y., Zhong, Y. L., Baran, P. S.
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo 4.3.1 key building blocks
Journal of the American Chemical Society
2002
124:2183-2189
DOI:10.1021/ja012010l
PMID:11878972
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Fong, K. C., Choi, K. S.
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy
Journal of the American Chemical Society
2002
124:2190-2201
DOI:10.1021/ja012011d
PMID:11878973
(* = equal contribution)
-
Nicolaou, K. C., Zhong, Y. L., Baran, P. S., Jung, J., Choi, H. S., Yoon, W. H.
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 3. Completion and synthesis of advanced analogues
Journal of the American Chemical Society
2002
124:2202-2211
DOI:10.1021/ja0120126
PMID:11878974
-
Nicolaou, K. C.*, Baran, P. S.*, Kranich, R., Zhong, Y. L., Sugita, K., Zou, N.
Mechanistic studies of periodinane-mediated reactions of anilides and related systems
Angewandte Chemie-International Edition
2001
40:202-206
DOI:10.1002/1521-3773(20010105)40:1<202::aid-anie202>3.0.co;2-3
PMID:11169713
(* = equal contribution)
-
Nicolaou, K. C., Sugita, K., Baran, P. S., Zhong, Y. L.
New synthetic technology for the construction of N-containing quinones and derivatives thereof: Total synthesis of epoxyquinomycin B
Angewandte Chemie-International Edition
2001
40:207-210
DOI:10.1002/1521-3773(20010105)40:1<207::aid-anie207>3.3.co;2-b
PMID:11169714
-
Nicolaou, K. C., Zhong, Y. L., Baran, P. S., Sugita, K.
Rapid access to complex molecular architectures via o-Azaquinones
Angewandte Chemie-International Edition
2001
40:2145-2149
DOI:10.1002/1521-3773(20010601)40:11<2145::aid-anie2145>3.0.co;2-m
PMID:11433472
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L.
Selective oxidation at carbon adjacent to aromatic systems with IBX
Journal of the American Chemical Society
2001
123:3183-3185
DOI:10.1021/ja004218x
PMID:11457049
(* = equal contribution)
- MacMahon, S., Fong, R., 2nd, Baran, P. S., Safonov, I., Wilson, S. R., Schuster, D. I. Synthetic approaches to a variety of covalently linked porphyrin-fullerene hybrids Journal of Organic Chemistry 2001 66:5449-5455 DOI:10.1021/jo010317x PMID:11485469
-
Nicolaou, K. C., Zhong, Y. L., Baran, P. S.
A new method for the one-step synthesis of alpha,beta-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds
Journal of the American Chemical Society
2000
122:7596-7597
DOI:10.1021/ja001825b
-
Nicolaou, K. C., Vassilikogiannakis, G., Simonsen, K. B., Baran, P. S., Zhong, Y. L., Vidali, V. P., Pitsinos, E. N., Couladouros, E. A.
Biomimetic total synthesis of bisorbicillinol, bisorbibutenolide, trichodimerol, and designed analogues of the bisorbicillinoids
Journal of the American Chemical Society
2000
122:3071-3079
DOI:10.1021/ja9942843
-
Nicolaou, K. C., Vassilikogiannakis, G., Kranich, R., Baran, P. S., Zhong, Y. L., Natarajan, S.
New synthetic technology for the mild and selective one-carbon homologation of hindered aldehydes in the presence of ketones
Organic Letters
2000
2:1895-1898
DOI:10.1021/ol000102u
PMID:10891185
-
Nicolaou, K. C., Zhong, Y. L., Baran, P. S.
New synthetic technology for the rapid construction of novel heterocycles. Part 1. The reaction of Dess-Martin periodinane with anilides and related compounds
Angewandte Chemie-International Edition
2000
39:622-625
DOI:10.1002/(sici)1521-3773(20000204)39:3<622::aid-anie622>3.3.co;2-2
PMID:10671278
-
Nicolaou, K. C., Zhong, Y. L., Baran, P. S.
New synthetic technology for the rapid construction of novel heterocycles. Part 2. The reaction of IBX with anilides and related compounds
Angewandte Chemie-International Edition
2000
39:625-628
DOI:10.1002/(sici)1521-3773(20000204)39:3<625::aid-anie625>3.0.co;2-#
PMID:10671279
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Vega, J. A.
Novel IBX-mediated processes for the synthesis of amino sugars and libraries thereof
Angewandte Chemie-International Edition
2000
39:2525-2529
DOI:10.1002/1521-3773(20000717)39:14<2525::aid-anie2525>3.0.co;2-1
PMID:10941125
(* = equal contribution)
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L.
Novel solution- and solid-phase chemistry of α-sulfonated ketones applicable to combinatorial chemistry
Journal of the American Chemical Society
2000
122:10246-10248
DOI:10.1021/ja002768p
(* = equal contribution)
-
Nicolaou, K. C., Jung, J. K., Yoon, W. H., He, Y., Zhong, Y. L., Baran, P. S.
The absolute configuration and asymmetric total synthesis of the CP molecules (CP-263,114 and CP-225,917, phomoidrides B and A)
Angewandte Chemie-International Edition
2000
39:1829-1832
DOI:10.1002/(sici)1521-3773(20000515)39:10<1829::aid-anie1829>3.0.co;2-6
PMID:10934377
-
Nicolaou, K. C., Vourloumis, D., Winssinger, N., Baran, P. S.
The art and science of total synthesis at the dawn of the twenty-first century
Angewandte Chemie-International Edition
2000
39:44-122
DOI:10.1002/(sici)1521-3773(20000103)39:1<44::aid-anie44>3.3.co;2-c
PMID:10649349
-
Nicolaou, K. C.*, Baran, P. S.*, Jautelat, R., He, Y., Fong, K. C., Choi, H. S., Yoon, W. H., Zhong, Y. L.
A novel route to the fused maleic anhydride moiety of CP molecules
Angewandte Chemie-International Edition
1999
38:549-552
DOI:10.1002/(sici)1521-3773(19990215)38:4<549::aid-anie549>3.0.co;2-o
(* = equal contribution)
-
Nicolaou, K. C., Simonsen, K. B., Vassilikogiannakis, G., Baran, P. S., Vidali, V. P., Pitsinos, E. N., Couladouros, E. A.
Biomimetic explorations towards the bisorbicillinoids: total synthesis of bisorbicillinol, bisorbibutenolide, and trichodimerol
Angewandte Chemie-International Edition
1999
38:3555-3559
DOI:10.1002/(sici)1521-3773(19991203)38:23<3555::aid-anie3555>3.0.co;2-z
PMID:10602241
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Choi, H. S., Fong, K. C., He, Y., Yoon, W. H.
New synthetic technology for the synthesis of hindered α-diazoketones via acyl mesylates
Organic Letters
1999
1:883-886
DOI:10.1021/ol990790l
PMID:10823217
(* = equal contribution)
-
Nicolaou, K. C.*, He, Y.*, Fong, K. C., Yoon, W. H., Choi, H. S., Zhong, Y. L., Baran, P. S.
Novel strategies to construct the γ-hydroxy lactone moiety of the CP molecules. Synthesis of the CP-225,917 core skeleton
Organic Letters
1999
1:63-66
DOI:10.1021/ol990551y
PMID:10822534
(* = equal contribution)
- Baran, P. S., Khan, A. U., Schuster, D. I., Wilson, S. R. Some photophysical properties of nanotubes Fullerene Science and Technology 1999 7:921-925 DOI:10.1080/10641229909351388
-
Nicolaou, K. C., Jautelat, R., Vassilikogiannakis, G., Baran, P. S., Simonsen, K. B.
Studies towards trichodimerol: Novel cascade reactions and polycyclic frameworks
Chemistry-a European Journal
1999
5:3651-3665
DOI:10.1002/(sici)1521-3765(19991203)5:12<3651::aid-chem3651>3.3.co;2-p
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Fong, K. C., He, Y., Yoon, W. H., Choi, H. S.
Total synthesis of the CP molecules CP-225,917 and CP-263,114. Part 2: Evolution of the final strategy
Angewandte Chemie-International Edition
1999
38:1676-1678
DOI:10.1002/(sici)1521-3773(19990601)38:11<1676::aid-anie1676>3.0.co;2-t
(* = equal contribution)
-
Nicolaou, K. C.*, Baran, P. S.*, Zhong, Y. L., Choi, H. S., Yoon, W. H., He, Y., Fong, K. C.
Total synthesis of the CP molecules CP-263,114 and CP-225,917. Part 1: Synthesis of key intermediates and intelligence gathering
Angewandte Chemie-International Edition
1999
38:1669-1675
DOI:10.1002/(sici)1521-3773(19990601)38:11<1669::aid-anie1669>3.0.co;2-d
(* = equal contribution)
- Schuster, D. I.*, Baran, P. S.*, Hatch, R. K., Khan, A. U., Wilson, S. R. The role of singlet oxygen in the photochemical formation of c60o Chemical Communications 1998 2493-2494 DOI:10.1039/a806603e (* = equal contribution)
- Baran, P. S., Monaco, R. R., Khan, A. U., Schuster, D. I., Wilson, S. R. Synthesis and cation-mediated electronic interactions of two novel classes of porphyrin-fullerene hybrids Journal of the American Chemical Society 1997 119:8363-8364 DOI:10.1021/ja970486s
- Safonov, I. G., Baran, P. S., Schuster, D. I. Synthesis and photophysics of a novel porphyrin-c-60 hybrid Tetrahedron Letters 1997 38:8133-8136 DOI:10.1016/s0040-4039(97)10184-8
