Publication list

publication_uri type publication_title year doi pmid journal_uri
http://vivo.scripps.edu/individual/e2n182131 AcademicArticle INCB24360 (epacadostat), a highly potent and selective indoleamine-2,3-dioxygenase 1 (ID01) inhibitor for immunooncology 2017 10.1021/acsmedchemlett.6b00391 28523098 http://vivo.scripps.edu/individual/endnote225139
http://vivo.scripps.edu/individual/e2n313116 AcademicArticle Discovery of matrix metalloproteases selective and activated peptide-doxorubicin prodrugs as anti-tumor agents 2010 10.1016/j.bmcl.2009.12.084 20060717 http://vivo.scripps.edu/individual/endnote119710
http://vivo.scripps.edu/individual/e2n295731 AcademicArticle Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity 2010 10.1182/blood-2009-09-246124 20197554 http://vivo.scripps.edu/individual/endnote304227
http://vivo.scripps.edu/individual/e2n209127 AcademicArticle Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors 2010 10.1158/1535-7163.mct-09-0628 20124451 http://vivo.scripps.edu/individual/endnote285320
http://vivo.scripps.edu/individual/e2n63516 AcademicArticle Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists 2009 10.1021/jm900301y 19552437 http://vivo.scripps.edu/individual/endnote266962
http://vivo.scripps.edu/individual/e2n298838 AcademicArticle In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists 2009 10.1021/jm900302q 19552436 http://vivo.scripps.edu/individual/endnote266962
http://vivo.scripps.edu/individual/e2n42138 AcademicArticle Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model 2009 10.1021/jm900518f 19507862 http://vivo.scripps.edu/individual/endnote266962
http://vivo.scripps.edu/individual/e2n239424 AcademicArticle Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines 2008 10.1016/j.bmcl.2007.11.012 18037290 http://vivo.scripps.edu/individual/endnote119710
http://vivo.scripps.edu/individual/e2n179531 AcademicArticle Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic 2006 10.1021/jm0600904 16789735 http://vivo.scripps.edu/individual/endnote266962
http://vivo.scripps.edu/individual/e2n162651 AcademicArticle Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: Synthesis and structure-activity relationships of a peptide scaffold 2006 10.1016/j.bmc.2006.05.032 16769216 http://vivo.scripps.edu/individual/endnote193708
http://vivo.scripps.edu/individual/e2n96391 AcademicArticle Structural insights into the design of nonpeptidic isothiazolidinone-containing inhibitors of protein-tyrosine phosphatase 1B 2006 10.1074/jbc.M607913200 17028182 http://vivo.scripps.edu/individual/endnote308813
http://vivo.scripps.edu/individual/e2n238392 AcademicArticle Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics 2006 10.1074/jbc.M606873200 16916797 http://vivo.scripps.edu/individual/endnote308813
http://vivo.scripps.edu/individual/e2n237588 AcademicArticle Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics 2005 10.1021/jm.0504555 16220970 http://vivo.scripps.edu/individual/endnote266962
http://vivo.scripps.edu/individual/e2n27552 AcademicArticle Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth doxorubicin with less toxicity 2005 10.1158/1535-7163.mct-05-0006 15897239 http://vivo.scripps.edu/individual/endnote285320
http://vivo.scripps.edu/individual/e2n148161 AcademicArticle Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3 2004 10.1016/j.bmcl.2003.11.008 14698155 http://vivo.scripps.edu/individual/endnote119710
http://vivo.scripps.edu/individual/e2n93619 AcademicArticle Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3 2002 10.1021/jm0201722 12431051 http://vivo.scripps.edu/individual/endnote266962
http://vivo.scripps.edu/individual/e2n175104 Chapter New roads to molecular complexity 2000
http://vivo.scripps.edu/individual/endnote390117 AcademicArticle Total synthesis of selected natural products 1997 10.1351/pac199769030413 http://vivo.scripps.edu/individual/endnote313708
http://vivo.scripps.edu/individual/endnote340212 AcademicArticle An olefin metathesis based strategy for the construction of the JKL, OPQ, and UVW ring systems of maitotoxin 1996 10.1021/ja962862z http://vivo.scripps.edu/individual/endnote181842
http://vivo.scripps.edu/individual/endnote335374 AcademicArticle Synthesis of zaragozic acid A/squalestatin S1 1995 10.1002/chem.19950010712 http://vivo.scripps.edu/individual/endnote203654
http://vivo.scripps.edu/individual/endnote281833 AcademicArticle Zaragozic-acid-A squalestatin-S1 - synthetic and retrosynthetic studies 1994 10.1002/anie.199421841 http://vivo.scripps.edu/individual/endnote319084
http://vivo.scripps.edu/individual/endnote131855 AcademicArticle Total synthesis of zaragozic-acid-A squalestatin-S1 1994 10.1002/anie.199421901 http://vivo.scripps.edu/individual/endnote319084
http://vivo.scripps.edu/individual/endnote274788 AcademicArticle Synthesis of the first fully functionalized core of the zaragozic acids squalestatins 1994 10.1002/anie.199421871 http://vivo.scripps.edu/individual/endnote319084
http://vivo.scripps.edu/individual/endnote191935 AcademicArticle Chemistry and biology of natural and designed enediynes 1993 10.1073/pnas.90.13.5881 8327459 http://vivo.scripps.edu/individual/endnote71945
http://vivo.scripps.edu/individual/e2n142699 AcademicArticle Synthesis of 2,3-dimethoxy-5-iodobenzoic acid 1991 10.1021/jo00018a048 http://vivo.scripps.edu/individual/endnote171323