Academic Article

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A structural hypothesis for bh4 responsiveness in patients with mild forms of hyperphenylalaninaemia and phenylketonuria
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
A structural model for cyanine dyes templated into the minor groove of DNA
A structural model for regulation of nhej by DNA-pkcs autophosphorylation
A structural model for the high-valent intermediate Q of methane monooxygenase from broken-symmetry density functional and electrostatics calculations
A structural model for the prostate disease marker, human prostate-specific antigen
A structural perspective of the sequence variability within botulinum neurotoxin subtypes a1-a4
A structural role of histidine 15 in human glutathione transferase M1-1, an amino acid residue conserved in class Mu enzymes
A structural snapshot of CYP2B4 in complex with paroxetine provides insights into ligand binding and clusters of conformational states
A structural view of evolutionary divergence
A structurally deviant member of the euplotes raikovi pheromone family: Er-23
A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union
A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor
A structure-activity study of nociceptin-(1-13)-peptide amide. Synthesis of analogues substituted in positions 0, 1, 3, 4 and 10
A structure-based approach to a synthetic vaccine for hiv-1
A structure-based assembly screen of protein cage libraries in living cells: experimentally repacking a protein-protein interface to recover cage formation in an assembly-frustrated mutant
A structure-based library approach to kinase inhibitors
A structure-guided approach to creating covalent FGFR inhibitors
A student team in a University of Michigan biomedical engineering design course constructs a microfluidic bioreactor for studies of zebrafish development
A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody
A study of genes that may modulate the expression of hereditary hemochromatosis: Transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (irp)-1 and-2, and hepcidin
A study of the alpha-transfer reaction in the 16-O + 16-O system at near-barrier energies
A study of the electron-paramagnetic resonance properties of single monoclinic crystals of bovine superoxide-dismutase
A study of the scope of the 4+2 cyclo-addition reactions of unactivated 1,3-oxazin-6-ones
A study of the specificity of the direct binding between bacteria and HLA antigens
A study on docking mode of HIV protease and their inhibitors
A subgroup-specific antigenic site in the G protein of respiratory syncytial virus forms a disulfide-bonded loop
A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation
A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of pseudomonas aeruginosa FabA
A substrate-based methodology that allows the regioselective control of the catalytic aminohydroxylation reaction