Scripps VIVO

Academic Article RDF

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• A novel α2/α4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors acting from the C-tail of an α subunit
• A novel β-peptidyl aminopeptidase (BapA) from strain 3-2W4 cleaves peptide bonds of synthetic β-tri- and β-dipeptides
• A novel, nonanaphylactogenic, bispecific IgE-CD3 antibody eliminates IgE1(+) B cells
• A novel, orally bioavailable nociceptin receptor antagonist, LY2940094, reduces ethanol self-administration and ethanol seeking in animal models
• A novel, quantitative bioassay for type I interferon using a recombinant indicator cell line
• A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests
• A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct
• A novel-approach to prevent the interference of protein a in immunoassays of enterotoxins
• A nuclear antigen associated with cell proliferation and blast transformation
• A nuclear gene of Chlamydomonas reinhardtii, Tba1, encodes a putative oxidoreductase required for translation of the chloroplast psbA mRNA
• A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid-hormone and retinoic acid receptors
• A nuclear import pathway for a protein involved in tRNA maturation
• A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
• A nucleophile-catalyzed cycloisomerization permits a concise synthesis of (+)-harziphilone
• A nucleoside transporter from Trypanosoma brucei involved in drug resistance
• A nucleosome bridging mechanism for activation of a maintenance DNA methyltransferase
• A nucleotide that enhances the charging of RNA minihelix sequence variants with alanine
• A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA
• A one-pot chemoenzymatic synthesis of (2S, 4R)-4-methylproline enables the first total synthesis of antiviral lipopeptide cavinafungin B
• A one-pot multistep approach to alpha-azido-phosphonate and phosphonothioate diesters: Key intermediates in the synthesis of haptens for the generation of antibody ligases
• A one-pot protocol for copper-mediated azide–alkyne cycloaddition using alkenyl triflate precursors
• A one-step synthesis of monoprotected polyethylene glycol ethers
• A P element with a novel fusion of reporters identifies regular, a C2H2 zinc-finger gene downstream of the circadian clock
• A p47-phox pseudogene carries the most common mutation causing p47-phox-deficient chronic granulomatous disease
• A pan-ALDH1A inhibitor induces necroptosis in ovarian cancer stem-like cells
• A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
• A pan-cyclophilin inhibitor, CRV431, decreases fibrosis and tumor development in chronic liver disease models
• A panel of igg1 b12 variants with selectively diminished or enhanced affinity for fc gamma receptors to define the role of effector functions in protection against hiv
• A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics
• A parallel approach to 7-(hetero)arylpyrazolo 1,5-a pyrimidin-5-ones

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