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A highly chemo- and stereoselective synthesis of beta-keto esters via a polymer-supported lipase catalyzed transesterfication
A highly concise preparation of O-deacetylated arylthioglycosides of N-acetyl-D-glucosamine from 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-alpha-D-glucopyranosyl chloride and aryl thiols or disulfides
A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
A highly conserved leucine in mammarenavirus matrix Z protein is required for Z interaction with the virus L polymerase and Z stability in cells harboring an active viral ribonucleoprotein
A highly conserved neutralizing epitope on group 2 influenza a viruses
A highly convergent strategy towards rapamycin - stereoselective construction of the c-8-c-18 fragment
A highly diastereo- and enantioselective synthesis of multisubstituted cyclopentanes with four chiral carbons by the organocatalytic domino Michael-Henry reaction
A highly diastereoselective and enantioselective synthesis of the top half of kijanolide
A highly effective nonpolar isostere of deoxyguanosine: synthesis, structure, stacking, and base pairing
A Highly Efficacious Carfentanil Vaccine That Blunts Opioid-Induced Antinociception and Respiratory Depression
A highly efficient aminohydroxylation process
A highly efficient and convergent reaction for the synthesis of bridgehead enone-containing polycyclic ring systems
A highly efficient azide-based protecting group for amines and alcohols
A highly efficient method for site-specific modification of unprotected peptides after chemical synthesis
A highly efficient multienzyme system for the one-step synthesis of a sialyl trisaccharide - insitu generation of sialic-acid and n-acetyllactosamine coupled with regeneration of udp-glucose, udp-galactose, and cmp-sialic acid
A highly enantioselective amino acid-catalyzed route to functionalized alpha-amino acids
A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives
A highly informative snp linkage panel for human genetic studies
A highly membrane-active peptide in Flock House virus: Implications for the mechanism of nodavirus infection
A highly pathogenic avian H7N9 influenza virus isolated from a human Is lethal in some ferrets infected via respiratory droplets
A highly polymorphic copy number variant in the NSF gene is associated with cocaine dependence
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model
A highly selective SF3B1-targeted splicing inhibitor reduces human CD34+ cell survival and self-renewal in acute myeloid leukemia
A highly sensitive plasma-based amyloid-β detection system through medium-changing and noise cancellation system for early diagnosis of the Alzheimer's disease
A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia
A highly specific metal-activated catalytic antibody
A highly stereoselective organocatalytic tandem aminoxylation/aza-Michael reaction for the synthesis of tetrahydro-1,2-oxazines
A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A
A highly stereoselective synthesis of 2-deoxy-beta-glycosides using 2-deoxy-2-iodo-glucopyranosyl acetate donors