Scripps VIVO

Academic Article RDF

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• A high-throughput assay for the identification of drugs against late-stage Plasmodium falciparum gametocytes
• A high-throughput cell-based Gaussia luciferase reporter assay for identifying modulators of fibulin-3 secretion
• A high-throughput ligand competition binding assay for the androgen receptor and other nuclear receptors
• A high-throughput method for Saccharomyces cerevisiae (yeast) ionomics
• A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis
• A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis
• A High-Throughput Screen for Chemicals that Increase the Lifespan of Caenorhabditis elegans
• A high-throughput screening compatible assay for activators and inhibitors of methionine sulfoxide reductase a
• A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchyrnal stem cells
• A high-throughput time-resolved fluorescence energy transfer assay to screen for modulators of RGS7/Gβ5/R7BP complex
• A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity
• A high-throughput-compatible FRET-based platform for identification and characterization of botulinum neurotoxin light chain modulators
• A high-yield purification procedure for alpha-chain and beta-chain of hla-dr antigens
• A higher degree of difficulty
• A highly acidic tyrosine 9 and a normally titrating tyrosine 212 contribute to the catalytic mechanism of human glutathione transferase A4-4
• A highly chemo- and stereoselective synthesis of beta-keto esters via a polymer-supported lipase catalyzed transesterfication
• A highly concise preparation of O-deacetylated arylthioglycosides of N-acetyl-D-glucosamine from 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-alpha-D-glucopyranosyl chloride and aryl thiols or disulfides
• A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs
• A highly conserved leucine in mammarenavirus matrix Z protein is required for Z interaction with the virus L polymerase and Z stability in cells harboring an active viral ribonucleoprotein
• A highly conserved neutralizing epitope on group 2 influenza a viruses
• A highly convergent strategy towards rapamycin - stereoselective construction of the c-8-c-18 fragment
• A highly diastereo- and enantioselective synthesis of multisubstituted cyclopentanes with four chiral carbons by the organocatalytic domino Michael-Henry reaction
• A highly diastereoselective and enantioselective synthesis of the top half of kijanolide
• A highly effective nonpolar isostere of deoxyguanosine: synthesis, structure, stacking, and base pairing
• A highly efficient aminohydroxylation process
• A highly efficient and convergent reaction for the synthesis of bridgehead enone-containing polycyclic ring systems
• A highly efficient azide-based protecting group for amines and alcohols
• A highly efficient method for site-specific modification of unprotected peptides after chemical synthesis
• A highly efficient multienzyme system for the one-step synthesis of a sialyl trisaccharide - insitu generation of sialic-acid and n-acetyllactosamine coupled with regeneration of udp-glucose, udp-galactose, and cmp-sialic acid
• A highly enantioselective amino acid-catalyzed route to functionalized alpha-amino acids

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