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A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation
A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents
A general amino acid synthesis enabled by innate radical cross-coupling
A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer
A general and efficient route for chemical aminoacylation of transfer RNAs
A general and highly efficient solid phase synthesis of oligosaccharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE)
A general and stereocontrolled total synthesis of leukotriene-b4 and analogs
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly
A general approach for the generation of orthogonal tRNAs
A general approach to sequence-controlled polymers using macrocyclic ring opening metathesis polymerization
A general approach to site-specific antibody drug conjugates
A general fragment-based approach to identify and optimize bioactive ligands targeting RNA
A general method for greatly improving the affinity of antibodies by using combinatorial libraries
A general method for insertion of functional proteins within proteins via combinatorial selection of permissive junctions
A general method for site-specific incorporation of unnatural amino acids into proteins
A general method to quantify quasi-equivalence in icosahedral viruses
A general protocol for addressing speciation of the active catalyst applied to ligand-accelerated enantioselective C(sp(3))-H bond arylation
A general purpose RNA-cleaving DNA enzyme
A general solid phase method for the preparation of diverse azapeptide probes directed against cysteine proteases
A general strategy for construction of both 2,6-cis- and 2,6-trans-disubstituted tetrahydropyrans: Substrate-controlled asymmetric total synthesis of (+)-scanlonenyne
A general strategy for the bacterial expression of amyloidogenic peptides using BCL-XL-1/2 fusions
A general strategy for the chemoenzymatic synthesis of asymmetrically branched N-glycans
A general strategy for the stereocontrolled preparation of diverse 8- and 9-membered Laurencia-type bromoethers
A general strategy for the synthesis of monohydroxyeicosatetraenoic acids - total synthesis of 5(s)-hydroxy-6(e),8,11,14(z)-eicosatetraenoic acid (5-hete) and 12(s)-hydroxy-5,8,14(z),10(e)-eicosatetraenoic acid (12-hete)
A general strategy for the total synthesis of the presumed lipoxin structures
A general strategy toward s-linked glycopeptides
A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(ii) tris-bipyridyl as an unusually efficient "warhead"
A general, polymer-supported acid catalyzed hetero-michael addition
A general-approach to enantiomerically pure methylcarbinols - asymmetric-synthesis of antibiotic (-)-a26771b and the wcr sex-pheromone