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A concise synthesis of (-)-aplyviolene facilitated by a strategic tertiary radical conjugate addition
A concise synthesis of (-)-hispidospermidin guided by a postulated biogenesis
A concise synthesis of fumagillol
A concise synthesis of single components of partially sulfated oligomannans
A concise synthesis of the fredericamycin-a DEF ring-system - 4+2 cycloaddition reactions of 1-aza-1,3-butadienes
A concise total synthesis of sespenine, a structurally unusual indole terpenoid from Streptomyces
A concise, biomimetic total synthesis of (+)-davanone
A concise, stereocontrolled total synthesis of rippertenol
A confetti trail of tumour evolution
A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies
A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform
A conjugate vaccine using enantiopure hapten imparts superior nicotine-binding capacity
A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses
A conservative isoleucine to leucine mutation causes major rearrangements and cold sensitivity in KlenTaq1 DNA polymerase
A conserved "hydrophobic staple motif" plays a crucial role in the refolding of human glutathione transferase P1-1
A conserved 'hydrophobic staple motif' plays a crucial role in the refolding of human glutathione transferase Pl-l
A conserved amphipathic helix is required for membrane tubule formation by Yop1p
A conserved basic patch and central kink in the nipah virus phosphoprotein multimerization domain are essential for polymerase function
A conserved family of prolyl-4-hydroxylases that modify HIF
A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from bacteroides thetaiotaomicron at 2.2 A resolution
A conserved hiv gp120 glycoprotein structure involved in chemokine receptor binding
A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase
A conserved mechanism for sulfonucleotide reduction
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction
A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions
A conserved MutS homolog connector domain interface interacts with MutL homologs
A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function
A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension
A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function