subject area of
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- A practical sulfenylation of 2,5-diketopiperazines Academic Article
- Activation of remote meta-C-H bonds assisted by an end-on template Academic Article
- An approach to mimicking the sesquiterpene cyclase phase by nickel-promoted diene/alkyne cooligomerization Academic Article
- Approaches to the chemical synthesis of the chlorosulfolipids Academic Article
- Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology Academic Article
- Caged [(18)F]FDG glycosylamines for imaging acidic tumor microenvironments using positron emission tomography Academic Article
- Chemoenzymatic synthesis of cholesteryl-6-O-tetradecanoyl-alpha-D-glucopyranoside: a product of host cholesterol efflux promoted by Helicobacter pylori Academic Article
- Constructing molecular complexity and diversity: Total synthesis of natural products of biological and medicinal importance Academic Article
- Data-driven synthesis of proteolysis-resistant peptide hormones Academic Article
- De novo synthesis of L-colitose and L-rhodinose building blocks Academic Article
- Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors Academic Article
- Design, synthesis and evaluation of 2,5-diketopiperazines as inhibitors of the MDM2-p53 interaction Academic Article
- Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions Academic Article
- Discovery and optimization of a series of pyrimidine-based phosphodiesterase 10A (PDE10A) inhibitors through fragment screening, structure-based design, and parallel synthesis Academic Article
- Dosage delivery of sensitive reagents enables glove-box-free synthesis Academic Article
- Dynamic covalent side-chain cross-links via intermolecular oxime or hydrazone formation from bifunctional peptides and simple organic linkers Academic Article
- Editorial overview: Synthetic biomolecules Academic Article
- Efficient and stereoselective synthesis of alpha(2 -> 9) oligosialic acids: From monomers to dodecamers Academic Article
- Enantioselective Heck arylations of acyclic alkenyl alcohols using a redox-relay strategy Academic Article
- Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines Academic Article
- Functionalized olefin cross-coupling to construct carbon-carbon bonds Academic Article
- Gas extrusion in natural products total synthesis Academic Article
- Glycocalyx scaffolding with synthetic nanoscale glycomaterials Academic Article
- Improved syntheses of phosphine ligands by direct coupling of diarylbromophosphine with organometallic reagents Academic Article
- Improving the pharmacokinetic and CYP inhibition profiles of azaxanthene-based glucocorticoid receptor modulators-identification of (S)-5-(2-(9-fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanamido)-N-(tetrahydro-2H-pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341) Academic Article
- Ligand-enabled β-C-H arylation of α-amino acids using a simple and practical auxiliary Academic Article
- Natural product synthesis at the interface of chemistry and biology Academic Article
- Nineteen-step total synthesis of (+)-phorbol Academic Article
- Novel analogues of (R)-5-(methylamino)-5,6-dihydro-4H-imidazo 4,5,1-ij quinolin-2(1H)-one (sumanirole) provide clues to dopamine D-2/D-3 receptor agonist selectivity Academic Article
- Organic chemistry: A cure for catalyst poisoning Academic Article
- Palladium-catalyzed dearomative syn-1,4-carboamination Academic Article
- Palladium-catalyzed dearomative syn-1,4-carboamination Academic Article
- Pd(ii)-catalyzed para-selective c-h arylation of monosubstituted arenes Academic Article
- Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif Academic Article
- Regioselective base-free intermolecular aminohydroxylations of hindered and functionalized alkenes Academic Article
- Scalable and sustainable electrochemical allylic C-H oxidation Academic Article
- Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B Academic Article
- Sequential one-pot enzymatic synthesis of oligo-N-acetyllactosamine and its multi-sialylated extensions Academic Article
- Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands Academic Article
- Site-specific immobilization of enzymes on magnetic nanoparticles and their use in organic synthesis Academic Article
- Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines Academic Article
- Strain-release amination Academic Article
- Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry Academic Article
- Sustainable practices in medicinal chemistry Part 2: Green by design Academic Article
- Switchable catalysis with a light-responsive cavitand Academic Article
- Synthesis and biological evaluation of QRSTUVWXYZA' domains of maitotoxin Academic Article
- Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents Academic Article
- Synthesis and biological evaluation of manassantin analogues for hypoxia-inducible factor 1α inhibition Academic Article
- Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors Academic Article
- Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides Academic Article
- Synthesis of (+)-pancratistatins via catalytic desymmetrization of benzene Academic Article
- Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization Academic Article
- Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization Academic Article
- Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery Academic Article
- Synthesis of oligomeric mannosides and their structure-binding relationship with concanavalin A Academic Article
- Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain Academic Article
- Synthesis: A constructive debate Academic Article
- The synthesis and in vivo evaluation of F-18 PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH) Academic Article
- Total syntheses and initial evaluation of [?[C(-S)NH]Tpg(4)]vancomycin, [?[C(-NH)NH]Tpg(4)]vancomycin, [?[CH2NH]Tpg(4)]vancomycin, and their (4-Chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics Academic Article
- Total syntheses of anominine and tubingensin a Academic Article
- Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens Academic Article
- Total synthesis of hyperforin Academic Article