subject area of
- Advances in understanding the complex mechanisms of DNA interstrand cross-link repair Academic Article
- Cohesin protects genes against γH2AX Induced by DNA double-strand breaks Academic Article
- Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures Academic Article
- CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity Academic Article
- CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks Academic Article
- EEPD1 rescues stressed replication forks and maintains genome stability by promoting end resection and homologous recombination repair Academic Article
- Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication Academic Article
- In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma Academic Article
- Microhomology-mediated end joining and homologous recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells Academic Article
- Niraparib: A poly(ADP-ribose) polymerase (PARP) inhibitor for the treatment of tumors with defective homologous recombination Academic Article
- Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks Academic Article
- The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination Academic Article
- The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects Academic Article
- The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair Academic Article
- Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus Academic Article
- Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks Academic Article