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Homologous Recombination

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  • Advances in understanding the complex mechanisms of DNA interstrand cross-link repair  Academic Article
  • Cohesin protects genes against γH2AX Induced by DNA double-strand breaks  Academic Article
  • Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures  Academic Article
  • CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity  Academic Article
  • CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks  Academic Article
  • EEPD1 rescues stressed replication forks and maintains genome stability by promoting end resection and homologous recombination repair  Academic Article
  • Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication  Academic Article
  • In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma  Academic Article
  • Microhomology-mediated end joining and homologous recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells  Academic Article
  • Niraparib: A poly(ADP-ribose) polymerase (PARP) inhibitor for the treatment of tumors with defective homologous recombination  Academic Article
  • Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks  Academic Article
  • The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination  Academic Article
  • The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects  Academic Article
  • The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair  Academic Article
  • Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus  Academic Article
  • Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks  Academic Article

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