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Th17 Cells

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  • ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells  Academic Article
  • Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells  Academic Article
  • Discovery of 3-cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo 2,3-b pyridin-5-yObenzamide: a potent, selective, and orally bioavailable retinoic acid receptor related orphan receptor C2 inverse agonist  Academic Article
  • Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition  Academic Article
  • Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interference  Academic Article
  • Drug-resistant Th17 cells: culprits in steroid-refractory Crohn's disease?  Academic Article
  • Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase  Academic Article
  • Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation  Academic Article
  • High-affinity IgA needs T(H)17 cell functional plasticity  Academic Article
  • Identification of SR2211: a potent synthetic ROR gamma-selective modulator  Academic Article
  • Identity crisis of Th17 cells: many forms, many functions, many questions  Academic Article
  • In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists  Academic Article
  • Inhibiting oxidative phosphorylation in vivo restrains Th17 effector responses and ameliorates murine colitis  Academic Article
  • LXR-mediated inhibition of CD4(+) T helper cells  Academic Article
  • Metabolic control of T(H)17 and induced T-reg cell balance by an epigenetic mechanism  Academic Article
  • Metabolism of murine T(H)17 cells: Impact on cell fate and function  Academic Article
  • Necessity of lysophosphatidic acid receptor 1 for development of arthritis  Academic Article
  • Pharmacologic repression of retinoic acid receptor-related orphan nuclear receptor gamma is therapeutic in the collagen-induced arthritis experimental model  Academic Article
  • ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes  Academic Article
  • RORs in autoimmune disease  Academic Article
  • SIRT1 deacetylates RORγt and enhances Th17 cell generation  Academic Article
  • Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors  Academic Article
  • Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand  Academic Article
  • T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia  Academic Article
  • Targeting Th17 cells in autoimmune diseases  Academic Article
  • The gut microbiota regulates intestinal CD4 T cells expressing RORγt and controls metabolic disease  Academic Article
  • Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORγt protein  Academic Article

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