subject area of

• A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response  Academic Article
• A blueprint for HIV vaccine discovery  Academic Article
• A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus  Academic Article
• A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses  Academic Article
• A common solution to group 2 influenza virus neutralization  Academic Article
• A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition  Academic Article
• A highly conserved neutralizing epitope on group 2 influenza a viruses  Academic Article
• A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1  Academic Article
• A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus  Academic Article
• A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status  Academic Article
• A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals  Academic Article
• A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies  Academic Article
• A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C  Academic Article
• A panel of igg1 b12 variants with selectively diminished or enhanced affinity for fc gamma receptors to define the role of effector functions in protection against hiv  Academic Article
• A perspective on the structural and functional constraints for immune evasion: insights from influenza virus  Academic Article
• A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield  Academic Article
• A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin  Academic Article
• A shared structural solution for neutralizing ebolaviruses  Academic Article
• A short segment of the hiv-1 gp120 v1/v2 region is a major determinant of resistance to v1/v2 neutralizing antibodies  Academic Article
• A single human papillomavirus vaccine dose improves B cell memory in previously infected subjects  Academic Article
• A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen  Academic Article
• A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates  Academic Article
• A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin  Academic Article
• A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin  Academic Article
• AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges  Academic Article
• Advances in structure-based vaccine design  Academic Article
• Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans  Academic Article
• An engineered mutant of hiv-1 gp120 formulated with adjuvant quil a promotes elicitation of antibody responses overlapping the cd4-binding site  Academic Article
• Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors  Academic Article
• Anti-HIV B Cell lines as candidate vaccine biosensors  Academic Article
• Antibodies that cross-neutralize the tier-2 pseudoviruses are produced in antiretroviral-naive HIV-1-infected children from northern India  Academic Article
• Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike  Academic Article
• Antibody 2g12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the hiv-1 glycan shield if domain exchanged  Academic Article
• Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike  Academic Article
• Antibody SPC-54 provides acute in vivo blockage of the murine protein C system  Academic Article
• Antibody conjugation approach enhances breadth and potency of neutralization of anti-HIV-1 antibodies and CD4-IgG  Academic Article
• Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env  Academic Article
• Antibody responses to envelope glycoproteins in HIV-1 infection  Academic Article
• Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization  Academic Article
• Antibody-mediated neutralization of ebola virus can occur by two distinct mechanisms  Academic Article
• Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding  Academic Article
• Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions  Academic Article
• Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9  Academic Article
• B cell liaison confounds HIV-1 evolution  Academic Article
• B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates  Academic Article
• Biochemically defined hiv-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the cd4-binding site  Academic Article
• Blys-mediated modulation of naive b cell subsets impacts hiv env-induced antibody responses  Academic Article
• Bone marrow plasma cells are a primary source of serum HIV-1-specific antibodies in chronically infected individuals  Academic Article
• Breadth of human immunodeficiency virus-specific neutralizing activity in sera: Clustering analysis and association with clinical variables  Academic Article
• Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a  Academic Article
• Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface  Academic Article
• Broad and potent neutralization of hiv-1 by a gp41-specific human antibody  Academic Article
• Broad neutralization coverage of HIV by multiple highly potent antibodies  Academic Article
• Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers  Academic Article
• Broadly neutralizing antibodies abrogate established hepatitis C virus infection  Academic Article
• Broadly neutralizing antibodies against influenza virus and prospects for universal therapies  Academic Article
• Broadly neutralizing antibodies against influenza viruses  Academic Article
• Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses  Academic Article
• Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans  Academic Article
• Broadly neutralizing antibody responses in a large longitudinal Sub-Saharan HIV primary infection cohort  Academic Article
• Broadly neutralizing monoclonal antibodies 2f5 and 4e10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus shivba-l  Academic Article
• Capitalizing on knowledge of hepatitis C virus neutralizing epitopes for rational vaccine design  Academic Article
• Challenges for structure-based HIV vaccine design  Academic Article
• Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin  Academic Article
• Characterization of virus-like particles in GARDASIL by cryo transmission electron microscopy  Academic Article
• Chemical cross-linking stabilizes native-like HIV-1 envelope glycoprotein trimer antigens  Academic Article
• Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus  Academic Article
• Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer  Academic Article
• Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer  Academic Article
• Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold  Academic Article
• Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5  Academic Article
• Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data  Academic Article
• Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions  Academic Article
• Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies  Academic Article
• Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity  Academic Article
• Cooperativity enables non-neutralizing antibodies to neutralize Ebolavirus  Academic Article
• Cross-neutralization of influenza a viruses mediated by a single antibody loop  Academic Article
• Cross-reactive and potent neutralizing antibody responses in human survivors of natural Ebolavirus infection  Academic Article
• Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer  Academic Article
• Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer  Academic Article
• Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1  Academic Article
• Crystal structure of a soluble cleaved HIV-1 envelope trimer  Academic Article
• Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1  Academic Article
• Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose  Academic Article
• Crystallographic identification of lipid as an integral component of the epitope of HIV broadly neutralizing antibody 4E10  Academic Article
• De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts  Academic Article
• Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection  Academic Article
• Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies  Academic Article
• Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits  Academic Article
• Direct antibody access to the HIV-1 membrane-proximal external region positively correlates with neutralization sensitivity  Academic Article
• Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity  Academic Article
• Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization  Academic Article
• Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies  Academic Article
• Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion  Academic Article
• Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen  Academic Article
• Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies  Academic Article
• Enhanced recognition and neutralization of HIV-1 by antibody-derived CCR5-mimetic peptide variants  Academic Article
• Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein  Academic Article
• Fab mabs specific to ha of influenza virus with h5n1 neutralizing activity selected from immunized chicken phage library  Academic Article
• Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing  Academic Article
• Functional optimization of broadly neutralizing HIV-1 antibody 10E8 by promotion of membrane interactions  Academic Article
• Functional stability of HIV-1 envelope trimer affects accessibility to broadly neutralizing antibodies at its apex  Academic Article
• Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody  Academic Article
• Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies  Academic Article
• Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development  Academic Article
• Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation  Academic Article
• H7N9 influenza virus neutralizing antibodies that possess few somatic mutations  Academic Article
• HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage  Academic Article
• HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogene  Academic Article
• HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile  Academic Article
• HIV-1 neutralizing antibodies induced by native-like envelope trimers  Academic Article
• HIV-1 neutralizing antibodies induced by native-like envelope trimers  Academic Article
• HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization  Academic Article
• Hepatitis C virus E2 envelope glycoprotein core structure  Academic Article
• Heterologous epitope-scaffold prime:Boosting immuno-focuses b cell responses to the hiv-1 gp41 2f5 neutralization determinant  Academic Article
• Heterosubtypic antibodies to influenza A virus have limited activity against cell-bound virus but are not impaired by strain-specific serum antibodies  Academic Article
• Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity  Academic Article
• High-resolution definition of vaccine-elicited b cell responses against the hiv primary receptor binding site  Academic Article
• High-throughput protein engineering improves the antigenicity and stability of soluble HIV-1 envelope glycoprotein SOSIP trimers  Academic Article
• High-throughput screening technologies for botulinum neurotoxins  Academic Article
• Highly conserved protective epitopes on influenza B viruses  Academic Article
• Highly efficient neutralization by plasma antibodies from human immunodeficiency virus type-1 infected individuals on antiretroviral drug therapy  Academic Article
• Highly potent hiv-specific antibody neutralization in vitro translates into effective protection against mucosal shiv challenge in vivo  Academic Article
• Hiv type 1 env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies  Academic Article
• Hiv-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins  Academic Article
• Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses  Academic Article
• Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus  Academic Article
• Human circulating PD-(+)1CXCR3(-)CXCR5(+) memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses  Academic Article
• Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies  Academic Article
• IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform  Academic Article
• IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R  Academic Article
• Identification and characterization of a naturally occurring, efficiently cleaved, membrane-bound, clade A HIV-1 Env, suitable for immunogen design, with properties comparable to membrane-bound BG505  Academic Article
• Identification of CD4-binding site dependent plasma neutralizing antibodies in an HIV-1 Infected Indian individual  Academic Article
• Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes  Academic Article
• Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design  Academic Article
• Immune Focusing and Enhanced Neutralization Induced by HIV-1 gp140 Chemical Cross-Linking  Academic Article
• Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10  Academic Article
• Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice  Academic Article
• Immunization with wild-type or cd4-binding-defective hiv-1 env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus  Academic Article
• Immunogenic display of purified chemically cross-linked HIV-1 spikes  Academic Article
• Immunogenicity evaluation strategy for a second-generation therapeutic, PEG-IFN-β-1a  Academic Article
• Immunogenicity of HIV-1 envelope glycoprotein oligomers  Academic Article
• Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes  Academic Article
• Incomplete neutralization and deviation from sigmoidal neutralization curves for HIV broadly neutralizing monoclonal antibodies  Academic Article
• Influence of novel cd4 binding-defective hiv-1 envelope glycoprotein immunogens on neutralizing antibody and t-cell responses in nonhuman primates  Academic Article
• Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein  Academic Article
• Insights into the trimeric HIV-1 envelope glycoprotein structure  Academic Article
• Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak  Academic Article
• Key gp120 glycans pose roadblocks to the rapid development of VRC01-class antibodies in an HIV-1-infected Chinese donor  Academic Article
• LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth  Academic Article
• Ligand accessibility to the HIV-1 Env co-receptor binding site can occur prior to CD4 engagement and is independent of viral tier category  Academic Article
• Limited or no protection by weakly or nonneutralizing antibodies against vaginal shiv challenge of macaques compared with a strongly neutralizing antibody  Academic Article
• Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry  Academic Article
• Mamu-B*17(+) rhesus macaques vaccinated with env, vif, and nef manifest early control of SIVmac239 replication  Academic Article
• Manipulating the selection forces during affinity maturation to generate cross-reactive hiv antibodies  Academic Article
• Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody  Academic Article
• Mechanism of human antibody-mediated neutralization of Marburg virus  Academic Article
• Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01  Academic Article
• Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies  Academic Article
• Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains  Academic Article
• Model building and refinement of a natively glycosylated HIV-1 Env protein by high-resolution cryoelectron microscopy  Academic Article
• Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies  Academic Article
• Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies  Academic Article
• Murine anti-vaccinia virus D8 antibodies target different epitopes and differ in their ability to block D8 binding to CS-E  Academic Article
• Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity  Academic Article
• N332-directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function  Academic Article
• Neutralization of tier-2 viruses and epitope profiling of plasma antibodies from human immunodeficiency virus type 1 infected donors from India  Academic Article
• Neutralization potential of the plasma of HIV-1 infected Indian patients in the context of Anti-V3 antibody content and antiretroviral theraphy  Academic Article
• Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas  Academic Article
• Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies  Academic Article
• Neutralization takes precedence over IgG or IgA isotype-related functions in mucosal HIV-1 antibody-mediated protection  Academic Article
• Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission  Academic Article
• Neutralizing ebolavirus: Structural insights into the envelope glycoprotein and antibodies targeted against it  Academic Article
• Neutralizing epitopes in the membrane-proximal external region of hiv-1 gp41 are influenced by the transmembrane domain and the plasma membrane  Academic Article
• Optimal combinations of broadly neutralizing antibodies for prevention and treatment of HIV-1 clade C  Academic Article
• Outer domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04  Academic Article
• PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4  Academic Article
• Pan-ebolavirus and pan-filovirus mouse monoclonal antibodies: protection against Ebola and Sudan viruses  Academic Article
• Passive neutralizing antibody controls shiv viremia and enhances b cell responses in infant macaques  Academic Article
• Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques  Academic Article
• Pharmacokinetics and pharmacodynamics of peginterferon beta-1a in patients with relapsing-remitting multiple sclerosis in the randomized ADVANCE study  Academic Article
• Platelet protein S directly inhibits procoagulant activity on platelets and microparticles  Academic Article
• Potent antibody protection against an emerging alphavirus threat  Academic Article
• Potent plasmablast-derived antibodies elicited by the national institutes of health dengue vaccine  Academic Article
• Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity  Academic Article
• Prevalence and predictors for homo- and heterosubtypic antibodies against influenza A virus.  Academic Article
• Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation  Academic Article
• Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate  Academic Article
• Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice  Academic Article
• Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen  Academic Article
• Production and characterization of human anti-V3 monoclonal antibodies from the cells of HIV-1 infected Indian donors  Academic Article
• Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor alpha 1  Academic Article
• Profiling human antibody responses by integrated single-cell analysis  Academic Article
• Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV  Academic Article
• Proof of principle for epitope-focused vaccine design  Academic Article
• Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy  Academic Article
• Protection against high-dose highly pathogenic mucosal siv challenge at very low serum neutralizing titers of the antibody-like molecule cd4-igg2  Academic Article
• Protective efficacy of broadly neutralizing antibodies with incomplete neutralization activity against simian-human immunodeficiency virus in rhesus monkeys  Academic Article
• Purification, modeling, and analysis of botulinum neurotoxin subtype a5 (bont/a5) from clostridium botulinum strain a661222  Academic Article
• Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque  Academic Article
• Rational HIV immunogen design to target specific germline B cell receptors  Academic Article
• Rational antibody-based HIV-1 vaccine design: current approaches and future directions  Academic Article
• Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to hiv-1  Academic Article
• Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus  Academic Article
• Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs.  Academic Article
• Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex  Academic Article
• Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers  Academic Article
• Relationship between antibody 2f5 neutralization of hiv-1 and hydrophobicity of its heavy chain third complementarity-determining region  Academic Article
• Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency  Academic Article
• Rhesus macaque B-cell responses to an HIV-1 trimer vaccine revealed by unbiased longitudinal repertoire analysis  Academic Article
• Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates  Academic Article
• Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins  Academic Article
• Selection pressure on hiv-1 envelope by broadly neutralizing antibodies to the conserved cd4-binding site  Academic Article
• Sequence and structural convergence of broad and potent hiv antibodies that mimic cd4 binding  Academic Article
• Simplifying the synthesis of SIgA: combination of dIgA and rhSC using affinity chromatography  Academic Article
• SnapShot: broadly neutralizing antibodies  Academic Article
• Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice  Academic Article
• Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies  Academic Article
• Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies  Academic Article
• Strategies to determine assay format for the assessment of neutralizing antibody responses to biotherapeutics  Academic Article
• Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins  Academic Article
• Structural basis for Marburg virus neutralization by a cross-reactive human antibody  Academic Article
• Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01  Academic Article
• Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16  Academic Article
• Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12  Academic Article
• Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1  Academic Article
• Structural basis of immune evasion at the site of cd4 attachment on hiv-1 gp120  Academic Article
• Structural basis of preexisting immunity to the 2009 h1n1 pandemic influenza virus  Academic Article
• Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers  Academic Article
• Structural constraints determine the glycosylation of HIV-1 envelope trimers  Academic Article
• Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers  Academic Article
• Structural evolution of glycan recognition by a family of potent HIV antibodies  Academic Article
• Structural insights into key sites of vulnerability on hiv-1 env and influenza ha  Academic Article
• Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors  Academic Article
• Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1  Academic Article
• Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence  Academic Article
• Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy  Academic Article
• Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9  Academic Article
• Structure of a classical broadly neutralizing stem antibody in complex with a pandemic H2 hemagglutinin  Academic Article
• Structure of a classical broadly neutralizing stem antibody in complex with a pandemic h2 hemagglutinin  Academic Article
• Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526  Academic Article
• Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33  Academic Article
• Structure of the apo anti-influenza CH65 Fab  Academic Article
• Structure-based vaccine design in hiv: Blind men and the elephant?  Academic Article
• Structure-guided alterations of the gp41-directed hiv-1 broadly neutralizing antibody 2f5 reveal new properties regarding its neutralizing function  Academic Article
• Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120  Academic Article
• Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies  Academic Article
• Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments  Academic Article
• Targeted isolation of antibodies directed against major sites of SIV Env vulnerability  Academic Article
• Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules  Academic Article
• Targeting the HIV-1 spike and coreceptor with bi- and trispecific antibodies for single-component broad inhibition of entry  Academic Article
• The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies  Academic Article
• The first human epitope map of the alphaviral E1 and E2 proteins reveals a new E2 epitope with significant virus neutralizing activity  Academic Article
• The impact of vaccination on the breadth and magnitude of the antibody response to influenza A viruses in HIV-infected individuals  Academic Article
• Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys  Academic Article
• Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding  Academic Article
• Transplanting supersites of HIV-1 vulnerability  Academic Article
• Trimerization of the HIV transmembrane domain in lipid bilayers modulates broadly neutralizing antibody binding  Academic Article
• Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope  Academic Article
• Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein  Academic Article
• Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin  Academic Article
• Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine  Academic Article
• Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies  Academic Article
• V1/V2 neutralizing epitope is conserved in divergent non-M groups of HIV-1  Academic Article
• Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes  Academic Article
• Vaccine elicitation of high mannose-dependent neutralizing antibodies against the V3-glycan broadly neutralizing epitope in nonhuman primates  Academic Article
• Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign  Academic Article
• Vaccine-elicited tier 2 HIV-1 neutralizing antibodies bind to quaternary epitopes involving glycan-deficient patches proximal to the CD4 binding site  Academic Article
• Variable loop glycan dependency of the broad and potent hiv-1-neutralizing antibodies pg9 and pg16  Academic Article
• Very few substitutions in a germ line antibody are required to initiate significant domain exchange  Academic Article
• Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties  Academic Article
• bNAber: database of broadly neutralizing HIV antibodies  Academic Article
• eCD4-Ig variants that more potently neutralize HIV-1  Academic Article