subject area of

• "Viral deja vu" elicits organ-specific immune disease independent of reactivity to self  Academic Article
• 'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast  Academic Article
• (18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils  Academic Article
• -Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity  Academic Article
• 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation  Academic Article
• 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
• 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females  Academic Article
• 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination  Academic Article
• 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles  Academic Article
• 2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors  Academic Article
• 2-Aminobenzimidazoles as potent Aurora kinase inhibitors  Academic Article
• 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases  Academic Article
• 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of beta-amyloid aggregation  Academic Article
• 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution  Academic Article
• 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 2  Academic Article
• 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth  Academic Article
• 4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase  Academic Article
• 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency  Academic Article
• 5,​6-methanoleukotriene A(4): a potent specific inhibitor for 5-​lipoxygenase  Academic Article
• 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia  Academic Article
• 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission  Academic Article
• 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern  Academic Article
• 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent  Academic Article
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)  Academic Article
• 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2  Academic Article
• 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience  Academic Article
• 8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents  Academic Article
• 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors  Academic Article
• A 1,064 bp fragment from the promoter region of the Col11a2 gene drives LacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos  Academic Article
• A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
• A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus  Academic Article
• A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia  Academic Article
• A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity  Academic Article
• A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines  Academic Article
• A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells  Academic Article
• A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response  Academic Article
• A CreER mouse to study melanin concentrating hormone signaling in the developing brain  Academic Article
• A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth  Academic Article
• A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence  Academic Article
• A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication  Academic Article
• A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the nkg2d receptor  Academic Article
• A FAAH-regulated class of N-acyl taurines that activates TRP ion channels  Academic Article
• A Gja8 (Cx50) point mutation causes an alteration of α3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice  Academic Article
• A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection  Academic Article
• A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids  Academic Article
• A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells  Academic Article
• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis  Academic Article
• A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate  Academic Article
• A Protective Strategy against Hyperinflammatory Responses Requiring the Nontranscriptional Actions of GPS2  Academic Article
• A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum  Academic Article
• A T cell receptor-specific blockade of positive selection  Academic Article
• A THEMIS:SHP1 complex promotes T-cell survival  Academic Article
• A TRP channel that senses cold stimuli and menthol  Academic Article
• A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction  Academic Article
• A binding site for homeodomain and pax proteins is necessary for l1 cell adhesion molecule gene expression by pax-6 and bone morphogenetic proteins  Academic Article
• A binding site for pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord  Academic Article
• A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy  Academic Article
• A brain detoxifying enzyme for organophosphorus nerve poisons  Academic Article
• A candidate circuit approach to investigating autism  Academic Article
• A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation  Academic Article
• A catechol-O-methyltransferase that is essential for auditory function in mice and humans  Academic Article
• A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1)  Academic Article
• A cell-autonomous requirement for the cell cycle regulatory protein, rb, in neuronal migration  Academic Article
• A cellular gene encodes scrapie prp 27-30 protein  Academic Article
• A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis  Academic Article
• A ceramide-1-phosphate analogue, pcera-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages  Academic Article
• A change in the conformation of prions accompanies the emergence of a new prion strain  Academic Article
• A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins  Academic Article
• A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor  Academic Article
• A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor  Academic Article
• A chemically induced vaccine strategy for prostate cancer  Academic Article
• A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase  Academic Article
• A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses  Academic Article
• A chimeric mouse model of Gaucher disease  Academic Article
• A combinatorial system for cloning and expressing the catalytic antibody repertoire in escherichia-coli  Academic Article
• A common and unstable copy number variant is associated with differences in glo1 expression and anxiety-like behavior  Academic Article
• A common antiviral cytotoxic lymphocyte-t epitope for diverse major histocompatibility complex haplotypes - implications for vaccination  Academic Article
• A common solution to group 2 influenza virus neutralization  Academic Article
• A comparative analysis of the immunological evolution of antibody 28B4  Academic Article
• A comparative encyclopedia of DNA elements in the mouse genome  Academic Article
• A comparison of 129S2/SvHsd and C57BL/6JO1aHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically modified mice  Academic Article
• A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis  Academic Article
• A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models  Academic Article
• A comparison of t cell memory against the same antigen induced by virus versus intracellular bacteria  Academic Article
• A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis  Academic Article
• A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol  Academic Article
• A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells  Academic Article
• A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform  Academic Article
• A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses  Academic Article
• A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles  Academic Article
• A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase  Academic Article
• A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions  Academic Article
• A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function  Academic Article
• A cost-effective fluorescence mini-microscope for biomedical applications  Academic Article
• A critical evaluation of a nicotine vaccine within a self-administration behavioral model  Academic Article
• A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection  Academic Article
• A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
• A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling  Academic Article
• A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy  Academic Article
• A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response  Academic Article
• A curly-tail modifier locus, mct1, on mouse chromosome-17  Academic Article
• A customized self-assembling peptide hydrogel for dental pulp tissue engineering  Academic Article
• A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally  Academic Article
• A designer AAV variant permits efficient retrograde access to projection neurons  Academic Article
• A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle  Academic Article
• A direct GABAergic output from the basal ganglia to frontal cortex  Academic Article
• A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification  Academic Article
• A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d  Academic Article
• A distribution-free test for tumor-growth curve analyses with application to an animal tumor-immunotherapy experiment  Academic Article
• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use  Academic Article
• A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes  Academic Article
• A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis  Academic Article
• A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli  Academic Article
• A dual-function DNA vaccine encoding carcinoembryonic antigen and cd40 ligand trimer induces t cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice  Academic Article
• A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis  Academic Article
• A dynamic search process underlies microRNA targeting  Academic Article
• A dystroglycan mutation associated with limb-girdle muscular dystrophy  Academic Article
• A factor IX-deficient mouse model for hemophilia B gene therapy  Academic Article
• A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol)  Academic Article
• A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange  Academic Article
• A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition  Academic Article
• A fluorescent plate reader assay for ceramide kinase  Academic Article
• A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome  Academic Article
• A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity  Academic Article
• A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function  Academic Article
• A fragment of human TrpRS as a potent antagonist of ocular angiogenesis  Academic Article
• A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells  Academic Article
• A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen  Academic Article
• A functional genomics strategy reveals Rora as a component of the mammalian circadian clock  Academic Article
• A functional hot spot for antigen recognition in a superagonist TCR/MHC complex  Academic Article
• A functional interaction between RIP140 and PGC-1 alpha regulates the expression of the lipid droplet protein CIDEA  Academic Article
• A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding  Academic Article
• A gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesity  Academic Article
• A gene atlas of the mouse and human protein-encoding transcriptomes  Academic Article
• A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells  Academic Article
• A genetic analysis of lupus  Academic Article
• A genetic approach to the generation of antibodies with enhanced catalytic activities  Academic Article
• A genetic determinant of the striatal dopamine response to alcohol in men  Academic Article
• A genetic determinant that specifically regulates the frequency of hematopoietic stem cells  Academic Article
• A genetic marker in the variable region of light chains of mouse immunoglobulins  Academic Article
• A genetic-locus regulates the expression of tissue-specific messenger-rnas from multiple transcription units  Academic Article
• A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing  Academic Article
• A genetically humanized mouse model for hepatitis C virus infection  Academic Article
• A genomic screen for activators of the antioxidant response element  Academic Article
• A genomic screen identifies TYRO3 as a MITF regulator in melanoma  Academic Article
• A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse  Academic Article
• A global map of lipid-binding proteins and their ligandability in cells  Academic Article
• A glycoengineered enzyme with multiple mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes  Academic Article
• A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival  Academic Article
• A heat-modifiable outer-membrane protein carries an antigen specific for the species Yersinia-enterocolitica and Yersinia-pseudotuberculosis  Academic Article
• A heat-sensitive TRP channel expressed in keratinocytes  Academic Article
• A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain  Academic Article
• A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis  Academic Article
• A highly conserved neutralizing epitope on group 2 influenza a viruses  Academic Article
• A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia  Academic Article
• A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature  Academic Article
• A hormone-dependent module regulating energy balance  Academic Article
• A human aminoacyl-tRNA synthetase as a regulator of angiogenesis  Academic Article
• A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo  Academic Article
• A human recombinant monoclonal antibody to cocaine: preparation, characterization and behavioral studies  Academic Article
• A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol  Academic Article
• A human-brain glycoprotein related to the mouse-cell adhesion molecule l1  Academic Article
• A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy  Academic Article
• A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus  Academic Article
• A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen  Academic Article
• A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters  Academic Article
• A keratinocyte-responsive gamma delta tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis  Academic Article
• A key role for lipoic acid synthesis during Plasmodium liver stage development  Academic Article
• A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues  Academic Article
• A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna  Academic Article
• A large noncoding rna is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas  Academic Article
• A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells  Academic Article
• A legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis  Academic Article
• A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status  Academic Article
• A leukocyte homologue of the il-8 receptor cxcr-2 mediates the accumulation of macrophages in atherosclerotic lesions of ldl receptor-deficient mice  Academic Article
• A liver-selective LXR inverse agonist that suppresses hepatic steatosis  Academic Article
• A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses  Academic Article
• A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGf/TNF receptor family  Academic Article
• A major conformational change in p97 aaa atpase upon atp binding  Academic Article
• A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells  Academic Article
• A metabolomics strategy for detecting protein-metabolite interactions to identify natural nuclear receptor ligands  Academic Article
• A method for rapid mouse siderocyte enrichment  Academic Article
• A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting  Academic Article
• A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids  Academic Article
• A minimally lipidated form of cell-derived apolipoprotein e exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins  Academic Article
• A minor catalytic activity of src family kinases is sufficient for maximal activation of mast cells via the high-affinity ige receptor  Academic Article
• A mitochondrial targeting two-channel responsive fluorescence probe for imaging the superoxide radical anion in vitro and in vivo  Academic Article
• A model for familial exudative vitreoretinopathy caused by LPR5 mutations  Academic Article
• A model of measles virus-induced immunosuppression: Enhanced susceptibility of neonatal human pbls  Academic Article
• A model of the cell-autonomous mammalian circadian clock  Academic Article
• A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells  Academic Article
• A molecular link between the active component of marijuana and Alzheimer's disease pathology  Academic Article
• A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3  Academic Article
• A molecular switch controls interspecies prion disease transmission in mice  Academic Article
• A monoclonal-antibody directed against the beta-1-adrenergic receptor from turkey erythrocyte-membranes  Academic Article
• A monoclonal-antibody specific for conidia and mycelium wall layer of penicillium and aspergillus  Academic Article
• A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration  Academic Article
• A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons  Academic Article
• A mouse model for nonsyndromic deafness (dfnb12) links hearing loss to defects in tip links of mechanosensory hair cells  Academic Article
• A mouse model of accelerated liver aging caused by a defect in DNA repair  Academic Article
• A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice  Academic Article
• A multifunctional bispecific antibody protects against Pseudomonas aeruginosa  Academic Article
• A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen  Academic Article
• A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans  Academic Article
• A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response  Academic Article
• A murine t-cell receptor gene-complex - isolation, structure and rearrangement  Academic Article
• A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen  Academic Article
• A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα  Academic Article
• A near-IR uncaging strategy based on cyanine photochemistry  Academic Article
• A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain  Academic Article
• A new approach to high-sensitivity differential hybridization  Academic Article
• A new method of embryonic culture for assessing global changes in brain organization  Academic Article
• A new murine CD4+ T cell subset with an unrestricted cytokine profile  Academic Article
• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis  Academic Article
• A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity  Academic Article
• A nonapoptotic role for BAX and BAK in eicosanoid metabolism  Academic Article
• A novel 2 '-(n-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models  Academic Article
• A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma  Academic Article
• A novel ELISA for mouse activated protein C in plasma  Academic Article
• A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target  Academic Article
• A novel Netrin-l-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching  Academic Article
• A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease  Academic Article
• A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells  Academic Article
• A novel and simple method for culturing pericytes from mouse brain  Academic Article
• A novel approach for in vivo measurement of mouse red cell redox status  Academic Article
• A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system  Academic Article
• A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis  Academic Article
• A novel class II MHC molecule with unusual tissue distribution  Academic Article
• A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties  Academic Article
• A novel cross-talk in diacylglycerol signaling the rac-gap beta 2-chimaerin is negatively regulated by protein kinase c delta-mediated phosphorylation  Academic Article
• A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1  Academic Article
• A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects  Academic Article
• A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis  Academic Article
• A novel generation of heparan sulfate mimetics for the treatment of prion diseases  Academic Article
• A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation  Academic Article
• A novel method for generating region-specific monoclonal-antibodies to modified proteins - application to the identification of human glucosylated low-density lipoproteins  Academic Article
• A novel method to establish microglia-free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia  Academic Article
• A novel monoclonal antibody, L1A3, is directed to the functional site of the αv integrin subunit  Academic Article
• A novel neuron-specific DNA end-binding factor in the murine brain  Academic Article
• A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action  Academic Article
• A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease  Academic Article
• A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β  Academic Article
• A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal cns  Academic Article
• A novel synthetic bipartite carrier protein for developing glycotope-based vaccines  Academic Article
• A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system  Academic Article
• A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines  Academic Article
• A novel vascular endothelial growth factor heparin-binding domain substructure binds to glycosaminoglycans in vivo and localizes to tumor microvascular endothelium  Academic Article
• A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests  Academic Article
• A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct  Academic Article
• A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects  Academic Article
• A pRb-responsive, RGD-modified, and Hyaluronidase-armed Canine Oncolytic Adenovirus for Application in Veterinary Oncology  Academic Article
• A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity  Academic Article
• A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration  Academic Article
• A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas  Academic Article
• A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects  Academic Article
• A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice  Academic Article
• A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones  Academic Article
• A peripheral and central t-cell antigen recognized by a monoclonal thymocytotoxic autoantibody from new-zealand black mice  Academic Article
• A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries  Academic Article
• A phase i/ib trial of murine monoclonal anti-gd2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma - a report of the children's cancer group  Academic Article
• A phase-i study of human mouse chimeric antiganglioside gd2 antibody ch14.18 in patients with neuroblastoma  Academic Article
• A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins  Academic Article
• A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia  Academic Article
• A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein  Academic Article
• A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase ii in t cells: From activation to unresponsiveness  Academic Article
• A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer's disease mice  Academic Article
• A platform stratifying a sequestering agent and a pharmacological antagonist as a means to negate botulinum neurotoxicity  Academic Article
• A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice  Academic Article
• A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding  Academic Article
• A population of murine gamma delta T cells that recognize an inducible MHC class Ib molecule  Academic Article
• A porous silicon-based optical interferometric biosensor  Academic Article
• A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic  Academic Article
• A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis  Academic Article
• A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo  Academic Article
• A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake  Academic Article
• A potential suppressive effect of natural antisense IL-1β RNA on lipopolysaccharide-induced IL-1β expression  Academic Article
• A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis  Academic Article
• A proapoptotic peptide for the treatment of solid tumors  Academic Article
• A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale  Academic Article
• A putative bacterial ABC transporter circumvents the essentiality of signal peptidase  Academic Article
• A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes  Academic Article
• A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions  Academic Article
• A rabbit antiserum detects a vh j558 subgroup marker highly expressed among anti-alprenolol antibodies  Academic Article
• A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation  Academic Article
• A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists  Academic Article
• A rationally designed agonist antibody fragment that functionally mimics thrombopoietin  Academic Article
• A receptor-induced by lymphocyte-activation (ILA) - a new member of the human nerve-growth-factor tumor-necrosis-factor receptor family  Academic Article
• A recombinant antibody interleukin-2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice  Academic Article
• A recombinant human enzyme for enhanced interstitial transport of therapeutics  Academic Article
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• A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors  Academic Article
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• A role for dual viral hits in causation of subacute sclerosing panencephalitis  Academic Article
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• A role of apolipoprotein D in triglyceride metabolism  Academic Article
• A role of the fast ATP-gated P2X(1) cation channel in thrombosis of small arteries in vivo  Academic Article
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• A screening-based approach to circumvent tumor microenvironment-driven intrinsic resistance to BCR-ABL+ inhibitors in Ph+ acute lymphoblastic leukemia  Academic Article
• A second fatty acid amide hydrolase with variable distribution among placental mammals  Academic Article
• A second mammalian n-myristoyltransferase  Academic Article
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• A semisynthetic carbohydrate-lipid vaccine that protects against S-pneumoniae in mice  Academic Article
• A shared neural ensemble links distinct contextual memories encoded close in time  Academic Article
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• A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome  Academic Article
• A single amino-acid change in the mouse peroxisome proliferator-activated receptor-alpha alters transcriptional responses to peroxisome proliferators  Academic Article
• A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis  Academic Article
• A single nucleotide difference in the gene for myelin proteolipid protein defines the jimpy mutation in mouse  Academic Article
• A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection  Academic Article
• A single-cell roadmap of lineage bifurcation in human ESC models of embryonic brain development  Academic Article
• A single-stranded nucleic-acid binding sequence common to the heterogeneous nuclear ribonucleoparticle protein-a1 and murine recombinant virus gp70  Academic Article
• A single-subunit nadh-quinone oxidoreductase renders resistance to mammalian nerve cells against complex i inhibition  Academic Article
• A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships  Academic Article
• A small molecule RAS-mimetic disrupts RAS association with effector proteins to block signaling  Academic Article
• A small molecule inhibits deregulated NRF2 transcriptional activity in cancer  Academic Article
• A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth  Academic Article
• A small molecule primes embryonic stem cells for differentiation  Academic Article
• A small molecule promotes mitochondrial fusion in mammalian cells  Academic Article
• A small molecule that directs differentiation of human ESCs into the pancreatic lineage  Academic Article
• A small molecule that mimics the BB-loop in the Toll Interleukin-1 (IL-1) receptor domain of MyD88 attenuates Staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice  Academic Article
• A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells  Academic Article
• A small ubiquitin-related polypeptide involved in targeting rangap1 to nuclear pore complex protein ranbp2  Academic Article
• A small-molecule antagonist of the hedgehog signaling pathway  Academic Article
• A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog  Academic Article
• A smooth muscle-like origin for beige adipocytes  Academic Article
• A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity  Academic Article
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• A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons  Academic Article
• A spontaneous rheumatoid arthritis-like disease in mrl/1 mice  Academic Article
• A spontaneously arising pancreatic tumor does not promote the differentiation of naive CD8+ T lymphocytes into effector CTL  Academic Article
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• A transgenic mouse for in vivo detection of endogenous labeled mRNA  Academic Article
• A transgenic mouse model for measles virus infection of the brain  Academic Article
• A transgenic mouse model of the chronic hepatitis B surface antigen carrier state  Academic Article
• A transgenic mouse model to assess the interaction of cytotoxic t-lymphocytes with virally infected, class-i mhc-expressing astrocytes  Academic Article
• A trojan horse with a sweet tooth  Academic Article
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• A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin  Academic Article
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• AAV8-mediated gene transfer of interleukin-4 to endogenous beta-cells prevents the onset of diabetes in NOD mice  Academic Article
• AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior  Academic Article
• ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC  Academic Article
• ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system  Academic Article
• ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice  Academic Article
• ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells  Academic Article
• ADAP is required for normal alpha IIb beta 3 activation by VWF/GP Ib-IX-V and other agonists  Academic Article
• AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin  Academic Article
• ALG-2 divalent-ion affinity: Calorimetric analysis of the des23 versions reveals high-affinity site for Mg2+  Academic Article
• AMPAR-independent effect of striatal αCaMKII promotes the sensitization of cocaine reward  Academic Article
• AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation  Academic Article
• ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures  Academic Article
• ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1  Academic Article
• ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage  Academic Article
• ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor  Academic Article
• ATP-sensitive potassium channel (K-ATP)-dependent regulation of cardiotropic viral infections  Academic Article
• Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness  Academic Article
• Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6  Academic Article
• Aberrant maturation of the immune-response to the thymus-independent antigen dnp-lys-ficoll by new-zealand black mice  Academic Article
• Aberrant maturational characteristics of immune-responses of nzb mice to autologous and heterologous erythrocyte antigens  Academic Article
• Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality  Academic Article
• Aberrant wound healing and tgf-beta production in the autoimmune-prone mrl/+ mouse  Academic Article
• Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells  Academic Article
• Abl oncogene expression in non-hodgkin lymphomas: Correlation to histological differentiation and clinical status  Academic Article
• Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity  Academic Article
• Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch  Academic Article
• Ablation of beta 1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation  Academic Article
• Ablation of cd22 in ligand-deficient mice restores b cell receptor signaling  Academic Article
• Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice  Academic Article
• Ablation of the prion protein (prp) gene in mice prevents scrapie and facilitates production of anti-prp antibodies  Academic Article
• Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine  Academic Article
• Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss  Academic Article
• Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model  Academic Article
• Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes  Academic Article
• Abrogation of complex glycosylation by swainsonine results in strain- and cell-specific inhibition of prion replication  Academic Article
• Abrogation of murine lupus by the xid gene is associated with reduced responsiveness of b-cells to t-cell-helper signals  Academic Article
• Absence of CTL responses to early viral antigens facilitates viral persistence  Academic Article
• Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice  Academic Article
• Absence of LPA1 signaling results in defective cortical development  Academic Article
• Absence of alpha3 (Cx46) and alpha8 (Cx50) connexins leads to cataracts by affecting lens inner fiber cells  Academic Article
• Absence of an antigen-specific helper T cell required for the expression of the T 15 idiotype in mice treated with anti-mu antibody  Academic Article
• Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport  Academic Article
• Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant  Academic Article
• Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse  Academic Article
• Absence of the alpha v beta 3 integrin dictates the time-course of angiogenesis in the hypoxic central nervous system: Accelerated endothelial proliferation correlates with compensatory increases in alpha 5 beta 1 integrin expression  Academic Article
• Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass  Academic Article
• Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors  Academic Article
• Accelerated aging of intervertebral discs in a mouse model of progeria  Academic Article
• Accelerated, aging-dependent development of osteoarthritis in alpha 1 integrin-deficient mice  Academic Article
• Accumulation of extracellular matrix and developmental dysregulation in the pancreas by transgenic production of transforming growth factor-beta 1  Academic Article
• Acquisition of drug resistance and dependence by prions  Academic Article
• Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: Effects of opioid receptor-like 1 receptor agonists and naloxone  Academic Article
• Action of RORs and their ligands in (patho)physiology  Academic Article
• Action spectrum of ultraviolet light-induced damage to nuclear DNA in vivo  Academic Article
• Actions of a picomolar short-acting S1P(1) agonist in S1P(1)-eGFP knock-in mice  Academic Article
• Activated and memory cd8(+) t cells can be distinguished by their cytokine profiles and phenotypic markers  Academic Article
• Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice  Academic Article
• Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1  Academic Article
• Activated protein C analog protects from ischemic stroke and extends the therapeutic window of tissue-type plasminogen activator in aged female mice and hypertensive rats  Academic Article
• Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage  Academic Article
• Activated protein C preserves functional islet mass after intraportal transplantation - a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death  Academic Article
• Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3  Academic Article
• Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1  Academic Article
• Activated protein C targets CD8(+) dendritic cells to reduce the mortality of endotoxemia in mice  Academic Article
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• Activated protein c blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective  Academic Article
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• Activation kinetics and off-target effects of thymus-initiated cre transgenes  Academic Article
• Activation of B lymphocytes by monovalent anti-Lyb-2 antibodies  Academic Article
• Activation of PPARdelta alters lipid metabolism in db/db mice  Academic Article
• Activation of Rac-1 Rac-2, and Cdc42 by hemopoietic growth factors or cross-linking of the B-lymphocyte receptor for antigen  Academic Article
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• Activation of b lymphocytes by locally concentrated concanavalin a  Academic Article
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• Activation of endothelial cell protease activated receptor 1 by the protein c pathway  Academic Article
• Activation of human effector cells by a tumor reactive recombinant anti-ganglioside gd(2) interleukin-2 fusion protein (ch14.18-il2)  Academic Article
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• Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity  Academic Article
• Activation of lysophosphatidic acid receptor type 1 contributes to pathophysiology of spinal cord injury  Academic Article
• Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death  Academic Article
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• Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset of B lymphocytes  Academic Article
• Activation of multidrug resistance (P-glycoprotein) mdr3/mdr1a gene during the development of hepatocellular carcinoma in hepatitis B virus transgenic mice  Academic Article
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• Activation of neutral sphingomyelinase by IL-1β requires the type 1 interleukin 1 receptor  Academic Article
• Activation of p38α in T cells regulates the intestinal host defense against attaching and effacing bacterial infections  Academic Article
• Activation of preexisting t cell clones by targeted interleukin 2 therapy  Academic Article
• Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells  Academic Article
• Activation of rabbit tlr9 by different cpg-odn optimized for mouse and human tlr9  Academic Article
• Activation of spontaneous murine leukemia virus-related antigen by lymphocytic choriomeningitis virus  Academic Article
• Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer  Academic Article
• Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats  Academic Article
• Activation of the alternative complement pathway by fetal calf serum and mouse thymocytes  Academic Article
• Activation of the cytotactin promoter by the homeobox-containing gene evx-1  Academic Article
• Activation of the endocannabinoid system by organophosphorus nerve agents  Academic Article
• Activation of the first component of human-complement, c1, by monoclonal-antibodies directed against different domains of subcomponent c1q  Academic Article
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• Activation rather than Foxp3 expression determines that TGF-β-induced regulatory T cells out-compete naïve T cells in dendritic cell clustering  Academic Article
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• Active immunization with a glycolipid transition state analogue protects against endotoxic shock  Academic Article
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• Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health  Academic Article
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• Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling  Academic Article
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• Adoptive transfer of neonatal T lymphocytes rescues immunoglobulin production in mice with severe combined immune deficiency  Academic Article
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• Adult mice generated from induced pluripotent stem cells  Academic Article
• Adult mouse brain gene expression patterns bear an embryologic imprint  Academic Article
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• Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo  Academic Article
• Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity  Academic Article
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• Allelic exclusion of the tcr alpha-chain is an active process requiring tcr-mediated signaling and c-cbl  Academic Article
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• Analysis of lymphocytic choriomeningitis virus gene expression in acutely and persistently infected mice  Academic Article
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• Antifungal imidazoles block assembly of inducible no synthase into an active dimer  Academic Article
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• Antigen-driven B cell differentiation in vivo  Academic Article
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• Antigens associated with human squamous-cell lung-carcinoma defined by murine monoclonal-antibodies  Academic Article
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• Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies  Academic Article
• Anxiolytic effects of Julibroside C-1 isolated from Albizzia julibrissin in mice  Academic Article
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• Apoa1 reduces free cholesterol accumulation in atherosclerotic lesions of apoe-deficient mice transplanted with apoe-expressing macrophages  Academic Article
• Apolipoprotein a1 increases mitochondrial biogenesis through AMP-activated protein kinase  Academic Article
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• Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus  Academic Article
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• Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors  Academic Article
• Application of high-density array-based signature-tagged mutagenesis to discover novel yersinia virulence-associated genes  Academic Article
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• Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology  Academic Article
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• Approaches to assess functional selectivity in GPCRs: evaluating G protein signaling in an endogenous environment  Academic Article
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• Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors  Academic Article
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• Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice  Academic Article
• Autoimmune diabetes can be induced in transgenic major histocompatibility complex class-ii-deficient mice  Academic Article
• Autoimmune-disease and T-cell immunological recognition  Academic Article
• Autoimmunity and viruses--fact or fiction: Persistent lcm viral infection, anti-lcm viral immune response, and tissue injury  Academic Article
• Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells  Academic Article
• Autologous immune-responses to major oncornavirus polypeptides in unmanipulated akr-j mice  Academic Article
• Autologous regulation of naive t cell homeostasis within the t cell compartment  Academic Article
• Automated reconstruction of three-dimensional neuronal morphology from laser scanning microscopy images  Academic Article
• Automatic annotation of matrix-assisted laser desorption/ionization n-glycan spectra  Academic Article
• Autonomic function in hypertension role of genetic variation at the catecholamine storage vesicle protein chromogranin b  Academic Article
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• Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis  Academic Article
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• Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain  Academic Article
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• B cells as effectors  Academic Article
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• B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates  Academic Article
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• B-cell-tropic interleukins in murine systemic lupus-erythematosus (sle)-1  Academic Article
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• Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice  Academic Article
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• CD4-CD8- thymocytes that express the T-cell receptor may have previously expressed CD8  Academic Article
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• Cellular and molecular mechanisms of memory: The ltp connection  Academic Article
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• Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5  Academic Article
• Cellular prion protein conformation and function  Academic Article
• Cellular requirements for antigen presentation in the induction of a thymus-independent antibody response in vitro  Academic Article
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• Cellular signaling by an agonist-activated receptor g(s)alpha fusion protein  Academic Article
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• Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes  Academic Article
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• Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas  Academic Article
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• Characterization of H7N9 influenza A viruses isolated from humans  Academic Article
• Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis  Academic Article
• Characterization of TCR gene rearrangements during adult murine T cell development  Academic Article
• Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.  Academic Article
• Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo  Academic Article
• Characterization of a membrane-surface glycoprotein associated with t-cell activation  Academic Article
• Characterization of a neuronal interleukin-1 receptor and the corresponding mRNA in the mouse anterior pituitary cell line AtT-20  Academic Article
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• Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential  Academic Article
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• Characterization of antibody responses to purified hiv-1 gp120 glycoproteins fused with the molecular adjuvant c3d  Academic Article
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• Characterization of highper, an enu-induced mouse mutant with abnormal psychostimulant and stress responses  Academic Article
• Characterization of ia antigens in mouse serum  Academic Article
• Characterization of immature CD4+CD8-CD3- thymocytes  Academic Article
• Characterization of lpa(2) (edg4) and lpa(1)/lpa(2) (edg2/edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)  Academic Article
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• Characterization of murine cytolytic-helper hybrid t-cell clones  Academic Article
• Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo  Academic Article
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• Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro  Academic Article
• Characterization of splenic lymphoid cells in fetal and newborn mice  Academic Article
• Characterization of stem cell-like cancer cells in immune-competent mice  Academic Article
• Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands  Academic Article
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• Characterization of the inflammatory response during acute measles encephalitis in nse-cd46 transgenic mice  Academic Article
• Characterization of the murine antigenic determinant, designated l3t4a, recognized by monoclonal-antibody gk1.5 - expression of l3t4a by functional t-cell clones appears to correlate primarily with class ii mhc antigen-reactivity  Academic Article
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• Characterization of the transformation-specific sequences of avian erythroblastosis virus in normal vertebrate cells  Academic Article
• Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases  Academic Article
• Characterization of two monoclonal antibodies against human tissue-type plasminogen activator  Academic Article
• Characterization of vascular adhesion molecules that may facilitate progenitor homing in the post-natal mouse thymus  Academic Article
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• Characterization, serological specificity, and diagnostic possibilities of monoclonal-antibodies against legionella-pneumophila  Academic Article
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• Chemical dissection of mammalian spermatozoa  Academic Article
• Chemical generation of bispecific antibodies  Academic Article
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• Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice  Academic Article
• Cocaine analog coupled to disrupted adenovirus: A vaccine strategy to evoke high-titer immunity against addictive drugs  Academic Article
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• Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors  Academic Article
• Coxsackievirus b3 and the neonatal cns - the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease  Academic Article
• Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway  Academic Article
• Coxsackievirus b3-induced myocarditis - perforin exacerbates disease, but plays no detectable role in virus clearance  Academic Article
• Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo  Academic Article
• Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo  Academic Article
• Coxsackievirus infection of the pancreas: Evaluation of receptor expression, pathogenesis, and immunopathology  Academic Article
• Coxsackievirus preferentially replicates and induces cytopathic effects in undifferentiated neural progenitor cells  Academic Article
• Coxsackievirus replication and the cell cycle: A potential regulatory mechanism for viral persistence/latency  Academic Article
• Coxsackievirus targets proliferating neuronal progenitor cells in the neonatal CNS  Academic Article
• Cre recombinase-mediated gene deletion in layer 4 of murine sensory cortical areas  Academic Article
• Creb coactivators direct anabolic responses and enhance performance of skeletal muscle  Academic Article
• Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity  Academic Article
• Critical evaluation of bispecific antibodies as targetins agents for boron neutron capture therapy of brain tumors  Academic Article
• Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus  Academic Article
• Critical role for glucocorticoid receptors in stress-induced and ethanol-induced locomotor sensitization  Academic Article
• Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses  Academic Article
• Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response  Academic Article
• Critical role of transmethylation in TLR signaling and systemic lupus erythematosus  Academic Article
• Cross-linking cellular prion protein triggers neuronal apoptosis in vivo  Academic Article
• Cross-linking of lipopolysaccharide (lps) to cd14 on thp-1 cells mediated by lps-binding protein  Academic Article
• Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein  Academic Article
• Cross-neutralization of influenza a viruses mediated by a single antibody loop  Academic Article
• Cross-reactive and potent neutralizing antibody responses in human survivors of natural Ebolavirus infection  Academic Article
• Cross-reactivity between hl-a and h-2 antigens. Ii. Allogeneic sensitization by xenogeneic soluble lymphocyte antigens (hl-a)  Academic Article
• Crosses of nod mice with the related non strain - a polygenic model for iddm  Academic Article
• Cryo-em visualization of an exposed rgd epitope on adenovirus that escapes antibody neutralization  Academic Article
• Cryopreservation by slow cooling with dmso diminished production of oct-4 pluripotency marker in human embryonic stem cells  Academic Article
• Cryopreservation of cancer-initiating cells derived from glioblastoma  Academic Article
• Cryopreservation of neurospheres derived from human glioblastoma multiforme  Academic Article
• Cryptic epitopes in n-terminally truncated prion protein are exposed in the full-length molecule: Dependence of conformation on ph  Academic Article
• Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis  Academic Article
• Cryptochromes mediate rhythmic repression of the glucocorticoid receptor  Academic Article
• Cryptochromes: bringing the blues to circadian rhythms  Academic Article
• Crystal structure determination of anti-DNA Fab A52  Academic Article
• Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif  Academic Article
• Crystal structure of NMC-4 fab anti-von Willebrand factor A1 domain  Academic Article
• Crystal structure of a cocaine-binding antibody  Academic Article
• Crystal structure of a conserved hypothetical protein (gi : 13879369) from Mouse at 1.90 A resolution reveals a new fold  Academic Article
• Crystal structure of a gamma delta t cell receptor ligand t22: A truncated mhc-like fold  Academic Article
• Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design  Academic Article
• Crystal structure of a putative NADPH-dependent oxidoreductase (GI : 18204011) from mouse at 2.10 Å resolution  Academic Article
• Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 a resolution  Academic Article
• Crystal structure of adenosine 5 '-phosphosulfate kinase from Penicillium chrysogenum  Academic Article
• Crystal structure of an Apo mRNA decapping enzyme (DcpS) from mouse at 1.83 Å resolution  Academic Article
• Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor  Academic Article
• Crystal structure of an mhc class i presented glycopeptide that generates carbohydrate-specific ctl  Academic Article
• Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove  Academic Article
• Crystal structure of mouse cd1d bound to the self ligand phosphatidylcholine: A molecular basis for nkt cell activation  Academic Article
• Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (trem-1) at 1.76 Å  Academic Article
• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser  Academic Article
• Crystal structure of the C-terminal domain of mouse TLR9  Academic Article
• Crystal structure of the TCR co-receptor CD8 alpha alpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution  Academic Article
• Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide  Academic Article
• Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran  Academic Article
• Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding  Academic Article
• Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A  Academic Article
• Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of camp-dependent protein kinase  Academic Article
• Crystal structures of mouse CD1d-iGb3 complex and its cognate v alpha 14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids  Academic Article
• Crystal structures of two I-A(d)-peptide complexes reveal that high affinity can be achieved without large anchor residues  Academic Article
• Crystal-structure of a human-immunodeficiency-virus type-1 neutralizing antibody, 50.1, in complex with its v3 loop peptide antigen  Academic Article
• Crystal-structure of an h-2k(b)-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove  Academic Article
• Crystal-structure of murine cyclophilin-c complexed with immunosuppressive drug cyclosporine-a  Academic Article
• Crystal-structures of 2 viral peptides in complex with murine mhc class-i h-2k(b)  Academic Article
• Crystallin gamma B-I4F mutant protein binds to alpha-crystallin and affects lens transparency  Academic Article
• Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition-state analog  Academic Article
• Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides  Academic Article
• Crystallization, sequence, and preliminary crystallographic data for an antipeptide-fab-50.1 and peptide complexes with the principal neutralizing determinant of hiv-1 gp120  Academic Article
• Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization  Academic Article
• Ctl escape viral variants .1. Generation and molecular characterization  Academic Article
• Cultured astrocytes release a factor that decreases endothelin-1 secretion by brain microvessel endothelial-cells  Academic Article
• Cultures of astrocytes and microglia express interleukin 18  Academic Article
• Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient  Academic Article
• Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function  Academic Article
• Cutting edge: Developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development  Academic Article
• Cutting edge: Early ifn-gamma signaling directly enhances primary antivliwal cd4(+) t cell responses  Academic Article
• Cutting edge: IL-13Rα1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide  Academic Article
• Cutting edge: Impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein  Academic Article
• Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver  Academic Article
• Cutting edge: Lack of high affinity competition for peptide in polyclonal cd4(+) responses unmasks il-4 production  Academic Article
• Cutting edge: Priming of NK cells by IL-18  Academic Article
• Cutting edge: Recent immune status determines the source of antigens that drive homeostatic t cell expansion  Academic Article
• Cutting edge: The tyrosine phosphatase SHP-1 regulates thymocyte positive selection  Academic Article
• Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection  Academic Article
• Cutting edge: Trimolecular interaction of tcr with mhc class ii and bacterial superantigen shows a similar affinity to mhc : Peptide ligands  Academic Article
• Cutting edge: dendritic epidermal gamma delta T cell ligands are rapidly and locally expressed by keratinocytes following cutaneous wounding  Academic Article
• Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect  Academic Article
• Cyclic regulation of sensory perception by a female hormone alters behavior  Academic Article
• Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients  Academic Article
• Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcription  Academic Article
• Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes  Academic Article
• Cyclin e-induced s phase without activation of the prb/e2f pathway  Academic Article
• Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities  Academic Article
• Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins  Academic Article
• Cyclin-dependent kinase-associated proteins cks1 and cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells  Academic Article
• Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity  Academic Article
• Cyclooxygenase-2: Where are we in 2003? Cardiovascular risk and cox-2 inhibitors  Academic Article
• Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex  Academic Article
• Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?  Academic Article
• Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception  Academic Article
• Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A  Academic Article
• Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile  Academic Article
• Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors  Academic Article
• Cytoimmunotherapy for persistent virus-infection reveals a unique clearance pattern from the central-nervous-system  Academic Article
• Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials  Academic Article
• Cytokine gene-therapy with interleukin-2-transduced fibroblasts - effects of il-2 dose on antitumor immunity  Academic Article
• Cytokine regulation of TNF-alpha mRNA and protein production by unprimed macrophages from C57Bl/6 and NZW mice  Academic Article
• Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct jak kinase signaling pathways  Academic Article
• Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells  Academic Article
• Cytokine-mediated survival from lethal herpes-simplex virus-infection - role of programmed neuronal death  Academic Article
• Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures  Academic Article
• Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase c-dependent activation of the alpha 6 beta 1 integrin  Academic Article
• Cytokines suppress apoptosis independent of increases in reactive oxygen levels  Academic Article
• Cytolytic T-lymphocyte response to isolated class I H-2 proteins and influenza peptides  Academic Article
• Cytomegalovirus causes a latent infection in undifferentiated cells and is activated by induction of cell-differentiation  Academic Article
• Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers  Academic Article
• Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes  Academic Article
• Cytoprotective-selective activated protein C attenuates pseudomonas aeruginosa-induced lung injury in mice  Academic Article
• Cytoprotective-selective activated protein C therapy for ischaemic stroke  Academic Article
• Cytoskeletal and morphologic impact of cellular oxidant injury  Academic Article
• Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies  Academic Article
• Cytosolic prion protein in neurons  Academic Article
• Cytotactin and its proteoglycan ligand mark structural and functional boundaries in somatosensory cortex of the early postnatal mouse  Academic Article
• Cytotactin binding - inhibition of stimulated proliferation and intracellular alkalinization in fibroblasts  Academic Article
• Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: interferon gamma, but not tumour necrosis factor alpha, displays antiviral activity in vivo  Academic Article
• Cytotoxic T-lymphocytes cleanse viral gene-products from individually infected neurons and lymphocytes in mice persistently infected with lymphocytic choriomeningitis virus  Academic Article
• Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice  Academic Article
• Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-jun n-terminal kinase  Academic Article
• D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain  Academic Article
• DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses  Academic Article
• DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis  Academic Article
• DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression  Academic Article
• DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization  Academic Article
• DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3  Academic Article
• DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria  Academic Article
• DNA immunization  Academic Article
• DNA immunization can stimulate florid local inflammation, and the antiviral immunity induced varies depending on injection site  Academic Article
• DNA immunization confers protection against lethal lymphocytic choriomeningitis virus-infection  Academic Article
• DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice  Academic Article
• DNA immunization to prevent autoimmune diabetes  Academic Article
• DNA immunization with minigenes: Low frequency of memory cytotoxic t lymphocytes and inefficient antiviral protection are rectified by ubiquitination  Academic Article
• DNA immunization: Effects of vehicle and route of administration on the induction of protective antiviral immunity  Academic Article
• DNA immunization: Ubiquitination of a viral protein enhances cytotoxic t-lymphocyte induction and antiviral protection but abrogates antibody induction  Academic Article
• DNA methylation and chromatin structure regulate T cell perforin gene expression  Academic Article
• DNA vaccination against vegf receptor 2 reduces atherosclerosis in ldl receptor-deficient mice  Academic Article
• DNA vaccination can break immunological tolerance to prp in wild-type mice and attenuates prion disease after intracerebral challenge  Academic Article
• DNA vaccination to treat autoimmune diabetes  Academic Article
• DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes  Academic Article
• DNA vaccines designed to inhibit tumor growth by suppression of angiogenesis  Academic Article
• DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis  Academic Article
• DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: Implications for eqtl mapping studies  Academic Article
• DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
• DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer  Academic Article
• DNA-sequences preceding the rabbit beta-globin gene are required for formation in mouse l cells of beta-globin rna with the correct 5' terminus  Academic Article
• DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis  Academic Article
• DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect  Academic Article
• DST4 - a new, and probably the last, functional DH gene in the BALB/c mouse  Academic Article
• Dab1 is required for synaptic plasticity and associative learning  Academic Article
• Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation  Academic Article
• Darwinian evolution of prions in cell culture  Academic Article
• Data-driven synthesis of proteolysis-resistant peptide hormones  Academic Article
• De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis  Academic Article
• Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function  Academic Article
• Decay-accelerating factor 1 (daf1) deficiency exacerbates xenobiotic-induced autoimmunity  Academic Article
• Deconstructing transcriptional heterogeneity in pluripotent stem cells  Academic Article
• Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo  Academic Article
• Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase  Academic Article
• Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system  Academic Article
• Decreased brain reward function during nicotine withdrawal in c57bl6 mice: Evidence from intracranial self-stimulation (icss) studies  Academic Article
• Decreased immobility in swimming test by homologous interferon-alpha in mice accompanied with increased cerebral tryptophan level and serotonin turnover  Academic Article
• Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy  Academic Article
• Dedifferentiation of lineage-committed cells by a small molecule  Academic Article
• Deep proteome mapping of mouse kidney based on OFFGel prefractionation reveals remarkable protein post- translational modifications  Academic Article
• Deep sequencing of the murine Igh repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies  Academic Article
• Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation  Academic Article
• Deep-brain magnetic stimulation promotes adult hippocampal neurogenesis and alleviates stress-related behaviors in mouse models for neuropsychiatric disorders  Academic Article
• Defective CD8+ T cell peripheral tolerance in nonobese diabetic mice  Academic Article
• Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene  Academic Article
• Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice  Academic Article
• Defective lymphotoxin-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice  Academic Article
• Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function  Academic Article
• Defects in deletional tolerance of CD8+ T cells in autoimmune diabetes  Academic Article
• Defects in skin γδ T cell function contribute to delayed wound repair in rapamycin-treated mice  Academic Article
• Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist  Academic Article
• Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy  Academic Article
• Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances  Academic Article
• Deficiency of DNA repair nuclease ERCC1-XPF promotes prostate cancer progression in a tissue recombination model  Academic Article
• Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis  Academic Article
• Deficiency of lrp8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis  Academic Article
• Deficiency of the cyclin kinase inhibitor P21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoirnmunity  Academic Article
• Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the pkr gene: Role of irf-1 and nf-kappa b  Academic Article
• Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity  Academic Article
• Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase  Academic Article
• Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice  Academic Article
• Defined and scalable differentiation of human oligodendrocyte precursors from pluripotent stem cells in a 3D culture system  Academic Article
• Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns  Academic Article
• Defining parameters for successful immunocytotherapy of persistent viral infection  Academic Article
• Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro  Academic Article
• Defining the conformational features of anchorless, poorly neuroinvasive prions  Academic Article
• Defining the critical hypoxic threshold that promotes vascular remodeling in the brain  Academic Article
• Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome  Academic Article
• Defining the risks of mesenchymal stromal cell therapy  Academic Article
• Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity  Academic Article
• Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis  Academic Article
• Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis  Academic Article
• Delayed and accelerated aging share common longevity assurance mechanisms  Academic Article
• Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors  Academic Article
• Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice  Academic Article
• Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization  Academic Article
• Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival  Academic Article
• Deletion of PREPl causes growth impairment and hypotonia in mice  Academic Article
• Deletion of ghrelin impairs neither growth nor appetite  Academic Article
• Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus  Academic Article
• Deletion of naive CD8 T cells requires persistent antigen and is not programmed by an initial signal from the tolerogenic APC  Academic Article
• Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice  Academic Article
• Deletion of p21 (WAF-1/Cip1) does not induce systemic autoimmunity in female BXSB mice  Academic Article
• Deletion of the nucleotide excision repair gene ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions  Academic Article
• Deletions linked to TP53 loss drive cancer through p53-independent mechanisms  Academic Article
• Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication  Academic Article
• Deliberate removal of T cell help improves virus-neutralizing antibody production  Academic Article
• Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects  Academic Article
• Delineation of a defect in t-cell receptor beta-genes of nzw mice predisposed to autoimmunity  Academic Article
• Delineation of spontaneous erythrocyte autoantibody responses of nzb and other strains of mice  Academic Article
• Delineation of the proinflammatory cytokine cascade in fever induction  Academic Article
• Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes  Academic Article
• Delta(9)-tetrahydrocannabinol immunochemical studies: Haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta(9)-tetrahydrocannabinol  Academic Article
• Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects  Academic Article
• Demonstration of a hematopoietic stem-cell antigen (SC-1) on a murine lymphoma and isolation of variants lacking the antigen  Academic Article
• Demonstration of dehydrogenases and monoamine-oxidase by formation of osmium blacks at sites of hatchetts brown  Academic Article
• Demonstration of developmental anomalies in mouse fetuses by transfer of murine cytomegalovirus DNA-injected eggs to surrogate mothers  Academic Article
• Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation  Academic Article
• Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation  Academic Article
• Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice  Academic Article
• Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity  Academic Article
• Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection  Academic Article
• Dendritic cells produce macrophage inflammatory protein-1 gamma, a new member of the CC chemokine family  Academic Article
• Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice  Academic Article
• Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis  Academic Article
• Dendritic epidermal T cells regulate skin antimicrobial barrier function  Academic Article
• Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1  Academic Article
• Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin  Academic Article
• Dense nuclear cataract caused by the γB-crystallin S11R point mutation  Academic Article
• Density-dependent stimulation and inhibition of cell-growth by agents that disrupt microtubules  Academic Article
• Dentate gyrus volume is reduced before onset of plaque formation in pdapp mice: A magnetic resonance microscopy and stereologic analysis  Academic Article
• Dentin conditioning codetermines cell fate in regenerative endodontics  Academic Article
• Dependence-induced increases in ethanol self-administration in mice are blocked by the crf, receptor antagonist antalarmin and by crf, receptor knockout  Academic Article
• Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation  Academic Article
• Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors  Academic Article
• Depletion of complement does not impact initiation of xenobiotic-induced autoimmune disease  Academic Article
• Depletion of fat-resident T-reg cells prevents age-associated insulin resistance  Academic Article
• Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
• Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions   Academic Article
• Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland  Academic Article
• Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway  Academic Article
• Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland  Academic Article
• Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes  Academic Article
• Derivation of microglia-free astrocyte cultures from neural stem cells  Academic Article
• Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse-transcriptase and suppress human and feline immunodeficiency virus expression in cultured-cells  Academic Article
• Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease  Academic Article
• Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor  Academic Article
• Design and discovery of N-(2-Methyl-5 '-morpholino-6 '-((tetrahydro-2H-pyran-4-yl)oxy)- 3,3 '-bipyridin -5-yl)-3-(trifluoromethyl)benzamide (RAF709): a potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers  Academic Article
• Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300  Academic Article
• Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives  Academic Article
• Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors  Academic Article
• Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase  Academic Article
• Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant  Academic Article
• Design of high-affinity major histocompatibility complex-specific antagonist peptides that inhibit cytotoxic lymphocyte-t activity - implications for control of viral disease  Academic Article
• Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d  Academic Article
• Design of polydactyl zinc-finger proteins for unique addressing within complex genomes  Academic Article
• Design of potent and proteolytically stable oxyntomodulin analogs  Academic Article
• Design of potent and selective 2-aminobenzimidazole-based p38 alpha MAP kinase inhibitors with excellent in vivo efficacy  Academic Article
• Design, synthesis and SAR of novel glucokinase activators  Academic Article
• Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold  Academic Article
• Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs  Academic Article
• Design, synthesis, and characterization of alpha-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase  Academic Article
• Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation  Academic Article
• Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors  Academic Article
• Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists  Academic Article
• Designing 3-D adipospheres for quantitative metabolic study  Academic Article
• Designing arenaviral vaccines  Academic Article
• Designing small-molecule switches for protein-protein interactions  Academic Article
• Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the central nervous system: Astrocytes fail to express major histocompatibility complex class i and ii molecules  Academic Article
• Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis  Academic Article
• Detecting expression of 5T4 in CTCs and tumor samples from NSCLC patients  Academic Article
• Detecting genetic variation in microarray expression data  Academic Article
• Detection and partial characterization of circulating immune-complexes with solid-phase anti-c3  Academic Article
• Detection of a recombinant murine leukemia virus-related glycoprotein on virus-negative thymoma cells  Academic Article
• Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging  Academic Article
• Detection of h-2 antigens in serum  Academic Article
• Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing  Academic Article
• Detection of low-avidity CD4(+) T cells using recombinant artificial APC: following the antiovalbumin immune response  Academic Article
• Detection of malignant melanoma with monoclonal antibodies  Academic Article
• Detection of naturally occurring antibodies to rna-dependent DNA-polymerase of murine leukemia-virus in kidney eluates of akr mice  Academic Article
• Detection of prion infectivity in fat tissues of scrapie-infected mice  Academic Article
• Detection of transforming oncogenes in rat colon tumors induced by direct perfusion with N-methyl-N-nitrosourea  Academic Article
• Detection of vitronectin mRNA in tissues and cells of the mouse  Academic Article
• Detection, identification, and partial characterization of serine proteases and esterases in biological-systems  Academic Article
• Determinants of P3 amplitude and response to alcohol in Native American Mission Indians  Academic Article
• Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone  Academic Article
• Development and maintenance of a b220(-) memory b cell compartment  Academic Article
• Development and mechanism of γ-secretase modulators for Alzheimer's disease  Academic Article
• Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15  Academic Article
• Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-beta-Hexosaminidase Inhibitors  Academic Article
• Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection  Academic Article
• Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models  Academic Article
• Development of all CD4 T lineages requires nuclear factor TOX  Academic Article
• Development of an affinity chromatography resin for the purification of carcinogen binding proteins from mouse liver  Academic Article
• Development of anti-CD74 antibody-drug conjugates to target glucocorticoids to immune cells  Academic Article
• Development of antigen-specific helper T cell responses in vivo: antigen-specific Th cell subsets  Academic Article
• Development of approaches to improve cell survival in myoblast transfer therapy  Academic Article
• Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens  Academic Article
• Development of chemical probes for investigation of salt-inducible kinase function in vivo  Academic Article
• Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris  Academic Article
• Development of ecdysone-regulated lentiviral vectors  Academic Article
• Development of functionally selective, small molecule agonists at kappa opioid receptors  Academic Article
• Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties  Academic Article
• Development of immature thymocytes - initiation of CD3, CD4, and CD8 acquisition parallels down-regulation of the interleukin-2 receptor alpha-chain  Academic Article
• Development of insulin resistance in mice lacking PGC-1α in adipose tissues  Academic Article
• Development of live-attenuated arenavirus vaccines based on codon deoptimization  Academic Article
• Development of lupus in BXSB mice is independent of IL-4  Academic Article
• Development of oseltamivir phosphonate congeners as anti-influenza agents  Academic Article
• Development of pegylated forms of recombinant rhodosporidium toruloides phenylalanine ammonia-lyase for the treatment of classical phenylketonuria  Academic Article
• Development of proneurogenic, neuroprotective small molecules  Academic Article
• Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p  Academic Article
• Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain  Academic Article
• Developmental biology: The early heart remodelled  Academic Article
• Developmental control of n-cam expression by hox and pax gene-products  Academic Article
• Developmental expression of sorting nexin 3 in the mouse central nervous system  Academic Article
• Developmental expression of the alpha(iel)beta(7) integrin on t-cell receptor-gamma-delta and t-cell receptor-alpha-beta t-cells  Academic Article
• Developmental neurobiology: A genetic cheshire cat?  Academic Article
• Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease  Academic Article
• Developmental regulation of Zbu1, a DNA-binding member of the SWI2/SNF2 family  Academic Article
• Developmental regulation of b lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection  Academic Article
• Developmental regulation of beta 1 integrins during angiogenesis in the central nervous system  Academic Article
• Developmentally distinct th cells control plasma cell production in vivo  Academic Article
• Developmentally ordered appearance of thymocytes expressing different t-cell antigen receptors  Academic Article
• Developmentally regulated use of alternative promoters creates a novel platelet-derived growth-factor receptor transcript in mouse teratocarcinoma and embryonic stem-cells  Academic Article
• Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin tumor-necrosis-factor synthesis at separate points in the signaling pathway  Academic Article
• Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands  Academic Article
• Dhhc5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells  Academic Article
• Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1  Academic Article
• Diabetes insipidus in mice with a mutation in aquaporin-2  Academic Article
• Diced electrophoresis gel assay for screening enzymes with specified activities  Academic Article
• Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice  Academic Article
• Diet and feeding pattern affect the diurnal dynamics of the gut microbiome  Academic Article
• Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or-4 receptors  Academic Article
• Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics  Academic Article
• Differences in experimental tumor-localization of dual-labeled monoclonal-antibody  Academic Article
• Differences in one-way active-avoidance learning in mice of 3 inbred strains  Academic Article
• Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive cd4(+) t-cells by anti-cd4 monoclonal-antibody (gk1.5) in young and aged mice  Academic Article
• Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice  Academic Article
• Differences in the liability to self-administer intravenous cocaine between c57bl/6xsjl and balb/cbyj mice  Academic Article
• Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP  Academic Article
• Different mechanisms of increased luminal stenosis after arterial injury in mice deficient for urokinase- or tissue-type plasminogen activator  Academic Article
• Different pathways mediate virus inducibility of the human ifn-alpha-1 and ifn-beta genes  Academic Article
• Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9  Academic Article
• Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes  Academic Article
• Differential T cell responses to residual viral antigen prolong CD4(+) T cell contraction following the resolution of infection  Academic Article
• Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively  Academic Article
• Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation  Academic Article
• Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen  Academic Article
• Differential effects of a new amphotericin B derivative, MS-8209, on mouse BSE and scrapie: Implications for the mechanism of action of polyene antibiotics  Academic Article
• Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice  Academic Article
• Differential effects of il-12 on the generation of alloreactive ctl mediated by murine and human dendritic cells: A critical role for nitric oxide  Academic Article
• Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice  Academic Article
• Differential effects of morphine, dpdpe, and u-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice  Academic Article
• Differential effects of morphine- and cocaine-induced nnos immunoreactivity in the dentate gyrus of hippocampus of mice lacking mu-opioid receptors  Academic Article
• Differential effects of n-peptidyl-o-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test  Academic Article
• Differential effects of pharmacologic and genetic modulation of NMDA receptor activity on HIV/gp120-induced neuronal damage in an in vivo mouse model  Academic Article
• Differential expression of 2 distinct xenotropic viruses in nzb mice  Academic Article
• Differential expression of the repertoire in in vitro and in vivo responses to minor alloantigens  Academic Article
• Differential gene expression in lps/ifn gamma activated microglia and macrophages: In vitro versus in vivo  Academic Article
• Differential gene expression in the developing lateral geniculate nucleus and medial geniculate nucleus reveals novel roles for Zic4 and Foxp2 in visual and auditory pathway development  Academic Article
• Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis  Academic Article
• Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis  Academic Article
• Differential internalization of hu14.18-il2 immunocytokine by nk and tumor cell: Impact on conjugation, cytotoxicity, and targeting  Academic Article
• Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy  Academic Article
• Differential mechanisms of morphine antinociceptive tolerance revealed in beta arrestin-2 knock-out mice  Academic Article
• Differential modulation by the stress axis of ethanol withdrawal seizure expression in WSP and WSR mice  Academic Article
• Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation  Academic Article
• Differential protective effects of connective tissue growth factor against Aβ neurotoxicity on neurons and glia.  Academic Article
• Differential regulation by multiple promoters of the gene encoding the neuron-restrictive silencer factor  Academic Article
• Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites  Academic Article
• Differential regulation of E2F and Sp1-mediated transcription by G1 cyclins  Academic Article
• Differential regulation of antiviral T-cell immunity results in stable CD8(+) but declining CD4(+) T-cell memory  Academic Article
• Differential regulation of beta-1-adrenergic and beta-2-adrenergic receptor protein and messenger-rna levels by glucocorticoids during 3t3-f442a adipose differentiation  Academic Article
• Differential regulation of cell motility and invasion by fak  Academic Article
• Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation  Academic Article
• Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone  Academic Article
• Differential regulation of vitronectin in mice and humans in vitro  Academic Article
• Differential role of melanocortin receptor subtypes in cachexia  Academic Article
• Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry  Academic Article
• Differential target cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice  Academic Article
• Differential utilization of upstream augs in the beta-secretase mrna suggests that a shunting mechanism regulates translation  Academic Article
• Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in g86r superoxide dismutase transgenic mice  Academic Article
• Differential-effects of cytotactin tenascin fusion proteins on intracellular ph and cell morphology  Academic Article
• Differential-effects of the cytoplasmic domains of cell-adhesion molecules on cell-aggregation and sorting-out  Academic Article
• Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice  Academic Article
• Differentiation of Mycoplasma mycoides subsp. mycoides from certain closely related caprine mycoplasmas by mycoplasmaemia and cross-protection tests in mice  Academic Article
• Differentiation of mouse keratinocytes is accompanied by pkc-dependent changes in ap-1 proteins  Academic Article
• Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTen-dependent mechanism  Academic Article
• Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors  Academic Article
• Diphosphoryl lipid-a from rhodopseudomonas-sphaeroides atcc 17023 blocks induction of cachectin in macrophages by lipopolysaccharide  Academic Article
• Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects  Academic Article
• Direct comparison of Dll1-and Dll4-mediated notch activation levels shows differential lymphomyeloid lineage commitment outcomes  Academic Article
• Direct ex vivo kinetic and phenotypic analyses of cd8(+) t-cell responses induced by DNA immunization  Academic Article
• Direct imaging of interactions between an icosahedral virus and conjugate f-ab fragments by cryoelectron microscopy and x-ray crystallography  Academic Article
• Direct immunofluorescent tissue culture assay for lymphocytic choriomeningitis virus  Academic Article
• Direct induction of cyclin d2 by myc contributes to cell cycle progression and sequestration of p27  Academic Article
• Direct interferon-gamma signalling and cd8(+) t cell memory  Academic Article
• Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe  Academic Article
• Direct regulation of clock expression by rev-erb  Academic Article
• Direct reprogramming of mouse fibroblasts to neural progenitors  Academic Article
• Direct targeting of αvβ3 integrin on tumor cells with a monoclonal antibody, Abegrin™  Academic Article
• Directed enzyme evolution guided by multidimensional analysis of substrate-activity space  Academic Article
• Discovering disease-associated enzymes by proteome reactivity profiling  Academic Article
• Discovering potent and selective reversible inhibitors of enzymes in complex proteomes  Academic Article
• Discovery and characterization of a mammalian amyloid disaggregation activity  Academic Article
• Discovery and characterization of an endogenous CXCR4 antagonist  Academic Article
• Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2  Academic Article
• Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)  Academic Article
• Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability  Academic Article
• Discovery metabolite profiling - forging functional connections between the proteome and metabolome  Academic Article
• Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer  Academic Article
• Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer  Academic Article
• Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia  Academic Article
• Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors  Academic Article
• Discovery of 3-cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo 2,3-b pyridin-5-yObenzamide: a potent, selective, and orally bioavailable retinoic acid receptor related orphan receptor C2 inverse agonist  Academic Article
• Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia  Academic Article
• Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system  Academic Article
• Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer  Academic Article
• Discovery of GlyT1 inhibitors with improved pharmacokinetic properties  Academic Article
• Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia  Academic Article
• Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-m ethyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through structure-based drug design: a high affinity irreversible inhibitor targeting oncogenic EGFR mutants with selectivity over wild-type EGFR  Academic Article
• Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition  Academic Article
• Discovery of a noncovalent, mutant-selective epidermal growth factor receptor inhibitor  Academic Article
• Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomain of CBP/EP300  Academic Article
• Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer  Academic Article
• Discovery of a proneurogenic, neuroprotective chemical  Academic Article
• Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design  Academic Article
• Discovery of a small molecule insulin mimetic with antidiabetic activity in mice  Academic Article
• Discovery of a small-molecule BMP sensitizer for human embryonic stem cell differentiation  Academic Article
• Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors  Academic Article
• Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements  Academic Article
• Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors  Academic Article
• Discovery of matrix metalloproteases selective and activated peptide-doxorubicin prodrugs as anti-tumor agents  Academic Article
• Discovery of native autoantigens via antigen surrogate technology: Application to type 1 diabetes  Academic Article
• Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design  Academic Article
• Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients  Academic Article
• Discovery of potent and bioavailable GSK-3β inhibitors  Academic Article
• Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors  Academic Article
• Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties  Academic Article
• Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators  Academic Article
• Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model  Academic Article
• Discovery of pyrrolo 1,2-b pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors  Academic Article
• Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na(v)1.7 inhibitors with pain efficacy in mice  Academic Article
• Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2)  Academic Article
• Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist  Academic Article
• Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (s1p(4)-r) agonists  Academic Article
• Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)  Academic Article
• Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3  Academic Article
• Discrete BDNF neurons in the paraventricular hypothalamus control feeding and energy expenditure  Academic Article
• Discriminated selection among viral peptides with the appropriate anchor residues - implications for the size of the cytotoxic t-lymphocyte repertoire and control of viral-infection  Academic Article
• Disease accompanying in utero viral infection. The role of maternal antibody in tissue injury after transplacental infection with lymphocytic choriomeningitis virus  Academic Article
• Disease model: Dissecting the pathogenesis of the measles virus  Academic Article
• Disease modifying potential of glatiramer acetate in Huntington's disease  Academic Article
• Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders  Academic Article
• Disialoganglioside gd3 on human-melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis  Academic Article
• Disproportionate inhibition of feeding in a(y) mice by certain stressors: A cautionary note  Academic Article
• Disproportionate recruitment of cd8(+) t cells into the central nervous system by professional antigen-presenting cells  Academic Article
• Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity  Academic Article
• Disruption of Gja8 (α8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation  Academic Article
• Disruption of angiogenesis by pex, a noncatalytic metalloproteinase fragment with integrin binding activity  Academic Article
• Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease  Academic Article
• Disruption of dendritic translation of camkii alpha impairs stabilization of synaptic plasticity and memory consolidation  Academic Article
• Disruption of differentiated functions during viral infection in vivo - v. Mapping of a locus involved in susceptibility of mice to growth hormone deficiency due to persistent lymphocytic choriomeningitis virus infection  Academic Article
• Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure  Academic Article
• Disruption of myd88 signaling suppresses hemophagocytic lymphohistiocytosis in mice  Academic Article
• Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal  Academic Article
• Disruption of the arf transcriptional activator dmp1 facilitates cell immortalization, ras transformation, and tumorigenesis  Academic Article
• Disruption of the arf-mdm2-p53 tumor suppressor pathway in myc-induced lymphomagenesis  Academic Article
• Disruption of the chaperonin containing TCP-1 function affects protein networks essential for rod outer segment morphogenesis and survival  Academic Article
• Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome  Academic Article
• Disruption of the plasminogen activator inhibitor-1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice  Academic Article
• Disruption of tissue-specific fucosyltransferase vii, an enzyme necessary for selectin ligand synthesis, suppresses atherosclerosis in mice  Academic Article
• Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice  Academic Article
• Dissecting influenza virus pathogenesis uncovers a novel chemical approach to combat the infection  Academic Article
• Dissecting the molecular anatomy of persistent infection with lymphocytic choriomeningitis virus  Academic Article
• Dissecting the molecular anatomy of the nervous system: analysis of RNA and protein expression in whole body sections of laboratory animals  Academic Article
• Dissecting the requirements for maintenance of the cmv-specific memory t-cell pool  Academic Article
• Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire  Academic Article
• Dissection of the BCL-2 family signaling network with stabilized alpha-helices of BCL-2 domains  Academic Article
• Dissection of the insulin-sensitizing effect of liver x receptor ligands  Academic Article
• Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice  Academic Article
• Dissociation of locomotor activation and suppression of food intake induced by crf in crfr1-deficient mice  Academic Article
• Dissociation of the effect of aminoglutethimide on corticosterone biosynthesis from ataxic and hypothermic effects in DBA and C57 mice  Academic Article
• Dissociation of the opioid receptor mechanisms that control mechanical and heat pain  Academic Article
• Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)  Academic Article
• Distinct APCs explain the cytokine bias of alpha-galactosylceramide variants in vivo  Academic Article
• Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region  Academic Article
• Distinct TCR signaling pathways drive proliferation and cytokine production in T cells  Academic Article
• Distinct and opposing roles for Rab27a/MIph/MyoVa and Rab27b/Munc13-4 in mast cell secretion  Academic Article
• Distinct antithrombotic consequences of platelet glycoprotein Ibα and VI deficiency in a mouse model of arterial thrombosis  Academic Article
• Distinct conformational spectrum of homologous multidrug ABC transporters  Academic Article
• Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III  Academic Article
• Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease  Academic Article
• Distinct endocytic mechanisms of cd22 (siglec-2) and siglec-f reflect roles in cell signaling and innate immunity  Academic Article
• Distinct footprints of tcr engagement with highly homologous ligands  Academic Article
• Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus  Academic Article
• Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure  Academic Article
• Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors  Academic Article
• Distinct rate and patterns of human CD4+ T-cell depletion in hu-PBL-SCID mice infected with different isolates of the human immunodeficiency virus  Academic Article
• Distinct requirements for deletion versus anergy during CD8 T cell peripheral tolerance in vivo  Academic Article
• Distinct role of long 3 ' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons  Academic Article
• Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci  Academic Article
• Distinct roles for astrocyte alpha v beta 5 and alpha v beta 8 integrins in adhesion and migration  Academic Article
• Distinct roles for somatically and dendritically synthesized brain-derived neurotrophic factor in morphogenesis of dendritic spines  Academic Article
• Distinct roles of cytoskeletal components in immunological synapse formation and directed secretion  Academic Article
• Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapse  Academic Article
• Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature b cells  Academic Article
• Distinct spatio-temporal Ca(2+) signaling elicited by integrin alpha 2 beta 1 and glycoprotein VI under flow  Academic Article
• Distinction between malignant l cells and normal mouse fibroblasts by rosette formation with sheep red blood-cells  Academic Article
• Distinctions in beta-adrenergic-receptor interactions with the magnesium-guanine nucleotide coupling proteins in turkey erythrocyte and s49-lymphoma membranes  Academic Article
• Distortion of cell functions by noncytotoxic viruses  Academic Article
• Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide  Academic Article
• Distribution of endotoxin (lipopolysaccharide) in tissues of lipopolysaccharide-responsive and lipopolysaccharide-unresponsive mice  Academic Article
• Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes  Academic Article
• Distribution of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected trigeminal ganglia in the mouse  Academic Article
• Distribution of vitronectin mRNA during murine development  Academic Article
• Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists  Academic Article
• Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors  Academic Article
• Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor  Academic Article
• Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα  Academic Article
• Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis  Academic Article
• Diverse roles of Eph/ephrin signaling in the mouse lens  Academic Article
• Diversity of T-cell receptors in virus-specific cytotoxic T lymphocytes recognizing three distinct viral epitopes restricted by a single major histocompatibility complex molecule  Academic Article
• Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis  Academic Article
• Division of labor of schwann cell integrins during migration on peripheral nerve extracellular matrix ligands  Academic Article
• Do t cells need endogenous peptides for activation?  Academic Article
• Does preferential Th subset activation contribute to the murine acquired immunodeficiency disease (MAIDS)?  Academic Article
• Does the major histocompatibility complex serve as a specific receptor for semliki forest virus  Academic Article
• Does toll-like receptor 3 play a biological role in virus infections?  Academic Article
• Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor  Academic Article
• Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3  Academic Article
• Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation  Academic Article
• Dominant cataracts result from incongruous mixing of wild-type lens connexins  Academic Article
• Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis  Academic Article
• Dopamine d1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral-responses  Academic Article
• Dopamine neurotransmission is involved in the attenuating effects of 5-ht3 receptor antagonist mdl 72222 on acute methamphetamine-induced locomotor hyperactivity in mice  Academic Article
• Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons  Academic Article
• Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice  Academic Article
• Dorsal raphe dopamine neurons modulate arousal and promote wakefulness by salient stimuli  Academic Article
• Dose response and timing effects in the therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate  Academic Article
• Dose- and time-dependent bimodal effects of kappa-opioid agonists on locomotor activity in mice  Academic Article
• Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake  Academic Article
• Double-strand DNA breaks recruit the centromeric histone CENP-A  Academic Article
• Double-stranded rna-mediated tlr3 activation is enhanced by cd14  Academic Article
• Down-regulation of MHC class-I antigen in insulinoma cells controlled by the R1 element of the H-2 enhancer  Academic Article
• Down-regulation of beta(3) adrenoreceptor gene expression in brown fat cells is transient and recovery is dependent upon a short-lived protein factor  Academic Article
• Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice  Academic Article
• Down-regulation of the major histocompatibility complex class-I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding  Academic Article
• Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin  Academic Article
• Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice  Academic Article
• Downregulation of transcription factor sox2 in cancer stem cells suppresses growth and metastasis of lung cancer  Academic Article
• Downregulation of tumor growth and invasion by redox-active nanoparticles  Academic Article
• Doxorubicin conjugated with a monoclonal-antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude-mice  Academic Article
• Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies  Academic Article
• Drug target validation: lethal infection blocked by inducible peptide  Academic Article
• Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition  Academic Article
• DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes  Academic Article
• DsAAV8-mediated gene transfer and beta-cell expression of IL-4 and beta-cell growth factors are capable of reversing early-onset diabetes in NOD mice  Academic Article
• Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression  Academic Article
• Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo  Academic Article
• Dual control of myc expression through a single DNA-binding site targeted by ets family proteins and e2f-1  Academic Article
• Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like morris water maze deficits in mice  Academic Article
• Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice  Academic Article
• Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: Actin depolymerization by Ca2+-alpha-actinin and polymerization by rho  Academic Article
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• Early postnatal plasticity in neocortex of fmr1 knockout mice  Academic Article
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• Effect of bone morphogenetic protein-2-expressing muscle-derived cells on healing of critical-sized bone defects in mice  Academic Article
• Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B-1 cell survival in transgenic mice expressing a low level of IgK-reactive macroself antigen  Academic Article
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• Effective inhibition of HBV replication in vivo by anti-HBx short hairpin RNAs  Academic Article
• Effective replication of human influenza viruses in mice lacking a major alpha 2,6 sialyltransferase  Academic Article
• Effective therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate  Academic Article
• Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL  Academic Article
• Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4  Academic Article
• Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express il-4  Academic Article
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• Effector functions of a monoclonal aglycosylated mouse igg2a - binding and activation of complement component c1 and interaction with human monocyte fc-receptor  Academic Article
• Effector role of blood monocytes in experimental visceral leishmaniasis  Academic Article
• Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production  Academic Article
• Effects of anti-Lyt-2 and anti-L3T4 monoclonal antibodies on the function of cytotoxic T lymphocyte/helper T lymphocyte hybrid T cell clones  Academic Article
• Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice  Academic Article
• Effects of antiproliferative cyclic-amp on interleukin 2-stimulated gene-expression  Academic Article
• Effects of antisense c-myb oligonucleotides on vascular smooth-muscle cell-proliferation and response to vessel wall injury  Academic Article
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• Effects of blocking individual maturation cleavages in murine leukemia virus gag  Academic Article
• Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice  Academic Article
• Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta  Academic Article
• Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse  Academic Article
• Effects of concanavalin a on mobility of lymphocyte surface receptors  Academic Article
• Effects of coptis japonica on morphine-induced conditioned place preference in mice  Academic Article
• Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch  Academic Article
• Effects of energy intake on type 1 plasminogen activator inhibitor levels in glomeruli of lupus-prone B/W mice  Academic Article
• Effects of environmental enrichment on gene expression in the brain  Academic Article
• Effects of ginseng total saponin on cocaine-induced hyperactivity and conditioned place preference in mice  Academic Article
• Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice  Academic Article
• Effects of hydroxamate metalloendoprotease inhibitors on botulinum neurotoxin a poisoned mouse neuromuscular junctions  Academic Article
• Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase  Academic Article
• Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells  Academic Article
• Effects of lurasidone in behavioral models of depression. Role of the 5-HT7 receptor subtype  Academic Article
• Effects of morphine on pentobarbital-induced responses in mu-opioid receptor knockout mice  Academic Article
• Effects of naltrexone and acamprosate on alcohol-induced ngfi-a expression in mouse brain  Academic Article
• Effects of sodium metaperiodate on t and b lymphocytes  Academic Article
• Effects of soluble TNF receptor treatment on lipopolysaccharide-induced myocardial cytokine expression  Academic Article
• Effects of the endogenous PPAR-alpha agonist, oleoylethanolamide on MDMA-induced cognitive deficits in mice  Academic Article
• Effects of the ginsenosides rg(1) and rb-1 on morphine-induced hyperactivity and reinforcement in mice  Academic Article
• Effects of the herbal extract PC-SPES on microtubule dynamics and paclitaxel-mediated prostate tumor growth inhibition  Academic Article
• Effects of the specific alpha 4 beta 2 nachr antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice  Academic Article
• Effects of topical Janus kinase inhibition on ocular surface inflammation and immunity  Academic Article
• Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs  Academic Article
• Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer  Academic Article
• Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination  Academic Article
• Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia  Academic Article
• Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice  Academic Article
• Efficiency and effectiveness of cloned virus-specific cytotoxic T lymphocytes in vivo  Academic Article
• Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes  Academic Article
• Efficient bone formation by gene transfer of human LIM mineralization protein-3  Academic Article
• Efficient formation of uniform-sized embryoid bodies using a compartmentalized microchannel device  Academic Article
• Efficient gene delivery to human and rodent islets with double-stranded (ds) aav-based vectors  Academic Article
• Efficient peripheral clonal elimination of b lymphocytes in mrl/lpr mice bearing autoantibody transgenes  Academic Article
• Efficient preparation of site-specific antibody-drug conjugates using cysteine insertion  Academic Article
• Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2  Academic Article
• Efficient t cell activation via a toll-interleukin 1 receptor-independent pathway  Academic Article
• Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone-marrow transduced by a retroviral vector  Academic Article
• Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells  Academic Article
• Egr-1 induces darpp-32 expression in striatal medium spiny neurons via a conserved intragenic element  Academic Article
• Electrical remodeling of preoptic GABAergic neurons involves the Kv1.5 subunit  Academic Article
• Electron microscopic image analysis of cardiac gap junction membrane crystals  Academic Article
• Electron microscopic localization of corticotropin-releasing factor (CRF) and CRF receptor in rat and mouse central nucleus of the amygdala  Academic Article
• Electron-microscopic analysis of modulation of lymphocyte receptor mobility  Academic Article
• Electronically subtracting expression patterns from a mixed cell population  Academic Article
• Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture  Academic Article
• Electrophysiology of purkinje neurons in weaver mouse - iontophoresis of neurotransmitters and cyclic nucleotides, and stimulation of nucleus locus coeruleus  Academic Article
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• Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice  Academic Article
• Elevated expression of transforming growth factor-beta in adipose tissue from obese mice  Academic Article
• Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation  Academic Article
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• Elicitation of structure-specific antibodies by epitope scaffolds  Academic Article
• Elimination of dendritic spines with long-term memory is specific to active circuits  Academic Article
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• Elimination of macrophage-specific apolipoprotein e reduces diet-induced atherosclerosis in c57bl/6j male mice  Academic Article
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• Embryo spacing and implantation timing are differentially regulated by LPA3-mediated lysophosphatidic acid signaling in mice  Academic Article
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• Endogenous molecules stimulating n-acylethanolamine-hydrolyzing acid amidase (naaa)  Academic Article
• Endogenous oncornaviral gene-expression in adult and fetal mice - quantitative, histologic, and physiologic studies of major viral glycoprotein, gp70  Academic Article
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• Endothelial beta4 integrin is predominantly expressed in arterioles, where it promotes vascular remodeling in the hypoxic brain  Academic Article
• Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection  Academic Article
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• Endotoxin interactions with lipopolysaccharide-responsive cells  Academic Article
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• Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice  Academic Article
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• Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test  Academic Article
• Enhanced immunogenicity of the pre-S region of hepatitis B surface antigen  Academic Article
• Enhanced in situ detection of beta-glucuronidase activity in murine tissue  Academic Article
• Enhanced iodination of thyroglobulin facilitates processing and presentation of a cryptic pathogenic peptide  Academic Article
• Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice  Academic Article
• Enhanced major histocompatibility complex class i binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide  Academic Article
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• Enhanced mucosal immunoglobulin a response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system  Academic Article
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• Enhanced oxidative phosphorylation in NKT cells is essential for their survival and function  Academic Article
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• Enhanced thrombosis in atherosclerosis-prone mice is associated with increased arterial expression of plasminogen activator inhibitor-1  Academic Article
• Enhanced tumorigenicity of an Epstein-Barr virus-transformed lymphoblastoid cell line is associated with a unique 1:18 chromosomal translocation and decreased expression of lymphocyte function associated antigen-1a (CD11A)  Academic Article
• Enhancement of anti-tumor immunity by injection of fibroblasts genetically engineered to produce IL-12 and to express CD70  Academic Article
• Enhancement of antibody-dependent cytotoxicity with a chimeric anti-gd2 antibody  Academic Article
• Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells  Academic Article
• Enhancement of autoimmune-disease using recombinant vaccinia virus encoding myelin proteolipid protein  Academic Article
• Enhancement of bone healing based on ex vivo gene therapy using human muscle-derived cells expressing bone morphogenetic protein 2  Academic Article
• Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P(1) antagonist in vivo  Academic Article
• Enhancement of experimental allergic encephalomyelitis (eae) by DNA immunization with myelin proteolipid protein (plp) plasmid DNA  Academic Article
• Enhancement of fgf-like polypeptides in the retinae of newborn mice exposed to hyperoxia  Academic Article
• Enhancement of infectivity and oncogenicity of a murine leukemia-virus in adult mice by x-irradiation  Academic Article
• Enhancement of metastasis development by bcg immunotherapy  Academic Article
• Enhancement of reaginic and hemagglutinating antibody production by an extract of Bordetella pertussis containing histamine sensitizing factor  Academic Article
• Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program  Academic Article
• Enhancing antibody - a novel component of the immune-response  Academic Article
• Enhancing nicotine vaccine immunogenicity with liposomes  Academic Article
• Enhancing or suppressive effects of antibodies on processing of a pathogenic T cell epitope in thyroglobulin  Academic Article
• Enhancing t cell activation and antiviral protection by introducing the hiv-1 protein transduction domain into a DNA vaccine  Academic Article
• Enrichment of regulatory signals in conserved non-coding genomic sequence  Academic Article
• Enrichment of viable lymphocytes in defined cycle phases by sorting on the basis of pulse width of axial light extinction  Academic Article
• Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells  Academic Article
• Enterotoxin residues determining t-cell receptor v-beta binding-specificity  Academic Article
• Entry versus blockade of brain infection following oral or intraperitoneal scrapie administration: Role of prion protein expression in peripheral nerves and spleen  Academic Article
• Enumeration and characterization of memory cells in the TH compartment  Academic Article
• Enumeration and functional evaluation of virus-specific cd4(+) and cd8(+) t cells in lymphoid and peripheral sites of coxsackievirus b3 infection  Academic Article
• Envelope exchange for the generation of live-attenuated arenavirus vaccines  Academic Article
• Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N(ω)-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus  Academic Article
• Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals  Academic Article
• EphA2 and Src regulate equatorial cell morphogenesis during lens development  Academic Article
• EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens  Academic Article
• Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors  Academic Article
• Epigenetic changes at gene promoters in response to immune activation in utero  Academic Article
• Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation  Academic Article
• Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories  Academic Article
• Epigenetic regulation of pluripotency and differentiation  Academic Article
• Epithelial membrane protein-1 is a biomarker of gefitinib resistance  Academic Article
• Epithelial p38 alpha controls immune cell recruitment in the colonic mucosa  Academic Article
• Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence  Academic Article
• Epitopes on proliferating cell nuclear antigen recognized by human lupus autoantibody and murine monoclonal antibody  Academic Article
• Epstein-Barr virus nuclear protein 2 is a critical determinant for tumor growth in SCID mice and for transformation in vitro  Academic Article
• Epstein-Barr virus-induced human B-cell lymphomas in SCID mice reconstituted with human peripheral blood leukocytes  Academic Article
• Epstein-Barr-virus complement C3d receptor is an interferon-alpha receptor  Academic Article
• Epstein-barr virus small rnas potentiate tumorigenicity of burkitt lymphoma cells independently of an effect on apoptosis  Academic Article
• Eradication of established human-melanoma tumors in nude-mice by antibody-directed effector-cells  Academic Article
• Eradication of human hepatic and pulmonary melanoma metastases in scid mice by antibody-interleukin 2 fusion proteins  Academic Article
• Erbb2 regulates neuromuscular synapse formation and is essential for muscle spindle development  Academic Article
• Ercc1/xpf removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes  Academic Article
• Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders  Academic Article
• Escherichia coli infection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD). B6 (Idd10/Idd18) mice  Academic Article
• Esophageal muscle physiology and morphogenesis require assembly of a collagen XIX-rich basement membrane zone  Academic Article
• Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex  Academic Article
• Essential function of NHE8 in mouse retina demonstrated by AAV-mediated CRISPR/Cas9 knockdown  Academic Article
• Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus  Academic Article
• Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues  Academic Article
• Essential role of Stat3 in PI3K-induced oncogenic transformation  Academic Article
• Essential role of growth hormone in ischemia-induced retinal neovascularization  Academic Article
• Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus  Academic Article
• Essential role of phospholipase c gamma 2 in early b-cell development and myc-mediated lymphomagenesis  Academic Article
• Essential role of stromally induced hedgehog signaling in B-cell malignancies  Academic Article
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• Establishment of HIV-1 resistance in CD4(+) T cells by genome editing using zinc-finger nucleases  Academic Article
• Estimation of relative antibody affinity at level of antibody-secreting cell during maturation of immune-response  Academic Article
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• Estrogen receptor subtypes and afferent signaling in the bladder  Academic Article
• Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription  Academic Article
• Estrogen-related receptor gamma promotes mesenchymal-to-epithelial transition and suppresses breast tumor growth  Academic Article
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• Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors  Academic Article
• Ethanol consumption in mice: Relationships with circadian period and entrainment  Academic Article
• Etiopathogenesis of murine sle  Academic Article
• Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains  Academic Article
• Evaluating the immunogenicity and protective efficacy of a DNA vaccine encoding lassa virus nucleoprotein  Academic Article
• Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors  Academic Article
• Evaluation of a reductively activated duocarmycin prodrug against murine and human solid cancers  Academic Article
• Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids  Academic Article
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• Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus  Academic Article
• Evidence that TRPC1 is involved in hippocampal glutamate-induced cell death  Academic Article
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• Expression of human platelet glycoprotein Ib alpha in transgenic mice  Academic Article
• Expression of leukemogenic recobinant viruses associated with a recessive gene in hrs-j mice  Academic Article
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• Expression of raf family protooncogenes in normal mouse-tissues  Academic Article
• Expression of selected antigens on surface of cultured neural cells  Academic Article
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• Expression of t-cell receptor genes in an antigen-specific hybridoma and radiation-induced variants  Academic Article
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• Extracellular processing of peptide antigens that bind class I major histocompatibility molecules  Academic Article
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• Gap junctional coupling in lenses lacking alpha(3) connexin  Academic Article
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• Genetic approaches to memory storage  Academic Article
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• Genetic deletion of NR3A accelerates glutamatergic synapse maturation  Academic Article
• Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum  Academic Article
• Genetic differences in behavioral sensitivity to a neuroactive steroid  Academic Article
• Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal  Academic Article
• Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice  Academic Article
• Genetic disorders associated with atp binding cassette cholesterol transporters  Academic Article
• Genetic disruption of gamma-melanocyte-stimulationg hormone signaling leads to salt-sensitive hypertension in the mouse  Academic Article
• Genetic dissection of innate immunity to infection: The mouse cytomegalovirus model  Academic Article
• Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis  Academic Article
• Genetic diversity of murine rheumatoid factors  Academic Article
• Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens  Academic Article
• Genetic factors influence cataract formation in α(3) connexin knockout mice  Academic Article
• Genetic informational rna is not required for recombinant prion infectivity  Academic Article
• Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes  Academic Article
• Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes  Academic Article
• Genetic loss of FAAH compromises male fertility in mice  Academic Article
• Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling  Academic Article
• Genetic modulation of T cell receptor gene segment usage during somatic recombination  Academic Article
• Genetic reassortants of lymphocytic choriomeningitis virus - unexpected disease and mechanism of pathogenesis  Academic Article
• Genetic regulation of behavioral and neuronal responses to fluoxetine  Academic Article
• Genetic regulation of commitment to interleukin 4 production by a cd4(+) t cell-intrinsic mechanism  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). I. H-2 restriction of the murine humoral immune response to the a and d determinants of HBsAg  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). II. Qualitative characteristics of the humoral immune response to the a, d, and y determinants of HBsAg  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). III. Circumvention of nonresponsiveness in mice bearing HBsAg nonresponder haplotypes  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). VI. T cell fine specificity  Academic Article
• Genetic reprogramming of tumor cells by zinc finger transcription factors  Academic Article
• Genetic risk prediction and neurobiological understanding of alcoholism  Academic Article
• Genetic studies in systemic autoimmunity and aging  Academic Article
• Genetic studies of auto-immunity and retrovirus expression in crosses of new-zealand black mice .2. Viral envelope glycoprotein gp70  Academic Article
• Genetic susceptibility to silver-induced anti-fibrillarin autoantibodies in mice  Academic Article
• Genetic-control of immunoglobulin-synthesis  Academic Article
• Genetic-regulation of the immune-response to hepatitis-b surface-antigen (hbsag) .5. T-cell proliferative response and cellular interactions  Academic Article
• Genetical genomics: spotlight on QTL hotspots  Academic Article
• Genetically encoded and post-translationally modified forms of a major histocompatibility complex class i-restricted antigen bearing a glycosylation motif are independently processed and co-presented to cytotoxic t lymphocytes  Academic Article
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• Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis  Academic Article
• Genetics of SLE in mice  Academic Article
• Genetics of systemic autoimmunity and glomerulonephritis in mouse models of lupus  Academic Article
• Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming  Academic Article
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• Genome-wide gain-of-function screen identifies novel regulators of pluripotency  Academic Article
• Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intake  Academic Article
• Genome-wide gene expression profiles of the developing mouse hippocampus  Academic Article
• Genome-wide haplotype association mapping in mice identifies a genetic variant in cer1 associated with bmd and fracture in southern chinese women  Academic Article
• Genome-wide identification of bcl11b gene targets reveals role in brain-derived neurotrophic factor signaling  Academic Article
• Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse  Academic Article
• Genomewide association analysis in diverse inbred mice: Power and population structure  Academic Article
• Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system  Academic Article
• Genomic and biological variation among commonly used lymphocytic choriomeningitis virus-strains  Academic Article
• Genomic characterization of the lysophosphatidic acid receptor gene, lPA2/Edg4, and identification of a frameshift mutation in a previously characterized cDNA  Academic Article
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• Genomic organization and expression of b-cell and t-cell antigen receptor genes in murine lupus  Academic Article
• Genomic organization and sequence of t-cell receptor beta-chain constant-region and joining-region genes  Academic Article
• Germline deletion of Igh 3 ' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus  Academic Article
• Germline diversity within the mouse igk-v9 gene family  Academic Article
• Germline exclusion of Cks1 in the mouse reveals a metaphase I role for Cks proteins in male and female meiosis  Academic Article
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• Ghrelin is dispensable for embryonic pancreatic islet development and differentiation  Academic Article
• Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants  Academic Article
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• Ghrelin prevents cisplatin-induced testicular damage by facilitating repair of DNA double strand breaks through activation of p53 in mice  Academic Article
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• Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging  Academic Article
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• Glial membranes at the node of Ranvier prevent neurite outgrowth  Academic Article
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• Glioma-induced remodeling of the neurovascular unit  Academic Article
• Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study  Academic Article
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• Global gene expression analysis of the developing postnatal mouse retina  Academic Article
• Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution  Academic Article
• Global profiling of dynamic protein palmitoylation  Academic Article
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• Hepatitis-B virus immunopathogenesis  Academic Article
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• Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants  Academic Article
• Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates  Academic Article
• Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons  Academic Article
• Hippocampal c-Fos activation in normal and LPA1-null mice after two object recognition tasks with different memory demands  Academic Article
• Hippocampal dopamine/DRD1 signaling dependent on the ghrelin receptor  Academic Article
• Hippocampal phenotypes in kalirin-deficient mice  Academic Article
• Histamine hypersensitivity in mice induced by Bordetella pertussis or pharmacologic beta adrenergic blockade. Effects of adrenergic, cholinergic, and other drugs  Academic Article
• Histamine influences body temperature by acting at h1 and h3 receptors on distinct populations of preoptic neurons  Academic Article
• Histidine-rich glycoprotein binds to DNA and Fc gamma RI and potentiates the ingestion of apoptotic cells by macrophages  Academic Article
• Histocompatibility complex and virus infection latency and activation  Academic Article
• Histocompatibility-linked genetic-control of disease susceptibility - murine lymphocytic choriomeningitis virus-infection  Academic Article
• Histocompatibility-linked genetic-control of specific immune-responses to viral-infection  Academic Article
• Histone H2A-mediated transient cytokine gene delivery induces efficient antitumor responses in murine neuroblastoma  Academic Article
• Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of huntington's disease  Academic Article
• Histone deacetylase inhibitor suppression of auto antibody-mediated arthritis in mice via regulation of p16(INK4a) and p21(WAF1/Cip1) expression  Academic Article
• Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock  Academic Article
• Histone posttranslational modifications in schizophrenia  Academic Article
• Histopathological changes in mice treated with extracts of the histamine-sensitizing factor of Bordetella pertussis  Academic Article
• Hit-to-lead studies for the antimalarial tetrahydroisoquinolone carboxanilides  Academic Article
• Hiv type 1 env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies  Academic Article
• Hiv-1 env(gp140) trimers elicit neutralizing antibodies without efficient induction of conformational antibodies  Academic Article
• HlF-2 alpha deletion promotes kras-driven lung tumor development  Academic Article
• Hla-a2-restricted protection against lethal lymphocytic choriomeningitis  Academic Article
• Homeostasis of memory T cells  Academic Article
• Homeostasis of naive and memory t cells  Academic Article
• Homeostasis of v(alpha)14i nkt cells  Academic Article
• Homeostatic proliferation of mature T cells  Academic Article
• Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix  Academic Article
• Homophilic and heterophilic binding activities of nr-cam, a nervous-system cell-adhesion molecule  Academic Article
• Homophilic interaction of junctional adhesion molecule  Academic Article
• Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation  Academic Article
• Horse prion protein NMR structure and comparisons with related variants of the mouse prion protein  Academic Article
• Host acid sphingomyelinase regulates microvascular function not tumor immunity  Academic Article
• Host and virus factors associated with CNS cellular tropism leading to encephalomyelitis or demyelination induced by the JHM strain of mouse hepatitis virus  Academic Article
• Host endothelial S1PR(1) regulation of vascular permeability modulates tumor growth  Academic Article
• Host genetic-control of mouse hepatitis-virus type-4 (jhm strain) replication .1. Restriction of virus amplification and spread in macrophages from resistant mice  Academic Article
• Host immunoglobulin-g and complement deposits in choroid-plexus during spontaneous immune complex disease  Academic Article
• Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4  Academic Article
• Host-like carbohydrates promote bloodstream survival of Vibrio vulnificus in vivo  Academic Article
• Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic New World clade B arenaviruses  Academic Article
• Host-virus interactions during malaria infection in hepatitis B virus transgenic mice  Academic Article
• How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model  Academic Article
• Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis  Academic Article
• Hsk1-Dfp1/Him1, the Cdc7-Dbf4 kinase in Schizosaccharomyces pombe, associates with Swi1, a component of the replication fork protection complex  Academic Article
• Hsp90-cdc37 chaperone complex regulates ulk1-and atg13-mediated mitophagy  Academic Article
• Human CD22 inhibits murine B cell receptor activation in a human CD22 transgenic mouse model  Academic Article
• Human CD8 transgene regulation of HLA recognition by murine T cells  Academic Article
• Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation  Academic Article
• Human IL-1ra gene transfer into human synovial fibroblasts is chondroprotective  Academic Article
• Human adult tonsil xenotransplantation into SCID mice for studying human immune responses and B cell lymphomagenesis  Academic Article
• Human and laboratory rodent low response to alcohol: Is better consilience possible?  Academic Article
• Human and mouse monoclonal-antibodies by repertoire cloning  Academic Article
• Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro  Academic Article
• Human autoantibody recognition of DNA  Academic Article
• Human beta 2-adrenergic receptor/gs alpha fusion protein, expressed in 2 ras-dependent murine carcinoma cell lines, prevents tumor growth in syngeneic mice  Academic Article
• Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus  Academic Article
• Human cord blood progenitors sustain thymic T-cell development and a novel form of angiogenesis  Academic Article
• Human cytotoxic t-cells suppress the growth of spontaneous melanoma metastases in scid/hu mice  Academic Article
• Human cytotoxic t-lymphocyte repertoire to influenza a viruses  Academic Article
• Human endothelial cells produce IL-6. Lack of responses to exogenous IL-6  Academic Article
• Human gene essentiality  Academic Article
• Human immunodeficiency virus infection of human cells transplanted to severe combined immunodeficient mice  Academic Article
• Human immunodeficiency virus infection of human-PBL-SCID mice  Academic Article
• Human immunodeficiency virus matrix tyrosine phosphorylation: Characterization of the kinase and its substrate requirements  Academic Article
• Human immunodeficiency virus type 1 infection of neonatal severe combined immunodeficient mice xenografted with human cord blood cells  Academic Article
• Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons  Academic Article
• Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment  Academic Article
• Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin  Academic Article
• Human melanoma-associated antigens - role of carbohydrate in shedding and cell-surface expression  Academic Article
• Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis  Academic Article
• Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes  Academic Article
• Human monoclonal antibodies: Recent achievements  Academic Article
• Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis  Academic Article
• Human nop5/nop58 is a component common to the box c/d small nucleolar ribonucleoproteins  Academic Article
• Human pancreatic beta-like cells converted from fibroblasts  Academic Article
• Human periprosthetic tissues implanted in severe combined immunodeficient mice respond to gene transfer of a cytokine inhibitor  Academic Article
• Human pluripotent stem cells: decoding the naïve state  Academic Article
• Human recombinant antimannan immunoglobulin g1 antibody confers resistance to hematogenously disseminated candidiasis in mice  Academic Article
• Human recombinant erythropoietin promotes differentiation of murine megakaryocytes in vitro  Academic Article
• Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis  Academic Article
• Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells  Academic Article
• Human-melanoma antigen o-acetylated ganglioside-gd3 is recognized by cancer-antennarius lectin  Academic Article
• Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins  Academic Article
• Human/mouse cross-reactive anti-VEGF receptor 2 recombinant antibodies selected from an immune b9 allotype rabbit antibody library  Academic Article
• Human/mouse interleukin-1 receptor/receptor accessory protein interactions in IL-1β-induced NFκB activation  Academic Article
• Humanized IgG(1) variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates  Academic Article
• Humanized mice reveal differential immunogenicity of cells derived from autologous induced pluripotent stem cells  Academic Article
• Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease  Academic Article
• Huntington's disease is a disorder of the corpus striatum: focus on Rhes (Ras homologue enriched in the striatum)  Academic Article
• Hybrid T-reg cells: steel frames and plastic exteriors  Academic Article
• Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer  Academic Article
• Hybridoma antibodies to human von Willebrand factor. I. Characterization of seven clones  Academic Article
• Hydrazone ligation strategy to assemble multifunctional viral nanoparticles for cell imaging and tumor targeting  Academic Article
• Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection  Academic Article
• Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase  Academic Article
• Hydrogen peroxide-supported oxidation of ng-hydroxy-l-arginine by nitric oxide synthase  Academic Article
• Hydrogen sulfide-mechanisms of toxicity and development of an antidote  Academic Article
• Hydrogen-ions have multiple effects on the excitability of cultured mammalian neurons  Academic Article
• Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase  Academic Article
• Hydrolytically activated etoposide prodrugs inhibit mdr-1 function and eradicate established mr-1 multidrug-resistant t-cell leukemia  Academic Article
• Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors  Academic Article
• Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker  Academic Article
• Hyper telomere recombination accelerates replicative senescence and may promote premature aging  Academic Article
• Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver  Academic Article
• Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis  Academic Article
• Hyperactive Himar1 transposase mediates transposition in cell culture and enhances gene expression in vivo  Academic Article
• Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of c. Elegans bardet-biedl syndrome mutants  Academic Article
• Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant  Academic Article
• Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype  Academic Article
• Hyperresponsive febrile reactions to interleukin (IL) 1α and IL-1β, and altered brain cytokine mRNA and serum cytokine levels, in IL-1β-deficient mice  Academic Article
• Hypersensitive cytokine response to beta-amyloid 25-35 in astroglial cells from IL-1 receptor type I-deficient mice  Academic Article
• Hypersensitivity to histamine and systemic anaphylaxis in mice with pharmacologic beta adrenergic blockade: protection by nucleotides  Academic Article
• Hypersusceptibility to vesicular stomatitis virus infection in dicer1-deficient mice is due to impaired mir24 and mir93 expression  Academic Article
• Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger  Academic Article
• Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area  Academic Article
• Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide y and agouti gene-related protein systems  Academic Article
• Hypocretins/orexins as integrators of physiological information: Lessons from mutant animals  Academic Article
• Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner  Academic Article
• Hypothalamic and dietary control of temperature-mediated longevity  Academic Article
• Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior  Academic Article
• Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor  Academic Article
• Hypothalamic-pituitary-adrenal axis disregulation in PrPC-null mice  Academic Article
• Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation  Academic Article
• I787 provides signals for c-kit receptor internalization and functionality that control mast cell survival and development  Academic Article
• IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis  Academic Article
• ICAM-1 dependent pathway is not involved in the development of neuronal apoptosis after transient focal cerebral ischemia  Academic Article
• ICOS controls effector function but not trafficking receptor expression of kidney-infiltrating effector T cells in murine lupus  Academic Article
• ICOS-dependent extrafollicular helper T cells elicit igg production via IL-21 in systemic autoimmunity  Academic Article
• IFITM proteins restrict antibody-dependent enhancement of dengue virus infection  Academic Article
• IFITM3 limits the severity of acute influenza in mice  Academic Article
• IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis  Academic Article
• IGF1R-and ROR1-specific CAR T cells as a potential therapy for high risk sarcomas  Academic Article
• IKK beta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis  Academic Article
• IKK beta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNF alpha  Academic Article
• IKKi/IKK epsilon plays a key role in integrating signals induced by pro-inflammatory stimuli  Academic Article
• IL-1/IL-1ra balance in the brain revisited - Evidence from transgenic mouse models  Academic Article
• IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection  Academic Article
• IL-12 gene therapy using direct injection of tumors with genetically engineered autologous fibroblasts  Academic Article
• IL-12-engineered dendritic cells serve as effective tumor vaccine adjuvants in vivo  Academic Article
• IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis  Academic Article
• IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model  Academic Article
• IL-1β induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons  Academic Article
• IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor α subunit CD25  Academic Article
• IL-2/anti-IL-2 complex attenuates renal ischemia-reperfusion injury through expansion of regulatory T cells  Academic Article
• IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms  Academic Article
• IL-6 is essential in TNF-α-induced fever  Academic Article
• IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase  Academic Article
• IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis  Academic Article
• IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R  Academic Article
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• IL-Y, a synthetic member of the IL-12 cytokine family, suppresses the development of type 1 diabetes in NOD mice  Academic Article
• IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis  Academic Article
• IMD-0354 targets breast cancer stem cells: a novel approach for an adjuvant to chemotherapy to prevent multidrug resistance in a murine model  Academic Article
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• IP3 3-kinase B prevents bone marrow failure  Academic Article
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• IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation  Academic Article
• IRhom2 is required for the secretion of mouse TNFα  Academic Article
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• Id2 is dispensable for myc-induced lymphomagenesis  Academic Article
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• Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells  Academic Article
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• Identification and characterization of single chain anti-cocaine catalytic antibodies  Academic Article
• Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins  Academic Article
• Identification and characterization of the first small molecule inhibitor of MDMX  Academic Article
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• Identification and design of p53-derived HLA-A2-binding peptides with increased CTL immunogenicity  Academic Article
• Identification and expression of neu4, a novel murine sialidase  Academic Article
• Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing  Academic Article
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• Identification of 2 protein-kinases that phosphorylate the neural cell-adhesion molecule, n-cam  Academic Article
• Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
• Identification of 2-[2-[2-(5-bromo-2-methoxyphenyl)-ethyl]-3-fluoro-phenyl]-4,5-dihydro-1H -imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model  Academic Article
• Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{ (3s)-3-piperidinylmethyl oxy}-1H-imidazo 4,5-c pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase  Academic Article
• Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome  Academic Article
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• Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD8  Academic Article
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• Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen  Academic Article
• Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage  Academic Article
• Identification of Regulatory Elements That Control PPAR gamma Expression in Adipocyte Progenitors  Academic Article
• Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ  Academic Article
• Identification of SR2211: a potent synthetic ROR gamma-selective modulator  Academic Article
• Identification of Siglec ligands using a proximity labeling method  Academic Article
• Identification of a 2nd interferon-regulated murine mx-gene  Academic Article
• Identification of a b-cell differentiation factor(s) spontaneously produced by proliferating t-cells in murine lupus strains of the lpr-lpr genotype  Academic Article
• Identification of a brain theta-positive, secretory-cell from hematopoietic tissues  Academic Article
• Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice  Academic Article
• Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators  Academic Article
• Identification of a flavin mononucleotide module residue critical for activity of inducible nitrite oxide synthase  Academic Article
• Identification of a growth factor for primary murine stroma as macrophage colony-stimulating factor  Academic Article
• Identification of a new marker (LY RL-male-1) for cells of the T-lineage by an auto-antithymocyte serum  Academic Article
• Identification of a novel Mcl-1 protein binding motif  Academic Article
• Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors  Academic Article
• Identification of a novel protein kinase A anchoring protein that binds both type l and type ll regulatory subunits  Academic Article
• Identification of a novel protein regulating microtubule stability through a chemical approach  Academic Article
• Identification of a novel small molecule HIF-1-α translation inhibitor  Academic Article
• Identification of a photoreceptor-specific messenger-rna encoded by the gene responsible for retinal degeneration slow (rds)  Academic Article
• Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors  Academic Article
• Identification of a potent and selective noncovalent cathepsin S inhibitor  Academic Article
• Identification of a selective ROR gamma ligand that suppresses T(H)17 cells and stimulates T regulatory cells  Academic Article
• Identification of a small molecular insulin receptor agonist with potent antidiabetes activity  Academic Article
• Identification of a small molecule with activity against drug-resistant and persistent tuberculosis  Academic Article
• Identification of a tlr4- and trif-dependent activation program of dendritic cells  Academic Article
• Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity  Academic Article
• Identification of adenovirus serotype 5 hexon regions that interact with scavenger receptors  Academic Article
• Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism  Academic Article
• Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and lassa fever virus  Academic Article
• Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
• Identification of an EGFRvIII-JNK2-HGF/c-Met-signaling axis required for intercellular crosstalk and glioblastoma multiforme cell invasion  Academic Article
• Identification of an il-17-producing nk1.1(neg) inkt cell population involved in airway neutrophilia  Academic Article
• Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening  Academic Article
• Identification of d-b- and k-b-restricted subdominant cytotoxic t-cell responses in lymphocytic choriomeningitis virus-infected mice  Academic Article
• Identification of derepressed autoimmunocompetent B lymphoid cells in NZB mice  Academic Article
• Identification of encephalitogenic V-beta-4-bearing T-cells in SJL mice. Further evidence for the V-region disease hypothesis  Academic Article
• Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A)  Academic Article
• Identification of genes regulated in the mouse extended amygdala by excessive ethanol drinking associated with dependence  Academic Article
• Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor  Academic Article
• Identification of ligands and coligands for the ecdysone-regulated gene switch  Academic Article
• Identification of lps2 as a key transducer of myd88-independent tir signalling  Academic Article
• Identification of murine leukemia viral antigens detected on mouse cells by H-2 alloantisera  Academic Article
• Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility  Academic Article
• Identification of non-csp antigens bearing cd8 epitopes in mice immunized with irradiated sporozoites  Academic Article
• Identification of novel binding elements and gene targets for the homeodomain protein BARX2  Academic Article
• Identification of novel functional regions important for the activity of HOXB7 in mammalian cells  Academic Article
• Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis  Academic Article
• Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification  Academic Article
• Identification of novel selective V-2 receptor non-peptide agonists  Academic Article
• Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach  Academic Article
• Identification of novel transcription-regulating genes expressed during murine molar development  Academic Article
• Identification of osteopontin as a novel ligand for the integrin alpha 8 beta 1 and potential roles for this integrin-ligand interaction in kidney morphogenesis  Academic Article
• Identification of p53 regulators by genome-wide functional analysis  Academic Article
• Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor a in HepG2 cells  Academic Article
• Identification of phosphorylation codes for arrestin recruitment by G protein-coupled receptors  Academic Article
• Identification of primitive hematopoietic stem cells in mice by the limiting dilution method [Article in Russian]  Academic Article
• Identification of protective lassa virus epitopes that are restricted by hla-a2  Academic Article
• Identification of protein pheromones that promote aggressive behaviour  Academic Article
• Identification of pyrrolo[2,1-f][1,2,4] triazine-based inhibitors of Met kinase  Academic Article
• Identification of receptors for pig endogenous retrovirus  Academic Article
• Identification of retroviral gp70 and anti-gp70 antibodies involved in circulating immune-complexes in nzbxnzw mice  Academic Article
• Identification of selective inhibitors of the Plasmodium falciparum hexose transporter PfHT by screening focused libraries of anti-malarial compounds  Academic Article
• Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP  Academic Article
• Identification of small molecular weight inhibitors of Src homology 2 domain-containing tyrosine phosphatase 2 (SHP-2) via in silico database screening combined with experimental assay  Academic Article
• Identification of small molecule activators of cryptochrome  Academic Article
• Identification of small-molecule inducers of pancreatic β-cell expansion  Academic Article
• Identification of subunits of gonococcal rna-polymerase by immunoblot analysis - evidence for multiple sigma-factors  Academic Article
• Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9  Academic Article
• Identification of the antiarrhythmic drugs amiodarone and lorcainide as potent H3 histamine receptor inverse agonists  Academic Article
• Identification of the first potent, selective and bioavailable PPARα antagonist  Academic Article
• Identification of the first synthetic steroidogenic factor 1 inverse agonists: Pharmacological modulation of steroidogenic enzymes  Academic Article
• Identification of the key LMO2-binding determinants on Ldb1  Academic Article
• Identification of the low density lipoprotein (ldl) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris  Academic Article
• Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells  Academic Article
• Identification of the protein product of the c-mos proto-oncogene in mouse testes  Academic Article
• Identification of the regions involved in DNA binding by the mouse PEBP2alpha protein  Academic Article
• Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling  Academic Article
• Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties  Academic Article
• Identification of transcription factor binding sites in the human genome sequence  Academic Article
• Identification of unknown protein function using metabolite cocktail screening  Academic Article
• Identifying a small molecule blocking antigen presentation in autoimmune thyroiditis  Academic Article
• Identifying blood biomarkers for mood disorders using convergent functional genomics  Academic Article
• Identifying the long-term role of inducible nitric oxide synthase after contusive spinal cord injury using a transgenic mouse model  Academic Article
• Identity of tumor necrosis factor and the macrophage-secreted factor cachectin  Academic Article
• Idiotypic cross-reactivity of anti-gat and anti-alprenolol antibodies - an approach to the structural correlates of the pgat idiotypic specificity  Academic Article
• Idiotypy of catecholamine-binding proteins  Academic Article
• Ifit1 protects against lipopolysaccharide and D-galactosamine-induced fatal hepatitis by inhibiting activation of the JNK Pathway  Academic Article
• Ifn-gamma-inducible protein-10 is essential for the generation of a protective tumor-specific cd8 t cell response induced by single-chain il-12 gene therapy  Academic Article
• Ifn-gamma-inducing factor il-18 administration mediates ifn-gamma- and il-12-independent antitumor effects  Academic Article
• Ig heavy-chain variable region gene-complex of lupus mice exhibits normal restriction fragment length polymorphism  Academic Article
• IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions  Academic Article
• IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model  Academic Article
• IgM anti-histone H-3 antibody associated with undifferentiated rheumatic disease syndromes  Academic Article
• IgM-producing tumors in the BALB-c mouse: A model for B-cell maturation  Academic Article
• IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells  Academic Article
• Il-1-alpha and tnf-alpha differentially regulate cd4 and mac-1 expression in mouse microglia  Academic Article
• Il-10 blockade facilitates DNA vaccine-induced t cell responses and enhances clearance of persistent virus infection  Academic Article
• Il-10 directly suppresses cd4 but not cd8 t cell effector and memory responses following acute viral infection  Academic Article
• Il-21 is required to control chronic viral infection  Academic Article
• Il-5 links adaptive and natural immunity specific for epitopes of oxidized ldl and protects from atherosclerosis  Academic Article
• Il-7 and il-15 differentially regulate cd8(+) t-cell subsets during contraction of the immune response  Academic Article
• Il-7 is critical for homeostatic proliferation and survival of naive t cells  Academic Article
• Il-7 regulates basal homeostatic proliferation of antiviral cd4(+)t cell memory  Academic Article
• Il-7/anti-il-7 mab complexes restore t cell development and induce homeostatic t cell expansion without lymphopenia  Academic Article
• Ila, the human 4-1bb homolog, is inducible in lymphoid and other cell lineages  Academic Article
• Illumination of the melanopsin signaling pathway  Academic Article
• Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen  Academic Article
• Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery  Academic Article
• Imaging of tumor vascularization using fluorescence molecular tomography to monitor arginine deiminase treatment in melanoma  Academic Article
• Imaging secretory vesicles by fluorescent protein insertion in propeptide rather than mature secreted peptide  Academic Article
• Imaging tumor burden in the brain with 89-Zr-transferrin  Academic Article
• Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis  Academic Article
• Imidazolopiperazines: Hit to lead optimization of new antimalarial agents  Academic Article
• Imidazolopiperazines: Lead optimization of the second-generation antimalarial agents  Academic Article
• Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models  Academic Article
• Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form  Academic Article
• Immortalized clones of fibroblastic reticular cells activate virus-specific t cells during virus infection  Academic Article
• Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection  Academic Article
• Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes  Academic Article
• Immune complex disease in experimental animals and man  Academic Article
• Immune effectors required for hepatitis B virus clearance  Academic Article
• Immune pathogenesis of hepatocellular carcinoma  Academic Article
• Immune regulation by the st6gal sialyltransferase  Academic Article
• Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis  Academic Article
• Immune response of mice, rabbits and cattle to inactivated Mycoplasma mycoides subspecies Mycoides vaccines containing adjuvants  Academic Article
• Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization  Academic Article
• Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus  Academic Article
• Immune system-dependent and -independent replication of the scrapie agent  Academic Article
• Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10  Academic Article
• Immune tolerance split between hepatitis B virus precore and core proteins  Academic Article
• Immune versus natural selection: Antibody aldolases with enzymic rates but broader scope  Academic Article
• Immune-complexes can trigger specific, t-cell-dependent, autoanti-igg antibody-production in mice  Academic Article
• Immune-complexes in cancer - demonstration of complexes in mice bearing neuroblastomas  Academic Article
• Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice  Academic Article
• Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes  Academic Article
• Immunization of hu-pbl-scid mice and the rescue of human monoclonal fab fragments through combinatorial libraries  Academic Article
• Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity  Academic Article
• Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune responses in mice and woodchucks  Academic Article
• Immunobiology and pathogenesis of hepatocellular injury in hepatitis-B virus transgenic mice  Academic Article
• Immunobiology of Epstein-Barr virus-associated lymphomas  Academic Article
• Immunobiology of the autoantibody response. I. Circulating analogues of erythrocyte autoantigens and heterogeneity of the autoimmune response of NZB mice  Academic Article
• Immunobiology of the autoantibody response. II. The lipoprotein-associated soluble HB erythrocyte autoantigen of NZB mice  Academic Article
• Immunochemical characterization of human-tumor antigens  Academic Article
• Immunochemical heterogeneity of human-plasma high-density lipoproteins - identification with apolipoprotein a-i-specific and a-ii-specific monoclonal-antibodies  Academic Article
• Immunochemical termination of self-tolerance  Academic Article
• Immunochemistry of the dominating antigenic region ala582 to cys604 in the transmembranous protein of simian and human immunodeficiency virus  Academic Article
• Immunocytochemical demonstration of neural cell-adhesion molecule (ncam) along the migration route of luteinizing-hormone-releasing hormone (lhrh) neurons in mice  Academic Article
• Immunocytokines: A new approach to immunotherapy of melanoma  Academic Article
• Immunocytokines: A promising approach to cancer immunotherapy  Academic Article
• Immunodeficient mice xenografted with human lymphoid cells: new models for in vivo studies of human immunobiology and infectious diseases  Academic Article
• Immunodetection of cell-bound antigens using both mouse and human monoclonal-antibodies  Academic Article
• Immunodominance in virus-induced cd8(+) t-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon  Academic Article
• Immunoelectronmicroscopy of neural antigens on ultrathin frozen-sections  Academic Article
• Immunogenic peptides corresponding to the dominant antigenic region alanine-597 to cysteine-619 in the transmembrane protein of simian immunodeficiency virus have a propensity to fold in aqueous solution  Academic Article
• Immunogenic stability of heat-killed Mycoplasma mycoides subsp. Mycoides at 4 degrees C  Academic Article
• Immunogenicity and partial-purification of soluble h-2 antigens extracted with hypertonic salt  Academic Article
• Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: Implications for immunotherapy of persistent viral infections  Academic Article
• Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: Identification of an H2-Kd-restricted CTL epitope  Academic Article
• Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines  Academic Article
• Immunoglobulin gene rearrangement in b-cell deficient mice generated by targeted deletion of the j(h) locus  Academic Article
• Immunoglobulin-g - functional sites  Academic Article
• Immunoglobulin-kappa light chain variable region gene-complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice  Academic Article
• Immunoglobulins can utilize riboflavin (vitamin b2) to activate the antibody-catalyzed water oxidation pathway  Academic Article
• Immunohistochemical analysis of the development of somatostatin in the reeler neocortex  Academic Article
• Immunologic and biochemical properties of the histamine-sensitizing factor from Bordetella pertussis  Academic Article
• Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris  Academic Article
• Immunologic effects of an orally available BRAFV600E inhibitor in BRAF wild-type murine models  Academic Article
• Immunological and pathological consequences of coxsackievirus RNA persistence in the heart  Academic Article
• Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies  Academic Article
• Immunological basis of resistance to RL-male-1 induced by immunoselected Thy-1.2 negative variants  Academic Article
• Immunological detection of thymidine photoproduct formation in vivo  Academic Article
• Immunological disease induced by injecting F1 lymphoid cells into certain parental strains  Academic Article
• Immunological effects of neonatal infection with mouse thymic virus  Academic Article
• Immunological functions of lymphocytes fractionated with antigen-derivatized fibers  Academic Article
• Immunological relation of basement membrane and a serum beta globulin in the mouse. Demonstration of renal basement membrane alteration in mice injected with streptolysin S  Academic Article
• Immunological tumor destruction in a murine melanoma model by targeted lt alpha independent of secondary lymphoid tissue  Academic Article
• Immunology of muscarinic acetylcholine and beta-adrenergic catecholamine receptors  Academic Article
• Immunology: Toll-like receptors and antibody responses  Academic Article
• Immunomodulation and the quorum sensing molecule 3-oxo-C-12-homoserine lactone: The importance of chemical scaffolding for probe development  Academic Article
• Immunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation  Academic Article
• Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling  Academic Article
• Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (balb-c times nzb)f1 mice by scripps leukemia virus  Academic Article
• Immunopathology and pathogenesis of cutaneous involvement in systemic lupus erythematosus  Academic Article
• Immunopathology of adoptive immunization in mice chronically infected with lymphocytic choriomeningitis virus  Academic Article
• Immunopharmacotherapeutic manifolds and modulation of cocaine overdose  Academic Article
• Immunoproteasome-deficient mice mount largely normal cd8(+) t cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination  Academic Article
• Immunoselection of structural H-2Kb variants: use of cloned cytolytic T cells to select for loss of a CTL-defined allodeterminant  Academic Article
• Immunostimulatory DNA sequences necessary for effective intradermal gene immunization  Academic Article
• Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase  Academic Article
• Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells  Academic Article
• Immunosuppressive and autoimmune effects of thimerosal in mice  Academic Article
• Immunosuppressive effects of 3-methylcholanthrene given intratracheally in various inbred strains of mice  Academic Article
• Immunosuppressive effects of glucosamine  Academic Article
• Immunosuppressive effects of subglutinol derivatives  Academic Article
• Immunosurveillance of the liver by intravascular effector CD8(+) T cells  Academic Article
• Immunotherapy for virus-infection  Academic Article
• Immunotherapy of a murine colon cancer with syngeneic spleen-cells, immune rna and tumor-antigen  Academic Article
• Immunotherapy with a posttranscriptionally modified DNA vaccine induces complete protection against metastatic neuroblastoma  Academic Article
• Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells  Academic Article
• Impact of C4'-O-alkyl linker on in vivo pharmacokinetics of near-infrared cyanine/monoclonal antibody conjugates  Academic Article
• Impact of distinct chemical structures for the development of a methamphetamine vaccine  Academic Article
• Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice  Academic Article
• Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function  Academic Article
• Impact of sleep and circadian disruption on energy balance and diabetes: a summary of workshop discussions  Academic Article
• Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself  Academic Article
• Impact of substituents in tumor uptake and fluorescence imaging ability of near-infrared cyanine-like dyes  Academic Article
• Impact of sugar stereochemistry on natural killer T cell stimulation by bacterial glycolipids  Academic Article
• Impact of β2 integrin deficiency on mouse natural killer cell development and function  Academic Article
• Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein  Academic Article
• Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice  Academic Article
• Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome  Academic Article
• Impaired immunoproteasome assembly and immune responses in pa28(-/-) mice  Academic Article
• Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice  Academic Article
• Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain  Academic Article
• Impaired lymphopoiesis and altered b cell subpopulations in mice overexpressing lnk adaptor protein  Academic Article
• Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system  Academic Article
• Impaired microrna processing causes corpus luteum insufficiency and infertility in mice  Academic Article
• Impaired negative regulation of homeostatically proliferating T cells  Academic Article
• Impaired prion replication in spleens of mice lacking functional follicular dendritic cells  Academic Article
• Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin  Academic Article
• Impaired water maze learning performance in mu-opioid receptor knockout mice  Academic Article
• Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis  Academic Article
• Impairment of dopaminergic system function after chronic treatment with corticotropin-releasing factor  Academic Article
• Impairment of spatial but not contextual memory in camkii mutant mice with a selective loss of hippocampal ltp in the range of the theta-frequency  Academic Article
• Importance of cellular microenvironment and circulatory dynamics in b cell immunotherapy  Academic Article
• Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection  Academic Article
• Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers  Academic Article
• Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant  Academic Article
• Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist  Academic Article
• In a transgenic model of spontaneous autoimmune diabetes, expression of a protective class II MHC molecule results in thymic deletion of diabetogenic CD8+ T cells  Academic Article
• In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages  Academic Article
• In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness  Academic Article
• In silico qtl mapping of basal liver iron levels in inbred mouse strains  Academic Article
• In situ click chemistry: Enzyme inhibitors made to their own specifications  Academic Article
• In situ cytokine therapy: Redistribution of clonally expanded t cells  Academic Article
• In situ measurement of solute transport in the bone lacunar-canalicular system  Academic Article
• In situ selection of lead compounds by click chemistry: Target-guided optimization of acetylcholinesterase inhibitors  Academic Article
• In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics  Academic Article
• In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the alpha 6 beta 4 integrin and dystroglycan  Academic Article
• In vitro and in vivo anticancer activity of a synthetic glycolipid as Toll-like receptor 4 (TLR4) activator  Academic Article
• In vitro and in vivo neurotoxicity of prion protein oligomers  Academic Article
• In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi  Academic Article
• In vitro construction of a b-tropic virus by recombination - b-tropism is a cryptic phenotype of xenotropic murine retroviruses  Academic Article
• In vitro dendritic cell infection by pseudotyped adenoviral vectors does not correlate with their in vivo immunogenicity  Academic Article
• In vitro detection of cells infected with lactic dehydrogenase virus (LDV) by fluorescein-labeled antibody to LDV  Academic Article
• In vitro drug testing using hemopoietic cells: goals and limitations  Academic Article
• In vitro functional-characterization of sag-3 - a naturally-occurring monoclonal-antibody in nzb mice - specificity toward functional t-cell subsets  Academic Article
• In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots  Academic Article
• In vitro responses of CBA/N mice: spleen cells of mice with an X-linked defect that precludes immune responses to several thymus-independent antigens can respond to TNP-lipopolysaccharide  Academic Article
• In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library  Academic Article
• In vitro studies of the genetically determined unresponsiveness to thymus-independent antigens in CBA/N mice  Academic Article
• In vitro transformation of murine bone marrow cells with a v-raf/v-myc retrovirus yields clonally related mature b cells and macrophages  Academic Article
• In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses  Academic Article
• In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation  Academic Article
• In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire  Academic Article
• In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease  Academic Article
• In vivo accumulation of t cells in response to il-2/anti-il-2 mab complexes is dependent in part on the tnf family ligand 4-1bbl  Academic Article
• In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, mk-826 (l-749,345)  Academic Article
• In vivo activity in a catalytic antibody-prodrug system: antibody catalyzed etoposide prodrug activation for selective chemotherapy  Academic Article
• In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance  Academic Article
• In vivo and in vitro production of anti-histone antibodies in NZB/NZW mice  Academic Article
• In vivo and in vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker  Academic Article
• In vivo anergized T cells form altered immunological synapses in vitro  Academic Article
• In vivo brain GPCR signaling elucidated by phosphoproteomics  Academic Article
• In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons  Academic Article
• In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects  Academic Article
• In vivo cleavage of alpha 2,6-sialyltransferase by alzheimer beta-secretase  Academic Article
• In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated beta1 integrin and induction of FAK/PI3K/Akt motility signaling  Academic Article
• In vivo complementation of complex i by the yeast ndi1 enzyme - possible application for treatment of parkinson disease  Academic Article
• In vivo conversion of bm plasmacytoid dc into cd11b(+) conventional dc during virus infection  Academic Article
• In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides  Academic Article
• In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I  Academic Article
• In vivo efficacy of natural product-inspired irreversible kinase inhibitors  Academic Article
• In vivo efficacy of novel synthetic enediynes 1  Academic Article
• In vivo expansion of t reg cells with il-2-mab complexes: Induction of resistance to eae and long-term acceptance of islet allografts without immunosuppression  Academic Article
• In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes  Academic Article
• In vivo expression of human growth hormone by genetically modified murine bone marrow stromal cells and its effect on the cells in vitro  Academic Article
• In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection  Academic Article
• In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers  Academic Article
• In vivo imaging of hepcidin promoter stimulation by iron and inflammation  Academic Article
• In vivo interrogation of the molecular display of atherosclerotic lesion surfaces  Academic Article
• In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function  Academic Article
• In vivo osteopontin-induced macrophage accumulation is dependent on CD44 expression  Academic Article
• In vivo potent BM635 analogue with improved drug-like properties  Academic Article
• In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models  Academic Article
• In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation  Academic Article
• In vivo regulation of crkii and crkl proto-oncogenes in the uterus by insulin-like growth factor-i - differential effects on tyrosine phosphorylation and association with paxillin  Academic Article
• In vivo regulation of hepatitis B virus replication by peroxisome proliferators  Academic Article
• In vivo relevance for platelet glycoprotein Ib alpha residue Tyr276 in thrombus formation  Academic Article
• In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice  Academic Article
• In vivo selection for metastasis promoting genes in the mouse  Academic Article
• In vivo stabilization of mutant human transthyretin in transgenic mice  Academic Article
• In vivo suppression of the primary immune response by a species of low density serum lipoprotein  Academic Article
• In vivo targeting of b-cell lymphoma with glycan ligands of cd22  Academic Article
• In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors  Academic Article
• In vivo treatment with a mhc class i-restricted blocking peptide can prevent virus-induced autoimmune diabetes  Academic Article
• In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line  Academic Article
• In vivo-activated cd4 t cells upregulate cxc chemokine receptor 5 and reprogram their response to lymphoid chemokines  Academic Article
• In-frame TCR delta-gene rearrangements play a critical role in the alpha-beta/gamma-delta T-cell lineage decision  Academic Article
• Inability of il-2 and il-10 to counteract b-cell clonal deletion  Academic Article
• Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers  Academic Article
• Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging  Academic Article
• Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids  Academic Article
• Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1  Academic Article
• Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1  Academic Article
• Inactivation of macrophage nitric oxide synthase activity by ng-methyl-l-arginine  Academic Article
• Inactivation of pkc theta leads to increased susceptibility to obesity and dietary insulin resistance in mice  Academic Article
• Inactivation of the 5-ht7 receptor partially blocks phencyclidine-induced disruption of prepulse inhibition  Academic Article
• Inactivation of the p53 pathway in retinoblastoma  Academic Article
• Inactivation of thiol-dependent enzymes by hypothiocyanous acid: Role of sulfenyl thiocyanate and sulfenic acid intermediates  Academic Article
• Incomplete T-cell receptor V-beta allelic exclusion and dual V-beta-expressing cells  Academic Article
• Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: Generation of antibodies against the thrombin-sensitive region of murine protein S  Academic Article
• Incorporation of phosphonate into benzonaphthyridine toll-like receptor 7 agonists for adsorption to aluminum hydroxide  Academic Article
• Incorporation of the purified epstein-barr virus/c3d receptor (cr-2) into liposomes and demonstration of its dual ligand-binding functions  Academic Article
• Increase of anti-metastatic efficacy by selectivity-but not affinity-optimization of synthetic serine protease inhibitors  Academic Article
• Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal  Academic Article
• Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A  Academic Article
• Increased c-fos expression in the central nucleus of the amygdala and enhancement of cued fear memory in dyt1 delta gag knock-in mice  Academic Article
• Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)  Academic Article
• Increased endothelial expression of toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events  Academic Article
• Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice  Academic Article
• Increased ethanol self-administration in delta-opioid receptor knockout mice  Academic Article
• Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies  Academic Article
• Increased expression of fibronectin and the alpha 5 beta 1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia  Academic Article
• Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction  Academic Article
• Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "klotho" mouse  Academic Article
• Increased expression of the beta 4 and alpha 5 integrin subunits in cerebral blood vessels of transgenic mice chronically producing the pro-inflammatory cytokines il-6 or ifn-alpha, in the central nervous system  Academic Article
• Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice  Academic Article
• Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance  Academic Article
• Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice  Academic Article
• Increased immune response variability during simultaneous viral coinfection leads to unpredictability in CD8 T cell immunity and pathogenesis  Academic Article
• Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta(-/-) mice  Academic Article
• Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7α-hydroxylase  Academic Article
• Increased response to morphine in mice lacking protein kinase c epsilon  Academic Article
• Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase  Academic Article
• Increased spectrin proteolysis in the brindled mouse-brain  Academic Article
• Increased survival and reduced neutrophil infiltration of the liver in Rab27a-but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation  Academic Article
• Increased survival times of new-zealand hybrid mice immunosuppressed by graft versus host reactions  Academic Article
• Increased susceptibility to DNA virus infection in mice with a GCN2 mutation  Academic Article
• Increased thrombogenesis and embolus formation in mice lacking glycoprotein V  Academic Article
• Increased yield of antibody-producing murine spleen-cell hybridomas from fusions cultured in medium supplemented with mouse serum  Academic Article
• Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation  Academic Article
• Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia  Academic Article
• Increasing t-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex - mismatched bone marrow transplant model  Academic Article
• Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality  Academic Article
• Increasing the chemical potential of the germ-line antibody repertoire  Academic Article
• Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of EphB2 and neuronal activity  Academic Article
• Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization  Academic Article
• Individual V-H promoters vary in strength, but the frequency of rearrangement of those V-H genes does not correlate with promoter strength nor enhancer-independence  Academic Article
• Individually programmable cell stretching microwell arrays actuated by a Braille display  Academic Article
• Indoleamine 2,3-dioxygenase expression in trans-planted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes  Academic Article
• Induced pluripotent stem cells free of exogenous reprogramming factors  Academic Article
• Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses  Academic Article
• Inducible and reversible gene expression with the rtta system for the study of memory  Academic Article
• Inducible control of gene expression with destabilized Cre  Academic Article
• Inducible expression of the long pentraxin PTX3 in the central nervous system  Academic Article
• Inducible gene expression in mammalian cells and transgenic mice  Academic Article
• Inducible nitric oxide synthase: Role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction  Academic Article
• Induction and rapid expression of an immune response in vitro  Academic Article
• Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules  Academic Article
• Induction of B cell priming by neonatal injection of mice with thymic-independent (type 2) antigens  Academic Article
• Induction of B lymphocyte proliferation by monoclonal anti-Lyb 2 antibody  Academic Article
• Induction of CD44 expression by the Epstein-Barr virus latent membrane protein LMP1 is associated with lymphoma dissemination  Academic Article
• Induction of a pharmacologically active clonotypic b-cell response directed to an immunogenic region of the human beta-2-adrenergic receptor  Academic Article
• Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins  Academic Article
• Induction of an antibody that catalyzes the hydrolysis of an amide bond  Academic Article
• Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12  Academic Article
• Induction of antiviral antibodies by DNA immunization requires neither perforin-mediated nor cd8(+)-t-cell-mediated lysis of antigen-expressing cells  Academic Article
• Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded microRNA-15a  Academic Article
• Induction of c-fos mRNA in the arcuate nucleus of normal and mutant growth hormone-deficient mice by a synthetic non-peptidyl growth hormone secretagogue  Academic Article
• Induction of c-fos messenger-rna and ap-1 DNA-binding activity by camp in cooperation with either the adenovirus 243-amino or the adenovirus 289-amino acid e1a protein  Academic Article
• Induction of hematopoietic microenvironment by the extracellular matrix from long-term bone marrow cultures  Academic Article
• Induction of high serum levels of retroviral env gene-products (gp70) in mice by bacterial lipopolysaccharide  Academic Article
• Induction of igg antibodies by an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
• Induction of interferon-gamma inducing factor in the adrenal cortex  Academic Article
• Induction of minor alloantigen-specific T cell subsets in vivo: recognition of processed antigen by helper but not by cytotoxic T cell precursors  Academic Article
• Induction of monocyte procoagulant activity by murine hepatitis-virus type-3 parallels disease susceptibility in mice  Academic Article
• Induction of murine autoimmune-disease by chronic polyclonal b-cell activation  Academic Article
• Induction of nitrite/nitrate synthesis in murine macrophages by bcg infection, lymphokines, or interferon-gamma  Academic Article
• Induction of ornithine decarboxylase by il-3 is mediated by sequential c-myc-independent and c-myc-dependent pathways  Academic Article
• Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3  Academic Article
• Induction of persistent tumor-protective immunity in mice cured of established colon carcinoma metastases  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in adipocytes by thiazolidinediones  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha  Academic Article
• Induction of pluripotency in mouse somatic cells with lineage specifiers  Academic Article
• Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds  Academic Article
• Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2  Academic Article
• Induction of pregnancy during established EAE halts progression of CNS autoimmune injury via pregnancy-specific serum factors  Academic Article
• Induction of retinal progenitors and neurons from mammalian Müller glia under defined conditions  Academic Article
• Induction of rheumatoid antibodies in the mouse - regulated production of autoantibody in the secondary humoral response  Academic Article
• Induction of severe autoimmune-disease in normal mice by simultaneous action of multiple immunostimulators  Academic Article
• Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice  Academic Article
• Induction of systemic autoimmunity by a xenobiotic requires endosomal TLR trafficking and signaling from the late endosome and endolysosome but not type I IFN  Academic Article
• Induction of the early growth response (Egr) family of transcription factors during thymic selection  Academic Article
• Induction of transcription factor ap-1 by adenovirus e1a-protein and camp  Academic Article
• Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice  Academic Article
• Induction of type-i interferon genes and interferon-inducible genes in embryonal stem-cells devoid of interferon regulatory factor-i  Academic Article
• Infected cd8 alpha(-) dendritic cells are the predominant source of il-10 during establishment of persistent viral infection  Academic Article
• Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice  Academic Article
• Infection control by antibody disruption of bacterial quorum sensing signaling  Academic Article
• Infection of lymphocytes by a virus that aborts cytotoxic lymphocyte-t activity and establishes persistent infection  Academic Article
• Infection with a recombinant vaccinia virus encoding myelin proteolipid protein causes suppression of chronic relapsing-remitting experimental allergic encephalomyelitis  Academic Article
• Infection with vaccinia favors the selection of hybridomas synthesizing autoantibodies against intermediate filaments, one of them cross-reacting with the virus hemagglutinin  Academic Article
• Infectious rna isolated from the spinal cords of mice chronically infected with theiler's murine encephalomyelitis virus  Academic Article
• Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA  Academic Article
• Infectivity of scrapie prions bound to a stainless steel surface  Academic Article
• Inflammasome activation by cystine crystals: implications for the pathogenesis of cystinosis  Academic Article
• Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity  Academic Article
• Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger  Academic Article
• Inflammation in atherosclerosis - lesion formation in ldl receptor-deficient mice with perforin and lyst(beige) mutations  Academic Article
• Inflammation, obesity, and thrombosis  Academic Article
• Inflammatory cells in solid murine neoplasms. I. Tumor disaggregation and identification of constituent inflammatory cells  Academic Article
• Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression  Academic Article
• Inflammatory cytokines: Putative regulators of neuronal and neuro-endocrine function  Academic Article
• Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice  Academic Article
• Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer  Academic Article
• Influence of antigen on a model for analysis of multiple coordinate events associated with the primary immune-response  Academic Article
• Influence of coding-end sequence on coding-end processing in V(D)J recombination  Academic Article
• Influence of the N-terminal domain on the aggregation properties of the prion protein  Academic Article
• Influence of the immunoregulatory serum lipoprotein LDL-In on the in vivo proliferation and differentiation of antigen-binding and antibody-secreting lymphocytes during a primary immune response  Academic Article
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• Inhibition by mk-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice  Academic Article
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• Inhibition of baclofen on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity  Academic Article
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• Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4  Academic Article
• Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task  Academic Article
• Inhibition of hepatitis B virus in mice by RNA interference  Academic Article
• Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice  Academic Article
• Inhibition of hepatitis B virus replication during schistosoma mansoni infection in transgenic mice  Academic Article
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• Inhibition of immunological injury of cultured-cells infected with lymphocytic choriomeningitis virus - role of defective interfering virus in regulating viral antigenic expression  Academic Article
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• Inhibition of lipopolysaccharide activation of 70z/3 cells by anti-lipopolysaccharide antibodies  Academic Article
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• Inhibition of matrix metalloproteinase 9 activation by a specific monoclonal antibody  Academic Article
• Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway  Academic Article
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• Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance  Academic Article
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• Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate  Academic Article
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• Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice  Academic Article
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• Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling  Academic Article
• Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome  Academic Article
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• Inositol pyrophosphates pyrotechnics  Academic Article
• Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling  Academic Article
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• Instant immunity through chemically programmable vaccination and covalent self-assembly  Academic Article
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• Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2  Academic Article
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• Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors  Academic Article
• Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells  Academic Article
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• Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes  Academic Article
• Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice  Academic Article
• Integrated regulation of toll-like receptor responses by notch and interferon-gamma pathways  Academic Article
• Integration of cardiac proteome biology and medicine by a specialized knowledgebase  Academic Article
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• Integrative analysis of low- and high-resolution eqtl  Academic Article
• Integrative assessment of chlorine-induced acute lung injury in mice  Academic Article
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• Interactions between viruses and lymphocytes. I. In vivo replication of lymphocytic choriomeningitis virus in mononuclear cells during both chronic and acute viral infections  Academic Article
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• Interferon modulation of cellular microRNAs as an antiviral mechanism  Academic Article
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• Knock-down of the 37-kda/67-kda laminin receptor in mouse brain by transgenic expression of specific antisense lrp rna  Academic Article
• Knock-in mice reveal nonsense-mediated mRNA decay in the brain  Academic Article
• Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool  Academic Article
• Knock-in of α3 connexin prevents severe cataracts caused by an α8 point mutation  Academic Article
• Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy  Academic Article
• Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes  Academic Article
• Ksa antigen ep-cam mediates cell-cell adhesion of pancreatic epithelial cells: Morphoregulatory roles in pancreatic islet development  Academic Article
• Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination  Academic Article
• Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis  Academic Article
• Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature  Academic Article
• L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity  Academic Article
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• Limiting the available t-cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology  Academic Article
• Limits of a deletion spanning Tlr4 in C57BL/10ScCr mice  Academic Article
• Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro  Academic Article
• Linear padre t helper epitope and carbohydrate b cell epitope conjugates induce specific high titer igg antibody responses  Academic Article
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• Lipid binding promotes oligomerization and focal adhesion activity of vinculin  Academic Article
• Lipid tucaresol as an adjuvant for methamphetamine vaccine development  Academic Article
• Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors  Academic Article
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• Lipoproteins inhibit macrophage activation by lipoteichoic acid  Academic Article
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• Localization at high-resolution of antibody-induced mobilization of vaccinia virus hemagglutinin and the major histocompatibility antigens on the plasma-membrane of infected-cells  Academic Article
• Localization of 2 epitopes of apolipoprotein-a-i that are exposed on human high-density lipoproteins using monoclonal-antibodies and synthetic peptides  Academic Article
• Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as neural signaling molecules  Academic Article
• Localization of a passively transferred human recombinant monoclonal antibody to herpes simplex virus glycoprotein D to infected nerve fibers and sensory neurons in vivo  Academic Article
• Localization of a stable neural correlate of associative memory  Academic Article
• Localization of an apolipoprotein-a-i epitope critical for activation of lecithin-cholesterol acyltransferase  Academic Article
• Localization of an apolipoprotein-a-i epitope critical for lipoprotein-mediated cholesterol efflux from monocytic cells  Academic Article
• Localization of cholesterol, amyloid and glia in alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (tof-sims) and immunofluorescence imaging  Academic Article
• Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression  Academic Article
• Localization of sarcomeric proteins during myofibril assembly in cultured mouse primary skeletal myotubes  Academic Article
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• Localization of the human jun protooncogene to chromosome region 1p31-32  Academic Article
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