subject area of

• "Viral deja vu" elicits organ-specific immune disease independent of reactivity to self  Academic Article
• 'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast  Academic Article
• (18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils  Academic Article
• -Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity  Academic Article
• 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation  Academic Article
• 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
• 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females  Academic Article
• 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination  Academic Article
• 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles  Academic Article
• 2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors  Academic Article
• 2-Aminobenzimidazoles as potent Aurora kinase inhibitors  Academic Article
• 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases  Academic Article
• 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of beta-amyloid aggregation  Academic Article
• 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution  Academic Article
• 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 2  Academic Article
• 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth  Academic Article
• 4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase  Academic Article
• 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency  Academic Article
• 5,​6-methanoleukotriene A(4): a potent specific inhibitor for 5-​lipoxygenase  Academic Article
• 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia  Academic Article
• 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission  Academic Article
• 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern  Academic Article
• 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent  Academic Article
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)  Academic Article
• 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2  Academic Article
• 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience  Academic Article
• 8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents  Academic Article
• 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors  Academic Article
• A 1,064 bp fragment from the promoter region of the Col11a2 gene drives LacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos  Academic Article
• A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
• A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus  Academic Article
• A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia  Academic Article
• A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity  Academic Article
• A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines  Academic Article
• A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells  Academic Article
• A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response  Academic Article
• A CreER mouse to study melanin concentrating hormone signaling in the developing brain  Academic Article
• A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth  Academic Article
• A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence  Academic Article
• A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication  Academic Article
• A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the nkg2d receptor  Academic Article
• A FAAH-regulated class of N-acyl taurines that activates TRP ion channels  Academic Article
• A Gja8 (Cx50) point mutation causes an alteration of α3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice  Academic Article
• A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection  Academic Article
• A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids  Academic Article
• A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells  Academic Article
• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis  Academic Article
• A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate  Academic Article
• A Protective Strategy against Hyperinflammatory Responses Requiring the Nontranscriptional Actions of GPS2  Academic Article
• A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum  Academic Article
• A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice  Academic Article
• A T cell receptor-specific blockade of positive selection  Academic Article
• A THEMIS:SHP1 complex promotes T-cell survival  Academic Article
• A TRP channel that senses cold stimuli and menthol  Academic Article
• A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction  Academic Article
• A binding site for homeodomain and pax proteins is necessary for l1 cell adhesion molecule gene expression by pax-6 and bone morphogenetic proteins  Academic Article
• A binding site for pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord  Academic Article
• A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy  Academic Article
• A brain detoxifying enzyme for organophosphorus nerve poisons  Academic Article
• A candidate circuit approach to investigating autism  Academic Article
• A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation  Academic Article
• A catechol-O-methyltransferase that is essential for auditory function in mice and humans  Academic Article
• A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1)  Academic Article
• A cell-autonomous requirement for the cell cycle regulatory protein, rb, in neuronal migration  Academic Article
• A cellular gene encodes scrapie prp 27-30 protein  Academic Article
• A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis  Academic Article
• A ceramide-1-phosphate analogue, pcera-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages  Academic Article
• A change in the conformation of prions accompanies the emergence of a new prion strain  Academic Article
• A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins  Academic Article
• A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor  Academic Article
• A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor  Academic Article
• A chemically induced vaccine strategy for prostate cancer  Academic Article
• A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase  Academic Article
• A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses  Academic Article
• A chimeric mouse model of Gaucher disease  Academic Article
• A combinatorial system for cloning and expressing the catalytic antibody repertoire in escherichia-coli  Academic Article
• A common and unstable copy number variant is associated with differences in glo1 expression and anxiety-like behavior  Academic Article
• A common antiviral cytotoxic lymphocyte-t epitope for diverse major histocompatibility complex haplotypes - implications for vaccination  Academic Article
• A common solution to group 2 influenza virus neutralization  Academic Article
• A comparative analysis of the immunological evolution of antibody 28B4  Academic Article
• A comparative encyclopedia of DNA elements in the mouse genome  Academic Article
• A comparison of 129S2/SvHsd and C57BL/6JO1aHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically modified mice  Academic Article
• A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis  Academic Article
• A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models  Academic Article
• A comparison of t cell memory against the same antigen induced by virus versus intracellular bacteria  Academic Article
• A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis  Academic Article
• A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol  Academic Article
• A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells  Academic Article
• A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform  Academic Article
• A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses  Academic Article
• A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles  Academic Article
• A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase  Academic Article
• A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions  Academic Article
• A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function  Academic Article
• A cost-effective fluorescence mini-microscope for biomedical applications  Academic Article
• A critical evaluation of a nicotine vaccine within a self-administration behavioral model  Academic Article
• A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection  Academic Article
• A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
• A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling  Academic Article
• A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy  Academic Article
• A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response  Academic Article
• A curly-tail modifier locus, mct1, on mouse chromosome-17  Academic Article
• A customized self-assembling peptide hydrogel for dental pulp tissue engineering  Academic Article
• A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally  Academic Article
• A designer AAV variant permits efficient retrograde access to projection neurons  Academic Article
• A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle  Academic Article
• A direct GABAergic output from the basal ganglia to frontal cortex  Academic Article
• A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification  Academic Article
• A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d  Academic Article
• A distribution-free test for tumor-growth curve analyses with application to an animal tumor-immunotherapy experiment  Academic Article
• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use  Academic Article
• A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes  Academic Article
• A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis  Academic Article
• A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli  Academic Article
• A dual-function DNA vaccine encoding carcinoembryonic antigen and cd40 ligand trimer induces t cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice  Academic Article
• A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis  Academic Article
• A dynamic search process underlies microRNA targeting  Academic Article
• A dystroglycan mutation associated with limb-girdle muscular dystrophy  Academic Article
• A factor IX-deficient mouse model for hemophilia B gene therapy  Academic Article
• A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol)  Academic Article
• A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange  Academic Article
• A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition  Academic Article
• A fluorescent plate reader assay for ceramide kinase  Academic Article
• A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome  Academic Article
• A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity  Academic Article
• A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function  Academic Article
• A fragment of human TrpRS as a potent antagonist of ocular angiogenesis  Academic Article
• A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells  Academic Article
• A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen  Academic Article
• A functional genomics strategy reveals Rora as a component of the mammalian circadian clock  Academic Article
• A functional hot spot for antigen recognition in a superagonist TCR/MHC complex  Academic Article
• A functional interaction between RIP140 and PGC-1 alpha regulates the expression of the lipid droplet protein CIDEA  Academic Article
• A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding  Academic Article
• A gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesity  Academic Article
• A gene atlas of the mouse and human protein-encoding transcriptomes  Academic Article
• A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells  Academic Article
• A genetic analysis of lupus  Academic Article
• A genetic approach to the generation of antibodies with enhanced catalytic activities  Academic Article
• A genetic determinant of the striatal dopamine response to alcohol in men  Academic Article
• A genetic determinant that specifically regulates the frequency of hematopoietic stem cells  Academic Article
• A genetic marker in the variable region of light chains of mouse immunoglobulins  Academic Article
• A genetic-locus regulates the expression of tissue-specific messenger-rnas from multiple transcription units  Academic Article
• A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing  Academic Article
• A genetically humanized mouse model for hepatitis C virus infection  Academic Article
• A genomic screen for activators of the antioxidant response element  Academic Article
• A genomic screen identifies TYRO3 as a MITF regulator in melanoma  Academic Article
• A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse  Academic Article
• A global map of lipid-binding proteins and their ligandability in cells  Academic Article
• A glycoengineered enzyme with multiple mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes  Academic Article
• A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival  Academic Article
• A heat-modifiable outer-membrane protein carries an antigen specific for the species Yersinia-enterocolitica and Yersinia-pseudotuberculosis  Academic Article
• A heat-sensitive TRP channel expressed in keratinocytes  Academic Article
• A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain  Academic Article
• A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis  Academic Article
• A highly conserved neutralizing epitope on group 2 influenza a viruses  Academic Article
• A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia  Academic Article
• A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature  Academic Article
• A hormone-dependent module regulating energy balance  Academic Article
• A human aminoacyl-tRNA synthetase as a regulator of angiogenesis  Academic Article
• A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo  Academic Article
• A human recombinant monoclonal antibody to cocaine: preparation, characterization and behavioral studies  Academic Article
• A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol  Academic Article
• A human-brain glycoprotein related to the mouse-cell adhesion molecule l1  Academic Article
• A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy  Academic Article
• A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus  Academic Article
• A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen  Academic Article
• A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters  Academic Article
• A keratinocyte-responsive gamma delta tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis  Academic Article
• A key role for lipoic acid synthesis during Plasmodium liver stage development  Academic Article
• A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues  Academic Article
• A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna  Academic Article
• A large noncoding rna is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas  Academic Article
• A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells  Academic Article
• A legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis  Academic Article
• A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status  Academic Article
• A leukocyte homologue of the il-8 receptor cxcr-2 mediates the accumulation of macrophages in atherosclerotic lesions of ldl receptor-deficient mice  Academic Article
• A liver-selective LXR inverse agonist that suppresses hepatic steatosis  Academic Article
• A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses  Academic Article
• A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGf/TNF receptor family  Academic Article
• A major conformational change in p97 aaa atpase upon atp binding  Academic Article
• A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells  Academic Article
• A metabolomics strategy for detecting protein-metabolite interactions to identify natural nuclear receptor ligands  Academic Article
• A method for rapid mouse siderocyte enrichment  Academic Article
• A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting  Academic Article
• A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids  Academic Article
• A minimally lipidated form of cell-derived apolipoprotein e exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins  Academic Article
• A minor catalytic activity of src family kinases is sufficient for maximal activation of mast cells via the high-affinity ige receptor  Academic Article
• A mitochondrial targeting two-channel responsive fluorescence probe for imaging the superoxide radical anion in vitro and in vivo  Academic Article
• A model for familial exudative vitreoretinopathy caused by LPR5 mutations  Academic Article
• A model of measles virus-induced immunosuppression: Enhanced susceptibility of neonatal human pbls  Academic Article
• A model of the cell-autonomous mammalian circadian clock  Academic Article
• A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells  Academic Article
• A molecular link between the active component of marijuana and Alzheimer's disease pathology  Academic Article
• A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3  Academic Article
• A molecular switch controls interspecies prion disease transmission in mice  Academic Article
• A monoclonal-antibody directed against the beta-1-adrenergic receptor from turkey erythrocyte-membranes  Academic Article
• A monoclonal-antibody specific for conidia and mycelium wall layer of penicillium and aspergillus  Academic Article
• A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration  Academic Article
• A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons  Academic Article
• A mouse model for nonsyndromic deafness (dfnb12) links hearing loss to defects in tip links of mechanosensory hair cells  Academic Article
• A mouse model of accelerated liver aging caused by a defect in DNA repair  Academic Article
• A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice  Academic Article
• A multifunctional bispecific antibody protects against Pseudomonas aeruginosa  Academic Article
• A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen  Academic Article
• A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans  Academic Article
• A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response  Academic Article
• A murine t-cell receptor gene-complex - isolation, structure and rearrangement  Academic Article
• A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen  Academic Article
• A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα  Academic Article
• A near-IR uncaging strategy based on cyanine photochemistry  Academic Article
• A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain  Academic Article
• A new approach to high-sensitivity differential hybridization  Academic Article
• A new method of embryonic culture for assessing global changes in brain organization  Academic Article
• A new murine CD4+ T cell subset with an unrestricted cytokine profile  Academic Article
• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis  Academic Article
• A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity  Academic Article
• A nonapoptotic role for BAX and BAK in eicosanoid metabolism  Academic Article
• A novel 2 '-(n-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models  Academic Article
• A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma  Academic Article
• A novel ELISA for mouse activated protein C in plasma  Academic Article
• A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target  Academic Article
• A novel Netrin-l-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching  Academic Article
• A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease  Academic Article
• A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells  Academic Article
• A novel and simple method for culturing pericytes from mouse brain  Academic Article
• A novel approach for in vivo measurement of mouse red cell redox status  Academic Article
• A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system  Academic Article
• A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis  Academic Article
• A novel class II MHC molecule with unusual tissue distribution  Academic Article
• A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties  Academic Article
• A novel cross-talk in diacylglycerol signaling the rac-gap beta 2-chimaerin is negatively regulated by protein kinase c delta-mediated phosphorylation  Academic Article
• A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1  Academic Article
• A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects  Academic Article
• A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis  Academic Article
• A novel generation of heparan sulfate mimetics for the treatment of prion diseases  Academic Article
• A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation  Academic Article
• A novel method for generating region-specific monoclonal-antibodies to modified proteins - application to the identification of human glucosylated low-density lipoproteins  Academic Article
• A novel method to establish microglia-free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia  Academic Article
• A novel monoclonal antibody, L1A3, is directed to the functional site of the αv integrin subunit  Academic Article
• A novel neuron-specific DNA end-binding factor in the murine brain  Academic Article
• A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action  Academic Article
• A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease  Academic Article
• A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β  Academic Article
• A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal cns  Academic Article
• A novel synthetic bipartite carrier protein for developing glycotope-based vaccines  Academic Article
• A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system  Academic Article
• A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines  Academic Article
• A novel vascular endothelial growth factor heparin-binding domain substructure binds to glycosaminoglycans in vivo and localizes to tumor microvascular endothelium  Academic Article
• A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests  Academic Article
• A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct  Academic Article
• A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects  Academic Article
• A pRb-responsive, RGD-modified, and Hyaluronidase-armed Canine Oncolytic Adenovirus for Application in Veterinary Oncology  Academic Article
• A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity  Academic Article
• A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration  Academic Article
• A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas  Academic Article
• A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects  Academic Article
• A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice  Academic Article
• A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones  Academic Article
• A peripheral and central t-cell antigen recognized by a monoclonal thymocytotoxic autoantibody from new-zealand black mice  Academic Article
• A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries  Academic Article
• A phase i/ib trial of murine monoclonal anti-gd2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma - a report of the children's cancer group  Academic Article
• A phase-i study of human mouse chimeric antiganglioside gd2 antibody ch14.18 in patients with neuroblastoma  Academic Article
• A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins  Academic Article
• A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia  Academic Article
• A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein  Academic Article
• A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase ii in t cells: From activation to unresponsiveness  Academic Article
• A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer's disease mice  Academic Article
• A platform stratifying a sequestering agent and a pharmacological antagonist as a means to negate botulinum neurotoxicity  Academic Article
• A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice  Academic Article
• A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding  Academic Article
• A population of murine gamma delta T cells that recognize an inducible MHC class Ib molecule  Academic Article
• A porous silicon-based optical interferometric biosensor  Academic Article
• A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic  Academic Article
• A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis  Academic Article
• A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo  Academic Article
• A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake  Academic Article
• A potential suppressive effect of natural antisense IL-1β RNA on lipopolysaccharide-induced IL-1β expression  Academic Article
• A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis  Academic Article
• A proapoptotic peptide for the treatment of solid tumors  Academic Article
• A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale  Academic Article
• A putative bacterial ABC transporter circumvents the essentiality of signal peptidase  Academic Article
• A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes  Academic Article
• A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions  Academic Article
• A rabbit antiserum detects a vh j558 subgroup marker highly expressed among anti-alprenolol antibodies  Academic Article
• A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation  Academic Article
• A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists  Academic Article
• A rationally designed agonist antibody fragment that functionally mimics thrombopoietin  Academic Article
• A receptor-induced by lymphocyte-activation (ILA) - a new member of the human nerve-growth-factor tumor-necrosis-factor receptor family  Academic Article
• A recombinant antibody interleukin-2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice  Academic Article
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• Bortezomib inhibits hepatitis B virus replication in transgenic mice  Academic Article
• Both E12 and E47 allow commitment to the B cell lineage  Academic Article
• Both anti-cd11a (lfa-i) and anti-cd11b (mac-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis  Academic Article
• Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt  Academic Article
• Both protein S and Gas6 stimulate outer segment phagocytosis by cultured rat retinal pigment epithelial cells  Academic Article
• Both the epitope specificity and isotype are important in the antitumor effect of monoclonal antibodies against Her-2/neu antigen  Academic Article
• Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury  Academic Article
• Brain region mapping using global metabolomics  Academic Article
• Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina  Academic Article
• Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice  Academic Article
• Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor  Academic Article
• Brain-specific knock-out of hypoxia-inducible factor-1α reduces rather than increases hypoxic-ischemic damage  Academic Article
• Branched fatty acid esters of hdroxy fatty acids (FAHFAs) protect against colitis by regulating gut innate and adaptive immune responses  Academic Article
• Breadth of tuning and taste coding in mammalian taste buds  Academic Article
• Break for SCIDs  Academic Article
• Break of T cell ignorance to a viral antigen in the liver induces hepatitis  Academic Article
• Breaking the one antibody-one target axiom  Academic Article
• Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice  Academic Article
• Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection  Academic Article
• Breast cancer cell lines grown in vivo: What goes in isn't always the same as what comes out  Academic Article
• Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts  Academic Article
• Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis  Academic Article
• Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist  Academic Article
• Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin  Academic Article
• Broadly neutralizing antibodies abrogate established hepatitis C virus infection  Academic Article
• Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge  Academic Article
• Bromodomain proteins contribute to maintenance of bloodstream form stage identity in the African trypanosome  Academic Article
• Brown adipogenic reprogramming induced by a small molecule  Academic Article
• Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1  Academic Article
• Building better vasculature  Academic Article
• Building zinc fingers by selection - toward a therapeutic application  Academic Article
• Bulk segregation mapping of mutations in closely related strains of mice  Academic Article
• Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system  Academic Article
• Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax  Academic Article
• C-fos deficiency inhibits induction of mrna for some, but not all, neurotransmitter biosynthetic enzymes by immobilization stress  Academic Article
• C-fos is not essential for v-abl-induced lymphomagenesis  Academic Article
• C-fos is required for malignant progression of skin tumors  Academic Article
• C-jun causes focus formation and anchorage-independent growth in culture but is nontumorigenic  Academic Article
• C-myc augments gamma irradiation-induced apoptosis by suppressing bcl-x-l  Academic Article
• C-myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways  Academic Article
• C-myc is essential for vasculogenesis and angiogenesis during development and tumor progression  Academic Article
• C-myc-mediated regulation of telomerase activity is disabled in immortalized cells  Academic Article
• C-src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (bmk1)  Academic Article
• C-terminal ecfp fusion impairs synaptotagmin 1 function - crowding out synaptotagmin 1  Academic Article
• C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment  Academic Article
• C5L2, a nonsignaling C5A binding protein  Academic Article
• CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells  Academic Article
• CCR5 knockout prevents neuronal injury and behavioral impairment induced in a transgenic mouse model by a CXCR4-using HIV-1 glycoprotein 120  Academic Article
• CD14 is a pattern recognition receptor  Academic Article
• CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth  Academic Article
• CD200 expression on tumor cells suppresses antitumor immunity: new approaches to cancer immunotherapy  Academic Article
• CD4 is expressed on murine pluripotent hematopoietic stem cells  Academic Article
• CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer  Academic Article
• CD4(+) T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8(+) T-cell immune responses  Academic Article
• CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS)  Academic Article
• CD4+ T cells from IRF-1-deficient mice exhibit altered patterns of cytokine expression and cell subset homeostasis  Academic Article
• CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction  Academic Article
• CD4+ T-cell help in the tumor milieu is required for recruitment and cytolytic function of CD8+ T lymphocytes  Academic Article
• CD4+8- and CD4-8+ mature thymocytes require different post-selection processing for final development  Academic Article
• CD4+CD8- thymocytes from neonatal mice induce IgM production in SCID mice  Academic Article
• CD4-CD8- thymocytes that express the T-cell receptor may have previously expressed CD8  Academic Article
• CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5  Academic Article
• CD40 activation rescues antiviral CD8+ T cells from PD-1-mediated exhaustion  Academic Article
• CD8 T cell defect of TNF-α and IL-2 in DNAM-1 deficient mice delays clearance in vivo of a persistent virus infection.  Academic Article
• CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes  Academic Article
• CD8(+) T cell-mediated spontaneous diabetes in neonatal mice  Academic Article
• CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection  Academic Article
• CD8(+) T-Cell Epitope Mapping for Pneumonia Virus of Mice in H-2(b) Mice  Academic Article
• CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles  Academic Article
• CD8+ memory T cells appear exhausted within hours of acute virus infection  Academic Article
• CD8αα and ‐αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I  Academic Article
• CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis  Academic Article
• CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma  Academic Article
• CFTR Folding Consortium: methods available for studies of CFTR folding and correction  Academic Article
• CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells  Academic Article
• CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts  Academic Article
• CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation  Academic Article
• CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase  Academic Article
• CREB: The unindicted cancer co-conspirator  Academic Article
• CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement  Academic Article
• CRY links the circadian clock and CREB-mediated gluconeogenesis  Academic Article
• CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma  Academic Article
• CTCF-cohesin complex: architect of chromatin structure regulates V(D)J rearrangement  Academic Article
• CTL access to tissue antigen is restricted in vivo  Academic Article
• CTL escape viral variants. II. Biologic activity in vivo  Academic Article
• CTLA-4 blockade enhances the CTL responses to the p53 self-tumor antigen  Academic Article
• CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria  Academic Article
• CTLA4 expression is an indicator and regulator of steady-state CD4(+)FoxP3(+) T cell homeostasis  Academic Article
• CVS-3983, a selective matriptase inhibitor, suppresses the growth of androgen independent prostate tumor xenografts  Academic Article
• CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation  Academic Article
• CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice  Academic Article
• CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling  Academic Article
• CXCR4 expression in prostate cancer progenitor cells  Academic Article
• CaMKII activation in the entorhinal cortex disrupts previously encoded spatial memory  Academic Article
• Cabozantinib resolves bone scans in tumor-naïve mice harboring skeletal injuries  Academic Article
• Cachectin tumor necrosis factor stimulates collagenase and prostaglandin-e2 production by human synovial-cells and dermal fibroblasts  Academic Article
• Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo  Academic Article
• Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells  Academic Article
• Cadherin 23 is a component of the tip link in hair-cell stereocilia  Academic Article
• Caenorhabditis elegans TRPA-1 functions in mechanosensation  Academic Article
• Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually dimorphic manner  Academic Article
• Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues  Academic Article
• CalFluors: A universal motif for fluorogenic azide probes across the visible spectrum  Academic Article
• Calcineurin is a common target of cyclophilin-cyclosporine-a and fkbp-fk506 complexes  Academic Article
• Calcineurin negatively regulates tlr-mediated activation pathways  Academic Article
• Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation  Academic Article
• Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts  Academic Article
• Calcium dynamics are altered in cortical neurons lacking the calmodulin-binding protein RC3  Academic Article
• Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity  Academic Article
• Calpain-mediated down-regulation of myelin-associated glycoprotein in lysophosphatidic acid-induced neuropathic pain  Academic Article
• Camkii regulates the frequency-response function of hippocampal synapses for the production of both ltd and ltp  Academic Article
• Can gene delivery close the door to HIV-1 entry after escape?  Academic Article
• Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4t1 murine breast cancer model  Academic Article
• Cancer gene therapy using a novel secretable trimeric trail  Academic Article
• Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts  Academic Article
• Cancer: Aneuploidy drives a mutator phenotype in cancer  Academic Article
• Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: An expanded convergent functional genomics approach  Academic Article
• Cannabinoid CB1 receptors regulate neuronal TNF-alpha effects in experimental autoimmune encephalomyelitis  Academic Article
• Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis  Academic Article
• Carbonic anhydrase inhibitors. Interaction of 2-n,n-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: Kinetic and x-ray crystallographic studies  Academic Article
• Carboxylesterase isoenzyme specific deacylation of diacetoxyscirpenol (anguidine)  Academic Article
• Carcinogen-binding proteins. High-affinity binding sites for benzo[a]pyrene in mouse liver distinct from the ah receptor  Academic Article
• Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo  Academic Article
• Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis  Academic Article
• Cargo selection by the COPII budding machinery during export from the ER  Academic Article
• Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1  Academic Article
• Casein kinase 1 delta-dependent Wee1 protein degradation  Academic Article
• Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis  Academic Article
• Caspase cascades in human immunodeficiency virus-associated neurodegeneration  Academic Article
• Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles  Academic Article
• Cat-ELCCA: A robust method to monitor the fattty acid acyltransferase activityy of Grehlin O-Acyltransferase (GOAT)  Academic Article
• Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: Crystal structures of abzyme 21D8  Academic Article
• Catalytic antibodies - the rerouting of chemical-reactions  Academic Article
• Catalytic antibodies with lipase activity and R-substrate or S-substrate selectivity  Academic Article
• Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice  Academic Article
• Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes  Academic Article
• Catalytic soman scavenging by the Y337A/F338A acetylcholinesterase mutant assisted with novel site-directed aldoximes  Academic Article
• Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2  Academic Article
• Catecholamines in mutant mouse cerebellum - fluorescence microscopic and chemical studies  Academic Article
• Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity  Academic Article
• Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia  Academic Article
• Cbp histone acetyltransferase activity is a critical component of memory consolidation  Academic Article
• Cbp/p300 taz1 domain forms a structured scaffold for ligand binding  Academic Article
• Cc chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: Critical role in migration from the tumor site to draining lymph nodes  Academic Article
• Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry  Academic Article
• Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue  Academic Article
• Cd11a/cd18 (lfa-1) integrin engagement enhances biosynthesis of early cytokines by activated t-cells  Academic Article
• Cd14 - cell-surface receptor and differentiation marker  Academic Article
• Cd14 is required for myd88-independent lps signaling  Academic Article
• Cd2-deficient mice generate virus-specific cytotoxic t-lymphocytes upon infection with lymphocytic choriomeningitis virus  Academic Article
• Cd22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of b cells  Academic Article
• Cd22 regulates adaptive and innate immune responses of b cells  Academic Article
• Cd22-antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at c-2 and c-9 of sialic acid scaffold  Academic Article
• Cd28 plays a critical role in the segregation of pkc theta within the immunologic synapse  Academic Article
• Cd36 is a sensor of diacylglycerides  Academic Article
• Cd38 signaling in b lymphocytes is controlled by its ectodomain but occurs independently of enzymatically generated adp-ribose or cyclic adp-ribose  Academic Article
• Cd4 t cell control primary measles virus infection of the cns: Regulation is dependent on combined activity with either cd8 t cells or with b cells: Cd4, cd8 or b cells alone are ineffective  Academic Article
• Cd4(+) t cells induced by a DNA vaccine: Immunological consequences of epitope-specific lysosomal targeting  Academic Article
• Cd4-deficient mice have reduced levels of memory cytotoxic t lymphocytes after immunization and show diminished resistance to subsequent virus challenge  Academic Article
• Cd40 ligand-mediated interactions are involved in the generation of memory cd8(+) cytotoxic t lymphocytes (ctl) but are not required for the maintenance of ctl memory following virus infection  Academic Article
• Cd40l-deficient mice show deficits in antiviral immunity and have an impaired memory cd8(+) ctl response  Academic Article
• Cd44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma  Academic Article
• Cd69 down-modulation and inhibition of thymic egress by short- and long-term selective chemical agonism of sphingosine 1-phosphate receptors  Academic Article
• Cd8 t cells are sufficient to mediate allorecognition and allograft rejection  Academic Article
• Cd81 and cd28 costimulate t cells through distinct pathways  Academic Article
• Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway  Academic Article
• Cdnas of cell-adhesion molecules of different specificity induce changes in cell-shape and border formation in cultured s180 cells  Academic Article
• Cell and agonist-specific regulation of genes for matrix metalloproteinases and their tissue inhibitors by primary glial cells  Academic Article
• Cell co-culture patterning using aqueous two-phase systems  Academic Article
• Cell cooperation during in vivo anti-hapten antibody responses. VI. Evidence for an allogeneic effect replacing one of two helper T cells  Academic Article
• Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta 4 cytoplasmic domain  Academic Article
• Cell cycle-dependent immune lysis of moloney virus-transformed lymphocytes: Presence of viral antigen, accessibility to antibody, and complement activation  Academic Article
• Cell death, DNA breaks and possible rearrangements: an alternative view  Academic Article
• Cell entry of lymphocytic choriomeningitis virus is restricted in myotubes  Academic Article
• Cell fractionation and arrangement on fibers, beads, and surfaces  Academic Article
• Cell interactions in the primary immune response in vitro: A requirement for specific cell clusters  Academic Article
• Cell proliferation and cytokine production by CD4+ cells from old mice  Academic Article
• Cell proliferation and expression of cytokeratin filaments in F9 embryonal carcinoma cells  Academic Article
• Cell sorting-out is modulated by both the specificity and amount of different cell-adhesion molecules (cams) expressed on cell-surfaces  Academic Article
• Cell spreading controls endoplasmic and nuclear calcium: A physical gene regulation pathway from the cell surface to the nucleus  Academic Article
• Cell surface 4-1bbl mediates sequential signaling pathways 'downstream' of tlr and is required for sustained tnf production in macrophages  Academic Article
• Cell surface immunoglobulin regulated checkpoints in chicken B cell development  Academic Article
• Cell surface receptors in lysophospholipid signaling  Academic Article
• Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-jun-n-terminal kinase activation in cultured neurons  Academic Article
• Cell-adhesion alters gene-transcription in chicken-embryo brain-cells and mouse embryonal carcinoma-cells  Academic Article
• Cell-adhesion molecules  Academic Article
• Cell-adhesion molecules as targets for hox genes - neural cell-adhesion molecule promoter activity is modulated by cotransfection with hox-2.5 and hox-2.4  Academic Article
• Cell-adhesion molecules: A molecular basis for animal form  Academic Article
• Cell-autonomous circadian clock of hepatocytes drives rhythms in transcription and polyamine synthesis  Academic Article
• Cell-autonomous hepatic circadian clock regulates polyamine synthesis  Academic Article
• Cell-based optimization of novel benzamides as potential antimalarial leads  Academic Article
• Cell-cell interactions in antibody production  Academic Article
• Cell-free expression of disulfide-containing eukaryotic proteins for structural biology  Academic Article
• Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development  Academic Article
• Cell-free synthesis and segregation of beta-2-microglobulin  Academic Article
• Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific cd8(+) t cell deletion and viral persistence in vivo  Academic Article
• Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice  Academic Article
• Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages  Academic Article
• Cell-specific down-regulation of the beta(3)-adrenergic receptor  Academic Article
• Cell-specific susceptibility to prion strains is a property of the intact cell  Academic Article
• Cell-surface structures involved in t-cell activation  Academic Article
• Cell-type independent myc target genes reveal a primordial signature involved in biomass accumulation  Academic Article
• Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: a consequence of peptide-dependent allorecognition  Academic Article
• Cells that express viral-antigens but lack h-2 determinants are not lysed by immune thymus-derived lymphocytes but are lysed by other antiviral immune attack mechanisms  Academic Article
• Cellular and molecular heterogeneity of h-2kk antigens  Academic Article
• Cellular and molecular mechanisms of memory: The ltp connection  Academic Article
• Cellular applications of a sensitive and selective fiber optic nitric oxide biosensor based on a dye-labeled heme domain of soluble guanylate cyclase  Academic Article
• Cellular deficit in thymectomized mice  Academic Article
• Cellular events associated with immunogenesis of anti-erythrocyte autoantibody responses of nzb mice  Academic Article
• Cellular events associated with regression and progression of murine (Moloney) sarcomas  Academic Article
• Cellular immune and cytokine pathways resulting in tissue factor expression and relevance to septic shock  Academic Article
• Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy  Academic Article
• Cellular localization of type 1 plasminogen activator inhibitor messenger RNA and protein in murine renal tissue  Academic Article
• Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5  Academic Article
• Cellular prion protein conformation and function  Academic Article
• Cellular requirements for antigen presentation in the induction of a thymus-independent antibody response in vitro  Academic Article
• Cellular requirements for the primary in vitro antibody response to DNP-ficoll  Academic Article
• Cellular signaling by an agonist-activated receptor g(s)alpha fusion protein  Academic Article
• Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene  Academic Article
• Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes  Academic Article
• Central nervous system (cns)-resident natural killer cells suppress th17 responses and cns autoimmune pathology  Academic Article
• Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle  Academic Article
• Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones  Academic Article
• Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome  Academic Article
• Ceramide mediates the rapid phase of febrile response to IL-1β  Academic Article
• Ceramide triggers budding of exosome vesicles into multivesicular endosomes  Academic Article
• Cerebellar granule neurons develop elevated calcium responses when treated with interleukin-6 in culture  Academic Article
• Cerebellar lipid differences between r6/1 transgenic mice and humans with huntington's disease  Academic Article
• Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis  Academic Article
• Cerebrospinal fluid amyloid-beta (A beta) as an effect biomarker for brain A beta lowering verified by quantitative preclinical analyses  Academic Article
• Change in susceptibility of c3h-hej mice to lcm virus-infection  Academic Article
• Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse  Academic Article
• Changes in striatal signaling induce remodeling of RGS complexes containing G beta 5 and R7BP subunits  Academic Article
• Changes in the cytoplasmic structure of ctls during target cell recognition and killing  Academic Article
• Changes in the extent of microtubule assembly can regulate initiation of DNA-synthesis  Academic Article
• Channeling pain  Academic Article
• Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes  Academic Article
• Characterization and TCR variable region gene use of mouse resident nasal gamma delta T lymphocytes  Academic Article
• Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons  Academic Article
• Characterization and kinetics of synthesis of (15)S β-globin RNA, a putative precursor of β-globin mRNA   Academic Article
• Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices  Academic Article
• Characterization in vitro and engraftment potential in vivo of human progenitor t cells generated from hematopoietic stem cells  Academic Article
• Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays  Academic Article
• Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas  Academic Article
• Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture  Academic Article
• Characterization of H7N9 influenza A viruses isolated from humans  Academic Article
• Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis  Academic Article
• Characterization of TCR gene rearrangements during adult murine T cell development  Academic Article
• Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.  Academic Article
• Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo  Academic Article
• Characterization of a membrane-surface glycoprotein associated with t-cell activation  Academic Article
• Characterization of a neuronal interleukin-1 receptor and the corresponding mRNA in the mouse anterior pituitary cell line AtT-20  Academic Article
• Characterization of a side population of astrocytoma cells in response to temozolomide  Academic Article
• Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential  Academic Article
• Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance  Academic Article
• Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity  Academic Article
• Characterization of an anti-ly-6 monoclonal-antibody which defines and activates cytolytic lymphocytes-t  Academic Article
• Characterization of an ig v-h idiotope that results in specific homophilic binding and increased avidity for antigen  Academic Article
• Characterization of antibody responses to purified hiv-1 gp120 glycoproteins fused with the molecular adjuvant c3d  Academic Article
• Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice  Academic Article
• Characterization of highper, an enu-induced mouse mutant with abnormal psychostimulant and stress responses  Academic Article
• Characterization of ia antigens in mouse serum  Academic Article
• Characterization of immature CD4+CD8-CD3- thymocytes  Academic Article
• Characterization of lpa(2) (edg4) and lpa(1)/lpa(2) (edg2/edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)  Academic Article
• Characterization of lymphocytic choriomeningitis virus-binding protein(s) - a candidate cellular receptor for the virus  Academic Article
• Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection  Academic Article
• Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo  Academic Article
• Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism  Academic Article
• Characterization of monoclonal-antibody 155.8 and partial characterization of its proteoglycan antigen on human-melanoma cells  Academic Article
• Characterization of mouse mutants with abnormal RPE cells  Academic Article
• Characterization of multidrug resistance in SEWA mouse tumor cells: increased glutathione transferase activity and reversal of resistance with verapamil  Academic Article
• Characterization of murine a-raf, a new oncogene related to the v-raf oncogene  Academic Article
• Characterization of murine cytolytic-helper hybrid t-cell clones  Academic Article
• Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo  Academic Article
• Characterization of nuclear RNases that cleave hepatitis B virus RNA near the LA protein binding site  Academic Article
• Characterization of reciprocal MRL-Fas(lpr) and C57BL/6-Fas(lpr) congenic mice reveals significant effects from Lmb3  Academic Article
• Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro  Academic Article
• Characterization of splenic lymphoid cells in fetal and newborn mice  Academic Article
• Characterization of stem cell-like cancer cells in immune-competent mice  Academic Article
• Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands  Academic Article
• Characterization of the early stages of thymic NKT cell development  Academic Article
• Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study  Academic Article
• Characterization of the first potent and selective PDE9 inhibitor using a cGMP reporter cell line  Academic Article
• Characterization of the inflammatory response during acute measles encephalitis in nse-cd46 transgenic mice  Academic Article
• Characterization of the murine antigenic determinant, designated l3t4a, recognized by monoclonal-antibody gk1.5 - expression of l3t4a by functional t-cell clones appears to correlate primarily with class ii mhc antigen-reactivity  Academic Article
• Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase  Academic Article
• Characterization of the transformation-specific sequences of avian erythroblastosis virus in normal vertebrate cells  Academic Article
• Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases  Academic Article
• Characterization of two monoclonal antibodies against human tissue-type plasminogen activator  Academic Article
• Characterization of vascular adhesion molecules that may facilitate progenitor homing in the post-natal mouse thymus  Academic Article
• Characterization, design, and function of the mitochondrial proteome: from organs to organisms  Academic Article
• Characterization, serological specificity, and diagnostic possibilities of monoclonal-antibodies against legionella-pneumophila  Academic Article
• Characterizing the composition of molecular motors on moving axonal cargo using "cargo mapping" analysis  Academic Article
• Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis  Academic Article
• Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect  Academic Article
• Charcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levels  Academic Article
• Checkpoints in memory b-cell evolution  Academic Article
• Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens  Academic Article
• Chemical activation of the mechanotransduction channel Piezo1  Academic Article
• Chemical and biological investigations of β-oligoarginines  Academic Article
• Chemical and mutagenic investigations of fatty acid amide hydrolase: Evidence for a family of serine hydrolases with distinct catalytic properties  Academic Article
• Chemical dissection of mammalian spermatozoa  Academic Article
• Chemical dissection of mammalian spermatozoa  Academic Article
• Chemical generation of bispecific antibodies  Academic Article
• Chemical genetics of Plasmodium falciparum  Academic Article
• Chemical markers of transplantation individuality solubilized with sonic energy  Academic Article
• Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes  Academic Article
• Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing  Academic Article
• Chemical proteomic probes for profiling cytochrome P450 activities and drug interactions in vivo  Academic Article
• Chemical proteomics with sulfonyl fluoride probes reveals selective labeling of functional tyrosines in glutathione transferases  Academic Article
• Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1  Academic Article
• Chemical selection for catalysis in combinatorial antibody libraries  Academic Article
• Chemical strategies for stem cell biology and regenerative medicine  Academic Article
• Chemical synthesis of idiotopes - evidence that antisera to the same jh1 peptide detect multiple binding site-associated idiotopes  Academic Article
• Chemically programmed antibodies: Endothelin receptor targeting covx-bodies (tm)  Academic Article
• Chemically programmed bispecific antibody targeting legumain protease and avß3 integrin mediates strong antitumor effects  Academic Article
• Chemokine expression by intraepithelial gamma delta t cells - implications for the recruitment of inflammatory cells to damaged epithelia  Academic Article
• Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes  Academic Article
• Chemokine receptor CCR5 genotype influences the kinetics of human immunodeficiency virus type 1 infection in human PBL-SCID mice  Academic Article
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• Cox-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation  Academic Article
• Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers  Academic Article
• Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors  Academic Article
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• Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway  Academic Article
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• Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo  Academic Article
• Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo  Academic Article
• Coxsackievirus infection of the pancreas: Evaluation of receptor expression, pathogenesis, and immunopathology  Academic Article
• Coxsackievirus preferentially replicates and induces cytopathic effects in undifferentiated neural progenitor cells  Academic Article
• Coxsackievirus replication and the cell cycle: A potential regulatory mechanism for viral persistence/latency  Academic Article
• Coxsackievirus targets proliferating neuronal progenitor cells in the neonatal CNS  Academic Article
• Cre recombinase-mediated gene deletion in layer 4 of murine sensory cortical areas  Academic Article
• Creb coactivators direct anabolic responses and enhance performance of skeletal muscle  Academic Article
• Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity  Academic Article
• Critical evaluation of bispecific antibodies as targetins agents for boron neutron capture therapy of brain tumors  Academic Article
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• Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses  Academic Article
• Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response  Academic Article
• Critical role of transmethylation in TLR signaling and systemic lupus erythematosus  Academic Article
• Cross-linking cellular prion protein triggers neuronal apoptosis in vivo  Academic Article
• Cross-linking of lipopolysaccharide (lps) to cd14 on thp-1 cells mediated by lps-binding protein  Academic Article
• Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein  Academic Article
• Cross-neutralization of influenza a viruses mediated by a single antibody loop  Academic Article
• Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections 
• Cross-reactive and potent neutralizing antibody responses in human survivors of natural Ebolavirus infection  Academic Article
• Cross-reactivity between hl-a and h-2 antigens. Ii. Allogeneic sensitization by xenogeneic soluble lymphocyte antigens (hl-a)  Academic Article
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• Cryo-em visualization of an exposed rgd epitope on adenovirus that escapes antibody neutralization  Academic Article
• Cryopreservation by slow cooling with dmso diminished production of oct-4 pluripotency marker in human embryonic stem cells  Academic Article
• Cryopreservation of cancer-initiating cells derived from glioblastoma  Academic Article
• Cryopreservation of neurospheres derived from human glioblastoma multiforme  Academic Article
• Cryptic epitopes in n-terminally truncated prion protein are exposed in the full-length molecule: Dependence of conformation on ph  Academic Article
• Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis  Academic Article
• Cryptochromes mediate rhythmic repression of the glucocorticoid receptor  Academic Article
• Cryptochromes: bringing the blues to circadian rhythms  Academic Article
• Crystal structure determination of anti-DNA Fab A52  Academic Article
• Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif  Academic Article
• Crystal structure of NMC-4 fab anti-von Willebrand factor A1 domain  Academic Article
• Crystal structure of a cocaine-binding antibody  Academic Article
• Crystal structure of a conserved hypothetical protein (gi : 13879369) from Mouse at 1.90 A resolution reveals a new fold  Academic Article
• Crystal structure of a gamma delta t cell receptor ligand t22: A truncated mhc-like fold  Academic Article
• Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design  Academic Article
• Crystal structure of a putative NADPH-dependent oxidoreductase (GI : 18204011) from mouse at 2.10 Å resolution  Academic Article
• Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 a resolution  Academic Article
• Crystal structure of adenosine 5 '-phosphosulfate kinase from Penicillium chrysogenum  Academic Article
• Crystal structure of an Apo mRNA decapping enzyme (DcpS) from mouse at 1.83 Å resolution  Academic Article
• Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor  Academic Article
• Crystal structure of an mhc class i presented glycopeptide that generates carbohydrate-specific ctl  Academic Article
• Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove  Academic Article
• Crystal structure of mouse cd1d bound to the self ligand phosphatidylcholine: A molecular basis for nkt cell activation  Academic Article
• Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (trem-1) at 1.76 Å  Academic Article
• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser  Academic Article
• Crystal structure of the C-terminal domain of mouse TLR9  Academic Article
• Crystal structure of the TCR co-receptor CD8 alpha alpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution  Academic Article
• Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide  Academic Article
• Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran  Academic Article
• Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding  Academic Article
• Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A  Academic Article
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• Crystal structures of mouse CD1d-iGb3 complex and its cognate v alpha 14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids  Academic Article
• Crystal structures of two I-A(d)-peptide complexes reveal that high affinity can be achieved without large anchor residues  Academic Article
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• Crystal-structure of an h-2k(b)-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove  Academic Article
• Crystal-structure of murine cyclophilin-c complexed with immunosuppressive drug cyclosporine-a  Academic Article
• Crystal-structures of 2 viral peptides in complex with murine mhc class-i h-2k(b)  Academic Article
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• Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition-state analog  Academic Article
• Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides  Academic Article
• Crystallization, sequence, and preliminary crystallographic data for an antipeptide-fab-50.1 and peptide complexes with the principal neutralizing determinant of hiv-1 gp120  Academic Article
• Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization  Academic Article
• Ctl escape viral variants .1. Generation and molecular characterization  Academic Article
• Cultured astrocytes release a factor that decreases endothelin-1 secretion by brain microvessel endothelial-cells  Academic Article
• Cultures of astrocytes and microglia express interleukin 18  Academic Article
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• Cutting edge: Developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development  Academic Article
• Cutting edge: Early ifn-gamma signaling directly enhances primary antivliwal cd4(+) t cell responses  Academic Article
• Cutting edge: IL-13Rα1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide  Academic Article
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• Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver  Academic Article
• Cutting edge: Lack of high affinity competition for peptide in polyclonal cd4(+) responses unmasks il-4 production  Academic Article
• Cutting edge: Priming of NK cells by IL-18  Academic Article
• Cutting edge: Recent immune status determines the source of antigens that drive homeostatic t cell expansion  Academic Article
• Cutting edge: The tyrosine phosphatase SHP-1 regulates thymocyte positive selection  Academic Article
• Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection  Academic Article
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• Cyclic regulation of sensory perception by a female hormone alters behavior  Academic Article
• Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients  Academic Article
• Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcription  Academic Article
• Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes  Academic Article
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• Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities  Academic Article
• Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins  Academic Article
• Cyclin-dependent kinase-associated proteins cks1 and cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells  Academic Article
• Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity  Academic Article
• Cyclooxygenase-2: Where are we in 2003? Cardiovascular risk and cox-2 inhibitors  Academic Article
• Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex  Academic Article
• Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?  Academic Article
• Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception  Academic Article
• Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A  Academic Article
• Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile  Academic Article
• Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors  Academic Article
• Cytoimmunotherapy for persistent virus-infection reveals a unique clearance pattern from the central-nervous-system  Academic Article
• Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials  Academic Article
• Cytokine gene-therapy with interleukin-2-transduced fibroblasts - effects of il-2 dose on antitumor immunity  Academic Article
• Cytokine regulation of TNF-alpha mRNA and protein production by unprimed macrophages from C57Bl/6 and NZW mice  Academic Article
• Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct jak kinase signaling pathways  Academic Article
• Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells  Academic Article
• Cytokine-mediated survival from lethal herpes-simplex virus-infection - role of programmed neuronal death  Academic Article
• Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures  Academic Article
• Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase c-dependent activation of the alpha 6 beta 1 integrin  Academic Article
• Cytokines suppress apoptosis independent of increases in reactive oxygen levels  Academic Article
• Cytolytic T-lymphocyte response to isolated class I H-2 proteins and influenza peptides  Academic Article
• Cytomegalovirus causes a latent infection in undifferentiated cells and is activated by induction of cell-differentiation  Academic Article
• Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers  Academic Article
• Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes  Academic Article
• Cytoprotective-selective activated protein C attenuates pseudomonas aeruginosa-induced lung injury in mice  Academic Article
• Cytoprotective-selective activated protein C therapy for ischaemic stroke  Academic Article
• Cytoskeletal and morphologic impact of cellular oxidant injury  Academic Article
• Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies  Academic Article
• Cytosolic prion protein in neurons  Academic Article
• Cytotactin and its proteoglycan ligand mark structural and functional boundaries in somatosensory cortex of the early postnatal mouse  Academic Article
• Cytotactin binding - inhibition of stimulated proliferation and intracellular alkalinization in fibroblasts  Academic Article
• Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: interferon gamma, but not tumour necrosis factor alpha, displays antiviral activity in vivo  Academic Article
• Cytotoxic T-lymphocytes cleanse viral gene-products from individually infected neurons and lymphocytes in mice persistently infected with lymphocytic choriomeningitis virus  Academic Article
• Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice  Academic Article
• Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-jun n-terminal kinase  Academic Article
• D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain  Academic Article
• DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses  Academic Article
• DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis  Academic Article
• DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression  Academic Article
• DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization  Academic Article
• DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3  Academic Article
• DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria  Academic Article
• DNA immunization  Academic Article
• DNA immunization can stimulate florid local inflammation, and the antiviral immunity induced varies depending on injection site  Academic Article
• DNA immunization confers protection against lethal lymphocytic choriomeningitis virus-infection  Academic Article
• DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice  Academic Article
• DNA immunization to prevent autoimmune diabetes  Academic Article
• DNA immunization with minigenes: Low frequency of memory cytotoxic t lymphocytes and inefficient antiviral protection are rectified by ubiquitination  Academic Article
• DNA immunization: Effects of vehicle and route of administration on the induction of protective antiviral immunity  Academic Article
• DNA immunization: Ubiquitination of a viral protein enhances cytotoxic t-lymphocyte induction and antiviral protection but abrogates antibody induction  Academic Article
• DNA methylation and chromatin structure regulate T cell perforin gene expression  Academic Article
• DNA vaccination against vegf receptor 2 reduces atherosclerosis in ldl receptor-deficient mice  Academic Article
• DNA vaccination can break immunological tolerance to prp in wild-type mice and attenuates prion disease after intracerebral challenge  Academic Article
• DNA vaccination to treat autoimmune diabetes  Academic Article
• DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes  Academic Article
• DNA vaccines designed to inhibit tumor growth by suppression of angiogenesis  Academic Article
• DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis  Academic Article
• DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: Implications for eqtl mapping studies  Academic Article
• DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
• DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer  Academic Article
• DNA-sequences preceding the rabbit beta-globin gene are required for formation in mouse l cells of beta-globin rna with the correct 5' terminus  Academic Article
• DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis  Academic Article
• DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect  Academic Article
• DST4 - a new, and probably the last, functional DH gene in the BALB/c mouse  Academic Article
• Dab1 is required for synaptic plasticity and associative learning  Academic Article
• Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation  Academic Article
• Darwinian evolution of prions in cell culture  Academic Article
• Data-driven synthesis of proteolysis-resistant peptide hormones  Academic Article
• De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis  Academic Article
• Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function  Academic Article
• Decay-accelerating factor 1 (daf1) deficiency exacerbates xenobiotic-induced autoimmunity  Academic Article
• Deconstructing transcriptional heterogeneity in pluripotent stem cells  Academic Article
• Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo  Academic Article
• Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase  Academic Article
• Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system  Academic Article
• Decreased brain reward function during nicotine withdrawal in c57bl6 mice: Evidence from intracranial self-stimulation (icss) studies  Academic Article
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• Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy  Academic Article
• Dedifferentiation of lineage-committed cells by a small molecule  Academic Article
• Deep proteome mapping of mouse kidney based on OFFGel prefractionation reveals remarkable protein post- translational modifications  Academic Article
• Deep sequencing of the murine Igh repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies  Academic Article
• Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation  Academic Article
• Deep-brain magnetic stimulation promotes adult hippocampal neurogenesis and alleviates stress-related behaviors in mouse models for neuropsychiatric disorders  Academic Article
• Defective CD8+ T cell peripheral tolerance in nonobese diabetic mice  Academic Article
• Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene  Academic Article
• Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice  Academic Article
• Defective lymphotoxin-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice  Academic Article
• Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function  Academic Article
• Defects in deletional tolerance of CD8+ T cells in autoimmune diabetes  Academic Article
• Defects in skin γδ T cell function contribute to delayed wound repair in rapamycin-treated mice  Academic Article
• Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist  Academic Article
• Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy  Academic Article
• Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances  Academic Article
• Deficiency of DNA repair nuclease ERCC1-XPF promotes prostate cancer progression in a tissue recombination model  Academic Article
• Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis  Academic Article
• Deficiency of lrp8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis  Academic Article
• Deficiency of the cyclin kinase inhibitor P21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoirnmunity  Academic Article
• Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the pkr gene: Role of irf-1 and nf-kappa b  Academic Article
• Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity  Academic Article
• Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase  Academic Article
• Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice  Academic Article
• Defined and scalable differentiation of human oligodendrocyte precursors from pluripotent stem cells in a 3D culture system  Academic Article
• Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns  Academic Article
• Defining parameters for successful immunocytotherapy of persistent viral infection  Academic Article
• Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro  Academic Article
• Defining the conformational features of anchorless, poorly neuroinvasive prions  Academic Article
• Defining the critical hypoxic threshold that promotes vascular remodeling in the brain  Academic Article
• Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome  Academic Article
• Defining the risks of mesenchymal stromal cell therapy  Academic Article
• Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity  Academic Article
• Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis  Academic Article
• Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis  Academic Article
• Delayed and accelerated aging share common longevity assurance mechanisms  Academic Article
• Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors  Academic Article
• Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice  Academic Article
• Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization  Academic Article
• Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival  Academic Article
• Deletion of PREPl causes growth impairment and hypotonia in mice  Academic Article
• Deletion of ghrelin impairs neither growth nor appetite  Academic Article
• Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus  Academic Article
• Deletion of naive CD8 T cells requires persistent antigen and is not programmed by an initial signal from the tolerogenic APC  Academic Article
• Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice  Academic Article
• Deletion of p21 (WAF-1/Cip1) does not induce systemic autoimmunity in female BXSB mice  Academic Article
• Deletion of the nucleotide excision repair gene ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions  Academic Article
• Deletions linked to TP53 loss drive cancer through p53-independent mechanisms  Academic Article
• Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication  Academic Article
• Deliberate removal of T cell help improves virus-neutralizing antibody production  Academic Article
• Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects  Academic Article
• Delineation of a defect in t-cell receptor beta-genes of nzw mice predisposed to autoimmunity  Academic Article
• Delineation of spontaneous erythrocyte autoantibody responses of nzb and other strains of mice  Academic Article
• Delineation of the proinflammatory cytokine cascade in fever induction  Academic Article
• Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes  Academic Article
• Delta(9)-tetrahydrocannabinol immunochemical studies: Haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta(9)-tetrahydrocannabinol  Academic Article
• Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects  Academic Article
• Demonstration of a hematopoietic stem-cell antigen (SC-1) on a murine lymphoma and isolation of variants lacking the antigen  Academic Article
• Demonstration of dehydrogenases and monoamine-oxidase by formation of osmium blacks at sites of hatchetts brown  Academic Article
• Demonstration of developmental anomalies in mouse fetuses by transfer of murine cytomegalovirus DNA-injected eggs to surrogate mothers  Academic Article
• Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation  Academic Article
• Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation  Academic Article
• Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice  Academic Article
• Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity  Academic Article
• Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection  Academic Article
• Dendritic cells produce macrophage inflammatory protein-1 gamma, a new member of the CC chemokine family  Academic Article
• Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice  Academic Article
• Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis  Academic Article
• Dendritic epidermal T cells regulate skin antimicrobial barrier function  Academic Article
• Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1  Academic Article
• Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin  Academic Article
• Dense nuclear cataract caused by the γB-crystallin S11R point mutation  Academic Article
• Density-dependent stimulation and inhibition of cell-growth by agents that disrupt microtubules  Academic Article
• Dentate gyrus volume is reduced before onset of plaque formation in pdapp mice: A magnetic resonance microscopy and stereologic analysis  Academic Article
• Dentin conditioning codetermines cell fate in regenerative endodontics  Academic Article
• Dependence-induced increases in ethanol self-administration in mice are blocked by the crf, receptor antagonist antalarmin and by crf, receptor knockout  Academic Article
• Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation  Academic Article
• Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors  Academic Article
• Depletion of complement does not impact initiation of xenobiotic-induced autoimmune disease  Academic Article
• Depletion of fat-resident T-reg cells prevents age-associated insulin resistance  Academic Article
• Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
• Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions   Academic Article
• Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland  Academic Article
• Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway  Academic Article
• Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland  Academic Article
• Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes  Academic Article
• Derivation of microglia-free astrocyte cultures from neural stem cells  Academic Article
• Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse-transcriptase and suppress human and feline immunodeficiency virus expression in cultured-cells  Academic Article
• Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease  Academic Article
• Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor  Academic Article
• Design and discovery of N-(2-Methyl-5 '-morpholino-6 '-((tetrahydro-2H-pyran-4-yl)oxy)- 3,3 '-bipyridin -5-yl)-3-(trifluoromethyl)benzamide (RAF709): a potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers  Academic Article
• Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300  Academic Article
• Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives  Academic Article
• Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors  Academic Article
• Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase  Academic Article
• Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant  Academic Article
• Design of high-affinity major histocompatibility complex-specific antagonist peptides that inhibit cytotoxic lymphocyte-t activity - implications for control of viral disease  Academic Article
• Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d  Academic Article
• Design of polydactyl zinc-finger proteins for unique addressing within complex genomes  Academic Article
• Design of potent and proteolytically stable oxyntomodulin analogs  Academic Article
• Design of potent and selective 2-aminobenzimidazole-based p38 alpha MAP kinase inhibitors with excellent in vivo efficacy  Academic Article
• Design, synthesis and SAR of novel glucokinase activators  Academic Article
• Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold  Academic Article
• Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs  Academic Article
• Design, synthesis, and characterization of alpha-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase  Academic Article
• Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation  Academic Article
• Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors  Academic Article
• Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists  Academic Article
• Designing 3-D adipospheres for quantitative metabolic study  Academic Article
• Designing arenaviral vaccines  Academic Article
• Designing small-molecule switches for protein-protein interactions  Academic Article
• Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the central nervous system: Astrocytes fail to express major histocompatibility complex class i and ii molecules  Academic Article
• Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis  Academic Article
• Detecting expression of 5T4 in CTCs and tumor samples from NSCLC patients  Academic Article
• Detecting genetic variation in microarray expression data  Academic Article
• Detection and partial characterization of circulating immune-complexes with solid-phase anti-c3  Academic Article
• Detection of a recombinant murine leukemia virus-related glycoprotein on virus-negative thymoma cells  Academic Article
• Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging  Academic Article
• Detection of h-2 antigens in serum  Academic Article
• Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing  Academic Article
• Detection of low-avidity CD4(+) T cells using recombinant artificial APC: following the antiovalbumin immune response  Academic Article
• Detection of malignant melanoma with monoclonal antibodies  Academic Article
• Detection of naturally occurring antibodies to rna-dependent DNA-polymerase of murine leukemia-virus in kidney eluates of akr mice  Academic Article
• Detection of prion infectivity in fat tissues of scrapie-infected mice  Academic Article
• Detection of transforming oncogenes in rat colon tumors induced by direct perfusion with N-methyl-N-nitrosourea  Academic Article
• Detection of vitronectin mRNA in tissues and cells of the mouse  Academic Article
• Detection, identification, and partial characterization of serine proteases and esterases in biological-systems  Academic Article
• Determinants of P3 amplitude and response to alcohol in Native American Mission Indians  Academic Article
• Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone  Academic Article
• Development and maintenance of a b220(-) memory b cell compartment  Academic Article
• Development and mechanism of γ-secretase modulators for Alzheimer's disease  Academic Article
• Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15  Academic Article
• Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-beta-Hexosaminidase Inhibitors  Academic Article
• Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection  Academic Article
• Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models  Academic Article
• Development of all CD4 T lineages requires nuclear factor TOX  Academic Article
• Development of an affinity chromatography resin for the purification of carcinogen binding proteins from mouse liver  Academic Article
• Development of anti-CD74 antibody-drug conjugates to target glucocorticoids to immune cells  Academic Article
• Development of antigen-specific helper T cell responses in vivo: antigen-specific Th cell subsets  Academic Article
• Development of approaches to improve cell survival in myoblast transfer therapy  Academic Article
• Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens  Academic Article
• Development of chemical probes for investigation of salt-inducible kinase function in vivo  Academic Article
• Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris  Academic Article
• Development of ecdysone-regulated lentiviral vectors  Academic Article
• Development of functionally selective, small molecule agonists at kappa opioid receptors  Academic Article
• Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties  Academic Article
• Development of immature thymocytes - initiation of CD3, CD4, and CD8 acquisition parallels down-regulation of the interleukin-2 receptor alpha-chain  Academic Article
• Development of insulin resistance in mice lacking PGC-1α in adipose tissues  Academic Article
• Development of live-attenuated arenavirus vaccines based on codon deoptimization  Academic Article
• Development of lupus in BXSB mice is independent of IL-4  Academic Article
• Development of oseltamivir phosphonate congeners as anti-influenza agents  Academic Article
• Development of pegylated forms of recombinant rhodosporidium toruloides phenylalanine ammonia-lyase for the treatment of classical phenylketonuria  Academic Article
• Development of proneurogenic, neuroprotective small molecules  Academic Article
• Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p  Academic Article
• Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain  Academic Article
• Developmental biology: The early heart remodelled  Academic Article
• Developmental control of n-cam expression by hox and pax gene-products  Academic Article
• Developmental expression of sorting nexin 3 in the mouse central nervous system  Academic Article
• Developmental expression of the alpha(iel)beta(7) integrin on t-cell receptor-gamma-delta and t-cell receptor-alpha-beta t-cells  Academic Article
• Developmental neurobiology: A genetic cheshire cat?  Academic Article
• Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease  Academic Article
• Developmental regulation of Zbu1, a DNA-binding member of the SWI2/SNF2 family  Academic Article
• Developmental regulation of b lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection  Academic Article
• Developmental regulation of beta 1 integrins during angiogenesis in the central nervous system  Academic Article
• Developmentally distinct th cells control plasma cell production in vivo  Academic Article
• Developmentally ordered appearance of thymocytes expressing different t-cell antigen receptors  Academic Article
• Developmentally regulated use of alternative promoters creates a novel platelet-derived growth-factor receptor transcript in mouse teratocarcinoma and embryonic stem-cells  Academic Article
• Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin tumor-necrosis-factor synthesis at separate points in the signaling pathway  Academic Article
• Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands  Academic Article
• Dhhc5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells  Academic Article
• Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1  Academic Article
• Diabetes insipidus in mice with a mutation in aquaporin-2  Academic Article
• Diced electrophoresis gel assay for screening enzymes with specified activities  Academic Article
• Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice  Academic Article
• Diet and feeding pattern affect the diurnal dynamics of the gut microbiome  Academic Article
• Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or-4 receptors  Academic Article
• Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics  Academic Article
• Differences in experimental tumor-localization of dual-labeled monoclonal-antibody  Academic Article
• Differences in one-way active-avoidance learning in mice of 3 inbred strains  Academic Article
• Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive cd4(+) t-cells by anti-cd4 monoclonal-antibody (gk1.5) in young and aged mice  Academic Article
• Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice  Academic Article
• Differences in the liability to self-administer intravenous cocaine between c57bl/6xsjl and balb/cbyj mice  Academic Article
• Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP  Academic Article
• Different mechanisms of increased luminal stenosis after arterial injury in mice deficient for urokinase- or tissue-type plasminogen activator  Academic Article
• Different pathways mediate virus inducibility of the human ifn-alpha-1 and ifn-beta genes  Academic Article
• Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9  Academic Article
• Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes  Academic Article
• Differential T cell responses to residual viral antigen prolong CD4(+) T cell contraction following the resolution of infection  Academic Article
• Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively  Academic Article
• Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation  Academic Article
• Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen  Academic Article
• Differential effects of a new amphotericin B derivative, MS-8209, on mouse BSE and scrapie: Implications for the mechanism of action of polyene antibiotics  Academic Article
• Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice  Academic Article
• Differential effects of il-12 on the generation of alloreactive ctl mediated by murine and human dendritic cells: A critical role for nitric oxide  Academic Article
• Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice  Academic Article
• Differential effects of morphine, dpdpe, and u-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice  Academic Article
• Differential effects of morphine- and cocaine-induced nnos immunoreactivity in the dentate gyrus of hippocampus of mice lacking mu-opioid receptors  Academic Article
• Differential effects of n-peptidyl-o-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test  Academic Article
• Differential effects of pharmacologic and genetic modulation of NMDA receptor activity on HIV/gp120-induced neuronal damage in an in vivo mouse model  Academic Article
• Differential expression of 2 distinct xenotropic viruses in nzb mice  Academic Article
• Differential expression of the repertoire in in vitro and in vivo responses to minor alloantigens  Academic Article
• Differential gene expression in lps/ifn gamma activated microglia and macrophages: In vitro versus in vivo  Academic Article
• Differential gene expression in the developing lateral geniculate nucleus and medial geniculate nucleus reveals novel roles for Zic4 and Foxp2 in visual and auditory pathway development  Academic Article
• Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis  Academic Article
• Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis  Academic Article
• Differential internalization of hu14.18-il2 immunocytokine by nk and tumor cell: Impact on conjugation, cytotoxicity, and targeting  Academic Article
• Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy  Academic Article
• Differential mechanisms of morphine antinociceptive tolerance revealed in beta arrestin-2 knock-out mice  Academic Article
• Differential modulation by the stress axis of ethanol withdrawal seizure expression in WSP and WSR mice  Academic Article
• Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation  Academic Article
• Differential protective effects of connective tissue growth factor against Aβ neurotoxicity on neurons and glia.  Academic Article
• Differential regulation by multiple promoters of the gene encoding the neuron-restrictive silencer factor  Academic Article
• Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites  Academic Article
• Differential regulation of E2F and Sp1-mediated transcription by G1 cyclins  Academic Article
• Differential regulation of antiviral T-cell immunity results in stable CD8(+) but declining CD4(+) T-cell memory  Academic Article
• Differential regulation of beta-1-adrenergic and beta-2-adrenergic receptor protein and messenger-rna levels by glucocorticoids during 3t3-f442a adipose differentiation  Academic Article
• Differential regulation of cell motility and invasion by fak  Academic Article
• Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation  Academic Article
• Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone  Academic Article
• Differential regulation of vitronectin in mice and humans in vitro  Academic Article
• Differential role of melanocortin receptor subtypes in cachexia  Academic Article
• Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry  Academic Article
• Differential target cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice  Academic Article
• Differential utilization of upstream augs in the beta-secretase mrna suggests that a shunting mechanism regulates translation  Academic Article
• Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in g86r superoxide dismutase transgenic mice  Academic Article
• Differential-effects of cytotactin tenascin fusion proteins on intracellular ph and cell morphology  Academic Article
• Differential-effects of the cytoplasmic domains of cell-adhesion molecules on cell-aggregation and sorting-out  Academic Article
• Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice  Academic Article
• Differentiation of Mycoplasma mycoides subsp. mycoides from certain closely related caprine mycoplasmas by mycoplasmaemia and cross-protection tests in mice  Academic Article
• Differentiation of mouse keratinocytes is accompanied by pkc-dependent changes in ap-1 proteins  Academic Article
• Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTen-dependent mechanism  Academic Article
• Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors  Academic Article
• Diphosphoryl lipid-a from rhodopseudomonas-sphaeroides atcc 17023 blocks induction of cachectin in macrophages by lipopolysaccharide  Academic Article
• Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects  Academic Article
• Direct comparison of Dll1-and Dll4-mediated notch activation levels shows differential lymphomyeloid lineage commitment outcomes  Academic Article
• Direct ex vivo kinetic and phenotypic analyses of cd8(+) t-cell responses induced by DNA immunization  Academic Article
• Direct imaging of interactions between an icosahedral virus and conjugate f-ab fragments by cryoelectron microscopy and x-ray crystallography  Academic Article
• Direct immunofluorescent tissue culture assay for lymphocytic choriomeningitis virus  Academic Article
• Direct induction of cyclin d2 by myc contributes to cell cycle progression and sequestration of p27  Academic Article
• Direct interferon-gamma signalling and cd8(+) t cell memory  Academic Article
• Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe  Academic Article
• Direct regulation of clock expression by rev-erb  Academic Article
• Direct reprogramming of mouse fibroblasts to neural progenitors  Academic Article
• Direct targeting of αvβ3 integrin on tumor cells with a monoclonal antibody, Abegrin™  Academic Article
• Directed enzyme evolution guided by multidimensional analysis of substrate-activity space  Academic Article
• Discovering disease-associated enzymes by proteome reactivity profiling  Academic Article
• Discovering potent and selective reversible inhibitors of enzymes in complex proteomes  Academic Article
• Discovery and characterization of a mammalian amyloid disaggregation activity  Academic Article
• Discovery and characterization of an endogenous CXCR4 antagonist  Academic Article
• Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2  Academic Article
• Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)  Academic Article
• Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability  Academic Article
• Discovery metabolite profiling - forging functional connections between the proteome and metabolome  Academic Article
• Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer  Academic Article
• Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer  Academic Article
• Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia  Academic Article
• Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors  Academic Article
• Discovery of 3-cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo 2,3-b pyridin-5-yObenzamide: a potent, selective, and orally bioavailable retinoic acid receptor related orphan receptor C2 inverse agonist  Academic Article
• Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia  Academic Article
• Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system  Academic Article
• Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer  Academic Article
• Discovery of GlyT1 inhibitors with improved pharmacokinetic properties  Academic Article
• Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia  Academic Article
• Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-m ethyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through structure-based drug design: a high affinity irreversible inhibitor targeting oncogenic EGFR mutants with selectivity over wild-type EGFR  Academic Article
• Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition  Academic Article
• Discovery of a noncovalent, mutant-selective epidermal growth factor receptor inhibitor  Academic Article
• Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomain of CBP/EP300  Academic Article
• Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer  Academic Article
• Discovery of a proneurogenic, neuroprotective chemical  Academic Article
• Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design  Academic Article
• Discovery of a small molecule insulin mimetic with antidiabetic activity in mice  Academic Article
• Discovery of a small-molecule BMP sensitizer for human embryonic stem cell differentiation  Academic Article
• Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors  Academic Article
• Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements  Academic Article
• Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors  Academic Article
• Discovery of matrix metalloproteases selective and activated peptide-doxorubicin prodrugs as anti-tumor agents  Academic Article
• Discovery of native autoantigens via antigen surrogate technology: Application to type 1 diabetes  Academic Article
• Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design  Academic Article
• Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients  Academic Article
• Discovery of potent and bioavailable GSK-3β inhibitors  Academic Article
• Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors  Academic Article
• Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties  Academic Article
• Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators  Academic Article
• Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model  Academic Article
• Discovery of pyrrolo 1,2-b pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors  Academic Article
• Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na(v)1.7 inhibitors with pain efficacy in mice  Academic Article
• Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2)  Academic Article
• Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist  Academic Article
• Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (s1p(4)-r) agonists  Academic Article
• Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)  Academic Article
• Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3  Academic Article
• Discrete BDNF neurons in the paraventricular hypothalamus control feeding and energy expenditure  Academic Article
• Discriminated selection among viral peptides with the appropriate anchor residues - implications for the size of the cytotoxic t-lymphocyte repertoire and control of viral-infection  Academic Article
• Disease accompanying in utero viral infection. The role of maternal antibody in tissue injury after transplacental infection with lymphocytic choriomeningitis virus  Academic Article
• Disease model: Dissecting the pathogenesis of the measles virus  Academic Article
• Disease modifying potential of glatiramer acetate in Huntington's disease  Academic Article
• Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders  Academic Article
• Disialoganglioside gd3 on human-melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis  Academic Article
• Disproportionate inhibition of feeding in a(y) mice by certain stressors: A cautionary note  Academic Article
• Disproportionate recruitment of cd8(+) t cells into the central nervous system by professional antigen-presenting cells  Academic Article
• Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity  Academic Article
• Disruption of Gja8 (α8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation  Academic Article
• Disruption of angiogenesis by pex, a noncatalytic metalloproteinase fragment with integrin binding activity  Academic Article
• Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease  Academic Article
• Disruption of dendritic translation of camkii alpha impairs stabilization of synaptic plasticity and memory consolidation  Academic Article
• Disruption of differentiated functions during viral infection in vivo - v. Mapping of a locus involved in susceptibility of mice to growth hormone deficiency due to persistent lymphocytic choriomeningitis virus infection  Academic Article
• Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure  Academic Article
• Disruption of myd88 signaling suppresses hemophagocytic lymphohistiocytosis in mice  Academic Article
• Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal  Academic Article
• Disruption of the arf transcriptional activator dmp1 facilitates cell immortalization, ras transformation, and tumorigenesis  Academic Article
• Disruption of the arf-mdm2-p53 tumor suppressor pathway in myc-induced lymphomagenesis  Academic Article
• Disruption of the chaperonin containing TCP-1 function affects protein networks essential for rod outer segment morphogenesis and survival  Academic Article
• Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome  Academic Article
• Disruption of the plasminogen activator inhibitor-1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice  Academic Article
• Disruption of tissue-specific fucosyltransferase vii, an enzyme necessary for selectin ligand synthesis, suppresses atherosclerosis in mice  Academic Article
• Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice  Academic Article
• Dissecting influenza virus pathogenesis uncovers a novel chemical approach to combat the infection  Academic Article
• Dissecting the molecular anatomy of persistent infection with lymphocytic choriomeningitis virus  Academic Article
• Dissecting the molecular anatomy of the nervous system: analysis of RNA and protein expression in whole body sections of laboratory animals  Academic Article
• Dissecting the requirements for maintenance of the cmv-specific memory t-cell pool  Academic Article
• Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire  Academic Article
• Dissection of the BCL-2 family signaling network with stabilized alpha-helices of BCL-2 domains  Academic Article
• Dissection of the insulin-sensitizing effect of liver x receptor ligands  Academic Article
• Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice  Academic Article
• Dissociation of locomotor activation and suppression of food intake induced by crf in crfr1-deficient mice  Academic Article
• Dissociation of the effect of aminoglutethimide on corticosterone biosynthesis from ataxic and hypothermic effects in DBA and C57 mice  Academic Article
• Dissociation of the opioid receptor mechanisms that control mechanical and heat pain  Academic Article
• Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)  Academic Article
• Distinct APCs explain the cytokine bias of alpha-galactosylceramide variants in vivo  Academic Article
• Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region  Academic Article
• Distinct TCR signaling pathways drive proliferation and cytokine production in T cells  Academic Article
• Distinct and opposing roles for Rab27a/MIph/MyoVa and Rab27b/Munc13-4 in mast cell secretion  Academic Article
• Distinct antithrombotic consequences of platelet glycoprotein Ibα and VI deficiency in a mouse model of arterial thrombosis  Academic Article
• Distinct conformational spectrum of homologous multidrug ABC transporters  Academic Article
• Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III  Academic Article
• Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease  Academic Article
• Distinct endocytic mechanisms of cd22 (siglec-2) and siglec-f reflect roles in cell signaling and innate immunity  Academic Article
• Distinct footprints of tcr engagement with highly homologous ligands  Academic Article
• Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus  Academic Article
• Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure  Academic Article
• Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors  Academic Article
• Distinct rate and patterns of human CD4+ T-cell depletion in hu-PBL-SCID mice infected with different isolates of the human immunodeficiency virus  Academic Article
• Distinct requirements for deletion versus anergy during CD8 T cell peripheral tolerance in vivo  Academic Article
• Distinct role of long 3 ' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons  Academic Article
• Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci  Academic Article
• Distinct roles for astrocyte alpha v beta 5 and alpha v beta 8 integrins in adhesion and migration  Academic Article
• Distinct roles for somatically and dendritically synthesized brain-derived neurotrophic factor in morphogenesis of dendritic spines  Academic Article
• Distinct roles of cytoskeletal components in immunological synapse formation and directed secretion  Academic Article
• Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapse  Academic Article
• Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature b cells  Academic Article
• Distinct spatio-temporal Ca(2+) signaling elicited by integrin alpha 2 beta 1 and glycoprotein VI under flow  Academic Article
• Distinction between malignant l cells and normal mouse fibroblasts by rosette formation with sheep red blood-cells  Academic Article
• Distinctions in beta-adrenergic-receptor interactions with the magnesium-guanine nucleotide coupling proteins in turkey erythrocyte and s49-lymphoma membranes  Academic Article
• Distortion of cell functions by noncytotoxic viruses  Academic Article
• Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide  Academic Article
• Distribution of endotoxin (lipopolysaccharide) in tissues of lipopolysaccharide-responsive and lipopolysaccharide-unresponsive mice  Academic Article
• Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes  Academic Article
• Distribution of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected trigeminal ganglia in the mouse  Academic Article
• Distribution of vitronectin mRNA during murine development  Academic Article
• Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists  Academic Article
• Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors  Academic Article
• Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor  Academic Article
• Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα  Academic Article
• Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis  Academic Article
• Diverse roles of Eph/ephrin signaling in the mouse lens  Academic Article
• Diversity of T-cell receptors in virus-specific cytotoxic T lymphocytes recognizing three distinct viral epitopes restricted by a single major histocompatibility complex molecule  Academic Article
• Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis  Academic Article
• Division of labor of schwann cell integrins during migration on peripheral nerve extracellular matrix ligands  Academic Article
• Do t cells need endogenous peptides for activation?  Academic Article
• Does preferential Th subset activation contribute to the murine acquired immunodeficiency disease (MAIDS)?  Academic Article
• Does the major histocompatibility complex serve as a specific receptor for semliki forest virus  Academic Article
• Does toll-like receptor 3 play a biological role in virus infections?  Academic Article
• Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor  Academic Article
• Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3  Academic Article
• Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation  Academic Article
• Dominant cataracts result from incongruous mixing of wild-type lens connexins  Academic Article
• Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis  Academic Article
• Dopamine d1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral-responses  Academic Article
• Dopamine neurotransmission is involved in the attenuating effects of 5-ht3 receptor antagonist mdl 72222 on acute methamphetamine-induced locomotor hyperactivity in mice  Academic Article
• Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons  Academic Article
• Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice  Academic Article
• Dorsal raphe dopamine neurons modulate arousal and promote wakefulness by salient stimuli  Academic Article
• Dose response and timing effects in the therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate  Academic Article
• Dose- and time-dependent bimodal effects of kappa-opioid agonists on locomotor activity in mice  Academic Article
• Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake  Academic Article
• Double-strand DNA breaks recruit the centromeric histone CENP-A  Academic Article
• Double-stranded rna-mediated tlr3 activation is enhanced by cd14  Academic Article
• Down-regulation of MHC class-I antigen in insulinoma cells controlled by the R1 element of the H-2 enhancer  Academic Article
• Down-regulation of beta(3) adrenoreceptor gene expression in brown fat cells is transient and recovery is dependent upon a short-lived protein factor  Academic Article
• Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice  Academic Article
• Down-regulation of the major histocompatibility complex class-I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding  Academic Article
• Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin  Academic Article
• Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice  Academic Article
• Downregulation of transcription factor sox2 in cancer stem cells suppresses growth and metastasis of lung cancer  Academic Article
• Downregulation of tumor growth and invasion by redox-active nanoparticles  Academic Article
• Doxorubicin conjugated with a monoclonal-antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude-mice  Academic Article
• Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies  Academic Article
• Drug target validation: lethal infection blocked by inducible peptide  Academic Article
• Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition  Academic Article
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• DsAAV8-mediated gene transfer and beta-cell expression of IL-4 and beta-cell growth factors are capable of reversing early-onset diabetes in NOD mice  Academic Article
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• Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice  Academic Article
• Effects of antiproliferative cyclic-amp on interleukin 2-stimulated gene-expression  Academic Article
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• Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice  Academic Article
• Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta  Academic Article
• Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse  Academic Article
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• Effects of coptis japonica on morphine-induced conditioned place preference in mice  Academic Article
• Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch  Academic Article
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• Effects of environmental enrichment on gene expression in the brain  Academic Article
• Effects of ginseng total saponin on cocaine-induced hyperactivity and conditioned place preference in mice  Academic Article
• Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice  Academic Article
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• Effects of sodium metaperiodate on t and b lymphocytes  Academic Article
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• Effects of the endogenous PPAR-alpha agonist, oleoylethanolamide on MDMA-induced cognitive deficits in mice  Academic Article
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• Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs  Academic Article
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• Efficiency and effectiveness of cloned virus-specific cytotoxic T lymphocytes in vivo  Academic Article
• Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes  Academic Article
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• Efficient peripheral clonal elimination of b lymphocytes in mrl/lpr mice bearing autoantibody transgenes  Academic Article
• Efficient preparation of site-specific antibody-drug conjugates using cysteine insertion  Academic Article
• Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2  Academic Article
• Efficient t cell activation via a toll-interleukin 1 receptor-independent pathway  Academic Article
• Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone-marrow transduced by a retroviral vector  Academic Article
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• Enhanced tumorigenicity of an Epstein-Barr virus-transformed lymphoblastoid cell line is associated with a unique 1:18 chromosomal translocation and decreased expression of lymphocyte function associated antigen-1a (CD11A)  Academic Article
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• Enhancement of antibody-dependent cytotoxicity with a chimeric anti-gd2 antibody  Academic Article
• Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells  Academic Article
• Enhancement of autoimmune-disease using recombinant vaccinia virus encoding myelin proteolipid protein  Academic Article
• Enhancement of bone healing based on ex vivo gene therapy using human muscle-derived cells expressing bone morphogenetic protein 2  Academic Article
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• Enhancement of experimental allergic encephalomyelitis (eae) by DNA immunization with myelin proteolipid protein (plp) plasmid DNA  Academic Article
• Enhancement of fgf-like polypeptides in the retinae of newborn mice exposed to hyperoxia  Academic Article
• Enhancement of infectivity and oncogenicity of a murine leukemia-virus in adult mice by x-irradiation  Academic Article
• Enhancement of metastasis development by bcg immunotherapy  Academic Article
• Enhancement of reaginic and hemagglutinating antibody production by an extract of Bordetella pertussis containing histamine sensitizing factor  Academic Article
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• Enhancing nicotine vaccine immunogenicity with liposomes  Academic Article
• Enhancing or suppressive effects of antibodies on processing of a pathogenic T cell epitope in thyroglobulin  Academic Article
• Enhancing t cell activation and antiviral protection by introducing the hiv-1 protein transduction domain into a DNA vaccine  Academic Article
• Enrichment of regulatory signals in conserved non-coding genomic sequence  Academic Article
• Enrichment of viable lymphocytes in defined cycle phases by sorting on the basis of pulse width of axial light extinction  Academic Article
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• Enterotoxin residues determining t-cell receptor v-beta binding-specificity  Academic Article
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• Enumeration and functional evaluation of virus-specific cd4(+) and cd8(+) t cells in lymphoid and peripheral sites of coxsackievirus b3 infection  Academic Article
• Envelope exchange for the generation of live-attenuated arenavirus vaccines  Academic Article
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• EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens  Academic Article
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• Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation  Academic Article
• Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories  Academic Article
• Epigenetic regulation of pluripotency and differentiation  Academic Article
• Epithelial membrane protein-1 is a biomarker of gefitinib resistance  Academic Article
• Epithelial p38 alpha controls immune cell recruitment in the colonic mucosa  Academic Article
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• Epstein-Barr-virus complement C3d receptor is an interferon-alpha receptor  Academic Article
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• Eradication of human hepatic and pulmonary melanoma metastases in scid mice by antibody-interleukin 2 fusion proteins  Academic Article
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• Ercc1/xpf removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes  Academic Article
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• Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus  Academic Article
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• Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids  Academic Article
• Evaluation of c3 receptors on lymphoid cells with different complement sources  Academic Article
• Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain  Academic Article
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• Evaluation of fatty acid amides in the carrageenan-induced paw edema model  Academic Article
• Evaluation of gp160 vaccinees in the hu-PBL-SCID mouse model  Academic Article
• Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants  Academic Article
• Evaluation of immunoglobulins from plant-cells  Academic Article
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• Evaluation of orally administered pegylated phenylalanine ammonia lyase in mice for the treatment of phenylketonuria  Academic Article
• Evaluation of protective immunity to HIV-1 in human PBL-SCID mice  Academic Article
• Evaluation of quinacrine treatment for prion diseases  Academic Article
• Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose  Academic Article
• Evaluation of the echinocandin antifungal mk-0991 (l-743,872): Efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis  Academic Article
• Evasion of the p53 tumour surveillance network by tumour-derived myc mutants  Academic Article
• Event-related oscillations as risk markers in genetic mouse models of high alcohol preference  Academic Article
• Event-related oscillations in mice: Effects of stimulus characteristics  Academic Article
• Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling  Academic Article
• Evidence for a b-lymphocyte defect underlying anti-x anti-erythrocyte autoantibody response of nzb-mice  Academic Article
• Evidence for an underlying cd4 helper and cd8 t-cell defect in b-cell-deficient mice: Failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from mu mt/mu mt mice  Academic Article
• Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation  Academic Article
• Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle  Academic Article
• Evidence for genetic association of RORB with bipolar disorder  Academic Article
• Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens  Academic Article
• Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer  Academic Article
• Evidence in locomotion test for the functional heterogeneity of orl-1 receptors  Academic Article
• Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice  Academic Article
• Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus  Academic Article
• Evidence that TRPC1 is involved in hippocampal glutamate-induced cell death  Academic Article
• Evidence that a single nucleotide polymorphism in the promoter of the g protein receptor kinase 3 gene is associated with bipolar disorder  Academic Article
• Evidence that extrahepatic cells express vitronectin mRNA at rates approaching those of hepatocytes  Academic Article
• Evidence that gene activation and silencing during stem cell differentiation requires a transcriptionally paused intermediate state  Academic Article
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• Evidence that tRNA synthetase-directed proton transfer stops mistranslation  Academic Article
• Evidence that the hypermutated m protein of a subacute sclerosing panencephalitis measles virus actively contributes to the chronic progressive cns disease  Academic Article
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• Evolutionary genetics: CCR5 mutation and plague protection  Academic Article
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• Ex vivo cytosolic delivery of functional macromolecules to immune cells  Academic Article
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• Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models  Academic Article
• Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation  Academic Article
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• Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA  Academic Article
• Examining vascular remodeling in the hypoxic central nervous system  Academic Article
• Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits  Academic Article
• Exclusion of circulating t-cells from the thymus does not apply in the neonatal-period  Academic Article
• Exocytotic fusion is activated by rab3a peptides  Academic Article
• Exocytotic fusion pores are composed of both lipids and proteins  Academic Article
• Exogenous S1P exposure potentiates ischemic stroke damage that is reduced possibly by inhibiting S1P receptor signaling  Academic Article
• Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections  Academic Article
• Exogenous beta 2-microglobulin is required for antigenic peptide binding to isolated class I major histocompatibility complex molecules  Academic Article
• Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis  Academic Article
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• Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis  Academic Article
• Exosomes derived from genetically modified dc expressing fasl are anti-inflammatory and immunosuppressive  Academic Article
• Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice  Academic Article
• Exosomes released from mycoplasma infected tumor cells activate inhibitory B cells  Academic Article
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• Expanding the binding envelope of CYP51 inhibitors targeting Trypanosoma cruzi with 4-aminopyridyl-based sulfonamide derivatives  Academic Article
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• Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform  Academic Article
• Expanding the scope of site-specific recombinases for genetic and metabolic engineering  Academic Article
• Expansion and function of CD8(+) T cells, expressing Ly49 inhibitory receptors specific for MHC class I molecules  Academic Article
• Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes  Academic Article
• Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen  Academic Article
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• Experimental characterization of electrostatic and conformational heterogeneity in an SH3 domain  Academic Article
• Experimental skin lesions in mice resembling systemic lupus erythematosus  Academic Article
• Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4  Academic Article
• Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor  Academic Article
• Exploring spatiotemporal organization of SCN circuits  Academic Article
• Exploring the energy landscape of antibody-antigen complexes: Protein dynamics, flexibility, and molecular recognition  Academic Article
• Exploring the scope of the 29g12 antibody catalyzed 1,3-dipolar cycloaddition reaction  Academic Article
• Export of protein from the endoplasmic-reticulum is regulated by a diacylglycerol phorbol ester binding-protein  Academic Article
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• Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine d-1-like receptors in mice  Academic Article
• Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate  Academic Article
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• Expression and function of the cd3-antigen receptor on murine cd4+8+ thymocytes  Academic Article
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• Expression and purification of recombinant mouse fibrillarin  Academic Article
• Expression of 5-lipoxygenase and leukotriene a(4) hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability  Academic Article
• Expression of APP in brains of transgenic mice containing the entire human APP gene  Academic Article
• Expression of GABA(C) receptor rho 1 and rho 2 subunits during development of the mouse retina  Academic Article
• Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis  Academic Article
• Expression of a TNF inhibitor in transgenic mice  Academic Article
• Expression of a conserved cell-type-specific protein in nerve-terminals coincides with synaptogenesis  Academic Article
• Expression of a down-regulated target, ssecks, reverses v-jun-induced transformation of 10t1/2 murine fibroblasts  Academic Article
• Expression of a noncoding rna is elevated in alzheimer's disease and drives rapid feed-forward regulation of beta-secretase  Academic Article
• Expression of a sheep red blood-cell receptor by a murine lymphoma  Academic Article
• Expression of adenoviral e3 transgenes in beta cells prevents autoimmune diabetes  Academic Article
• Expression of alkaline-phosphatase from cloned human-tumor cell-lines in human mouse somatic-cell hybrids  Academic Article
• Expression of alpha v beta 3 and alpha v beta 8 integrins during oligodendrocyte precursor differentiation in the presence and absence of axons  Academic Article
• Expression of amino-terminally truncated prp in the mouse leading to ataxia and specific cerebellar lesions  Academic Article
• Expression of an adenovirally encoded lymphotoxin-beta inhibitor prevents clearance of Listeria monocytogenes in mice  Academic Article
• Expression of c-Fes protein isoforms correlates with differentiation in myeloid leukemias  Academic Article
• Expression of chicken liver-cell adhesion molecule fusion genes in transgenic mice  Academic Article
• Expression of cytotactin in the normal and regenerating neuromuscular system  Academic Article
• Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice  Academic Article
• Expression of fibrinolytic genes in tissues from human atherosclerotic aneurysms and from obese mice  Academic Article
• Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric antiganglioside gd2 antibody  Academic Article
• Expression of h-2 antigens during growth of cultured tumor cells  Academic Article
• Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice  Academic Article
• Expression of hepatitis B virus surface and core antigens: influences of pre-S and precore sequences  Academic Article
• Expression of human apolipoprotein b90 in transgenic mice - demonstration that apolipoprotein b90 laces the structural requirements to form lipoprotein(a)  Academic Article
• Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4b promotes assembly of enzyme subunits into an active dimer  Academic Article
• Expression of human platelet glycoprotein Ib alpha in transgenic mice  Academic Article
• Expression of leukemogenic recobinant viruses associated with a recessive gene in hrs-j mice  Academic Article
• Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage  Academic Article
• Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle  Academic Article
• Expression of raf family protooncogenes in normal mouse-tissues  Academic Article
• Expression of selected antigens on surface of cultured neural cells  Academic Article
• Expression of small cytoplasmic transcripts of the rat identifier element in vivo and in cultured cells  Academic Article
• Expression of t-cell receptor genes in an antigen-specific hybridoma and radiation-induced variants  Academic Article
• Expression of the hepatitis-delta virus large and small antigens in transgenic mice  Academic Article
• Expression of the lyst(beige) mutation is atheroprotective in chow-fed apolipoprotein e-deficient mice  Academic Article
• Expression of the tumor-necrosis-factor gene by dermal fibroblasts in response to ultraviolet-irradiation or lipopolysaccharide  Academic Article
• Expression of tie receptor tyrosine kinase in leukemia-cell lines  Academic Article
• Expression of tissue factor by melanoma-cells promotes efficient hematogenous metastasis  Academic Article
• Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with Borna disease virus  Academic Article
• Expression of transforming growth factor-beta and tumor necrosis factor-alpha in the plasma and tissues of mice with lupus nephritis  Academic Article
• Expression of truncated prp targeted to purkinje cells of prp knockout mice causes purkinje cell death and ataxia  Academic Article
• Expression of type 1 plasminogen activator inhibitor in renal tissue in murine lupus nephritis  Academic Article
• Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation  Academic Article
• Expression profiling identifies genes that continue to respond to insulin in adipocytes made insulin-resistant by treatment with tumor necrosis factor-alpha  Academic Article
• Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression  Academic Article
• Expression studies of catalytic antibodies  Academic Article
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• Extensive oxidative DNA-damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular-carcinoma  Academic Article
• Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the alpha 5 beta 1 integrin  Academic Article
• External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos  Academic Article
• Extinction of the tumor-necrosis-factor locus, and of genes encoding the lipopolysaccharide signaling pathway  Academic Article
• Extinction partially reverts structural changes associated with remote fear memory  Academic Article
• Extracellular matrix: Functions in the nervous system  Academic Article
• Extracellular processing of peptide antigens that bind class I major histocompatibility molecules  Academic Article
• Extracellular signal regulated kinase 5 (erk5) is required for the differentiation of muscle cells  Academic Article
• Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways  Academic Article
• Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways  Academic Article
• Extraction and partial purification of the histamine-sensitizing factor of Bordetella pertussis  Academic Article
• Extrahepatic expression and regulation of protein C in the mouse  Academic Article
• Extralymphatic virus sanctuaries as a consequence of potent T-cell activation  Academic Article
• Extraneural manifestations of prion infection in gpi-anchorless transgenic mice  Academic Article
• F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis  Academic Article
• F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen  Academic Article
• FAAH genetic variation enhances fronto-amygdala function in mouse and human  Academic Article
• FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration  Academic Article
• FAN stimulates TNFα-induced gene expression, leukocyte recruitment, and humoral response  Academic Article
• FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles  Academic Article
• FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development  Academic Article
• FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy  Academic Article
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• FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development  Academic Article
• FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas  Academic Article
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• FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination  Academic Article
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• Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation  Academic Article
• Factor xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1  Academic Article
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• Fat cells directly sense temperature to activate thermogenesis  Academic Article
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• Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice  Academic Article
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• Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens  Academic Article
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• Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes  Academic Article
• Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes  Academic Article
• Genetic loss of FAAH compromises male fertility in mice  Academic Article
• Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling  Academic Article
• Genetic modulation of T cell receptor gene segment usage during somatic recombination  Academic Article
• Genetic reassortants of lymphocytic choriomeningitis virus - unexpected disease and mechanism of pathogenesis  Academic Article
• Genetic regulation of behavioral and neuronal responses to fluoxetine  Academic Article
• Genetic regulation of commitment to interleukin 4 production by a cd4(+) t cell-intrinsic mechanism  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). I. H-2 restriction of the murine humoral immune response to the a and d determinants of HBsAg  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). II. Qualitative characteristics of the humoral immune response to the a, d, and y determinants of HBsAg  Academic Article
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• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). VI. T cell fine specificity  Academic Article
• Genetic reprogramming of tumor cells by zinc finger transcription factors  Academic Article
• Genetic risk prediction and neurobiological understanding of alcoholism  Academic Article
• Genetic studies in systemic autoimmunity and aging  Academic Article
• Genetic studies of auto-immunity and retrovirus expression in crosses of new-zealand black mice .2. Viral envelope glycoprotein gp70  Academic Article
• Genetic susceptibility to silver-induced anti-fibrillarin autoantibodies in mice  Academic Article
• Genetic-control of immunoglobulin-synthesis  Academic Article
• Genetic-regulation of the immune-response to hepatitis-b surface-antigen (hbsag) .5. T-cell proliferative response and cellular interactions  Academic Article
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• Genetics of SLE in mice  Academic Article
• Genetics of systemic autoimmunity and glomerulonephritis in mouse models of lupus  Academic Article
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• Genome-wide gain-of-function screen identifies novel regulators of pluripotency  Academic Article
• Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intake  Academic Article
• Genome-wide gene expression profiles of the developing mouse hippocampus  Academic Article
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• Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse  Academic Article
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• Genomic and biological variation among commonly used lymphocytic choriomeningitis virus-strains  Academic Article
• Genomic characterization of the lysophosphatidic acid receptor gene, lPA2/Edg4, and identification of a frameshift mutation in a previously characterized cDNA  Academic Article
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• Genomic organization and sequence of t-cell receptor beta-chain constant-region and joining-region genes  Academic Article
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• Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis  Academic Article
• Imidazolopiperazines: Hit to lead optimization of new antimalarial agents  Academic Article
• Imidazolopiperazines: Lead optimization of the second-generation antimalarial agents  Academic Article
• Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models  Academic Article
• Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form  Academic Article
• Immortalized clones of fibroblastic reticular cells activate virus-specific t cells during virus infection  Academic Article
• Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection  Academic Article
• Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes  Academic Article
• Immune complex disease in experimental animals and man  Academic Article
• Immune effectors required for hepatitis B virus clearance  Academic Article
• Immune pathogenesis of hepatocellular carcinoma  Academic Article
• Immune regulation by the st6gal sialyltransferase  Academic Article
• Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis  Academic Article
• Immune response of mice, rabbits and cattle to inactivated Mycoplasma mycoides subspecies Mycoides vaccines containing adjuvants  Academic Article
• Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization  Academic Article
• Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus  Academic Article
• Immune system-dependent and -independent replication of the scrapie agent  Academic Article
• Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10  Academic Article
• Immune tolerance split between hepatitis B virus precore and core proteins  Academic Article
• Immune versus natural selection: Antibody aldolases with enzymic rates but broader scope  Academic Article
• Immune-complexes can trigger specific, t-cell-dependent, autoanti-igg antibody-production in mice  Academic Article
• Immune-complexes in cancer - demonstration of complexes in mice bearing neuroblastomas  Academic Article
• Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice  Academic Article
• Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes  Academic Article
• Immunization of hu-pbl-scid mice and the rescue of human monoclonal fab fragments through combinatorial libraries  Academic Article
• Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity  Academic Article
• Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune responses in mice and woodchucks  Academic Article
• Immunobiology and pathogenesis of hepatocellular injury in hepatitis-B virus transgenic mice  Academic Article
• Immunobiology of Epstein-Barr virus-associated lymphomas  Academic Article
• Immunobiology of the autoantibody response. I. Circulating analogues of erythrocyte autoantigens and heterogeneity of the autoimmune response of NZB mice  Academic Article
• Immunobiology of the autoantibody response. II. The lipoprotein-associated soluble HB erythrocyte autoantigen of NZB mice  Academic Article
• Immunochemical characterization of human-tumor antigens  Academic Article
• Immunochemical heterogeneity of human-plasma high-density lipoproteins - identification with apolipoprotein a-i-specific and a-ii-specific monoclonal-antibodies  Academic Article
• Immunochemical termination of self-tolerance  Academic Article
• Immunochemistry of the dominating antigenic region ala582 to cys604 in the transmembranous protein of simian and human immunodeficiency virus  Academic Article
• Immunocytochemical demonstration of neural cell-adhesion molecule (ncam) along the migration route of luteinizing-hormone-releasing hormone (lhrh) neurons in mice  Academic Article
• Immunocytokines: A new approach to immunotherapy of melanoma  Academic Article
• Immunocytokines: A promising approach to cancer immunotherapy  Academic Article
• Immunodeficient mice xenografted with human lymphoid cells: new models for in vivo studies of human immunobiology and infectious diseases  Academic Article
• Immunodetection of cell-bound antigens using both mouse and human monoclonal-antibodies  Academic Article
• Immunodominance in virus-induced cd8(+) t-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon  Academic Article
• Immunoelectronmicroscopy of neural antigens on ultrathin frozen-sections  Academic Article
• Immunogenic peptides corresponding to the dominant antigenic region alanine-597 to cysteine-619 in the transmembrane protein of simian immunodeficiency virus have a propensity to fold in aqueous solution  Academic Article
• Immunogenic stability of heat-killed Mycoplasma mycoides subsp. Mycoides at 4 degrees C  Academic Article
• Immunogenicity and partial-purification of soluble h-2 antigens extracted with hypertonic salt  Academic Article
• Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: Implications for immunotherapy of persistent viral infections  Academic Article
• Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: Identification of an H2-Kd-restricted CTL epitope  Academic Article
• Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines  Academic Article
• Immunoglobulin gene rearrangement in b-cell deficient mice generated by targeted deletion of the j(h) locus  Academic Article
• Immunoglobulin-g - functional sites  Academic Article
• Immunoglobulin-kappa light chain variable region gene-complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice  Academic Article
• Immunoglobulins can utilize riboflavin (vitamin b2) to activate the antibody-catalyzed water oxidation pathway  Academic Article
• Immunohistochemical analysis of the development of somatostatin in the reeler neocortex  Academic Article
• Immunologic and biochemical properties of the histamine-sensitizing factor from Bordetella pertussis  Academic Article
• Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris  Academic Article
• Immunologic effects of an orally available BRAFV600E inhibitor in BRAF wild-type murine models  Academic Article
• Immunological and pathological consequences of coxsackievirus RNA persistence in the heart  Academic Article
• Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies  Academic Article
• Immunological basis of resistance to RL-male-1 induced by immunoselected Thy-1.2 negative variants  Academic Article
• Immunological detection of thymidine photoproduct formation in vivo  Academic Article
• Immunological disease induced by injecting F1 lymphoid cells into certain parental strains  Academic Article
• Immunological effects of neonatal infection with mouse thymic virus  Academic Article
• Immunological functions of lymphocytes fractionated with antigen-derivatized fibers  Academic Article
• Immunological relation of basement membrane and a serum beta globulin in the mouse. Demonstration of renal basement membrane alteration in mice injected with streptolysin S  Academic Article
• Immunological tumor destruction in a murine melanoma model by targeted lt alpha independent of secondary lymphoid tissue  Academic Article
• Immunology of muscarinic acetylcholine and beta-adrenergic catecholamine receptors  Academic Article
• Immunology: Toll-like receptors and antibody responses  Academic Article
• Immunomodulation and the quorum sensing molecule 3-oxo-C-12-homoserine lactone: The importance of chemical scaffolding for probe development  Academic Article
• Immunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation  Academic Article
• Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling  Academic Article
• Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (balb-c times nzb)f1 mice by scripps leukemia virus  Academic Article
• Immunopathology and pathogenesis of cutaneous involvement in systemic lupus erythematosus  Academic Article
• Immunopathology of adoptive immunization in mice chronically infected with lymphocytic choriomeningitis virus  Academic Article
• Immunopharmacotherapeutic manifolds and modulation of cocaine overdose  Academic Article
• Immunoproteasome-deficient mice mount largely normal cd8(+) t cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination  Academic Article
• Immunoselection of structural H-2Kb variants: use of cloned cytolytic T cells to select for loss of a CTL-defined allodeterminant  Academic Article
• Immunostimulatory DNA sequences necessary for effective intradermal gene immunization  Academic Article
• Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase  Academic Article
• Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells  Academic Article
• Immunosuppressive and autoimmune effects of thimerosal in mice  Academic Article
• Immunosuppressive effects of 3-methylcholanthrene given intratracheally in various inbred strains of mice  Academic Article
• Immunosuppressive effects of glucosamine  Academic Article
• Immunosuppressive effects of subglutinol derivatives  Academic Article
• Immunosurveillance of the liver by intravascular effector CD8(+) T cells  Academic Article
• Immunotherapy for virus-infection  Academic Article
• Immunotherapy of a murine colon cancer with syngeneic spleen-cells, immune rna and tumor-antigen  Academic Article
• Immunotherapy with a posttranscriptionally modified DNA vaccine induces complete protection against metastatic neuroblastoma  Academic Article
• Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells  Academic Article
• Impact of C4'-O-alkyl linker on in vivo pharmacokinetics of near-infrared cyanine/monoclonal antibody conjugates  Academic Article
• Impact of distinct chemical structures for the development of a methamphetamine vaccine  Academic Article
• Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice  Academic Article
• Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function  Academic Article
• Impact of sleep and circadian disruption on energy balance and diabetes: a summary of workshop discussions  Academic Article
• Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself  Academic Article
• Impact of substituents in tumor uptake and fluorescence imaging ability of near-infrared cyanine-like dyes  Academic Article
• Impact of sugar stereochemistry on natural killer T cell stimulation by bacterial glycolipids  Academic Article
• Impact of β2 integrin deficiency on mouse natural killer cell development and function  Academic Article
• Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein  Academic Article
• Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice  Academic Article
• Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome  Academic Article
• Impaired immunoproteasome assembly and immune responses in pa28(-/-) mice  Academic Article
• Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice  Academic Article
• Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain  Academic Article
• Impaired lymphopoiesis and altered b cell subpopulations in mice overexpressing lnk adaptor protein  Academic Article
• Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system  Academic Article
• Impaired microrna processing causes corpus luteum insufficiency and infertility in mice  Academic Article
• Impaired negative regulation of homeostatically proliferating T cells  Academic Article
• Impaired prion replication in spleens of mice lacking functional follicular dendritic cells  Academic Article
• Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin  Academic Article
• Impaired water maze learning performance in mu-opioid receptor knockout mice  Academic Article
• Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis  Academic Article
• Impairment of dopaminergic system function after chronic treatment with corticotropin-releasing factor  Academic Article
• Impairment of spatial but not contextual memory in camkii mutant mice with a selective loss of hippocampal ltp in the range of the theta-frequency  Academic Article
• Importance of cellular microenvironment and circulatory dynamics in b cell immunotherapy  Academic Article
• Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection  Academic Article
• Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers  Academic Article
• Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant  Academic Article
• Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist  Academic Article
• In a transgenic model of spontaneous autoimmune diabetes, expression of a protective class II MHC molecule results in thymic deletion of diabetogenic CD8+ T cells  Academic Article
• In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages  Academic Article
• In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness  Academic Article
• In silico qtl mapping of basal liver iron levels in inbred mouse strains  Academic Article
• In situ click chemistry: Enzyme inhibitors made to their own specifications  Academic Article
• In situ cytokine therapy: Redistribution of clonally expanded t cells  Academic Article
• In situ measurement of solute transport in the bone lacunar-canalicular system  Academic Article
• In situ selection of lead compounds by click chemistry: Target-guided optimization of acetylcholinesterase inhibitors  Academic Article
• In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics  Academic Article
• In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the alpha 6 beta 4 integrin and dystroglycan  Academic Article
• In vitro and in vivo anticancer activity of a synthetic glycolipid as Toll-like receptor 4 (TLR4) activator  Academic Article
• In vitro and in vivo neurotoxicity of prion protein oligomers  Academic Article
• In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi  Academic Article
• In vitro construction of a b-tropic virus by recombination - b-tropism is a cryptic phenotype of xenotropic murine retroviruses  Academic Article
• In vitro dendritic cell infection by pseudotyped adenoviral vectors does not correlate with their in vivo immunogenicity  Academic Article
• In vitro detection of cells infected with lactic dehydrogenase virus (LDV) by fluorescein-labeled antibody to LDV  Academic Article
• In vitro drug testing using hemopoietic cells: goals and limitations  Academic Article
• In vitro functional-characterization of sag-3 - a naturally-occurring monoclonal-antibody in nzb mice - specificity toward functional t-cell subsets  Academic Article
• In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots  Academic Article
• In vitro responses of CBA/N mice: spleen cells of mice with an X-linked defect that precludes immune responses to several thymus-independent antigens can respond to TNP-lipopolysaccharide  Academic Article
• In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library  Academic Article
• In vitro studies of the genetically determined unresponsiveness to thymus-independent antigens in CBA/N mice  Academic Article
• In vitro transformation of murine bone marrow cells with a v-raf/v-myc retrovirus yields clonally related mature b cells and macrophages  Academic Article
• In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses  Academic Article
• In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation  Academic Article
• In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire  Academic Article
• In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease  Academic Article
• In vivo accumulation of t cells in response to il-2/anti-il-2 mab complexes is dependent in part on the tnf family ligand 4-1bbl  Academic Article
• In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, mk-826 (l-749,345)  Academic Article
• In vivo activity in a catalytic antibody-prodrug system: antibody catalyzed etoposide prodrug activation for selective chemotherapy  Academic Article
• In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance  Academic Article
• In vivo and in vitro production of anti-histone antibodies in NZB/NZW mice  Academic Article
• In vivo and in vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker  Academic Article
• In vivo anergized T cells form altered immunological synapses in vitro  Academic Article
• In vivo brain GPCR signaling elucidated by phosphoproteomics  Academic Article
• In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons  Academic Article
• In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects  Academic Article
• In vivo cleavage of alpha 2,6-sialyltransferase by alzheimer beta-secretase  Academic Article
• In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated beta1 integrin and induction of FAK/PI3K/Akt motility signaling  Academic Article
• In vivo complementation of complex i by the yeast ndi1 enzyme - possible application for treatment of parkinson disease  Academic Article
• In vivo conversion of bm plasmacytoid dc into cd11b(+) conventional dc during virus infection  Academic Article
• In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides  Academic Article
• In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I  Academic Article
• In vivo efficacy of natural product-inspired irreversible kinase inhibitors  Academic Article
• In vivo efficacy of novel synthetic enediynes 1  Academic Article
• In vivo expansion of t reg cells with il-2-mab complexes: Induction of resistance to eae and long-term acceptance of islet allografts without immunosuppression  Academic Article
• In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes  Academic Article
• In vivo expression of human growth hormone by genetically modified murine bone marrow stromal cells and its effect on the cells in vitro  Academic Article
• In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection  Academic Article
• In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers  Academic Article
• In vivo imaging of hepcidin promoter stimulation by iron and inflammation  Academic Article
• In vivo interrogation of the molecular display of atherosclerotic lesion surfaces  Academic Article
• In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function  Academic Article
• In vivo osteopontin-induced macrophage accumulation is dependent on CD44 expression  Academic Article
• In vivo potent BM635 analogue with improved drug-like properties  Academic Article
• In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models  Academic Article
• In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation  Academic Article
• In vivo regulation of crkii and crkl proto-oncogenes in the uterus by insulin-like growth factor-i - differential effects on tyrosine phosphorylation and association with paxillin  Academic Article
• In vivo regulation of hepatitis B virus replication by peroxisome proliferators  Academic Article
• In vivo relevance for platelet glycoprotein Ib alpha residue Tyr276 in thrombus formation  Academic Article
• In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice  Academic Article
• In vivo selection for metastasis promoting genes in the mouse  Academic Article
• In vivo stabilization of mutant human transthyretin in transgenic mice  Academic Article
• In vivo suppression of the primary immune response by a species of low density serum lipoprotein  Academic Article
• In vivo targeting of b-cell lymphoma with glycan ligands of cd22  Academic Article
• In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors  Academic Article
• In vivo treatment with a mhc class i-restricted blocking peptide can prevent virus-induced autoimmune diabetes  Academic Article
• In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line  Academic Article
• In vivo-activated cd4 t cells upregulate cxc chemokine receptor 5 and reprogram their response to lymphoid chemokines  Academic Article
• In-frame TCR delta-gene rearrangements play a critical role in the alpha-beta/gamma-delta T-cell lineage decision  Academic Article
• Inability of il-2 and il-10 to counteract b-cell clonal deletion  Academic Article
• Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers  Academic Article
• Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging  Academic Article
• Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids  Academic Article
• Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1  Academic Article
• Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1  Academic Article
• Inactivation of macrophage nitric oxide synthase activity by ng-methyl-l-arginine  Academic Article
• Inactivation of pkc theta leads to increased susceptibility to obesity and dietary insulin resistance in mice  Academic Article
• Inactivation of the 5-ht7 receptor partially blocks phencyclidine-induced disruption of prepulse inhibition  Academic Article
• Inactivation of the p53 pathway in retinoblastoma  Academic Article
• Inactivation of thiol-dependent enzymes by hypothiocyanous acid: Role of sulfenyl thiocyanate and sulfenic acid intermediates  Academic Article
• Incomplete T-cell receptor V-beta allelic exclusion and dual V-beta-expressing cells  Academic Article
• Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: Generation of antibodies against the thrombin-sensitive region of murine protein S  Academic Article
• Incorporation of phosphonate into benzonaphthyridine toll-like receptor 7 agonists for adsorption to aluminum hydroxide  Academic Article
• Incorporation of the purified epstein-barr virus/c3d receptor (cr-2) into liposomes and demonstration of its dual ligand-binding functions  Academic Article
• Increase of anti-metastatic efficacy by selectivity-but not affinity-optimization of synthetic serine protease inhibitors  Academic Article
• Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal  Academic Article
• Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A  Academic Article
• Increased c-fos expression in the central nucleus of the amygdala and enhancement of cued fear memory in dyt1 delta gag knock-in mice  Academic Article
• Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)  Academic Article
• Increased endothelial expression of toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events  Academic Article
• Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice  Academic Article
• Increased ethanol self-administration in delta-opioid receptor knockout mice  Academic Article
• Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies  Academic Article
• Increased expression of fibronectin and the alpha 5 beta 1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia  Academic Article
• Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction  Academic Article
• Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "klotho" mouse  Academic Article
• Increased expression of the beta 4 and alpha 5 integrin subunits in cerebral blood vessels of transgenic mice chronically producing the pro-inflammatory cytokines il-6 or ifn-alpha, in the central nervous system  Academic Article
• Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice  Academic Article
• Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance  Academic Article
• Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice  Academic Article
• Increased immune response variability during simultaneous viral coinfection leads to unpredictability in CD8 T cell immunity and pathogenesis  Academic Article
• Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta(-/-) mice  Academic Article
• Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7α-hydroxylase  Academic Article
• Increased response to morphine in mice lacking protein kinase c epsilon  Academic Article
• Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase  Academic Article
• Increased spectrin proteolysis in the brindled mouse-brain  Academic Article
• Increased survival and reduced neutrophil infiltration of the liver in Rab27a-but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation  Academic Article
• Increased survival times of new-zealand hybrid mice immunosuppressed by graft versus host reactions  Academic Article
• Increased susceptibility to DNA virus infection in mice with a GCN2 mutation  Academic Article
• Increased thrombogenesis and embolus formation in mice lacking glycoprotein V  Academic Article
• Increased yield of antibody-producing murine spleen-cell hybridomas from fusions cultured in medium supplemented with mouse serum  Academic Article
• Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation  Academic Article
• Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia  Academic Article
• Increasing t-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex - mismatched bone marrow transplant model  Academic Article
• Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality  Academic Article
• Increasing the chemical potential of the germ-line antibody repertoire  Academic Article
• Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of EphB2 and neuronal activity  Academic Article
• Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization  Academic Article
• Individual V-H promoters vary in strength, but the frequency of rearrangement of those V-H genes does not correlate with promoter strength nor enhancer-independence  Academic Article
• Individually programmable cell stretching microwell arrays actuated by a Braille display  Academic Article
• Indoleamine 2,3-dioxygenase expression in trans-planted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes  Academic Article
• Induced pluripotent stem cells free of exogenous reprogramming factors  Academic Article
• Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses  Academic Article
• Inducible and reversible gene expression with the rtta system for the study of memory  Academic Article
• Inducible control of gene expression with destabilized Cre  Academic Article
• Inducible expression of the long pentraxin PTX3 in the central nervous system  Academic Article
• Inducible gene expression in mammalian cells and transgenic mice  Academic Article
• Inducible nitric oxide synthase: Role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction  Academic Article
• Induction and rapid expression of an immune response in vitro  Academic Article
• Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules  Academic Article
• Induction of B cell priming by neonatal injection of mice with thymic-independent (type 2) antigens  Academic Article
• Induction of B lymphocyte proliferation by monoclonal anti-Lyb 2 antibody  Academic Article
• Induction of CD44 expression by the Epstein-Barr virus latent membrane protein LMP1 is associated with lymphoma dissemination  Academic Article
• Induction of a pharmacologically active clonotypic b-cell response directed to an immunogenic region of the human beta-2-adrenergic receptor  Academic Article
• Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins  Academic Article
• Induction of an antibody that catalyzes the hydrolysis of an amide bond  Academic Article
• Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12  Academic Article
• Induction of antiviral antibodies by DNA immunization requires neither perforin-mediated nor cd8(+)-t-cell-mediated lysis of antigen-expressing cells  Academic Article
• Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded microRNA-15a  Academic Article
• Induction of c-fos mRNA in the arcuate nucleus of normal and mutant growth hormone-deficient mice by a synthetic non-peptidyl growth hormone secretagogue  Academic Article
• Induction of c-fos messenger-rna and ap-1 DNA-binding activity by camp in cooperation with either the adenovirus 243-amino or the adenovirus 289-amino acid e1a protein  Academic Article
• Induction of hematopoietic microenvironment by the extracellular matrix from long-term bone marrow cultures  Academic Article
• Induction of high serum levels of retroviral env gene-products (gp70) in mice by bacterial lipopolysaccharide  Academic Article
• Induction of igg antibodies by an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
• Induction of interferon-gamma inducing factor in the adrenal cortex  Academic Article
• Induction of minor alloantigen-specific T cell subsets in vivo: recognition of processed antigen by helper but not by cytotoxic T cell precursors  Academic Article
• Induction of monocyte procoagulant activity by murine hepatitis-virus type-3 parallels disease susceptibility in mice  Academic Article
• Induction of murine autoimmune-disease by chronic polyclonal b-cell activation  Academic Article
• Induction of nitrite/nitrate synthesis in murine macrophages by bcg infection, lymphokines, or interferon-gamma  Academic Article
• Induction of ornithine decarboxylase by il-3 is mediated by sequential c-myc-independent and c-myc-dependent pathways  Academic Article
• Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3  Academic Article
• Induction of persistent tumor-protective immunity in mice cured of established colon carcinoma metastases  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in adipocytes by thiazolidinediones  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha  Academic Article
• Induction of pluripotency in mouse somatic cells with lineage specifiers  Academic Article
• Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds  Academic Article
• Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2  Academic Article
• Induction of pregnancy during established EAE halts progression of CNS autoimmune injury via pregnancy-specific serum factors  Academic Article
• Induction of retinal progenitors and neurons from mammalian Müller glia under defined conditions  Academic Article
• Induction of rheumatoid antibodies in the mouse - regulated production of autoantibody in the secondary humoral response  Academic Article
• Induction of severe autoimmune-disease in normal mice by simultaneous action of multiple immunostimulators  Academic Article
• Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice  Academic Article
• Induction of systemic autoimmunity by a xenobiotic requires endosomal TLR trafficking and signaling from the late endosome and endolysosome but not type I IFN  Academic Article
• Induction of the early growth response (Egr) family of transcription factors during thymic selection  Academic Article
• Induction of transcription factor ap-1 by adenovirus e1a-protein and camp  Academic Article
• Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice  Academic Article
• Induction of type-i interferon genes and interferon-inducible genes in embryonal stem-cells devoid of interferon regulatory factor-i  Academic Article
• Infected cd8 alpha(-) dendritic cells are the predominant source of il-10 during establishment of persistent viral infection  Academic Article
• Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice  Academic Article
• Infection control by antibody disruption of bacterial quorum sensing signaling  Academic Article
• Infection of lymphocytes by a virus that aborts cytotoxic lymphocyte-t activity and establishes persistent infection  Academic Article
• Infection with a recombinant vaccinia virus encoding myelin proteolipid protein causes suppression of chronic relapsing-remitting experimental allergic encephalomyelitis  Academic Article
• Infection with vaccinia favors the selection of hybridomas synthesizing autoantibodies against intermediate filaments, one of them cross-reacting with the virus hemagglutinin  Academic Article
• Infectious rna isolated from the spinal cords of mice chronically infected with theiler's murine encephalomyelitis virus  Academic Article
• Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA  Academic Article
• Infectivity of scrapie prions bound to a stainless steel surface  Academic Article
• Inflammasome activation by cystine crystals: implications for the pathogenesis of cystinosis  Academic Article
• Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity  Academic Article
• Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger  Academic Article
• Inflammation in atherosclerosis - lesion formation in ldl receptor-deficient mice with perforin and lyst(beige) mutations  Academic Article
• Inflammation, obesity, and thrombosis  Academic Article
• Inflammatory cells in solid murine neoplasms. I. Tumor disaggregation and identification of constituent inflammatory cells  Academic Article
• Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression  Academic Article
• Inflammatory cytokines: Putative regulators of neuronal and neuro-endocrine function  Academic Article
• Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice  Academic Article
• Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer  Academic Article
• Influence of antigen on a model for analysis of multiple coordinate events associated with the primary immune-response  Academic Article
• Influence of coding-end sequence on coding-end processing in V(D)J recombination  Academic Article
• Influence of the N-terminal domain on the aggregation properties of the prion protein  Academic Article
• Influence of the immunoregulatory serum lipoprotein LDL-In on the in vivo proliferation and differentiation of antigen-binding and antibody-secreting lymphocytes during a primary immune response  Academic Article
• Influence of the major histocompatibility complex on the repertoire of allospecific cytolytic T lymphocytes  Academic Article
• Influence of threonine metabolism on S-adenosylmethionine and histone methylation  Academic Article
• Influence of thymic genotype on the systemic lupus erythematosus-like disease and t-cell proliferation of mrl-mp-lpr-lpr mice  Academic Article
• Influencing uptake and localization of aminoglycoside-functionalized peptoids  Academic Article
• Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I  Academic Article
• Influenza virus-like particles engineered by protein transfer with tumor-associated antigens induces protective antitumor immunity  Academic Article
• Influenza virus-susceptible mice carry mx-genes with a large deletion or a nonsense mutation  Academic Article
• Infrared fluorescence for vascular barrier breach in vivo - a novel method for quantitation of albumin efflux  Academic Article
• Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice  Academic Article
• Inhibiting oxidative phosphorylation in vivo restrains Th17 effector responses and ameliorates murine colitis  Academic Article
• Inhibiting scrapie neuroinvasion by polyene antibiotic treatment of SCID mice  Academic Article
• Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors  Academic Article
• Inhibition by colchicine of mitogenic stimulation of lymphocytes prior to s-phase  Academic Article
• Inhibition by dexamethasone of beta-3-adrenergic receptor responsiveness in 3t3-f442a adipocytes - evidence for a transcriptional mechanism  Academic Article
• Inhibition by ginsenosides rb-1 and rg(1) of methamphetamine-induced hyperactivity, conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice  Academic Article
• Inhibition by mk-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice  Academic Article
• Inhibition by mk-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice  Academic Article
• Inhibition by noncompetitive nmda receptor antagonists of apomorphine-induced climbing behavior in mice  Academic Article
• Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice  Academic Article
• Inhibition of BMK1 pathway suppresses cancer stem cells through BNIP3 and BNIP3L  Academic Article
• Inhibition of Dpp8/9 activates the Nlrp1b inflammasome  Academic Article
• Inhibition of Epstein-Barr virus infection in vitro and in vivo by soluble CR2 (CD21) containing two short consensus repeats  Academic Article
• Inhibition of HIV ENV binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120  Academic Article
• Inhibition of NF-kappa B in cancer cells converts inflammation-induced tumor growth mediated by TNF alpha to TRAIL-mediated tumor regression  Academic Article
• Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes  Academic Article
• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation  Academic Article
• Inhibition of S-adenosyl-L-homocysteine hydrolase induces immunosuppression  Academic Article
• Inhibition of Ubc13-mediated ubiquitination by GPS2 regulates multiple stages of B cell development  Academic Article
• Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models  Academic Article
• Inhibition of alpha(v)beta(3) integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy  Academic Article
• Inhibition of antibodies to nuclear antigen and to DNA in new zealand mice infected with lactate dehydrogenase virus  Academic Article
• Inhibition of antibody-production at high cell-density following mitogen stimulation and isotype switching in vitro  Academic Article
• Inhibition of astrocyte glutamate uptake by reactive oxygen species: Role of antioxidant enzymes  Academic Article
• Inhibition of baclofen on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity  Academic Article
• Inhibition of cancer cell proliferation by designed peptide amphiphiles  Academic Article
• Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway  Academic Article
• Inhibition of circulating dipeptidyl peptidase 4 activity in patients with metastatic prostate cancer  Academic Article
• Inhibition of class i histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue  Academic Article
• Inhibition of dynorphin-converting enzymes prolongs the antinociceptive effect of intrathecally administered dynorphin in the mouse formalin test  Academic Article
• Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay  Academic Article
• Inhibition of endogenous leptin protects mice from arterial and venous thrombosis  Academic Article
• Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4  Academic Article
• Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task  Academic Article
• Inhibition of hepatitis B virus in mice by RNA interference  Academic Article
• Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice  Academic Article
• Inhibition of hepatitis B virus replication during schistosoma mansoni infection in transgenic mice  Academic Article
• Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts  Academic Article
• Inhibition of immunological injury of cultured-cells infected with lymphocytic choriomeningitis virus - role of defective interfering virus in regulating viral antigenic expression  Academic Article
• Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice  Academic Article
• Inhibition of lipopolysaccharide activation of 70z/3 cells by anti-lipopolysaccharide antibodies  Academic Article
• Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor  Academic Article
• Inhibition of matrix metalloproteinase 9 activation by a specific monoclonal antibody  Academic Article
• Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway  Academic Article
• Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice  Academic Article
• Inhibition of monoacylglycerol lipase reduces nicotine withdrawal  Academic Article
• Inhibition of mutation and combating the evolution of antibiotic resistance  Academic Article
• Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance  Academic Article
• Inhibition of sonic hedgehog autoprocessing in cultured mammalian cells by sterol deprivation  Academic Article
• Inhibition of srgap2 function by its human-specific paralogs induces neoteny during spine maturation  Academic Article
• Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate  Academic Article
• Inhibition of t-cell proliferation and sle-like syndrome of mrl-1 mice by whole-body or total lymphoid irradiation  Academic Article
• Inhibition of the IKK/NF-kappa B pathway by AAV gene transfer improves muscle regeneration in older mdx mice  Academic Article
• Inhibition of tissue factor signaling suppresses tumor growth  Academic Article
• Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor  Academic Article
• Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system  Academic Article
• Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1  Academic Article
• Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes  Academic Article
• Inhibitor kappa b and nuclear factor kappa b in granulocyte-macrophage colony-stimulating factor antagonism of dexamethasone suppression of the macrophage response to aspergillus fumigatus conidia  Academic Article
• Inhibitor of MYC identified in a Krohnke pyridine library  Academic Article
• Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects  Academic Article
• Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease  Academic Article
• Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice  Academic Article
• Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice  Academic Article
• Inhibitory effects of mk-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine  Academic Article
• Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling  Academic Article
• Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome  Academic Article
• Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacy  Academic Article
• Ink4c is dispensable for tumor suppression in myc-induced b-cell lymphomagenesis  Academic Article
• Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism  Academic Article
• Innate differences of neuropeptide Y (NPY) in hypothalamic nuclei and central nucleus of the amygdala between selectively bred rats with high and low alcohol preference  Academic Article
• Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity  Academic Article
• Inorganic pyrophosphatase induces type I collagen in osteoblasts  Academic Article
• Inositol (1,4,5) trisphosphate 3 kinase b controls positive selection of t cells and modulates erk activity  Academic Article
• Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling  Academic Article
• Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways  Academic Article
• Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain  Academic Article
• Inositol pyrophosphates pyrotechnics  Academic Article
• Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling  Academic Article
• Input-specific regulation of hippocampal circuit maturation by non-muscle myosin IIB  Academic Article
• Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties  Academic Article
• Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9 Å resolution  Academic Article
• Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation  Academic Article
• Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance  Academic Article
• Instant immunity through chemically programmable vaccination and covalent self-assembly  Academic Article
• Insulin biosynthetic interaction network component, TMEM24, facilitates insulin reserve pool release  Academic Article
• Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons  Academic Article
• Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes  Academic Article
• Insulin in oral immune "tolerance": A one-amino acid change in the b chain makes the difference  Academic Article
• Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2  Academic Article
• Insulin receptor substrate protein p53 localization in rats suggests mechanism for specific polyglutamine neurodegeneration  Academic Article
• Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors  Academic Article
• Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells  Academic Article
• Insulinoma-released exosomes activate autoreactive marginal zone-like B cells that expand endogenously in prediabetic NOD mice  Academic Article
• Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice  Academic Article
• Integral membrane proteins of the nuclear envelope are dispersed throughout the endoplasmic reticulum during mitosis  Academic Article
• Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome  Academic Article
• Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes  Academic Article
• Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice  Academic Article
• Integrated regulation of toll-like receptor responses by notch and interferon-gamma pathways  Academic Article
• Integration of cardiac proteome biology and medicine by a specialized knowledgebase  Academic Article
• Integration of deoxyribonucleic acid specific for rous-sarcoma virus after infection of permissive and nonpermissive hosts  Academic Article
• Integration of the genetic map and genome assembly of fugu facilitates insights into distinct features of genome evolution in teleosts and mammals  Academic Article
• Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity  Academic Article
• Integrative analysis of low- and high-resolution eqtl  Academic Article
• Integrative assessment of chlorine-induced acute lung injury in mice  Academic Article
• Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury  Academic Article
• Integrin activation controls metastasis in human breast cancer  Academic Article
• Integrin alpha 6a beta 1 induces cd81-dependent cell motility without engaging the extracellular matrix migration substrate  Academic Article
• Integrin alpha 8 beta 1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis  Academic Article
• Integrin requirement for hippocampal synaptic plasticity and spatial memory  Academic Article
• Integrin signaling switches the cytoskeletal and exocytic machinery that drives neuritogenesis  Academic Article
• Integrin α(v)β(3) targeted therapy for Kaposi's sarcoma with an in vitro evolved antibody  Academic Article
• Integrin α4β1 (VLA-4) expression and activity in retinal and peripheral neurons  Academic Article
• Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development  Academic Article
• Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage  Academic Article
• Integrins mediate a neuronal survival signal for oligodendrocytes  Academic Article
• Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis  Academic Article
• Interaction between Raf and Myc oncogenes in transformation in vivo and in vitro  Academic Article
• Interaction between a 54-kilodalton mammalian cell surface protein and cowpea mosaic virus  Academic Article
• Interaction between the corticotropin-releasing factor system and hypocretins (orexins): A novel circuit mediating stress response  Academic Article
• Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase  Academic Article
• Interaction of Cowpea mosaic virus (CPMV) nanoparticles with antigen presenting cells in vitro and in vivo  Academic Article
• Interaction of NADPH oxidase 1 with Toll-like receptor 2 induces migration of smooth muscle cells  Academic Article
• Interaction of calmodulin with the inducible murine macrophage nitric oxide synthase  Academic Article
• Interaction of cowpea mosaic virus nanoparticles with surface vimentin and inflammatory cells in atherosclerotic lesions  Academic Article
• Interaction of drug- and granulocyte-mediated killing of Pseudomonas aeruginosa in a murine pneumonia model  Academic Article
• Interaction of helper T cells and Lyb5+ B cells responding to phosphorylcholine is MHC-restricted  Academic Article
• Interaction of the N-terminal domain of the AMPA receptor GIuR4 subunit with the neuronal pentraxin NP1 mediates GluR4 synaptic recruitment  Academic Article
• Interaction of the peroxisome proliferator-activated receptor-alpha with the retinoid-X receptor-alpha unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter  Academic Article
• Interaction of the taz1 domain of the creb-binding protein with the activation domain of cited2 - regulation by competition between intrinsically unstructured ligands for non-identical binding sites  Academic Article
• Interactions between ICAM-5 and β1 integrins regulate neuronal synapse formation  Academic Article
• Interactions between enteroviruses and autophagy in vivo  Academic Article
• Interactions between viruses and lymphocytes. I. In vivo replication of lymphocytic choriomeningitis virus in mononuclear cells during both chronic and acute viral infections  Academic Article
• Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1  Academic Article
• Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia - Reperfusion injury  Academic Article
• Intercellular coupling confers robustness against mutations in the SCN circadian clock network  Academic Article
• Interendothelial claudin-5 expression depends on cerebral endothelial cell-matrix adhesion by beta(1)-integrins  Academic Article
• Interference with major histocompatibility complex class-ii-restricted antigen presentation in the brain by herpes-simplex virus type-1 - a possible mechanism of evasion of the immune-response  Academic Article
• Interfering with resistance to Smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma  Academic Article
• Interferon gamma receptor deficient mice are resistant to endotoxic shock  Academic Article
• Interferon modulation of cellular microRNAs as an antiviral mechanism  Academic Article
• Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids  Academic Article
• Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression  Academic Article
• Interferon-alpha gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models  Academic Article
• Interferon-gamma acts directly on cd8(+) t cells to increase their abundance during virus infection  Academic Article
• Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus  Academic Article
• Interferon-gamma is required for lupus-like disease and lymphoaccumulation in mrl-lpr mice  Academic Article
• Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of cxcl10/ip-10 gene expression by astrocytes in vivo and in vitro  Academic Article
• Interferon-induced transmembrane protein 3 is a type II transmembrane protein  Academic Article
• Interferon-production during lymphocytic choriomeningitis virus-infection of nude and normal mice  Academic Article
• Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice  Academic Article
• Interferon-γ production by peripheral lymphocytes predicts survival of tumor-bearing mice receiving dual PD-1/CTLA-4 blockade  Academic Article
• Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice  Academic Article
• Interleukin (il)-15 and il-7 jointly regulate homeostatic proliferation of memory phenotype cd8(+) cells but are not required for memory phenotype cd4(+) cells  Academic Article
• Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury  Academic Article
• Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype cd8(+) t cells  Academic Article
• Interleukin 18 activates MAPKs and STAT3 but not NF-kappa B in hippocampal HT-22 cells  Academic Article
• Interleukin 18 gene transfer expands the repertoire of antitumor Th1-type immunity elicited by dendritic cell-based vaccines in association with enhanced therapeutic efficacy  Academic Article
• Interleukin 7 regulates the survival and generation of memory cd4 cells  Academic Article
• Interleukin-1 beta and tumour necrosis factor-alpha stimulate the mRNA expression of interleukin-1 receptors in mouse anterior pituitary AtT-20 cells  Academic Article
• Interleukin-1 beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons  Academic Article
• Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor  Academic Article
• Interleukin-1 system in CNS stress: seizures, fever, and neurotrauma  Academic Article
• Interleukin-1-beta (IL-1-beta) processing in murine macrophages requires a structurally conserved homolog of human IL-1-beta converting enzyme  Academic Article
• Interleukin-1-induced NF-kappaB activation is nemo-dependent but does not require IKKbeta  Academic Article
• Interleukin-1-mediated febrile responses in mice and interleukin-1 beta activation lot NF kappa B in mouse primary astrocytes, involves the interleukin-1 receptor accessory protein  Academic Article
• Interleukin-10 determines viral clearance or persistence in vivo  Academic Article
• Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors  Academic Article
• Interleukin-12 inhibits hepatitis B virus replication in transgenic mice  Academic Article
• Interleukin-17 promotes angiogenesis and tumor growth  Academic Article
• Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency  Academic Article
• Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice  Academic Article
• Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment  Academic Article
• Interleukin-18 null mutation increases weight and food intake and reduces energy expenditure and lipid substrate utilization in high-fat diet fed mice  Academic Article
• Interleukin-1β contributes to the generation of experimental febrile seizures  Academic Article
• Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways  Academic Article
• Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells  Academic Article
• Interleukin-2 differentially regulates il-2 receptors on murine cloned cytolytic and helper t-cells  Academic Article
• Interleukin-2 down-regulates hepatitis-B virus gene-expression in transgenic mice by a posttranscriptional mechanism  Academic Article
• Interleukin-2/interleukin-2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation  Academic Article
• Interleukin-3 (il-3) induces transcription from nonrearranged t-cell receptor gamma loci in il-3-dependent cell-lines  Academic Article
• Interleukin-6 promotes systemic lupus erythematosus progression with Treg suppression approach in a murine systemic lupus erythematosus model  Academic Article
• Interleukin-6-induced plasminogen gene expression in murine hepatocytes is mediated by transcription factor CCAAT/enhancer binding protein beta (C/EBP beta)  Academic Article
• Interleukin-8 and its receptor cxcr2 in atherosclerosis  Academic Article
• Intermolecular interaction between anchoring subunits specify subcellular targeting and function of RGS proteins in retina ON-bipolar neurons  Academic Article
• Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells  Academic Article
• Interplay between cell-adhesion molecules governs synaptic wiring of cone photoreceptors  Academic Article
• Interrelating B cell subpopulations and environmental regulation with the expression of three tiers of repertoire diversity  Academic Article
• Interstitial immune-complex thyroiditis in mice - role of autoantibody to thyroglobulin  Academic Article
• Intervention of cd4(+) cell subset shifts and autoimmunity in the bxsb mouse by murine ctla4ig  Academic Article
• Intracellular hepatitis B virus nucleocapsids survive cytotoxic T-lymphocyte-induced apoptosis  Academic Article
• Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes  Academic Article
• Intracellular plasminogen activator activity in growing and quiescent cells  Academic Article
• Intracellular protein modification associated with altered T cell functions in autoimmunity  Academic Article
• Intracerebroventricular injection of amyloid-β peptides in normal mice to acutely induce alzheimer-like cognitive deficits  Academic Article
• Intragraft tnf receptor signaling contributes to activation of innate and adaptive immunity in a renal allograft model  Academic Article
• Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice  Academic Article
• Intralysosomal cystine accumulation in mice lacking cystinosin, the protein defective in cystinosis  Academic Article
• Intranasal delivery of erythropoietin plus insulin-like growth factor-I for acute neuroprotection in stroke  Academic Article
• Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice  Academic Article
• Intrathecal administration of p-hydroxymercuribenzoate or phosphoramidon/bestatin-combined induces antinociceptive effects through different opioid mechanisms  Academic Article
• Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an n-methyl-d-aspartate receptor mechanism  Academic Article
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• Intrathymic injection of polynucleosomes delays autoantibody production in bxsb mice  Academic Article
• Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity  Academic Article
• Intratumoral hu14.18-il-2 (ic) induces local and systemic antitumor effects that involve both activated t and nk cells as well as enhanced ic retention  Academic Article
• Intratumoral immunocytokine treatment results in enhanced antitumor effects  Academic Article
• Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the Hu14.18 antibody increases intratumoral CD8+T and NK cells and improves survival  Academic Article
• Intravenous administration of human embryonic stem cell-derived neural precursor cells attenuates cuprizone-induced central nervous system (cns) demyelination  Academic Article
• Intravenous nicotine self-administration and cue-induced reinstatement in mice: Effects of nicotine dose, rate of drug infusion and prior instrumental training  Academic Article
• Intravenous self-administration of heroin, cocaine, and the combination in balb/c mice  Academic Article
• Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury  Academic Article
• Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection  Academic Article
• Intrinsically photosensitive retinal ganglion cells (ipRGCs) are necessary for light entrainment of peripheral clocks  Academic Article
• Introduction of nucleophiles and spectroscopic probes into antibody combining sites  Academic Article
• Introduction to Cellular Immunology Special Issue on γδ T cells  Academic Article
• Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation  Academic Article
• Invariant natural killer t cells recognize glycolipids from pathogenic gram-positive bacteria  Academic Article
• Investigating hapten clustering as a strategy to enhance vaccines against drugs of abuse  Academic Article
• Investigating the role of DNA damage in tobacco smoking-induced spine degeneration  Academic Article
• Investigations of enantiopure nicotine haptens using an adjuvanting carrier in anti-nicotine vaccine development  Academic Article
• Involvement of 5-ht1a and gaba(a) receptors in the anxiolytic-like effects of cinnamomum cassia in mice  Academic Article
• Involvement of 5-ht3 receptors in the development and expression of methamphetamine-induced behavioral sensitization: 5-ht3a receptor channel and binding study  Academic Article
• Involvement of LPA1 receptor signaling in cerebral ischemia-induced neuropathic pain  Academic Article
• Involvement of LPA1 receptor signaling in the reorganization of spinal input through abeta-fibers in mice with partial sciatic nerve injury  Academic Article
• Involvement of b lymphocytes in the growth inhibition of human pulmonary melanoma metastases in athymic nu/nu mice by in antibody-lymphotoxin fusion protein  Academic Article
• Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons  Academic Article
• Involvement of integrins alpha(v)beta(3) and alpha(v)beta(5) in ocular neovascular diseases  Academic Article
• Involvement of mu-opioid receptors in potentiation of apomorphine-induced climbing behavior by morphine: Studies using mu-opioid receptor gene knockout mice  Academic Article
• Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice  Academic Article
• Involvement of the clock gene Rev-erb alpha in the regulation of glucagon secretion in pancreatic alpha-cells  Academic Article
• Involvement of the sigma(1) receptor in cocaine-induced conditioned place preference: Possible dependence on dopamine uptake blockade  Academic Article
• Involvement of the sigma(1) receptor in the cocaine-induced conditioned place preference  Academic Article
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• Is the TAM receptor Axl a receptor for lymphocytic choriomeningitis virus?  Academic Article
• Islet inflammation and hyperplasia induced by the pancreatic islet-specific overexpression of interleukin-6 in transgenic mice  Academic Article
• Islet-specific expression of cxcl10 causes spontaneous islet infiltration and accelerates diabetes development  Academic Article
• Isoabzymes: structurally and mechanistically similar catalytic antibodies from the same immunization  Academic Article
• Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in synaptosomes of HIV/gp120 transgenic mice: implications for HIV-associated neurodegeneration  Academic Article
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• Isolated canine mastocytoma cells: propagation and characterization of two cell lines  Academic Article
• Isolated sequences from the linked Myf-5 and MRF4 genes drive distinct patterns of muscle-specific expression in transgenic mice  Academic Article
• Isolation and angiogenesis by endothelial progenitors in the fetal liver  Academic Article
• Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay  Academic Article
• Isolation and culture of primary mouse brain endothelial cells  Academic Article
• Isolation and culture of primary pericytes from mouse brain  Academic Article
• Isolation and proteolytic cleavage of the intact subunit of concanavalin a  Academic Article
• Isolation of 2 novel envelope recombinant leukemogenic viruses from moloney leukemia-virus stocks  Academic Article
• Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor  Academic Article
• Isolation of a functional human gene for brain creatine kinase  Academic Article
• Isolation of antagonists of antigen-specific autoimmune T cell proliferation  Academic Article
• Isolation of highly malignant Thy-1-positive revertants from cultured cloned Thy-1-negative lymphoma-cells of low tumorigenicity  Academic Article
• Isolation of lectins of different specificities on a single affinity adsorbent  Academic Article
• Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak  Academic Article
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• Issls prize winner: Inhibition of nf-kappa b activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging  Academic Article
• Issues in immunologically-mediated hepatic-injury  Academic Article
• JNK1 controls mast cell degranulation and IL-1 beta production in inflammatory arthritis  Academic Article
• JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity  Academic Article
• Jak3 maps to chromosome 8  Academic Article
• Jak3 selectively regulates bax and bcl-2 expression to promote t-cell development  Academic Article
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• Jinx, an mcmv susceptibility phenotype caused by disruption of unc13d: A mouse model of type 3 familial hemophagocytic lymphohistiocytosis  Academic Article
• Joint recognition by cytotoxic t cells of inactivated sendai virus and products of major histocompatibility complex  Academic Article
• Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress  Academic Article
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• Kidney preservation by bone marrow cell transplantation in hereditary nephropathy  Academic Article
• Killing of virus-infected cells by cyto-toxic lymphocytes  Academic Article
• Kinetic and immunochemical studies of a receptor-like protein that binds aromatic hydrocarbons  Academic Article
• Kinetic-analysis of the ca-2+-dependent, membrane-bound, macrophage phospholipase-a2 and the effects of arachidonic-acid  Academic Article
• Kinetics of cellular commitment during stimulation of lymphocytes by lectins  Academic Article
• Kinetics of protective antibodies are determined by the viral surface antigen  Academic Article
• Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia Ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses  Academic Article
• Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice  Academic Article
• Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming  Academic Article
• Knock-down of the 37-kda/67-kda laminin receptor in mouse brain by transgenic expression of specific antisense lrp rna  Academic Article
• Knock-in mice reveal nonsense-mediated mRNA decay in the brain  Academic Article
• Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool  Academic Article
• Knock-in of α3 connexin prevents severe cataracts caused by an α8 point mutation  Academic Article
• Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy  Academic Article
• Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes  Academic Article
• Ksa antigen ep-cam mediates cell-cell adhesion of pancreatic epithelial cells: Morphoregulatory roles in pancreatic islet development  Academic Article
• Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination  Academic Article
• Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis  Academic Article
• Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature  Academic Article
• L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity  Academic Article
• LACTB is a tumour suppressor that modulates lipid metabolism and cell state  Academic Article
• LC3-dependent intracellular membrane tubules induced by gamma-protocadherins A3 and B2: a role for intraluminal interactions  Academic Article
• LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome  Academic Article
• LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element  Academic Article
• LP-BM5 murine retrovirus-induced immunodeficiency disease in allogeneic SCID chimeric mice. Inability to recognize a putative viral superantigen does not prevent induction of disease  Academic Article
• LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage  Academic Article
• LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation  Academic Article
• LPA1 receptor activation promotes renal interstitial fibrosis  Academic Article
• LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation  Academic Article
• LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA)  Academic Article
• LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation  Academic Article
• LRP5 is required for vascular development in deeper layers of the retina  Academic Article
• LXR-mediated inhibition of CD4(+) T helper cells  Academic Article
• LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth  Academic Article
• La autoantigen specifically recognizes a predicted stem-loop in hepatitis B virus RNA  Academic Article
• Labeling and comparative biodistribution of the monoclonal antibody ks1/4 in nude mice bearing human lung adenocarcinoma  Academic Article
• Lack of N-regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences  Academic Article
• Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis  Academic Article
• Lack of class-I H-2-antigens in cells transformed by radiation leukemia-virus is associated with methylation and rearrangement of H-2 DNA  Academic Article
• Lack of correlation between loss of anchorage-independent growth and levels of transformation-specific p53 protein in retinoic acid-treated F9 embryonal carcinoma cells  Academic Article
• Lack of evidence for central T-cell tolerance defects in lupus mice and for V-beta-deleting endogenous superantigens in rats and humans  Academic Article
• Lack of intrinsic ctla-4 expression has minimal effect on regulation of antiviral t-cell immunity  Academic Article
• Lack of mu-opioid receptor leads to an increase in the nmda receptor subunit mrna expression and nmda-induced convulsion  Academic Article
• Lack of prion infectivity in fixed heart tissue from patients with Creutzfeldt-Jakob disease or amyloid heart disease  Academic Article
• Lack of pseudotype formation between human immunodeficiency virus type 1 and Epstein-Barr virus in productively coinfected B lymphoblastoid cell lines  Academic Article
• Lack of relationship between serum gp70 levels and the severity of systemic lupus-erythematosus in mrl/1 mice  Academic Article
• Lack of reward and locomotor stimulation induced by heroin in mu-opioid receptor-deficient mice  Academic Article
• Lack of self-administration of cocaine in dopamine d-1 receptor knock-out mice  Academic Article
• Lack of sterol regulatory element binding factor-1c imposes glial Fatty Acid utilization leading to peripheral neuropathy  Academic Article
• Lack of stimulant and anxiolytic-like effects of ethanol and accelerated development of ethanol dependence in mu-opioid receptor knockout mice  Academic Article
• Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7e3 glycoprotein iib/iiia platelet antibody  Academic Article
• Lacrimal gland inflammation deregulates extracellular matrix remodeling and alters molecular signature of epithelial stem/progenitor cells  Academic Article
• Lactational and postnatal exposure to polychlorinated biphenyls induces sex-specific anxiolytic behavior and cognitive deficit in mice offspring  Academic Article
• Lactic dehydrogenase virus-induced immune complex type of glomerulonephritis  Academic Article
• Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration  Academic Article
• Lambda interferon inhibits hepatitis B and C virus replication  Academic Article
• Laminin stimulates spreading of platelets through integrin alpha(6)beta(1)-dependent activation of GPVI  Academic Article
• Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction  Academic Article
• Large-scale analysis of the human and mouse transcriptomes  Academic Article
• Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures  Academic Article
• Large-scale profiling of Rab GTPase trafficking networks: the membrome  Academic Article
• Late administration of monoclonal-antibody to leukocyte function-antigen 1 abrogates incipient murine cerebral malaria  Academic Article
• Late treatment with polyene antibiotics can prolong the survival time of scrapie-infected animals  Academic Article
• Late-onset corticohippocampal neurodepletion attributable to catastrophic failure of oxidative phosphorylation in MILON mice  Academic Article
• Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (sigma r1)  Academic Article
• Lateral diffusion of surface molecules in animal-cells and tissues  Academic Article
• Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins  Academic Article
• Lcmv-specific, class-ii restricted cytotoxic t-cells in beta-2-microglobulin deficient mice  Academic Article
• Lead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials  Academic Article
• Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors  Academic Article
• Lead optimization of antimalarial propafenone analogues  Academic Article
• Leakage-free bonding of porous membranes into layered microfluidic array systems  Academic Article
• Learned recognition of maternal signature odors mediates the first suckling episode in mice  Academic Article
• Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor  Academic Article
• Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response  Academic Article
• Leiomodins: larger members of the tropomodulin (Tmod) gene family  Academic Article
• Lentiviral gene delivery of vmip-ii to transplanted endothelial cells and endothelial progenitors is proangiogenic in vivo  Academic Article
• Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin alpha v beta 5: implications for angiogenesis in human obesity  Academic Article
• Leptin promotes vascular remodeling and neointimal growth in mice  Academic Article
• Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity  Academic Article
• Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism  Academic Article
• Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza  Academic Article
• Lethal alpha-thalassemia created by gene targeting in mice and its genetic rescue  Academic Article
• Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet  Academic Article
• Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV)  Academic Article
• Leu5enkephalin-encoding sequences are targets for a specific DNA-binding factor.  Academic Article
• Leu628 of the kix domain of cbp is a key residue for the interaction with the mll transactivation domain  Academic Article
• Leukocyte cd11b expression is not essential for the development of atherosclerosis in mice  Academic Article
• Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM)  Academic Article
• Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size  Academic Article
• Leukocyte-derived hepatic lipase increases hdl and decreases en face aortic atherosclerosis in ldlr-/- mice expressing cetp  Academic Article
• Leukotriene C synthase in mouse mastocytoma cells. An enzyme distinct from cytosolic and microsomal glutathione transferases  Academic Article
• Leukotriene C4 synthase: characterization in mouse mastocytoma cells  Academic Article
• Lhx1 maintains synchrony among circadian oscillator neurons of the SCN  Academic Article
• Library construction for next-generation sequencing: overviews and challenges  Academic Article
• Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor  Academic Article
• Ligand-induced internalization of the epidermal growth-factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors  Academic Article
• Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo  Academic Article
• Like-acetylglucosaminyltransferase (large)-dependent modification of dystroglycan at thr-317/319 is required for laminin binding and arenavirus infection  Academic Article
• Limited diversity of t-cell receptor gamma-chain expression of murine thy-1+ dendritic epidermal-cells revealed by v-gamma-3-specific monoclonal-antibody  Academic Article
• Limited functional diversity in kappa-light-chains - junctional sequences from CD43(+)B220(+) early B-cell progenitors resemble those from peripheral B-cells  Academic Article
• Limited proliferative potential of primitive hematopoietic stem cells: hematopoiesis by clonal succession  Academic Article
• Limiting the available t-cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology  Academic Article
• Limits of a deletion spanning Tlr4 in C57BL/10ScCr mice  Academic Article
• Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro  Academic Article
• Linear padre t helper epitope and carbohydrate b cell epitope conjugates induce specific high titer igg antibody responses  Academic Article
• Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes  Academic Article
• Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression  Academic Article
• Lipid binding promotes oligomerization and focal adhesion activity of vinculin  Academic Article
• Lipid tucaresol as an adjuvant for methamphetamine vaccine development  Academic Article
• Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors  Academic Article
• Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappa B independently of platelet-activating factor  Academic Article
• Lipopolysaccharide induces hyporesponsiveness to its own action in raw 2647 cells  Academic Article
• Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2  Academic Article
• Lipopolysaccharide sensing an important factor in the innate immune response to gram-negative bacterial infections: Benefits and hazards of lps hypersensitivity  Academic Article
• Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway  Academic Article
• Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock  Academic Article
• Lipopolysaccharide-induced il-12 expression in the central nervous system and cultured astrocytes and microglia  Academic Article
• Lipopolysaccharide-treated RAW 264.7 cells produce a mediator that inhibits lipoprotein lipase in 3T3-L1 cells  Academic Article
• Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium  Academic Article
• Lipoproteins inhibit macrophage activation by lipoteichoic acid  Academic Article
• Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct  Academic Article
• Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene  Academic Article
• Liposomal packaging generates Wnt protein with in vivo biological activity  Academic Article
• Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs  Academic Article
• Liquid chromatography-fourier transform ion cyclotron resonance mass spectrometric characterization of protein kinase c phosphorylation  Academic Article
• Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile x syndrome  Academic Article
• Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells  Academic Article
• Live cell calcium imaging of dissociated vomeronasal neurons  Academic Article
• Liver (b-type) phosphofructokinase messenger-rna - cloning, structure, and expression  Academic Article
• Liver autoimmunity triggered by microbial activation of natural killer T cells  Academic Article
• Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man  Academic Article
• Liver is liver and blood is blood, and finally the twain have met  Academic Article
• Liver x receptor and retinoic x receptor mediated abca1 regulation and cholesterol efflux in macrophage cells - messenger rna measured by branched DNA technology  Academic Article
• Liver x receptor-retinoid x receptor (lxr-rxr) heterodimer cistrome reveals coordination of lxr and ap1 signaling in keratinocytes  Academic Article
• Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing  Academic Article
• Lkb1 and sad kinases define a pathway required for the polarization of cortical neurons  Academic Article
• Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling  Academic Article
• Local not systemic modulation of dendritic cell s1p receptors in lung blunts virus-specific immune responses to influenza  Academic Article
• Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina  Academic Article
• Localization and substrate selectivity of sea urchin multidrug (MDR) efflux transporters  Academic Article
• Localization at high-resolution of antibody-induced mobilization of vaccinia virus hemagglutinin and the major histocompatibility antigens on the plasma-membrane of infected-cells  Academic Article
• Localization of 2 epitopes of apolipoprotein-a-i that are exposed on human high-density lipoproteins using monoclonal-antibodies and synthetic peptides  Academic Article
• Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as neural signaling molecules  Academic Article
• Localization of a passively transferred human recombinant monoclonal antibody to herpes simplex virus glycoprotein D to infected nerve fibers and sensory neurons in vivo  Academic Article
• Localization of a stable neural correlate of associative memory  Academic Article
• Localization of an apolipoprotein-a-i epitope critical for activation of lecithin-cholesterol acyltransferase  Academic Article
• Localization of an apolipoprotein-a-i epitope critical for lipoprotein-mediated cholesterol efflux from monocytic cells  Academic Article
• Localization of cholesterol, amyloid and glia in alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (tof-sims) and immunofluorescence imaging  Academic Article
• Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression  Academic Article
• Localization of sarcomeric proteins during myofibril assembly in cultured mouse primary skeletal myotubes  Academic Article
• Localization of the beta(beta)(3)-adrenoceptor in the human gastrointestinal tract: An immunohistochemical study  Academic Article
• Localization of the binding-site for the human high-affinity fc receptor on igg  Academic Article
• Localization of the human jun protooncogene to chromosome region 1p31-32  Academic Article
• Localization of the monocyte-binding region on human immunoglobulin-g  Academic Article
• Localization of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected mouse eyes  Academic Article
• Locally synchronized synaptic inputs  Academic Article
• Loci predisposing to autoimmunity in MRL-Fas(lpr) and C57BL/6-Fas(lpr) mice  Academic Article
• Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels  Academic Article
• Loganin improves learning and memory impairments induced by scopolamine in mice  Academic Article
• Long latency event-related potentials in mice: Effects of stimulus characteristics and strain  Academic Article
• Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling  Academic Article
• Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy  Academic Article
• Long-term growth suppression of human glioma xenografts by chemoimmunoconjugates of 4-desacetylvinblastine-3-carboxyhydrazide and monoclonal-antibody 9.2.27  Academic Article
• Long-term monitoring of circadian rhythms in c-fos gene expression from suprachiasmatic nucleus cultures  Academic Article
• Long-term persistence and reactivation of t cell memory in the lung of mice infected with respiratory syncytial virus  Academic Article
• Long-term phorbol ester treatment down-regulates the beta(3)-adrenergic receptor in 3t3-f442a adipocytes  Academic Article
• Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions  Academic Article
• Long-term xenogeneic chimeras - full differentiation of rat t-cells and b-cells in scid mice  Academic Article
• Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract  Academic Article
• Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation  Academic Article
• Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids  Academic Article
• Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope  Academic Article
• Loss of bax alters tumor spectrum and tumor numbers in arf-deficient mice  Academic Article
• Loss of histaminergic modulation of thermoregulation and energy homeostasis in obese mice  Academic Article
• Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells  Academic Article
• Loss of lysophosphatidic acid receptor LPA(1) alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex  Academic Article
• Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human β-amyloid precursor protein  Academic Article
• Loss of nicotine-induced behavioral sensitization in mu-opioid receptor knockout mice  Academic Article
• Loss of p53 compensates for alpha(v)-integrin function in retinal neovascularization  Academic Article
• Loss of retinal cadherin facilitates mammary tumor progression and metastasis  Academic Article
• Loss of sex discrimination and male-male aggression in mice deficient for trp2  Academic Article
• Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome  Academic Article
• Loss of spinal substance P pain transmission under the condition of LPA1 receptor-mediated neuropathic pain  Academic Article