subject area of

• "Viral deja vu" elicits organ-specific immune disease independent of reactivity to self  Academic Article
• 'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast  Academic Article
• (18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils  Academic Article
• -Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity  Academic Article
• 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation  Academic Article
• 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia  Academic Article
• 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females  Academic Article
• 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination  Academic Article
• 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles  Academic Article
• 2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors  Academic Article
• 2-Aminobenzimidazoles as potent Aurora kinase inhibitors  Academic Article
• 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases  Academic Article
• 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of beta-amyloid aggregation  Academic Article
• 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution  Academic Article
• 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1  Academic Article
• 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 2  Academic Article
• 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth  Academic Article
• 4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase  Academic Article
• 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency  Academic Article
• 5,​6-methanoleukotriene A(4): a potent specific inhibitor for 5-​lipoxygenase  Academic Article
• 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia  Academic Article
• 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission  Academic Article
• 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern  Academic Article
• 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent  Academic Article
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)  Academic Article
• 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2  Academic Article
• 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience  Academic Article
• 8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents  Academic Article
• 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors  Academic Article
• A 1,064 bp fragment from the promoter region of the Col11a2 gene drives LacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos  Academic Article
• A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
• A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus  Academic Article
• A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia  Academic Article
• A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity  Academic Article
• A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines  Academic Article
• A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells  Academic Article
• A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response  Academic Article
• A CreER mouse to study melanin concentrating hormone signaling in the developing brain  Academic Article
• A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth  Academic Article
• A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence  Academic Article
• A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication  Academic Article
• A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the nkg2d receptor  Academic Article
• A FAAH-regulated class of N-acyl taurines that activates TRP ion channels  Academic Article
• A Gja8 (Cx50) point mutation causes an alteration of α3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice  Academic Article
• A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection  Academic Article
• A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids  Academic Article
• A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells  Academic Article
• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis  Academic Article
• A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate  Academic Article
• A Protective Strategy against Hyperinflammatory Responses Requiring the Nontranscriptional Actions of GPS2  Academic Article
• A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum  Academic Article
• A T cell receptor-specific blockade of positive selection  Academic Article
• A THEMIS:SHP1 complex promotes T-cell survival  Academic Article
• A TRP channel that senses cold stimuli and menthol  Academic Article
• A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction  Academic Article
• A binding site for homeodomain and pax proteins is necessary for l1 cell adhesion molecule gene expression by pax-6 and bone morphogenetic proteins  Academic Article
• A binding site for pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord  Academic Article
• A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy  Academic Article
• A brain detoxifying enzyme for organophosphorus nerve poisons  Academic Article
• A candidate circuit approach to investigating autism  Academic Article
• A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation  Academic Article
• A catechol-O-methyltransferase that is essential for auditory function in mice and humans  Academic Article
• A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1)  Academic Article
• A cell-autonomous requirement for the cell cycle regulatory protein, rb, in neuronal migration  Academic Article
• A cellular gene encodes scrapie prp 27-30 protein  Academic Article
• A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis  Academic Article
• A ceramide-1-phosphate analogue, pcera-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages  Academic Article
• A change in the conformation of prions accompanies the emergence of a new prion strain  Academic Article
• A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins  Academic Article
• A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor  Academic Article
• A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor  Academic Article
• A chemically induced vaccine strategy for prostate cancer  Academic Article
• A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase  Academic Article
• A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses  Academic Article
• A chimeric mouse model of Gaucher disease  Academic Article
• A combinatorial system for cloning and expressing the catalytic antibody repertoire in escherichia-coli  Academic Article
• A common and unstable copy number variant is associated with differences in glo1 expression and anxiety-like behavior  Academic Article
• A common antiviral cytotoxic lymphocyte-t epitope for diverse major histocompatibility complex haplotypes - implications for vaccination  Academic Article
• A common solution to group 2 influenza virus neutralization  Academic Article
• A comparative analysis of the immunological evolution of antibody 28B4  Academic Article
• A comparative encyclopedia of DNA elements in the mouse genome  Academic Article
• A comparison of 129S2/SvHsd and C57BL/6JO1aHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically modified mice  Academic Article
• A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis  Academic Article
• A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models  Academic Article
• A comparison of t cell memory against the same antigen induced by virus versus intracellular bacteria  Academic Article
• A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis  Academic Article
• A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol  Academic Article
• A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells  Academic Article
• A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform  Academic Article
• A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses  Academic Article
• A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles  Academic Article
• A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase  Academic Article
• A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions  Academic Article
• A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function  Academic Article
• A cost-effective fluorescence mini-microscope for biomedical applications  Academic Article
• A critical evaluation of a nicotine vaccine within a self-administration behavioral model  Academic Article
• A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection  Academic Article
• A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
• A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling  Academic Article
• A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy  Academic Article
• A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response  Academic Article
• A curly-tail modifier locus, mct1, on mouse chromosome-17  Academic Article
• A customized self-assembling peptide hydrogel for dental pulp tissue engineering  Academic Article
• A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally  Academic Article
• A designer AAV variant permits efficient retrograde access to projection neurons  Academic Article
• A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle  Academic Article
• A direct GABAergic output from the basal ganglia to frontal cortex  Academic Article
• A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification  Academic Article
• A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d  Academic Article
• A distribution-free test for tumor-growth curve analyses with application to an animal tumor-immunotherapy experiment  Academic Article
• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use  Academic Article
• A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes  Academic Article
• A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis  Academic Article
• A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli  Academic Article
• A dual-function DNA vaccine encoding carcinoembryonic antigen and cd40 ligand trimer induces t cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice  Academic Article
• A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis  Academic Article
• A dynamic search process underlies microRNA targeting  Academic Article
• A dystroglycan mutation associated with limb-girdle muscular dystrophy  Academic Article
• A factor IX-deficient mouse model for hemophilia B gene therapy  Academic Article
• A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol)  Academic Article
• A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange  Academic Article
• A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition  Academic Article
• A fluorescent plate reader assay for ceramide kinase  Academic Article
• A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome  Academic Article
• A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity  Academic Article
• A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function  Academic Article
• A fragment of human TrpRS as a potent antagonist of ocular angiogenesis  Academic Article
• A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells  Academic Article
• A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen  Academic Article
• A functional genomics strategy reveals Rora as a component of the mammalian circadian clock  Academic Article
• A functional hot spot for antigen recognition in a superagonist TCR/MHC complex  Academic Article
• A functional interaction between RIP140 and PGC-1 alpha regulates the expression of the lipid droplet protein CIDEA  Academic Article
• A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding  Academic Article
• A gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesity  Academic Article
• A gene atlas of the mouse and human protein-encoding transcriptomes  Academic Article
• A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells  Academic Article
• A genetic analysis of lupus  Academic Article
• A genetic approach to the generation of antibodies with enhanced catalytic activities  Academic Article
• A genetic determinant of the striatal dopamine response to alcohol in men  Academic Article
• A genetic determinant that specifically regulates the frequency of hematopoietic stem cells  Academic Article
• A genetic marker in the variable region of light chains of mouse immunoglobulins  Academic Article
• A genetic-locus regulates the expression of tissue-specific messenger-rnas from multiple transcription units  Academic Article
• A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing  Academic Article
• A genetically humanized mouse model for hepatitis C virus infection  Academic Article
• A genomic screen for activators of the antioxidant response element  Academic Article
• A genomic screen identifies TYRO3 as a MITF regulator in melanoma  Academic Article
• A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse  Academic Article
• A global map of lipid-binding proteins and their ligandability in cells  Academic Article
• A glycoengineered enzyme with multiple mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes  Academic Article
• A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival  Academic Article
• A heat-modifiable outer-membrane protein carries an antigen specific for the species Yersinia-enterocolitica and Yersinia-pseudotuberculosis  Academic Article
• A heat-sensitive TRP channel expressed in keratinocytes  Academic Article
• A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain  Academic Article
• A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis  Academic Article
• A highly conserved neutralizing epitope on group 2 influenza a viruses  Academic Article
• A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia  Academic Article
• A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature  Academic Article
• A hormone-dependent module regulating energy balance  Academic Article
• A human aminoacyl-tRNA synthetase as a regulator of angiogenesis  Academic Article
• A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo  Academic Article
• A human recombinant monoclonal antibody to cocaine: preparation, characterization and behavioral studies  Academic Article
• A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol  Academic Article
• A human-brain glycoprotein related to the mouse-cell adhesion molecule l1  Academic Article
• A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy  Academic Article
• A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus  Academic Article
• A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen  Academic Article
• A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters  Academic Article
• A keratinocyte-responsive gamma delta tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis  Academic Article
• A key role for lipoic acid synthesis during Plasmodium liver stage development  Academic Article
• A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues  Academic Article
• A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna  Academic Article
• A large noncoding rna is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas  Academic Article
• A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells  Academic Article
• A legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis  Academic Article
• A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status  Academic Article
• A leukocyte homologue of the il-8 receptor cxcr-2 mediates the accumulation of macrophages in atherosclerotic lesions of ldl receptor-deficient mice  Academic Article
• A liver-selective LXR inverse agonist that suppresses hepatic steatosis  Academic Article
• A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses  Academic Article
• A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGf/TNF receptor family  Academic Article
• A major conformational change in p97 aaa atpase upon atp binding  Academic Article
• A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells  Academic Article
• A metabolomics strategy for detecting protein-metabolite interactions to identify natural nuclear receptor ligands  Academic Article
• A method for rapid mouse siderocyte enrichment  Academic Article
• A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting  Academic Article
• A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids  Academic Article
• A minimally lipidated form of cell-derived apolipoprotein e exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins  Academic Article
• A minor catalytic activity of src family kinases is sufficient for maximal activation of mast cells via the high-affinity ige receptor  Academic Article
• A mitochondrial targeting two-channel responsive fluorescence probe for imaging the superoxide radical anion in vitro and in vivo  Academic Article
• A model for familial exudative vitreoretinopathy caused by LPR5 mutations  Academic Article
• A model of measles virus-induced immunosuppression: Enhanced susceptibility of neonatal human pbls  Academic Article
• A model of the cell-autonomous mammalian circadian clock  Academic Article
• A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells  Academic Article
• A molecular link between the active component of marijuana and Alzheimer's disease pathology  Academic Article
• A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3  Academic Article
• A molecular switch controls interspecies prion disease transmission in mice  Academic Article
• A monoclonal-antibody directed against the beta-1-adrenergic receptor from turkey erythrocyte-membranes  Academic Article
• A monoclonal-antibody specific for conidia and mycelium wall layer of penicillium and aspergillus  Academic Article
• A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration  Academic Article
• A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons  Academic Article
• A mouse model for nonsyndromic deafness (dfnb12) links hearing loss to defects in tip links of mechanosensory hair cells  Academic Article
• A mouse model of accelerated liver aging caused by a defect in DNA repair  Academic Article
• A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice  Academic Article
• A multifunctional bispecific antibody protects against Pseudomonas aeruginosa  Academic Article
• A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen  Academic Article
• A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans  Academic Article
• A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response  Academic Article
• A murine t-cell receptor gene-complex - isolation, structure and rearrangement  Academic Article
• A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen  Academic Article
• A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα  Academic Article
• A near-IR uncaging strategy based on cyanine photochemistry  Academic Article
• A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain  Academic Article
• A new approach to high-sensitivity differential hybridization  Academic Article
• A new method of embryonic culture for assessing global changes in brain organization  Academic Article
• A new murine CD4+ T cell subset with an unrestricted cytokine profile  Academic Article
• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis  Academic Article
• A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity  Academic Article
• A nonapoptotic role for BAX and BAK in eicosanoid metabolism  Academic Article
• A novel 2 '-(n-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models  Academic Article
• A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma  Academic Article
• A novel ELISA for mouse activated protein C in plasma  Academic Article
• A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target  Academic Article
• A novel Netrin-l-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching  Academic Article
• A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease  Academic Article
• A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells  Academic Article
• A novel and simple method for culturing pericytes from mouse brain  Academic Article
• A novel approach for in vivo measurement of mouse red cell redox status  Academic Article
• A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system  Academic Article
• A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis  Academic Article
• A novel class II MHC molecule with unusual tissue distribution  Academic Article
• A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties  Academic Article
• A novel cross-talk in diacylglycerol signaling the rac-gap beta 2-chimaerin is negatively regulated by protein kinase c delta-mediated phosphorylation  Academic Article
• A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1  Academic Article
• A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects  Academic Article
• A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis  Academic Article
• A novel generation of heparan sulfate mimetics for the treatment of prion diseases  Academic Article
• A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation  Academic Article
• A novel method for generating region-specific monoclonal-antibodies to modified proteins - application to the identification of human glucosylated low-density lipoproteins  Academic Article
• A novel method to establish microglia-free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia  Academic Article
• A novel monoclonal antibody, L1A3, is directed to the functional site of the αv integrin subunit  Academic Article
• A novel neuron-specific DNA end-binding factor in the murine brain  Academic Article
• A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action  Academic Article
• A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease  Academic Article
• A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β  Academic Article
• A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal cns  Academic Article
• A novel synthetic bipartite carrier protein for developing glycotope-based vaccines  Academic Article
• A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system  Academic Article
• A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines  Academic Article
• A novel vascular endothelial growth factor heparin-binding domain substructure binds to glycosaminoglycans in vivo and localizes to tumor microvascular endothelium  Academic Article
• A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests  Academic Article
• A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct  Academic Article
• A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects  Academic Article
• A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity  Academic Article
• A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration  Academic Article
• A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas  Academic Article
• A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects  Academic Article
• A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice  Academic Article
• A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones  Academic Article
• A peripheral and central t-cell antigen recognized by a monoclonal thymocytotoxic autoantibody from new-zealand black mice  Academic Article
• A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries  Academic Article
• A phase i/ib trial of murine monoclonal anti-gd2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma - a report of the children's cancer group  Academic Article
• A phase-i study of human mouse chimeric antiganglioside gd2 antibody ch14.18 in patients with neuroblastoma  Academic Article
• A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins  Academic Article
• A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia  Academic Article
• A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein  Academic Article
• A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase ii in t cells: From activation to unresponsiveness  Academic Article
• A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer's disease mice  Academic Article
• A platform stratifying a sequestering agent and a pharmacological antagonist as a means to negate botulinum neurotoxicity  Academic Article
• A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice  Academic Article
• A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding  Academic Article
• A population of murine gamma delta T cells that recognize an inducible MHC class Ib molecule  Academic Article
• A porous silicon-based optical interferometric biosensor  Academic Article
• A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic  Academic Article
• A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis  Academic Article
• A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo  Academic Article
• A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake  Academic Article
• A potential suppressive effect of natural antisense IL-1β RNA on lipopolysaccharide-induced IL-1β expression  Academic Article
• A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis  Academic Article
• A proapoptotic peptide for the treatment of solid tumors  Academic Article
• A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale  Academic Article
• A putative bacterial ABC transporter circumvents the essentiality of signal peptidase  Academic Article
• A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes  Academic Article
• A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions  Academic Article
• A rabbit antiserum detects a vh j558 subgroup marker highly expressed among anti-alprenolol antibodies  Academic Article
• A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation  Academic Article
• A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists  Academic Article
• A rationally designed agonist antibody fragment that functionally mimics thrombopoietin  Academic Article
• A receptor-induced by lymphocyte-activation (ILA) - a new member of the human nerve-growth-factor tumor-necrosis-factor receptor family  Academic Article
• A recombinant antibody interleukin-2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice  Academic Article
• A recombinant human enzyme for enhanced interstitial transport of therapeutics  Academic Article
• A recombinant minigene vaccine containing a nonameric cytotoxic-t-lymphocyte epitope confers limited protection against listeria monocytogenes infection  Academic Article
• A recurrent idiotype on monoclonal anti-human ia antibodies  Academic Article
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• An engineered mutant of hiv-1 gp120 formulated with adjuvant quil a promotes elicitation of antibody responses overlapping the cd4-binding site  Academic Article
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• An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses  Academic Article
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• Analysis of endogenous and exogenous antigens in the nervous-system using whole animal sections  Academic Article
• Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies  Academic Article
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• Analysis of lymphocytic choriomeningitis virus gene expression in acutely and persistently infected mice  Academic Article
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• Analysis of persistent virus-infections by insitu hybridization to whole-mouse sections  Academic Article
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• Analysis of protein-S C4b-binding protein interactions by homology modeling and inhibitory antibodies  Academic Article
• Analysis of rrna processing and translation in mammalian cells using a synthetic 18s rrna expression system  Academic Article
• Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools  Academic Article
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• Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex  Academic Article
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• Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera  Academic Article
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• Aneuploidy Causes Non-genetic Individuality  Academic Article
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• Animal models for retrovirus-induced immunodeficiency disease  Academic Article
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• Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?  Academic Article
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• Annotating STEAP1 regulation in prostate cancer with (89)Zr immuno-PET  Academic Article
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• Antifungal imidazoles block assembly of inducible no synthase into an active dimer  Academic Article
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• Antigen-driven B cell differentiation in vivo  Academic Article
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• Brain region mapping using global metabolomics  Academic Article
• Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina  Academic Article
• Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice  Academic Article
• Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor  Academic Article
• Brain-specific knock-out of hypoxia-inducible factor-1α reduces rather than increases hypoxic-ischemic damage  Academic Article
• Branched fatty acid esters of hdroxy fatty acids (FAHFAs) protect against colitis by regulating gut innate and adaptive immune responses  Academic Article
• Breadth of tuning and taste coding in mammalian taste buds  Academic Article
• Break for SCIDs  Academic Article
• Break of T cell ignorance to a viral antigen in the liver induces hepatitis  Academic Article
• Breaking the one antibody-one target axiom  Academic Article
• Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice  Academic Article
• Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection  Academic Article
• Breast cancer cell lines grown in vivo: What goes in isn't always the same as what comes out  Academic Article
• Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts  Academic Article
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• Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist  Academic Article
• Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin  Academic Article
• Broadly neutralizing antibodies abrogate established hepatitis C virus infection  Academic Article
• Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge  Academic Article
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• Brown adipogenic reprogramming induced by a small molecule  Academic Article
• Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1  Academic Article
• Building better vasculature  Academic Article
• Building zinc fingers by selection - toward a therapeutic application  Academic Article
• Bulk segregation mapping of mutations in closely related strains of mice  Academic Article
• Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system  Academic Article
• Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax  Academic Article
• C-fos deficiency inhibits induction of mrna for some, but not all, neurotransmitter biosynthetic enzymes by immobilization stress  Academic Article
• C-fos is not essential for v-abl-induced lymphomagenesis  Academic Article
• C-fos is required for malignant progression of skin tumors  Academic Article
• C-jun causes focus formation and anchorage-independent growth in culture but is nontumorigenic  Academic Article
• C-myc augments gamma irradiation-induced apoptosis by suppressing bcl-x-l  Academic Article
• C-myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways  Academic Article
• C-myc is essential for vasculogenesis and angiogenesis during development and tumor progression  Academic Article
• C-myc-mediated regulation of telomerase activity is disabled in immortalized cells  Academic Article
• C-src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 (bmk1)  Academic Article
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• C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment  Academic Article
• C5L2, a nonsignaling C5A binding protein  Academic Article
• CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells  Academic Article
• CCR5 knockout prevents neuronal injury and behavioral impairment induced in a transgenic mouse model by a CXCR4-using HIV-1 glycoprotein 120  Academic Article
• CD14 is a pattern recognition receptor  Academic Article
• CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth  Academic Article
• CD200 expression on tumor cells suppresses antitumor immunity: new approaches to cancer immunotherapy  Academic Article
• CD4 is expressed on murine pluripotent hematopoietic stem cells  Academic Article
• CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer  Academic Article
• CD4(+) T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8(+) T-cell immune responses  Academic Article
• CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS)  Academic Article
• CD4+ T cells from IRF-1-deficient mice exhibit altered patterns of cytokine expression and cell subset homeostasis  Academic Article
• CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction  Academic Article
• CD4+ T-cell help in the tumor milieu is required for recruitment and cytolytic function of CD8+ T lymphocytes  Academic Article
• CD4+8- and CD4-8+ mature thymocytes require different post-selection processing for final development  Academic Article
• CD4+CD8- thymocytes from neonatal mice induce IgM production in SCID mice  Academic Article
• CD4-CD8- thymocytes that express the T-cell receptor may have previously expressed CD8  Academic Article
• CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5  Academic Article
• CD40 activation rescues antiviral CD8+ T cells from PD-1-mediated exhaustion  Academic Article
• CD8 T cell defect of TNF-α and IL-2 in DNAM-1 deficient mice delays clearance in vivo of a persistent virus infection.  Academic Article
• CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes  Academic Article
• CD8(+) T cell-mediated spontaneous diabetes in neonatal mice  Academic Article
• CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection  Academic Article
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• CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles  Academic Article
• CD8+ memory T cells appear exhausted within hours of acute virus infection  Academic Article
• CD8αα and ‐αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I  Academic Article
• CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis  Academic Article
• CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma  Academic Article
• CFTR Folding Consortium: methods available for studies of CFTR folding and correction  Academic Article
• CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells  Academic Article
• CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts  Academic Article
• CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation  Academic Article
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• CREB: The unindicted cancer co-conspirator  Academic Article
• CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement  Academic Article
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• CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma  Academic Article
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• CTL access to tissue antigen is restricted in vivo  Academic Article
• CTL escape viral variants. II. Biologic activity in vivo  Academic Article
• CTLA-4 blockade enhances the CTL responses to the p53 self-tumor antigen  Academic Article
• CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria  Academic Article
• CTLA4 expression is an indicator and regulator of steady-state CD4(+)FoxP3(+) T cell homeostasis  Academic Article
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• CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation  Academic Article
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• CXCR4 expression in prostate cancer progenitor cells  Academic Article
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• Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo  Academic Article
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• Cadherin 23 is a component of the tip link in hair-cell stereocilia  Academic Article
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• Calcineurin negatively regulates tlr-mediated activation pathways  Academic Article
• Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation  Academic Article
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• Calcium dynamics are altered in cortical neurons lacking the calmodulin-binding protein RC3  Academic Article
• Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity  Academic Article
• Calpain-mediated down-regulation of myelin-associated glycoprotein in lysophosphatidic acid-induced neuropathic pain  Academic Article
• Camkii regulates the frequency-response function of hippocampal synapses for the production of both ltd and ltp  Academic Article
• Can gene delivery close the door to HIV-1 entry after escape?  Academic Article
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• Cancer gene therapy using a novel secretable trimeric trail  Academic Article
• Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts  Academic Article
• Cancer: Aneuploidy drives a mutator phenotype in cancer  Academic Article
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• Cannabinoid CB1 receptors regulate neuronal TNF-alpha effects in experimental autoimmune encephalomyelitis  Academic Article
• Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis  Academic Article
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• Carboxylesterase isoenzyme specific deacylation of diacetoxyscirpenol (anguidine)  Academic Article
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• Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo  Academic Article
• Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis  Academic Article
• Cargo selection by the COPII budding machinery during export from the ER  Academic Article
• Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1  Academic Article
• Casein kinase 1 delta-dependent Wee1 protein degradation  Academic Article
• Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis  Academic Article
• Caspase cascades in human immunodeficiency virus-associated neurodegeneration  Academic Article
• Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles  Academic Article
• Cat-ELCCA: A robust method to monitor the fattty acid acyltransferase activityy of Grehlin O-Acyltransferase (GOAT)  Academic Article
• Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: Crystal structures of abzyme 21D8  Academic Article
• Catalytic antibodies - the rerouting of chemical-reactions  Academic Article
• Catalytic antibodies with lipase activity and R-substrate or S-substrate selectivity  Academic Article
• Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice  Academic Article
• Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes  Academic Article
• Catalytic soman scavenging by the Y337A/F338A acetylcholinesterase mutant assisted with novel site-directed aldoximes  Academic Article
• Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2  Academic Article
• Catecholamines in mutant mouse cerebellum - fluorescence microscopic and chemical studies  Academic Article
• Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity  Academic Article
• Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia  Academic Article
• Cbp histone acetyltransferase activity is a critical component of memory consolidation  Academic Article
• Cbp/p300 taz1 domain forms a structured scaffold for ligand binding  Academic Article
• Cc chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: Critical role in migration from the tumor site to draining lymph nodes  Academic Article
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• Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue  Academic Article
• Cd11a/cd18 (lfa-1) integrin engagement enhances biosynthesis of early cytokines by activated t-cells  Academic Article
• Cd14 - cell-surface receptor and differentiation marker  Academic Article
• Cd14 is required for myd88-independent lps signaling  Academic Article
• Cd2-deficient mice generate virus-specific cytotoxic t-lymphocytes upon infection with lymphocytic choriomeningitis virus  Academic Article
• Cd22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of b cells  Academic Article
• Cd22 regulates adaptive and innate immune responses of b cells  Academic Article
• Cd22-antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at c-2 and c-9 of sialic acid scaffold  Academic Article
• Cd28 plays a critical role in the segregation of pkc theta within the immunologic synapse  Academic Article
• Cd36 is a sensor of diacylglycerides  Academic Article
• Cd38 signaling in b lymphocytes is controlled by its ectodomain but occurs independently of enzymatically generated adp-ribose or cyclic adp-ribose  Academic Article
• Cd4 t cell control primary measles virus infection of the cns: Regulation is dependent on combined activity with either cd8 t cells or with b cells: Cd4, cd8 or b cells alone are ineffective  Academic Article
• Cd4(+) t cells induced by a DNA vaccine: Immunological consequences of epitope-specific lysosomal targeting  Academic Article
• Cd4-deficient mice have reduced levels of memory cytotoxic t lymphocytes after immunization and show diminished resistance to subsequent virus challenge  Academic Article
• Cd40 ligand-mediated interactions are involved in the generation of memory cd8(+) cytotoxic t lymphocytes (ctl) but are not required for the maintenance of ctl memory following virus infection  Academic Article
• Cd40l-deficient mice show deficits in antiviral immunity and have an impaired memory cd8(+) ctl response  Academic Article
• Cd44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma  Academic Article
• Cd69 down-modulation and inhibition of thymic egress by short- and long-term selective chemical agonism of sphingosine 1-phosphate receptors  Academic Article
• Cd8 t cells are sufficient to mediate allorecognition and allograft rejection  Academic Article
• Cd81 and cd28 costimulate t cells through distinct pathways  Academic Article
• Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway  Academic Article
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• Cell and agonist-specific regulation of genes for matrix metalloproteinases and their tissue inhibitors by primary glial cells  Academic Article
• Cell co-culture patterning using aqueous two-phase systems  Academic Article
• Cell cooperation during in vivo anti-hapten antibody responses. VI. Evidence for an allogeneic effect replacing one of two helper T cells  Academic Article
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• Cell death, DNA breaks and possible rearrangements: an alternative view  Academic Article
• Cell entry of lymphocytic choriomeningitis virus is restricted in myotubes  Academic Article
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• Cell interactions in the primary immune response in vitro: A requirement for specific cell clusters  Academic Article
• Cell proliferation and cytokine production by CD4+ cells from old mice  Academic Article
• Cell proliferation and expression of cytokeratin filaments in F9 embryonal carcinoma cells  Academic Article
• Cell sorting-out is modulated by both the specificity and amount of different cell-adhesion molecules (cams) expressed on cell-surfaces  Academic Article
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• Cell surface 4-1bbl mediates sequential signaling pathways 'downstream' of tlr and is required for sustained tnf production in macrophages  Academic Article
• Cell surface immunoglobulin regulated checkpoints in chicken B cell development  Academic Article
• Cell surface receptors in lysophospholipid signaling  Academic Article
• Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-jun-n-terminal kinase activation in cultured neurons  Academic Article
• Cell-adhesion alters gene-transcription in chicken-embryo brain-cells and mouse embryonal carcinoma-cells  Academic Article
• Cell-adhesion molecules  Academic Article
• Cell-adhesion molecules as targets for hox genes - neural cell-adhesion molecule promoter activity is modulated by cotransfection with hox-2.5 and hox-2.4  Academic Article
• Cell-adhesion molecules: A molecular basis for animal form  Academic Article
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• Cell-autonomous hepatic circadian clock regulates polyamine synthesis  Academic Article
• Cell-based optimization of novel benzamides as potential antimalarial leads  Academic Article
• Cell-cell interactions in antibody production  Academic Article
• Cell-free expression of disulfide-containing eukaryotic proteins for structural biology  Academic Article
• Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development  Academic Article
• Cell-free synthesis and segregation of beta-2-microglobulin  Academic Article
• Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific cd8(+) t cell deletion and viral persistence in vivo  Academic Article
• Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice  Academic Article
• Cell-specific down-regulation of the beta(3)-adrenergic receptor  Academic Article
• Cell-specific susceptibility to prion strains is a property of the intact cell  Academic Article
• Cell-surface structures involved in t-cell activation  Academic Article
• Cell-type independent myc target genes reveal a primordial signature involved in biomass accumulation  Academic Article
• Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: a consequence of peptide-dependent allorecognition  Academic Article
• Cells that express viral-antigens but lack h-2 determinants are not lysed by immune thymus-derived lymphocytes but are lysed by other antiviral immune attack mechanisms  Academic Article
• Cellular and molecular heterogeneity of h-2kk antigens  Academic Article
• Cellular and molecular mechanisms of memory: The ltp connection  Academic Article
• Cellular applications of a sensitive and selective fiber optic nitric oxide biosensor based on a dye-labeled heme domain of soluble guanylate cyclase  Academic Article
• Cellular deficit in thymectomized mice  Academic Article
• Cellular events associated with immunogenesis of anti-erythrocyte autoantibody responses of nzb mice  Academic Article
• Cellular events associated with regression and progression of murine (Moloney) sarcomas  Academic Article
• Cellular immune and cytokine pathways resulting in tissue factor expression and relevance to septic shock  Academic Article
• Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy  Academic Article
• Cellular localization of type 1 plasminogen activator inhibitor messenger RNA and protein in murine renal tissue  Academic Article
• Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5  Academic Article
• Cellular prion protein conformation and function  Academic Article
• Cellular requirements for antigen presentation in the induction of a thymus-independent antibody response in vitro  Academic Article
• Cellular requirements for the primary in vitro antibody response to DNP-ficoll  Academic Article
• Cellular signaling by an agonist-activated receptor g(s)alpha fusion protein  Academic Article
• Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene  Academic Article
• Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes  Academic Article
• Central nervous system (cns)-resident natural killer cells suppress th17 responses and cns autoimmune pathology  Academic Article
• Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle  Academic Article
• Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones  Academic Article
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• Ceramide mediates the rapid phase of febrile response to IL-1β  Academic Article
• Ceramide triggers budding of exosome vesicles into multivesicular endosomes  Academic Article
• Cerebellar granule neurons develop elevated calcium responses when treated with interleukin-6 in culture  Academic Article
• Cerebellar lipid differences between r6/1 transgenic mice and humans with huntington's disease  Academic Article
• Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis  Academic Article
• Cerebrospinal fluid amyloid-beta (A beta) as an effect biomarker for brain A beta lowering verified by quantitative preclinical analyses  Academic Article
• Change in susceptibility of c3h-hej mice to lcm virus-infection  Academic Article
• Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse  Academic Article
• Changes in striatal signaling induce remodeling of RGS complexes containing G beta 5 and R7BP subunits  Academic Article
• Changes in the cytoplasmic structure of ctls during target cell recognition and killing  Academic Article
• Changes in the extent of microtubule assembly can regulate initiation of DNA-synthesis  Academic Article
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• Characteristics of immunity induced by viral antigen or conferred by antibody via different administration routes  Academic Article
• Characterization and TCR variable region gene use of mouse resident nasal gamma delta T lymphocytes  Academic Article
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• Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas  Academic Article
• Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture  Academic Article
• Characterization of H7N9 influenza A viruses isolated from humans  Academic Article
• Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis  Academic Article
• Characterization of TCR gene rearrangements during adult murine T cell development  Academic Article
• Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.  Academic Article
• Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo  Academic Article
• Characterization of a membrane-surface glycoprotein associated with t-cell activation  Academic Article
• Characterization of a neuronal interleukin-1 receptor and the corresponding mRNA in the mouse anterior pituitary cell line AtT-20  Academic Article
• Characterization of a side population of astrocytoma cells in response to temozolomide  Academic Article
• Characterization of a type-common human recombinant monoclonal antibody to herpes simplex virus with high therapeutic potential  Academic Article
• Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance  Academic Article
• Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity  Academic Article
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• Characterization of an ig v-h idiotope that results in specific homophilic binding and increased avidity for antigen  Academic Article
• Characterization of antibody responses to purified hiv-1 gp120 glycoproteins fused with the molecular adjuvant c3d  Academic Article
• Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice  Academic Article
• Characterization of highper, an enu-induced mouse mutant with abnormal psychostimulant and stress responses  Academic Article
• Characterization of ia antigens in mouse serum  Academic Article
• Characterization of immature CD4+CD8-CD3- thymocytes  Academic Article
• Characterization of lpa(2) (edg4) and lpa(1)/lpa(2) (edg2/edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)  Academic Article
• Characterization of lymphocytic choriomeningitis virus-binding protein(s) - a candidate cellular receptor for the virus  Academic Article
• Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection  Academic Article
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• Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism  Academic Article
• Characterization of monoclonal-antibody 155.8 and partial characterization of its proteoglycan antigen on human-melanoma cells  Academic Article
• Characterization of mouse mutants with abnormal RPE cells  Academic Article
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• Characterization of murine a-raf, a new oncogene related to the v-raf oncogene  Academic Article
• Characterization of murine cytolytic-helper hybrid t-cell clones  Academic Article
• Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo  Academic Article
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• Characterization of reciprocal MRL-Fas(lpr) and C57BL/6-Fas(lpr) congenic mice reveals significant effects from Lmb3  Academic Article
• Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro  Academic Article
• Characterization of splenic lymphoid cells in fetal and newborn mice  Academic Article
• Characterization of stem cell-like cancer cells in immune-competent mice  Academic Article
• Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands  Academic Article
• Characterization of the early stages of thymic NKT cell development  Academic Article
• Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study  Academic Article
• Characterization of the first potent and selective PDE9 inhibitor using a cGMP reporter cell line  Academic Article
• Characterization of the inflammatory response during acute measles encephalitis in nse-cd46 transgenic mice  Academic Article
• Characterization of the murine antigenic determinant, designated l3t4a, recognized by monoclonal-antibody gk1.5 - expression of l3t4a by functional t-cell clones appears to correlate primarily with class ii mhc antigen-reactivity  Academic Article
• Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase  Academic Article
• Characterization of the transformation-specific sequences of avian erythroblastosis virus in normal vertebrate cells  Academic Article
• Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases  Academic Article
• Characterization of two monoclonal antibodies against human tissue-type plasminogen activator  Academic Article
• Characterization of vascular adhesion molecules that may facilitate progenitor homing in the post-natal mouse thymus  Academic Article
• Characterization, design, and function of the mitochondrial proteome: from organs to organisms  Academic Article
• Characterization, serological specificity, and diagnostic possibilities of monoclonal-antibodies against legionella-pneumophila  Academic Article
• Characterizing the composition of molecular motors on moving axonal cargo using "cargo mapping" analysis  Academic Article
• Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis  Academic Article
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• Charcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levels  Academic Article
• Checkpoints in memory b-cell evolution  Academic Article
• Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens  Academic Article
• Chemical activation of the mechanotransduction channel Piezo1  Academic Article
• Chemical and biological investigations of β-oligoarginines  Academic Article
• Chemical and mutagenic investigations of fatty acid amide hydrolase: Evidence for a family of serine hydrolases with distinct catalytic properties  Academic Article
• Chemical dissection of mammalian spermatozoa  Academic Article
• Chemical dissection of mammalian spermatozoa  Academic Article
• Chemical generation of bispecific antibodies  Academic Article
• Chemical genetics of Plasmodium falciparum  Academic Article
• Chemical markers of transplantation individuality solubilized with sonic energy  Academic Article
• Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes  Academic Article
• Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing  Academic Article
• Chemical proteomic probes for profiling cytochrome P450 activities and drug interactions in vivo  Academic Article
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• Chemical strategies for stem cell biology and regenerative medicine  Academic Article
• Chemical synthesis of idiotopes - evidence that antisera to the same jh1 peptide detect multiple binding site-associated idiotopes  Academic Article
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• Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes  Academic Article
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• Chlorosulfolipids: structure, synthesis, and biological relevance  Academic Article
• Chlorotoxin-mediated disinhibition of noradrenergic locus coeruleus neurons using a conditional transgenic approach  Academic Article
• Chmp5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis  Academic Article
• Cholecystokinin dipeptoid antagonists: Design, synthesis, and anxiolytic profile of some novel cck-a and cck-b selective and "mixed" cck-a/cck-b antagonists  Academic Article
• Cholera toxin subunit B peptide fusion proteins reveal impaired oral tolerance induction in diabetes-prone but not in diabetes-resistant mice  Academic Article
• Cholesterol secosterol adduction inhibits the misfolding of a mutant prion protein fragment that induces neurodegeneration  Academic Article
• Cholesteryl ester hydrolase activity is abolished in HSL(-/-) macrophages but unchanged in macrophages lacking KIAA1363  Academic Article
• Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice  Academic Article
• Chromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genes  Academic Article
• Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway  Academic Article
• Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB  Academic Article
• Chromosomal integration dependent induction of junb by growth factors requires multiple flanking evolutionarily conserved sequences  Academic Article
• Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi  Academic Article
• Chromosomal location of a human alpha-interferon gene family  Academic Article
• Chromosomal location of the gene encoding the neural cell-adhesion molecule (n-cam) in the mouse  Academic Article
• Chromosomal mapping of mouse genes expressed selectively within the central-nervous-system  Academic Article
• Chromosomal mosaicism in neural stem cells  Academic Article
• Chromosomal variation in neurons of the developing and adult mammalian nervous system  Academic Article
• Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells  Academic Article
• Chromosome transfer activates and delineates a locus control region for perforin  Academic Article
• Chromosome-14 in b10.A(18r) mice is recombinant and includes tcra-va alleles  Academic Article
• Chronic cerebral hypoxia promotes arteriogenic remodeling events that can be identified by reduced endoglin (CD105) expression and a switch in beta 1 integrins  Academic Article
• Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration  Academic Article
• Chronic haloperidol treatment results in a decrease in the expression of myelin/oligodendrocyte-related genes in the mouse brain  Academic Article
• Chronic immobilization in the malpar1 knockout mice increases oxidative stress in the hippocampus  Academic Article
• Chronic interleukin-6 alters the level of synaptic proteins in hippocampus in culture and in vivo  Academic Article
• Chronic lymphocytic inflammation specifies the organ tropism of prions  Academic Article
• Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system  Academic Article
• Chronic morphine induces premature mitosis of proliferating cells in the adult mouse subgranular zone  Academic Article
• Chronic virus-infection and immune responsiveness .2. Lactic-dehydrogenase virus-infection and immune-response to non-viral antigens  Academic Article
• Chronic wasting disease of deer and elk in transgenic mice: Oral transmission and pathobiology  Academic Article
• Cipc is a mammalian circadian clock protein without invertebrate homologues  Academic Article
• Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation  Academic Article
• Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines  Academic Article
• Circadian control of global gene expression patterns  Academic Article
• Circadian light input in plants, flies and mammals  Academic Article
• Circadian oscillations of protein-coding and regulatory RNAs in a highly dynamic mammalian liver epigenome  Academic Article
• Circadian rhythm genetics: from flies to mice to humans  Academic Article
• Circadian rhythms. As time PASses: the first mammalian clock gene  Academic Article
• Circadian timing of ethanol exposure exerts enduring effects on subsequent ad libitum consumption in c57 mice  Academic Article
• Circadian transcriptional output in the SCN and liver of the mouse  Academic Article
• Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling  Academic Article
• Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein  Academic Article
• Citation Classic: A requirement for two cell types for antibody formation in vitro  Academic Article
• Citrullination of proteins: A common post-translational modification pathway induced by different nanoparticles in vitro and in vivo  Academic Article
• Citrullination regulates pluripotency and histone H1 binding to chromatin  Academic Article
• Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints  Academic Article
• Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo  Academic Article
• Class switch recombination and somatic hypermutation in early mouse b cells are mediated by b cell and toll-like receptors  Academic Article
• Class-i mhc can present an endogenous peptide to cyto-toxic lymphocytes-t  Academic Article
• Class-switched memory B cells remodel BCRs within secondary germinal centers  Academic Article
• Classification of PDZ domains  Academic Article
• Clathrate nanostructures for mass spectrometry  Academic Article
• Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs  Academic Article
• Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice  Academic Article
• Cleavage of p65/re1a of the nf-kappa b pathway by chlamydia  Academic Article
• Clec5a is critical for dengue-virus-induced lethal disease  Academic Article
• Click and pick: identification of sialoside analogues for siglec-based cell targeting  Academic Article
• Click chemistry in situ: Acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks  Academic Article
• Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors  Academic Article
• Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis  Academic Article
• Clinical isolates of measles virus use cd46 as a cellular receptor?  Academic Article
• Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase  Academic Article
• Clonal analysis of autoantibody-producing cell precursors in the preimmune b-cell repertoire  Academic Article
• Clonal analysis of cd4+ t-helper cell subsets that induce the monocyte procoagulant response  Academic Article
• Clonal analysis of mechanisms of murine t-helper cell collaboration with effector-cells of macrophage lineage  Academic Article
• Clonal analysis of primary marrow stroma: functional homogeneity in support of lymphoid and myeloid cell lines and identification of positive and negative regulators  Academic Article
• Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses  Academic Article
• Clonal deletion of autoreactive lymphocytes-b in bone-marrow chimeras  Academic Article
• Clonal deletion of autospecific lymphocytes-b  Academic Article
• Clonal deletion of lymphocyte-b in a transgenic mouse bearing anti-mhc class-i antibody genes  Academic Article
• Clonal diversity and t-cell receptor beta-chain variable gene-expression in enlarged lymph-nodes of mrl-lpr-lpr lupus mice  Academic Article
• Clonal heterogeneity of the anti-erythrocyte autoantibody responses of NZB mice  Academic Article
• Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing  Academic Article
• Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties  Academic Article
• Cloned cytotoxic T lymphocytes as target cells. II. Polarity of lysis revisited  Academic Article
• Cloned human CD8+ cytotoxic T lymphocytes protect human peripheral blood leukocyte-severe combined immunodeficient mice from HIV-1 infection by an HLA-unrestricted mechanism  Academic Article
• Clonidine blocks acquisition but not expression of conditioned opiate withdrawal in rats  Academic Article
• Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors  Academic Article
• Cloning and characterization of a sub-family of human toll-like receptors: Htlr7, htlr8 and htlr9  Academic Article
• Cloning and characterization of cDNAs encoding 2,3,7,8-tetrachlorodibenzo-para-dioxin-inducible rabbit messenger-RNAs for cytochrome-P-450 isozyme-4 and isozyme-6  Academic Article
• Cloning and characterization of cyclophilin c-associated protein - a candidate natural cellular ligand for cyclophilin-c  Academic Article
• Cloning and characterization of mouse GABA(C) receptor subunits  Academic Article
• Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4  Academic Article
• Cloning and expression of 3 rabbit kidney cDNAs encoding lauric acid omega-hydroxylases  Academic Article
• Cloning and nucleotide-sequence of mouse immunoglobulin epsilon-chain cdna  Academic Article
• Cloning and overexpression of rhamnose isomerase and fucose isomerase  Academic Article
• Cloning and sequencing of cDNA encoding mouse cytohesin-1  Academic Article
• Cloning and sequencing of the murine homolog of the human splicing factor u2af(65)  Academic Article
• Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein e-deficient mice - demonstration of epitopes of oxidized low density lipoprotein in human plasma  Academic Article
• Cloning of murine stat6 and human stat6, stat proteins that are tyrosine-phosphorylated in responses to il-4 and il-3 but are not required for mitogenesis  Academic Article
• Cloning of the immunological repertoire in escherichia-coli for generation of monoclonal catalytic antibodies - construction of a heavy-chain variable region-specific cDNA library  Academic Article
• Cloning of the murine platelet glycoprotein Ib alpha gene highlighting species-specific platelet adhesion  Academic Article
• Cloning, expression, and characterization of chicken tissue inhibitor of metalloproteinase-2 (timp-2) in normal and transformed chicken embryo fibroblasts  Academic Article
• Cloning, mrna expression, and chromosomal mapping of mouse and human preprocortistatin  Academic Article
• Close homolog of l1 and neuropilin 1 mediate guidance of thalamocortical axons at the ventral telencephalon  Academic Article
• Clozapine increases apolipoprotein d expression in rodent brain: Towards a mechanism for neuroleptic pharmacotherapy  Academic Article
• Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein d  Academic Article
• Cluster analysis of aminoacyl-tRNAs from mouse plasmacytomas correlates chromatographic profiles with myeloma protein similarity, clonal origin of tumour lines, and the neoplastic nature of the tissues  Academic Article
• Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: Studies with the model tumor antigen beta-galactosidase and the BALB/c Meth A p53 tumor-specific antigen  Academic Article
• Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain  Academic Article
• Co-inoculation of human and murine carcinoma cells induces reciprocal suppression of metastasis by both cell lines  Academic Article
• Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice  Academic Article
• Cocaine analog coupled to disrupted adenovirus: A vaccine strategy to evoke high-titer immunity against addictive drugs  Academic Article
• Cocaine catalytic antibodies: The primary importance of linker effects  Academic Article
• Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide  Academic Article
• Coding end processing is similar throughout ontogeny  Academic Article
• Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways  Academic Article
• Coding sequence polymorphisms among v-beta t-cell receptor genes  Academic Article
• Coexpression of b7-1 and viral (''self'') transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes  Academic Article
• Coexpression of δ- and μ-opioid receptors in nociceptive sensory neurons  Academic Article
• Cohesin-mediated interactions organize chromosomal domain architecture  Academic Article
• Cold stress-induced protein rbm3 binds 60s ribosomal subunits, alters rnicrorna levels, and enhances global protein synthesis  Academic Article
• Collagenolysis-dependent angiogenesis mediated by matrix metalloproteinase-13 (collagenase-3)  Academic Article
• Coloboma hyperactive mutant mice exhibit regional and transmitter-specific deficits in neurotransmission  Academic Article
• Colocalization of a CD1d-binding glycolipid with a radiation-attenuated sporozoite vaccine in lymph node-resident dendritic cells for a robust adjuvant effect  Academic Article
• Combination angiostatic therapies: targeting multiple angiogenic pathways  Academic Article
• Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Academic Article
• Combination of anti-HER3 antibody MM-121/SAR256212 and cetuximab inhibits tumor growth in preclinical models of head and neck squamous cell carcinoma  Academic Article
• Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model  Academic Article
• Combination of methamphetamine and HIV-1 gp120 causes distinct long-term alterations of behavior, gene expression, and injury in the central nervous system  Academic Article
• Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma  Academic Article
• Combinational diversity within variable regions bearing the predominant anti-rho-azophenylarsonate idiotype of strain-a mice  Academic Article
• Combinations of interleukins 2, 4 and 5 regulate the secretion of murine immunoglobulin isotypes  Academic Article
• Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis  Academic Article
• Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma  Academic Article
• Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation  Academic Article
• Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models  Academic Article
• Combined pseudo-merohedral twinning, non-crystallographic symmetry and pseudo-translation in a monoclinic crystal form of the gamma delta t-cell ligand t10  Academic Article
• Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer  Academic Article
• Combining cross-metathesis and activity-based protein profiling: New beta-lactone motifs for targeting serine hydrolases  Academic Article
• Combining metabolite-based pharmacophores with Bayesian machine learning models for mycobacterium tuberculosis drug discovery  Academic Article
• Combining phage display with de novo protein sequencing for reverse engineering of monoclonal antibodies  Academic Article
• Commensal bacteria make GPCR ligands that mimic human signalling molecules  Academic Article
• Commitment issues: linking positive selection signals and lineage diversification in the thymus  Academic Article
• Commitment to the T-cell receptor-alpha-beta or receptor-gamma-delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes  Academic Article
• Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery  Academic Article
• Common and idiosyncratic patterns of cytokine gene expression by Epstein-Barr virus transformed human B cell lines  Academic Article
• Common antiviral cytotoxic t-lymphocyte epitope for diverse arenaviruses  Academic Article
• Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension  Academic Article
• Common immunological determinant between human-immunodeficiency-virus type-1 gp41 and astrocytes  Academic Article
• Common membrane trafficking defects of disease-associated dynamin 2 mutations  Academic Article
• Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72  Academic Article
• Comoviruses and enteroviruses share a t-cell epitope  Academic Article
• Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation  Academic Article
• Comparative analysis of antitumor activity of CD40L, RANKL, and 4-1BBL in vivo following intratumoral administration of viral vectors or transduced dendritic cells  Academic Article
• Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: sensitivity to tumor-induced apoptosis  Academic Article
• Comparative analysis of fatty acid amide hydrolase and cb1 cannabinoid receptor expression in the mouse brain: Evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling  Academic Article
• Comparative analysis of haplotype association mapping algorithms  Academic Article
• Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion  Academic Article
• Comparative analysis of three murine g-protein coupled receptors activated by sphingosine-1-phosphate  Academic Article
• Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: Identification of the transmembrane domain as a site for oligomerization  Academic Article
• Comparative effects of neonatal diethylstilbestrol on external genitalia development in adult males of two mouse strains with differential estrogen sensitivity  Academic Article
• Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian h5n1 influenza virus  Academic Article
• Comparative epitope mapping of murine monoclonal and human autoantibodies to human pdh-e2, the major mitochondrial autoantigen of primary biliary-cirrhosis  Academic Article
• Comparative expression of TNF-alpha alleles from normal and autoimmune-prone MHC haplotypes  Academic Article
• Comparative immunological analysis of several murine strains with autoimmune manifestations  Academic Article
• Comparative proteome analysis using amine-reactive isobaric tagging reagents coupled with 2D LC/MS/MS in 3T3-L1 adipocytes following hypoxia or normoxia  Academic Article
• Comparative studies of the fibrinolytic activity of cultured vascular cells  Academic Article
• Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus  Academic Article
• Comparison of anandamide transport in FAAH wild-type and knockout neurons: Evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake  Academic Article
• Comparison of binding characteristics of endothelin receptors on subpopulations of astrocytes  Academic Article
• Comparison of biochemical and biological properties of standard and defective lymphocytic choriomeningitis virus  Academic Article
• Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of 2 homologous pairs of introns  Academic Article
• Comparison of g-protein activation in the brain by mu-, delta-, and kappa-opioid receptor agonists in mu-opioid receptor knockout mice  Academic Article
• Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells  Academic Article
• Comparison of junctional diversity in the neonatal and adult immunoglobulin repertoires  Academic Article
• Comparison of mice with accelerated aging caused by distinct mechanisms  Academic Article
• Comparison of the H-2Kb-specific cytolytic T lymphocyte receptor repertoire in Igh recombinant strains  Academic Article
• Comparison of the activity of doxorubicin analogs using colony-forming assays and human xenografts  Academic Article
• Comparison of the antitumor efficacies of Her-2/neu DNA vaccines inducing contrasting IgG immunity but comparable CTL activity in mice  Academic Article
• Comparison of the effects of the GABA(B) receptor positive modulator BHF177 and the GABA(B) receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice  Academic Article
• Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence  Academic Article
• Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis  Academic Article
• Compensatory redistribution of neuroligins and N-cadherin following deletion of synaptic β1-integrin  Academic Article
• Competition between bactericidal permeability-increasing protein and lipopolysaccharide-binding protein for lipopolysaccharide binding to monocytes  Academic Article
• Competitive selection in vivo by a cell for one variant over another: Implications for rna virus quasispecies in vivo  Academic Article
• Complete amino-acid-sequence and maturation of the mouse sub-maxillary gland renin precursor  Academic Article
• Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, vzg-1/lpA1/Gpcr26.  Academic Article
• Complete primary structure of porcine tenascin - detection of tenascin transcripts in adult submaxillary-glands  Academic Article
• Completion of the entire hepatitis C virus life cycle in genetically humanized mice  Academic Article
• Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci  Academic Article
• Complex of a protective antibody with its ebola virus gp peptide epitope: Unusual features of a v lambda(x) light chain  Academic Article
• Complex regulation of tumor-necrosis-factor messenger-rna turnover in lipopolysaccharide-activated macrophages  Academic Article
• Complexin controls the force transfer from SNARE complexes to membranes in fusion  Academic Article
• Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression  Academic Article
• Computer-assisted analysis of in vivo cytotoxic T cell responses  Academic Article
• Concanavalin a derivatives with altered biological activities  Academic Article
• Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action  Academic Article
• Concise review: A chemical approach to control cell fate and function  Academic Article
• Concomitant differentiation of a population of mouse embryonic stem cells into neuron-like cells and schwann cell-like cells in a slow-flow microfluidic device  Academic Article
• Conditional HIF-1α expression produces a reversible cardiomyopathy  Academic Article
• Conditional disruption of beta 1 integrin in schwann cells impedes interactions with axons  Academic Article
• Conditional knockout of integrin alpha 2 beta 1 in murine megakaryocytes leads to reduced mean platelet volume  Academic Article
• Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes  Academic Article
• Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity  Academic Article
• Conformational epitope mapping of antibodies against desmoglein 3 in experimental murine pemphigus vulgaris  Academic Article
• Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and folding  Academic Article
• Conformationally-restricted arginine analogues as alternative substrates and inhibitors of nitric oxide syntheses  Academic Article
• Conjugation of functionalized gadolinium metallofullerenes with IL-13 peptides for targeting and imaging glial tumors  Academic Article
• Connections between connexins, calcium, and cataracts in the lens  Academic Article
• Connexin 50 regulates surface ball-and-socket structures and fiber cell organization  Academic Article
• Connexin mediated cataract prevention in mice  Academic Article
• Consensus M2e peptide conjugated to gold nanoparticles confers protection against H1N1, H3N2 and H5N1 influenza A viruses  Academic Article
• Consequences of cytotoxic T lymphocyte interaction with major histocompatibility complex class I-expressing neurons in vivo  Academic Article
• Consequences of secondary or coinfections for immunity  Academic Article
• Consequences of self-presentation of peptide antigen by cytolytic T lymphocytes  Academic Article
• Conservation of tissue factor primary sequence among 3 mammalian-species  Academic Article
• Conserved amino acid residues in the complementarity-determining region 1 of the TCR β-chain are involved in the recognition of conventional Ag and Mls-1 superantigen  Academic Article
• Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors  Academic Article
• Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation  Academic Article
• Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals  Academic Article
• Conserved structures of mediator and RNA polymerase II holoenzyme  Academic Article
• Consolidation of learning strategies during spatial working memory task requires protein synthesis in the prefrontal cortex  Academic Article
• Constant flow-driven microfluidic oscillator for different duty cycles  Academic Article
• Constitutive activity of the melanocortin-4 receptor is maintained by its n-terminal domain and plays a role in energy homeostasis in humans  Academic Article
• Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect  Academic Article
• Constitutive and LPS-regulated expression of interleukin-18 receptor beta variants in the mouse brain  Academic Article
• Constitutive beta cell expression of il-12 does not perturb self-tolerance but intensifies established autoimmune diabetes  Academic Article
• Constitutive expression of murine decay-accelerating factor 1 is controlled by the transcription factor sp1  Academic Article
• Constitutive synthesis of tumor necrosis factor in the thymus  Academic Article
• Constitutive systemic expression of il-1ra or soluble tnf receptor by genetically modified hematopoietic cells suppresses lps induction of il-6 and il-10  Academic Article
• Constitutively unmasked cd22 on b cells of st6gal i knockout mice: Novel sialoside probe for murine cd22  Academic Article
• Construction and characterization of retroviral vectors expressing biologically active human interleukin-12  Academic Article
• Construction and screening of a genomic library specific for mouse chromosome-16  Academic Article
• Construction of epithelioid sheets by transfection of mouse sarcoma-cells with cdnas for chicken-cell adhesion molecules  Academic Article
• Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody  Academic Article
• Contrasting IgG structures reveal extreme asymmetry and flexibility  Academic Article
• Contribution of LCMV towards deciphering biology of quasispecies in vivo  Academic Article
• Contribution of TCR signaling strength to CD8(+) T cell peripheral tolerance mechanisms  Academic Article
• Contribution of leptin receptor N-linked glycans to leptin binding  Academic Article
• Contribution of lipopolysaccharide binding protein (LBP) in endotoxemic shock in mice  Academic Article
• Contribution of receptor editing to the antibody repertoire  Academic Article
• Contribution of spinal 5-ht1a and 5-ht7 receptors to locomotor-like movement induced by 8-oh-dpat in spinal cord-transected mice  Academic Article
• Contributions of individual nucleotides to tertiary binding of substrate by a Pneumocystis carinii group I intron  Academic Article
• Contributions of neuronal prion protein on sleep recovery and stress response following sleep deprivation  Academic Article
• Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice  Academic Article
• Control of b cell production by the adaptor protein lnk: Definition of a conserved family of signal-modulating proteins  Academic Article
• Control of cachectin (tumor-necrosis-factor) synthesis - mechanisms of endotoxin resistance  Academic Article
• Control of cortical interneuron migration by neurotrophins and pi3-kinase signaling  Academic Article
• Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors  Academic Article
• Control of growth by the somatropic axis: Growth hormone and the insulin-like growth factors have related and independent roles  Academic Article
• Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition  Academic Article
• Control of memory CD4 T cell recall by the CD28/B7 costimulatory pathway  Academic Article
• Control of memory formation through regulated expression of a camkii transgene  Academic Article
• Control of mhc restriction by tcr v-alpha cdr1 and cdr2  Academic Article
• Control of spine maturation and pruning through proBDNF synthesized and released in dendrites  Academic Article
• Control of the exo-pathway and endo-pathway of the Diels-Alder reaction by antibody catalysis  Academic Article
• Control of the murine phosphofructokinase-a gene during muscle differentiation  Academic Article
• Controlled transcription of a human alpha-interferon gene introduced into mouse l-cells  Academic Article
• Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: Targeting the RNAs that cause myotonic muscular dystrophy  Academic Article
• Convergence of itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation  Academic Article
• Convergent functional genomic studies of omega-3 fatty acids in stress reactivity, bipolar disorder and alcoholism  Academic Article
• Convergent functional genomics of anxiety disorders: Translational identification of genes, biomarkers, pathways and mechanisms  Academic Article
• Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms  Academic Article
• Convergent functional genomics: application to bipolar disorder  Academic Article
• Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system  Academic Article
• Conversion of embryonic form to adult forms of n-cam in vitro - results from denovo synthesis of adult forms  Academic Article
• Conversion of human fibroblasts into functional cardiomyocytes by small molecules  Academic Article
• Conversion of human fibroblasts to angioblast-like progenitor cells  Academic Article
• Conversion of human fibroblasts to functional endothelial cells by defined factors  Academic Article
• Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules  Academic Article
• Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy  Academic Article
• Conversion of non-adipogenic fibroblasts into adipocytes by a defined hormone mixture  Academic Article
• Converting IL-15 to a superagonist by binding to soluble IL-15R alpha  Academic Article
• Converting mouse epiblast stem cells into mouse embryonic stem cells by using small molecules  Academic Article
• Convulxin binds to native, human glycoprotein IIbα  Academic Article
• Cooperation between VEGF and beta 3 integrin during cardiac vascular development  Academic Article
• Cooperation between both Wnt/β-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion  Academic Article
• Cooperation of human tumor-reactive CD4+ and CD8+ T cells after redirection of their specificity by a high-affinity p53A2.1-specific TCR  Academic Article
• Cooperation of tissue factor cytoplasmic domain and par2 signaling in breast cancer development  Academic Article
• Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment  Academic Article
• Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis  Academic Article
• Cooperative regulation of p53 by modulation of ternary complex formation with cbp/p300 and hdm2  Academic Article
• Cooperativity enables non-neutralizing antibodies to neutralize Ebolavirus  Academic Article
• Cooperativity in transcription factor binding to the coactivator creb-binding protein (cbp) - the mixed lineage leukemia protein (mll) activation domain binds to an allosteric site on the kix domain  Academic Article
• Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition  Academic Article
• Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence  Academic Article
• Coordinated transcription of key pathways in the mouse by the circadian clock  Academic Article
• Coordination of Rho GTPase activities during cell protrusion  Academic Article
• Copper refolding of prion protein  Academic Article
• Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22  Academic Article
• Core transcriptional regulatory circuitry in human embryonic stem cells  Academic Article
• Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC  Academic Article
• Coronin promotes the rapid assembly and cross-linking of actin filaments and may link the actin and microtubule cytoskeletons in yeast  Academic Article
• Correction of RT-qPCR data for genomic DNA-derived signals with ValidPrime  Academic Article
• Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model  Academic Article
• Corrugoside, a new immunostimulatory alpha-galactoglycosphingolipid from the marine sponge Axinella corrugata  Academic Article
• Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB  Academic Article
• Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital, and diazepam in mice  Academic Article
• Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development  Academic Article
• Corticotropin-releasing factor receptor-2-deficient mice display abnormal homeostatic responses to challenges of increased dietary fat and cold  Academic Article
• Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior  Academic Article
• Cortistatin and somatostatin mrnas are differentially regulated in response to kainate  Academic Article
• Cortistatin overexpression in transgenic mice produces deficits in synaptic plasticity and learning  Academic Article
• Costimulation modulation uncouples protection from immunopathology in memory T cell responses to influenza virus  Academic Article
• Costimulation requirements of induced murine systemic autoimmune disease  Academic Article
• Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection  Academic Article
• Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in c57bl/6j mice  Academic Article
• Coupling of the adhesive receptor cd11b/cd18 to functional enhancement of effector macrophage tissue factor response  Academic Article
• Cowpea mosaic virus capsid: a promising carrier for the development of carbohydrate based antitumor vaccines  Academic Article
• Cox-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation  Academic Article
• Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers  Academic Article
• Coxsackievirus B3 infects the bone marrow and diminishes the restorative capacity of erythroid and lymphoid progenitors  Academic Article
• Coxsackievirus b3 and the neonatal cns - the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease  Academic Article
• Coxsackievirus b3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the mhc class i pathway  Academic Article
• Coxsackievirus b3-induced myocarditis - perforin exacerbates disease, but plays no detectable role in virus clearance  Academic Article
• Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo  Academic Article
• Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo  Academic Article
• Coxsackievirus infection of the pancreas: Evaluation of receptor expression, pathogenesis, and immunopathology  Academic Article
• Coxsackievirus preferentially replicates and induces cytopathic effects in undifferentiated neural progenitor cells  Academic Article
• Coxsackievirus replication and the cell cycle: A potential regulatory mechanism for viral persistence/latency  Academic Article
• Coxsackievirus targets proliferating neuronal progenitor cells in the neonatal CNS  Academic Article
• Cre recombinase-mediated gene deletion in layer 4 of murine sensory cortical areas  Academic Article
• Creb coactivators direct anabolic responses and enhance performance of skeletal muscle  Academic Article
• Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity  Academic Article
• Critical evaluation of bispecific antibodies as targetins agents for boron neutron capture therapy of brain tumors  Academic Article
• Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus  Academic Article
• Critical role for glucocorticoid receptors in stress-induced and ethanol-induced locomotor sensitization  Academic Article
• Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses  Academic Article
• Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response  Academic Article
• Critical role of transmethylation in TLR signaling and systemic lupus erythematosus  Academic Article
• Cross-linking cellular prion protein triggers neuronal apoptosis in vivo  Academic Article
• Cross-linking of lipopolysaccharide (lps) to cd14 on thp-1 cells mediated by lps-binding protein  Academic Article
• Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein  Academic Article
• Cross-neutralization of influenza a viruses mediated by a single antibody loop  Academic Article
• Cross-reactive and potent neutralizing antibody responses in human survivors of natural Ebolavirus infection  Academic Article
• Cross-reactivity between hl-a and h-2 antigens. Ii. Allogeneic sensitization by xenogeneic soluble lymphocyte antigens (hl-a)  Academic Article
• Crosses of nod mice with the related non strain - a polygenic model for iddm  Academic Article
• Cryo-em visualization of an exposed rgd epitope on adenovirus that escapes antibody neutralization  Academic Article
• Cryopreservation by slow cooling with dmso diminished production of oct-4 pluripotency marker in human embryonic stem cells  Academic Article
• Cryopreservation of cancer-initiating cells derived from glioblastoma  Academic Article
• Cryopreservation of neurospheres derived from human glioblastoma multiforme  Academic Article
• Cryptic epitopes in n-terminally truncated prion protein are exposed in the full-length molecule: Dependence of conformation on ph  Academic Article
• Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis  Academic Article
• Cryptochromes mediate rhythmic repression of the glucocorticoid receptor  Academic Article
• Cryptochromes: bringing the blues to circadian rhythms  Academic Article
• Crystal structure determination of anti-DNA Fab A52  Academic Article
• Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif  Academic Article
• Crystal structure of NMC-4 fab anti-von Willebrand factor A1 domain  Academic Article
• Crystal structure of a cocaine-binding antibody  Academic Article
• Crystal structure of a conserved hypothetical protein (gi : 13879369) from Mouse at 1.90 A resolution reveals a new fold  Academic Article
• Crystal structure of a gamma delta t cell receptor ligand t22: A truncated mhc-like fold  Academic Article
• Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design  Academic Article
• Crystal structure of a putative NADPH-dependent oxidoreductase (GI : 18204011) from mouse at 2.10 Å resolution  Academic Article
• Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 a resolution  Academic Article
• Crystal structure of adenosine 5 '-phosphosulfate kinase from Penicillium chrysogenum  Academic Article
• Crystal structure of an Apo mRNA decapping enzyme (DcpS) from mouse at 1.83 Å resolution  Academic Article
• Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor  Academic Article
• Crystal structure of an mhc class i presented glycopeptide that generates carbohydrate-specific ctl  Academic Article
• Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove  Academic Article
• Crystal structure of mouse cd1d bound to the self ligand phosphatidylcholine: A molecular basis for nkt cell activation  Academic Article
• Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (trem-1) at 1.76 Å  Academic Article
• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser  Academic Article
• Crystal structure of the C-terminal domain of mouse TLR9  Academic Article
• Crystal structure of the TCR co-receptor CD8 alpha alpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution  Academic Article
• Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide  Academic Article
• Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran  Academic Article
• Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding  Academic Article
• Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A  Academic Article
• Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of camp-dependent protein kinase  Academic Article
• Crystal structures of mouse CD1d-iGb3 complex and its cognate v alpha 14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids  Academic Article
• Crystal structures of two I-A(d)-peptide complexes reveal that high affinity can be achieved without large anchor residues  Academic Article
• Crystal-structure of a human-immunodeficiency-virus type-1 neutralizing antibody, 50.1, in complex with its v3 loop peptide antigen  Academic Article
• Crystal-structure of an h-2k(b)-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove  Academic Article
• Crystal-structure of murine cyclophilin-c complexed with immunosuppressive drug cyclosporine-a  Academic Article
• Crystal-structures of 2 viral peptides in complex with murine mhc class-i h-2k(b)  Academic Article
• Crystallin gamma B-I4F mutant protein binds to alpha-crystallin and affects lens transparency  Academic Article
• Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition-state analog  Academic Article
• Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides  Academic Article
• Crystallization, sequence, and preliminary crystallographic data for an antipeptide-fab-50.1 and peptide complexes with the principal neutralizing determinant of hiv-1 gp120  Academic Article
• Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization  Academic Article
• Ctl escape viral variants .1. Generation and molecular characterization  Academic Article
• Cultured astrocytes release a factor that decreases endothelin-1 secretion by brain microvessel endothelial-cells  Academic Article
• Cultures of astrocytes and microglia express interleukin 18  Academic Article
• Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient  Academic Article
• Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function  Academic Article
• Cutting edge: Developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development  Academic Article
• Cutting edge: Early ifn-gamma signaling directly enhances primary antivliwal cd4(+) t cell responses  Academic Article
• Cutting edge: IL-13Rα1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide  Academic Article
• Cutting edge: Impaired glycosphingolipid trafficking and NKT cell development in mice lacking Niemann-Pick type C1 protein  Academic Article
• Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver  Academic Article
• Cutting edge: Lack of high affinity competition for peptide in polyclonal cd4(+) responses unmasks il-4 production  Academic Article
• Cutting edge: Priming of NK cells by IL-18  Academic Article
• Cutting edge: Recent immune status determines the source of antigens that drive homeostatic t cell expansion  Academic Article
• Cutting edge: The tyrosine phosphatase SHP-1 regulates thymocyte positive selection  Academic Article
• Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection  Academic Article
• Cutting edge: Trimolecular interaction of tcr with mhc class ii and bacterial superantigen shows a similar affinity to mhc : Peptide ligands  Academic Article
• Cutting edge: dendritic epidermal gamma delta T cell ligands are rapidly and locally expressed by keratinocytes following cutaneous wounding  Academic Article
• Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect  Academic Article
• Cyclic regulation of sensory perception by a female hormone alters behavior  Academic Article
• Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients  Academic Article
• Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcription  Academic Article
• Cyclin D3 maintains growth-inhibitory activity of C/EBPalpha by stabilizing C/EBPalpha-cdk2 and C/EBPalpha-Brm complexes  Academic Article
• Cyclin e-induced s phase without activation of the prb/e2f pathway  Academic Article
• Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities  Academic Article
• Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins  Academic Article
• Cyclin-dependent kinase-associated proteins cks1 and cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells  Academic Article
• Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity  Academic Article
• Cyclooxygenase-2: Where are we in 2003? Cardiovascular risk and cox-2 inhibitors  Academic Article
• Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex  Academic Article
• Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?  Academic Article
• Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception  Academic Article
• Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A  Academic Article
• Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile  Academic Article
• Cytogenetic characterization of B-cell lymphomas from severe combined immunodeficiency disease mice given injections of lymphocytes from Epstein-Barr virus-positive donors  Academic Article
• Cytoimmunotherapy for persistent virus-infection reveals a unique clearance pattern from the central-nervous-system  Academic Article
• Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials  Academic Article
• Cytokine gene-therapy with interleukin-2-transduced fibroblasts - effects of il-2 dose on antitumor immunity  Academic Article
• Cytokine regulation of TNF-alpha mRNA and protein production by unprimed macrophages from C57Bl/6 and NZW mice  Academic Article
• Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct jak kinase signaling pathways  Academic Article
• Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells  Academic Article
• Cytokine-mediated survival from lethal herpes-simplex virus-infection - role of programmed neuronal death  Academic Article
• Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures  Academic Article
• Cytokines regulate microglial adhesion to laminin and astrocyte extracellular matrix via protein kinase c-dependent activation of the alpha 6 beta 1 integrin  Academic Article
• Cytokines suppress apoptosis independent of increases in reactive oxygen levels  Academic Article
• Cytolytic T-lymphocyte response to isolated class I H-2 proteins and influenza peptides  Academic Article
• Cytomegalovirus causes a latent infection in undifferentiated cells and is activated by induction of cell-differentiation  Academic Article
• Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers  Academic Article
• Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes  Academic Article
• Cytoprotective-selective activated protein C attenuates pseudomonas aeruginosa-induced lung injury in mice  Academic Article
• Cytoprotective-selective activated protein C therapy for ischaemic stroke  Academic Article
• Cytoskeletal and morphologic impact of cellular oxidant injury  Academic Article
• Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies  Academic Article
• Cytosolic prion protein in neurons  Academic Article
• Cytotactin and its proteoglycan ligand mark structural and functional boundaries in somatosensory cortex of the early postnatal mouse  Academic Article
• Cytotactin binding - inhibition of stimulated proliferation and intracellular alkalinization in fibroblasts  Academic Article
• Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: interferon gamma, but not tumour necrosis factor alpha, displays antiviral activity in vivo  Academic Article
• Cytotoxic T-lymphocytes cleanse viral gene-products from individually infected neurons and lymphocytes in mice persistently infected with lymphocytic choriomeningitis virus  Academic Article
• Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice  Academic Article
• Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-jun n-terminal kinase  Academic Article
• D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain  Academic Article
• DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses  Academic Article
• DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis  Academic Article
• DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kruppel-like factor 15 gene expression  Academic Article
• DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization  Academic Article
• DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3  Academic Article
• DNA damage triggers a chronic autoinflammatory response, leading to fat depletion in NER progeria  Academic Article
• DNA immunization  Academic Article
• DNA immunization can stimulate florid local inflammation, and the antiviral immunity induced varies depending on injection site  Academic Article
• DNA immunization confers protection against lethal lymphocytic choriomeningitis virus-infection  Academic Article
• DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice  Academic Article
• DNA immunization to prevent autoimmune diabetes  Academic Article
• DNA immunization with minigenes: Low frequency of memory cytotoxic t lymphocytes and inefficient antiviral protection are rectified by ubiquitination  Academic Article
• DNA immunization: Effects of vehicle and route of administration on the induction of protective antiviral immunity  Academic Article
• DNA immunization: Ubiquitination of a viral protein enhances cytotoxic t-lymphocyte induction and antiviral protection but abrogates antibody induction  Academic Article
• DNA methylation and chromatin structure regulate T cell perforin gene expression  Academic Article
• DNA vaccination against vegf receptor 2 reduces atherosclerosis in ldl receptor-deficient mice  Academic Article
• DNA vaccination can break immunological tolerance to prp in wild-type mice and attenuates prion disease after intracerebral challenge  Academic Article
• DNA vaccination to treat autoimmune diabetes  Academic Article
• DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes  Academic Article
• DNA vaccines designed to inhibit tumor growth by suppression of angiogenesis  Academic Article
• DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis  Academic Article
• DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: Implications for eqtl mapping studies  Academic Article
• DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
• DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer  Academic Article
• DNA-sequences preceding the rabbit beta-globin gene are required for formation in mouse l cells of beta-globin rna with the correct 5' terminus  Academic Article
• DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis  Academic Article
• DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect  Academic Article
• DST4 - a new, and probably the last, functional DH gene in the BALB/c mouse  Academic Article
• Dab1 is required for synaptic plasticity and associative learning  Academic Article
• Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation  Academic Article
• Darwinian evolution of prions in cell culture  Academic Article
• Data-driven synthesis of proteolysis-resistant peptide hormones  Academic Article
• De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis  Academic Article
• Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function  Academic Article
• Decay-accelerating factor 1 (daf1) deficiency exacerbates xenobiotic-induced autoimmunity  Academic Article
• Deconstructing transcriptional heterogeneity in pluripotent stem cells  Academic Article
• Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo  Academic Article
• Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase  Academic Article
• Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system  Academic Article
• Decreased brain reward function during nicotine withdrawal in c57bl6 mice: Evidence from intracranial self-stimulation (icss) studies  Academic Article
• Decreased immobility in swimming test by homologous interferon-alpha in mice accompanied with increased cerebral tryptophan level and serotonin turnover  Academic Article
• Decreased phospho-Akt signaling in a mouse model of total parenteral nutrition: a potential mechanism for the development of intestinal mucosal atrophy  Academic Article
• Dedifferentiation of lineage-committed cells by a small molecule  Academic Article
• Deep proteome mapping of mouse kidney based on OFFGel prefractionation reveals remarkable protein post- translational modifications  Academic Article
• Deep sequencing of the murine Igh repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies  Academic Article
• Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation  Academic Article
• Deep-brain magnetic stimulation promotes adult hippocampal neurogenesis and alleviates stress-related behaviors in mouse models for neuropsychiatric disorders  Academic Article
• Defective CD8+ T cell peripheral tolerance in nonobese diabetic mice  Academic Article
• Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene  Academic Article
• Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice  Academic Article
• Defective lymphotoxin-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice  Academic Article
• Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function  Academic Article
• Defects in deletional tolerance of CD8+ T cells in autoimmune diabetes  Academic Article
• Defects in skin γδ T cell function contribute to delayed wound repair in rapamycin-treated mice  Academic Article
• Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist  Academic Article
• Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy  Academic Article
• Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances  Academic Article
• Deficiency of DNA repair nuclease ERCC1-XPF promotes prostate cancer progression in a tissue recombination model  Academic Article
• Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis  Academic Article
• Deficiency of lrp8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis  Academic Article
• Deficiency of the cyclin kinase inhibitor P21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoirnmunity  Academic Article
• Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the pkr gene: Role of irf-1 and nf-kappa b  Academic Article
• Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity  Academic Article
• Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase  Academic Article
• Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice  Academic Article
• Defined and scalable differentiation of human oligodendrocyte precursors from pluripotent stem cells in a 3D culture system  Academic Article
• Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns  Academic Article
• Defining parameters for successful immunocytotherapy of persistent viral infection  Academic Article
• Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro  Academic Article
• Defining the conformational features of anchorless, poorly neuroinvasive prions  Academic Article
• Defining the critical hypoxic threshold that promotes vascular remodeling in the brain  Academic Article
• Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndrome  Academic Article
• Defining the risks of mesenchymal stromal cell therapy  Academic Article
• Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity  Academic Article
• Degradation, foraging, and depletion of mucus sialoglycans by the vagina-adapted Actinobacterium Gardnerella vaginalis  Academic Article
• Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis  Academic Article
• Delayed and accelerated aging share common longevity assurance mechanisms  Academic Article
• Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors  Academic Article
• Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice  Academic Article
• Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization  Academic Article
• Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival  Academic Article
• Deletion of PREPl causes growth impairment and hypotonia in mice  Academic Article
• Deletion of ghrelin impairs neither growth nor appetite  Academic Article
• Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus  Academic Article
• Deletion of naive CD8 T cells requires persistent antigen and is not programmed by an initial signal from the tolerogenic APC  Academic Article
• Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice  Academic Article
• Deletion of p21 (WAF-1/Cip1) does not induce systemic autoimmunity in female BXSB mice  Academic Article
• Deletion of the nucleotide excision repair gene ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions  Academic Article
• Deletions linked to TP53 loss drive cancer through p53-independent mechanisms  Academic Article
• Deletions within the 5 ' utr of coxsackievirus b3: Consequences for virus translation and replication  Academic Article
• Deliberate removal of T cell help improves virus-neutralizing antibody production  Academic Article
• Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects  Academic Article
• Delineation of a defect in t-cell receptor beta-genes of nzw mice predisposed to autoimmunity  Academic Article
• Delineation of spontaneous erythrocyte autoantibody responses of nzb and other strains of mice  Academic Article
• Delineation of the proinflammatory cytokine cascade in fever induction  Academic Article
• Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes  Academic Article
• Delta(9)-tetrahydrocannabinol immunochemical studies: Haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta(9)-tetrahydrocannabinol  Academic Article
• Delta-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects  Academic Article
• Demonstration of a hematopoietic stem-cell antigen (SC-1) on a murine lymphoma and isolation of variants lacking the antigen  Academic Article
• Demonstration of dehydrogenases and monoamine-oxidase by formation of osmium blacks at sites of hatchetts brown  Academic Article
• Demonstration of developmental anomalies in mouse fetuses by transfer of murine cytomegalovirus DNA-injected eggs to surrogate mothers  Academic Article
• Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation  Academic Article
• Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation  Academic Article
• Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice  Academic Article
• Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity  Academic Article
• Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection  Academic Article
• Dendritic cells produce macrophage inflammatory protein-1 gamma, a new member of the CC chemokine family  Academic Article
• Dendritic cells transduced to express interleukin 4 reduce diabetes onset in both normoglycemic and prediabetic nonobese diabetic mice  Academic Article
• Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis  Academic Article
• Dendritic epidermal T cells regulate skin antimicrobial barrier function  Academic Article
• Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1  Academic Article
• Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin  Academic Article
• Dense nuclear cataract caused by the γB-crystallin S11R point mutation  Academic Article
• Density-dependent stimulation and inhibition of cell-growth by agents that disrupt microtubules  Academic Article
• Dentate gyrus volume is reduced before onset of plaque formation in pdapp mice: A magnetic resonance microscopy and stereologic analysis  Academic Article
• Dentin conditioning codetermines cell fate in regenerative endodontics  Academic Article
• Dependence-induced increases in ethanol self-administration in mice are blocked by the crf, receptor antagonist antalarmin and by crf, receptor knockout  Academic Article
• Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation  Academic Article
• Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors  Academic Article
• Depletion of complement does not impact initiation of xenobiotic-induced autoimmune disease  Academic Article
• Depletion of fat-resident T-reg cells prevents age-associated insulin resistance  Academic Article
• Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes  Academic Article
• Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions   Academic Article
• Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland  Academic Article
• Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway  Academic Article
• Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland  Academic Article
• Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes  Academic Article
• Derivation of microglia-free astrocyte cultures from neural stem cells  Academic Article
• Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse-transcriptase and suppress human and feline immunodeficiency virus expression in cultured-cells  Academic Article
• Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease  Academic Article
• Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor  Academic Article
• Design and discovery of N-(2-Methyl-5 '-morpholino-6 '-((tetrahydro-2H-pyran-4-yl)oxy)- 3,3 '-bipyridin -5-yl)-3-(trifluoromethyl)benzamide (RAF709): a potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers  Academic Article
• Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300  Academic Article
• Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives  Academic Article
• Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors  Academic Article
• Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase  Academic Article
• Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant  Academic Article
• Design of high-affinity major histocompatibility complex-specific antagonist peptides that inhibit cytotoxic lymphocyte-t activity - implications for control of viral disease  Academic Article
• Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d  Academic Article
• Design of polydactyl zinc-finger proteins for unique addressing within complex genomes  Academic Article
• Design of potent and proteolytically stable oxyntomodulin analogs  Academic Article
• Design of potent and selective 2-aminobenzimidazole-based p38 alpha MAP kinase inhibitors with excellent in vivo efficacy  Academic Article
• Design, synthesis and SAR of novel glucokinase activators  Academic Article
• Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold  Academic Article
• Design, synthesis and evaluation of bouvardin, deoxybouvardin and RA-I-XIV pharmacophore analogs  Academic Article
• Design, synthesis, and characterization of alpha-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase  Academic Article
• Design, synthesis, and evaluation of duocarmycin O-amino phenol prodrugs subject to tunable reductive activation  Academic Article
• Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors  Academic Article
• Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists  Academic Article
• Designing 3-D adipospheres for quantitative metabolic study  Academic Article
• Designing arenaviral vaccines  Academic Article
• Designing small-molecule switches for protein-protein interactions  Academic Article
• Detailed in vivo analysis of interferon-gamma induced major histocompatibility complex expression in the central nervous system: Astrocytes fail to express major histocompatibility complex class i and ii molecules  Academic Article
• Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis  Academic Article
• Detecting expression of 5T4 in CTCs and tumor samples from NSCLC patients  Academic Article
• Detecting genetic variation in microarray expression data  Academic Article
• Detection and partial characterization of circulating immune-complexes with solid-phase anti-c3  Academic Article
• Detection of a recombinant murine leukemia virus-related glycoprotein on virus-negative thymoma cells  Academic Article
• Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging  Academic Article
• Detection of h-2 antigens in serum  Academic Article
• Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing  Academic Article
• Detection of low-avidity CD4(+) T cells using recombinant artificial APC: following the antiovalbumin immune response  Academic Article
• Detection of malignant melanoma with monoclonal antibodies  Academic Article
• Detection of naturally occurring antibodies to rna-dependent DNA-polymerase of murine leukemia-virus in kidney eluates of akr mice  Academic Article
• Detection of prion infectivity in fat tissues of scrapie-infected mice  Academic Article
• Detection of transforming oncogenes in rat colon tumors induced by direct perfusion with N-methyl-N-nitrosourea  Academic Article
• Detection of vitronectin mRNA in tissues and cells of the mouse  Academic Article
• Detection, identification, and partial characterization of serine proteases and esterases in biological-systems  Academic Article
• Determinants of P3 amplitude and response to alcohol in Native American Mission Indians  Academic Article
• Determination of key aspects of precursor cell proliferation, cell cycle length and kinetics in the adult mouse subgranular zone  Academic Article
• Development and maintenance of a b220(-) memory b cell compartment  Academic Article
• Development and mechanism of γ-secretase modulators for Alzheimer's disease  Academic Article
• Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15  Academic Article
• Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-beta-Hexosaminidase Inhibitors  Academic Article
• Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection  Academic Article
• Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models  Academic Article
• Development of all CD4 T lineages requires nuclear factor TOX  Academic Article
• Development of an affinity chromatography resin for the purification of carcinogen binding proteins from mouse liver  Academic Article
• Development of anti-CD74 antibody-drug conjugates to target glucocorticoids to immune cells  Academic Article
• Development of antigen-specific helper T cell responses in vivo: antigen-specific Th cell subsets  Academic Article
• Development of approaches to improve cell survival in myoblast transfer therapy  Academic Article
• Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens  Academic Article
• Development of chemical probes for investigation of salt-inducible kinase function in vivo  Academic Article
• Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris  Academic Article
• Development of ecdysone-regulated lentiviral vectors  Academic Article
• Development of functionally selective, small molecule agonists at kappa opioid receptors  Academic Article
• Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties  Academic Article
• Development of immature thymocytes - initiation of CD3, CD4, and CD8 acquisition parallels down-regulation of the interleukin-2 receptor alpha-chain  Academic Article
• Development of insulin resistance in mice lacking PGC-1α in adipose tissues  Academic Article
• Development of live-attenuated arenavirus vaccines based on codon deoptimization  Academic Article
• Development of lupus in BXSB mice is independent of IL-4  Academic Article
• Development of oseltamivir phosphonate congeners as anti-influenza agents  Academic Article
• Development of pegylated forms of recombinant rhodosporidium toruloides phenylalanine ammonia-lyase for the treatment of classical phenylketonuria  Academic Article
• Development of proneurogenic, neuroprotective small molecules  Academic Article
• Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p  Academic Article
• Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain  Academic Article
• Developmental biology: The early heart remodelled  Academic Article
• Developmental control of n-cam expression by hox and pax gene-products  Academic Article
• Developmental expression of sorting nexin 3 in the mouse central nervous system  Academic Article
• Developmental expression of the alpha(iel)beta(7) integrin on t-cell receptor-gamma-delta and t-cell receptor-alpha-beta t-cells  Academic Article
• Developmental neurobiology: A genetic cheshire cat?  Academic Article
• Developmental regulation of TREM2 and DAP12 expression in the murine CNS: implications for Nasu-Hakola disease  Academic Article
• Developmental regulation of Zbu1, a DNA-binding member of the SWI2/SNF2 family  Academic Article
• Developmental regulation of b lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection  Academic Article
• Developmental regulation of beta 1 integrins during angiogenesis in the central nervous system  Academic Article
• Developmentally distinct th cells control plasma cell production in vivo  Academic Article
• Developmentally ordered appearance of thymocytes expressing different t-cell antigen receptors  Academic Article
• Developmentally regulated use of alternative promoters creates a novel platelet-derived growth-factor receptor transcript in mouse teratocarcinoma and embryonic stem-cells  Academic Article
• Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin tumor-necrosis-factor synthesis at separate points in the signaling pathway  Academic Article
• Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands  Academic Article
• Dhhc5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells  Academic Article
• Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1  Academic Article
• Diabetes insipidus in mice with a mutation in aquaporin-2  Academic Article
• Diced electrophoresis gel assay for screening enzymes with specified activities  Academic Article
• Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice  Academic Article
• Diet and feeding pattern affect the diurnal dynamics of the gut microbiome  Academic Article
• Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or-4 receptors  Academic Article
• Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics  Academic Article
• Differences in experimental tumor-localization of dual-labeled monoclonal-antibody  Academic Article
• Differences in one-way active-avoidance learning in mice of 3 inbred strains  Academic Article
• Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive cd4(+) t-cells by anti-cd4 monoclonal-antibody (gk1.5) in young and aged mice  Academic Article
• Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice  Academic Article
• Differences in the liability to self-administer intravenous cocaine between c57bl/6xsjl and balb/cbyj mice  Academic Article
• Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP  Academic Article
• Different mechanisms of increased luminal stenosis after arterial injury in mice deficient for urokinase- or tissue-type plasminogen activator  Academic Article
• Different pathways mediate virus inducibility of the human ifn-alpha-1 and ifn-beta genes  Academic Article
• Different regulatory elements are required for response of hepcidin to interleukin-6 and bone morphogenetic proteins 4 and 9  Academic Article
• Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes  Academic Article
• Differential T cell responses to residual viral antigen prolong CD4(+) T cell contraction following the resolution of infection  Academic Article
• Differential antitumor effects of administration of recombinant IL-18 or recombinant IL-12 are mediated primarily by Fas-Fas ligand- and perforin-induced tumor apoptosis, respectively  Academic Article
• Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation  Academic Article
• Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen  Academic Article
• Differential effects of a new amphotericin B derivative, MS-8209, on mouse BSE and scrapie: Implications for the mechanism of action of polyene antibiotics  Academic Article
• Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice  Academic Article
• Differential effects of il-12 on the generation of alloreactive ctl mediated by murine and human dendritic cells: A critical role for nitric oxide  Academic Article
• Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice  Academic Article
• Differential effects of morphine, dpdpe, and u-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice  Academic Article
• Differential effects of morphine- and cocaine-induced nnos immunoreactivity in the dentate gyrus of hippocampus of mice lacking mu-opioid receptors  Academic Article
• Differential effects of n-peptidyl-o-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test  Academic Article
• Differential effects of pharmacologic and genetic modulation of NMDA receptor activity on HIV/gp120-induced neuronal damage in an in vivo mouse model  Academic Article
• Differential expression of 2 distinct xenotropic viruses in nzb mice  Academic Article
• Differential expression of the repertoire in in vitro and in vivo responses to minor alloantigens  Academic Article
• Differential gene expression in lps/ifn gamma activated microglia and macrophages: In vitro versus in vivo  Academic Article
• Differential gene expression in the developing lateral geniculate nucleus and medial geniculate nucleus reveals novel roles for Zic4 and Foxp2 in visual and auditory pathway development  Academic Article
• Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis  Academic Article
• Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis  Academic Article
• Differential internalization of hu14.18-il2 immunocytokine by nk and tumor cell: Impact on conjugation, cytotoxicity, and targeting  Academic Article
• Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy  Academic Article
• Differential mechanisms of morphine antinociceptive tolerance revealed in beta arrestin-2 knock-out mice  Academic Article
• Differential modulation by the stress axis of ethanol withdrawal seizure expression in WSP and WSR mice  Academic Article
• Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation  Academic Article
• Differential protective effects of connective tissue growth factor against Aβ neurotoxicity on neurons and glia.  Academic Article
• Differential regulation by multiple promoters of the gene encoding the neuron-restrictive silencer factor  Academic Article
• Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites  Academic Article
• Differential regulation of E2F and Sp1-mediated transcription by G1 cyclins  Academic Article
• Differential regulation of antiviral T-cell immunity results in stable CD8(+) but declining CD4(+) T-cell memory  Academic Article
• Differential regulation of beta-1-adrenergic and beta-2-adrenergic receptor protein and messenger-rna levels by glucocorticoids during 3t3-f442a adipose differentiation  Academic Article
• Differential regulation of cell motility and invasion by fak  Academic Article
• Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation  Academic Article
• Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone  Academic Article
• Differential regulation of vitronectin in mice and humans in vitro  Academic Article
• Differential role of melanocortin receptor subtypes in cachexia  Academic Article
• Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry  Academic Article
• Differential target cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice  Academic Article
• Differential utilization of upstream augs in the beta-secretase mrna suggests that a shunting mechanism regulates translation  Academic Article
• Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in g86r superoxide dismutase transgenic mice  Academic Article
• Differential-effects of cytotactin tenascin fusion proteins on intracellular ph and cell morphology  Academic Article
• Differential-effects of the cytoplasmic domains of cell-adhesion molecules on cell-aggregation and sorting-out  Academic Article
• Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice  Academic Article
• Differentiation of Mycoplasma mycoides subsp. mycoides from certain closely related caprine mycoplasmas by mycoplasmaemia and cross-protection tests in mice  Academic Article
• Differentiation of mouse keratinocytes is accompanied by pkc-dependent changes in ap-1 proteins  Academic Article
• Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTen-dependent mechanism  Academic Article
• Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors  Academic Article
• Diphosphoryl lipid-a from rhodopseudomonas-sphaeroides atcc 17023 blocks induction of cachectin in macrophages by lipopolysaccharide  Academic Article
• Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects  Academic Article
• Direct comparison of Dll1-and Dll4-mediated notch activation levels shows differential lymphomyeloid lineage commitment outcomes  Academic Article
• Direct ex vivo kinetic and phenotypic analyses of cd8(+) t-cell responses induced by DNA immunization  Academic Article
• Direct imaging of interactions between an icosahedral virus and conjugate f-ab fragments by cryoelectron microscopy and x-ray crystallography  Academic Article
• Direct immunofluorescent tissue culture assay for lymphocytic choriomeningitis virus  Academic Article
• Direct induction of cyclin d2 by myc contributes to cell cycle progression and sequestration of p27  Academic Article
• Direct interferon-gamma signalling and cd8(+) t cell memory  Academic Article
• Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe  Academic Article
• Direct regulation of clock expression by rev-erb  Academic Article
• Direct reprogramming of mouse fibroblasts to neural progenitors  Academic Article
• Direct targeting of αvβ3 integrin on tumor cells with a monoclonal antibody, Abegrin™  Academic Article
• Directed enzyme evolution guided by multidimensional analysis of substrate-activity space  Academic Article
• Discovering disease-associated enzymes by proteome reactivity profiling  Academic Article
• Discovering potent and selective reversible inhibitors of enzymes in complex proteomes  Academic Article
• Discovery and characterization of a mammalian amyloid disaggregation activity  Academic Article
• Discovery and characterization of an endogenous CXCR4 antagonist  Academic Article
• Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2  Academic Article
• Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)  Academic Article
• Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability  Academic Article
• Discovery metabolite profiling - forging functional connections between the proteome and metabolome  Academic Article
• Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer  Academic Article
• Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer  Academic Article
• Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia  Academic Article
• Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors  Academic Article
• Discovery of 3-cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo 2,3-b pyridin-5-yObenzamide: a potent, selective, and orally bioavailable retinoic acid receptor related orphan receptor C2 inverse agonist  Academic Article
• Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia  Academic Article
• Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system  Academic Article
• Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer  Academic Article
• Discovery of GlyT1 inhibitors with improved pharmacokinetic properties  Academic Article
• Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia  Academic Article
• Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-m ethyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through structure-based drug design: a high affinity irreversible inhibitor targeting oncogenic EGFR mutants with selectivity over wild-type EGFR  Academic Article
• Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition  Academic Article
• Discovery of a noncovalent, mutant-selective epidermal growth factor receptor inhibitor  Academic Article
• Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomain of CBP/EP300  Academic Article
• Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer  Academic Article
• Discovery of a proneurogenic, neuroprotective chemical  Academic Article
• Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design  Academic Article
• Discovery of a small molecule insulin mimetic with antidiabetic activity in mice  Academic Article
• Discovery of a small-molecule BMP sensitizer for human embryonic stem cell differentiation  Academic Article
• Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors  Academic Article
• Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements  Academic Article
• Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors  Academic Article
• Discovery of matrix metalloproteases selective and activated peptide-doxorubicin prodrugs as anti-tumor agents  Academic Article
• Discovery of native autoantigens via antigen surrogate technology: Application to type 1 diabetes  Academic Article
• Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design  Academic Article
• Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients  Academic Article
• Discovery of potent and bioavailable GSK-3β inhibitors  Academic Article
• Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors  Academic Article
• Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties  Academic Article
• Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators  Academic Article
• Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model  Academic Article
• Discovery of pyrrolo 1,2-b pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors  Academic Article
• Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na(v)1.7 inhibitors with pain efficacy in mice  Academic Article
• Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2)  Academic Article
• Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist  Academic Article
• Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (s1p(4)-r) agonists  Academic Article
• Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)  Academic Article
• Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3  Academic Article
• Discrete BDNF neurons in the paraventricular hypothalamus control feeding and energy expenditure  Academic Article
• Discriminated selection among viral peptides with the appropriate anchor residues - implications for the size of the cytotoxic t-lymphocyte repertoire and control of viral-infection  Academic Article
• Disease accompanying in utero viral infection. The role of maternal antibody in tissue injury after transplacental infection with lymphocytic choriomeningitis virus  Academic Article
• Disease model: Dissecting the pathogenesis of the measles virus  Academic Article
• Disease modifying potential of glatiramer acetate in Huntington's disease  Academic Article
• Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders  Academic Article
• Disialoganglioside gd3 on human-melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis  Academic Article
• Disproportionate inhibition of feeding in a(y) mice by certain stressors: A cautionary note  Academic Article
• Disproportionate recruitment of cd8(+) t cells into the central nervous system by professional antigen-presenting cells  Academic Article
• Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity  Academic Article
• Disruption of Gja8 (α8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation  Academic Article
• Disruption of angiogenesis by pex, a noncatalytic metalloproteinase fragment with integrin binding activity  Academic Article
• Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease  Academic Article
• Disruption of dendritic translation of camkii alpha impairs stabilization of synaptic plasticity and memory consolidation  Academic Article
• Disruption of differentiated functions during viral infection in vivo - v. Mapping of a locus involved in susceptibility of mice to growth hormone deficiency due to persistent lymphocytic choriomeningitis virus infection  Academic Article
• Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure  Academic Article
• Disruption of myd88 signaling suppresses hemophagocytic lymphohistiocytosis in mice  Academic Article
• Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal  Academic Article
• Disruption of the arf transcriptional activator dmp1 facilitates cell immortalization, ras transformation, and tumorigenesis  Academic Article
• Disruption of the arf-mdm2-p53 tumor suppressor pathway in myc-induced lymphomagenesis  Academic Article
• Disruption of the chaperonin containing TCP-1 function affects protein networks essential for rod outer segment morphogenesis and survival  Academic Article
• Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome  Academic Article
• Disruption of the plasminogen activator inhibitor-1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice  Academic Article
• Disruption of tissue-specific fucosyltransferase vii, an enzyme necessary for selectin ligand synthesis, suppresses atherosclerosis in mice  Academic Article
• Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice  Academic Article
• Dissecting influenza virus pathogenesis uncovers a novel chemical approach to combat the infection  Academic Article
• Dissecting the molecular anatomy of persistent infection with lymphocytic choriomeningitis virus  Academic Article
• Dissecting the molecular anatomy of the nervous system: analysis of RNA and protein expression in whole body sections of laboratory animals  Academic Article
• Dissecting the requirements for maintenance of the cmv-specific memory t-cell pool  Academic Article
• Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire  Academic Article
• Dissection of the BCL-2 family signaling network with stabilized alpha-helices of BCL-2 domains  Academic Article
• Dissection of the insulin-sensitizing effect of liver x receptor ligands  Academic Article
• Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice  Academic Article
• Dissociation of locomotor activation and suppression of food intake induced by crf in crfr1-deficient mice  Academic Article
• Dissociation of the effect of aminoglutethimide on corticosterone biosynthesis from ataxic and hypothermic effects in DBA and C57 mice  Academic Article
• Dissociation of the opioid receptor mechanisms that control mechanical and heat pain  Academic Article
• Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)  Academic Article
• Distinct APCs explain the cytokine bias of alpha-galactosylceramide variants in vivo  Academic Article
• Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region  Academic Article
• Distinct TCR signaling pathways drive proliferation and cytokine production in T cells  Academic Article
• Distinct and opposing roles for Rab27a/MIph/MyoVa and Rab27b/Munc13-4 in mast cell secretion  Academic Article
• Distinct antithrombotic consequences of platelet glycoprotein Ibα and VI deficiency in a mouse model of arterial thrombosis  Academic Article
• Distinct conformational spectrum of homologous multidrug ABC transporters  Academic Article
• Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III  Academic Article
• Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease  Academic Article
• Distinct endocytic mechanisms of cd22 (siglec-2) and siglec-f reflect roles in cell signaling and innate immunity  Academic Article
• Distinct footprints of tcr engagement with highly homologous ligands  Academic Article
• Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus  Academic Article
• Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure  Academic Article
• Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors  Academic Article
• Distinct rate and patterns of human CD4+ T-cell depletion in hu-PBL-SCID mice infected with different isolates of the human immunodeficiency virus  Academic Article
• Distinct requirements for deletion versus anergy during CD8 T cell peripheral tolerance in vivo  Academic Article
• Distinct role of long 3 ' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons  Academic Article
• Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci  Academic Article
• Distinct roles for astrocyte alpha v beta 5 and alpha v beta 8 integrins in adhesion and migration  Academic Article
• Distinct roles for somatically and dendritically synthesized brain-derived neurotrophic factor in morphogenesis of dendritic spines  Academic Article
• Distinct roles of cytoskeletal components in immunological synapse formation and directed secretion  Academic Article
• Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapse  Academic Article
• Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature b cells  Academic Article
• Distinct spatio-temporal Ca(2+) signaling elicited by integrin alpha 2 beta 1 and glycoprotein VI under flow  Academic Article
• Distinction between malignant l cells and normal mouse fibroblasts by rosette formation with sheep red blood-cells  Academic Article
• Distinctions in beta-adrenergic-receptor interactions with the magnesium-guanine nucleotide coupling proteins in turkey erythrocyte and s49-lymphoma membranes  Academic Article
• Distortion of cell functions by noncytotoxic viruses  Academic Article
• Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide  Academic Article
• Distribution of endotoxin (lipopolysaccharide) in tissues of lipopolysaccharide-responsive and lipopolysaccharide-unresponsive mice  Academic Article
• Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes  Academic Article
• Distribution of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected trigeminal ganglia in the mouse  Academic Article
• Distribution of vitronectin mRNA during murine development  Academic Article
• Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists  Academic Article
• Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors  Academic Article
• Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor  Academic Article
• Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα  Academic Article
• Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis  Academic Article
• Diverse roles of Eph/ephrin signaling in the mouse lens  Academic Article
• Diversity of T-cell receptors in virus-specific cytotoxic T lymphocytes recognizing three distinct viral epitopes restricted by a single major histocompatibility complex molecule  Academic Article
• Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis  Academic Article
• Division of labor of schwann cell integrins during migration on peripheral nerve extracellular matrix ligands  Academic Article
• Do t cells need endogenous peptides for activation?  Academic Article
• Does preferential Th subset activation contribute to the murine acquired immunodeficiency disease (MAIDS)?  Academic Article
• Does the major histocompatibility complex serve as a specific receptor for semliki forest virus  Academic Article
• Does toll-like receptor 3 play a biological role in virus infections?  Academic Article
• Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor  Academic Article
• Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3  Academic Article
• Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation  Academic Article
• Dominant cataracts result from incongruous mixing of wild-type lens connexins  Academic Article
• Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis  Academic Article
• Dopamine d1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral-responses  Academic Article
• Dopamine neurotransmission is involved in the attenuating effects of 5-ht3 receptor antagonist mdl 72222 on acute methamphetamine-induced locomotor hyperactivity in mice  Academic Article
• Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons  Academic Article
• Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice  Academic Article
• Dorsal raphe dopamine neurons modulate arousal and promote wakefulness by salient stimuli  Academic Article
• Dose response and timing effects in the therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate  Academic Article
• Dose- and time-dependent bimodal effects of kappa-opioid agonists on locomotor activity in mice  Academic Article
• Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake  Academic Article
• Double-strand DNA breaks recruit the centromeric histone CENP-A  Academic Article
• Double-stranded rna-mediated tlr3 activation is enhanced by cd14  Academic Article
• Down-regulation of MHC class-I antigen in insulinoma cells controlled by the R1 element of the H-2 enhancer  Academic Article
• Down-regulation of beta(3) adrenoreceptor gene expression in brown fat cells is transient and recovery is dependent upon a short-lived protein factor  Academic Article
• Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice  Academic Article
• Down-regulation of the major histocompatibility complex class-I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding  Academic Article
• Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin  Academic Article
• Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient mice  Academic Article
• Downregulation of transcription factor sox2 in cancer stem cells suppresses growth and metastasis of lung cancer  Academic Article
• Downregulation of tumor growth and invasion by redox-active nanoparticles  Academic Article
• Doxorubicin conjugated with a monoclonal-antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude-mice  Academic Article
• Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies  Academic Article
• Drug target validation: lethal infection blocked by inducible peptide  Academic Article
• Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition  Academic Article
• DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetes  Academic Article
• DsAAV8-mediated gene transfer and beta-cell expression of IL-4 and beta-cell growth factors are capable of reversing early-onset diabetes in NOD mice  Academic Article
• Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression  Academic Article
• Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo  Academic Article
• Dual control of myc expression through a single DNA-binding site targeted by ets family proteins and e2f-1  Academic Article
• Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like morris water maze deficits in mice  Academic Article
• Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice  Academic Article
• Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: Actin depolymerization by Ca2+-alpha-actinin and polymerization by rho  Academic Article
• Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification  Academic Article
• Dueling activities of AIF in cell death versus survival: DNA binding and redox activity  Academic Article
• Dynamic actin filaments are required for stable long-term potentiation (ltp) in area ca1 of the hippocampus  Academic Article
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• Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4  Academic Article
• Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express il-4  Academic Article
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• Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice  Academic Article
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• Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse  Academic Article
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• Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch  Academic Article
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• Effects of environmental enrichment on gene expression in the brain  Academic Article
• Effects of ginseng total saponin on cocaine-induced hyperactivity and conditioned place preference in mice  Academic Article
• Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice  Academic Article
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• Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase  Academic Article
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• Effects of morphine on pentobarbital-induced responses in mu-opioid receptor knockout mice  Academic Article
• Effects of naltrexone and acamprosate on alcohol-induced ngfi-a expression in mouse brain  Academic Article
• Effects of sodium metaperiodate on t and b lymphocytes  Academic Article
• Effects of soluble TNF receptor treatment on lipopolysaccharide-induced myocardial cytokine expression  Academic Article
• Effects of the endogenous PPAR-alpha agonist, oleoylethanolamide on MDMA-induced cognitive deficits in mice  Academic Article
• Effects of the ginsenosides rg(1) and rb-1 on morphine-induced hyperactivity and reinforcement in mice  Academic Article
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• Effects of the specific alpha 4 beta 2 nachr antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice  Academic Article
• Effects of topical Janus kinase inhibition on ocular surface inflammation and immunity  Academic Article
• Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs  Academic Article
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• Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice  Academic Article
• Efficiency and effectiveness of cloned virus-specific cytotoxic T lymphocytes in vivo  Academic Article
• Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes  Academic Article
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• Efficient peripheral clonal elimination of b lymphocytes in mrl/lpr mice bearing autoantibody transgenes  Academic Article
• Efficient preparation of site-specific antibody-drug conjugates using cysteine insertion  Academic Article
• Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2  Academic Article
• Efficient t cell activation via a toll-interleukin 1 receptor-independent pathway  Academic Article
• Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone-marrow transduced by a retroviral vector  Academic Article
• Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells  Academic Article
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• Electrical remodeling of preoptic GABAergic neurons involves the Kv1.5 subunit  Academic Article
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• Electron microscopic localization of corticotropin-releasing factor (CRF) and CRF receptor in rat and mouse central nucleus of the amygdala  Academic Article
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• Enhancement of fgf-like polypeptides in the retinae of newborn mice exposed to hyperoxia  Academic Article
• Enhancement of infectivity and oncogenicity of a murine leukemia-virus in adult mice by x-irradiation  Academic Article
• Enhancement of metastasis development by bcg immunotherapy  Academic Article
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• Enterotoxin residues determining t-cell receptor v-beta binding-specificity  Academic Article
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• Envelope exchange for the generation of live-attenuated arenavirus vaccines  Academic Article
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• EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens  Academic Article
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• Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation  Academic Article
• Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories  Academic Article
• Epigenetic regulation of pluripotency and differentiation  Academic Article
• Epithelial membrane protein-1 is a biomarker of gefitinib resistance  Academic Article
• Epithelial p38 alpha controls immune cell recruitment in the colonic mucosa  Academic Article
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• Epstein-Barr-virus complement C3d receptor is an interferon-alpha receptor  Academic Article
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• Eradication of human hepatic and pulmonary melanoma metastases in scid mice by antibody-interleukin 2 fusion proteins  Academic Article
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• Ercc1/xpf removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes  Academic Article
• Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders  Academic Article
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• Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus  Academic Article
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• Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription  Academic Article
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• Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors  Academic Article
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• Evaluation of protective immunity to HIV-1 in human PBL-SCID mice  Academic Article
• Evaluation of quinacrine treatment for prion diseases  Academic Article
• Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose  Academic Article
• Evaluation of the echinocandin antifungal mk-0991 (l-743,872): Efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis  Academic Article
• Evasion of the p53 tumour surveillance network by tumour-derived myc mutants  Academic Article
• Event-related oscillations as risk markers in genetic mouse models of high alcohol preference  Academic Article
• Event-related oscillations in mice: Effects of stimulus characteristics  Academic Article
• Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling  Academic Article
• Evidence for a b-lymphocyte defect underlying anti-x anti-erythrocyte autoantibody response of nzb-mice  Academic Article
• Evidence for an underlying cd4 helper and cd8 t-cell defect in b-cell-deficient mice: Failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from mu mt/mu mt mice  Academic Article
• Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation  Academic Article
• Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle  Academic Article
• Evidence for genetic association of RORB with bipolar disorder  Academic Article
• Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens  Academic Article
• Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer  Academic Article
• Evidence in locomotion test for the functional heterogeneity of orl-1 receptors  Academic Article
• Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice  Academic Article
• Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus  Academic Article
• Evidence that TRPC1 is involved in hippocampal glutamate-induced cell death  Academic Article
• Evidence that a single nucleotide polymorphism in the promoter of the g protein receptor kinase 3 gene is associated with bipolar disorder  Academic Article
• Evidence that extrahepatic cells express vitronectin mRNA at rates approaching those of hepatocytes  Academic Article
• Evidence that gene activation and silencing during stem cell differentiation requires a transcriptionally paused intermediate state  Academic Article
• Evidence that hi-terminal fragments of nociceptin modulate nociceptin-induced scratching, biting and licking in mice  Academic Article
• Evidence that tRNA synthetase-directed proton transfer stops mistranslation  Academic Article
• Evidence that the hypermutated m protein of a subacute sclerosing panencephalitis measles virus actively contributes to the chronic progressive cns disease  Academic Article
• Evolution of Cu Zn superoxide-dismutase and the Greek key beta-barrel structural motif  Academic Article
• Evolution of antigen-specific t cell receptors in vivo: Preimmune and antigen-driven selection of preferred complementarity-determining region 3 (cdr3) motifs  Academic Article
• Evolutionary conservation of key structures and binding functions of neural cell-adhesion molecules  Academic Article
• Evolutionary genetics: CCR5 mutation and plague protection  Academic Article
• Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS  Academic Article
• Ex vivo cytosolic delivery of functional macromolecules to immune cells  Academic Article
• Ex vivo gene delivery of il-1ra and soluble tnf receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis  Academic Article
• Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models  Academic Article
• Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation  Academic Article
• Exacerbation of murine listeriosis by a monoclonal-antibody specific for the type-3 complement receptor of myelomonocytic cells - absence of monocytes at infective foci allows listeria to multiply in nonphagocytic cells  Academic Article
• Exacerbation of viral and autoimmune animal models for multiple sclerosis by bacterial DNA  Academic Article
• Examining vascular remodeling in the hypoxic central nervous system  Academic Article
• Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits  Academic Article
• Exclusion of circulating t-cells from the thymus does not apply in the neonatal-period  Academic Article
• Exocytotic fusion is activated by rab3a peptides  Academic Article
• Exocytotic fusion pores are composed of both lipids and proteins  Academic Article
• Exogenous S1P exposure potentiates ischemic stroke damage that is reduced possibly by inhibiting S1P receptor signaling  Academic Article
• Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections  Academic Article
• Exogenous beta 2-microglobulin is required for antigenic peptide binding to isolated class I major histocompatibility complex molecules  Academic Article
• Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis  Academic Article
• Exosome-encapsulated antibiotic against intracellular infections of methicillin-resistant Staphylococcus aureus  Academic Article
• Exosomes as a short-range mechanism to spread alloantigen between dendiritic cells during T cell allorecognition  Academic Article
• Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis  Academic Article
• Exosomes derived from genetically modified dc expressing fasl are anti-inflammatory and immunosuppressive  Academic Article
• Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice  Academic Article
• Exosomes released from mycoplasma infected tumor cells activate inhibitory B cells  Academic Article
• Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network  Academic Article
• Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease  Academic Article
• Expanded potential for recombinant trisegmented lymphocytic choriomeningitis viruses: Protein production, antibody production, and in vivo assessment of biological function of genes of interest  Academic Article
• Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity  Academic Article
• Expanding the binding envelope of CYP51 inhibitors targeting Trypanosoma cruzi with 4-aminopyridyl-based sulfonamide derivatives  Academic Article
• Expanding the concept of chemically programmable antibodies to rna aptamers: Chemically programmed biotherapeutics  Academic Article
• Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform  Academic Article
• Expanding the scope of site-specific recombinases for genetic and metabolic engineering  Academic Article
• Expansion and function of CD8(+) T cells, expressing Ly49 inhibitory receptors specific for MHC class I molecules  Academic Article
• Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes  Academic Article
• Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen  Academic Article
• Experience-dependent remodeling of basket cell networks in the dentate gyrus  Academic Article
• Experimental characterization of electrostatic and conformational heterogeneity in an SH3 domain  Academic Article
• Experimental skin lesions in mice resembling systemic lupus erythematosus  Academic Article
• Explicit water near the catalytic I helix Thr in the predicted solution structure of CYP2A4  Academic Article
• Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor  Academic Article
• Exploring spatiotemporal organization of SCN circuits  Academic Article
• Exploring the energy landscape of antibody-antigen complexes: Protein dynamics, flexibility, and molecular recognition  Academic Article
• Exploring the scope of the 29g12 antibody catalyzed 1,3-dipolar cycloaddition reaction  Academic Article
• Export of protein from the endoplasmic-reticulum is regulated by a diacylglycerol phorbol ester binding-protein  Academic Article
• Exposure of plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity  Academic Article
• Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine d-1-like receptors in mice  Academic Article
• Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate  Academic Article
• Expression and characterization of a humanized cocaine-binding antibody  Academic Article
• Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: Roles in the adhesion and migration of putative endocrine progenitor cells  Academic Article
• Expression and function of the cd3-antigen receptor on murine cd4+8+ thymocytes  Academic Article
• Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases  Academic Article
• Expression and purification of recombinant mouse fibrillarin  Academic Article
• Expression of 5-lipoxygenase and leukotriene a(4) hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability  Academic Article
• Expression of APP in brains of transgenic mice containing the entire human APP gene  Academic Article
• Expression of GABA(C) receptor rho 1 and rho 2 subunits during development of the mouse retina  Academic Article
• Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis  Academic Article
• Expression of a TNF inhibitor in transgenic mice  Academic Article
• Expression of a conserved cell-type-specific protein in nerve-terminals coincides with synaptogenesis  Academic Article
• Expression of a down-regulated target, ssecks, reverses v-jun-induced transformation of 10t1/2 murine fibroblasts  Academic Article
• Expression of a noncoding rna is elevated in alzheimer's disease and drives rapid feed-forward regulation of beta-secretase  Academic Article
• Expression of a sheep red blood-cell receptor by a murine lymphoma  Academic Article
• Expression of adenoviral e3 transgenes in beta cells prevents autoimmune diabetes  Academic Article
• Expression of alkaline-phosphatase from cloned human-tumor cell-lines in human mouse somatic-cell hybrids  Academic Article
• Expression of alpha v beta 3 and alpha v beta 8 integrins during oligodendrocyte precursor differentiation in the presence and absence of axons  Academic Article
• Expression of amino-terminally truncated prp in the mouse leading to ataxia and specific cerebellar lesions  Academic Article
• Expression of an adenovirally encoded lymphotoxin-beta inhibitor prevents clearance of Listeria monocytogenes in mice  Academic Article
• Expression of c-Fes protein isoforms correlates with differentiation in myeloid leukemias  Academic Article
• Expression of chicken liver-cell adhesion molecule fusion genes in transgenic mice  Academic Article
• Expression of cytotactin in the normal and regenerating neuromuscular system  Academic Article
• Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice  Academic Article
• Expression of fibrinolytic genes in tissues from human atherosclerotic aneurysms and from obese mice  Academic Article
• Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric antiganglioside gd2 antibody  Academic Article
• Expression of h-2 antigens during growth of cultured tumor cells  Academic Article
• Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice  Academic Article
• Expression of hepatitis B virus surface and core antigens: influences of pre-S and precore sequences  Academic Article
• Expression of human apolipoprotein b90 in transgenic mice - demonstration that apolipoprotein b90 laces the structural requirements to form lipoprotein(a)  Academic Article
• Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4b promotes assembly of enzyme subunits into an active dimer  Academic Article
• Expression of human platelet glycoprotein Ib alpha in transgenic mice  Academic Article
• Expression of leukemogenic recobinant viruses associated with a recessive gene in hrs-j mice  Academic Article
• Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage  Academic Article
• Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle  Academic Article
• Expression of raf family protooncogenes in normal mouse-tissues  Academic Article
• Expression of selected antigens on surface of cultured neural cells  Academic Article
• Expression of small cytoplasmic transcripts of the rat identifier element in vivo and in cultured cells  Academic Article
• Expression of t-cell receptor genes in an antigen-specific hybridoma and radiation-induced variants  Academic Article
• Expression of the hepatitis-delta virus large and small antigens in transgenic mice  Academic Article
• Expression of the lyst(beige) mutation is atheroprotective in chow-fed apolipoprotein e-deficient mice  Academic Article
• Expression of the tumor-necrosis-factor gene by dermal fibroblasts in response to ultraviolet-irradiation or lipopolysaccharide  Academic Article
• Expression of tie receptor tyrosine kinase in leukemia-cell lines  Academic Article
• Expression of tissue factor by melanoma-cells promotes efficient hematogenous metastasis  Academic Article
• Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with Borna disease virus  Academic Article
• Expression of transforming growth factor-beta and tumor necrosis factor-alpha in the plasma and tissues of mice with lupus nephritis  Academic Article
• Expression of truncated prp targeted to purkinje cells of prp knockout mice causes purkinje cell death and ataxia  Academic Article
• Expression of type 1 plasminogen activator inhibitor in renal tissue in murine lupus nephritis  Academic Article
• Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation  Academic Article
• Expression profiling identifies genes that continue to respond to insulin in adipocytes made insulin-resistant by treatment with tumor necrosis factor-alpha  Academic Article
• Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression  Academic Article
• Expression studies of catalytic antibodies  Academic Article
• Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes  Academic Article
• Extensive oxidative DNA-damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular-carcinoma  Academic Article
• Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the alpha 5 beta 1 integrin  Academic Article
• External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos  Academic Article
• Extinction of the tumor-necrosis-factor locus, and of genes encoding the lipopolysaccharide signaling pathway  Academic Article
• Extinction partially reverts structural changes associated with remote fear memory  Academic Article
• Extracellular matrix: Functions in the nervous system  Academic Article
• Extracellular processing of peptide antigens that bind class I major histocompatibility molecules  Academic Article
• Extracellular signal regulated kinase 5 (erk5) is required for the differentiation of muscle cells  Academic Article
• Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways  Academic Article
• Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways  Academic Article
• Extraction and partial purification of the histamine-sensitizing factor of Bordetella pertussis  Academic Article
• Extrahepatic expression and regulation of protein C in the mouse  Academic Article
• Extralymphatic virus sanctuaries as a consequence of potent T-cell activation  Academic Article
• Extraneural manifestations of prion infection in gpi-anchorless transgenic mice  Academic Article
• F-box and leucine-rich repeat protein 5 (FBXL5) is required for maintenance of cellular and systemic iron homeostasis  Academic Article
• F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen  Academic Article
• FAAH genetic variation enhances fronto-amygdala function in mouse and human  Academic Article
• FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration  Academic Article
• FAN stimulates TNFα-induced gene expression, leukocyte recruitment, and humoral response  Academic Article
• FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles  Academic Article
• FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development  Academic Article
• FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy  Academic Article
• FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor  Academic Article
• FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development  Academic Article
• FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas  Academic Article
• FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation  Academic Article
• FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination  Academic Article
• Fabrication of reconfigurable protein matrices by cracking  Academic Article
• Facile generation and use of immunogenic polypeptide fusions to a sparingly soluble non-antigenic protein carrier  Academic Article
• Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice  Academic Article
• Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation  Academic Article
• Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation  Academic Article
• Factor xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1  Academic Article
• Factors limiting the immunogenicity of hiv-1 gp120 envelope glycoproteins  Academic Article
• Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex  Academic Article
• Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase: Implications for V(D)J recombination  Academic Article
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• Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation  Academic Article
• Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo  Academic Article
• Faster is not surer: a comparison of C57BL/6J and 129S2/Sv mouse strains in the watermaze  Academic Article
• Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan  Academic Article
• Fat cells directly sense temperature to activate thermogenesis  Academic Article
• Fate and plasticity of the epidermis in response to congenital activation of BRAF  Academic Article
• Fate of t-cells and b-cells transferred to scid mice  Academic Article
• Fate-restricted neural progenitors in the mammalian cerebral cortex  Academic Article
• Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task  Academic Article
• Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism  Academic Article
• Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms  Academic Article
• Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice  Academic Article
• Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice  Academic Article
• Fatty acid amide hydrolase deficiency limits early pregnancy events  Academic Article
• Fatty acid amide hydrolase determines anandamide-induced cell death in the liver  Academic Article
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• Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury  Academic Article
• Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice  Academic Article
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• Feedback repression is required for mammalian circadian clock function  Academic Article
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• Feline immunodeficiency virus vif localizes to the nucleus  Academic Article
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• Fibrillarin and other snornp proteins are targets of autoantibodies in xenobiotic-induced autoimmunity  Academic Article
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• Fibroblast growth factor 2 (Fgf2) inhibits differentiation of mesenchymal stem cells by inducing Twist2 and Spry4, blocking extracellular regulated kinase activation, and altering fgf receptor expression levels  Academic Article
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• Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha(5)beta(1) and alpha(v)beta(5)  Academic Article
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• Filopodia are required for cortical neurite initiation  Academic Article
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• Functional interactions of viral and histocompatibility antigens at tumor-cell surfaces  Academic Article
• Functional lysine modification by an intrinsically reactive primary glycolytic metabolite  Academic Article
• Functional maturation of mouse thymic lymphocytes  Academic Article
• Functional maturation of thymic lymphocyte populations in vitro  Academic Article
• Functional pharmacology of H-1 histamine receptors expressed in mouse preoptic/anterior hypothalamic neurons  Academic Article
• Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (cacna2d2)  Academic Article
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• Functional role and therapeutic implications of neuronal caspase-1 and-3 in a mouse model of traumatic spinal cord injury  Academic Article
• Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis  Academic Article
• Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination  Academic Article
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• Functional trans-inactivation of insulin receptor kinase by growth-inhibitory angiotensin ii at(2) receptor  Academic Article
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• GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease  Academic Article
• GADD4gamma regulates the thermogenic capacity of brown adipose tissue  Academic Article
• GATA family members as inducers for cellular reprogramming to pluripotency  Academic Article
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• GLUT4 expression in adipocytes regulates de novo lipogenesis and levels of a novel class of lipids with antidiabetic and anti-inflammatory effects  Academic Article
• GNE-781, a highly advanced potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP)  Academic Article
• GPIbα regulates platelet size by controlling the subcellular localization of filamin  Academic Article
• GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes  Academic Article
• GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells  Academic Article
• GPR92 as a new G12/13 and Gq-coupled lysophosphatidic acid receptor that increases cAMP: LPA5  Academic Article
• GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ  Academic Article
• GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation  Academic Article
• GSTP1 Is a driver of triple-negative breast cancer cell metabolism and pathogenicity  Academic Article
• GTPase traffic control  Academic Article
• GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation  Academic Article
• Gaba(a) receptors mediate the attenuating effects of a 5-ht(3) receptor antagonist on methamphetamine-induced behavioral sensitization in mice  Academic Article
• Gain-of-function mutational activation of human tRNA synthetase procytokine  Academic Article
• GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models  Academic Article
• Galanin message-associated polypeptide (GMAP) does not affect insulin secretion from isolated islets  Academic Article
• Galanin overexpressing transgenic mice  Academic Article
• Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge  Academic Article
• Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge  Academic Article
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• Galectin-1 and galectin-8 have redundant roles in promoting plasma cell formation  Academic Article
• Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests  Academic Article
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• Gamma delta t cell-induced hyaluronan production by epithelial cells regulates inflammation  Academic Article
• Gamma delta t cells are reduced and rendered unresponsive by hyperglycemia and chronic tnf alpha in mouse models of obesity and metabolic disease  Academic Article
• Gamma heavy chain disease in man: Independent structural abnormalities and reduced transcription of a functionally rearranged lambda L-chain gene result in the absence of L-chains  Academic Article
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• Gamma-delta-antigen receptors of thy-1+ dendritic epidermal-cells - implications for thymic differentiation  Academic Article
• Gamma-globin gene expression in chemical inducer of dimerization (cid)-dependent multipotential cells established from human beta-globin locus yeast artificial chromosome (beta-yac) transgenic mice  Academic Article
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• Ganoderma lucidum polysaccharides enhance cd14 endocytosis of lps and promote tlr4 signal transduction of cytokine expression  Academic Article
• Gap junction communication influences intercellular protein distribution in the lens  Academic Article
• Gap junctional coupling in lenses from α(8) connexin knockout mice  Academic Article
• Gap junctional coupling in lenses lacking alpha(3) connexin  Academic Article
• Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells  Academic Article
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• Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans  Academic Article
• Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice  Academic Article
• Gene expression evolves faster in narrowly than in broadly expressed mammalian genes  Academic Article
• Gene expression in mouse brain following chronic hypoxia: Role of sarcospan in glial cell death  Academic Article
• Gene expression in scrapie - cloning a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts  Academic Article
• Gene expression profile of murine long-term reconstituting vs. Short-term reconstituting hematopoietic stem cells  Academic Article
• Gene expression profiling of r6/2 transgenic mice with different cag repeat lengths reveals genes associated with disease onset and progression in huntington's disease  Academic Article
• Gene expression profiling of the olfactory tissues of sex-separated and sex-combined female and male mice  Academic Article
• Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility  Academic Article
• Gene organization and chromosome location of the neural-specific rna binding protein elavl4  Academic Article
• Gene profiling of laser-microdissected brain regions and individual cells in drug abuse and schizophrenia research  Academic Article
• Gene regulation of cell adhesion: A key step in neural morphogenesis  Academic Article
• Gene set enrichment in eqtl data identifies novel annotations and pathway regulators  Academic Article
• Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)  Academic Article
• Gene therapy for arthritis: principles and clinical practice  Academic Article
• Gene therapy for autoimmune disorders  Academic Article
• Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4  Academic Article
• Gene therapy for osteoporosis: Evaluation in a murine ovariectomy model  Academic Article
• Gene therapy for rheumatoid arthritis  Academic Article
• Gene therapy model for stromal precursor cells of hematopoietic microenvironment  Academic Article
• Gene therapy with a single chain interleukin 12 fusion protein induces t cell-dependent protective immunity in a syngeneic model of murine neuroblastoma  Academic Article
• Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCIS mouse model  Academic Article
• Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes  Academic Article
• Generation and analysis of an rna vaccine that protects against coxsackievirus b3 challenge  Academic Article
• Generation and characterization of Rgs4 mutant mice  Academic Article
• Generation and characterization of a recombinant vesicular stomatitis virus expressing the glycoprotein of Borna disease virus  Academic Article
• Generation and characterization of human monoclonal neutralizing antibodies with distinct binding and sequence features against SARS coronavirus using XenoMouse   Academic Article
• Generation and functional characterization of intracellular antibodies interacting with the kinase domain of human egf receptor  Academic Article
• Generation and phenotypic analysis of protein S-deficient mice  Academic Article
• Generation and phenotypic characterization of a galanin overexpressing mouse  Academic Article
• Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome  Academic Article
• Generation of a functional cdna-encoding the ldh2 class-i molecule by using a single-ltr retroviral shuttle vector  Academic Article
• Generation of a large combinatorial library of the immunoglobulin repertoire in phage-lambda  Academic Article
• Generation of a synthetic memory trace  Academic Article
• Generation of induced pluripotent stem cells using recombinant proteins  Academic Article
• Generation of mice derived from induced pluripotent stem cells  Academic Article
• Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells  Academic Article
• Generation of myc/fos transfectant Balb-3T3 cell lines  Academic Article
• Generation of novel rat and human pluripotent stem cells by reprogramming and chemical approaches  Academic Article
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• Generation of quorum quenching antibodies  Academic Article
• Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors  Academic Article
• Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest  Academic Article
• Genesis and evolution of antichromatin autoantibodies in murine lupus implicates t-dependent immunization with self antigen  Academic Article
• Genetic ablation of a mouse gene expressed specifically in brain  Academic Article
• Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large  Academic Article
• Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV)  Academic Article
• Genetic analysis of synaptotagmin 2 in spontaneous and ca2+-triggered neurotransmitter release  Academic Article
• Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis  Academic Article
• Genetic analysis of the corticosterone response to ethanol in bxd recombinant inbred mice  Academic Article
• Genetic and environmental regulation of the cytolytic T lymphocyte receptor repertoire specific for alloantigen  Academic Article
• Genetic and functional evidence supports LPAR1 as a susceptibility gene for hypertension  Academic Article
• Genetic and physical mapping of the Lps locus: Identification of the Toll-4 receptor as a candidate gene in the critical region  Academic Article
• Genetic and regulatory contributions of the major histocompatibility complex to the developing cytolytic T lymphocyte repertoire  Academic Article
• Genetic approaches to memory storage  Academic Article
• Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein  Academic Article
• Genetic characterization of human Dsg3-specific B cells isolated by flow cytometry from the peripheral blood of patients with pemphigus vulgaris  Academic Article
• Genetic complementation in female (BXSB x NZW)F-2 mice  Academic Article
• Genetic deficiency in pparg does not alter development of experimental prostate cancer  Academic Article
• Genetic deletion of NR3A accelerates glutamatergic synapse maturation  Academic Article
• Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum  Academic Article
• Genetic differences in behavioral sensitivity to a neuroactive steroid  Academic Article
• Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal  Academic Article
• Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice  Academic Article
• Genetic disorders associated with atp binding cassette cholesterol transporters  Academic Article
• Genetic disruption of gamma-melanocyte-stimulationg hormone signaling leads to salt-sensitive hypertension in the mouse  Academic Article
• Genetic dissection of innate immunity to infection: The mouse cytomegalovirus model  Academic Article
• Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis  Academic Article
• Genetic diversity of murine rheumatoid factors  Academic Article
• Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens  Academic Article
• Genetic factors influence cataract formation in α(3) connexin knockout mice  Academic Article
• Genetic informational rna is not required for recombinant prion infectivity  Academic Article
• Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes  Academic Article
• Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes  Academic Article
• Genetic loss of FAAH compromises male fertility in mice  Academic Article
• Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling  Academic Article
• Genetic modulation of T cell receptor gene segment usage during somatic recombination  Academic Article
• Genetic reassortants of lymphocytic choriomeningitis virus - unexpected disease and mechanism of pathogenesis  Academic Article
• Genetic regulation of behavioral and neuronal responses to fluoxetine  Academic Article
• Genetic regulation of commitment to interleukin 4 production by a cd4(+) t cell-intrinsic mechanism  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). I. H-2 restriction of the murine humoral immune response to the a and d determinants of HBsAg  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). II. Qualitative characteristics of the humoral immune response to the a, d, and y determinants of HBsAg  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). III. Circumvention of nonresponsiveness in mice bearing HBsAg nonresponder haplotypes  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions  Academic Article
• Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). VI. T cell fine specificity  Academic Article
• Genetic reprogramming of tumor cells by zinc finger transcription factors  Academic Article
• Genetic risk prediction and neurobiological understanding of alcoholism  Academic Article
• Genetic studies in systemic autoimmunity and aging  Academic Article
• Genetic studies of auto-immunity and retrovirus expression in crosses of new-zealand black mice .2. Viral envelope glycoprotein gp70  Academic Article
• Genetic susceptibility to silver-induced anti-fibrillarin autoantibodies in mice  Academic Article
• Genetic-control of immunoglobulin-synthesis  Academic Article
• Genetic-regulation of the immune-response to hepatitis-b surface-antigen (hbsag) .5. T-cell proliferative response and cellular interactions  Academic Article
• Genetical genomics: spotlight on QTL hotspots  Academic Article
• Genetically encoded and post-translationally modified forms of a major histocompatibility complex class i-restricted antigen bearing a glycosylation motif are independently processed and co-presented to cytotoxic t lymphocytes  Academic Article
• Genetically encoded chemical probes in cells reveal the binding path of Urocortin-I to CRF class B GPCR  Academic Article
• Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis  Academic Article
• Genetics of SLE in mice  Academic Article
• Genetics of systemic autoimmunity and glomerulonephritis in mouse models of lupus  Academic Article
• Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming  Academic Article
• Genome wide analysis of inbred mouse lines identifies a locus containing ppar-gamma as contributing to enhanced malaria survival  Academic Article
• Genome-wide analysis of CREB target genes reveals a core promoter requirement for camp responsiveness  Academic Article
• Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins  Academic Article
• Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling  Academic Article
• Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links  Academic Article
• Genome-wide gain-of-function screen identifies novel regulators of pluripotency  Academic Article
• Genome-wide gene expression analysis identifies K-ras as a regulator of alcohol intake  Academic Article
• Genome-wide gene expression profiles of the developing mouse hippocampus  Academic Article
• Genome-wide haplotype association mapping in mice identifies a genetic variant in cer1 associated with bmd and fracture in southern chinese women  Academic Article
• Genome-wide identification of bcl11b gene targets reveals role in brain-derived neurotrophic factor signaling  Academic Article
• Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse  Academic Article
• Genomewide association analysis in diverse inbred mice: Power and population structure  Academic Article
• Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system  Academic Article
• Genomic and biological variation among commonly used lymphocytic choriomeningitis virus-strains  Academic Article
• Genomic characterization of the lysophosphatidic acid receptor gene, lPA2/Edg4, and identification of a frameshift mutation in a previously characterized cDNA  Academic Article
• Genomic composition and allelic polymorphisms influence-V-beta usage by the mycoplasma-arthritidis superantigen  Academic Article
• Genomic organization and expression of b-cell and t-cell antigen receptor genes in murine lupus  Academic Article
• Genomic organization and sequence of t-cell receptor beta-chain constant-region and joining-region genes  Academic Article
• Germline deletion of Igh 3 ' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus  Academic Article
• Germline diversity within the mouse igk-v9 gene family  Academic Article
• Germline exclusion of Cks1 in the mouse reveals a metaphase I role for Cks proteins in male and female meiosis  Academic Article
• Ghrelin and growth hormone secretagogue receptor expression in mice during aging  Academic Article
• Ghrelin is dispensable for embryonic pancreatic islet development and differentiation  Academic Article
• Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants  Academic Article
• Ghrelin partially protects against cisplatin-induced male murine gonadal toxicity in a GHSR-1a-dependent manner  Academic Article
• Ghrelin prevents cisplatin-induced testicular damage by facilitating repair of DNA double strand breaks through activation of p53 in mice  Academic Article
• Ghrelin promotes thymopoiesis during aging  Academic Article
• Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging  Academic Article
• Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor  Academic Article
• Ginsenoside Re rescues methamphetamine-induced oxidative damage, mitochondrial dysfunction, microglial activation, and dopaminergic degeneration by inhibiting the protein kinase Cδ gene  Academic Article
• Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates alzheimer's disease-related neuropathies: Involvement of non-amyloidogenic processing  Academic Article
• Girk channel modulation by assembly with allosterically regulated RGS proteins  Academic Article
• Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition  Academic Article
• Glial ephrin-a3 regulates hippocampal dendritic spine morphology and glutamate transport  Academic Article
• Glial membranes at the node of Ranvier prevent neurite outgrowth  Academic Article
• Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis  Academic Article
• Glioma-induced remodeling of the neurovascular unit  Academic Article
• Glioma-propagating cells as an in vitro screening platform: PLK1 as a case study  Academic Article
• Global analysis of posttranslational protein arginylation  Academic Article
• Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters  Academic Article
• Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects  Academic Article
• Global effects of mistranslation from an editing defect in mammalian cells  Academic Article
• Global gene expression analysis of the developing postnatal mouse retina  Academic Article
• Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution  Academic Article
• Global profiling of dynamic protein palmitoylation  Academic Article
• Glomerular and renal vascular structural changes in alpha 8 integrin-deficient mice  Academic Article
• Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity  Academic Article
• Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms  Academic Article
• Glucosamine activates autophagy in vitro and in vivo  Academic Article
• Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes  Academic Article
• Glucose-dependent activation of bacillus anthracis toxin gene expression and virulence requires the carbon catabolite protein ccpa  Academic Article
• Glutamate activates NF-kappa B through calpain in neurons  Academic Article
• Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter  Academic Article
• Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development  Academic Article
• Glycan microarray of globo h and related structures for quantitative analysis of breast cancer  Academic Article
• Glycans on influenza hemagglutinin affect receptor binding and immune response  Academic Article
• Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells  Academic Article
• Glycolipid and ganglioside metabolism imbalances in huntington's disease  Academic Article
• Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin  Academic Article
• Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d/NKT cell pathway  Academic Article
• Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells  Academic Article
• Gold causes genetically determined autoimmune and immunostimulatory responses in mice  Academic Article
• Gold- and silver-induced murine autoimmunity - requirement for cytokines and cd28 in murine heavy metal-induced autoimmunity  Academic Article
• Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis  Academic Article
• Growth and differentiation of prechondrogenic cells on bioactive self-assembled peptide nanofibers  Academic Article
• Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate  Academic Article
• Growth hormone corrects proliferation and transcription of phosphoenolpyruvate carboxykinase in livers of old mice via elimination of CCAAT/enhancer-binding protein alpha-Brm complex  Academic Article
• Growth hormone secretagogue receptor (GHS-R1a) knockout mice exhibit improved spatial memory and deficits in contextual memory  Academic Article
• Growth of epithelial-cells in the thymic medulla is under the control of mature t-cells  Academic Article
• Gu81, a vegfr2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine mmtv-pymt transgenic model of breast cancer  Academic Article
• Guided corona generates wettability patterns that selectively direct cell attachment inside closed microchannels  Academic Article
• Guinea pig beta(1C)-globulin: its relationship to the third component of complement and its alteration following interaction with immune complexes  Academic Article
• Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2  Academic Article
• H7N9 influenza virus neutralizing antibodies that possess few somatic mutations  Academic Article
• HBsAg retention sensitizes the hepatocyte to injury by physiological concentrations of interferon‐γ  Academic Article
• HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model  Academic Article
• HDAC2 negatively regulates memory formation and synaptic plasticity  Academic Article
• HDAC4 governs a transcriptional program essential for synaptic plasticity and memory  Academic Article
• HDL induces no-dependent vasorelaxation via the lysophospholipid receptor S1P(3)  Academic Article
• HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export  Academic Article
• HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production  Academic Article
• HIV displays its coat of arms  Academic Article
• HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection  Academic Article
• HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest  Academic Article
• HMGB factors are required for posterior digit development through integrating signaling pathway activities  Academic Article
• HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria  Academic Article
• Ha novel approach to investigate tissue-specific trinucleotide repeat instability  Academic Article
• Habenular alpha 5 nicotinic receptor subunit signalling controls nicotine intake  Academic Article
• Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger  Academic Article
• Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase  Academic Article
• Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone  Academic Article
• Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response  Academic Article
• Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation  Academic Article
• Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior  Academic Article
• Haploinsufficiency for odc modifies mouse skin tumor susceptibility  Academic Article
• Hard top soft bottom microfluidic devices for cell culture and chemical analysis  Academic Article
• Harmonics of circadian gene transcription in mammals  Academic Article
• Harmonin mutations cause mechanotransduction defects in cochlear hair cells  Academic Article
• Harnessing cyanine reactivity for optical imaging and drug delivery  Academic Article
• Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines  Academic Article
• Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis  Academic Article
• Harnessing the fcμ receptor for potent and selective cytotoxic therapy of chronic lymphocytic leukemia  Academic Article
• Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells  Academic Article
• Heat shock protein 70 is required for optimal liver regeneration after partial hepatectomy in mice  Academic Article
• Heavy chain V gene-specific elimination of B cells during the pre-B cell to B cell transition  Academic Article
• Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells  Academic Article
• Helicobacter pylori infection modifies gastric and plasma ghrelin dynamics in Mongolian gerbils  Academic Article
• Helix 11 dynamics is critical for constitutive androstane receptor activity  Academic Article
• Helper T lymphocytes from xid and normal mice support anti-phosphocholine antibody responses with equivalent T15, 511, and 603 idiotypic composition  Academic Article
• Hematopoietic differentiation of embryonic stem cells  Academic Article
• Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins b cell linker protein and slp-76 in lymphocytes  Academic Article
• Hematopoietic stem cell gene therapy for the multisystemic lysosomal storage disorder cystinosis  Academic Article
• Hematopoietic tissue factor-protease-activated receptor 2 signaling promotes hepatic inflammation and contributes to pathways of gluconeogenesis and steatosis in obese mice  Academic Article
• Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway  Academic Article
• Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition  Academic Article
• Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms  Academic Article
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• Hemostatic gene expression and vascular disease in obesity: insights from studies of genetically obese mice  Academic Article
• HepG2 cells infected with Klebsiella pneumoniae show DNA laddering at apoptotic and necrotic stages  Academic Article
• Hepatic glucose sensing via the CREB coactivator CRTC2  Academic Article
• Hepatic preneoplasia in hepatitis-B virus transgenic mice  Academic Article
• Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1- 3 n-acetylglucosamine linkages  Academic Article
• Hepatitis B small surface antigen particles are octahedral  Academic Article
• Hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice  Academic Article
• Hepatitis B virus RNA-binding proteins associated with cytokine-induced clearance of viral RNA from the liver of transgenic mice  Academic Article
• Hepatitis B virus replication is cell cycle independent during liver regeneration in transgenic mice  Academic Article
• Hepatitis B virus transgenic mice: Models of viral immunobiology and pathogenesis  Academic Article
• Hepatitis C virus core and E2 protein expression in transgenic mice  Academic Article
• Hepatitis-B virus gene-expression in transgenic mice  Academic Article
• Hepatitis-B virus immunopathogenesis  Academic Article
• Hepatitis-B virus nucleocapsid particles do not cross the hepatocyte nuclear-membrane in transgenic mice  Academic Article
• Hepatitis-B virus transgenic mice - insights into the virus and the disease  Academic Article
• Hepatocarcinogenesis due to chronic liver-cell injury in hepatitis-B virus transgenic mice  Academic Article
• Hepatocyte nuclear factor-4-independent synthesis of coagulation factor vii in breast cancer cells and its inhibition by targeting selective histone acetyltransferases  Academic Article
• Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication  Academic Article
• Heterochromatin protein HP1Hsbeta (p25beta) and its localization with centromeres in mitosis  Academic Article
• Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages  Academic Article
• Heterogeneity among Epstein-Barr virus-seropositive donors in the generation of immunoblastic B-cell lymphomas in SCID mice receiving human peripheral blood leukocyte grafts  Academic Article
• Heterogeneity of t-cell receptor usage in experimental autoimmune neuritis in the lewis rat  Academic Article
• Heterogeneity of tremor mechanisms assessed by tremor-related cortical potential in mice  Academic Article
• Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia  Academic Article
• Heterosubtypic antibodies to influenza A virus have limited activity against cell-bound virus but are not impaired by strain-specific serum antibodies  Academic Article
• Heterotransplantation of two human lymphoid cell lines transformed in vitro by epstein-barr virus  Academic Article
• Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation  Academic Article
• High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies  Academic Article
• High anti-TNP plaque-forming cell potential of residual mIg+ cells in a T cell population  Academic Article
• High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes  Academic Article
• High prion and prpsc levels but delayed-onset of disease in scrapie-inoculated mice heterozygous for a disrupted prp gene  Academic Article
• High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIb alpha-filamin interaction  Academic Article
• High spatial resolution imaging of endogenous hydrogen peroxide in living cells by solid-state fluorescence  Academic Article
• High-affinity consensus binding of target RNAs by the STAR/GSG proteins GLS-1, STAR-2 and quaking  Academic Article
• High-affinity ligand probes of cd22 overcome the threshold set by cis ligands for binding, endocytosis, and killing of b cells  Academic Article
• High-density lipoprotein stimulates myocardial perfusion in vivo  Academic Article
• High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor  Academic Article
• High-level hepatitis-B virus-replication in transgenic mice  Academic Article
• High-level lipoprotein a expression in transgenic mice: Evidence for oxidized phospholipids in lipoprotein a but not in low density lipoproteins  Academic Article
• High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy  Academic Article
• High-resolution assessment of protein DNA binding affinity and selectivity utilizing a fluorescent intercalator displacement (FID) assay  Academic Article
• High-resolution fluorescence microscope imaging of erythroblast structure  Academic Article
• High-resolution functional proteomics by active-site peptide profiling  Academic Article
• High-resolution mutational profiling suggests the genetic validity of glioblastoma patient-derived pre-clinical models  Academic Article
• High-resolution nucleosome mapping of targeted regions using BAC-based enrichment  Academic Article
• High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase  Academic Article
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• High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations  Academic Article
• High-throughput morphometric analysis of individual neurons  Academic Article
• High-throughput quantitative histological analysis of alzheimer's disease pathology using a confocal digital microscanner  Academic Article
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• Human CD8 transgene regulation of HLA recognition by murine T cells  Academic Article
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• Human autoantibody recognition of DNA  Academic Article
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• Human gene essentiality  Academic Article
• Human immunodeficiency virus infection of human cells transplanted to severe combined immunodeficient mice  Academic Article
• Human immunodeficiency virus infection of human-PBL-SCID mice  Academic Article
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• Human immunodeficiency virus type 1 infection of neonatal severe combined immunodeficient mice xenografted with human cord blood cells  Academic Article
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• Human pancreatic beta-like cells converted from fibroblasts  Academic Article
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• Human pluripotent stem cells: decoding the naïve state  Academic Article
• Human recombinant antimannan immunoglobulin g1 antibody confers resistance to hematogenously disseminated candidiasis in mice  Academic Article
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• Identification of small-molecule inducers of pancreatic β-cell expansion  Academic Article
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• Immune response of mice, rabbits and cattle to inactivated Mycoplasma mycoides subspecies Mycoides vaccines containing adjuvants  Academic Article
• Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization  Academic Article
• Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus  Academic Article
• Immune system-dependent and -independent replication of the scrapie agent  Academic Article
• Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10  Academic Article
• Immune tolerance split between hepatitis B virus precore and core proteins  Academic Article
• Immune versus natural selection: Antibody aldolases with enzymic rates but broader scope  Academic Article
• Immune-complexes can trigger specific, t-cell-dependent, autoanti-igg antibody-production in mice  Academic Article
• Immune-complexes in cancer - demonstration of complexes in mice bearing neuroblastomas  Academic Article
• Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice  Academic Article
• Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes  Academic Article
• Immunization of hu-pbl-scid mice and the rescue of human monoclonal fab fragments through combinatorial libraries  Academic Article
• Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity  Academic Article
• Immunization with the gene expressing woodchuck hepatitis virus nucleocapsid protein fused to cytotoxic-T-lymphocyte-associated antigen 4 leads to enhanced specific immune responses in mice and woodchucks  Academic Article
• Immunobiology and pathogenesis of hepatocellular injury in hepatitis-B virus transgenic mice  Academic Article
• Immunobiology of Epstein-Barr virus-associated lymphomas  Academic Article
• Immunobiology of the autoantibody response. I. Circulating analogues of erythrocyte autoantigens and heterogeneity of the autoimmune response of NZB mice  Academic Article
• Immunobiology of the autoantibody response. II. The lipoprotein-associated soluble HB erythrocyte autoantigen of NZB mice  Academic Article
• Immunochemical characterization of human-tumor antigens  Academic Article
• Immunochemical heterogeneity of human-plasma high-density lipoproteins - identification with apolipoprotein a-i-specific and a-ii-specific monoclonal-antibodies  Academic Article
• Immunochemical termination of self-tolerance  Academic Article
• Immunochemistry of the dominating antigenic region ala582 to cys604 in the transmembranous protein of simian and human immunodeficiency virus  Academic Article
• Immunocytochemical demonstration of neural cell-adhesion molecule (ncam) along the migration route of luteinizing-hormone-releasing hormone (lhrh) neurons in mice  Academic Article
• Immunocytokines: A new approach to immunotherapy of melanoma  Academic Article
• Immunocytokines: A promising approach to cancer immunotherapy  Academic Article
• Immunodeficient mice xenografted with human lymphoid cells: new models for in vivo studies of human immunobiology and infectious diseases  Academic Article
• Immunodetection of cell-bound antigens using both mouse and human monoclonal-antibodies  Academic Article
• Immunodominance in virus-induced cd8(+) t-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon  Academic Article
• Immunoelectronmicroscopy of neural antigens on ultrathin frozen-sections  Academic Article
• Immunogenic peptides corresponding to the dominant antigenic region alanine-597 to cysteine-619 in the transmembrane protein of simian immunodeficiency virus have a propensity to fold in aqueous solution  Academic Article
• Immunogenic stability of heat-killed Mycoplasma mycoides subsp. Mycoides at 4 degrees C  Academic Article
• Immunogenicity and partial-purification of soluble h-2 antigens extracted with hypertonic salt  Academic Article
• Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: Implications for immunotherapy of persistent viral infections  Academic Article
• Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: Identification of an H2-Kd-restricted CTL epitope  Academic Article
• Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines  Academic Article
• Immunoglobulin gene rearrangement in b-cell deficient mice generated by targeted deletion of the j(h) locus  Academic Article
• Immunoglobulin-g - functional sites  Academic Article
• Immunoglobulin-kappa light chain variable region gene-complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice  Academic Article
• Immunoglobulins can utilize riboflavin (vitamin b2) to activate the antibody-catalyzed water oxidation pathway  Academic Article
• Immunohistochemical analysis of the development of somatostatin in the reeler neocortex  Academic Article
• Immunologic and biochemical properties of the histamine-sensitizing factor from Bordetella pertussis  Academic Article
• Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris  Academic Article
• Immunologic effects of an orally available BRAFV600E inhibitor in BRAF wild-type murine models  Academic Article
• Immunological and pathological consequences of coxsackievirus RNA persistence in the heart  Academic Article
• Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies  Academic Article
• Immunological basis of resistance to RL-male-1 induced by immunoselected Thy-1.2 negative variants  Academic Article
• Immunological detection of thymidine photoproduct formation in vivo  Academic Article
• Immunological disease induced by injecting F1 lymphoid cells into certain parental strains  Academic Article
• Immunological effects of neonatal infection with mouse thymic virus  Academic Article
• Immunological functions of lymphocytes fractionated with antigen-derivatized fibers  Academic Article
• Immunological relation of basement membrane and a serum beta globulin in the mouse. Demonstration of renal basement membrane alteration in mice injected with streptolysin S  Academic Article
• Immunological tumor destruction in a murine melanoma model by targeted lt alpha independent of secondary lymphoid tissue  Academic Article
• Immunology of muscarinic acetylcholine and beta-adrenergic catecholamine receptors  Academic Article
• Immunology: Toll-like receptors and antibody responses  Academic Article
• Immunomodulation and the quorum sensing molecule 3-oxo-C-12-homoserine lactone: The importance of chemical scaffolding for probe development  Academic Article
• Immunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation  Academic Article
• Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling  Academic Article
• Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (balb-c times nzb)f1 mice by scripps leukemia virus  Academic Article
• Immunopathology and pathogenesis of cutaneous involvement in systemic lupus erythematosus  Academic Article
• Immunopathology of adoptive immunization in mice chronically infected with lymphocytic choriomeningitis virus  Academic Article
• Immunopharmacotherapeutic manifolds and modulation of cocaine overdose  Academic Article
• Immunoproteasome-deficient mice mount largely normal cd8(+) t cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination  Academic Article
• Immunoselection of structural H-2Kb variants: use of cloned cytolytic T cells to select for loss of a CTL-defined allodeterminant  Academic Article
• Immunostimulatory DNA sequences necessary for effective intradermal gene immunization  Academic Article
• Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase  Academic Article
• Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells  Academic Article
• Immunosuppressive and autoimmune effects of thimerosal in mice  Academic Article
• Immunosuppressive effects of 3-methylcholanthrene given intratracheally in various inbred strains of mice  Academic Article
• Immunosuppressive effects of glucosamine  Academic Article
• Immunosuppressive effects of subglutinol derivatives  Academic Article
• Immunosurveillance of the liver by intravascular effector CD8(+) T cells  Academic Article
• Immunotherapy for virus-infection  Academic Article
• Immunotherapy of a murine colon cancer with syngeneic spleen-cells, immune rna and tumor-antigen  Academic Article
• Immunotherapy with a posttranscriptionally modified DNA vaccine induces complete protection against metastatic neuroblastoma  Academic Article
• Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells  Academic Article
• Impact of C4'-O-alkyl linker on in vivo pharmacokinetics of near-infrared cyanine/monoclonal antibody conjugates  Academic Article
• Impact of distinct chemical structures for the development of a methamphetamine vaccine  Academic Article
• Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice  Academic Article
• Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function  Academic Article
• Impact of sleep and circadian disruption on energy balance and diabetes: a summary of workshop discussions  Academic Article
• Impact of somatic mutation on the S107(T15) heavy-chain V region of antibodies reactive with self and nonself  Academic Article
• Impact of substituents in tumor uptake and fluorescence imaging ability of near-infrared cyanine-like dyes  Academic Article
• Impact of sugar stereochemistry on natural killer T cell stimulation by bacterial glycolipids  Academic Article
• Impact of β2 integrin deficiency on mouse natural killer cell development and function  Academic Article
• Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein  Academic Article
• Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice  Academic Article
• Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome  Academic Article
• Impaired immunoproteasome assembly and immune responses in pa28(-/-) mice  Academic Article
• Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice  Academic Article
• Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain  Academic Article
• Impaired lymphopoiesis and altered b cell subpopulations in mice overexpressing lnk adaptor protein  Academic Article
• Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system  Academic Article
• Impaired microrna processing causes corpus luteum insufficiency and infertility in mice  Academic Article
• Impaired negative regulation of homeostatically proliferating T cells  Academic Article
• Impaired prion replication in spleens of mice lacking functional follicular dendritic cells  Academic Article
• Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin  Academic Article
• Impaired water maze learning performance in mu-opioid receptor knockout mice  Academic Article
• Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis  Academic Article
• Impairment of dopaminergic system function after chronic treatment with corticotropin-releasing factor  Academic Article
• Impairment of spatial but not contextual memory in camkii mutant mice with a selective loss of hippocampal ltp in the range of the theta-frequency  Academic Article
• Importance of cellular microenvironment and circulatory dynamics in b cell immunotherapy  Academic Article
• Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection  Academic Article
• Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers  Academic Article
• Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant  Academic Article
• Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist  Academic Article
• In a transgenic model of spontaneous autoimmune diabetes, expression of a protective class II MHC molecule results in thymic deletion of diabetogenic CD8+ T cells  Academic Article
• In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages  Academic Article
• In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness  Academic Article
• In silico qtl mapping of basal liver iron levels in inbred mouse strains  Academic Article
• In situ click chemistry: Enzyme inhibitors made to their own specifications  Academic Article
• In situ cytokine therapy: Redistribution of clonally expanded t cells  Academic Article
• In situ measurement of solute transport in the bone lacunar-canalicular system  Academic Article
• In situ selection of lead compounds by click chemistry: Target-guided optimization of acetylcholinesterase inhibitors  Academic Article
• In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics  Academic Article
• In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the alpha 6 beta 4 integrin and dystroglycan  Academic Article
• In vitro and in vivo anticancer activity of a synthetic glycolipid as Toll-like receptor 4 (TLR4) activator  Academic Article
• In vitro and in vivo neurotoxicity of prion protein oligomers  Academic Article
• In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi  Academic Article
• In vitro construction of a b-tropic virus by recombination - b-tropism is a cryptic phenotype of xenotropic murine retroviruses  Academic Article
• In vitro dendritic cell infection by pseudotyped adenoviral vectors does not correlate with their in vivo immunogenicity  Academic Article
• In vitro detection of cells infected with lactic dehydrogenase virus (LDV) by fluorescein-labeled antibody to LDV  Academic Article
• In vitro drug testing using hemopoietic cells: goals and limitations  Academic Article
• In vitro functional-characterization of sag-3 - a naturally-occurring monoclonal-antibody in nzb mice - specificity toward functional t-cell subsets  Academic Article
• In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots  Academic Article
• In vitro responses of CBA/N mice: spleen cells of mice with an X-linked defect that precludes immune responses to several thymus-independent antigens can respond to TNP-lipopolysaccharide  Academic Article
• In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library  Academic Article
• In vitro studies of the genetically determined unresponsiveness to thymus-independent antigens in CBA/N mice  Academic Article
• In vitro transformation of murine bone marrow cells with a v-raf/v-myc retrovirus yields clonally related mature b cells and macrophages  Academic Article
• In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses  Academic Article
• In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation  Academic Article
• In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire  Academic Article
• In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease  Academic Article
• In vivo accumulation of t cells in response to il-2/anti-il-2 mab complexes is dependent in part on the tnf family ligand 4-1bbl  Academic Article
• In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, mk-826 (l-749,345)  Academic Article
• In vivo activity in a catalytic antibody-prodrug system: antibody catalyzed etoposide prodrug activation for selective chemotherapy  Academic Article
• In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance  Academic Article
• In vivo and in vitro production of anti-histone antibodies in NZB/NZW mice  Academic Article
• In vivo and in vitro studies on the potentiation of muscarinic receptor stimulation by alaproclate, a selective 5-HT uptake blocker  Academic Article
• In vivo anergized T cells form altered immunological synapses in vitro  Academic Article
• In vivo brain GPCR signaling elucidated by phosphoproteomics  Academic Article
• In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons  Academic Article
• In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects  Academic Article
• In vivo cleavage of alpha 2,6-sialyltransferase by alzheimer beta-secretase  Academic Article
• In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated beta1 integrin and induction of FAK/PI3K/Akt motility signaling  Academic Article
• In vivo complementation of complex i by the yeast ndi1 enzyme - possible application for treatment of parkinson disease  Academic Article
• In vivo conversion of bm plasmacytoid dc into cd11b(+) conventional dc during virus infection  Academic Article
• In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides  Academic Article
• In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I  Academic Article
• In vivo efficacy of natural product-inspired irreversible kinase inhibitors  Academic Article
• In vivo efficacy of novel synthetic enediynes 1  Academic Article
• In vivo expansion of t reg cells with il-2-mab complexes: Induction of resistance to eae and long-term acceptance of islet allografts without immunosuppression  Academic Article
• In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes  Academic Article
• In vivo expression of human growth hormone by genetically modified murine bone marrow stromal cells and its effect on the cells in vitro  Academic Article
• In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection  Academic Article
• In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers  Academic Article
• In vivo imaging of hepcidin promoter stimulation by iron and inflammation  Academic Article
• In vivo interrogation of the molecular display of atherosclerotic lesion surfaces  Academic Article
• In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function  Academic Article
• In vivo osteopontin-induced macrophage accumulation is dependent on CD44 expression  Academic Article
• In vivo potent BM635 analogue with improved drug-like properties  Academic Article
• In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models  Academic Article
• In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation  Academic Article
• In vivo regulation of crkii and crkl proto-oncogenes in the uterus by insulin-like growth factor-i - differential effects on tyrosine phosphorylation and association with paxillin  Academic Article
• In vivo regulation of hepatitis B virus replication by peroxisome proliferators  Academic Article
• In vivo relevance for platelet glycoprotein Ib alpha residue Tyr276 in thrombus formation  Academic Article
• In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice  Academic Article
• In vivo selection for metastasis promoting genes in the mouse  Academic Article
• In vivo stabilization of mutant human transthyretin in transgenic mice  Academic Article
• In vivo suppression of the primary immune response by a species of low density serum lipoprotein  Academic Article
• In vivo targeting of b-cell lymphoma with glycan ligands of cd22  Academic Article
• In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors  Academic Article
• In vivo treatment with a mhc class i-restricted blocking peptide can prevent virus-induced autoimmune diabetes  Academic Article
• In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line  Academic Article
• In vivo-activated cd4 t cells upregulate cxc chemokine receptor 5 and reprogram their response to lymphoid chemokines  Academic Article
• In-frame TCR delta-gene rearrangements play a critical role in the alpha-beta/gamma-delta T-cell lineage decision  Academic Article
• Inability of il-2 and il-10 to counteract b-cell clonal deletion  Academic Article
• Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers  Academic Article
• Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging  Academic Article
• Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids  Academic Article
• Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1  Academic Article
• Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1  Academic Article
• Inactivation of macrophage nitric oxide synthase activity by ng-methyl-l-arginine  Academic Article
• Inactivation of pkc theta leads to increased susceptibility to obesity and dietary insulin resistance in mice  Academic Article
• Inactivation of the 5-ht7 receptor partially blocks phencyclidine-induced disruption of prepulse inhibition  Academic Article
• Inactivation of the p53 pathway in retinoblastoma  Academic Article
• Inactivation of thiol-dependent enzymes by hypothiocyanous acid: Role of sulfenyl thiocyanate and sulfenic acid intermediates  Academic Article
• Incomplete T-cell receptor V-beta allelic exclusion and dual V-beta-expressing cells  Academic Article
• Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: Generation of antibodies against the thrombin-sensitive region of murine protein S  Academic Article
• Incorporation of phosphonate into benzonaphthyridine toll-like receptor 7 agonists for adsorption to aluminum hydroxide  Academic Article
• Incorporation of the purified epstein-barr virus/c3d receptor (cr-2) into liposomes and demonstration of its dual ligand-binding functions  Academic Article
• Increase of anti-metastatic efficacy by selectivity-but not affinity-optimization of synthetic serine protease inhibitors  Academic Article
• Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal  Academic Article
• Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A  Academic Article
• Increased c-fos expression in the central nucleus of the amygdala and enhancement of cued fear memory in dyt1 delta gag knock-in mice  Academic Article
• Increased drinking during withdrawal from intermittent ethanol exposure is blocked by the CRF receptor antagonist D-Phe-CRF(12-41)  Academic Article
• Increased endothelial expression of toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events  Academic Article
• Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice  Academic Article
• Increased ethanol self-administration in delta-opioid receptor knockout mice  Academic Article
• Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies  Academic Article
• Increased expression of fibronectin and the alpha 5 beta 1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia  Academic Article
• Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction  Academic Article
• Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "klotho" mouse  Academic Article
• Increased expression of the beta 4 and alpha 5 integrin subunits in cerebral blood vessels of transgenic mice chronically producing the pro-inflammatory cytokines il-6 or ifn-alpha, in the central nervous system  Academic Article
• Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice  Academic Article
• Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance  Academic Article
• Increased hyperalgesia after tissue injury and faster recovery of allodynia after nerve injury in the GalR1 knockout mice  Academic Article
• Increased immune response variability during simultaneous viral coinfection leads to unpredictability in CD8 T cell immunity and pathogenesis  Academic Article
• Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta(-/-) mice  Academic Article
• Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7α-hydroxylase  Academic Article
• Increased response to morphine in mice lacking protein kinase c epsilon  Academic Article
• Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase  Academic Article
• Increased spectrin proteolysis in the brindled mouse-brain  Academic Article
• Increased survival and reduced neutrophil infiltration of the liver in Rab27a-but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation  Academic Article
• Increased survival times of new-zealand hybrid mice immunosuppressed by graft versus host reactions  Academic Article
• Increased susceptibility to DNA virus infection in mice with a GCN2 mutation  Academic Article
• Increased thrombogenesis and embolus formation in mice lacking glycoprotein V  Academic Article
• Increased yield of antibody-producing murine spleen-cell hybridomas from fusions cultured in medium supplemented with mouse serum  Academic Article
• Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation  Academic Article
• Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia  Academic Article
• Increasing t-cell age reduces effector activity but preserves proliferative capacity in a murine allogeneic major histocompatibility complex - mismatched bone marrow transplant model  Academic Article
• Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality  Academic Article
• Increasing the chemical potential of the germ-line antibody repertoire  Academic Article
• Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of EphB2 and neuronal activity  Academic Article
• Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization  Academic Article
• Individual V-H promoters vary in strength, but the frequency of rearrangement of those V-H genes does not correlate with promoter strength nor enhancer-independence  Academic Article
• Individually programmable cell stretching microwell arrays actuated by a Braille display  Academic Article
• Indoleamine 2,3-dioxygenase expression in trans-planted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes  Academic Article
• Induced pluripotent stem cells free of exogenous reprogramming factors  Academic Article
• Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses  Academic Article
• Inducible and reversible gene expression with the rtta system for the study of memory  Academic Article
• Inducible control of gene expression with destabilized Cre  Academic Article
• Inducible expression of the long pentraxin PTX3 in the central nervous system  Academic Article
• Inducible gene expression in mammalian cells and transgenic mice  Academic Article
• Inducible nitric oxide synthase: Role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction  Academic Article
• Induction and rapid expression of an immune response in vitro  Academic Article
• Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules  Academic Article
• Induction of B cell priming by neonatal injection of mice with thymic-independent (type 2) antigens  Academic Article
• Induction of B lymphocyte proliferation by monoclonal anti-Lyb 2 antibody  Academic Article
• Induction of CD44 expression by the Epstein-Barr virus latent membrane protein LMP1 is associated with lymphoma dissemination  Academic Article
• Induction of a pharmacologically active clonotypic b-cell response directed to an immunogenic region of the human beta-2-adrenergic receptor  Academic Article
• Induction of allogeneic cytolytic T lymphocytes by partially purified membrane glycoproteins  Academic Article
• Induction of an antibody that catalyzes the hydrolysis of an amide bond  Academic Article
• Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12  Academic Article
• Induction of antiviral antibodies by DNA immunization requires neither perforin-mediated nor cd8(+)-t-cell-mediated lysis of antigen-expressing cells  Academic Article
• Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded microRNA-15a  Academic Article
• Induction of c-fos mRNA in the arcuate nucleus of normal and mutant growth hormone-deficient mice by a synthetic non-peptidyl growth hormone secretagogue  Academic Article
• Induction of c-fos messenger-rna and ap-1 DNA-binding activity by camp in cooperation with either the adenovirus 243-amino or the adenovirus 289-amino acid e1a protein  Academic Article
• Induction of hematopoietic microenvironment by the extracellular matrix from long-term bone marrow cultures  Academic Article
• Induction of high serum levels of retroviral env gene-products (gp70) in mice by bacterial lipopolysaccharide  Academic Article
• Induction of igg antibodies by an anti-idiotype antibody mimicking disialoganglioside gd2  Academic Article
• Induction of interferon-gamma inducing factor in the adrenal cortex  Academic Article
• Induction of minor alloantigen-specific T cell subsets in vivo: recognition of processed antigen by helper but not by cytotoxic T cell precursors  Academic Article
• Induction of monocyte procoagulant activity by murine hepatitis-virus type-3 parallels disease susceptibility in mice  Academic Article
• Induction of murine autoimmune-disease by chronic polyclonal b-cell activation  Academic Article
• Induction of nitrite/nitrate synthesis in murine macrophages by bcg infection, lymphokines, or interferon-gamma  Academic Article
• Induction of ornithine decarboxylase by il-3 is mediated by sequential c-myc-independent and c-myc-dependent pathways  Academic Article
• Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3  Academic Article
• Induction of persistent tumor-protective immunity in mice cured of established colon carcinoma metastases  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in adipocytes by thiazolidinediones  Academic Article
• Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha  Academic Article
• Induction of pluripotency in mouse somatic cells with lineage specifiers  Academic Article
• Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds  Academic Article
• Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2  Academic Article
• Induction of pregnancy during established EAE halts progression of CNS autoimmune injury via pregnancy-specific serum factors  Academic Article
• Induction of retinal progenitors and neurons from mammalian Müller glia under defined conditions  Academic Article
• Induction of rheumatoid antibodies in the mouse - regulated production of autoantibody in the secondary humoral response  Academic Article
• Induction of severe autoimmune-disease in normal mice by simultaneous action of multiple immunostimulators  Academic Article
• Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice  Academic Article
• Induction of systemic autoimmunity by a xenobiotic requires endosomal TLR trafficking and signaling from the late endosome and endolysosome but not type I IFN  Academic Article
• Induction of the early growth response (Egr) family of transcription factors during thymic selection  Academic Article
• Induction of transcription factor ap-1 by adenovirus e1a-protein and camp  Academic Article
• Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice  Academic Article
• Induction of type-i interferon genes and interferon-inducible genes in embryonal stem-cells devoid of interferon regulatory factor-i  Academic Article
• Infected cd8 alpha(-) dendritic cells are the predominant source of il-10 during establishment of persistent viral infection  Academic Article
• Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice  Academic Article
• Infection control by antibody disruption of bacterial quorum sensing signaling  Academic Article
• Infection of lymphocytes by a virus that aborts cytotoxic lymphocyte-t activity and establishes persistent infection  Academic Article
• Infection with a recombinant vaccinia virus encoding myelin proteolipid protein causes suppression of chronic relapsing-remitting experimental allergic encephalomyelitis  Academic Article
• Infection with vaccinia favors the selection of hybridomas synthesizing autoantibodies against intermediate filaments, one of them cross-reacting with the virus hemagglutinin  Academic Article
• Infectious rna isolated from the spinal cords of mice chronically infected with theiler's murine encephalomyelitis virus  Academic Article
• Infectivity in mouse fibroblasts of polyoma DNA integrated into plasmid pBR322 or lambdoid phage DNA  Academic Article
• Infectivity of scrapie prions bound to a stainless steel surface  Academic Article
• Inflammasome activation by cystine crystals: implications for the pathogenesis of cystinosis  Academic Article
• Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity  Academic Article
• Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger  Academic Article
• Inflammation in atherosclerosis - lesion formation in ldl receptor-deficient mice with perforin and lyst(beige) mutations  Academic Article
• Inflammation, obesity, and thrombosis  Academic Article
• Inflammatory cells in solid murine neoplasms. I. Tumor disaggregation and identification of constituent inflammatory cells  Academic Article
• Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression  Academic Article
• Inflammatory cytokines: Putative regulators of neuronal and neuro-endocrine function  Academic Article
• Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice  Academic Article
• Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer  Academic Article
• Influence of antigen on a model for analysis of multiple coordinate events associated with the primary immune-response  Academic Article
• Influence of coding-end sequence on coding-end processing in V(D)J recombination  Academic Article
• Influence of the N-terminal domain on the aggregation properties of the prion protein  Academic Article
• Influence of the immunoregulatory serum lipoprotein LDL-In on the in vivo proliferation and differentiation of antigen-binding and antibody-secreting lymphocytes during a primary immune response  Academic Article
• Influence of the major histocompatibility complex on the repertoire of allospecific cytolytic T lymphocytes  Academic Article
• Influence of threonine metabolism on S-adenosylmethionine and histone methylation  Academic Article
• Influence of thymic genotype on the systemic lupus erythematosus-like disease and t-cell proliferation of mrl-mp-lpr-lpr mice  Academic Article
• Influencing uptake and localization of aminoglycoside-functionalized peptoids  Academic Article
• Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I  Academic Article
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• Inhibition by mk-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice  Academic Article
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• Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4  Academic Article
• Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task  Academic Article
• Inhibition of hepatitis B virus in mice by RNA interference  Academic Article
• Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice  Academic Article
• Inhibition of hepatitis B virus replication during schistosoma mansoni infection in transgenic mice  Academic Article
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• Inhibition of immunological injury of cultured-cells infected with lymphocytic choriomeningitis virus - role of defective interfering virus in regulating viral antigenic expression  Academic Article
• Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice  Academic Article
• Inhibition of lipopolysaccharide activation of 70z/3 cells by anti-lipopolysaccharide antibodies  Academic Article
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• Inhibition of matrix metalloproteinase 9 activation by a specific monoclonal antibody  Academic Article
• Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway  Academic Article
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• Inhibition of monoacylglycerol lipase reduces nicotine withdrawal  Academic Article
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• Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance  Academic Article
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• Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate  Academic Article
• Inhibition of t-cell proliferation and sle-like syndrome of mrl-1 mice by whole-body or total lymphoid irradiation  Academic Article
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• Inhibition of tissue factor signaling suppresses tumor growth  Academic Article
• Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor  Academic Article
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• Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice  Academic Article
• Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice  Academic Article
• Inhibitory effects of mk-801 on contextual sensitization to climbing behavior and on development of tolerance to hypothermia induced by a single high dose of apomorphine  Academic Article
• Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling  Academic Article
• Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome  Academic Article
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• Inositol pyrophosphates pyrotechnics  Academic Article
• Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling  Academic Article
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• Integrated regulation of toll-like receptor responses by notch and interferon-gamma pathways  Academic Article
• Integration of cardiac proteome biology and medicine by a specialized knowledgebase  Academic Article
• Integration of deoxyribonucleic acid specific for rous-sarcoma virus after infection of permissive and nonpermissive hosts  Academic Article
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• Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity  Academic Article
• Integrative analysis of low- and high-resolution eqtl  Academic Article
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• Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy  Academic Article
• Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes  Academic Article
• Ksa antigen ep-cam mediates cell-cell adhesion of pancreatic epithelial cells: Morphoregulatory roles in pancreatic islet development  Academic Article
• Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination  Academic Article
• Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis  Academic Article
• Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature  Academic Article
• L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity  Academic Article
• LACTB is a tumour suppressor that modulates lipid metabolism and cell state  Academic Article
• LC3-dependent intracellular membrane tubules induced by gamma-protocadherins A3 and B2: a role for intraluminal interactions  Academic Article
• LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome  Academic Article
• LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element  Academic Article
• LP-BM5 murine retrovirus-induced immunodeficiency disease in allogeneic SCID chimeric mice. Inability to recognize a putative viral superantigen does not prevent induction of disease  Academic Article
• LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage  Academic Article
• LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation  Academic Article
• LPA1 receptor activation promotes renal interstitial fibrosis  Academic Article
• LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation  Academic Article
• LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA)  Academic Article
• LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation  Academic Article
• LRP5 is required for vascular development in deeper layers of the retina  Academic Article
• LXR-mediated inhibition of CD4(+) T helper cells  Academic Article
• LY2875358, a neutralizing and internalizing anti-MET bivalent antibody, inhibits HGF-dependent and HGF-independent MET activation and tumor growth  Academic Article
• La autoantigen specifically recognizes a predicted stem-loop in hepatitis B virus RNA  Academic Article
• Labeling and comparative biodistribution of the monoclonal antibody ks1/4 in nude mice bearing human lung adenocarcinoma  Academic Article
• Lack of N-regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences  Academic Article
• Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis  Academic Article
• Lack of class-I H-2-antigens in cells transformed by radiation leukemia-virus is associated with methylation and rearrangement of H-2 DNA  Academic Article
• Lack of correlation between loss of anchorage-independent growth and levels of transformation-specific p53 protein in retinoic acid-treated F9 embryonal carcinoma cells  Academic Article
• Lack of evidence for central T-cell tolerance defects in lupus mice and for V-beta-deleting endogenous superantigens in rats and humans  Academic Article
• Lack of intrinsic ctla-4 expression has minimal effect on regulation of antiviral t-cell immunity  Academic Article
• Lack of mu-opioid receptor leads to an increase in the nmda receptor subunit mrna expression and nmda-induced convulsion  Academic Article
• Lack of prion infectivity in fixed heart tissue from patients with Creutzfeldt-Jakob disease or amyloid heart disease  Academic Article
• Lack of pseudotype formation between human immunodeficiency virus type 1 and Epstein-Barr virus in productively coinfected B lymphoblastoid cell lines  Academic Article
• Lack of relationship between serum gp70 levels and the severity of systemic lupus-erythematosus in mrl/1 mice  Academic Article
• Lack of reward and locomotor stimulation induced by heroin in mu-opioid receptor-deficient mice  Academic Article
• Lack of self-administration of cocaine in dopamine d-1 receptor knock-out mice  Academic Article
• Lack of sterol regulatory element binding factor-1c imposes glial Fatty Acid utilization leading to peripheral neuropathy  Academic Article
• Lack of stimulant and anxiolytic-like effects of ethanol and accelerated development of ethanol dependence in mu-opioid receptor knockout mice  Academic Article
• Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7e3 glycoprotein iib/iiia platelet antibody  Academic Article
• Lacrimal gland inflammation deregulates extracellular matrix remodeling and alters molecular signature of epithelial stem/progenitor cells  Academic Article
• Lactational and postnatal exposure to polychlorinated biphenyls induces sex-specific anxiolytic behavior and cognitive deficit in mice offspring  Academic Article
• Lactic dehydrogenase virus-induced immune complex type of glomerulonephritis  Academic Article
• Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration  Academic Article
• Lambda interferon inhibits hepatitis B and C virus replication  Academic Article
• Laminin stimulates spreading of platelets through integrin alpha(6)beta(1)-dependent activation of GPVI  Academic Article
• Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction  Academic Article
• Large-scale analysis of the human and mouse transcriptomes  Academic Article
• Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures  Academic Article
• Large-scale profiling of Rab GTPase trafficking networks: the membrome  Academic Article
• Late administration of monoclonal-antibody to leukocyte function-antigen 1 abrogates incipient murine cerebral malaria  Academic Article
• Late treatment with polyene antibiotics can prolong the survival time of scrapie-infected animals  Academic Article
• Late-onset corticohippocampal neurodepletion attributable to catastrophic failure of oxidative phosphorylation in MILON mice  Academic Article
• Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (sigma r1)  Academic Article
• Lateral diffusion of surface molecules in animal-cells and tissues  Academic Article
• Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins  Academic Article
• Lcmv-specific, class-ii restricted cytotoxic t-cells in beta-2-microglobulin deficient mice  Academic Article
• Lead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials  Academic Article
• Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors  Academic Article
• Lead optimization of antimalarial propafenone analogues  Academic Article
• Leakage-free bonding of porous membranes into layered microfluidic array systems  Academic Article
• Learned recognition of maternal signature odors mediates the first suckling episode in mice  Academic Article
• Learning impairment in transgenic mice with central overexpression of corticotropin-releasing factor  Academic Article
• Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response  Academic Article
• Leiomodins: larger members of the tropomodulin (Tmod) gene family  Academic Article
• Lentiviral gene delivery of vmip-ii to transplanted endothelial cells and endothelial progenitors is proangiogenic in vivo  Academic Article
• Leptin enhances the potency of circulating angiogenic cells via src kinase and integrin alpha v beta 5: implications for angiogenesis in human obesity  Academic Article
• Leptin promotes vascular remodeling and neointimal growth in mice  Academic Article
• Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity  Academic Article
• Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism  Academic Article
• Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza  Academic Article
• Lethal alpha-thalassemia created by gene targeting in mice and its genetic rescue  Academic Article
• Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet  Academic Article
• Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV)  Academic Article
• Leu5enkephalin-encoding sequences are targets for a specific DNA-binding factor.  Academic Article
• Leu628 of the kix domain of cbp is a key residue for the interaction with the mll transactivation domain  Academic Article
• Leukocyte cd11b expression is not essential for the development of atherosclerosis in mice  Academic Article
• Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM)  Academic Article
• Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size  Academic Article
• Leukocyte-derived hepatic lipase increases hdl and decreases en face aortic atherosclerosis in ldlr-/- mice expressing cetp  Academic Article
• Leukotriene C synthase in mouse mastocytoma cells. An enzyme distinct from cytosolic and microsomal glutathione transferases  Academic Article
• Leukotriene C4 synthase: characterization in mouse mastocytoma cells  Academic Article
• Lhx1 maintains synchrony among circadian oscillator neurons of the SCN  Academic Article
• Library construction for next-generation sequencing: overviews and challenges  Academic Article
• Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor  Academic Article
• Ligand-induced internalization of the epidermal growth-factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors  Academic Article
• Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo  Academic Article
• Like-acetylglucosaminyltransferase (large)-dependent modification of dystroglycan at thr-317/319 is required for laminin binding and arenavirus infection  Academic Article
• Limited diversity of t-cell receptor gamma-chain expression of murine thy-1+ dendritic epidermal-cells revealed by v-gamma-3-specific monoclonal-antibody  Academic Article
• Limited functional diversity in kappa-light-chains - junctional sequences from CD43(+)B220(+) early B-cell progenitors resemble those from peripheral B-cells  Academic Article
• Limited proliferative potential of primitive hematopoietic stem cells: hematopoiesis by clonal succession  Academic Article
• Limiting the available t-cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology  Academic Article
• Limits of a deletion spanning Tlr4 in C57BL/10ScCr mice  Academic Article
• Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro  Academic Article
• Linear padre t helper epitope and carbohydrate b cell epitope conjugates induce specific high titer igg antibody responses  Academic Article
• Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes  Academic Article
• Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression  Academic Article
• Lipid binding promotes oligomerization and focal adhesion activity of vinculin  Academic Article
• Lipid tucaresol as an adjuvant for methamphetamine vaccine development  Academic Article
• Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors  Academic Article
• Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappa B independently of platelet-activating factor  Academic Article
• Lipopolysaccharide induces hyporesponsiveness to its own action in raw 2647 cells  Academic Article
• Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2  Academic Article
• Lipopolysaccharide sensing an important factor in the innate immune response to gram-negative bacterial infections: Benefits and hazards of lps hypersensitivity  Academic Article
• Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway  Academic Article
• Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock  Academic Article
• Lipopolysaccharide-induced il-12 expression in the central nervous system and cultured astrocytes and microglia  Academic Article
• Lipopolysaccharide-treated RAW 264.7 cells produce a mediator that inhibits lipoprotein lipase in 3T3-L1 cells  Academic Article
• Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium  Academic Article
• Lipoproteins inhibit macrophage activation by lipoteichoic acid  Academic Article
• Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct  Academic Article
• Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene  Academic Article
• Liposomal packaging generates Wnt protein with in vivo biological activity  Academic Article
• Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs  Academic Article
• Liquid chromatography-fourier transform ion cyclotron resonance mass spectrometric characterization of protein kinase c phosphorylation  Academic Article
• Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile x syndrome  Academic Article
• Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells  Academic Article
• Live cell calcium imaging of dissociated vomeronasal neurons  Academic Article
• Liver (b-type) phosphofructokinase messenger-rna - cloning, structure, and expression  Academic Article
• Liver autoimmunity triggered by microbial activation of natural killer T cells  Academic Article
• Liver capsule: Age-influenced hepatic immune priming determines HBV infection fate: Implications from mouse to man  Academic Article
• Liver is liver and blood is blood, and finally the twain have met  Academic Article
• Liver x receptor and retinoic x receptor mediated abca1 regulation and cholesterol efflux in macrophage cells - messenger rna measured by branched DNA technology  Academic Article
• Liver x receptor-retinoid x receptor (lxr-rxr) heterodimer cistrome reveals coordination of lxr and ap1 signaling in keratinocytes  Academic Article
• Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing  Academic Article
• Lkb1 and sad kinases define a pathway required for the polarization of cortical neurons  Academic Article
• Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling  Academic Article
• Local not systemic modulation of dendritic cell s1p receptors in lung blunts virus-specific immune responses to influenza  Academic Article
• Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina  Academic Article
• Localization and substrate selectivity of sea urchin multidrug (MDR) efflux transporters  Academic Article
• Localization at high-resolution of antibody-induced mobilization of vaccinia virus hemagglutinin and the major histocompatibility antigens on the plasma-membrane of infected-cells  Academic Article
• Localization of 2 epitopes of apolipoprotein-a-i that are exposed on human high-density lipoproteins using monoclonal-antibodies and synthetic peptides  Academic Article
• Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as neural signaling molecules  Academic Article
• Localization of a passively transferred human recombinant monoclonal antibody to herpes simplex virus glycoprotein D to infected nerve fibers and sensory neurons in vivo  Academic Article
• Localization of a stable neural correlate of associative memory  Academic Article
• Localization of an apolipoprotein-a-i epitope critical for activation of lecithin-cholesterol acyltransferase  Academic Article
• Localization of an apolipoprotein-a-i epitope critical for lipoprotein-mediated cholesterol efflux from monocytic cells  Academic Article
• Localization of cholesterol, amyloid and glia in alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (tof-sims) and immunofluorescence imaging  Academic Article
• Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression  Academic Article
• Localization of sarcomeric proteins during myofibril assembly in cultured mouse primary skeletal myotubes  Academic Article
• Localization of the beta(beta)(3)-adrenoceptor in the human gastrointestinal tract: An immunohistochemical study  Academic Article
• Localization of the binding-site for the human high-affinity fc receptor on igg  Academic Article
• Localization of the human jun protooncogene to chromosome region 1p31-32  Academic Article
• Localization of the monocyte-binding region on human immunoglobulin-g  Academic Article
• Localization of tumor necrosis factor receptor messenger rna in normal and herpes simplex virus infected mouse eyes  Academic Article
• Locally synchronized synaptic inputs  Academic Article
• Loci predisposing to autoimmunity in MRL-Fas(lpr) and C57BL/6-Fas(lpr) mice  Academic Article
• Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels  Academic Article
• Loganin improves learning and memory impairments induced by scopolamine in mice  Academic Article
• Long latency event-related potentials in mice: Effects of stimulus characteristics and strain  Academic Article
• Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling  Academic Article
• Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy  Academic Article
• Long-term growth suppression of human glioma xenografts by chemoimmunoconjugates of 4-desacetylvinblastine-3-carboxyhydrazide and monoclonal-antibody 9.2.27  Academic Article
• Long-term monitoring of circadian rhythms in c-fos gene expression from suprachiasmatic nucleus cultures  Academic Article
• Long-term persistence and reactivation of t cell memory in the lung of mice infected with respiratory syncytial virus  Academic Article
• Long-term phorbol ester treatment down-regulates the beta(3)-adrenergic receptor in 3t3-f442a adipocytes  Academic Article
• Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions  Academic Article
• Long-term xenogeneic chimeras - full differentiation of rat t-cells and b-cells in scid mice  Academic Article
• Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract  Academic Article
• Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation  Academic Article
• Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids  Academic Article
• Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope  Academic Article
• Loss of bax alters tumor spectrum and tumor numbers in arf-deficient mice  Academic Article
• Loss of histaminergic modulation of thermoregulation and energy homeostasis in obese mice  Academic Article
• Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells  Academic Article
• Loss of lysophosphatidic acid receptor LPA(1) alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex  Academic Article
• Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human β-amyloid precursor protein  Academic Article
• Loss of nicotine-induced behavioral sensitization in mu-opioid receptor knockout mice  Academic Article
• Loss of p53 compensates for alpha(v)-integrin function in retinal neovascularization  Academic Article
• Loss of retinal cadherin facilitates mammary tumor progression and metastasis  Academic Article
• Loss of sex discrimination and male-male aggression in mice deficient for trp2  Academic Article
• Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome  Academic Article
• Loss of spinal substance P pain transmission under the condition of LPA1 receptor-mediated neuropathic pain  Academic Article
• Loss of t cell and b cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in gimap5-deficient mice  Academic Article
• Loss of the amino-terminal helix-loop-helix domain of the vav protooncogene activates its transforming potential  Academic Article
• Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer  Academic Article
• Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance  Academic Article
• Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease  Academic Article
• Loss-of-function mutations of ildr1 cause autosomal-recessive hearing impairment dfnb42  Academic Article
• Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies  Academic Article
• Low doses of DNP-D-GL, a potent hapten-specific tolerogen, are immunogenic in vitro  Academic Article
• Low-affinity cytotoxic t-lymphocytes require ifn-gamma to clear an acute viral infection  Academic Article
• Lp-211 is a brain penetrant selective agonist for the serotonin 5-ht(7) receptor  Academic Article