subject area of
- "Viral deja vu" elicits organ-specific immune disease independent of reactivity to self Academic Article
- 'Two-stage double-technique hybrid (TSDTH)' identification strategy for the analysis of BMP2-induced transdifferentiation of premyoblast C2C12 cells to osteoblast Academic Article
- (18)F-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils Academic Article
- -Amino acid substitution of peptide-mediated NF-κB suppression in mdx mice preserves therapeutic benefit in skeletal muscle, but causes kidney toxicity Academic Article
- 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation Academic Article
- 1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia Academic Article
- 11-deoxy prostaglandin F(2 alpha), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(-/-) females Academic Article
- 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination Academic Article
- 1B1075: a brain- and pituitary-specific mRNA that encodes a novel chromogranin/secretogranin-like component of intracellular vesicles Academic Article
- 2-Amino- 1,2,4 triazolo 1,5-a pyridines as JAK2 inhibitors Academic Article
- 2-Aminobenzimidazoles as potent Aurora kinase inhibitors Academic Article
- 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases Academic Article
- 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of beta-amyloid aggregation Academic Article
- 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution Academic Article
- 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies Academic Article
- 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 1 Academic Article
- 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 2 Academic Article
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)pi perazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth Academic Article
- 4-Aminoindazolyl-dihydrofuro 3,4-d pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase Academic Article
- 4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency Academic Article
- 5,6-methanoleukotriene A(4): a potent specific inhibitor for 5-lipoxygenase Academic Article
- 5-HT(1A) receptor binding in the dorsal raphe nucleus is implicated in the anxiolytic-like effects of Cinnamomum cassia Academic Article
- 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission Academic Article
- 5-HT(7) receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern Academic Article
- 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor alpha-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent Academic Article
- 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103) Academic Article
- 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2 Academic Article
- 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience Academic Article
- 8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents Academic Article
- 8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors Academic Article
- A 1,064 bp fragment from the promoter region of the Col11a2 gene drives LacZ expression not only in cartilage but also in osteoblasts adjacent to regions undergoing both endochondral and intramembranous ossification in mouse embryos Academic Article
- A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells Academic Article
- A 46-nucleotide promoter segment from an IFN-alpha gene renders an unrelated promoter inducible by virus Academic Article
- A 5' leader of Rbm3, a cold stress-induced mRNA, mediates internal initiation of translation with increased efficiency under conditions of mild hypothermia Academic Article
- A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity Academic Article
- A CAT reporter construct allows ultrasensitive estimation of TNF synthesis, and suggests that the TNF gene has been silenced in non-macrophage cell lines Academic Article
- A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells Academic Article
- A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response Academic Article
- A CreER mouse to study melanin concentrating hormone signaling in the developing brain Academic Article
- A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth Academic Article
- A DNA vaccine targeting fos-related antigen 1 enhanced by il-18 induces long-lived t-cell memory against tumor recurrence Academic Article
- A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication Academic Article
- A DNA-based cancer vaccine enhances lymphocyte cross talk by engaging the nkg2d receptor Academic Article
- A FAAH-regulated class of N-acyl taurines that activates TRP ion channels Academic Article
- A Gja8 (Cx50) point mutation causes an alteration of α3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice Academic Article
- A Jekyll and Hyde profile: Type 1 interferon signaling plays a prominent role in the initiation and maintenance of a persistent virus infection Academic Article
- A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids Academic Article
- A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells Academic Article
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis Academic Article
- A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate Academic Article
- A Protective Strategy against Hyperinflammatory Responses Requiring the Nontranscriptional Actions of GPS2 Academic Article
- A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum Academic Article
- A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice Academic Article
- A T cell receptor-specific blockade of positive selection Academic Article
- A THEMIS:SHP1 complex promotes T-cell survival Academic Article
- A TRP channel that senses cold stimuli and menthol Academic Article
- A ZAP-70 kinase domain variant prevents thymocyte- positive selection despite signalling CD69 induction Academic Article
- A binding site for homeodomain and pax proteins is necessary for l1 cell adhesion molecule gene expression by pax-6 and bone morphogenetic proteins Academic Article
- A binding site for pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord Academic Article
- A biparatopic HER2-targeting antibody-drug conjugate induces tumor regression in primary models refractory to or ineligible for HER2-targeted therapy Academic Article
- A brain detoxifying enzyme for organophosphorus nerve poisons Academic Article
- A candidate circuit approach to investigating autism Academic Article
- A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation Academic Article
- A catechol-O-methyltransferase that is essential for auditory function in mice and humans Academic Article
- A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1) Academic Article
- A cell-autonomous requirement for the cell cycle regulatory protein, rb, in neuronal migration Academic Article
- A cellular gene encodes scrapie prp 27-30 protein Academic Article
- A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis Academic Article
- A ceramide-1-phosphate analogue, pcera-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages Academic Article
- A change in the conformation of prions accompanies the emergence of a new prion strain Academic Article
- A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins Academic Article
- A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor Academic Article
- A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (ppar alpha) versus liver x receptor Academic Article
- A chemically induced vaccine strategy for prostate cancer Academic Article
- A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase Academic Article
- A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses Academic Article
- A chimeric mouse model of Gaucher disease Academic Article
- A combinatorial system for cloning and expressing the catalytic antibody repertoire in escherichia-coli Academic Article
- A common and unstable copy number variant is associated with differences in glo1 expression and anxiety-like behavior Academic Article
- A common antiviral cytotoxic lymphocyte-t epitope for diverse major histocompatibility complex haplotypes - implications for vaccination Academic Article
- A common solution to group 2 influenza virus neutralization Academic Article
- A comparative analysis of the immunological evolution of antibody 28B4 Academic Article
- A comparative encyclopedia of DNA elements in the mouse genome Academic Article
- A comparison of 129S2/SvHsd and C57BL/6JO1aHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically modified mice Academic Article
- A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis Academic Article
- A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models Academic Article
- A comparison of t cell memory against the same antigen induced by virus versus intracellular bacteria Academic Article
- A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis Academic Article
- A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol Academic Article
- A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells Academic Article
- A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform Academic Article
- A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses Academic Article
- A conserved Val to Ile switch near the heme pocket of animal and bacterial nitric-oxide synthases helps determine their distinct catalytic profiles Academic Article
- A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase Academic Article
- A conserved motif in the itk ph-domain is required for phosphoinositide binding and tcr signaling but dispensable for adaptor protein interactions Academic Article
- A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function Academic Article
- A cost-effective fluorescence mini-microscope for biomedical applications Academic Article
- A critical evaluation of a nicotine vaccine within a self-administration behavioral model Academic Article
- A critical role for the sphingosine analog aal-r in dampening the cytokine response during influenza virus infection Academic Article
- A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics Academic Article
- A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling Academic Article
- A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy Academic Article
- A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response Academic Article
- A curly-tail modifier locus, mct1, on mouse chromosome-17 Academic Article
- A customized self-assembling peptide hydrogel for dental pulp tissue engineering Academic Article
- A derivative of the melanocortin receptor antagonist shu9119 (pg932) increases food intake when administered peripherally Academic Article
- A designer AAV variant permits efficient retrograde access to projection neurons Academic Article
- A developmental influence of the N-methyl-D-aspartate receptor NR3A subunit on prepulse inhibition of startle Academic Article
- A direct GABAergic output from the basal ganglia to frontal cortex Academic Article
- A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification Academic Article
- A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d Academic Article
- A distribution-free test for tumor-growth curve analyses with application to an animal tumor-immunotherapy experiment Academic Article
- A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use Academic Article
- A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+) CD8(+) thymocytes Academic Article
- A double-stranded rna-activated protein kinase-dependent pathway mediating stress-induced apoptosis Academic Article
- A dual role for microglia in promoting tissue inhibitor of metalloproteinase (timp) expression in glial cells in response to neuroinflammatory stimuli Academic Article
- A dual-function DNA vaccine encoding carcinoembryonic antigen and cd40 ligand trimer induces t cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice Academic Article
- A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis Academic Article
- A dynamic search process underlies microRNA targeting Academic Article
- A dystroglycan mutation associated with limb-girdle muscular dystrophy Academic Article
- A factor IX-deficient mouse model for hemophilia B gene therapy Academic Article
- A family of leukemia inhibitory factor-binding peptides that can act as antagonists when conjugated to poly(ethylene glycol) Academic Article
- A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange Academic Article
- A five-amino-acid motif in the undefined region of the tlr8 ectodomain is required for species-specific ligand recognition Academic Article
- A fluorescent plate reader assay for ceramide kinase Academic Article
- A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome Academic Article
- A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity Academic Article
- A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function Academic Article
- A fragment of human TrpRS as a potent antagonist of ocular angiogenesis Academic Article
- A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells Academic Article
- A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen Academic Article
- A functional genomics strategy reveals Rora as a component of the mammalian circadian clock Academic Article
- A functional hot spot for antigen recognition in a superagonist TCR/MHC complex Academic Article
- A functional interaction between RIP140 and PGC-1 alpha regulates the expression of the lipid droplet protein CIDEA Academic Article
- A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding Academic Article
- A gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesity Academic Article
- A gene atlas of the mouse and human protein-encoding transcriptomes Academic Article
- A gene encoding an intestinal-enriched member of the Kruppel-like factor family expressed in intestinal epithelial cells Academic Article
- A genetic analysis of lupus Academic Article
- A genetic approach to the generation of antibodies with enhanced catalytic activities Academic Article
- A genetic determinant of the striatal dopamine response to alcohol in men Academic Article
- A genetic determinant that specifically regulates the frequency of hematopoietic stem cells Academic Article
- A genetic marker in the variable region of light chains of mouse immunoglobulins Academic Article
- A genetic-locus regulates the expression of tissue-specific messenger-rnas from multiple transcription units Academic Article
- A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing Academic Article
- A genetically humanized mouse model for hepatitis C virus infection Academic Article
- A genomic screen for activators of the antioxidant response element Academic Article
- A genomic screen identifies TYRO3 as a MITF regulator in melanoma Academic Article
- A gfp-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse Academic Article
- A global map of lipid-binding proteins and their ligandability in cells Academic Article
- A glycoengineered enzyme with multiple mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes Academic Article
- A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival Academic Article
- A heat-modifiable outer-membrane protein carries an antigen specific for the species Yersinia-enterocolitica and Yersinia-pseudotuberculosis Academic Article
- A heat-sensitive TRP channel expressed in keratinocytes Academic Article
- A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain Academic Article
- A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis Academic Article
- A highly conserved neutralizing epitope on group 2 influenza a viruses Academic Article
- A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia Academic Article
- A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature Academic Article
- A hormone-dependent module regulating energy balance Academic Article
- A human aminoacyl-tRNA synthetase as a regulator of angiogenesis Academic Article
- A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo Academic Article
- A human recombinant monoclonal antibody to cocaine: preparation, characterization and behavioral studies Academic Article
- A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol Academic Article
- A human-brain glycoprotein related to the mouse-cell adhesion molecule l1 Academic Article
- A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy Academic Article
- A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus Academic Article
- A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen Academic Article
- A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters Academic Article
- A keratinocyte-responsive gamma delta tcr is necessary for dendritic epidermal t cell activation by damaged keratinocytes and maintenance in the epidermis Academic Article
- A key role for lipoic acid synthesis during Plasmodium liver stage development Academic Article
- A kinetic aggregation assay allowing selective and sensitive amyloid-β quantification in cells and tissues Academic Article
- A lack of mu-opioid receptors modulates the expressions of neuropeptide y and substance p mrna Academic Article
- A large noncoding rna is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas Academic Article
- A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells Academic Article
- A legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis Academic Article
- A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status Academic Article
- A leukocyte homologue of the il-8 receptor cxcr-2 mediates the accumulation of macrophages in atherosclerotic lesions of ldl receptor-deficient mice Academic Article
- A liver-selective LXR inverse agonist that suppresses hepatic steatosis Academic Article
- A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses Academic Article
- A mRNA variant encoding a soluble form of 4-1BB, a member of the murine NGf/TNF receptor family Academic Article
- A major conformational change in p97 aaa atpase upon atp binding Academic Article
- A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells Academic Article
- A metabolomics strategy for detecting protein-metabolite interactions to identify natural nuclear receptor ligands Academic Article
- A method for rapid mouse siderocyte enrichment Academic Article
- A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting Academic Article
- A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids Academic Article
- A minimally lipidated form of cell-derived apolipoprotein e exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins Academic Article
- A minor catalytic activity of src family kinases is sufficient for maximal activation of mast cells via the high-affinity ige receptor Academic Article
- A mitochondrial targeting two-channel responsive fluorescence probe for imaging the superoxide radical anion in vitro and in vivo Academic Article
- A model for familial exudative vitreoretinopathy caused by LPR5 mutations Academic Article
- A model of measles virus-induced immunosuppression: Enhanced susceptibility of neonatal human pbls Academic Article
- A model of the cell-autonomous mammalian circadian clock Academic Article
- A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells Academic Article
- A molecular link between the active component of marijuana and Alzheimer's disease pathology Academic Article
- A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3 Academic Article
- A molecular switch controls interspecies prion disease transmission in mice Academic Article
- A monoclonal-antibody directed against the beta-1-adrenergic receptor from turkey erythrocyte-membranes Academic Article
- A monoclonal-antibody specific for conidia and mycelium wall layer of penicillium and aspergillus Academic Article
- A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration Academic Article
- A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons Academic Article
- A mouse model for nonsyndromic deafness (dfnb12) links hearing loss to defects in tip links of mechanosensory hair cells Academic Article
- A mouse model of accelerated liver aging caused by a defect in DNA repair Academic Article
- A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice Academic Article
- A multifunctional bispecific antibody protects against Pseudomonas aeruginosa Academic Article
- A multivalent minigene vaccine, containing b-cell, cytotoxic t-lymphocyte, and t-h epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen Academic Article
- A multivalent vaccination strategy for the prevention of old world arenavirus infection in humans Academic Article
- A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response Academic Article
- A murine t-cell receptor gene-complex - isolation, structure and rearrangement Academic Article
- A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen Academic Article
- A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα Academic Article
- A near-IR uncaging strategy based on cyanine photochemistry Academic Article
- A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA exhibits predominant expression in the hypothalamus, thalamus and amygdala of mouse forebrain Academic Article
- A new approach to high-sensitivity differential hybridization Academic Article
- A new method of embryonic culture for assessing global changes in brain organization Academic Article
- A new murine CD4+ T cell subset with an unrestricted cytokine profile Academic Article
- A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis Academic Article
- A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity Academic Article
- A nonapoptotic role for BAX and BAK in eicosanoid metabolism Academic Article
- A novel 2 '-(n-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models Academic Article
- A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma Academic Article
- A novel ELISA for mouse activated protein C in plasma Academic Article
- A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target Academic Article
- A novel Netrin-l-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching Academic Article
- A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease Academic Article
- A novel allele of myosin viia reveals a critical function for the c-terminal ferm domain for melanosome transport in retinal pigment epithelial cells Academic Article
- A novel and simple method for culturing pericytes from mouse brain Academic Article
- A novel approach for in vivo measurement of mouse red cell redox status Academic Article
- A novel approach for monitoring extracellular acidification rates: based on bead injection spectrophotometry and the lab-on-valve system Academic Article
- A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis Academic Article
- A novel class II MHC molecule with unusual tissue distribution Academic Article
- A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties Academic Article
- A novel cross-talk in diacylglycerol signaling the rac-gap beta 2-chimaerin is negatively regulated by protein kinase c delta-mediated phosphorylation Academic Article
- A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1 Academic Article
- A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects Academic Article
- A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis Academic Article
- A novel generation of heparan sulfate mimetics for the treatment of prion diseases Academic Article
- A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation Academic Article
- A novel method for generating region-specific monoclonal-antibodies to modified proteins - application to the identification of human glucosylated low-density lipoproteins Academic Article
- A novel method to establish microglia-free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia Academic Article
- A novel monoclonal antibody, L1A3, is directed to the functional site of the αv integrin subunit Academic Article
- A novel neuron-specific DNA end-binding factor in the murine brain Academic Article
- A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action Academic Article
- A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease Academic Article
- A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β Academic Article
- A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal cns Academic Article
- A novel synthetic bipartite carrier protein for developing glycotope-based vaccines Academic Article
- A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system Academic Article
- A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines Academic Article
- A novel vascular endothelial growth factor heparin-binding domain substructure binds to glycosaminoglycans in vivo and localizes to tumor microvascular endothelium Academic Article
- A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests Academic Article
- A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct Academic Article
- A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects Academic Article
- A pRb-responsive, RGD-modified, and Hyaluronidase-armed Canine Oncolytic Adenovirus for Application in Veterinary Oncology Academic Article
- A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity Academic Article
- A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration Academic Article
- A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas Academic Article
- A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects Academic Article
- A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice Academic Article
- A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones Academic Article
- A peripheral and central t-cell antigen recognized by a monoclonal thymocytotoxic autoantibody from new-zealand black mice Academic Article
- A phage display approach for rapid antibody humanization: designed combinatorial V gene libraries Academic Article
- A phase i/ib trial of murine monoclonal anti-gd2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma - a report of the children's cancer group Academic Article
- A phase-i study of human mouse chimeric antiganglioside gd2 antibody ch14.18 in patients with neuroblastoma Academic Article
- A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins Academic Article
- A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia Academic Article
- A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein Academic Article
- A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase ii in t cells: From activation to unresponsiveness Academic Article
- A plaque-specific antibody clears existing beta-amyloid plaques in Alzheimer's disease mice Academic Article
- A platform stratifying a sequestering agent and a pharmacological antagonist as a means to negate botulinum neurotoxicity Academic Article
- A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice Academic Article
- A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding Academic Article
- A population of murine gamma delta T cells that recognize an inducible MHC class Ib molecule Academic Article
- A porous silicon-based optical interferometric biosensor Academic Article
- A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic Academic Article
- A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis Academic Article
- A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo Academic Article
- A potential role for adiponectin receptor 2 (AdipoR2) in the regulation of alcohol intake Academic Article
- A potential suppressive effect of natural antisense IL-1β RNA on lipopolysaccharide-induced IL-1β expression Academic Article
- A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis Academic Article
- A proapoptotic peptide for the treatment of solid tumors Academic Article
- A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale Academic Article
- A putative bacterial ABC transporter circumvents the essentiality of signal peptidase Academic Article
- A quantitative analysis of connexin-specific permeability differences of gap junctions expressed in HeLa transfectants and Xenopus oocytes Academic Article
- A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions Academic Article
- A rabbit antiserum detects a vh j558 subgroup marker highly expressed among anti-alprenolol antibodies Academic Article
- A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation Academic Article
- A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists Academic Article
- A rationally designed agonist antibody fragment that functionally mimics thrombopoietin Academic Article
- A receptor-induced by lymphocyte-activation (ILA) - a new member of the human nerve-growth-factor tumor-necrosis-factor receptor family Academic Article
- A recombinant antibody interleukin-2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice Academic Article
- A recombinant human enzyme for enhanced interstitial transport of therapeutics Academic Article
- A recombinant minigene vaccine containing a nonameric cytotoxic-t-lymphocyte epitope confers limited protection against listeria monocytogenes infection Academic Article
- A recurrent idiotype on monoclonal anti-human ia antibodies Academic Article
- A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes Academic Article
- A regenerative approach to the treatment of multiple sclerosis Academic Article
- A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes Academic Article
- A remarkable series of vinblastine analogues displaying enhanced activity and an unprecedented tubulin binding steric tolerance: C20' urea derivatives Academic Article
- A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. Possible involvement of TNF in hemolytic uremic syndrome Academic Article
- A requirement for two cell types for antibody formation in vitro Academic Article
- A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors Academic Article
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- Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy Academic Article
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- Long-term monitoring of circadian rhythms in c-fos gene expression from suprachiasmatic nucleus cultures Academic Article
- Long-term persistence and reactivation of t cell memory in the lung of mice infected with respiratory syncytial virus Academic Article
- Long-term phorbol ester treatment down-regulates the beta(3)-adrenergic receptor in 3t3-f442a adipocytes Academic Article
- Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions Academic Article
- Long-term xenogeneic chimeras - full differentiation of rat t-cells and b-cells in scid mice Academic Article
- Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract Academic Article
- Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation Academic Article
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- Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope Academic Article
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- Loss of histaminergic modulation of thermoregulation and energy homeostasis in obese mice Academic Article
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- Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human β-amyloid precursor protein Academic Article
- Loss of nicotine-induced behavioral sensitization in mu-opioid receptor knockout mice Academic Article
- Loss of p53 compensates for alpha(v)-integrin function in retinal neovascularization Academic Article
- Loss of retinal cadherin facilitates mammary tumor progression and metastasis Academic Article
- Loss of sex discrimination and male-male aggression in mice deficient for trp2 Academic Article
- Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome Academic Article
- Loss of spinal substance P pain transmission under the condition of LPA1 receptor-mediated neuropathic pain Academic Article