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STAT3 Transcription Factor

Concept
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  • A functional genomics approach to the mode of action of apratoxin A  Academic Article
  • A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis  Academic Article
  • Adipocytes contribute to the growth and progression of multiple myeloma: Unraveling obesity related differences in adipocyte signaling  Academic Article
  • Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway  Academic Article
  • Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6  Academic Article
  • Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy  Academic Article
  • Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression  Academic Article
  • Essential role of Stat3 in PI3K-induced oncogenic transformation  Academic Article
  • Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours  Academic Article
  • Functional STAT 1 and 3 signaling by the leptin receptor (OB-R): reduced expression of the rat fatty leptin receptor in transfected cells  Academic Article
  • HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria  Academic Article
  • Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation  Academic Article
  • IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis  Academic Article
  • Identification and characterization of small-molecule inducers of fetal hemoglobin  Academic Article
  • Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK  Academic Article
  • Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging  Academic Article
  • Interleukin 18 activates MAPKs and STAT3 but not NF-kappa B in hippocampal HT-22 cells  Academic Article
  • Leptin receptor- and stat3-immunoreactivities in hypocretin/orexin neurones of the lateral hypothalamus  Academic Article
  • Oncostatin M binds to extracellular matrix in a bioactive conformation: Implications for inflammation and metastasis  Academic Article
  • PI3K and STAT3: A new alliance  Academic Article
  • Regulation of STAT protein synthesis by c-Cbl  Academic Article
  • Sequence-selective carbohydrate DNA interaction: Dimeric and monomeric forms of the calicheamicin oligosaccharide interfere with transcription factor function  Academic Article
  • Serum leptin activity in obese and lean patients  Academic Article
  • Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas  Academic Article
  • Splenic and peritoneal B-1 cells differ in terms of transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells  Academic Article
  • Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth  Academic Article
  • Targeted therapeutic remodeling of the tumor microenvironment improves an her-2 DNA vaccine and prevents recurrence in a murine breast cancer model  Academic Article
  • The biology of metastasis to a sanctuary site  Academic Article
  • The il-10r1 s138g loss-of-function allele and ulcerative colitis  Academic Article
  • The lipopolysaccharide-binding protein is a secretory class 1 acute-phase protein whose gene is transcriptionally activated by aprf/stat-3 and other cytokine-inducible nuclear proteins  Academic Article
  • The transient and constitutive inflammatory signaling in tumorigenesis  Academic Article
  • The tyrosine kinase inhibitor gefitinib restricts mycobacterium tuberculosis growth through increased lysosomal biogenesis and modulation of cytokine signaling  Academic Article
  • Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine egfr/stat3/sox-2 signaling pathway  Academic Article

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