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Indoleamine-Pyrrole 2,3,-Dioxygenase

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  • Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis  Academic Article
  • Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model  Academic Article
  • Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans  Academic Article
  • Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors  Academic Article
  • Identifying potential regulators of infantile hemangioma progression through large-scale expression analysis: a possible role for the immune system and indoleamine 2,3 dioxygenase (IDO) during involution  Academic Article
  • Indoleamine 2,3-dioxygenase expression in trans-planted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes  Academic Article
  • Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains  Academic Article
  • Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity  Academic Article
  • Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models  Academic Article

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