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  • 2-Aminobenzimidazoles as potent Aurora kinase inhibitors  Academic Article
  • 68Ga-PSMA-11 PET imaging of response to androgen receptor inhibition: first human experience  Academic Article
  • A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells  Academic Article
  • A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy  Academic Article
  • A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β  Academic Article
  • A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles  Academic Article
  • A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay  Academic Article
  • A cross-species analysis in pancreatic neuroendocrine tumors reveals molecular subtypes with distinctive clinical, metastatic, developmental, and metabolic characteristics  Academic Article
  • A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling  Academic Article
  • A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response  Academic Article
  • A dual color immunohistochemistry assay for measurement of cereblon in multiple myeloma patient samples  Academic Article
  • A fluopol-ABPP HTS assay to identify PAD inhibitors  Academic Article
  • A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding  Academic Article
  • A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly  Academic Article
  • A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes  Academic Article
  • A genetically encoded multifunctional TRAIL trimer facilitates cell-specific targeting and tumor cell killing  Academic Article
  • A genomic screen identifies TYRO3 as a MITF regulator in melanoma  Academic Article
  • A global map of lipid-binding proteins and their ligandability in cells  Academic Article
  • A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters  Academic Article
  • A large noncoding rna is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas  Academic Article
  • A lentiviral vector allowing physiologically regulated membrane-anchored and secreted antibody expression depending on B-cell maturation status  Academic Article
  • A monoclonal antibody to ADAM17 inhibits tumor growth by inhibiting EGFR and non-EGFR-Mediated Pathways  Academic Article
  • A multifunctional bispecific antibody protects against Pseudomonas aeruginosa  Academic Article
  • A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis  Academic Article
  • A novel DNA vaccine encoding pdgfr beta suppresses growth and dissemination of murine colon, lung and breast carcinoma  Academic Article
  • A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target  Academic Article
  • A novel achiral seco-amino-cyclopropylindoline (CI) analog of CC-1065 and the duocarmycins: design, synthesis and biological studies  Academic Article
  • A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells  Academic Article
  • A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties  Academic Article
  • A novel estrogen receptor α-associated protein alters receptor-deoxyribonucleic acid interactions and represses receptor-mediated transcription  Academic Article
  • A novel high-affinity human monoclonal antibody to mesothelin  Academic Article
  • A novel mode of intervention with serine protease activity: targeting zymogen activation  Academic Article
  • A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action  Academic Article
  • A novel, unusually efficacious duocarmycin carbamate prodrug that releases no residual byproduct  Academic Article
  • A peptide that antagonizes tcr-mediated reactions with both syngeneic and allogeneic agonists: Functional and structural aspects  Academic Article
  • A phosphoproteomic analysis of the ErbB2 receptor tyrosine kinase signaling pathways  Academic Article
  • A physical sciences network characterization of non-tumorigenic and metastatic cells  Academic Article
  • A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche  Academic Article
  • A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis  Academic Article
  • A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells  Academic Article
  • A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors  Academic Article
  • A second fatty acid amide hydrolase with variable distribution among placental mammals  Academic Article
  • A selective estrogen receptor modulator for the treatment of hot flushes  Academic Article
  • A selective inhibitor Gal-PUGNAc of human lysosomal beta-hexosaminidases modulates levels of the ganglioside GM2 in neuroblastoma cells  Academic Article
  • A short n-terminal sequence of pten controls cytoplasmic localization and is required for suppression of cell growth  Academic Article
  • A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase  Academic Article
  • A small molecule inhibitor of α4 integrin-dependent cell migration  Academic Article
  • A small molecule inhibits deregulated NRF2 transcriptional activity in cancer  Academic Article
  • A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth  Academic Article
  • A small molecule modulates circadian rhythms through phosphorylation of the period protein  Academic Article
  • A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein  Academic Article
  • A small-molecule antagonist of the hedgehog signaling pathway  Academic Article
  • A stapled p53 helix overcomes HDMX-mediated suppression of p53  Academic Article
  • A structure-guided approach to creating covalent FGFR inhibitors  Academic Article
  • A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors  Academic Article
  • A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity  Academic Article
  • A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy  Academic Article
  • A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation  Academic Article
  • A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate  Academic Article
  • A unique class of duocarmycin and CC-1065 analogues subject to reductive activation  Academic Article
  • AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin  Academic Article
  • ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1  Academic Article
  • ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor  Academic Article
  • ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A  Academic Article
  • Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness  Academic Article
  • Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells  Academic Article
  • Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss  Academic Article
  • Absence of CTL responses to early viral antigens facilitates viral persistence  Academic Article
  • Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma  Academic Article
  • Activating transcription factor 4 promotes angiogenesis of breast cancer through enhanced macrophage recruitment  Academic Article
  • Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor vii  Academic Article
  • Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells  Academic Article
  • Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer  Academic Article
  • Activation of tumor cell integrin alpha(v)beta(3) controls angiogenesis and metastatic growth in the brain  Academic Article
  • Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth  Academic Article
  • Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins  Academic Article
  • Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation  Academic Article
  • Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer  Academic Article
  • Activity-based protein profiling of protein arginine methyltransferase 1  Academic Article
  • Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474  Academic Article
  • Adeno-associated virus enhances wild-type and oncolytic adenovirus spread  Academic Article
  • Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response  Academic Article
  • Adipocytes contribute to the growth and progression of multiple myeloma: Unraveling obesity related differences in adipocyte signaling  Academic Article
  • Adjuvant therapy with agonistic antibodies to CD134 (OX40) increases local control after surgical or radiation therapy of cancer in mice  Academic Article
  • Advantages and limitations of particle-mediated transfection (gene gun) in cancer immuno-gene therapy using IL-10, IL-12 or B7-1 in murine tumor models  Academic Article
  • Akt demoted in glioblastoma  Academic Article
  • Akt regulates the subcellular localization of the Rab27a-binding protein JFC1 by phosphorylation  Academic Article
  • Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets  Academic Article
  • Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy  Academic Article
  • Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells  Academic Article
  • Allosteric control of ligand selectivity between estrogen receptors alpha and beta: Implications for other nuclear receptors  Academic Article
  • Allosteric inhibition of hypoxia inducible factor-2 with small molecules  Academic Article
  • Alteration of the bis-tetrahydrofuran core stereochemistries in asimicin can affect the cytotoxicity  Academic Article
  • Altered trafficking of FAS and subsequent resistance to FAS-mediated apoptosis occurs by a wild-type p53 independent mechanism in esophageal adenocarcinoma  Academic Article
  • Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase  Academic Article
  • Alternatively spliced tissue factor promotes breast cancer growth in a beta 1 integrin-dependent manner  Academic Article
  • Alzheimer's Aβ peptides containing an isostructural backbone mutation afford distinct aggregate morphologies but analogous cytotoxicity. Evidence for a common low-abundance toxic structure(s)?  Academic Article
  • An Mtb-human protein-protein interaction map identifies a switch between host antiviral and antibacterial responses  Academic Article
  • An activity-based imaging probe for the integral membrane hydrolase KIAA1363  Academic Article
  • An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth  Academic Article
  • An anti-B cell maturation antigen bispecific antibody for multiple myeloma  Academic Article
  • An efficient chemical approach to bispecific antibodies and antibodies of high valency  Academic Article
  • An endophytic Neurospora sp. from Nothapodytes foetida producing camptothecin  Academic Article
  • An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling  Academic Article
  • An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system  Academic Article
  • An in vivo tagging method reveals that Ras undergoes sustained activation upon transglutaminase-mediated protein serotonylation  Academic Article
  • An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer  Academic Article
  • An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection  Academic Article
  • Analysis of URI nuclear interaction with RPB5 and components of the R2TP/prefoldin-like complex  Academic Article
  • Analysis of cell-cell contact mediated by Ig superfamily cell adhesion molecules  Academic Article
  • Analysis of microRNAs expressions in chondrosarcoma  Academic Article
  • Androgen receptor splice variants determine taxane sensitivity in prostate cancer  Academic Article
  • Androgen receptor upregulation mediates radioresistance after ionizing radiation  Academic Article
  • Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor  Academic Article
  • Annotating STEAP1 regulation in prostate cancer with (89)Zr immuno-PET  Academic Article
  • Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib  Academic Article
  • Anti-lung cancer activity and inhibitory mechanisms of a novel Calothrixin A derivative  Academic Article
  • Anti-proliferative actions of a synthetic REV-ERBα/β agonist in breast cancer cells  Academic Article
  • Anti-tumor and immunomodulatory activity of resveratrol in vitro and its potential for combining with cancer immunotherapy  Academic Article
  • Antibody microarrays utilizing site-specific antibody-oligonucleotide conjugates  Academic Article
  • Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors  Academic Article
  • Anticancer properties of distinct antimalarial drug classes  Academic Article
  • Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor  Academic Article
  • Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency  Academic Article
  • Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis  Academic Article
  • Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978  Academic Article
  • Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase  Academic Article
  • Antitumor effects and mechanisms ofAZD4547on FGFR2-deregulated endometrial cancer cells  Academic Article
  • Apoptotic tumor cells induce il-27 release from human dcs to activate treg cells that express cd69 and attenuate cytotoxicity  Academic Article
  • Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology  Academic Article
  • Apurinic/apyrimidinic endonuclease 1 alters estrogen receptor activity and estrogen-responsive gene expression  Academic Article
  • Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKK epsilon  Academic Article
  • Arresting cancer proliferation by small-molecule gene regulation  Academic Article
  • Arylsulfonamide kcn1 inhibits in vivo glioma growth and interferes with hif signaling by disrupting hif-1 alpha interaction with cofactors p300/cbp  Academic Article
  • Assessing compound binding to the Eg5 motor domain using a thermal shift assay  Academic Article
  • Assessing enzyme activities using stable isotope labeling and mass spectrometry  Academic Article
  • Assessment of therapeutic efficacy of liposomal nanoparticles mediated gene delivery by molecular imaging for cancer therapy  Academic Article
  • Association with the plasma membrane is sufficient for potentiating catalytic activity of regulators of G protein signaling (RGS) proteins of the R7 subfamily  Academic Article
  • Asymmetric synthesis and biological properties of uncialamycin and 26-epi-uncialamycin  Academic Article
  • Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase  Academic Article
  • Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells  Academic Article
  • Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells  Academic Article
  • Autophagy-regulated ROS from xanthine oxidase acts as an early effector for triggering late mitochondria-dependent apoptosis in cathepsin S-targeted tumor cells  Academic Article
  • Avidity of cd1d-ligand-receptor ternary complex contributes to t-helper 1 (th1) polarization and anticancer efficacy  Academic Article
  • Azaxanthene based selective glucocorticoid receptor modulators: design, synthesis, and pharmacological evaluation of (S)-4-(5-(1-((1,3,4-thiadiazol-2-yl)amino)-2-methyl-1-oxopropan-2-yl)-5H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro-N,N-dimethylbenzamide (BMS-776532) and its methylene homologue (BMS-791826)  Academic Article
  • B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention  Academic Article
  • BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction  Academic Article
  • Background gene expression networks significantly enhance drug response prediction by transcriptional profiling  Academic Article
  • Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain  Academic Article
  • Beta-lactam-based approach for the chemical programming of aldolase antibody 38c2  Academic Article
  • Bidirectional transcription directs both transcriptional gene activation and suppression in human cells  Academic Article
  • Bifunctional electrophiles cross-link thioredoxins with redox relay partners in cells  Academic Article
  • Biobanking: an important resource for precision medicine in glioblastoma  Academic Article
  • Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1  Academic Article
  • Biological and structural evaluation of 10R- and 10S-methylthio-DDACTHF reveals a new role for sulfur in inhibition of glycinamide ribonucleotide transformylase  Academic Article
  • Biomimetic total synthesis of gambogin and rate acceleration of pericyclic reactions in aqueous media  Academic Article
  • Biomimetically inspired total synthesis and structure activity relationships of 1-o-methyllateriflorone. 6 pi electrocyclizations in organic synthesis  Academic Article
  • Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils  Academic Article
  • Bipartite functions of the CREB co-activators selectively direct alternative splicing or transcriptional activation  Academic Article
  • Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors  Academic Article
  • Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors  Academic Article
  • Blocking lactate export by inhibiting the Myc target MCT1 disables glycolysis and glutathione synthesis  Academic Article
  • Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation  Academic Article
  • Both scf(cdc4 alpha) and scf(cdc4 gamma) are required for cyclin e turnover in cell lines that do not overexpress cyclin e  Academic Article
  • Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1  Academic Article
  • Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a  Academic Article
  • Breaking the one antibody-one target axiom  Academic Article
  • Breast cancer cell lines grown in vivo: What goes in isn't always the same as what comes out  Academic Article
  • Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis  Academic Article
  • Brusatol overcomes chemoresistance through inhibition of protein translation  Academic Article
  • Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1  Academic Article
  • Bz-423 superoxide signals B cell apoptosis via Mcl-1, Bak, and Bax  Academic Article
  • CBP is a dosage-dependent regulator of nuclear factor-kappa B suppression by the estrogen receptor  Academic Article
  • CD200 expression on tumor cells suppresses antitumor immunity: new approaches to cancer immunotherapy  Academic Article
  • CDC25B mediates rapamycin-induced oncogenic responses in cancer cells  Academic Article
  • CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability  Academic Article
  • CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma  Academic Article
  • CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation  Academic Article
  • CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation  Academic Article
  • CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma  Academic Article
  • CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling  Academic Article
  • Caged [(18)F]FDG glycosylamines for imaging acidic tumor microenvironments using positron emission tomography  Academic Article
  • Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4t1 murine breast cancer model  Academic Article
  • Cancer gene therapy using a novel secretable trimeric trail  Academic Article
  • Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis  Academic Article
  • Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo  Academic Article
  • Cd22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of b cells  Academic Article
  • Cell based screening of inhibitors of transthyretin aggregation  Academic Article
  • Cell growth inhibition and actin cytoskeleton disorganization induced by azaspiracid-1 structure-activity studies  Academic Article
  • Cell penetrating peptide amphiphile integrated liposomal systems for enhanced delivery of anticancer drugs to tumor cells  Academic Article
  • Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation  Academic Article
  • Cell targeting with hybrid Qβ virus-like particles displaying epidermal growth factor  Academic Article
  • Cell, isoform, and environment factors shape gradients and modulate chemotaxis  Academic Article
  • Cell-specific susceptibility to prion strains is a property of the intact cell  Academic Article
  • Cellular cofactors affecting hepatitis C virus infection and replication  Academic Article
  • Ceramide triggers budding of exosome vesicles into multivesicular endosomes  Academic Article
  • Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays  Academic Article
  • Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.  Academic Article
  • Characterization of a hypoxia-response element in the Epo locus of the pufferfish, Takifugu rubripes  Academic Article
  • Characterization of a side population of astrocytoma cells in response to temozolomide  Academic Article
  • Characterization of lassa virus cell entry inhibitors: Determination of the active enantiomer by asymmetric synthesis  Academic Article
  • Characterization of stem cell-like cancer cells in immune-competent mice  Academic Article
  • Characterization of the human protein S gene promoter: a possible role of transcription factors Sp1 and HNF3 in liver  Academic Article
  • Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect  Academic Article
  • Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens  Academic Article
  • Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices  Academic Article
  • Chemical generation of bispecific antibodies  Academic Article
  • Chemical proteomics identifies druggable vulnerabilities in a genetically defined cancer  Academic Article
  • Chemical synthesis and biological evaluation of palmerolide a analogues  Academic Article
  • Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro  Academic Article
  • Chemically programmed bispecific antibody targeting legumain protease and avß3 integrin mediates strong antitumor effects  Academic Article
  • Chemistry and biology of diazonamide A: Second total synthesis and biological investigations  Academic Article
  • Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol  Academic Article
  • Chemoproteomic evaluation of target engagement by the cyclin-dependent kinase 4 and 6 inhibitor palbociclib correlates with cancer cell response  Academic Article
  • Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma  Academic Article
  • Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism  Academic Article
  • Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis  Academic Article
  • Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription  Academic Article
  • Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3  Academic Article
  • Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells  Academic Article
  • Chromosomal instability estimation based on next generation sequencing and single cell genome wide copy number variation analysis  Academic Article
  • Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels  Academic Article
  • Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints  Academic Article
  • Clathrate nanostructures for mass spectrometry  Academic Article
  • Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors  Academic Article
  • Cold stress-induced protein rbm3 binds 60s ribosomal subunits, alters rnicrorna levels, and enhances global protein synthesis  Academic Article
  • Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Academic Article
  • Combination of anti-HER3 antibody MM-121/SAR256212 and cetuximab inhibits tumor growth in preclinical models of head and neck squamous cell carcinoma  Academic Article
  • Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma  Academic Article
  • Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer  Academic Article
  • Comparative analysis of antitumor activity of CD40L, RANKL, and 4-1BBL in vivo following intratumoral administration of viral vectors or transduced dendritic cells  Academic Article
  • Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion  Academic Article
  • Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues  Academic Article
  • Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells  Academic Article
  • Complete replication of hepatitis C virus in cell culture  Academic Article
  • Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures  Academic Article
  • Comprehensive study of sansalvamide a derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines  Academic Article
  • Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells  Academic Article
  • Conditional regulation of the human CYP4X1 and CYP4Z1 genes  Academic Article
  • Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate  Academic Article
  • Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody  Academic Article
  • Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice  Academic Article
  • Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment  Academic Article
  • Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis  Academic Article
  • Coumarins hinged directly on benzimidazoles and their ribofuranosides to inhibit hepatitis C virus  Academic Article
  • Coupling of receptor conformation and ligand orientation determine graded activity  Academic Article
  • Covalent ligand discovery against druggable hotspots targeted by anti-cancer natural products  Academic Article
  • Crystal structure of the human n-myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor  Academic Article
  • Crystal structures of human HSP90 alpha-complexed with dihydroxyphenylpyrazoles  Academic Article
  • Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim  Academic Article
  • Cyclin E deregulation promotes loss of specific genomic regions  Academic Article
  • Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities  Academic Article
  • Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins  Academic Article
  • Cycloheximide and congeners as inhibitors of eukaryotic protein synthesis from endophytic actinomycetes streptomyces sps. Yim56132 and yim56141  Academic Article
  • Cyclophilin and NS5A inhibitors, but not other anti-hepatitis C virus (HCV) agents, preclude HCV-mediated formation of double-membrane-vesicle viral factories  Academic Article
  • Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site  Academic Article
  • Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites  Academic Article
  • Cyclostreptin derivatives specifically target cellular tubulin and further map the paclitaxel site  Academic Article
  • Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived lncap cell line  Academic Article
  • Cytotoxicity of a Ti(IV) compound is independent of serum proteins  Academic Article
  • DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights  Academic Article
  • DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the nkg2d receptor  Academic Article
  • DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells  Academic Article
  • Darwinian evolution of prions in cell culture  Academic Article
  • Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint  Academic Article
  • Deciphering the chromatin landscape induced around DNA double strand breaks  Academic Article
  • Deep interactome profiling of membrane proteins by co-interacting protein identification technology  Academic Article
  • Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function  Academic Article
  • Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist  Academic Article
  • Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death  Academic Article
  • Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors  Academic Article
  • Deregulation of cyclin e in human cells interferes with prereplication complex assembly  Academic Article
  • Derivation of a retinoid x receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-di(1h-indol-3-yl)methyl-4-trifluoromethylbenzene  Academic Article
  • Design and synthesis of Hsp90 inhibitors: Exploring the SAR of Sansalvamide A derivatives  Academic Article
  • Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis  Academic Article
  • Design, synthesis and biological evaluation of artemisinin derivatives containing fluorine atoms as anticancer agents  Academic Article
  • Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors  Academic Article
  • Design, synthesis and structure-activity relationships of novel biarylamine-based Met kinase inhibitors  Academic Article
  • Design, synthesis, and biological activity of substrate competitive SMYD2 inhibitors  Academic Article
  • Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors  Academic Article
  • Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase  Academic Article
  • Design, synthesis, and biological properties of highly potent epothilone b analogues  Academic Article
  • Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of Jumonji domain-containing protein 2 histone demethylase inhibitors  Academic Article
  • Detecting expression of 5T4 in CTCs and tumor samples from NSCLC patients  Academic Article
  • Detection of human α-L-Fucosidase by a quinone methide-generating probe: enhanced activities in response to Helicobacter pylori Infection  Academic Article
  • Detection of low molecular weight derivatives of cyclin e1 is a function of cyclin e1 protein levels in breast cancer  Academic Article
  • Detection of miRNA in live cells by using templated RuII-catalyzed unmasking of a fluorophore  Academic Article
  • Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors  Academic Article
  • Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties  Academic Article
  • Development of non-peptide ligands of growth factor receptor-bound protein 2-SRC homology 2 domain using molecular modeling and NMR spectroscopy  Academic Article
  • Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB  Academic Article
  • Development of trifunctional probes for glycoproteomic analysis  Academic Article
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  • Differential utilization of upstream augs in the beta-secretase mrna suggests that a shunting mechanism regulates translation  Academic Article
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  • Direct interaction between TKS proteins and the N-terminal proline-rich region (PPR) of NoxA1 mediates Nox1-dependent ROS generation  Academic Article
  • Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe  Academic Article
  • Direct targeting of αvβ3 integrin on tumor cells with a monoclonal antibody, Abegrin™  Academic Article
  • Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors  Academic Article
  • Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system  Academic Article
  • Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-m ethyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through structure-based drug design: a high affinity irreversible inhibitor targeting oncogenic EGFR mutants with selectivity over wild-type EGFR  Academic Article
  • Discovery of TAK-960: an orally available small molecule inhibitor of polo-like kinase 1 (PLK1)  Academic Article
  • Discovery of a noncovalent, mutant-selective epidermal growth factor receptor inhibitor  Academic Article
  • Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomain of CBP/EP300  Academic Article
  • Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152)  Academic Article
  • Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase  Academic Article
  • Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer  Academic Article
  • Discovery of a selective irreversible BMX inhibitor for prostate cancer  Academic Article
  • Discovery of aminopiperidine-based Smac mimetics as IAP antagonists  Academic Article
  • Discovery of matrix metalloproteases selective and activated peptide-doxorubicin prodrugs as anti-tumor agents  Academic Article
  • Discovery of novel drugs for promising targets  Academic Article
  • Discovery of potent and selective covalent inhibitors of JNK  Academic Article
  • Discovery of small-molecule nonfluorescent inhibitors of fluorogen-fluorogen activating protein binding pair  Academic Article
  • Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization  Academic Article
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  • Distinct patterns of somatic alterations in a lymphoblastoid and a tumor genome derived from the same individual  Academic Article
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  • Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol  Academic Article
  • EBV-specific CD4+ T cell clones exhibit vigorous allogeneic responses  Academic Article
  • EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation  Academic Article
  • ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia  Academic Article
  • ERG induces taxane resistance in castration-resistant prostate cancer  Academic Article
  • ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect  Academic Article
  • EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells  Academic Article
  • EZH2 is essential for glioblastoma cancer stem cell maintenance  Academic Article
  • Effect of molecular chaperones on aberrant protein oligomers in vitro: super-versus sub-stoichiometric chaperone concentrations  Academic Article
  • Effective inhibition of HBV replication in vivo by anti-HBx short hairpin RNAs  Academic Article
  • Effects of Cu/Zn superoxide dismutase on estrogen responsiveness and oxidative stress in human breast cancer cells  Academic Article
  • Effects of hydroxamate metalloendoprotease inhibitors on botulinum neurotoxin a poisoned mouse neuromuscular junctions  Academic Article
  • Efficacious cyclic N-acyl O-amino phenol duocarmycin prodrugs  Academic Article
  • Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer  Academic Article
  • Efficient preparation of site-specific antibody-drug conjugates using cysteine insertion  Academic Article
  • Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair  Academic Article
  • Elemental isomerism: A boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands  Academic Article
  • Endoglin (cd105) is a target for an oral DNA vaccine against breast cancer  Academic Article
  • Endothelial protein C receptor function in murine and human breast cancer development  Academic Article
  • Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies  Academic Article
  • Engineering of substrate selectivity for tissue factor.Factor viia complex signaling through protease-activated receptor 2  Academic Article
  • Enhanced activity of hu14.18-il2 immunocytokine against murine nxs2 neuroblastoma when combined with interleukin 2 therapy  Academic Article
  • Enzyme inhibitor discovery by activity-based protein profiling  Academic Article
  • Epothilones: From discovery to clinical trials  Academic Article
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  • Essential role of Stat3 in PI3K-induced oncogenic transformation  Academic Article
  • Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms  Academic Article
  • Estrogen induces lung metastasis through a host compartment-specific response  Academic Article
  • Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription  Academic Article
  • Estrogen-related receptor gamma promotes mesenchymal-to-epithelial transition and suppresses breast tumor growth  Academic Article
  • Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line  Academic Article
  • Evaluation of a reductively activated duocarmycin prodrug against murine and human solid cancers  Academic Article
  • Evaluation of artemisinins for the treatment of acute myeloid leukemia  Academic Article
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  • Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer  Academic Article
  • Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS  Academic Article
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  • Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors  Academic Article
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  • Expression of a soluble transforming growth factor-beta (TGF beta) receptor reduces tumorigenicity by regulating natural killer (NK) cell activity against 9L gliosarcoma in vivo  Academic Article
  • Expression of c-Fes protein isoforms correlates with differentiation in myeloid leukemias  Academic Article
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  • Fc-small molecule antibody mimetics  Academic Article
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  • Forced expression of mir-143 represses erk5/c-myc and p68/p72 signaling in concert with mir-145 in gut tumors of apc(min) mice  Academic Article
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  • Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays  Academic Article
  • Foxp3 expression is required for the induction of therapeutic tissue tolerance  Academic Article
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  • Fra-1 protooncogene regulates il-6 expression in macrophages and promotes the generation of m2d macrophages  Academic Article
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  • Fully functionalized small-molecule probes for integrated phenotypic screening and target identification  Academic Article
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  • Functional role of asparaginyl endopeptidase ubiquitination by TRAF6 in tumor invasion and metastasis  Academic Article
  • GPR92 as a new G12/13 and Gq-coupled lysophosphatidic acid receptor that increases cAMP: LPA5  Academic Article
  • Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests  Academic Article
  • Ganoderma lucidum polysaccharides in human monocytic leukemia cells: From gene expression to network construction  Academic Article
  • Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development  Academic Article
  • Generation and validation of structurally defined antibody-siRNA conjugates  Academic Article
  • Generation of quorum quenching antibodies  Academic Article
  • Genome-wide analysis reveals padi4 cooperates with elk-1 to activate c-fos expression in breast cancer cells  Academic Article
  • Genome-wide gain-of-function screen identifies novel regulators of pluripotency  Academic Article
  • Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers  Academic Article
  • Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis  Academic Article
  • Glioma-induced remodeling of the neurovascular unit  Academic Article
  • Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms  Academic Article
  • Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway  Academic Article
  • Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer  Academic Article
  • Glutathione transferase-M2-2 secreted from glioblastoma cell protects SH-SY5Y cells from aminochrome neurotoxicity  Academic Article
  • Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis  Academic Article
  • Growth and differentiation of prechondrogenic cells on bioactive self-assembled peptide nanofibers  Academic Article
  • Guiding plant virus particles to integrin-displaying cells  Academic Article
  • HCV core residues critical for infectivity are also involved in core-NS5A complex formation  Academic Article
  • HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas  Academic Article
  • Ha-pseudotyped retroviral vectors for influenza antagonist screening  Academic Article
  • Hard top soft bottom microfluidic devices for cell culture and chemical analysis  Academic Article
  • Harnessing cyanine reactivity for optical imaging and drug delivery  Academic Article
  • Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress  Academic Article
  • Hepatocyte nuclear factor-4-independent synthesis of coagulation factor vii in breast cancer cells and its inhibition by targeting selective histone acetyltransferases  Academic Article
  • Heregulin-ErbB3-driven tumor growth persists in PI3 kinase mutant cancer cells  Academic Article
  • Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells  Academic Article
  • Hiers: Hierarchical scaffold clustering using topological chemical graphs  Academic Article
  • Hif2 alpha-sp1 interaction mediates a deacetylation-dependent fvii-gene activation under hypoxic conditions in ovarian cancer cells  Academic Article
  • High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array  Academic Article
  • High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase  Academic Article
  • High-yield isolation of extracellular vesicles using aqueous two-phase system  Academic Article
  • Histone arg modifications and p53 regulate the expression of okl38, a mediator of apoptosis  Academic Article
  • Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability  Academic Article
  • Histone deacetylase inhibitors enhance lexaturnurnab-induced apoptosis via a p21(cip1)-dependent decrease in survivin levels  Academic Article
  • Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication  Academic Article
  • Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4  Academic Article
  • Hrr25/CK1 delta-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth  Academic Article
  • Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus  Academic Article
  • Human embryonic stem cells have a unique epigenetic signature  Academic Article
  • Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis  Academic Article
  • Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease  Academic Article
  • Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors  Academic Article
  • Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker  Academic Article
  • Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and par-2-mediated heparin-binding egf signaling in endothelial cells  Academic Article
  • Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells  Academic Article
  • IFITM proteins restrict antibody-dependent enhancement of dengue virus infection  Academic Article
  • IGF1R-and ROR1-specific CAR T cells as a potential therapy for high risk sarcomas  Academic Article
  • IMD-0354 targets breast cancer stem cells: a novel approach for an adjuvant to chemotherapy to prevent multidrug resistance in a murine model  Academic Article
  • INPP4B suppresses prostate cancer cell invasion  Academic Article
  • Identification and characterization of a novel estrogenic ligand actinopolymorphol a  Academic Article
  • Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins  Academic Article
  • Identification and characterization of small-molecule inducers of fetal hemoglobin  Academic Article
  • Identification and characterization of the first small molecule inhibitor of MDMX  Academic Article
  • Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing  Academic Article
  • Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1)  Academic Article
  • Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
  • Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion  Academic Article
  • Identification of a novel Mcl-1 protein binding motif  Academic Article
  • Identification of a novel drug lead that inhibits HCV infection and cell-to-cell transmission by targeting the HCV E2 glycoprotein  Academic Article
  • Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway  Academic Article
  • Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers  Academic Article
  • Identification of alk as a major familial neuroblastoma predisposition gene  Academic Article
  • Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)  Academic Article
  • Identification of an EGFRvIII-JNK2-HGF/c-Met-signaling axis required for intercellular crosstalk and glioblastoma multiforme cell invasion  Academic Article
  • Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling  Academic Article
  • Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases  Academic Article
  • Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening  Academic Article
  • Identification of kinectin as a novel Behçet's disease autoantigen  Academic Article
  • Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility  Academic Article
  • Identification of novel ROS inducers: quinone derivatives tethered to long hydrocarbon chains  Academic Article
  • Identification of novel binding elements and gene targets for the homeodomain protein BARX2  Academic Article
  • Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach  Academic Article
  • Identification of small molecule activators of cryptochrome  Academic Article
  • Identification of small-molecule inhibitors of the colorectal cancer oncogene Kruppel-like factor 5 expression by ultrahigh-throughput screening  Academic Article
  • Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells  Academic Article
  • Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1  Academic Article
  • Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling  Academic Article
  • Identification of tumor-associated antigens as diagnostic and predictive biomarkers in cancer  Academic Article
  • IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions  Academic Article
  • Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen  Academic Article
  • Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery  Academic Article
  • Imaging of tumor vascularization using fluorescence molecular tomography to monitor arginine deiminase treatment in melanoma  Academic Article
  • Imaging tumor burden in the brain with 89-Zr-transferrin  Academic Article
  • Immunologic effects of an orally available BRAFV600E inhibitor in BRAF wild-type murine models  Academic Article
  • Impact of substituents in tumor uptake and fluorescence imaging ability of near-infrared cyanine-like dyes  Academic Article
  • Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor  Academic Article
  • Improving the TFold test for differential shotgun proteomics  Academic Article
  • In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis  Academic Article
  • In situ kinase profiling reveals functionally relevant properties of native kinases  Academic Article
  • In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots  Academic Article
  • In vivo brain GPCR signaling elucidated by phosphoproteomics  Academic Article
  • In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated beta1 integrin and induction of FAK/PI3K/Akt motility signaling  Academic Article
  • In vivo efficacy of natural product-inspired irreversible kinase inhibitors  Academic Article
  • In vivo modification of native carrier protein domains  Academic Article
  • In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential  Academic Article
  • In vivo selection for metastasis promoting genes in the mouse  Academic Article
  • In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for icam-1 provides new insights into gene regulation  Academic Article
  • Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies  Academic Article
  • Individually programmable cell stretching microwell arrays actuated by a Braille display  Academic Article
  • Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells  Academic Article
  • Induction of Cullin 7 by DNA damage attenuates p53 function  Academic Article
  • Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer  Academic Article
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  • Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells  Academic Article
  • Inhibition of acetyl-CoA carboxylase 1 (ACC1) and 2 (ACC2) reduces proliferation and de novo lipogenesis of EGFRvIII human glioblastoma cells  Academic Article
  • Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance  Academic Article
  • Inhibition of cancer cell proliferation by designed peptide amphiphiles  Academic Article
  • Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms  Academic Article
  • Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1  Academic Article
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  • Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells  Academic Article
  • Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice  Academic Article
  • Integrin alpha beta 1, alpha(v)beta, alpha(6)beta effectors p130Cas, Src and talin regulate carcinoma invasion and chemoresistance  Academic Article
  • Interaction of epothilone analogs with the paclitaxel binding site: Relationship between binding affinity, microtubule stabilization, and cytotoxicity  Academic Article
  • Interaction of estrogen receptor alpha with proliferating cell nuclear antigen  Academic Article
  • Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor alpha alters estrogen-responsive gene expression  Academic Article
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  • Interferon-γ production by peripheral lymphocytes predicts survival of tumor-bearing mice receiving dual PD-1/CTLA-4 blockade  Academic Article
  • Interleukin-6-induced plasminogen gene expression in murine hepatocytes is mediated by transcription factor CCAAT/enhancer binding protein beta (C/EBP beta)  Academic Article
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  • Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation  Academic Article
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  • Intratumoral hu14.18-il-2 (ic) induces local and systemic antitumor effects that involve both activated t and nk cells as well as enhanced ic retention  Academic Article
  • Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the Hu14.18 antibody increases intratumoral CD8+T and NK cells and improves survival  Academic Article
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  • Isolation of human prostate cancer cell reactive antibodies using phage display technology  Academic Article
  • Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor alpha  Academic Article
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  • Lkb1 and sad kinases define a pathway required for the polarization of cortical neurons  Academic Article
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  • Lysosomal glycosphingolipid recognition by NKT cells  Academic Article
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  • MDM4 is a key therapeutic target in cutaneous melanoma  Academic Article
  • ML264, A novel small-molecule compound that potently inhibits growth of colorectal cancer  Academic Article
  • MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM  Academic Article
  • MOR209/ES414, a novel bispecific antibody targeting PSMA for the treatment of metastatic castration-resistant prostate cancer  Academic Article
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  • Metabolism of oxidized linoleic acid by glutathione transferases: Peroxidase activity toward 13-hydroperoxyoctadecadienoic acid  Academic Article
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  • Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen chlamydia trachomatis by targeting peptide deformylase of the bacterium  Academic Article
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  • MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer  Academic Article
  • MicroRNA-140 acts as a liver tumor suppressor by controlling NF-kappaB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression  Academic Article
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  • MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension  Academic Article
  • Microfluidic control of cell pairing and fusion  Academic Article
  • Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells  Academic Article
  • Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells  Academic Article
  • Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis  Academic Article
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  • Targeting heat shock proteins on cancer cells: Selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand  Academic Article
  • Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes  Academic Article
  • Targeting malignant B cells with an immunotoxin against ROR1  Academic Article
  • Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA  Academic Article
  • Targeting ornithine decarboxylase impairs development of mycn-amplified neuroblastoma  Academic Article
  • Targeting renal cell carcinoma with a HIF-2 antagonist  Academic Article
  • Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening  Academic Article
  • Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells  Academic Article
  • Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B  Academic Article
  • Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism  Academic Article
  • Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the raf-1 pathway  Academic Article
  • Tcr binding kinetics measured with mhc class i tetramers reveal a positive selecting peptide with relatively high affinity for tcr  Academic Article
  • Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression  Academic Article
  • The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted  Academic Article
  • The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor  Academic Article
  • The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity  Academic Article
  • The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain  Academic Article
  • The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus  Academic Article
  • The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment  Academic Article
  • The NS5A protein of hepatitis C virus is a zinc metalloprotein  Academic Article
  • The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells  Academic Article
  • The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination  Academic Article
  • The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase  Academic Article
  • The anti-tumor effect of resveratrol alone or in combination with immunotherapy in a neuroblastoma model  Academic Article
  • The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death  Academic Article
  • The antitumor effects of adenoviral-mediated, intratumoral delivery of interleukin 23 require endogenous IL-12  Academic Article
  • The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry  Academic Article
  • The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus  Academic Article
  • The benzenesulfoamide T0901317 (N-(2,2,2-trifluoroethyl)-N-(4-( 2,2,2-trifluoro-1-hydroxy-1-(trifluorome thyl)ethyl phenyl -benzenesulfonamide is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist  Academic Article
  • The butterfly effect in cancer: A single base mutation can remodel the cell  Academic Article
  • The cancer drug dasatinib increases PGC-1α in adipose tissue but has adverse effects on glucose tolerance in obese mice  Academic Article
  • The combination of i-leader truncation and gemcitabine improves oncolytic adenovirus efficacy in an immunocompetent model  Academic Article
  • The cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection  Academic Article
  • The death effector domains of caspase-8 induce terminal differentiation  Academic Article
  • The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells  Academic Article
  • The deoxyribonucleic acid repair protein flap endonuclease-1 modulates estrogen-responsive gene expression  Academic Article
  • The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of Type 2 diabetes mellitus  Academic Article
  • The development of n-alpha-(2-carboxyl)benzoyl-n(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-f-amidine) and n-alpha-(2-carboxyl)benzoyl-n(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-cl-amidine) as second generation protein arginine deiminase (pad) inhibitors  Academic Article
  • The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines  Academic Article
  • The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways  Academic Article
  • The familial parkinson's disease gene dj-1 (park7) is expressed in red cells and plays a role in protection against oxidative damage  Academic Article
  • The induction of microrna-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest  Academic Article
  • The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin cd151  Academic Article
  • The iroquois homeobox gene 5 is regulated by 1,25-dihydroxyvitamin D(3) in human prostate cancer and regulates apoptosis and the cell cycle in LNCaP prostate cancer cells  Academic Article
  • The legumain protease-activated auristatin prodrugs suppress tumor growth and metastasis without toxicity  Academic Article
  • The leptin receptor system of human platelets  Academic Article
  • The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1  Academic Article
  • The membrane-anchored serine protease, tmprss2, activates par-2 in prostate cancer cells  Academic Article
  • The neuroprotective effects of lonicera japonica thunb. Against hydrogen peroxide-induced apoptosis via phosphorylation of mapks and pi3k/akt in sh-sysy cells  Academic Article
  • The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity  Academic Article
  • The nuclear receptor lxr is a glucose sensor  Academic Article
  • The plasma membrane Na+/Ca2+ exchanger is cleaved by distinct protease families in neuronal cell death  Academic Article
  • The primacy of beta1 integrin activation in the metastatic cascade  Academic Article
  • The protein acetyltransferase ard1: A novel cancer drug target?  Academic Article
  • The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells  Academic Article
  • The rational design of selective benzoxazepin inhibitors of the α-isoform of phosphoinositide 3-kinase culminating in the identification of (S)-2-((2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo f imidazo 1,2-d 1,4 oxazepin-9-yl)oxy)propanamide (GDC-0326)  Academic Article
  • The role of ARF1 and rab GTPases in polarization of the Golgi stack  Academic Article
  • The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations  Academic Article
  • The role of RPA2 phosphorylation in homologous recombination in response to replication arrest  Academic Article
  • The role of acetaldehyde in mediating effects of alcohol on expression of endogenous opioid system genes in a neuroblastoma cell line  Academic Article
  • The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression  Academic Article
  • The role of stat, ap-1, e-box and tieg motifs in the regulation of hepcidin by il-6 and bmp-9: Lessons from human hamp and murine hamp1 and hamp2 gene promoters  Academic Article
  • The serine protease tmprss6 is required to sense iron deficiency  Academic Article
  • The tick-derived inhibitor ixolaris prevents tissue factor signaling on tumor cells  Academic Article
  • The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPalpha during granulocytic differentiation but repressed by PML-RARalpha in APL  Academic Article
  • Thioredoxin and thioredoxin reductase influence estrogen receptor alpha-mediated gene expression in human breast cancer cells  Academic Article
  • Thyroxine-binding antibodies inhibit T cell recognition of a pathogenic thyroglobulin epitope  Academic Article
  • Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interieukin-8  Academic Article
  • Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture  Academic Article
  • Tissue factor prothrombotic activity is regulated by integrin-arf6 trafficking  Academic Article
  • Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment  Academic Article
  • Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds  Academic Article
  • Total synthesis and biological evaluation of (-)apicularen a and analogues thereof  Academic Article
  • Total synthesis and biological evaluation of cortistatins a and j and analogues thereof  Academic Article
  • Total synthesis and biological evaluation of halipeptins a and d and analogues  Academic Article
  • Total synthesis and biological evaluation of monorhizopodin and 16-epi-monorhizopodin  Academic Article
  • Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs  Academic Article
  • Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives  Academic Article
  • Total synthesis and evaluation of iso-duocarmycin SA and iso-yatakemycin  Academic Article
  • Total synthesis of apoptolidin: Completion of the synthesis and analogue synthesis and evaluation  Academic Article
  • Total synthesis of englerin a  Academic Article
  • Total synthesis of vinblastine, related natural products, and key analogues and development of inspired methodology suitable for the systematic study of their structure-function properties  Academic Article
  • Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues  Academic Article
  • Transcription control by the ENL YEATS domain in acute leukaemia  Academic Article
  • Transcriptional profiling identifies the signaling axes of IGF and transforming growth factor-β as involved in the pathogenesis of osteosarcoma  Academic Article
  • Transcriptional regulation of MIR29B by PU.1 (SPI1) and MYC during neutrophil differentiation of acute promyelocytic leukaemia cells  Academic Article
  • Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line  Academic Article
  • Transfer of a prion strain to different hosts leads to emergence of strain variants  Academic Article
  • Transferrin-mediated targeting of bacteriophage hk97 nanoparticles into tumor cells  Academic Article
  • Transportin regulates nuclear import of CD44  Academic Article
  • Triomics analysis of imatinib-treated myeloma cells connects kinase inhibition to RNA processing and decreased lipid biosynthesis  Academic Article
  • Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state  Academic Article
  • Tropomodulins are negative regulators of neurite outgrowth  Academic Article
  • Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination  Academic Article
  • Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia  Academic Article
  • Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition  Academic Article
  • Tumor endothelial cell tube formation model for determining anti-angiogenic activity of a tRNA synthetase cytokine  Academic Article
  • Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine egfr/stat3/sox-2 signaling pathway  Academic Article
  • Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation  Academic Article
  • Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis  Academic Article
  • Tuning the mechanical and bioresponsive properties of peptide-amphiphile nanofiber networks  Academic Article
  • Twist1 induces CCL2 and recruits macrophages to promote angiogenesis  Academic Article
  • Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements  Academic Article
  • USP15 negatively regulates Nrf2 through deubiquitination of Keap1  Academic Article
  • USP7 small-molecule inhibitors interfere with ubiquitin binding  Academic Article
  • Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2  Academic Article
  • Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination  Academic Article
  • Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia  Academic Article
  • Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents  Academic Article
  • Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling  Academic Article
  • Using proteomic approach to identify tumor-associated antigens as markers in hepatocellular carcinoma  Academic Article
  • VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses  Academic Article
  • Vector prime/protein boost vaccine that overcomes defects acquired during aging and cancer  Academic Article
  • Ventromorphins: a new class of small molecule activators of the canonical BMP signaling pathway  Academic Article
  • Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery  Academic Article
  • Versatile strategy for controlling the specificity and activity of engineered T cells  Academic Article
  • Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein  Academic Article
  • Vinblastine 20 ' amides: synthetic analogues that maintain or improve potency and simultaneously overcome Pgp-derived efflux and resistance  Academic Article
  • WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility  Academic Article
  • When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as CCR2 antagonists  Academic Article
  • Withaferin A analogs that target the AAA plus chaperone p97  Academic Article
  • XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck  Academic Article
  • Yy1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription  Academic Article
  • ZNRD1 (zinc ribbon domain-containing 1) is a host cellular factor that influences HIV-1 replication and disease progression  Academic Article
  • Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology  Academic Article
  • iRGD tumor-penetrating peptide-modified oncolytic adenovirus shows enhanced tumor transduction, intratumoral dissemination and antitumor efficacy  Academic Article
  • lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs  Academic Article
  • p53 nongenotoxic activation and mTORC1 inhibition lead to effective combination for neuroblastoma therapy  Academic Article
  • p53-mediated apoptosis requires inositol hexakisphosphate kinase-2  Academic Article
  • p97 negatively regulates NRF2 by extracting ubiquitylated NRF2 from the KEAP1-CUL3 E3 complex  Academic Article
  • α-MSH regulates intergenic splicing of MC1R and TUBB3 in human melanocytes  Academic Article
  • β-Peptides with improved affinity for hDM2 and hDMX  Academic Article

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