subject area of
- A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPAR gamma partial agonists Academic Article
- A dominant-negative peroxisome proliferator-activated receptor gamma (ppar gamma) mutant is a constitutive repressor and inhibits ppar gamma-mediated adipogenesis Academic Article
- A novel method for analysis of nuclear receptor function at natural promoters: Peroxisome proliferator-activated receptor gamma agonist actions on ap2 gene expression detected using branched DNA messenger rna quantitation Academic Article
- Activators of the nuclear receptor ppar gamma enhance colon polyp formation Academic Article
- Analysis of human cytochrome P4502C8 substrate specificity using a substrate pharmacophore and site-directed mutants Academic Article
- Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR gamma by Cdk5 Academic Article
- Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation Academic Article
- Cancer-derived mutations in the regulatory subunit p85α of phosphoinositide 3-kinase function through the catalytic subunit p110α Academic Article
- Determinants of cytochrome P4502C8 substrate binding - structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid Academic Article
- Discovery, synthesis and sar analysis of novel selective small molecule s1p(4)-r agonists based on a (2z,5z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-o ne chemotype Academic Article
- Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice Academic Article
- Effect of thiazolidinediones on expression of ucp2 and adipocyte markers in human paz6 adipocytes Academic Article
- High-throughput kinase profiling: A more efficient approach toward the discovery of new kinase inhibitors Academic Article
- Hydrogen/deuterium-exchange (H/D-Ex) of PPAR gamma LBD in the presence of various modulators Academic Article
- Induction of plasminogen activator inhibitor 1 gene expression in adipocytes by thiazolidinediones Academic Article
- Interventional cardiology - peroxisome proliferator-activated receptor gamma agonists for the prevention of adverse events following percutaneous coronary revascularization - results of the ppar study Academic Article
- L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding Academic Article
- Ligand and receptor dynamics contribute to the mechanism of graded PPAR gamma agonism Academic Article
- Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma 2 Academic Article
- Nuclear receptors have distinct affinities for coactivators: characterization by fluorescence resonance energy transfer Academic Article
- PPARG post-translational modifications regulate bone formation and bone resorption Academic Article
- Percutaneous coronary intervention in diabetic patients with non-st-segment elevation acute coronary syndromes Academic Article
- Peroxisome proliferator-activated receptor (ppar) gamma coactivator-1 recruitment regulates ppar subtype specificity Academic Article
- Peroxisome proliferator-activated receptor gamma down-regulates receptor for advanced glycation end products and inhibits smooth muscle cell proliferation in a diabetic and nondiabetic rat carotid artery injury model Academic Article
- Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes Academic Article
- Ppar gamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes Academic Article
- Regulation of adipogenesis by natural and synthetic REV-ERB ligands Academic Article
- Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor gamma coactivator-1 alpha Academic Article
- Targeting orphan nuclear receptors for treatment of metabolic diseases and autoimmunity Academic Article