subject area of
- Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1 Academic Article
- Activated protein C analog promotes neurogenesis and improves neurological outcome after focal ischemic stroke in mice via protease activated receptor 1 Academic Article
- Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3 Academic Article
- Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1 Academic Article
- Activated protein C variants with normal cytoprotective but reduced anticoagulant activity Academic Article
- Activated protein c blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective Academic Article
- Activated protein c signals through the thrombin receptor par1 in endothelial cells Academic Article
- Activated protein c-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin Academic Article
- Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor vii Academic Article
- Activation of endothelial cell protease activated receptor 1 by the protein c pathway Academic Article
- Apolipoprotein E receptor 2 mediates activated protein C-induced endothelial Akt activation and endothelial barrier stabilization Academic Article
- Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46 Academic Article
- Cell painting with an engineered EPCR to augment the protein C system Academic Article
- Coagulation factor xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein c receptor Academic Article
- Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition Academic Article
- Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes Academic Article
- Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation Academic Article
- Endothelial barrier protection by activated protein c through par1-dependent sphingosine 1-phosphate receptor-1 crossactivation Academic Article
- Factor xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1 Academic Article
- Failure to validate association of gene polymorphisms in EPCR, PAR-1, FSAP and protein S Tokushima with venous thromboembolism among Californians of European ancestry Academic Article
- G protein-coupled receptor Ca2+-linked mlitochondrial reactive oxygen species are essential for endothelial/leukocyte adherence Academic Article
- Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1 Academic Article
- Inflammation, obesity, and thrombosis Academic Article
- Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor Academic Article
- Inhibition of tissue factor signaling suppresses tumor growth Academic Article
- Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway Academic Article
- Molecular regulation of blood clotting in tumor biology Academic Article
- Neutrophil activation by the tissue factor/factor viia/par2 axis mediates fetal death in a mouse model of anti phospholipid syndrome Academic Article
- Noncanonical PAR3 activation by factor Xa identifies a novel pathway for Tie2 activation and stabilization of vascular integrity Academic Article
- Orchestration of coagulation protease signaling by tissue factor Academic Article
- PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells Academic Article
- Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1) Academic Article
- Plasminogen inhibits TNF alpha-induced apoptosis in monocytes Academic Article
- Protease-activated receptor (par) 2, but not par1, signaling promotes the development of mammary adenocarcinoma in polyoma middle t mice Academic Article
- Protease-activated receptor (par)1 alters bioelectric properties of distal lung epithelia without compromising barrier function Academic Article
- Protease-activated receptor-1 cleaved at r46 mediates cytoprotective effects Academic Article
- Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity Academic Article
- Protease-activated receptor-1 signaling by activated protein c in cytokine-perturbed endothelial cells is distinct from thrombin signaling Academic Article
- Protease-activated receptors (par1 and par2) contribute to tumor cell motility and metastasis Academic Article
- Protease-activated receptors-1 and-2 can mediate endothelial barrier protection: Role in factor xa signaling Academic Article
- Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1 Academic Article
- Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant Academic Article
- Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor Academic Article
- Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis Academic Article
- The cytoprotective protein C pathway Academic Article
- The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors Academic Article
- Thrombin affects eosinophil migration via protease-activated receptor-1 Academic Article
- Tissue factor and par1 promote microbiota-induced intestinal vascular remodelling Academic Article
- Tissue factor and protease-activated receptor signaling in cancer Academic Article
- Tissue factor-dependent signaling in tumor biology Academic Article
- Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination Academic Article
- Unique pathway of thrombin-induced platelet aggregation mediated by glycoprotein Ib Academic Article