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Genomic Instability

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  • A Saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability  Academic Article
  • A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers  Academic Article
  • A novel histone deacetylase complex in the control of transcription and genome stability  Academic Article
  • A semi-synthetic organism with an expanded genetic alphabet  Academic Article
  • Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins  Academic Article
  • Bioinformatic identification of genes suppressing genome instability  Academic Article
  • CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability  Academic Article
  • CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis  Academic Article
  • Cancer: Aneuploidy drives a mutator phenotype in cancer  Academic Article
  • Cdc73 suppresses genome instability by mediating telomere homeostasis  Academic Article
  • Chromosomal instability estimation based on next generation sequencing and single cell genome wide copy number variation analysis  Academic Article
  • Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growth  Academic Article
  • Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures  Academic Article
  • Cyclin E deregulation promotes loss of specific genomic regions  Academic Article
  • Determination of gross chromosomal rearrangement rates  Academic Article
  • Development of live-attenuated arenavirus vaccines based on codon deoptimization  Academic Article
  • Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements  Academic Article
  • Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions  Academic Article
  • EEPD1 rescues stressed replication forks and maintains genome stability by promoting end resection and homologous recombination repair  Academic Article
  • ERCC1-XPF endonuclease facilitates DNA double-strand break repair  Academic Article
  • EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart  Academic Article
  • Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming  Academic Article
  • Genome stability roles of sumo-targeted ubiquitin ligases  Academic Article
  • Genomic instability in pluripotent stem cells: implications for clinical applications  Academic Article
  • Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast  Academic Article
  • Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases  Academic Article
  • Increased risk of genetic and epigenetic instability in human embryonic stem cells associated with specific culture conditions  Academic Article
  • Ku stabilizes replication forks in the absence of brc1  Academic Article
  • Mms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombe  Academic Article
  • Molecular mimicry of SUMO promotes DNA repair  Academic Article
  • Mouse models of fanconi anemia  Academic Article
  • Pathways and mechanisms that prevent genome instability in Saccharomyces cerevisiae  Academic Article
  • Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI)  Academic Article
  • Positional stability of single double-strand breaks in mammalian cells  Academic Article
  • Post-replication repair suppresses duplication-mediated genome instability  Academic Article
  • Prevention of DNA re-replication in eukaryotic cells  Academic Article
  • Rad3 decorates critical chromosomal domains with γH2A to protect genome integrity during S-Phase in fission yeast  Academic Article
  • Replication checkpoint kinase Cds1 regulates Mus81 to reserve genome integrity during replication stress  Academic Article
  • Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant  Academic Article
  • SUMO-targeted ubiquitin ligase activity can either suppress or promote genome instability, depending on the nature of the DNA lesion  Academic Article
  • SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability  Academic Article
  • Sumo-targeted ubiquitin ligases in genome stability  Academic Article
  • The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex  Academic Article
  • The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast  Academic Article
  • The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects  Academic Article
  • The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair  Academic Article
  • The maize (Zea mays L.) nucleoside diphosphate kinase1 (ZmNDPK1) gene encodes a human NM23-H2 homologue that binds and stabilizes G-quadruplex DNA  Academic Article
  • The peculiar biology of mouse mesenchymal stromal cells-oxygen is the key  Academic Article
  • The role of RPA2 phosphorylation in homologous recombination in response to replication arrest  Academic Article
  • Therapeutic applications of mesenchymal stem cells: current outlook  Academic Article
  • Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability  Academic Article

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