subject area of
- A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition Academic Article
- A single amino acid change in the binding pocket alters specificity of an anti-integrin antibody AP7.4 as revealed by its crystal structure Academic Article
- Antibody modeling assessment II. Structures and models Academic Article
- Antigen-driven selection of tcr in vivo: Related tcr alpha-chains pair with diverse tcr beta-chains Academic Article
- Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics Academic Article
- Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5 Academic Article
- Construction, affinity maturation, and biological characterization of an anti-tumor-associated glycoprotein-72 humanized antibody Academic Article
- Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections Academic Article
- Cross-neutralization of influenza a viruses mediated by a single antibody loop Academic Article
- Crystal structure determination of anti-DNA Fab A52 Academic Article
- Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1 Academic Article
- Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design Academic Article
- Crystal structure of a shark single-domain antibody v region in complex with lysozyme Academic Article
- Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor Academic Article
- Crystal structure of mouse cd1d bound to the self ligand phosphatidylcholine: A molecular basis for nkt cell activation Academic Article
- Development of a high-throughput screen for protein catalysts: application to the directed evolution of antibody aldolases Academic Article
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Academic Article
- Ectopic B-cell clusters that infiltrate transplanted human kidneys are clonal Academic Article
- Emergence of a type ii collagen-specific helper t cell response Academic Article
- Evolution of antigen-specific t cell receptors in vivo: Preimmune and antigen-driven selection of preferred complementarity-determining region 3 (cdr3) motifs Academic Article
- Fine specificity of tcr complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a cd1-lipid complex Academic Article
- Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing Academic Article
- Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire Academic Article
- Functional antibody CDR3 fusion proteins with enhanced pharmacological properties Academic Article
- Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists Academic Article
- HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage Academic Article
- HTLV-I env protein acts as a major antigen in patients with HTLV-I-associated arthropathy Academic Article
- Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes Academic Article
- Identification and characterization of single chain anti-cocaine catalytic antibodies Academic Article
- Integrin α(IIb)β(3)-specific synthetic human monoclonal antibodies and HCDR3 peptides that potently inhibit platelet aggregation Academic Article
- Malachite green mediates homodimerization of antibody VL domains to form a fluorescent ternary complex with singular symmetric interfaces Academic Article
- Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120 Academic Article
- Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies Academic Article
- Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a beta-linked self-glycolipid Academic Article
- Paucity of V-D-D-J rearrangements and V-H replacement events in lupus prone and nonautoimmune TdT(-/-) and TdT(+/+) mice Academic Article
- Prevention of cell death by antibodies selected from intracellular combinatorial libraries Academic Article
- Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen Academic Article
- Rational design of CXCR4 specific antibodies with elongated CDRs Academic Article
- Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth Academic Article
- Relationship between antibody 2f5 neutralization of hiv-1 and hydrophobicity of its heavy chain third complementarity-determining region Academic Article
- Reshaping antibody diversity Academic Article
- Structural basis for amide hydrolysis catalyzed by the 43C9 antibody Academic Article
- Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Academic Article
- Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2f5 in complex with its gp41 epitope Academic Article
- T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses Academic Article
- Terminal deoxynucleotidyl transferase deficiency decreases autoimmune disease in MRL-Fas(lpr) mice Academic Article
- The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies Academic Article
- The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2f5 Academic Article
- The role of HLA-DQ8 beta 57 polymorphism in the anti-gluten T-cell response in coeliac disease Academic Article
- Tissue-specific expressed antibody variable gene repertoires Academic Article
- Towards the generation of artificial O(6)-alkylguanine-DNA alkyltransferases: in vitro selection of antibodies with reactive cysteine residues Academic Article
- Unusual germline DSP2 gene accounts for all apparent V-D-D-J rearrangements in newborn, but not adult, MRL mice Academic Article