subject area of
- A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia Academic Article
- Activated integrin alpha v beta 3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells Academic Article
- Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage Academic Article
- Activation of matrix metalloproteinase-9 (mmp-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion Academic Article
- Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death Academic Article
- Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases Academic Article
- Anacardic acid inhibits the catalytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 Academic Article
- Angiogenic capacity of M1-and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9 Academic Article
- Angiotensin type 1 receptor block age improves ischemic injury following transient focal cerebral ischemia Academic Article
- Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib Academic Article
- Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes Academic Article
- Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic balloon injury model Academic Article
- Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1 Academic Article
- Cloning of rat 92-kda type iv collagenase and expression of an active recombinant catalytic domain Academic Article
- Differential regulation of cell motility and invasion by fak Academic Article
- EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation Academic Article
- Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis Academic Article
- Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice Academic Article
- Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha(5)beta(1) and alpha(v)beta(5) Academic Article
- Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke Academic Article
- Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis Academic Article
- Inhibition of matrix metalloproteinase 9 activation by a specific monoclonal antibody Academic Article
- Interleukin-1-beta regulates human cytotrophoblast metalloproteinase activity and invasion in-vitro Academic Article
- MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs Academic Article
- Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels Academic Article
- Matrix metalloproteinase-9 mediates post-hypoxic vascular pruning of cerebral blood vessels by degrading laminin and claudin-5 Academic Article
- Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth doxorubicin with less toxicity Academic Article
- Matrix metalloproteinases and tumor metastasis Academic Article
- Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with alzheimer's disease Academic Article
- Matrix metalloproteinases increase very early during experimental focal cerebral ischemia Academic Article
- Microarray platform for profiling enzyme activities in complex proteomes Academic Article
- Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed alpha v beta 3 and alpha v beta 5 integrins Academic Article
- Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation Academic Article
- Microglial expression of alpha v beta 3 and alpha v beta 5 integrins is regulated by cytokines and the extracellular matrix: Beta 5 integrin null microglia show no defects in adhesion or mmp-9 expression on vitronectin Academic Article
- Mmp-2 and mmp-9 levels in peripheral blood after subarachnoid hemorrhage Academic Article
- Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after myocardial infarction Academic Article
- Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway Academic Article
- Participation of macrophages in atherosclerotic lesion morphology in LDLr-/- mice Academic Article
- Patterns of expression of fibrinolytic genes and matrix metalloproteinase-9 in dissecting aortic aneurysms Academic Article
- Production and regulation of gelatinase-b by human t-cells Academic Article
- Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients - influence of different therapies Academic Article
- Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity Academic Article
- Reduction of myocardial infarct size by doxycycline: a role for plasmin inhibition Academic Article
- Regulation of macrophage migration by a novel plasminogen receptor Plg-R(KT) Academic Article
- Role of matrix metalloproteinases 2 and 9 in lacrimal gland disease in animal models of Sjogren's syndrome Academic Article
- S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death Academic Article
- Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression Academic Article
- Targeting tumor cell-platelet interaction in breast cancer metastasis Academic Article
- The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules Academic Article
- The isolation, characterization, and molecular cloning of a 75-kda gelatinase b-like enzyme, a member of the matrix metalloproteinase (mmp) family - an avian enzyme that is mmp-9-like in its cell expression pattern but diverges from mammalian gelatinase b in sequence and biochemical properties Academic Article
- Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment Academic Article
- Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation Academic Article
- Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro Academic Article
- Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination Academic Article
- Use of gel zymography to examine matrix metalloproteinase (gelatinase) expression in brain tissue or in primary glial cultures Academic Article