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Matrix Metalloproteinase 9

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  • A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia  Academic Article
  • Activated integrin alpha v beta 3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells  Academic Article
  • Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage  Academic Article
  • Activation of matrix metalloproteinase-9 (mmp-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion  Academic Article
  • Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death  Academic Article
  • Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases  Academic Article
  • Anacardic acid inhibits the catalytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9  Academic Article
  • Angiogenic capacity of M1-and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9  Academic Article
  • Angiotensin type 1 receptor block age improves ischemic injury following transient focal cerebral ischemia  Academic Article
  • Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib  Academic Article
  • Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes  Academic Article
  • Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic balloon injury model  Academic Article
  • Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1  Academic Article
  • Cloning of rat 92-kda type iv collagenase and expression of an active recombinant catalytic domain  Academic Article
  • Differential regulation of cell motility and invasion by fak  Academic Article
  • EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation  Academic Article
  • Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis  Academic Article
  • Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice  Academic Article
  • Fibronectin- and vitronectin-induced microglial activation and matrix metalloproteinase-9 expression is mediated by integrins alpha(5)beta(1) and alpha(v)beta(5)  Academic Article
  • Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke  Academic Article
  • Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis  Academic Article
  • Inhibition of matrix metalloproteinase 9 activation by a specific monoclonal antibody  Academic Article
  • Interleukin-1-beta regulates human cytotrophoblast metalloproteinase activity and invasion in-vitro  Academic Article
  • MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs  Academic Article
  • Matrix metalloproteinase (MMP)-9 induced by Wnt signaling increases the proliferation and migration of embryonic neural stem cells at low O2 levels  Academic Article
  • Matrix metalloproteinase-9 mediates post-hypoxic vascular pruning of cerebral blood vessels by degrading laminin and claudin-5  Academic Article
  • Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth doxorubicin with less toxicity  Academic Article
  • Matrix metalloproteinases and tumor metastasis  Academic Article
  • Matrix metalloproteinases in peripheral blood and cerebrospinal fluid in patients with alzheimer's disease  Academic Article
  • Matrix metalloproteinases increase very early during experimental focal cerebral ischemia  Academic Article
  • Microarray platform for profiling enzyme activities in complex proteomes  Academic Article
  • Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed alpha v beta 3 and alpha v beta 5 integrins  Academic Article
  • Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation  Academic Article
  • Microglial expression of alpha v beta 3 and alpha v beta 5 integrins is regulated by cytokines and the extracellular matrix: Beta 5 integrin null microglia show no defects in adhesion or mmp-9 expression on vitronectin  Academic Article
  • Mmp-2 and mmp-9 levels in peripheral blood after subarachnoid hemorrhage  Academic Article
  • Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after myocardial infarction  Academic Article
  • Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway  Academic Article
  • Participation of macrophages in atherosclerotic lesion morphology in LDLr-/- mice  Academic Article
  • Patterns of expression of fibrinolytic genes and matrix metalloproteinase-9 in dissecting aortic aneurysms  Academic Article
  • Production and regulation of gelatinase-b by human t-cells  Academic Article
  • Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients - influence of different therapies  Academic Article
  • Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity  Academic Article
  • Reduction of myocardial infarct size by doxycycline: a role for plasmin inhibition  Academic Article
  • Regulation of macrophage migration by a novel plasminogen receptor Plg-R(KT)  Academic Article
  • Role of matrix metalloproteinases 2 and 9 in lacrimal gland disease in animal models of Sjogren's syndrome  Academic Article
  • S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death  Academic Article
  • Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression  Academic Article
  • Targeting tumor cell-platelet interaction in breast cancer metastasis  Academic Article
  • The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules  Academic Article
  • The isolation, characterization, and molecular cloning of a 75-kda gelatinase b-like enzyme, a member of the matrix metalloproteinase (mmp) family - an avian enzyme that is mmp-9-like in its cell expression pattern but diverges from mammalian gelatinase b in sequence and biochemical properties  Academic Article
  • Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment  Academic Article
  • Tumor-recruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation  Academic Article
  • Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro  Academic Article
  • Unexpected effect of matrix metalloproteinase down-regulation on vascular intravasation and metastasis of human fibrosarcoma cells selected in vivo for high rates of dissemination  Academic Article
  • Use of gel zymography to examine matrix metalloproteinase (gelatinase) expression in brain tissue or in primary glial cultures  Academic Article

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