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Guanine Nucleotide Exchange Factors

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  • A cell-cycle checkpoint monitors cell morphogenesis in budding yeast  Academic Article
  • A genome-wide association study of anorexia nervosa  Academic Article
  • Active nucleocytoplasmic shuttling required for function and regulation of stress-activated kinase Spc1/StyI in fission yeast  Academic Article
  • Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for beta-Pix in negative regulation of focal adhesion maturation  Academic Article
  • C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1  Academic Article
  • Cdk1 coordinates cell-surface growth with the cell cycle  Academic Article
  • Cellular and molecular determinants targeting the Caenorhabditis elegans PHR protein RPM-1 to perisynaptic regions  Academic Article
  • Cloning and sequencing of cDNA encoding mouse cytohesin-1  Academic Article
  • Conserved functions of membrane active gtpases in coated vesicle formation  Academic Article
  • Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition  Academic Article
  • Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH2 terminus in ER export  Academic Article
  • Designing orthogonal signaling pathways: How to fit in with the surroundings  Academic Article
  • Developmental function of the PHR protein RPM-1 is required for learning in Caenorhabditis elegans  Academic Article
  • FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles  Academic Article
  • Golgicide A reveals essential roles for GBF1 in Golgi assembly and function  Academic Article
  • Hippocampal phenotypes in kalirin-deficient mice  Academic Article
  • Identification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complex  Academic Article
  • Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes  Academic Article
  • Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function  Academic Article
  • Mise en place-this bud's for the Golgi  Academic Article
  • Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles  Academic Article
  • Neuronal development in Caenorhabditis elegans is regulated by inhibition of an MLK MAP kinase pathway  Academic Article
  • P21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized RHO exchange factor  Academic Article
  • Phosphorylation-dependent inhibition of Cdc42 GEF Gef1 by 14-3-3 protein Rad24 spatially regulates Cdc42 GTPase activity and oscillatory dynamics during cell morphogenesis  Academic Article
  • RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans  Academic Article
  • RPM-1 is localized to distinct subcellular compartments and regulates axon length in GABAergic motor neurons  Academic Article
  • RPM-1 regulates axon termination by affecting growth cone collapse and microtubule stability  Academic Article
  • RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development  Academic Article
  • Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development  Academic Article
  • Remedial strategies in structural proteomics: Expression, purification, and crystallization of the vav1/rac1 complex  Academic Article
  • Role for the rho-family gtpase cdc42 in yeast mating-pheromone signal pathway  Academic Article
  • Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network  Academic Article
  • Structural and functional organization of adp-ribosylation factor (arf) proteins  Academic Article
  • Structural basis of guanine nucleotide exchange mediated by the t-cell essential vav1  Academic Article
  • TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine  Academic Article
  • The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and beta-catenin  Academic Article
  • The PHR proteins: intracellular signaling hubs in neuronal development and axon degeneration  Academic Article
  • The dachshund gene is required for the proper guidance and branching of mushroom body axons in Drosophila melanogaster  Academic Article
  • The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export  Academic Article
  • The microtubule-associated RHO activating factor GEF-H1 interacts with exocyst complex to regulate vesicle traffic  Academic Article
  • Tlr2 signaling subpathways regulate tlr9 signaling for the effective induction of il-12 upon stimulation by heat-killed brucella abortus  Academic Article
  • Ubiquitin signals protein trafficking via interaction with a novel ubiquitin binding domain in the membrane fusion regulator, Vps9p  Academic Article

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