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Cyclin E

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  • A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1)  Academic Article
  • Accumulation of cyclin e is not a prerequisite for passage through the restriction point  Academic Article
  • Both scf(cdc4 alpha) and scf(cdc4 gamma) are required for cyclin e turnover in cell lines that do not overexpress cyclin e  Academic Article
  • Control of the g(1)/s transition  Academic Article
  • Cooperation between different cdc4/fbw7 isoforms may be associated with 2-step inactivation of scfcdc4 targets  Academic Article
  • Cyclin E deregulation promotes loss of specific genomic regions  Academic Article
  • Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1)  Academic Article
  • Cyclin e dysregulation and chromosomal instability in endometrial cancer  Academic Article
  • Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland  Academic Article
  • Deregulated cyclin e induces chromosome instability  Academic Article
  • Deregulation of cyclin e in human cells interferes with prereplication complex assembly  Academic Article
  • Detection of low molecular weight derivatives of cyclin e1 is a function of cyclin e1 protein levels in breast cancer  Academic Article
  • Differential regulation of transcription of p21 and cyclin D1 conferred by TAF(II)250  Academic Article
  • Fbw7alpha and fbw7gamma collaborate to shuttle cyclin e1 into the nucleolus for multiubiquitylation  Academic Article
  • Hcdc4 gene mutations in endometrial cancer  Academic Article
  • Human f-box protein hcdc4 targets cyclin e for proteolysis and is mutated in a breast cancer cell line  Academic Article
  • Maturation of human cyclin e requires the function of eukaryotic chaperonin cct  Academic Article
  • Mdm4 (mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development  Academic Article
  • Mutation of hcdc4 leads to cell cycle deregulation of cyclin e in cancer  Academic Article
  • Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry  Academic Article
  • Ratchets and clocks: The cell cycle, ubiquitylation and protein turnover  Academic Article
  • Reduced spermatogonial proliferation and decreased fertility in mice overexpressing cyclin e in spermatogonia  Academic Article
  • The induction of microrna-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest  Academic Article
  • Ubiquitylation of cyclin e requires the sequential function of scf complexes containing distinct hcdc4 isoforms  Academic Article
  • p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis  Academic Article

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