subject area of
- A bifunctional molecule that displays context-dependent cellular activity Academic Article
- A cross-strand Trp-Trp pair stabilizes the hPin1 WW domain at the expense of function Academic Article
- A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state Academic Article
- An analysis of the expression of cyclophilin-c reveals tissue restriction and an intriguing pattern in the mouse kidney Academic Article
- An endoplasmic reticulum-specific cyclophilin Academic Article
- Calcineurin is a common target of cyclophilin-cyclosporine-a and fkbp-fk506 complexes Academic Article
- Chain dynamics of nascent polypeptides emerging from the ribosome Academic Article
- Characterization of native protein complexes using ultraviolet photodissociation mass spectrometry Academic Article
- Chemical tools for studying the impact of cis/trans prolyl isomerization on signaling: a case study on RNA polymerase II phosphatase activity and specificity Academic Article
- Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation Academic Article
- Conformational polymorphism of cyclosporine-a Academic Article
- Context-dependent contributions of backbone hydrogen bonding to β-sheet folding energetics Academic Article
- Cooperation between different cdc4/fbw7 isoforms may be associated with 2-step inactivation of scfcdc4 targets Academic Article
- Crystal structure of TM1367 from Thermotoga maritima at 1.90 Å resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold Academic Article
- Crystal structure of the complex of brugia malayi cyclophilin and cyclosporin a Academic Article
- Cyclophilin inhibitors for the treatment of HCV infection Academic Article
- Cyclophilin-A is bound through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex Academic Article
- Cyclosporine-a - cyclophilin complex-formation - a model based on x-ray and NMR data Academic Article
- Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function Academic Article
- Destabilization of the complete protein secondary structure on binding to the chaperone groel Academic Article
- Determination of the NMR solution structure of the cyclophilin-a - cyclosporine-a complex Academic Article
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect Academic Article
- Engineering a beta-sheet protein toward the folding speed limit Academic Article
- Evaluating beta-turn mimics as beta-sheet folding nucleators Academic Article
- Fbw7alpha and fbw7gamma collaborate to shuttle cyclin e1 into the nucleolus for multiubiquitylation Academic Article
- High-resolution mapping of the folding transition state of a WW domain Academic Article
- Host cyclophilin A mediates HIV-1 attachment to target cells via heparans Academic Article
- Human immunodeficiency virus type 1 hijacks host cyclophilin A for its attachment to target cells Academic Article
- Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques Academic Article
- Increasing protein stability using a rational approach combining sequence homology and structural alignment: stabilizing the WW domain Academic Article
- Influence of hPin1 WWN-terminal domain boundaries on function, protein stability, and folding Academic Article
- Inhibition of calcineurin by a novel fk-506-binding protein Academic Article
- Multiple cycles of global unfolding of groel-bound cyclophilin a evidenced by NMR Academic Article
- N-PEGylation of a reverse turn is stabilizing in multiple sequence contexts, unlike N-GlcNAcylation Academic Article
- NMR solution structure of the isolated Apo Pin1 WW domain: comparison to the X-ray crystal structures of Pin1 Academic Article
- Nucleotide-sequence of a cdna coding for mouse cyclophilin Academic Article
- Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease Academic Article
- Protein native-state stabilization by placing aromatic side chains in N-glycosylated reverse turns Academic Article
- Sequence determinants of thermodynamic stability in a ww domain. An all-beta-sheet protein Academic Article
- Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code Academic Article
- Structural basis for high-affinity peptide inhibition of human Pin1 Academic Article
- Structure discrimination for the c-terminal domain of escherichia coli trigger factor in solution Academic Article
- Structure of human cyclophilin and its binding-site for cyclosporine-a determined by x-ray crystallography and NMR-spectroscopy Academic Article
- Structure-function-folding relationship in a WW domain Academic Article
- Synthesis of a negatively charged dibenzofuran-based beta-turn mimetic and its incorporation into the WW miniprotein-enhanced solubility without a loss of thermodynamic stability Academic Article
- The NMR solution conformation of unligated human cyclophilin A Academic Article
- The NMR structure of cyclosporine-a bound to cyclophilin in aqueous-solution Academic Article
- The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus Academic Article
- The effect of backbone cyclization on the thermodynamics of beta-sheet unfolding: Stability optimization of the PINWW domain Academic Article
- Three-dimensional structure and actions of immunosuppressants and their immunophilins Academic Article
- Toward assessing the position-dependent contributions of backbone hydrogen bonding to β-sheet folding thermodynamics employing amide-to-ester perturbations Academic Article
- Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA Academic Article
- Ubiquitylation of cyclin e requires the sequential function of scf complexes containing distinct hcdc4 isoforms Academic Article
- p1B15: a cDNA clone of the rat mRNA encoding cyclophilin Academic Article