subject area of
- A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase Academic Article
- A dynamic model of HIV integrase inhibition and drug resistance Academic Article
- Active site binding modes of curcumin in HIV-1 protease and integrase Academic Article
- Blind prediction of HIV integrase binding from the SAMPL4 challenge Academic Article
- Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome Academic Article
- Discovery of a distinct chemical and mechanistic class of allosteric HIV-1 integrase inhibitors with antiretroviral activity Academic Article
- Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation Academic Article
- First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G Academic Article
- Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein e2c direct integration of viral DNA into specific sites Academic Article
- Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein e2c can bias integration of viral DNA into a predetermined chromosomal region in human cells Academic Article
- Identification of efficiently cleaved substrates for HIV-1 protease using a phage display library and use in inhibitor development Academic Article
- New class of HIV-1 integrase (IN) inhibitors with a dual mode of action Academic Article
- Recombinant rabbit single-chain antibodies bind to the catalytic and c-terminal domains of hiv-1 integrase protein and strongly inhibit hiv-1 replication Academic Article
- Single-particle image reconstruction of a tetramer of hiv integrase bound to DNA Academic Article
- Structural basis for strand-transfer inhibitor binding to HIV intasomes Academic Article
- The food of sweet and bitter fancy Academic Article
- The integrase interactor I (INII) proteins facilitate Tat-mediated human immunodeficiency virus type I transcription Academic Article
- Virtual screening of integrase inhibitors by large scale binding free energy calculations: the SAMPL4 challenge Academic Article
- Virtual screening with AutoDock Vina and the common pharmacophore engine of a low diversity library of fragments and hits against the three allosteric sites of HIV integrase: participation in the SAMPL4 protein-ligand binding challenge Academic Article