subject area of
- 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies Academic Article
- A blueprint for HIV vaccine discovery Academic Article
- A candidate live inactivatable attenuated vaccine for aids Academic Article
- A comparative immunogenicity study of hiv-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120 Academic Article
- A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals Academic Article
- A live-virus ''suicide'' vaccine for human immunodeficiency virus Academic Article
- A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene Academic Article
- A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies Academic Article
- A structure-based approach to a synthetic vaccine for hiv-1 Academic Article
- A vaccine for hiv type 1: The antibody perspective Academic Article
- AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges Academic Article
- An engineered mutant of hiv-1 gp120 formulated with adjuvant quil a promotes elicitation of antibody responses overlapping the cd4-binding site Academic Article
- Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis b surface antigen particles Academic Article
- Another HIV vaccine failure: where to next? Academic Article
- Anti-HIV B Cell lines as candidate vaccine biosensors Academic Article
- Anti-human immunodeficiency virus type 1 (hiv-1) antibodies 2f5 and 4e10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize hiv-1 Academic Article
- Antibody 2g12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the hiv-1 glycan shield if domain exchanged Academic Article
- Antibody neutralization of hiv-1 and the potential for vaccine design Academic Article
- Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design Academic Article
- Antibody responses to envelope glycoproteins in HIV-1 infection Academic Article
- Antibody vs. HIV in a clash of evolutionary titans Academic Article
- Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy Academic Article
- B cell liaison confounds HIV-1 evolution Academic Article
- B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates Academic Article
- Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus Academic Article
- Blys-mediated modulation of naive b cell subsets impacts hiv env-induced antibody responses Academic Article
- Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface Academic Article
- Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target Academic Article
- Broad neutralization coverage of HIV by multiple highly potent antibodies Academic Article
- Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses Academic Article
- Broadly neutralizing antibody responses in a large longitudinal Sub-Saharan HIV primary infection cohort Academic Article
- Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers Academic Article
- CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies Academic Article
- Challenges for structure-based HIV vaccine design Academic Article
- Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization Academic Article
- Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation Academic Article
- Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design Academic Article
- Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Academic Article
- Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies Academic Article
- Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic hiv vaccine epitope Academic Article
- Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design Academic Article
- Covalent linkage of HIV-1 trimers to synthetic liposomes elicits improved B cell and antibody responses Academic Article
- Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer Academic Article
- Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design Academic Article
- Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design Academic Article
- Cta1-dd adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization Academic Article
- Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds Academic Article
- Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant Academic Article
- Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Academic Article
- Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity Academic Article
- Dissection of the carbohydrate specificity of the broadly neutralizing-anti-hiv-1 antibody 2g12 Academic Article
- Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization Academic Article
- Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice Academic Article
- Efficient neutralization of primary isolates of hiv-1 by a recombinant human monoclonal-antibody Academic Article
- Elicitation of simian immunodeficiency virus-specific cytotoxic t lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination Academic Article
- Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies Academic Article
- Enhanced mucosal immunoglobulin a response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system Academic Article
- Estimating the respective contributions of human and viral genetic variation to HIV control Academic Article
- Evaluation of gp160 vaccinees in the hu-PBL-SCID mouse model Academic Article
- Expanded breadth of virus neutralization after immunization with a multiclade envelope hiv vaccine candidate Academic Article
- Factors limiting the immunogenicity of hiv-1 gp120 envelope glycoproteins Academic Article
- Fc receptor but not complement binding is important in antibody protection against HIV Academic Article
- Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing Academic Article
- Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody Academic Article
- Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development Academic Article
- Genomics meets HIV-1 Academic Article
- Gp120: Biologic aspects of structural features Academic Article
- HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage Academic Article
- HIV vaccine design: Insights from live attenuated siv vaccines Academic Article
- HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogene Academic Article
- HIV-1 envelope evolution and vaccine efficacy Academic Article
- HIV-1 neutralizing antibodies induced by native-like envelope trimers Academic Article
- HIV-1 neutralizing antibodies induced by native-like envelope trimers Academic Article
- Heterologous envelope immunogens contribute to aids vaccine protection in rhesus monkeys Academic Article
- High-resolution definition of vaccine-elicited b cell responses against the hiv primary receptor binding site Academic Article
- High-throughput protein engineering improves the antigenicity and stability of soluble HIV-1 envelope glycoprotein SOSIP trimers Academic Article
- Hiv-1 and influenza antibodies: Seeing antigens in new ways Academic Article
- Hiv-1 env(gp140) trimers elicit neutralizing antibodies without efficient induction of conformational antibodies Academic Article
- Hiv-1 neutralization: Mechanisms and relevance to vaccine design Academic Article
- Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein Academic Article
- Hyperglycosylated mutants of human immunodeficiency virus (hiv) type 1 monomeric gp120 as novel antigens for hiv vaccine design Academic Article
- Immune Focusing and Enhanced Neutralization Induced by HIV-1 gp140 Chemical Cross-Linking Academic Article
- Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10 Academic Article
- Immunization with recombinant hla classes i and ii, hiv-1 gp140, and siv p27 elicits protection against heterologous shiv infection in rhesus macaques Academic Article
- Immunization with wild-type or cd4-binding-defective hiv-1 env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus Academic Article
- Immunogenic display of purified chemically cross-linked HIV-1 spikes Academic Article
- Immunogenicity of DNA vaccines expressing human immunodeficiency virus type 1 envelope glycoprotein with and without deletions in the v1/2 and v3 regions Academic Article
- Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines Academic Article
- Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes Academic Article
- In vitro antigen challenge of human antibody libraries for vaccine evaluation: The human immunodeficiency virus type 1 envelope Academic Article
- In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1 Academic Article
- Increased hiv-1 vaccine efficacy against viruses with genetic signatures in env v2 Academic Article
- Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization Academic Article
- Influence of novel cd4 binding-defective hiv-1 envelope glycoprotein immunogens on neutralizing antibody and t-cell responses in nonhuman primates Academic Article
- Inhibition of hiv-1 entry by antibodies: Potential viral and cellular targets Academic Article
- Lessons from the cat: Feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1 Academic Article
- Limited or no protection by weakly or nonneutralizing antibodies against vaginal shiv challenge of macaques compared with a strongly neutralizing antibody Academic Article
- Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates Academic Article
- Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody Academic Article
- Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization Academic Article
- Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies Academic Article
- Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys Academic Article
- Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies Academic Article
- Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins Academic Article
- Neutralizing antibodies generated during natural hiv-1 infection: Good news for an hiv-1 vaccine? Academic Article
- Nonhuman primate models and the failure of the merck hiv-1 vaccine in humans Academic Article
- Nonneutralizing antibodies to the cd4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site Academic Article
- Phase 1 safety and immunogenicity evaluation of a multiclade hiv-1 DNA candidate vaccine Academic Article
- Phase 1 safety and immunogenicity evaluation of a multiclade hiv-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector Academic Article
- Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines Academic Article
- Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity Academic Article
- Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate Academic Article
- Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice Academic Article
- Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen Academic Article
- Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV Academic Article
- Rational HIV immunogen design to target specific germline B cell receptors Academic Article
- Rational Vaccine Design in the Time of COVID-19 Academic Article
- Rational antibody-based HIV-1 vaccine design: current approaches and future directions Academic Article
- Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to hiv-1 Academic Article
- Rational modifications of hiv-1 envelope glycoproteins for immunogen design Academic Article
- Recent advances in carbohydrate-based vaccines Academic Article
- Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs. Academic Article
- Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers Academic Article
- Relationship between antibody 2f5 neutralization of hiv-1 and hydrophobicity of its heavy chain third complementarity-determining region Academic Article
- Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design Academic Article
- Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates Academic Article
- Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160 Academic Article
- Rhesus macaque B-cell responses to an HIV-1 trimer vaccine revealed by unbiased longitudinal repertoire analysis Academic Article
- Selective expansion of hiv-1 envelope glycoprotein-specific b cell subsets recognizing distinct structural elements following immunization Academic Article
- Solution conformation of an immunogenic peptide derived from the principal neutralizing determinant of the HIV-2 envelope glycoprotein gp125 Academic Article
- Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein Academic Article
- Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins Academic Article
- Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 Academic Article
- Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers Academic Article
- Structural evolution of glycan recognition by a family of potent HIV antibodies Academic Article
- Structural insights into key sites of vulnerability on hiv-1 env and influenza ha Academic Article
- Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence Academic Article
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Academic Article
- Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site Academic Article
- Structure-based stabilization of hiv-1 gp120 enhances humoral immune responses to the induced co-receptor binding site Academic Article
- Structure-based vaccine design in hiv: Blind men and the elephant? Academic Article
- Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies Academic Article
- Targeting HIV-1 gp41 in close proximity to the membrane using antibody and other molecules Academic Article
- The challenges of eliciting neutralizing antibodies to hiv-1 and to influenza virus Academic Article
- The development of cowpea mosaic virus as a potential source of novel vaccines Academic Article
- The hiv-1 envelope glycoproteins: Fusogens, antigens, and immunogens Academic Article
- The membrane-proximal external region of hiv-1 gp41: A vaccine target worth exploring Academic Article
- The neutralizing antibody response to hiv-1: Viral evasion and escape from humoral immunity Academic Article
- Toward an aids vaccine Academic Article
- Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Academic Article
- VRX-496(VIRxSYS) Academic Article
- Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign Academic Article
- Vaccine-elicited tier 2 HIV-1 neutralizing antibodies bind to quaternary epitopes involving glycan-deficient patches proximal to the CD4 binding site Academic Article
- Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties Academic Article