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Antigens, CD8

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  • A role for cd81 in early t cell development  Academic Article
  • Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine  Academic Article
  • Activated and memory cd8(+) t cells can be distinguished by their cytokine profiles and phenotypic markers  Academic Article
  • Activation of macrophage CD8: pharmacological studies of TNF and IL-1 beta production  Academic Article
  • Altered peptide ligands induce delayed CD8-T cell receptor interaction--a role for CD8 in distinguishing antigen quality  Academic Article
  • An hla-c-restricted cd8+ cytotoxic lymphocyte-t clone recognizes a highly conserved epitope on human-immunodeficiency-virus type-1 gag  Academic Article
  • Analysis of pancreas-infiltrating t-cells in diabetic nod mice - fusion with bw5147 yields a high-frequency of islet-reactive hybridomas  Academic Article
  • Anti-perform antibody treatment ameliorates experimental crescentic glomerulonephritis in wky rats  Academic Article
  • CD4+8- and CD4-8+ mature thymocytes require different post-selection processing for final development  Academic Article
  • CD4+CD8- thymocytes from neonatal mice induce IgM production in SCID mice  Academic Article
  • CD4-CD8- thymocytes that express the T-cell receptor may have previously expressed CD8  Academic Article
  • CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes  Academic Article
  • CD8αα and ‐αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I  Academic Article
  • Cd81 expressed on human thymocytes mediates integrin activation and interleukin 2-dependent proliferation  Academic Article
  • Cell surface immunoglobulin regulated checkpoints in chicken B cell development  Academic Article
  • Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas  Academic Article
  • Characterization of immature CD4+CD8-CD3- thymocytes  Academic Article
  • Cloned human cd4+ cytotoxic t lymphocytes specific for toxoplasma gondii lyse tachyzoite-infected target cells  Academic Article
  • Co-receptors and recognition of self at the immunological synapse  Academic Article
  • Commitment to the T-cell receptor-alpha-beta or receptor-gamma-delta lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes  Academic Article
  • Constitutive activation of integrin alpha 4 beta 1 defines a unique stage of human thymocyte development  Academic Article
  • Counteraction of HLA-C-mediated immune control of HIV-1 by Nef  Academic Article
  • Crystal structure of the TCR co-receptor CD8 alpha alpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution  Academic Article
  • Development of immature thymocytes - initiation of CD3, CD4, and CD8 acquisition parallels down-regulation of the interleukin-2 receptor alpha-chain  Academic Article
  • Developmental expression of the alpha(iel)beta(7) integrin on t-cell receptor-gamma-delta and t-cell receptor-alpha-beta t-cells  Academic Article
  • Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice  Academic Article
  • Evidence for heterogeneous TCR V-beta repertoire expression in mercury-induced immune disorders in rats  Academic Article
  • Feline immunodeficiency virus infects both cd4+ and cd8+ lymphocytes-t  Academic Article
  • Focal expression of interleukin-2 does not break unresponsiveness to self (viral) antigen expressed in beta-cells but enhances development of autoimmune-disease (diabetes) after initiation of an anti-self immune-response  Academic Article
  • HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen  Academic Article
  • Human CD8 transgene regulation of HLA recognition by murine T cells  Academic Article
  • Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD8  Academic Article
  • In vivo anergized T cells form altered immunological synapses in vitro  Academic Article
  • In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection  Academic Article
  • In vivo-activated cd4 t cells upregulate cxc chemokine receptor 5 and reprogram their response to lymphoid chemokines  Academic Article
  • Infected cd8 alpha(-) dendritic cells are the predominant source of il-10 during establishment of persistent viral infection  Academic Article
  • Infection of lymphocytes by a virus that aborts cytotoxic lymphocyte-t activity and establishes persistent infection  Academic Article
  • Interference with major histocompatibility complex class-ii-restricted antigen presentation in the brain by herpes-simplex virus type-1 - a possible mechanism of evasion of the immune-response  Academic Article
  • Lcmv-specific, class-ii restricted cytotoxic t-cells in beta-2-microglobulin deficient mice  Academic Article
  • Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor  Academic Article
  • Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro  Academic Article
  • Mechanisms of class-I restricted immunopathology - A transgenic mouse model of fulminant-hepatitis  Academic Article
  • Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse  Academic Article
  • Novel CD8 molecule on macrophages and mast cells: expression, function and signaling  Academic Article
  • OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor  Academic Article
  • Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells  Academic Article
  • Proliferative arrest and cell cycle regulation in cd8(+)cd28(-) versus cd8(+)cd28(+) t cells  Academic Article
  • Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with notch receptor ligation  Academic Article
  • Regulation of thymus size by competition for stromal niches among early T cell progenitors  Academic Article
  • Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8  Academic Article
  • Species-restricted interactions between CD8 and the alpha 3 domain of class I influence the magnitude of the xenogeneic response  Academic Article
  • Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen-presenting cells in vivo  Academic Article
  • Supine orientation of a murine MHC class I molecule on the membrane bilayer  Academic Article
  • TOX provides a link between calcineurin activation and CD8 lineage commitment  Academic Article
  • The T cell receptor's α-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation  Academic Article
  • The acquisition of CD4 and CD8 during the differentiation of early thymocytes in short-term culture  Academic Article
  • The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I  Academic Article
  • The proliferative in vivo activities of ipr double-negative t cells and the primary role of p59(fyn) in their activation and expansion  Academic Article
  • Thymic selection of the human T-cell receptor V-beta repertoire in SCID-HU mice  Academic Article
  • Thymic selection threshold defined by compartmentalization of ras/mapk signalling  Academic Article
  • Thymic skewing of the cd4/cd8 ratio maps with the t-cell receptor alpha-chain locus  Academic Article
  • Thymus-grafted scid mice show transient thymopoiesis and limited depletion of v-beta-11+ t-cells  Academic Article
  • Timing of deletion of autoreactive V-beta-6+ cells and down-modulation of either CD4 or CD8 on phenotypically distinct CD4+8+ subsets of thymocytes expressing intermediate or high-levels of T-cell receptor  Academic Article
  • Tolerance-related v-beta clonal deletions in normal cd4-8-, tcr-alpha/beta+ and abnormal lpr and gld cell-populations  Academic Article
  • Transgenic mice expressing human hla and cd8 molecules generate hla-restricted measles virus cytotoxic t lymphocytes of the same specificity as humans with natural measles virus infection  Academic Article
  • Unrestricted recognition of a nonpeptide antigen by CD8+ cytolytic T lymphocytes  Academic Article
  • V-beta repertoire of murine hepatic T-cells - implication for selection of double-negative alpha-beta(+) T-cells  Academic Article
  • Viral targeting of hematopoietic progenitors and inhibition of dc maturation as a dual strategy for immune subversion  Academic Article
  • Virus encoding an encephalitogenic peptide protects mice from experimental allergic encephalomyelitis  Academic Article
  • Virus-induced immunosuppression - immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression  Academic Article
  • Virus-induced immunosuppression .1. Age at infection relates to a selective or generalized defect  Academic Article
  • Virus-infection triggers insulin-dependent diabetes-mellitus in a transgenic model - role of anti-self (virus) immune-response  Academic Article
  • Visualizing intermolecular interactions in T cells  Academic Article

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