subject area of
- A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response Academic Article
- Autoantibodies as reporters identifying aberrant cellular mechanisms in tumorigenesis Academic Article
- Bcl-2 is an apoptotic target suppressed by both c-myc and e2f-1 Academic Article
- Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: Studies with the model tumor antigen beta-galactosidase and the BALB/c Meth A p53 tumor-specific antigen Academic Article
- Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72 Academic Article
- Deletions linked to TP53 loss drive cancer through p53-independent mechanisms Academic Article
- Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland Academic Article
- Disruption of the arf-mdm2-p53 tumor suppressor pathway in myc-induced lymphomagenesis Academic Article
- Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: Kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity Academic Article
- Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex Academic Article
- Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations Academic Article
- Identification of a p53 binding-site in the human retinoblastoma susceptibility gene promoter Academic Article
- Identification of p53 regulators by genome-wide functional analysis Academic Article
- Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1 Academic Article
- Immune response to cyclin B1 in hepatocellular carcinoma Academic Article
- Isolation of streptonigrin and its novel derivative from Micromonospora as inducing agents of p53-dependent cell apoptosis Academic Article
- Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress Academic Article
- MaRX: an approach to genetics in mammalian cells Academic Article
- Mdm2 haplo-insufficiency profoundly inhibits myc-induced lymphomagenesis Academic Article
- Meaning of autoantibodies in lupus-like syndromes Academic Article
- Mouse models for generating p53 gene mutation spectra Academic Article
- Multiple oncogenes and tumor suppressor genes are structurally and functionally intact during hepatocarcinogenesis in hepatitis B virus transgenic mice Academic Article
- Myc pathways provoking cell suicide and cancer Academic Article
- Myc signaling via the arf tumor suppressor regulates p53-dependent apoptosis and immortalization Academic Article
- Nucleophosmin is required for DNA integrity and p19(Arf) protein stability Academic Article
- Nucleotide excision repair phenotype of human acute myeloid leukemia cell lines at various stages of differentiation Academic Article
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function Academic Article
- Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy Academic Article
- The molecular perspective: P53 tumor suppressor Academic Article
- UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin Academic Article
- [A preliminary study on p53 gene expression and infection of human papilloma virus in laryngeal squamous cell carcinoma] Academic Article
- p53 designer genes for the modern mouse Academic Article
- p53-independent role of MDM2 in TGF-β1 resistance Academic Article